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135
3342a49a-b0c3-4296-8cdc-a64d8f18d5a8
Characteristic feature of the urine in diabetes insipidus include the following EXCEPT
Has no proteins
Has no sugar
Specific gravity > 1.020
No casts
2c
multi
Ans. c (Specific gravity > 1.020). (Ref. Harrison, Medicine, 18th. Ch. 340 and 44)Fluid deprivation test: If fluid deprivation does not result in urine concentration (osmolarity >300 mosmol/L, specific gravity >1.010) before body weight decreases by 5% or plasma osmolarity/sodium rise above the upper limit of normal, t...
Medicine
Endocrinology
e4908255-aaed-4abb-a411-d064ade90893
The structures passing posterior to diaphragm are all except ?
Aoa
Azygous vein
Thoracic duct
Greater splanchnic nerve
3d
multi
The aoa passess posterior to the diaphragm.Accompanying the aoa through the aoic hiatus is the thoracic duct and the azygous vein.The greater and lesser splanchinic nerves passess through the crura on either side.
Anatomy
null
9b3918b0-8dcb-4429-8cb3-4e2adef4b1b1
In cryptorchidism, hallmark histological changes appear in testis at:
4 months
6 months
8 months
1 year
3d
multi
Histopathology- Abnormal germ cell histology- 1-2 Years:* Earliest change - Hypoplasia of Leydig cells (1 month of age)- Degeneration of Seoli Cells- Delayed disappearance of gonocytes- Delayed appearance of adult dark spermatogonia
Surgery
Testis and scrotum
e5d2d45d-5d09-4109-a001-1482c349897d
All are features of iridocyclitis except
Pain
Mucopurulent discharge
Constricted pupil
Circum corneal congestion
1b
multi
Ans) b (Mucopuntlent discharge) Ref: Kansk, 6th ed p447-448Mucopurulent discharge is seen in conjunctivitis Symptoms of iridocyclitis-Sudden onset painPhotophobiaRednessLacrimationSignsVisual acuity decreased,Circumcomeal congestionMiosisKeratic precipitatesAqueous cells and flare, hypopyon occAnterior vitreous cellsPo...
Ophthalmology
Uveal Tract
b80734e0-a8d1-41f9-8214-0456f5b6d1a5
Thymoma is associated with -
Myasthenia gravis
Scleroderma
Oesophageal atresia
Hypergammaglobulinemia
0a
single
null
Medicine
null
437c9d67-e2a3-473c-9192-3d7396752adc
Which enzyme is inhibited by fomepizole
Alcohol dehydrogenase
Acetaldehyde dehydrogenase
Catalase
Peroxidase
0a
single
null
Biochemistry
null
d5df13a4-6bcb-40d0-8a54-f568364df593
The local anaesthetic with the longest duration of action is :
Procaine
Chlorprocaine
Lignocaine
Dibucaine
3d
single
* Longest acting, most potent and most toxic LA is dibucaine. * Chlorprocaine is the shoest acting LA.
Pharmacology
Anaesthesia
892a3177-6689-4f33-9404-9a894605f8d7
Among all the layers of the scalp which layer is highly vascular?
Skin
Subcutaneous tissue
Aponeurosis
Loose connective tissue
1b
multi
Scalp consists of the overlying soft tissues as well as underlying calvarium. The soft tissues composing the scalp are skin, connective tissue (subcutaneous), aponeurosis (galea aponeurotica), loose areolar connective tissue, and pericranium. The connective tissue layer (subcutaneous) contains the vast majority of the ...
Anatomy
null
6b342cec-65ae-41ac-9d3f-6a6f651bcf02
Multifactorial causation of disease theory was proposed by
Louis Pasteur
Pettenkofer
Robe Koch
Aristotle
1b
single
Traits and conditions that are caused by more than one gene occurring together are multifactorial, and diseases that are caused by more than one factor interacting (for example, heredity and diet in diabetes) are multifactorial. Ref: 25th edition, Park's Textbook of Preventive and Social Medicine, Page no. 40
Social & Preventive Medicine
Concept of health and disease
dcbdfa33-8de2-4fb2-9377-306c3a26e9d3
Predisposing factors for skin cancer are-a) Smokingb) U-V-light c) Chronic ulcerd) Infrared light
bc
c
ac
ad
0a
single
Exposure to Sun (UV rays) Major predisposing factors.                    o Old burn scars Industrial carcinogens (Tars and oils)                                                    o Ingestion of arsenicals Chronic ulcers and draining osteomyelitis.                                           o Ionizing radiation Note : ...
Pathology
null
4cb37de5-785c-4841-863e-ec734ff97e1e
A 58-year-old man with cirrhosis complains of worsening fatigue and confusion over the past 5 days. He also repos that over the past 48 hours he has had a declining urinary output. On examination, he is gaunt and jaundiced. He has tense ascites and a liver span of 7 cm in the midclavicular line. Lab result reveals a WB...
Large volume paracentesis
Hemodialysis
Mesocaval shunt
Liver transplantation
3d
single
This patient with well-advanced cirrhosis and poal hypeension has developed the onset of renal insufficiency consistent with hepatorenal syndrome. This occurs during the end stages of cirrhosis and is characterized by diminished urine output and low urinary sodium. In the setting of end-stage liver disease, renal vasoc...
Medicine
G.I.T
fd229d6b-b5f1-44b1-93c7-399c6249847a
False about eukaryotic protein synthesis is:
N formyl Met is the first-RNA to come into action
mRNA read from 5' to 3'
Eft shift between GDP to GTP
Capping helps in attachment of mRNA to 40 S ribosome
0a
multi
A i.e. N formyl Met is the first - RNA to come into action
Biochemistry
null
064894d5-3208-4cff-bb7f-1d82b31a4293
Loosening of association is an example of -
Formal thought disorder
Schneider's first symptoms
Perseveration
Concrete thinking
0a
single
Ans. is 'a' i.e., Formal thought disorder Thought disordersFormal thought disorders (Disorders of thought process)Disorders of thought contenti) Racing thoughts :- Anxiety, Schizophreniaii) Retarded thoughts :- Depressioniii) Circumstantiality :- Mania, Schizophreniaiv) Thought blocking :- Schizophrenia, Severe anxiety...
