id
stringlengths
36
36
question
stringlengths
1
1.57k
opa
stringlengths
1
287
opb
stringlengths
1
287
opc
stringlengths
1
286
opd
stringlengths
1
301
cop
class label
4 classes
choice_type
stringclasses
2 values
exp
stringlengths
1
22.5k
subject_name
stringclasses
21 values
topic_name
stringlengths
3
135
8598e316-344a-482a-be19-b09a144d3bdb
Eustachian tube opens in middle ear in-
floor
anterior wall
Superior wall
Posterior wall
1b
multi
70. Ans: b. Anterior wall (Refer: PL Dhingra, Diseases of Ear, Nose & Throat, 7th edition, pg no. 61) Eustachian tube   Cylindrical channel connecting tympanic cavity & nasopharynx called Pharyngotympanic tube Opens in the anterior wall of middle ear Epithelium – Ciliated columnar epithelium Length – 36 mm (Lateral 1/...
Unknown
null
a8b6a200-daaa-426e-a047-0dc78d7f553a
Erythema chronicum migrans is seen in ?
Lyme's disease
Glucagonoma
Gastrinoma
Phaeochromocytoma
0a
single
'a' i.e. Lyme's disease
Surgery
null
da5fe51b-16fe-4dc8-83d2-d7357745b467
Sympathetic stimulation has following effect on insulin release
Stimulation
Inhibition
Inhibition followed by stimulation
No effect
1b
single
Sympathetic stimulation decreases the release of insulin Ref: guyton and hall textbook of medical physiology 12 edition page number:610,611,612
Physiology
Nervous system
eb7adaf2-cb4a-4acc-a89b-bfd88dc6ca71
In a child admitted with H. Influenza meningitis, Cefotaxime was staed instead of ampicillin. Which of these is the likely reason for this?
H. influenzae stains known to produce Beta lactamase
H. influenzae stains known to have altered penicillin binding protein
More easier to give
It is cheap
0a
single
Ans. (a) H. influenzae stains known to produce Beta lactamase Approximately 20-35% of nontypable strains of hemophilus produce 13-lactamase. In addition to 0-lactamase alteration of penicillin binding proteins is a second mechanism of ampicillin resistance has been detected in isolates of H. influenzae.
Microbiology
null
a91fdf88-872d-44c7-85fd-439514fedf16
With respect to ticlopidine, clopidogrei:
Is more likely to cause formation of antiplatelet antibodies
15 less likely to cause neutropenia
Is more likely to cause severe bleeding
Has a greater antiplatelet effect
1b
single
(Ref: KDT 6/e p610) Ticlopidine and clopidogrel are ADP antagonists and are used as antiplatelet drugs. Antiplatelet action, chances of bleeding and formation of antibodies is similar with these two agents. Clopidogrel is better tolerated because it is less likely to cause severe neutropenia and thrombocy topenia as co...
Pharmacology
Other topics and Adverse effects
0176fac7-0022-4e81-a369-33323f1f87f1
Feature of Henoch-Scholein purpura includes -a) Occur only in elderly personb) Palpable purpurac) Thrombocytopeniad) Arthralgia
bd
d
ab
ac
0a
single
null
Medicine
null
745f3aa6-fc9f-4d66-920e-ca63604b734c
Floor of Petit triangle is formed by-
Sacrospinalis
Internal oblique
Rectus abdominis
Fascia Transversalis
1b
single
Ans. is 'b' i.e., Internal oblique The lumbar triangle (Petit's triangle) is a weak area in the posterior part of the abdominal wall. It is bounded anteriorly by the posterior margin of the external oblique muscle, posteriorly by the anterior border of the latissimus dorsi muscle, and inferiorly by the iliac crest. The...
Anatomy
Lower Extremity
df44b2c3-bbcb-4daf-9bd1-db22a5548736
Glucose transpoer in myocyte?
GLUT 1
GLUT 2
GLUT 3
GLUT 4
3d
single
D i.e. GLUT 4
Physiology
null
27605f01-5a2c-4a2b-93cb-322c5d28f6c4
Time taken for conversion of CIN cervix to invasive carcinoma is - years :
5
10
15
20
1b
single
10
Gynaecology & Obstetrics
null
36b186a8-5011-45b4-890c-60f801eabfe3
What is Nitroblue tetrazolium test used for?
Phagocytosis
Complement
T cell
B cell
0a
single
. Phagocytosis
Pathology
null
4a6c7a86-db8a-4441-befa-000701b36846
Which of the coagulation factor is least affected in a patient with vitamin K deficiency?
Factor 10
Factor 9
Factor 8
Factor2
2c
single
Factor VIII Patient with vitamin K deficiency will have mostly involvement of dependent clotting factors. I.e. Factors II, VII, IX & X
Pathology
Clotting system
16e6f9f4-ec1c-4883-b2a5-53859e96d36a
All are true about sphincter urethrae except
Voluntary
Supplied by Pudendal nerve
Originates from the ischiopubic rami
Located at bladder neck
3d
multi
The urethral sphincter is two muscles used to control the exit of urine in the urinary bladder through the urethra. Two muscles either the female or male, external urethral sphincter and internal urethral sphincter. ref - BDC vol2 pg376,380
Anatomy
Abdomen and pelvis
30940d25-a86b-4212-bde4-87dda79cdce9
The following is a characteristic symptom of chronic pelvic inflammatory disease :
Dysuria
Constipation
Backache
Fever
2c
single
Backache
Gynaecology & Obstetrics
null
9d04431c-ef19-43c0-8dd0-46ae83ad5bfe
Onion skin thickening of aeriolar wall is seen in
Atherosclerosis
Median calcific sclerosis
Hyaline aeriosclerosis
Hyperplastic aeriosclerosis
3d
multi
Hyperplastic aeriolosclerosis is more typical of severe hypeension. Vessel exhibit onion skin , concentric laminated thickening of aeriolar walls and luminal narrowing Robbins 9 th edition page no. 334
Pathology
Cardiovascular system
d461a73e-b0aa-4619-985c-c8ac2518877e
A young lady presented with bilateral nodular lesions on shins. She was also found to have bilateral hilar lymphadenopathy on chest X-ray. Mantoux test reveals indurations of 5 mms. Skin biopsy would reveal:
Non caeseating Granuloma
Vasculitis
Caseating Granuloma
Malignant cells
0a
single
Ans. is 'a' Non caseating granulomas Skin lesions in this patient in Erythema nodosum.Erythema nodosum, bilateral hilar lymphadenopathy negative Mantoux test in strongly suggestive of sarcoidosis.Skin biopsy {or biopsy from hilar nodes, conjunctiva, lip, or spleen, intraabdominal nodes) would reveal non- caseating gran...
