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135
e78357f9-2c9a-4264-b7f8-553a446fe9b7
A 25-year old patient with a history of recent respiratory tract infection complains of severe chest pain at rest. The ECG of the patient is given. The most probable diagnosis of the patient is?
Acute MI
Prinzmetal angina
Takotsubo cardiomyopathy
Acute pericarditis
3d
single
The history points to a recent viral infection that could contribute to the development of pericarditis. Acute Pericarditis -Most common cause of pericarditis is idiopathic or viral. -ECG findings: Hea rate= 75 bpm Axis= normal PR interval= 0.16 sec QRS= 0.08 sec QT= 400 msec Uniform ST segment elevation - Concave upwa...
Medicine
Acute coronary syndrome
f93516e5-a707-4dfe-9086-62b143d046e5
Which vein is preferable for coronary by pass grafting-
Saphenous vein
Short saphenous vein
Epigastric vessels
Radial artery
0a
single
Ans. is 'a' i.e., Saphenous vein o Most common conduits used is greater saphenous vein. Ideal characteristics of a saphenous vein conduit are that it should be atleast having diameter of 3.5 mm and free from any varicosity or areas of structure,o If the saphenous vein is inadequate or unavailable^ short saphenous vein ...
Surgery
Thorax
b5b1a839-9b0c-4f59-9364-efd0d4c6845d
Hyperplastic arteriolitis with necrotizing arteriolitis is seen in?
Wegner’s granulomatosis
Malignant hypertension
Buerger’s disease
Benign hypertension
1b
single
Hyperplastic arteriolosclerosis is more typical of severe hypertension. Vessels exhibit "onion skin" ."concentric, laminated thickening of arteriolar walls and luminal narrowing . The lamination consists of smooth muscle cells and thickened , re duplicated basement membrane . In malignant hypertension these changes are...
Pathology
null
0bf248f5-9706-4b4f-8d06-5b70a89a95e3
All of the following, statements ubout Digoxin induced arrhythmias are true, Except -
Biventricular Tachycardia
Paroxysmal Atrial Tachycardia with variable AV Book
Ventricular Bigeminy
May be used to Atrial Fibrillation
0a
multi
Digoxin remains one of the most frequently prescribed drugs in the management of atrial fibrillation. The main indications for digoxin in atrial fibrillation are restoration of sinus rhythm, prevention of recurrence and slowing of the ventricular rate Other common dysrhythmias associated with digoxin toxicity include: ...
Medicine
C.V.S
3b5cfa66-9f1c-478f-bbcc-d819035744c8
Which of the following is the most useful investigation for thyroid function: September 2011
T3
T4
TSH
TRH
2c
single
Ans. C: TSH TSH is usually regarded as the most useful investigation of thyroid function Thyroid pathology: Primary hypehyroidism: - Decreased TSH - Raised T4 Secondary hypehyroidism: Raised TSH Hypothyroidism: Raised TSH
Surgery
null
513e714f-6132-48a6-ac78-5bf3eb9d1fac
What is the indication of using systemic steroids in a case of rheumatoid arthritis -
Carpal tunnel syndrome
Presence of deformities
Mononeuritis multiplex
Involvement of articular cartilage
2c
multi
null
Medicine
null
6840b7b5-f280-4252-87b2-2592cffd7e16
LMW heparin is preferred over unfractionated heparin because:
LMW heparin directly inhibit thrombin whereas unfractionated heparin acts activation of anti thrombin
LMW heparins have higher risk of causing bleeding
LMW heparin can be given subcutaneously as well as orally
LMW heparin has consistent bioavailability.
3d
multi
LMW heparin inhibit factor Xa only and have a weak effect on thrombin , aPTT, or CT are not prolonged. Heparin acts by activation of antithrombin III. LMW heparin is given subcutaneosly due to better bioavalability.LMW heparin have subcutaneous bioavalability of 70 - 90%. From medical pharmacology padmaja 4th edition P...