Psychiatry
Cognitive Development
717ab440-fea6-4bb9-917f-e144173cd782
Epstein-Barr virus (EBV) VCA-IgG 1 :80 and EBV antibody to early antigen EA1 :320 suggest which one of the following diseases?
Chronic infectious mononucleosis
Primary syphilis
Scarlet fever
Primary atypical pneumonia
0a
single
Infectious mononucleosis (IM) may be suspected clinically but it is confirmed serologically. The heterophil antibody test, however, may be negative in up to 15% of adults and 35 to 40% of children. Because IM is caused by Epstein-Barr virus (EBV), a specific test for viral capsid antigen (VCA) of EBV is indicated when ...
Microbiology
Immunology
06d0f069-0ccd-4b32-8fa4-1205ee2c7a81
Chyluria is caused by all except: March 2007
Pregnancy
Childbih
Filariasis
Bile duct stones
3d
multi
Ans. D: Bile duct stones Chyluria/chylous urine is a condition involving the presence of chyle in the urine stream, which results in urine appearing milky white. Chyluria is often caused by filariasis due to the parasite Wuchereria bancrofti, a thready nematode which lodges the lymph channels. Another cause is pregnanc...
Surgery
null
ec2bb273-11fe-4327-8769-3483ce37affc
Most common organ affected in polyarteritis nodosa?
Lungs
Kidneys
Pancreas
Spleen
1b
single
Ans. b (Kidneys). (Ref. Harrisons Medicine, 18th/ Chapter 326. The Vasculitis Syndromes)PAN is necrotising vasculitis of small and medium sized arteries.Descending order of frequency of involvement of organs in PAN is# Kidney# Heart# Liver# GIT# Muscle# Pancreas# Testis# CNS# Skin
Pathology
Blood Vessels
a82ee225-fa3b-4fa6-afa3-51bc69aaec26
A patient with blunt trauma of abdomen at 48 hours, USG shows normal, but patient had tenderness in left lumbar region. Best appropriate diagnosis is by:
MCU
IVP
CECT abdomen
Repeat USG
2c
single
Suspect - injury of kidney in left abdomen. MCU is IOC for Vesicourethral Reflux IVP is IOC for Ureterocele
Surgery
DNB 2018
4dc014a1-9646-4cc5-974a-51d881eba0f4
An addict presents with increased sweating, lacrimation, diarrhea, yawning and rhinorrhea. These symptoms may occur due to withdrawal of ?
Heroin
Cocaine
Cannabis
Alcohol
0a
single
null
Pharmacology
null
56d5d8d7-3ea1-445e-bb19-bf8c7757dac2
Insulin acts on glucose metabolism by
| permeability of glucose across cell membrane
| permeability of glucose across cell membrane against glucose gradient
| permeability of renal cells
| glucose transpo to brain
1b
single
Insulin signals the cells of insulin-sensitive peripheral tissues, primarily skeletal muscle, to increase their uptake of glucose.Secondly, insulin acts on the liver to promote glycogenesis.Finally, insulin simultaneously inhibits glucagon secretion from pancreatic a-cells, thus signalling the liver to stop producing g...
Biochemistry
Endocrinology
b7cb0a91-a1e6-408e-95b4-2e770de7ed09
Medullary cystic disease of the kidney is best diagnosed by -
Ultrasound
Nuclear scan
Urography
Biopsy
3d
single
null
Medicine
null
e6fbfea4-9d36-4767-8c0f-bcde9bca2d37
Which is wrong about the treatment of condition shown?
Maximum fluid than be removed safely per sitting is 500ml
Severe Hiccoughs is a contraindication to thoracentesis
Done with patient sitting in scapular line
If patient cannot sit, he should be at edge of bed, arm raised above level of head, head end elevated by 30o
0a
multi
CXR - Ellis S shaped curve CP angle blunting Pleural effusion Thoracocentesis: Done with patient sitting in scapular line If patient cannot sit, he should be at edge of bed, arm raised above level of head, head end elevated by 30deg Severe Hiccoughs is a contraindication to thoracentesis Max fluid can be removed safely...
Medicine
Pleural effusion & Pulmonary alveolar proteinosis
d988b2da-11db-4562-8a5d-d55976f95ee1
Bifurcations and trifurcations are most commonly observed in
Maxillary 1st premolar
Maxillary 2nd premolar
Mandibular 1st premolar
Mandibular 2nd premolar
2c
single
null
Dental
null
0b53f759-330d-4d16-885d-a80bfd2f96fc
HLA typing is useful in: September 2004
Blood grouping
Assessing prognosis of disease
Cancer therapy
Cases of parental dispute
3d
single
Ans. D i.e. Parental dispute
Microbiology
null
c416bff6-4f14-4b11-b3fe-f3f3c9066962
Chronic constipation in children is seen in all A/E?
Hirschspring disease
Jejunal polyp
Hypothyroidism
Stricture
1b
multi
Ans. is 'b' i.e., Jejunal polyp
Pediatrics
null
5267b489-ab65-4e47-97e9-b84f59d39fb2
Cardiac lesion in SLE cause -
Verrucous endocarditis
Valvular incompetence
Myocardial fibrosis
All of the above
3d
multi
null
Medicine
null
42b5d9e5-56e9-4fdb-b2e8-4d122f40c71f
Autoantibody specific for SLE -
ds DNA
Anti RO
Anticentromere
Anti topoisomerse
0a
single
Ans. is 'a' i.e., ds DNA Antinuclear antibodies in SLEo Systemic lupus erythematosus is characterized by bewildering array of autoantibodies, particularly antinuclear antibodies.o The antibodies are directed against an array of nuclear and cytoplasmic components of the cell, in addition a third group of antibodies is d...