Unknown
null
63561008-8012-4318-aaf3-d0290839f975
Catecholamines are synthesized from ?
Tryptophan
Tyrosine
Methionine
Histidine
1b
single
Ans. is 'b' i.e., Tyrosine Catecholamines (epinephrine, norepinephrine and dopamine) are synthesized from tyrosin. Has been explained in previous seesions.
Biochemistry
null
234a096f-048f-4565-b73c-17df6510ddbf
Not a selective serotonin reuptake inhibitor:
Flouxetine
Fluvoxamine
Buspirone
Citalopram
2c
single
Buspirone
Psychiatry
null
20fdd1bb-4891-4964-8a1f-f44bbf8b17ea
Lipotropic factor are all except
Choline
Lecithin
Arginine
Methionine
2c
multi
Arginine Lipotropic factors are substances which prevent the accumulation of fat (TGs) in the liver. Primary lipotropic factors → choline, betaine, methionine, lecithin, inositol. Other factors with some lipotropic action:- Vitamin-B12, folic acid, casein, glycine, essential fatty acids, selenium, vitamin E and serine...
Biochemistry
null
8144898c-8366-4c05-beee-36b43892a31c
Bony nasal septal perforation is seen in?
Tuberculosis
Syphilis
Leprosy
Rhinosporidiosis
1b
single
Ans. (b) SyphilisRef: Dhingra 5thed p.166
ENT
Disease of External Nose & Nasal Septum
b9093edf-d615-4ecf-bd39-af93a9544742
Which chromosomal anomaly associated with alzheimer's dementia?
Trisomy 18
Trisomy 21
Patau syndrome.
Turners syndrome
1b
single
Several genes play impoant pathogenic roles in at least some patients with Alzheimer's disease(AD). One is the APP gene on chromosome 21. Adults with trisomy 21 (Down syndrome) consistently develop the typical neuropathologic hallmarks of AD if they survive beyond age 40. Presenilin-1 (PS-1) is on chromosome 14 and enc...
Psychiatry
null
7c6863be-5c1c-456e-a61e-43e020a49b05
The usual voltage of alpha rhythm is
5 mv
10 mv
50 mv
100 mv
2c
single
Alpha waves are neural oscillations in the frequency range of 8-12 Hz arising from the synchronous and coherent (in phase or constructive) electrical activity of thalamic pacemaker cells in humans. Ref: guyton and hall textbook of medical physiology 12 edition page number: 818,819,820
Physiology
Nervous system
a4adc3c3-3480-46d8-9d4c-43ae417d6d81
Commonly injured in blunt abdominal injury is/are -
Mid ileum
Prox. jejunum
Mid jejunum
Distal ileum
1b
single
Answer is 'b' i.e. Prox.Jejunum Small bowel is frequently injured after a penetrating injury After blunt trauma small bowel injury can be seen in 5-20% of patients who required laprotomy. Mechanism of injury of small bowel by blunt trauma Small bowel is injured by 3 postulated mechanisms 1) crushing of the bowel betwee...
Surgery
null
5036db49-08ef-4b15-ad89-bfeee88f0ed8
For a population of 10000, sex ratio of more than 1000 means
Males are less than 500
Females are less than 500
Females are less than 5000
Males are less than 5000
3d
single
In the given question Total population is 10,000. Also, Ideal sex ratio implies 5000 females for 5000 males So, Sex ratio is more than 1000, it implies, Females are more than 1000 per 1000 males Thus, females are > 5000 and males are < 5000
Social & Preventive Medicine
null
92a6214e-fac9-4af9-b808-bdd65b2a7356
Which of the following is not true regarding Wolff-Parkinson-White (WPW) syndrome?
No AV nodal delay
Delta wave is seen on ECG
Prolonged PR interval
Bundle of Kent
2c
multi
Wolff-Parkinson-White (WPW) syndrome Bundle of Kent is an aberrant anomalous path that connects SA node directly to the ventricles, bypassing the AV node. It is found in Wolff-Parkinson-White (WPW) syndrome There is no AV nodal delay. Hence, ventricular contraction stas very early, before its filling has occurs substan...
Physiology
FMGE 2019
6782a57d-b371-4020-9736-b3927916c8b6
Which of the following chemotherapeutic agents is specific for the M phase of the cell cycle?
Cytarabine
Daunorubicin
Hydroxyurea
Vincristine
3d
single
Vincristine (and vinblastine) are Vinca alkaloids that bind to tubulin, a component of cellular microtubules. This leads to disruption of the mitotic spindle apparatus and results in metaphase arrest since the chromosomes are unable to segregate. Since these drugs interfere with mitosis, they are considered cell-cycle ...
Pharmacology
null
9fcdcdd7-d864-415b-a30e-bf758e61036c
Mouth breathing is an example of
Compulsive habit
Non pressure habit
Meaningful habit
Useful habit
1b
single
Non pressure habits are habits, which do not apply a direct force on the teeth or its supporting structure. Mouth breathing is an example of non pressure habit.
Dental
null
47bf4cde-37a4-4f5f-991e-eeae38351698
In a patient on cisplatin therapy, which of the following diuretics would be preferred ?