Pharmacology
Hematology
33113d21-1576-4289-be05-3fe2c9f5e224
In TCA cycle of tricarboxylic acid, which is first formed
Isocitrate
Citrate
Succinate
Fumarate
1b
single
B i.e. Citrate
Biochemistry
null
c0180a23-75b0-40f5-9e26-a6cd13a380df
Salt loosing nephritis is due to
Lupus nephritis
Streptococcal infection
Interstitial nephritis
Goodpasteures syndrome
2c
single
Salt-losing nephritis is one of many clinical situations involving electrolyte disturbance in renal disease. This type of nephropathy is characterized by hyponatremia and hypochloremia, lassitude, thirst, polyuria, azotemia, and circulatory collapse. Interstitial nephritis is a kidney disorder in which the spaces betwe...
Pathology
Urinary tract
51f6ee67-b6e2-4709-8b38-20e6f34ab16a
Adrenaline, noradrenaline and dopamine act through?
Two pass receptor
Ligand gated channel
Seven pass receptor
One pass receptor
2c
single
Ans is 'c' i.e. Seven pass receptor o Adrenergic receptors (Adrenaline, noradrenaline) and dopamine receptors are G-protein coupled receptors which are heptahelical receptors, i.e., have seven transmembrane spanning segments (Seven pass receptors)
Pharmacology
null
de4448f4-2e41-4529-bb50-fa09c5101898
In random sampling, the chance of being picked up is -
Same and known
Not same and not known
Same and not known
Not same but known
0a
single
null
Social & Preventive Medicine
null
11a944e7-f256-4d11-8ec3-5819b417685d
Renauld Braud phenomenon is seen in
Candida albicans
Candida psittaci
Histoplasma
Cryptococcus
0a
single
Candida albicans has the ability to form germ tubes within 2hours when incubated in human serum at 37C - Reynolds-Braude phenomenon. Ref: Textbook of Microbiology, Ananthanarayan and Paniker; 9th edition
Microbiology
mycology
d922e5c1-038e-4607-a2ee-1d8f525e921d
Pseudolymphoma occurs because of long term use of :
Carbamazepine
Phenobarbital
Phenytoin
Primidone
2c
single
Side effects of phenytoin Gingival hyperplasia Lymphadenopathy Hirsutism Osteomalacia Facial coarsening Skin rash
Pharmacology
Epilepsy
1fa33af6-b952-47a5-aab8-d9d92590681a
Dimension of HDI which is measured to check good standard of living ?
Income
Knowledge
Lingevity
Housing
0a
single
Ans. is 'a' i.e., Income HDI is a composite index combining indicators representing three dimensions ? Longevity (life expectancy at bih) Knowledge (Adult literacy rate and mean years of schooling, i.e. Gross enrolement ratio) Income (real GDP per capita in purchasing power parity in US dollars) Among these three, inco...
Social & Preventive Medicine
null
1537d19c-47b3-4a9a-a28e-a5b70a2f29f9
Nerve supply of trapezius is by
Axillary
Musculocutaneous
Median
Spinal accessory nerve
3d
single
the and sternocleidomastoid are supplied by spinal accessory nerve. Both of them develop from brachial arch mesoderm. The principal action of trapezius is to rotate scapula during abduction of arm beyond 90deg. Clinically the muscle is tested by asking the patient to shrug his shoulder against resistance. REF: BD Chaur...
Anatomy
Upper limb
4ca78873-3cd6-4197-bfa2-32bce74538c5
Which of the following structure is not a primary suppo of uterus?
Pelvic diaphragm
Uterosacral ligament
Transverse cervical ligament
Broad ligament
3d
single
Broad ligament is a secondary suppo of uterus. Structures forming primary suppo to the uterus are pelvic diaphragm, perineal body, urogenital diaphragm, uterine axis, pubocervical ligament, transverse cervical ligament, uterosacral ligament and round ligament of uterus.
Anatomy
null
a01afbde-879d-4cee-9de8-8305c8c1397e
Which of the following drug used in treating leprosy acts as a bactericidal agent?
Clofazimine
Dapsone
Rifampicin
Ethionamide
2c
single
Dapsone, rifampicin and clofazimine are WHO recommended drugs used in the treatment of leprosy. Among these only rifampicin is bactericidal. Rifampin binds to the beta subunit of bacterial DNA-dependent RNA polymerase and thereby inhibits RNA synthesis. It is bactericidal, it penetrates most tissues and into phagocytic...