Pathology
Autoimmune Diseases
b3248dd9-19e2-4131-9b37-5bd29c48fc4b
Which of the following drugs should not be administered concomitantly with warfarin as it decreases the effect of oral anticoagulants ?
Broad spectrum antibiotic
Cimetidine
Aspirin
Oral contraceptive
3d
single
null
Pharmacology
null
07efdae6-6a17-4319-a33e-4a0d5f7374c3
Which of the following accessory ligaments of the TMJ is likely to have significance upon mandibular movements?
Sphenomandibular
Stylomandibular
Pterygomandibular
All of the above
1b
multi
The stylomandibular ligament is formed due to thickening of the investing layer of deep cervical fascia, which separates the parotid and submandibular glands. This ligament also becomes taut when the mandible is protruded. The accessory ligaments of temporomandibular joints control range of motion (ROM) of TMJs and wit...
Anatomy
null
e233d65b-4427-49be-93c2-8015ab8a0e87
The commonest true benign tumour of the bone is
Osteoma
Osteoid osteoma
Osteoblastoma
Osteochondroma
1b
multi
OSTEOID OSTEOMA It is the commonest true benign tumour of the bone. Pathologically, it consists of a nidus of tangled arrays of paially mineralised osteoid trabeculae surrounded by dense sclerotic bone. Clinical presentation: The tumour is seen commonly between the ages of 5-25 years. The bones of the lower extremity a...
Orthopaedics
Tumors
81a5d44e-8bde-4784-9af4-a83ffefc6def
As deglutition involved voluntary and involuntary stages, so among the following, which structure limits the size of bolus swallowed:
Soft palate
Posterior pharyngeal pillars
Upper esophageal sphincter
Larynx
1b
multi
null
Physiology
null
d6ed5699-a8c0-40a1-b5d7-f53cb379b408
Type of inheritance in Tuberous sclerosis -
Autosomal dominant
Autosomal recessive
X-linked dominant
X-linked recessive
0a
single
Ans. is 'a' i.e., Autosomal dominant
Pathology
Central Nervous System
1c41ffba-2830-4590-956b-c4a714a4b50c
In normal adult wave V of ABR is generated from
Cochlear nucleus
Superior olivary complex
Lateral leminiscus
Inferior colliculus
2c
single
Wave I - Distal pa of CN VIII Wave II - Proximal pa of CN VIII near the brainstem Wave III - Cochlear nucleus Wave IV - Superior olivary complex Wave V - Lateral lemniscus Waves VI and VII - Inferior colliculus Note: Auditory brainstem response (ABR): Also called BAER or BAEP (brainstem auditory evoked response or pote...
ENT
Ear
19053972-322c-4bd7-a0bb-a930cfe7fce7
Umblicated nodules are produced by?
Poxvirus
Enterovirus
Rhinovirus
Myxovirus
0a
single
Ans. is 'a' i.e., Poxvirus Nodules with central umblication is produced in molluscum contagiosum, caused by a Poxvirus.
Microbiology
null
6315e2a2-94a5-4226-832f-bfa3b89b17fc
All of the following are essential amino acids include all, EXCEPT:
Valine
Methionine
Lysine
Alanine
3d
multi
The essential amino acids are leucine, isoleucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine, and histidine. Protein is required for growth and for maintenance of body structure and function. The true requirement is for nine essential amino acids plus additional nitrogen for protein synthesis. Ad...
Biochemistry
null
ff16f2de-f713-4018-845b-5c94e78089a2
Syndrome of inappropriate antidiuretic hormone secretion (SIADH) causes
Euvolemic hyponatremia
Hypovolemic hyponatremia
Hypervolemic hyponatremia
Hypernatremia
0a
single
The syndrome of inappropriate antidiuresis (SIAD) is the most frequent cause of euvolemic hyponatremia. Glucocoicoid deficiency, Hypothyroidism, Stress, Drugs are other causes of euvolemic hyponatremia. Common causes of SIAD include pulmonary disease (e.g., pneumonia, tuberculosis, pleural effusion) and central nervous...
Medicine
Fluid and electrolytes
fd52cc53-873e-4f95-8b58-149fe1da8a3d
All of the following are true about case control study except -
Rapid and inexpensive
No risk to subjects
Risk factor can be identified
Less prone to bias
3d
multi
Ans. is 'd' i.e., Less prone to bias Case control studyo Case control study is a common first approach to test causal hypothesis.o Caseo Control--Case is an individual who has developed the disease.Is an individual who has not developed the disease but is otherwise comparable to case (e.2. age, sex, occupation, social ...
Social & Preventive Medicine
Analytical Epidemiology
b5478ba5-7e3b-4397-bc0c-82e3411c164e
True statements about congenital megacolon include all of the following except:
Dilatation & hyper trophy of pelvic colon
Loud borborygmi
Symptoms appear with in 3 days following birth
Large stool
3d
multi
S. Das writes - "The symptoms appear within 3 days of birth and the presenting features are as follows: Constipation Abdominal distention" Nelson writes - "The clinical symptoms of Hirschprung disease usually begin at birth with the delayed passage of meconium." Loud borborygmi are heard due to intestinal obstructi...
Surgery
null
9bf2e6d8-5a0f-4629-bce4-643a95dc2548
Which of the following remnant of wolffian duct is present on medial part of broad ligament
Epoophoran
Kobelt tubercle
Paroophoran
Gartner's duct
2c
single
All remnants of wolffian duct are present in lateral part of broad ligament except paroophoron.