Mannitol
Acetazolamide
Thiazide
Furosemide
0a
single
null
Pharmacology
null
717d3f25-b8c3-43b8-83e1-d85c7ecca78f
Boys over 16 years who are too difficult to be handled in a certified school or have misbehaved there are sent to a : -
Remand home
Borstal
Foster home
Any of the above
1b
multi
Borstals: Boys over 16 years who are too difficult to be handled in a certified school or have misbehaved there, are sent to a Borstal. Borstal, as an institution, falls between a certified school and an adult prison.  A borstal sentence is usually for 3 years, and is regarded as a method of training and reformation.
Social & Preventive Medicine
null
481bbca9-c745-40ec-b338-dddf6032ddc7
a child wins the first prize in school, he is given choclates that he likes, he tend to get high marks in future, this is what line of terapy
interpersonal therapy
behaviour therapy
dialectic therapy
dynamic therapy
1b
single
Behavioral therapy is learning given by BF Skinner , according to him all behaviors are learned phenomenon and thus can be unlearned Positive reinforcement a type of reinforcement when a behavior is rewarded there is more chance that the behavior is repeated Negative reinforcement is that when a behavior is done and an...
Anatomy
Treatment in psychiatry
388cc912-bc4b-490e-a359-dfcaf38aba2a
The serum concentration of which of the following human IgG subclasses is maximum?
IgG1
IgG2
IgG3
IgG4
0a
single
IgG is the major class of immunoglobulin present in the serum. The IgG molecule consists of two L chains and two H chains (H2L2). There are four subclasses of IgG: IgG1, IgG2, IgG3, and IgG4. Each subtype contains a distinct but related H chain and each differs somewhat regarding their biological activities. IgG1 repre...
Microbiology
Immunology
2e343ab3-b9bc-4058-999b-57bc379e3489
Bucky diaphragm?
Reduces scattered radiation
Reduces response time
Decreases long wavelength rays
Decreases kVp and mA requirement
0a
single
Potter Bucky grid is a type of moving grid. These devices reduce the amount of scattered radiation reaching the film while still allowing the patterns containing the primary beams to reach the film. The image of radiolucent grid lines on the film can be deleted by moving the grid perpendicular to the direction of grid ...
Radiology
null
55a05a9c-3e27-4f4e-8b6c-347a65387c15
Spinocerebellum is involved in:
Maintainance of postural balance
Smoothening and coordination of movements
Planning and programming of movements
Initiation of skilled voluntary movements
1b
single
Vestibulocerebellum (flocculonodular lobe) concerned with equilibrium (postural balance) and eye movements. Spinocerebellum is responsible for smoothening and coordination of movements. Cerebrocerebellum has role in planning and programming of movements. Initiation of skilled voluntary movements: Coical association are...
Physiology
Nervous System
2bf4af66-b302-4995-9c6b-93cfcca777cc
Treatment of contaminated wound in Gas Gangrene isa) Debridement of woundb) Systemic penicillinc) Metronidazole Administrationd) Peroxide dressings
ac
ab
ad
bc
1b
single
null
Surgery
null
2dca49d5-3dec-4856-923c-020cf232838d
Total T3 T4 and TSH all decrease in
Primary hypothyroidism
Hypopituitarism
Nephrotic syndrome
Pregnancy
1b
multi
(B) Hypopituitarism
Biochemistry
Miscellaneous (Bio-Chemistry)
2f00464b-b29b-4ac2-9246-1b70377abb1a
Marked dermatome is
L4
L5
S1
S2
3d
single
Dermatome supply of the marked area is S2
Anatomy
Nerve supply of Lower Limb
703d9208-a8d5-43cd-af29-0dd0ce8c4510
Which of the following is commonest source of Extradural haemorrhage:
Middle meningeal artery
Subdural venous sinus
Charcot's artery
Middle cerebral artery
0a
single
Ans is 'a' ie Middle meningeal artery (Ref. Chandrasoma Taylor, 3/e, p 924)"Extradural Haemorrhage is an accumulation of blood between the skull and the dura. In 90% of cases, bleeding is from a branch of the middle meningeal artery". ChandrasomaAlso remember *Subdural Haemorrhage, commonest source is - communicating v...
Surgery
Traumatic Brain Injury
b9b9edd0-fd1c-4c4e-87f7-d5e3636a72df
"Dentitia Tarda".
Resorption of the deciduous dentition
Premature loss of the deciduous dentition
Retarded eruption of deciduous dentition
Early eruption of deciduous dentition
2c
single
null
Dental
null
87656262-d27f-40f5-b734-bdce6b31882a
Characteristic of Bacillus cereus food poisoning is
Presence of fever
Presence of pain in abdomen
Absence of vomiting
Absence of diarrhoea
1b
single
Bacillus cereus is an impoant cause of food poisoning. Two patterns: diarrheal and emetic. Diarrheal: associated with cooked meat and vegetables. Diarrhea and abdominal pain 8-16 hours after the ingestion of contaminated food. Vomiting rarely. Bacilli are not found in the fecal specimen of these patients. Emetic: assoc...
Microbiology
Bacteriology
4a058d74-5272-4dd2-9db9-428b29260fb4
Which of the following is typical hanging
Knot is just below the chin
Knot is at occiput
Body is fully suspended
Legs are touching the ground
1b
single
Refer the byte "Hanging and strangulation".
Forensic Medicine
null
041a81a9-4c26-4e55-90f6-864f9a750504
In terms of bih defect potential, the safest of the following drugs is
Alcohol
Isotretinoin (Accutane)
Tetracyclines
Progesterones
3d
single
Alcohol sequelae include retardation of intrauterine growth, craniofacial abnormalities, and mental retardation. Isotretinoin, a drug for acne, is asoociated with congenital anomalies like Microtia, Micrognathia, cleft palate, thymic aplasia, CVS anomalies, NTDs Tetracyclines interfere with development of bone and can ...