Pharmacology
null
43cfb3cb-6fb9-41da-8ccf-e3b23f828394
Epley's maneuver is used in the treatment of
Positional veigo
Otosclerosis
ASOM
CSOM
0a
single
Epley`s maneuver is used in the treatment of Positional Veigo (BPPV)Dix Hallpike`s test is the diagnostic testOther exercises are: Semont`s maneuver, Brandt Darrof exercisesSurgeries: Singular neurectomy, Posterior canal occlusion, Labyrinthectomy, Vestibular nerve sectionRef: Hazarika; 3rd edition; Page no: 108
ENT
Ear
972d4acd-cc5d-4baf-baf1-d7e60531d009
Bacitracin acts on :
Cell wall
Cell membrane
Nucleic acid
Ribosome
0a
multi
Bacitracin acts by inhibiting the synthesis of the cell wall. Other polypeptide antibiotics like polymyxin B, colistin and tyrothricin act by an affecting membrane.
Pharmacology
null
be7b76fd-89d8-479e-9ba5-8b1d862534fe
Which of the following is false about starvation ketoacidosis?
Metabolic acidosis
Smell of acetone in breath
Benedict's test +ve
Rothera's test +ve
2c
multi
null
Biochemistry
null
158a3ed4-8496-4ab2-aad6-2f115d37680c
Spinal epidural space is the largest at the level of the
12th thoracic veebra
1st lumbar veebra
2nd lumbar veebra
3rd lumbar veebra
3d
single
Spinal epidural space is largest at 3rd lumbar veebrae .Spinal epidural space is a closed anatomic space between the dura mater and the bony spinal canal. It extends from the foramen magnum to the sacrum. Unlike its intracranial counterpa, spinal epidural space is real. The presence of anchoring plicae and meningoveebr...
Anatomy
Thorax
258cec82-51fe-4888-a33d-5c08c7587e78
Cyclosporine enlargement of gingiva can be classified as:
Non inflammatory
Inflammatory
Developmental
Malignant
0a
single
null
Dental
null
5dea3bcb-3e4f-4d6d-81ae-52cd81542e35
Which cell does not NOT differentiate in bone marrow?
B lymphocyte
T lymphocyte
Neutrophil
Basophil
1b
single
Bone marrow provides the environment for development of precursor cells into erythrocytes, platelets, granulocytes, monocytes, and B lymphocytes. Although it is likely that T lymphocytes progenitor cells also arise in bone marrow, differentiation and programming of new T lymphocytes occurs in the thymus. Ref: Levinson ...
Microbiology
null
2f9356ad-4194-40b2-92b1-e181e1e249b5
Which of the following is not true about medullary thyroid carcinoma?
Are a type of neuroendocrine tumors
Associated with MEN 2A and 2B syndrome
Form about 25% of the thyroid malignancies
Tumor cells may secrete serotonin, ACTH and VIP
2c
multi
Ans. is 'c' i.e., Form about 25% of the thyroid malignancies Medullary carcinoma of thyroid* Medullary carcinomas of the thyroid are neuroendocrine neoplasms derived from the parafollicular cells, or C cells, of the thyroid, and account for approximately 5% of thyroid neoplasms.* Medullary carcinomas, similar to normal...
Surgery
Thyroid Gland
c6a5b265-7cbc-47eb-b938-26c7c3dc3ff6
Which drug has inverse agonist activity at benzodiazepine receptors?
Flumazenil
Beta carboline
Naltrexone
Zopiclone
1b
single
Benzodiazepine Binding Site Ligands: The components of the GABA A receptor-chloride ion channel macromolecule that function as benzodiazepine binding sites exhibit heterogeneity. Three types of ligand-benzodiazepine receptor interactions have been repoed: Agonists: facilitate GABA actions, and this occurs at multiple B...