Gynaecology & Obstetrics
null
24f12653-f46f-445f-9c3c-bfc5835a529b
WHO stage IV HIV includes all, except -
Toxoplamosis
Pneumocystis carinii
HIV wasting syndrome
Oral thrush
3d
multi
<p> Oral thrush is not included in the clinical stage 4 for HIV. Reference:Park's textbook of preventive and social medicine,K.Park,23rd edition,page no:349.<\p>
Social & Preventive Medicine
Communicable diseases
5f338d3a-66a1-4487-b2e0-12315c8e14b1
A 55-yrs-old woman complains of stiff, aching hands, especially in the morning. Radiographs of the hands reveal expansion at the base of the terminal phalanges & tapering of the proximal phalanges. This patient most likely has:
SLE
Rheumatoid arthritis
Psoriatic arthritis
Gouty arthritis
2c
multi
There are three main varieties of psoriatic arthritis (an inflammatory arthritis affecting 5 to 42% of patients with psoriasis): asymmetric inflammatory arthritis, symmetric arthritis , and psoriatic spondylitis. The pathology is similar to that seen in RA (early neutrophil and later monocytic synovial infiltration). T...
Unknown
null
0b74cd43-53e5-4458-abf3-67da20c1ec34
Amide group containing amino acid is:
Asparate
Glutamine
Glutamate
Glutamic acid
1b
single
Amide (-CONH) group is present in:- Asparagine Glutamine Asparagine is the amide of Aspaate Glutamine is the amide of Glutamate
Biochemistry
Classification and metabolism of amino acids
3baf86ce-6bdc-43e2-828a-546943241a45
All are true regarding superior laryngeal nerve block, except:
Needle pierces through thyrohyoid membrane
Sensory loss below level of vocal cords occurs
Internal laryngeal nerve is anesthetized
Thyroid notch is used as a landmark
1b
multi
Superior laryngeal nerve supplies sensory supply to the mucosa of larynx upto the level but not including the vocal cords. Sensory supply of vocal cords and larynx below vocal cords is by recurrent laryngeal nerve. Thus in superior laryngeal nerve block, sensory supply below the level of vocal cords will be maintained.
Surgery
null
e0be218a-000a-422e-a954-cf26db367e68
About ureter true is
5 cm long
25 cm long
35 cm long
Totally retroperitoneal
1b
multi
Abdominal ureter. The ureter is roughly 25-30 cm long in adults and courses down the retroperitoneum in an S curve. At the proximal end of the ureter is the renal pelvis; at the distal end is the bladder. The ureter begins at the level of the renal aery and vein posterior to these structures . Ref - BDC 6e vol2 pg 318
Anatomy
Abdomen and pelvis
c57c2506-0c5d-4950-bbda-494d03eef2b9
A patient is taking ketoconazole for fungal infection develops cold for which he is prescribed terfenadine. Possible interaction between terfenadine and ketoconazole is
Ketoconazole decreases metabolism of terfenadine
Terfenadine increases levels of ketoconazole
Ketoconazole decreases levels of terfenadine
No interaction
0a
single
(A) Ketoconazole decreases metabolism of terfenadine# Large amounts of Terfenadine reach systemic circulation if erythromycin, ketoconazole, clarithromycin are concurrently administered, as these drugs are P450 enzyme inhibitors.> Azithromycin, fluconazole have no effect & found to be safe.
Pharmacology
Miscellaneous (Pharmacology)
f35fd423-9e89-4e83-a5b2-a3d45ea45ef6
Where is the Cave of Retzius present?
Between urinary bladder and rectum
Between urinary bladder and cervix
In front of the bladder
Between the cervix and the rectum
2c
single
Space of Retzius -        Horseshoe shaped space -        Between the anterolateral pelvic wall and the sides of bladder and prostate.
Anatomy
null
6cb2d3f2-8e2c-4def-a726-30634ab1ad31
Prolonged treatment with INH leads to deficiency of:
Pyridoxine
Thiamine
Pantothenic acid
Niacin
0a
single
Ans. (A) Pyridoxine(Ref: Katzung 11th/e p825, KDT 8th/e p818)Isoniazid can cause peripheral neuropathy due to deficiency of pyridoxine.
Pharmacology
Chemotherapy: General Principles
d4658cbc-2293-4fe2-9f1d-861feda3ae1f
Klebsiella pneumonia is
Lobar pneumonia with absent air bronchogram sign
Involves lower lobe predominantly
Cavitation is common
Pleural effusion is not commonly seen
2c
single
Klebsiella pneumonia : Air bronchogram sign positive. Involves upper lobe. Cavitations and pleural effusion is common.
Medicine
null
f04b2771-384e-4f7b-86be-d673d1e1cf08
For calculation of incidence denominator is taken as -
Mid year population
Population at risk
Total number of cases
Total number of deaths
1b
single
ref: Park&;s 23rd edition pg 60 INCIDENCE= No. of new cases of specific disease during a given time period / population at risk during that period x 1000
Social & Preventive Medicine
Epidemiology
cb8097f1-0612-4ca8-9917-722104cbda1f
Which is NOT an oncogenic virus-
HTLV- 1
Herpes simplex
Papilloma virus
None
3d
multi
Ans. is 'None'
Microbiology
null
7994ea6c-aa3b-4d46-8d5c-021ca843fe94
Most impoant in establishing diagnosis of leprosy is: March 2010
Evidence of neural involvement
Hypopigmented patches
Slit smear for AFB
Positive lepromin test
2c
single
Ans. C: Slit smear for AFB Tissue smear testing/slit-skin smears. An incision is made in the skin, and the scalpel blade is used to obtain fluid from a lesion. The fluid is placed on a glass slide and stained by using the Ziehl-Neelsen acid-fast method or the Fite method to look for organisms. The bacterial index (BI) ...