Gynaecology & Obstetrics
Drugs in Pregnancy
28a9d52d-7884-48c8-b2f2-1cd1df53f80e
A toddler has few drops of blood coining out of rectum. Probable diagnosis is:(AIIMS May 2013, May 2012)
Juvenile rectal polyp
Adenomatous Polyposis Coli
Rectal ulcer
Piles
0a
single
Ans. a. Juvenile rectal polyp (Ref: Sabiston 19/e p1342; Schwartz 9/e p1043: Bailey 25/e p1228; Schackelford 7/e p2030; Harrison 19/e p537, 18/e p313, 352; 17/e p250)Most common cause of passage of few drops of blood per rectum in a toddler is Juvenile rectal polyp.Juvenile polypsJuvenile polyps are the MC type of colo...
Surgery
Rectum
61fd768b-1c26-4caa-b645-a0d544e7a0a8
According to Gutman's classification periapical surgery includes all except:
Periapical curettage
Root end resection.
Root end preparation.
Perforation repair.
3d
multi
GOT MAN’S CLASSIFICATION 1. Fistulative surgery I & D Cortical Trephination Decompression Pracedure 2. ieri Apical Surgery Periapical curellage Root end Resection Root end Preparation Root end Filling 3. Corrective Surgery Performation Repairs Pathological Performance Repair Iatrogenic Performance Repair Root Re...
Dental
null
5683f459-3d69-459d-9543-ab1961e8ac90
A 12 year old girl complains of pain persisting in his leg for several weeks with a low grade fever. A radiograph reveals a mass in the diaphyseal region of the left femur with overlying cortical erosion and soft tissue extension. A biopsy of the lesion shows numerous small round cells, rich in PAS positive diastase se...
Osteogenic sarcoma.
Osteoblastoma.
Ewing's sarcoma.
Chondroblastoma
2c
multi
Ans. is 'c' i.e. Ewing's Sarcoma Small round cells rich in PAS positive diastase sensitive granules confirms the diagnosis of Ewing's sarcoma.The histopathological features of Ewing's sarcoma are:Small round cells having scant cytoplasmThese cells are rich in glycogen* this glycogen filled cytoplasm is detected by stai...
Orthopaedics
Bone Tumour
bb6c011d-6212-4166-926e-049cdb0aa7e0
Spores of bacteria are destroyed by
Alcohol
Lysol
Halogen
Ionizing radiation
2c
single
Ans. is 'c' i.e., Halogen Amongst the given options, only halogens have sporicidal propey
Microbiology
null
928a9131-1f08-465c-b60a-7ac5f2ece884
Congenital rubella syndrome (CRS) is associated with all of the following EXCEPT?
Cataract
Sensory neural hearing loss
Congenital hea disease
Cherry Red spot
3d
multi
Cherry Red spot- not seen in congenital rubella syndrome. Congenital rubella syndrome (CRS) includes:-> Gregg's triad: Cataract Deafness (Sensorineural hearing loss) Congenital hea disease (Most common- PDA and less common-ASD) Rubella (German measles or 3-Day Measles) Mild , exanthematous disease Incubation period: 14...
Pediatrics
Congenital Infections
4d9e364e-5150-4a8c-b8db-0fde3b45640f
All are true about breastfeeding Except
It is available at proper temperature
Breastmilk contains antibodies
Exclusive breastfeeding upto 6 months of age
To be staed after 4 hours of normal delivery
3d
multi
All mothers should be suppoed to initiate breastfeeding as soon as possible after bih, within the first hour after delivery.Provision of mother's breast milk to infants within one hour of bih is referred to as "early initiation of breastfeeding" and ensures that the infant receives the colostrum, or "first milk", which...
Microbiology
All India exam
2a20ccdd-e840-4d9d-9cd2-cdf24655721b
One of the health benefits of the use of combined oral contraceptives in pre–menopausal women is that these contraceptives reduce the risk of:
Deep vein thrombosis
Migraine
Ovarian cancer
Ischemic stroke
2c
single
null
Pharmacology
null
384545c2-5891-4e76-8fe3-590c747f429a
Delayed labour occurs in:a) Early use of epidural anesthesia with analgesiab) Early use of analgesiac) Unripened cervixd) Preeclampsiae) Use of sedative early in course of labour
bcde
abce
acde
abde
1b
single
Delayed/prolonged labour: “Labour is said to be prolonged when the combined duration of the first and second stage is more than the arbitrary time limit of 18 hours or when the cervical dilatation rate is less than 1 cm/hr and descent of the presenting part is < 1 cm/hr for a period of 4 hours (WHO-1994).” Causes of Pr...
Gynaecology & Obstetrics
null
eaebad0a-f8b0-43c1-a14b-8743208da2dc
Outermost nuclei of the basal ganglia includes
Putamen
Globus pallidus
Substantia Niagra
Subthalmic nucleus
0a
multi
Ans. is 'a' i.e., Putamen * Basal ganglia include following nuclei:- caudate nucleus, putamen, globus pallidus, subthalamic nucleus and substantia nigra.* Putamen is the outermost basal ganglia nucleus lying just lateral to globus pallidus
Anatomy
Neuroanatomy
1d4756f6-6d8c-4bd2-8542-00a3fe2522c8
McMurray's test is useful clinical test to assess injury to?
Medial collateral ligamnet
Lateral collateral ligament
Meniscus injury
Crucitae ligament injury
2c
single
Ans. C. Meniscus injury. (Ref. Orthopedics by Ebnezar 4th/Pg. 257).A positive McMurray fs test is diagnostic of a meniscal injury.McMurray test# The McMurray test, also known as the McMurray circumduction test is used to evaluate individuals for tears in the meniscus of the knee. It is a rotation test for demonstrating...
Orthopaedics
Injuries Around the Thigh & Knee
127cf3ae-d323-4859-a497-7eea017e4359
Malonyl acetyl transferase has activity of how many enzymes?