Pharmacology
JIPMER 2017
8e32a34c-1f6e-447a-a2e0-502aa55d49e6
Most common lesion in diabetic nephropathy
fibrin caps
Capsular drops
Diffuse glomerulosclerosis
Kimmelstiel Wilson nodule
2c
single
m/c - Diffuse glomerulosclerosis  Pathognomonic - Kimmelstiel Wilson nodule
Medicine
null
0d1b9517-c7bf-40df-97a6-2888a9aa4ec5
A thirty one year old male with neprhrotic syndrome complains of pain in right hip joint of 2 months duration. The movements at the hip are free but painful terminally. The most likely diagnosis is -
Tuberculosis of hip
Avascular necrosis of femoral head
Chondrolysis of hip
Pathological fracture of femoral neck
1b
multi
This patient has : -  Nephrotic syndrome (must be taking steroids) Pain in hip Terminal restriction of movements (in AVN, initially movements are restricted terminally only). The diagnosis is AVN of Hip. In all other three options movements of hip are grossly restricted (not terminally).
Orthopaedics
null
dc0dd74f-7dde-4d16-9383-5fb31407b8bc
A 35-year-old woman presents with infertility and palpable pelvic mass. Her CA-125 level is 90 rnIU/mL diagnosis is:
Ovarian Ca
Endometrioma
Tuberculosis
Borderline ovarian tumor
1b
single
In this question we have insufficient information to make any definite diagnosis. At the best we can try to make the most probable diagnosis. CA-125 • This is a non-specific tumor marker • CA-125 is a glycoprotein which is normally not produced by ovarian epithelium but may be produced by both malignant and benign epit...
Gynaecology & Obstetrics
null
fb222ec0-6af8-4c23-91b6-aded4a48981b
True regarding surface anatomy of internal jugularvein -
Line passing from ear lobule to mid pt of clavicle
Line passing from ear lobule to medial end of clavicle
Line joining ear lobule to lateral end of clavicle
Line joining mastoid process to mid pt of clavicle
1b
multi
Ans 'b' i.e., Line passing from ear lobule to medial end of clavicle SURFACE MARKINGS OF IMPORL4N VESSELS OF NECKSurface anatomy of internal jugular vein:o Internal jugular vein is marked by a line joining a point on the neck, medial to the ear lobule to a point at the medial end of the clavicle.Surface anatomy of the ...
Anatomy
Triangles of Neck
0d417fac-84a6-4f45-8a56-d4cb3e8e79ac
Pyruvate dehydrogenase contains all except -
Biotin
NAD
FAD
CoA
0a
multi
A i.e. BiotinPyruvate, the end product of aerobic glycolysis is transpoed into mitochondria by specific pyruvate transpoer, where it is conveed to acetyl CoA by pyruvate dehydrogenase (PDH) complexQ.
Biochemistry
null
b8348fed-8422-4b00-99e0-99031111e7be
Pleomorphism is most commonly seen in:
Anaerobic staphylococci
H. influenzae
Corynebacterium diphtheria
Brucella abous
1b
single
H. influenzae
Microbiology
null
73edbb6d-6f04-4110-be92-df8368997dcd
Drugs causing macular toxicity when given intiavitreally-
Gentamycin
Vancomycin
Dexamethasone
Ceftazidime
0a
multi
Ref:comprehensive ophthalmology AK Khurana 4th edition page no :152 Gentamycin is 4 times more retinotoxic (causes macular infarction) than amikacin. Preferably the aminoglycosides should be avoided. 
Ophthalmology
Vitreous and retina
94d4df55-9bcb-49ae-9d8c-13881bb52f8f
Shortest acting benzodiazepine is :
Midazolam
Alprazolam
Lorazepam
Diazepam
0a
single
null
Pharmacology
null
82abafc3-ceca-41a9-84b9-4fdb2c2ec29e
The recently approved antiepileptic drug lacosamide acts by:
Inhibiting synaptic vesicular protein
Inhibing CRMP protine
Inhibing GABA metabolism
Inhibing glutamate release
1b
single
(Ref: Katzung, 14th ed. pg. 417)* CRMP is Collapsing Response Mediator Protein, which causes neuronal excitotoxicity by releasing BDNF (Brain Derived Neurotropic Factor).* The drug Lacosamide acts by inhibiting CRMP protein, thereby causing protective action against neuronal excitotoxicity.