Skin
null
387767cf-6641-4758-961c-e78eacf4d166
The laser procedure, most often used for treating iris neovascularization is:
Goniophotocoagulation
Laser trabeculoplasty
Panretinal photocoagulation (PRP)
Laser iridoplasty
2c
single
C i.e. Panretinal photocoagulation (PRP)
Ophthalmology
null
487a9f93-70c6-4f51-8864-4b6b1a681e3e
Anterior compament of leg contains all except
Peroneus brevis
Tibialis anterior
External hallucis longus
External digitorum longus
0a
multi
ANTERIOR COMPAMENT:- Muscles:-1. Tibialis anterior 2. Extensor hallucis longus3. Extensor digitorum longus 4. Peroneus teius. Aery: anterior tibial aery. The blood supply of anterior compament is reinforced by the perforating branch of peroneal aery. Nerve:-Deep peroneal nerve. {Reference: BDC 6E vol2 pg 93}
Anatomy
Lower limb
0d2e01e2-13cb-4dcf-b101-c16fd0664e70
All of the following methods are antilarval measures except -
Intermittent irrigation
Paris green
Gambusia affinis
Malathion
3d
multi
Antilarval measures of mosquito control are environmental control- source reduction and minor engineering measures like filling, levelling, intermittent irrigation. chemical control- mineral oils, Paris green, synthetic insecticides (Fenthion, Chlorpyrifos, and Abate). biological control -larvivorous fishes like Gambus...
Social & Preventive Medicine
Environment and health
c396fc9b-70af-4e21-a0b6-f9051923befe
in case of unstable lie of fetus, the placenta is usually:
Cornual
Lateral wall
Fundus
Lower segment
3d
multi
Unstable lie This is a condition where the presentation of the fetus is constantly changed beyond 36th week of pregnancy when it should have been stabiliseed The causes are those which prevent the presenting pa to remain fixed in the lower pole of the uterus that is grand multipara,hhydramnios,contracted pelvis,placent...
Gynaecology & Obstetrics
Abnormal labor
6a9d6141-070f-4d55-8017-a18870ca1e0d
Capsicum seed can be confused with ?
Strychnine
Dhatura
Risinus
Opiun
1b
single
Ans. is 'b' i.e., Dhatura
Forensic Medicine
null
9ea76fc8-ac95-4e35-bd7e-c1a5fca25edb
The ocular basement membrane is stained with
Alcaine blue
Giemsa stain
Methylene blue
Periodic acid-Schiff
3d
single
Not only ocular almost all basement membranes are stained with PAS (Periodic acid-Schiff) Because they have mucopolysaccharides.Periodic acid-Schiff reactive (PAS) method is principally used to demonstrate structures rich in polysaccharides (glycogen), mucopolysaccharides (e.g., ground substance of connective tissues, ...
Pathology
General pathology
08d6cd19-c93f-407a-9d61-2fa8ff70d9f2
Kyasanur Forest Disease (KFD) is transmitted by
Fleas
Mosquitoes
Ticks
Mites
2c
single
KFD is a tick-borne viral hemorrhagic fever endemic to South AsiaThe disease is caused by a virus belonging to family Flaviviridae, which also includes yellow fever and dengue feverThe vector for KFD is Haemophysalis spinigera, a forest tickHumans contract infection from the bite of nymphs of the tickReservoir hosts ar...
Medicine
All India exam
258cff73-e9ff-49fd-b590-f6d6c61b48bd
Hexosaminidase A deficiency causes:
Niemann-pick
Tay-Sachs disease
Hurler syndrome
Gaucher's disease
1b
single
Ans: b. Tay-Sachs disease [Refs Harper 30th/251; Lippincott 6th/212; Harrison 19th/432e,433eHexosaminidase A deficiency is an enzyme deficiency that causes brain and other nerve cells to die, which can lead to severe neurological and mental problems.Hexosaminidase A (HEX A) deficiency is caused by a deficiency in an en...
Biochemistry
null
112b0600-5175-4afe-bcee-f6f0fe8d99cd
Monge's disease refers to:
Primary Familial Polycythemia
High Altitude Erythrocytosis
Spurious Polycythemia
Polycythemia Vera
1b
single
Answer is B (High Altitude Erythrocytosis) lionge's disease (Chronic :Mountain Sickness) is also known as High Altitude Pathologic Erythrocytosis. Chronic Mountain Sickness; Monge's disease; (High Altitude Pathologic Erythrocytosis; High Altitude Excessive Polycythem a) * Excessive Erythrocytosis (Hb>19 /dL for females...
Medicine
null
f11e4916-a8f7-4d3c-865d-cf2d1d8cf673
All are true of police inquest, except:
Senior head constable can investigate
Most common inquest
Panchnama has to be signed by IO
IO cannot summon
3d
multi
Police inquest is held by a police officer (Investigation Officer--IO) not below the rank of senior head constable in all cases of unnatural deaths with the exceptions mentioned under Magistrate inquest. Police inquest (174 CrPC) : Most common type of inquest. Minimum cadre of police for conducting inquest is station o...
Forensic Medicine
FMT Q Bank
9c1f703b-cdad-48ed-af7c-d2daab2a1fc7
Following drugs act against HIV–2 Except :
Ritonavir
Tenofovir
Efavirenz
Zalcitabine
2c
multi
null
Pharmacology
null
a4668f83-200f-4fb8-aa4f-0b3b5e0aa7e3
Vidian Neurectomy is indicated in
Glossophayngeal neuralgia
Trigeminal neuralgia
Vasomotor rhinits
Atrophic rhinits
2c
single
Vasomotor rhinitis: increased parasympathetic discharge Vidian neurectomy is done. Ref : SRB&;s 4thE
Surgery
Trauma
8e3b5309-7b30-4083-816b-c20bc268fd57
Precocious puberty in girls is defined by the onset of secondary sexual characteristic before the age of
5 years
7 years
8 years
9 years
2c
single
Precocious puberty : Onset of secondary sexual characteristic before the age of 8 years in girls and 9 years in boys.
Pediatrics
null
20c8c878-2096-49cb-ae7f-dc88dd9df786
Trismus in CA of temporal bone occurs due to involvement of-
Dura
Temporo mandibular joint
Mastoid
Eustachian tube
1b
single
Ans. is 'b' i.e., Temporo mandibular joint Clinical Assessment of Temporal bone Tumorso A long history of ear discharge suggests cancer associated with inflammatory ear disease (Maijolins ulcer)o Pulsatile tinnitus suggests tumor of vascular origin such as glomus tumor or a middle ear vascular anamoly; or a duralarteri...