1
2
3
4
1b
single
Malonyl acetyl transferase (MAT) is a pa of multienzyme complex : Fatty acid synthase.It has two activities:?Acetyl transferase or acetyl transacylase (E1)Malonyl transferase or malonyl transacylase (E2)
Biochemistry
null
fc6ef4cc-c679-4bad-b470-548c0205c0b5
Wucheria bancrofti, true is -
Unsheathed
Tail tip free from nuclei
Non-periodic
All
1b
multi
The somatic cells or nuclei appear as granules in the cental axis of the embryo and extend from the head to the tail end The granules do not extend into the tail end which is a distinguishing feature of Microfilaria bancrofti (refer pgno:165 baveja 3 rd edition)
Microbiology
parasitology
e64902d7-8894-4f47-9342-d72736810e10
A 40-year-old man underwent kidney transplantation. Two month after transplantation, he developed fever and feature suggestive of bilateral diffuse interstitial pneumonia. Which of the following is most likely etiologic agent?
Herpes simplex virus
Cytomegalovirus
Epstein-barr virus
Varicella , zoster virus
1b
single
Ans. (b) Cytomegalovirus Remember CMV is the MC infection complicating organ transplantation. CMV is MC cause of intrauterine infection. Risk of post-transplant CMV infection is greatest 5-13 weeks after transplant Infections after Kindeny Transplan Period after transplanatation Infection site Early (< 1 month) ttiddle...
Microbiology
null
e59d038a-1785-4938-b9be-57d93df402cc
All of the following statements are true about warfarin except:-
It inhibits activation of vitamin K dependent clotting factors
It can cross placenta
Its half-life is approximately 36 hours
Its dose should be increased in liver disease
3d
multi
WARFARIN It acts by inhibiting the activation of vitamin K dependent clotting factors. These factors include clotting factors II, VII, IX and X. Half life of warfarin is 36-48 hours. Bleeding is the most common adverse effect of all anticoagulants. If a patient develops bleeding due to overdose of warfarin, fresh froze...
Pharmacology
Hematology
8dd447c7-6a4e-4253-9fd5-79f55382b03a
Clinical effect of vitamin D is reduced by ?
Simultaneous ingestion of phytates
Simultaneous ingestion of lactose
Acidic environment
None
0a
multi
Ans. is 'a' i.e., Simultoneous ingestion of phytates The main clinical effect of vitamin D is to enhance intestinal absorption of calcium. With an average intake of 1000 mg of calcium its net intestinal absorption is only 150-250 mg/day. Calcium is absorbed mainly in the duodenum and jejunum (proximal intestine) by an ...
Pharmacology
null
da35797a-7923-4323-8728-f14e3a33d9fa
A newborn is found to have stridor. What is the the commonest cause of stridor in a newborn?
Laryngomalacia
Foreign body
Meconium aspiration
Recurrent laryngeal nerve palsy due to bih
0a
single
Laryngomalacia is the most common cause of stridor in infants, and is also the most common congenital laryngeal abnormality, accounting for approximately 60% of cases. Stridor occurs as a result of prolapse of the supraglottic structures into the laryngeal inlet on inspiration. Also know: Stridor is generally of laryng...
Pediatrics
null
2fb811f8-3f1a-4204-b0be-6a6acedaedb6
Isthmus of thyroid gland is across tracheal rings:
2nd - 4th
3rd - 5th
5th and 6th
4th only
0a
single
The isthmus of the thyroid gland extends across the midline in front of the 2nd, 3rd, and 4th tracheal rings.
Anatomy
null
b6a37377-a663-457e-bec1-9d857e6660a7
Enzyme defective in Maple syrup urine disease is:
Tyrosinase
Phenylalanine hydroxylase
Branched chain alpha ketoacid dehydrogenase
Homogentisate oxidase
2c
single
Enzyme deficiencies and conditionsTyrosinase is deficient in albinismPhenylalanine hydroxylase is deficient in phenylketonuriaMaple syrup urine disease is due to a defect in the enzyme branched chain alpha-keto acid dehydrogenaseHomogentisate oxidase is deficient in alkaptonuria
Biochemistry
null
a62afd03-c9d8-4035-9664-44028059d7ee
Which of the following is true about vasa previa except?
Incidence is 1 :1500
Mortality rate of 20% with undiagnosed case
Associated with low lying placenta
Cesarean section is indicated
1b
multi
Ans. is b, i.e. Mortality rate of 20% with undiagnosed caseRef Williams Obs 23/e, p 583-584, High risk pregnancy" Fernando Anas 3/e p 348, progress in Obs. and Gynae- John Studd vol. 17/e p 209Vasa previa: It is a condition in which the fetal blood vessels unsupported by either umbical cord or placental tissue, overlie...
Gynaecology & Obstetrics
Antepartum Haemorrhage
30fa4567-fd3d-4b9f-9658-cd28a9a37ac6
Flight of idea is seen in
Mania
Schizophrenia
Depression
Delirium
0a
single
A i.e. Mania
Psychiatry
null
e0c1ead0-6335-4de1-92e3-50f69aa1bd20
Use of filters result in:
Softer beam radiation
Wider beam coverage
Less penetrating beam
Beam of greater intensity
3d
single
Ans. Beam of greater intensity
Radiology
null
5935aa1d-83a3-45e5-a06c-d1559cf378f5
Management of extradural hemorrhage is -
Antibiotics
Immediate evacuvation
Evacuvation after 24 hrs.
Observation
1b
single
null
Surgery
null
48477a1a-07f4-4e41-868c-8586303acc71
Metabolic disorder leading to acute pancreatitis
Hypoparathyroidism
Hyperparathyroidism
Hypothyroidism
Hyperthyroidism
1b
single
(B) Hyperparathyroidism# Causes of Acute Pancreatitis> Common Causes Gallstones (including microlithiasis) Alcohol (acute and chronic alcoholism); Hypertriglyceridemia Endoscopic retrograde cholangiopancreatography (ERCP), especially after biliary manometry Trauma (especially blunt abdominal trauma) Postoperative (abdo...