Pharmacology
C.N.S
443372cc-b626-4bbe-bd13-7ab9d8830ae0
Radioisotopes used in Myocardial perfusion imaging: Thallium 201 18 FDG PET Tc-99m Sestamibi Tc-99m Pyrophosphate Tetrafosmin N-13 Ammonium
1,3,4,5
1,2,3,4,5,6
1,3,5,6
1,3,4,5,6
1b
multi
- Thallium-201, Sestamibi, Tetrofosmin scan are used for Myocardial Perfusion Imaging. - Pyrophosphate scan for Myocardial Infarction. - 18 FDG PET is used to detect Myocardial Viability - N-13ammoniaPETmyocardial perfusion imaging(MPI) yields larger stressperfusiondefects than dipyridamole stress and might reflect the...
Radiology
Nuclear medicine
42f1c17a-65ee-4b24-b0f4-83786c2c1052
Sensitivity of chemoreceptors in COPD
Decreased to H+
Increased to H+
Increased to PCO2
Increased to PO2
2c
single
The main chemoreceptors involved in respiratory feedback are: Central chemoreceptors: These are located on the ventrolateral surface of medulla oblongata and detect changes in the pH of spinal fluid. They can be desensitized over time from chronic hypoxia (oxygen deficiency) and increased carbon dioxide Ref: guyton and...
Physiology
Respiratory system
bf82c509-b54f-40bb-83f3-bdb14fd3e630
Which of the following is the most impoant neurotransmitter deficient in the coex of patients with Alzheimer's Disease
Acetylcholine
Serotonin
Dopamine
Noradrenaline
0a
single
Answer is A (Acetylcholine):The most impoant biochemical abnormality in Alzheimer's disease is the decrease in coical levels of AcetylcholineBiochemically Alzheimer's disease is associated with a decrease in the coical levels of several proteins and neurotransmitters especially acetylcholine, its synthetic enzyme choli...
Psychiatry
null
f9dfa1fb-b5ae-4cdf-92ae-fe36e623bf19
The most useful incision in the operating room for patients with penetrating pericardium injury is
Left anterior thoracotomy
Right anterior thoracotomy
Subxyphoid
Median sternotomy
3d
single
The subxiphoid incision is useful for determining if there is blood in the pericardium and if there is an intracardiac injury; however, exposure is extremely limited, and definitive repair can rarely be performed through the incision. Left (or right) anterior thoracotomy is easily performed, especially in the emergency...
Surgery
Cardio thoracic surgery
7c74aa83-8596-47c8-8fbe-552532f10f07
Which of the following organisms is visualized by gram staining:
Treponema
Borrelia
Mycoplasma
Mycobacterium
1b
single
Ans: b (Borrelia)Ref: Ananthanarayan and Paniker's Textbook of Microbiology, 8th ed.* Treponema - do not stain by ordinary method. Prolonged Giemsa, Fontana or Levaditis method is used* Mycoplasma - has no cell wall. So they are gram negative but are better stained by Giemsa* Mycobacterium-resist decolonisation by alco...
Microbiology
Spirochetes
79fb77c8-9330-4e98-b1ce-27ee744ac4d8
Deficiency of the following vitamin is most commonly seen in sho bowel syndrome ileal resection
Vitamin B12
Vitamin B1
Folic Acid
Vitamin K
0a
single
If the distal 2/3rd of the ileum is including the ileocecal valve is resected, significant abnormalities of absorption of bike salts and Vitamin B12 may occur resulting in diarrhoea and anaemia. These abnormalities occur even though only 25% of total length of the small bowel is removed Proximal bowel resection is bett...