ENT
Oral Cavity
0c49c311-b16c-4e0a-a7b9-5706beb6295d
Which is the wrong statement regarding hepatitis viruses?
Hepatitis A & E are enveloped viruses
Hepatitis D are circular RNA virus
Hepatitis C & E contains linear RNA virus
No vaccine is available for hepatitis C virus
0a
multi
Hepatitis A & E are non enveloped virus Hepatitis B is the only DNA virus Hepatitis B & D have a circular genome ref - davidsons medicine 23e pg872-875
Medicine
Nutrition
39c543dc-ce59-414b-9cd1-29bee8818dbc
The earliest morphological evidence of ovulation on endometrial biopsy is:
Pseudostratification
Basal vacuolation
Decrease in glycogen content
Predecidual reaction
1b
single
Endometrial biopsy was used in the past to find out whether the female has ovulated or not. Nowadays USG follicular monitoring is being done Subnuclear basal vacuolation is characterized by glandular growth and presence of vacuoles due to secretion of glycogen between nuclei and basement membrane. It is due to the effe...
Gynaecology & Obstetrics
null
fd41c473-b47c-4045-bc53-a0212b779317
What is the test being done & what sign is it used to demonstrate?
Scraping test, Auspitz sign
Grattage test, Koebner's phenomenon
Scrapping test, Koebner's phenomenon
Grattage test, Auspitz sign
3d
single
Auspitz sign is characterized by:- a) Micaceous silvery white scales b) Burkley membrane c) Pin point bleeding This is seen in psoriasis & demonstrated by grattage test. Auspitz sign is presence of pinpoint bleeding at the base of a plaque after scale is forcibly removed in patients with psoriasis. The successive remov...
Dental
Psoriasis
84564aa0-85cf-41f5-92cb-26cfbdef6777
Transverse myelitis usually presents
1 – 2 weeks
1 – 2 months
4 – 6 months
1 year
3d
multi
Usual time of onset of symptoms of post-radiation transverse myelitis is 12-24 months but can occur as early as 6 months after radiation.
Radiology
null
b8e3b2be-89ac-478d-a394-4e528b8def94
Positive nitrogen balance is seen in-
Starvation
Extreme weight loss
During fever
Recovery phase of protein deficiency
3d
single
Ans. is 'd' i.e., Recovery phase of protein deficiency Nitrogen Balance* Because nitrogen is excreted as proteins are recycled or used, we can use the nitrogen in body to evaluate whether the body is getting enough protein.* To estimate the balance of nitrogen, and therefore the protein in body, nitrogen intake is comp...
Medicine
Nutrition
ba165b83-fcc9-4933-b981-f8a6f29b874e
True regarding electrophoresis are all except
Isoelectric focusing use ampholytes & pI
Adversely affect structure & function
Depends on size not on shape
Commonest method of purifying protein
2c
multi
Electrophoresis depends on size as well as on shape Electrophoresis is the process that uses an electric field to drive the movement of charged particles. Electrophoresis depends on the net charge of the particle, molecular weight, pH of the medium, the strength of the electric field and temperature. About other optio...
Biochemistry
null
8ca2891a-ba0f-434a-b9f6-071529cb6885
Asthenospermia means:
Immotile sperms
Absent sperms
Dead sperms
Dysmorphic sperms
0a
single
Ans: A (Immotile sperms) Ref: Harrison's 18th edn.Explanation:Azoospermia - Absence of sperm in the ejaculate.Aspermia - Zero volume ejaculate.Oligospermia - Low numbers of sperm.Asthenospermia - Poor sperm motility.Teratospermia - Abnormal morphology (shape) of sperm.
Medicine
Gynae & OBS
4f896369-a8ab-4770-8bd8-62a456719d4b
Which of the following increases BMR?
Starvation
Obesity
Ingestion of food
Sleep
2c
single
Factors that influence basal metabolic rate are: Body size: Metabolic rate increases as weight, height, and surface area increase. Body composition: Fat tissue has a lower metabolic activity than muscle tissue. As lean muscle mass increases, metabolic rate increases. Gender: The basal metabolic rate (BMR) averages 5 to...
Physiology
Endocrinology
bc24d9f3-f9ce-4b86-aaad-7295d62c7082
Which of the following is relatively difficult tooth to extract
Maxillary canine
Maxillary central incisor
Mandibular premolar
Mandibular canine
0a
single
null
Surgery
null
a17e0a12-f553-4be2-bd2e-6873b37e98b8
Gold standard investigation for screening of breast carcinoma in patients with breast implant
MRI
USG
Mammography
CT- Scan
0a
single
MRI Indicated in scarred breast, implants and borderline lesions for breast conservation Investigation of choice for implant related complications Gold standard for imaging breast in females with implants Ref: Sabiston 20th edition pgno: 826-828
Anatomy
Endocrinology and breast
06c90691-ce04-42e4-a7da-ac5d629a6f4c
Which of the following drug can produce Dramatic improvement in patients with type 2 Lepra reaction
Thalidomide
Steroids
Dapsone
Clofazimine
0a
single
Refer KDT 6/e Pg 756 Steroids are drug of choice for both type 1 as well as type 2 Lepra reaction Thalidomide us used in steroid resistant type 2 Lepra reaction
Pharmacology
Chemotherapy
d91e11aa-1b50-4a33-9bb5-73fe4271e190
Which of the following colonic polyps has no risk far malignancy
Juvenile polyps
Hamaomatous polyps associated with Peutzjegher's syndrome
Juvenile polyposis syndrome
Familial adenomatous polyposis syndrome
0a
single
.Juvenile Polyps * Commonest polyp of colorectum in infants and children. * Can cause intussusception, prolapse through rectum, bleeding.* Colonoscopic polypectomy is done. * Not a pre-malignant condition. PEUTZ-JEGHER'S POLYP is common in small intestine (jejunum) * Features are multiple, familial, hamaomatous intesti...