Surgery
Miscellaneous
81ae110d-1fcb-49b0-8730-c5708df57388
A 60-year-old woman complains to a physician because several of her toe nails are discolored. Physical examination demonstrates crumbling, friable nails with distal-lateral separation from the nail bed. Hyperkeratotic debris is present under the affected pa of the nail. Which of the following is the most likely pathoge...
Aspergillus
Candida
Mucor
Trichophyton
3d
single
The patient has a fungal nail infection. These infections are seen most commonly in the elderly, and are usually caused by dermatophyte infection, typically Trichophyton rubrum, Trichophyton mentagrophytes, or Epidermophyton floccosum. Some of the more superficial lesions can be removed by simply scraping the fungus of...
Microbiology
null
a6c5e45a-2e37-4b5b-a8f8-fa09e4cc07af
Black colour code is used in four code system of triage management in disaster for -
Ambulatory pateints
Low priority pateints
Dead patients
High priority patients
2c
single
-triage consists of rapidly classifying the injured on the basis of severity of their injuries and the likelihood of their survival with prompt medical intervention. - black colour triage is for moribund and dead patients Reference: Park's textbook of preventive and social medicine, 23rd edition, pg no: 796 <\p>
Social & Preventive Medicine
Hospital waste and disaster management, Occupational health
0a7b0ba2-de9b-4682-b696-dfbbbfb7c4a7
In which of the following conditions Berlin&;s edema is
Open angle glaucoma
After cataract surgery
After concussional trauma
Diabetic retinopathy
2c
single
Blunt trauma to eye may produce Berlin&;s edema or commotio retinae Q which is a cloudy swelling characterized by a grey appaerance, most frequently in the temporal region. It may also manifest as cherry red spot in the foveal region. Ref: AK khurana 7th ed.
Ophthalmology
All India exam
ff3199c9-ac0a-446c-8577-ca24eed6f66a
The patient presented with chest pain to the emergency room and dies within 12 hours of arrival. After 5 days, autopsy shows necrosis in the Myocardium. What is the type of necrosis?
Coagulative
Fibrinoid
Caseous
Liquefactive
0a
single
Ans-ARef: Chapter I. Ceil injury; page: 15: Robbins and Cot ran Pathologic Basis of Disease: 8th edition).Explanation:Organs with end arterial blood supply will show usually the Coagulative type of necrosis; solid organs like a heart will always show Coagulative necrosis.Caseous necrosis is usually seen in tuberculosis...
Unknown
null
a48a478e-5cae-41ac-9fae-c59dd8992b9d
Commonest cause of Cerebral Infarction is:
Aerial thrombosis
Aeritis
Venous thrombosis
Lymphangitis
0a
single
Aerial thrombosis
Pathology
null
6251b91a-df05-4109-9254-39c4095bf632
Following is true about bronchial carcinoids -
Highly radiosensitive
Metastasis common
Carcinoid syndrome does not manifest
Commonly arise from terminal bronchioles
2c
multi
Ans. is 'c' i.e., Carcinoid syndrome does not manifest Bronchial carcinoid o Most patients < 40 years o Not related to smoking o Most tumors are confined to main stem bronchi and commonly project into lumen. Some tumors penetrate the bronchial wall to fan out in the peri-bronchial tissue producing the collar-button les...
Pathology
null
2b550fe0-8ae3-4345-ba60-165fb1d7a6d4
One of the following about corynebacterium diphtheriae is wrong -
Gram negative
Ernest babes granules seen
Chinese letter pattern
Prevented by immunisation
0a
single
null
Microbiology
null
96eba8b0-923f-485e-8dc7-499a5f2d38ac
The most common virus causing acute coryza is?
Arena virus
Rhino virus
RSV
Influenza virus
1b
single
The common cold is the most common illness in humans Rhinovirus ( most commonly), Influenza, Parainfluenza, Coronavirus, Respiratory syncytial virus etc all lead to the common cold. (Ref: Cummings, 6th edition, Pg no. 725 )
ENT
Nose and paranasal sinuses
55c2a868-c47c-431e-8207-a91e2dd196c9
Which antiviral drug is used in both HIV an hepatitis B:-
Acyclovir
Abacavir
Emtricitabine
Enfuviide
2c
multi
Drugs used in treatment of both HIV and Hepatitis B: * Lamivudine * Emtricitabine * Tenofovir Acyclovir and Abacavir are protease inhibitors used in treatment of HIV. Enfuviritide is a Gp41 inhibitor, it inhibits the fusion of virus with host cell.
Pharmacology
Anti-Viral Drugs
786efe0b-4ef6-4853-b08d-0317cf308c3c
metaclopromide:
inhibit cholinergic smooth.muscle stimulation in the gastrointestinal tract
decrease lower esophageal spinchter pressure
stimulate D2 receptor
enhance colonic activity
3d
single
metaclopromide is aD2 receptor antagonist that increases cholinergic activity by inhibiting presynapyic D2 receptors in GIT . it increases LES tone that is also responsible for anti emetic action. it does not significantly increase colonic motility
Pharmacology
Gastrointestinal tract
2669c8c2-8014-4ad1-bf32-8fcb5d46dcb6
The genetically engineered &;golden rice&; is rich in -
b-carotene and magnesium
Folic acid and iron
b-carotene and iron
Folic acid and magnesium
2c
multi
<p> Golden rice: Variety of rice produced through genetic engineering to boisynthesize beta carotene, a precursor of vitamin A. It is indented to produce a foified food to be grown and consumed in areas with a shoage of dietary vitamin A. Golden rice differs from its parenteral strain by the addition of three beta caro...
Social & Preventive Medicine
Nutrition and health
23b69462-8363-4e58-aa78-4dec3fbfc0df
An excess of which of the following hormones may be associated with increased sensitivity to epinephrine?