Surgery
G.I.T
401d7a95-fd66-44c9-a63d-807d9874751d
Aldosterone is known to cause sodium retention. Its Na+ retaining action is exeed on which pa of the nephron?
Proximal convoluted tubule
Ascending limb of loop of Henle
Collecting ducts
Early distal convoluted tubule
2c
single
* Aldosterone is the principal mineralocoicoid. It stimulates the reabsorption of Na+ and excretion of K+ and H+ by its action on late distal tubules and collecting ducts.
Pharmacology
Adrenal
aaad5cfd-46f8-4e33-b589-7c70c8f78958
A woman of 45, a known cause of pemphigus vulgaris on a regular treatment with controlled primary disease presented with pain in the right hip and knee. Examination revealed no limb length discrepancy but the patient has tenderness in the scarpa's triangle and limitation of abduction and internal rotation of the right ...
Stress fracture of neck of femur
Avascular necrosis of femoral head
Perthe's disease
Transient synovitis of hip
1b
single
This patient has Pemphigus vulgaris taking treatment (steroid is the DOC). Pain in hip and knee (Pain of hip can refer to hip). Limitation of abduction & internal rotation. Diagnosis is AVN of hip.
Orthopaedics
null
e7a856a0-e8a2-4dc1-8ca6-9343d491b034
Monro-Kellie doctrine is related to injury of
Head
Abdomen
Chest
Leg
0a
single
An increase in volume of any one of rhe three components brain,blood, CSF must be at the expense of other two Brain is least compressible among the three Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:813,814,815
Physiology
General physiology
c061ee25-c8e1-44d0-ad47-51cfef2f6e39
Kveim Slitzbach test is useful in the diagnosis of
Tuberculosis
Sarcoidosis
Leprosy
Cat scratch disease
1b
single
null
Pathology
null
72d90c63-5e0d-4735-a452-d6be4b5efce1
Diversion of urinary bladder is best done at :
Jejunum
Ileum
Cecum
Colon
1b
single
Ileal segment is the best for urinary diversion after cystectomy. Still better method is "Continent cutaneous diversion" method. But the best method is "Orthotopic neobladders". "Incontinent cutaneous urinary diversion" by ileal conduit: a segment of ileum is exteriorized in the form of a stoma through the abdominal wa...
Surgery
null
b3f58f90-3133-4568-9211-34a42a741789
An 18-year-old woman presents with abdominal pain localized to the right lower quadrant, nausea and vomiting, mild fever, and an elevation of the peripheral leukocyte count to 17,000/uL. Examination of the surgically resected appendix is most likely to reveal
An appendix with a normal appearance
Neutrophils within the muscular wall
Lymphoid hyperplasia and multinucleated giant cells within the muscular wall
A dilated lumen filled with mucus
1b
multi
Acute appendicitis, a disease found predominantly in adolescents and young adults, is characterized histologically by acute inflammatory cells (neutrophils) within the mucosa and muscular wall. Clinically, acute appendicitis causes right lower quadrant pain, nausea, vomiting, a mild fever, and a leukocytosis in the per...
Pathology
miscellaneous
20b599b2-2dc7-4675-98f2-92174ed2aaa2
A 40 year old woman is being evaluated. She is noted to have a decreased latency of REM. Which disorder is this woman most likely to be suffering from?
Schizophrenia
Major depression
PTSD
Obsessive-compulsive disorder
1b
single
Ans. B. Major depressionA decreased latency of REM sleep is seen in major depression. Depression is the psychiatric disorder that has been most associated with disruptions in biological rhythms. Besides the decreased latency of REM sleep, one can find early morning awakening and other neuroendocrine perturbations.
Psychiatry
Mood Disorders
e22dea82-9f84-4355-bcc1-e44a1749c4ef
Hypersensitivity is seen with following medicament?
CHX
Povidone iodine
Oxygenated water
Peroxide (H2O2)
0a
single
null
Dental
null
cb6fb480-a4a6-4627-b338-8d763f427505
Reactivation tuberculosis and primary squamous cell carcinoma of the lung are similar in that they both are commonly associated with:
Cavitation
Scar carcinomas
Silicosis
Ectopic secretion of a parathormone-like peptide
0a
multi
Both reactivation tuberculosis (TB) and primary squa­mous-cell carcinoma of the lung are associated with cavitation. Other pulmonary diseases associated with cavitation include systemic fungal infections, Klebsiella pneumonias, and silicosis. In silicosis, the large fibrotic nodules undergo central necrosis from ischem...
Unknown
null
2ba0b7dd-9892-4316-a7dc-5b7cb8a3f8c9
Giant hypertrophy of gastric mucosa similar to brain surface is seen in -
Peptic ulceration
Carcinoma stomach
Menetrier's disease
Liomyosarcoma
2c
single
Menetrier disease  It is characterized by giant cerebriform (similar to brain surface) enlargement of rugal folds of gastric mucosa. Enlargement of rugal folds is due to profound hyperplasia of surface mucous cells → gastric secretion & contain excessive mucus. There is accompanying glandular atrophy → gastric disease...
Pathology
null
0bb6f41a-830b-4db7-82fa-54bf582d6d54
In PCOD which of the following drug is not used for infertility
Clomiphene
Tamoxifen
Spironolactone
Testosterone
2c
single
Clomiphene citrate:  Used for induction of ovulation; can be 50 mg/day increased to 150mg/day; Starting from day 2 to day 6 of the cycle for 5 days Tamoxifen 10 mg daily for 6 months has been effective in treating male infertility Testosterone 25 -50 mg daily orally improves testicular functions Spironolactone is an ...