Testosterone
Parathyroid
Insulin
Thyroid
3d
single
null
Pharmacology
null
66ef0278-34fb-4c53-900b-4e089e4b08dd
A patient with cancer received extreme degree of radiation toxicity. Fuher history revealed that the dose adjustment of a paicular drug was missed during the course of radiotherapy. Which of the following drugs required a dose adjustment in that patient during radiotherapy in order to prevent radiation toxicity -
Vincristine
Dactinomycin
Cyclophosphamide
6-Mercaptopurine
1b
single
Ans. is 'b' i.e., Dactinomycin o The patient was most probably taking a radiosensitiser i.e., drugs which increases the toxicity due to radiotherpy. o The dose of these drugs should be decreased during radiotherapy o Among the drugs given in the question Actinomycin D or Dactinomycin is a radiosensitizer o Hypoxic cell...
Pharmacology
null
d6448fcc-7a36-4a8c-87ca-fafce439f12d
Which of the following drug is not given in acute mania: September 2009
Lithium
Lamotrigine
Valproate
Olanzapine
1b
single
Ans. B: Lamotrigine Lamotrigine is not recommended for acute mania. It is especially useful in rapidly cycling bipolar depression.
Pharmacology
null
38950c23-1d75-4a8a-99f8-e7a5adf6d5e8
In Addison's disease drug to be given is -
Hydrocoisone
Betamethasone
Prednisolone
DOCA
0a
single
Ans. is 'a' i.e., Hydrocoisone o In Addison's disease, there is chronic insufficiency of adrenal hormones. o Both glucocoicoids and mineralocoicoids are deficient, therefore treatment includes combination of glucocoicoids and mineralocoicoid to replace the adrenal insufficiency. o Hydrocoisone along with fludrocoisone ...
Pharmacology
null
97216218-a389-419d-9d45-99325256275a
Which of the following technique is not based on the buccal flaps in the management of oro-antral fistula?
Rehrmann Flap
Ashley Flap
Moczain Flap
Burger Flap
1b
single
null
Surgery
null
25147197-6764-41bb-8ade-f1bd9a656fb6
Which does not has a known animal reservoir
Brucella melitensis
Bordettela peussis
Pasturella multocida
Francisella tularensis
1b
single
Ans. is. 'b' i. e., Bordettela peussis
Microbiology
null
0f813ac1-1f8a-4786-a51e-5b1b2e3c2475
All of the following are the components of the white pulp of spleen, except
Periaeriolar lymphoid sheath
B cells
Antigen presenting cells
Vascular sinus
3d
multi
The spleen contains two main types of tissue - white pulp and red pulp. White pulp is lymphatic tissue (material which is pa of the immune system) mainly made up of white blood cells. Red pulp is made up of blood-filled cavities (venous sinuses) and splenic cords. <img src=" /> Ref - BDC 6e vol2 pg297
Anatomy
Abdomen and pelvis
46afe3c5-898d-4f5b-9ccf-a357852c3798
Congenital dislocations
Scurvy
Rickets
Polio
Osteomalacia
0a
single
Ans. is 'a' i.e., Scurvy
Pediatrics
null
6f7a66c0-93d8-474f-a645-f8916f0bfa58
Pulmonary complications of rheumatoid ahritis include the following except
Pulmonary nodules
Mesothelioma
Fibrosing alveolitis
pleural effusion
1b
multi
Pleural disease is the most common pulmonary manifestation of RA,may produce pleuritic chest pain,and dyspnea,as well as a pleural friction rub and exudative pleural effusion.Interstitial lung disease,like fibrosing alveolitis,can also occur in patients with RA.Pulmonary function testing shows a restrictive pattern wit...
Medicine
Respiratory system
93b37b3b-f724-4e63-87a6-4141b0854c5f
Mondor's disease is ?
Thrombophlebitis of the Superficial veins of Breast
Carcinoma of the breast
Premalignant condition of the breast
Filariasis of the breast
0a
single
Ans is 'a' i.e., Thrombophlebitis of Superficial veins of Breast Mondor's disease is thrombophlebitis of the superficial veins of anterior chest wall and breast although it has also been seen in the arm. frequently involved veins are lateral thoracic vein, thoracoepigastric vein and superficial epigastric veins. aetiol...
Surgery
null
d4ac310c-2289-42ef-a179-33e3ada42818
The enzyme deficient is Lesch-Nyhan syndrome is:
GT
Glutaminase
Transcarboxylase
HGP
3d
single
D i.e. HGP
Biochemistry
null
9bc0a24e-c3fe-43f6-bf9d-1df73d65299e
Stage- II testicular teratoma is treated by-
Orchidectomy + RPLND
Orchidectomy + Chemotherapy
Orchidectomy
Radiotherapy
0a
single
• Most common testicular tumor in prepubertal adults: Teratoma • Tumor is composed of two or more embryonic germ cell layers that may be both mature and immature. • Tumor is very heterogeneous with both solid and cystic components. Teratoma is divided into three subsets 1. Mature: well-differentiated ectodermal, mesode...
Surgery
null
a66f6340-3cb5-492d-b1ed-ae795bc348f3
Niemann-Pick disease is characterized by:
Increased concentration of sphingomyelin in liver
Increased concentration of cerebrosides in liver and spleen.
Increased concentration of plasminogen
Increased accumulation of glycerol in liver
0a
single
Ans. A. Increased concentration of sphingomyelin in liverNiemann -pick disease is due to the absence of sphingomyelinase enzyme which leads to the accumulation of sphingolipids or sphingomyelin in liver.
Biochemistry
Lipids
96d384af-72f0-4348-982f-e9c77903a4a4
A pregnant mother at 32 weeks gestation presents in preterm labour. Therapy with antenatal steroids to induce lung maturity in the fetus may be given in all of the following conditions except :
Prolonged rupture of membranes for more than 24 hours
Pregnancy induced hypeension
Diabetes mellitus
Chorioamnionitis
3d
multi
Ans. Is d i.e. Chorioamnionitis "Coicosteroids can be given even in presence of maternal hypeension or diabetes mellitus, but should preferably be avoided if PROM is associated with definitive evidence of chorioamnionitis" "Steroid treatment is contraindicated in presence of ove infection." ... Fernando Arias 3/e, p 22...