Gynaecology & Obstetrics
null
26f14f3e-6623-49c8-8525-7d285105dfd0
Major form of folic acid to transfer one carbon is -
Methylene THF
Formyl THF
Methyl THF
All
0a
multi
Ans. is 'a' i.e.. Methylene THFFolic acido The active form of folic acid (pteroyl glutamate) is tetrahydrofolate (THF).o THF serves as a carrier of one-carbon (C1) unitQ during several biosynthetic reactions like nucleic acidQ and amino acid metabolism.o Two other cofactors are also known to be involved in the addition...
Biochemistry
Vitamins
00e5f19a-b3e1-4d49-9468-d30ea7aba357
Spinal epidural space contains
Areolar tissue and internal veebral venous plex uses
Only areolar tissue
Only cerebrospinal fluid
Veebral venous plexus and cerebrospinal fluid
0a
single
Epidural space This is the interval which seperates the periosteum in the veebral canal from the spinal duramater.The space is filled with loose areolar tissue,semiliquid fat,a network of veins,and the small aeries which supply the structures in the veebral canal. REF.CUNNINGHAM'S MANUAL OF PRACTICAL ANATOMY,Vol.3,PG.1...
Anatomy
Thorax
7e8c04d4-450b-4917-8d86-920ed217dd16
Brachytherapy is the internal radiation therapy procedure for treating tumors. All are used in brachytherapy, EXCEPT:
I 125
I 131
Cs 137
Iridium 192
1b
multi
Clinically used isotopes in brachytherapy include iridium 192 (192 Ir), iodine 125 (125 I), cobalt 60 (60 Co), cesium 137 (137 Cs), gold 198 (198 Au), and palladium 103 (103 Pd). Iodine 131 is not used in brachytherapy. Ref: Nuclear Development Beneficial Uses and Production of Isotopes 2004 Update ... By OECD, Nuclear...
Radiology
null
a09a5e23-152d-41c9-8a8d-f94509bf59ce
Which one of the following is not a feature of liver histology in non-cirrhotic poal fibrosis (NCPF)?
Fibrosis in and around the poal tracts
Thrombosis of the medium and small poal vein branches
Non-specific inflammatory cell infiltrates in the poal tracts
Bridging fibrosis
3d
multi
Ans. is 'd' i.e., Bridging fibrosis
Pathology
null
42632552-2564-447a-964b-803a592b6bb1
Derelation & depersonalisation seen in which type of disorder ?
Dissociative disorder
Personality disorders
Mania
None
0a
multi
Ans. A. Dissociative disorder
Psychiatry
null
03676389-e816-4895-bfc2-6408c588d1ed
Nerve involved in Arcade of Frohse ?
Median
Ulnar
PIN
Radial
2c
single
Ans. is 'c' i.e., PIN
Surgery
null
d1735984-db7a-4f1f-b196-357960ebd4ea
The primary respiratory regulatory centre is located at
Dorsal medulla
Aponeurotic centre
Pneumotaxic center
Ventral medulla
0a
single
The respiratory centers are located in the medulla oblongata and pons, which are pas of the brainstem. The respiratory centers are divided into four major groups, two groups in the medulla and two in the pons. The two groups in the medulla are the dorsal respiratory group and the ventral respiratory group. The two grou...
Physiology
Nervous system
2861342b-131c-4b4d-ab50-c69190c2bcc8
In cases of burn, which is the fluid of choice in first 24 hours?
Ringer Lactate
Normal saline
5% Dextrose
Blood
0a
single
Ans is 'a' i.e. Ringer lactate
Surgery
null
d3a8c27b-1380-478f-82c3-cb1c9acde99f
A surgeon was doing a laparoscopic hernia surgery and he visualised the triangle of doom. Which of the following is not the boundary of the same
Vas deferens
Gonadal vessels
Reflected peritoneum
Inguinal ligament
3d
single
The preperitoneal anatomy seen in laparoscopic hernia repair led to characterization of impoant anatomic areas of interest, known as the triangle of doom, the triangle of pain, and the circle of death. The triangle of doom is bordered medially by the vas deferens and laterally by the vessels of the spermatic cord. The ...
Anatomy
Urology
c438c1e4-5cdc-49ce-8f29-dc1518639d3c
Which of the following are histopathological features of Extra hepatic Biliary Atresia -
Bile lakes
Hepatocyte ballooning degeneration
Marked bile duct proliferation
All
2c
multi
(c) Marked Bile duct proliferation
Surgery
null
3c9d9f65-eecf-4d89-8883-fd1648e77026
Drug emerging as the agent of choice for initial treatment of tourette syndrome -
Haleperidol
Valproate
B complex
Clonidine
3d
single
Ans. is 'd' i.e., ClonidineTounette syndromeo Mild and non disbling-Education and counselling without pharmacological tic suppression therapyo With bothersome Tics-Tetrabenzineo Only focal or vocal motor Tics-Botulinum toxin injection into the affected muscleso With ADHD-Guanafacine or clonidine
Medicine
Drugs (C.N.S.)
53f1fa23-266f-4aaa-9177-e34e77f7bb6c
What is NOT a feature of Sturge Weber syndrome :
Rail track appearance
Herniatrophy of the brain
Convulsion
Empty sella
3d
single
Answer is D (Empty sella): The clinical hallmark in the form of convulsions, Rail road tract appearance on X-ray and unilateral coical atrophy (hemiatrophy) on CT scan are diagnosis of Sturge-Weber syndrome. Sturge weber syndrome It results from the anomalous development of primordial vascular bed during early stages o...
Medicine
null
a9a267a2-47b2-4ede-aa64-a703c8ffdff8
Dark field microscopy used in ?
Vibrio
Syphilis
TB
Brucellosis
1b
single
Ans. is 'b' i.e., Syphilis Dark field microscopy is used for spirochetes (for example T pallidum which causes syphilis). Dark ground/ Dark field microscope Very slender organisms such as spirochetes and filamentous organs such as flagella are not visible under ordinary illumination. The contrast in dark field microscop...
Microbiology
null