Gynaecology & Obstetrics
null
d34a058c-349f-48ba-a62b-5e7ac1dce3d3
Which of the following statements is NOT TRUE about NSAIDs ?
Acetyl salicylic acid is an irreversible inhibitor of COX enzyme.
Acetylsalicylic acid reduces in vivo synthesis of prostaglandins.
Its clearance is independent of plasma concentration
Antiplatelet effect of low dose aspirin is related to pre-systemic COX inhibition
2c
multi
null
Pharmacology
null
87d3bcf9-4c6b-46e0-94bd-fbe4484d2743
Tracking of BP implies:
BP increase with age
BP decreases with age
BP of normotensive becomes hypertensive
BP of hypertensive remains hypertensive
3d
single
Ans. (d) BP of hypertensive remain hypertensiveRef : K. Park 23rd ed. / 374Park 3rd / P 374 States:If BP of a person is tracked from early childhood to adult life then those individuals whose blood pressure was initially high in the distribution, would probably continue in the same "track".
Social & Preventive Medicine
Non-Communicable Diseases
fbc5ca20-4355-4187-a24a-405a9d3992d8
35 year ahas presented with 2 episodes of hematemesis. On examination his pulse rate is 100/min with BP of 90/60 mm Hg. Per abdomen examination shows spleen palpable 3 cm below costal margin. Which is true about this patient?
Elevated CRP and Low C3
Most common site of bleeding is First pa of duodenum
Urgent Elective intubation of patient
The increased pressure of poal vein pressure should be lowered with octreotide
3d
multi
Hematemesis + splenomegaly- Poal hypeension Elevated CRP + Low C3 (Only with inflammatory condition) Most common site of bleeding in 1st pa of duodenum - Peptic ulcer disease Urgent reflective intubation - bleeding esophageal varices The increased pressure of poal vein pressure should be lowered with octreotide - poal ...
Medicine
Bleeding from the GUT and diseases of esophagus
6d0f5223-e90b-41f7-a877-bd290e07030c
Supine hypotension is characteristic of :
1st trimester
2nd trimester
3rd trimester
Twin pregnancy
2c
single
3rd trimester
Gynaecology & Obstetrics
null
69f60982-081e-49d6-ba58-2c062f0e5408
Hydrostatic test is done in ?
Dry drowning
Wet drowning
Near drowning
Infanticide
3d
single
Ans. is 'd' i.e., Infanticide Hydrostatic test (lung float test or docimasia), is used in determining whether lungs have undergone respiration. It has been employed in cases of suspected infanticide to help determine whether or not an infant was stillborn.In the test, lungs that float in water are thought to have been ...
Forensic Medicine
null
734c0c77-967d-4e7a-b587-b8beb04cc55e
A 3-year-old child comes with hydrocele of the hernia sac. Management will include:
Herniotomy
Herniorrhaphy
Observation only
Operate after 5 years of age
0a
single
Ans. a. Herniotomy (Ref: Sabiston 191120-1126; Schwartz 9/1318-1331, Bailey 26/111, 1382; Schackelford 7/568-579)Management of hydrocele of the hernia sac (congenital hydrocele) in a 3 years old child is herniotomy."A patent processus vaginalis may allow only peritoneal fluid to track down around the testis to form a h...
Surgery
Inguinal Hernias
660a560e-cf9e-42f8-b54b-84bff7b9188f
Insulin increases the following pathways in liver EXCEPT:
Fatty acid synthesis
Glycogen synthesis
Protein synthesis
Glucose synthesis
3d
multi
Hormonal regulation Insulin generally favours all pathways which decrease blood glucose level by dephosphorylating the regulatory enzymes of these pathways In other words enzymes active under the influence of insulin is active in the dephosphorylated state. Glucagon generally favor all pathways which increase blood gl...
Biochemistry
null
08333107-0e8f-4170-aa42-361ddbc7174d
Figure of 8 in chest X-ray ?
Supracardiac TAPVC
Tetralogy of fallot
TGA
None of above
0a
multi
Ans. is 'a' Supracardiac TAPVC Teralogy of fallot--* boot shaped hea Transposition of great vessel-* egg on side TPVC (supracardioe) --> snownan or figure of 8 configuration
Pediatrics
null
15dd97cd-038f-4dd7-8c6c-3937dd3bbb6c
In dacryocystorhinostomy operation the communication of the sac is established with:
Middle meatus
Superior meatus
Inferior meatus
All of the above
0a
multi
Ans. Middle meatus
Ophthalmology
null
ec2f2a58-a335-4a9d-a574-5c20903de980
Scrub typhus is transmitted by: March 2011, March 2013 (d, e, g)
Flea
Mite
Tick
Louse
1b
single
Ans. B: Mite Vector for Scrub typhus is trombiculid mite Scrub typhus/Bush typhus It is a form of typhus caused by Orientia tsutsugamushi first isolated and identified in 1930 in Japan Scrub typhus is transmitted by some species of trombiculid mites ("chiggers", paicularly Leptotrombidium deliense), which are found in ...
Social & Preventive Medicine
null
2196eb77-c59a-4287-9d87-6e7074512ec7
Muscles forming floor of pelvis are all except-
Pubococcygeus
Iliococcygeus
Ischiococcygeus
Iliacus
3d
multi
Ans. is 'd' i.e., Iliacus * The pelvic floor is formed by the levator ani muscle which consists of three parts.1. Pubococcygeus2. Iliococcygeus3. Ischiococcygeus
Anatomy
Abdomen & Pelvis
2417cd3a-696b-4734-9051-ab7bee377eb7
At which level does methionine enter the TCA cycle?
Acetyl co A
Succinyl co A
Oxaloacetate
Pyruvate
1b
single
Reference: Lehninger illustrated biochemistry 5th edition
Biochemistry
Metabolism of protein and amino acid