Anatomy
G.I.T
d20086f4-98f6-4a50-a89b-5a304f13a313
The water powder ratio of alginate is:
100 ml of water to 60 gms of powder
40 ml of water to 40 gms of powder
40 ml of water to 15 gms of powder
15 ml of water to 40 gms of powder
2c
single
null
Dental
null
3efc5dca-3d40-4c35-b1f9-0ec1eaf7c9b7
Shawl sign is seen in -
Neonatal lupus
Cutaneous scleroderma
SLE
dermatomyositis
3d
single
Shawl signConfluent macular violaceous erythema on the posterior neck and shoulders in patients of dermatomyositis is called Shawl sign. IADVL textbook of dermatology page 1246
Dental
Autoimmune skin disorders
a38a721f-0ca6-4a5b-95ac-98dfc230ff30
Live vaccines are
TT
BCG
DPT
OPV
1b
single
BCG consists of living bacteria derived from an attenuated bovine strain of tubercle bacilli. The bacilli used for vaccine production are descendants of the original Calmette strain of BCG (refer pgno:196 park 23rd edition)
Social & Preventive Medicine
Epidemiology
47b6d301-78a9-4fec-ad89-44786e43aa10
Prolonged QT interval is not seen in
Hypokalemia
Hypocalcemia
Hypomagnesemia
Hypercalcemia
3d
single
Hypercalcemia: The most common ECG findings of hypercalcemia are a sho QT interval secondary to a shoened ST segment. There may also be a widened or flattened T wave; however, significant hypercalcemia can cause ECG changes that mimic an acute myocardial infarction cuases of prolonged QT Bradycardia Central Nervous Sys...
Medicine
C.V.S
7c49d50e-1e4e-4f98-a56d-312fa0e0a41c
Which of the following is diagnostic of GDM by 75 g GTT as per NICE 2015 criteria?
FBG > 5.1 mmol/L
FBG > 7.0 mmol/L
Fasting blood glucose 5.6 mmol/L
2 hr PP OGTT more than 5.8 mmol/L
2c
single
Ans. is c, i.e. Fasting blood glucose 5.6 mmol/LNICE 2015 guidelines for diagnosing Gestational diabetesGestational DiabetesDiagnose gestational diabetes if the woman has either:-A fasting plasma glucose level of 5.6 mmol/litre or above or-A 2-hour plasma glucose level of 7.8 mmol/litre or above. Also know - Metabolic ...
Gynaecology & Obstetrics
Antenatal Care & Assessment of Fetal Well Being
6a95b06c-9914-4886-8ef3-3adcdfc9ec01
In facial nerve injury, loss of lacrimation is due to involvement of-
Chorda tympani nerve
Buccal nerve
Greater superficial petrosal nerve
Deep petrosal nerve
2c
single
Ans. is 'c' i.e., Greater superficial petrosal nerve o In facial nerve injuryLoss of lacrimation Due to involvment of greater superficial petrosal nerve.Loss of stapedial reflex Due to involvement of nerve to stapedius.Lack of salivation Due to chordatympani.Loss of taste sensation from Anterior 2/3 of tongue: - due to...
ENT
Facial Nerve And Its Disorders
e5b43b26-bb09-471c-aeb2-eab735ded1ef
Polypeptide chain termination is enhanced by
Stop codon
Peptidyl transferase
UAA
All of these
3d
multi
Termination requires stop codon (UAA, UAG, UGA) and releasing factors . Peptidyl transferase is also required which along with releasing factor hydrolyses peptide bond between tRNA at 'P' site and promotes the release of a newly synthesized polypeptide chain from ‘P’ site.
Biochemistry
null
b2fd244b-73e5-4811-9586-4c4dc8b2bfdf
Trauma from occlusion causes all except:
Leads to marginal gingivitis
Reversible in nature
Does not cause pocket formation
Alveolar crest height might be reduced
0a
multi
Clinical features of TFO  Mobility (progressive)  Pain on chewing or percussion  Fremitus  Occlusal prematurities/discrepancies  Wear facets in the presence of other clinical indicators  Tooth migration  Chipped or fractured tooth (teeth)  Thermal sensitivity  Key notes : TFO hardly affects the gingival soft tissues.
Dental
null
96ea09f9-3ee2-4ca2-9a24-e27007cb422a
Which of the following is essential for tumor metastasis
Angiogenesis
Tumorogenesis
Apoptosis
Inhibition of tyrosine kinase activity
0a
single
Ref Harrison 17/e p 509; Robbins 9/e p305_306 Metastasis is a complex series of steps in which cancer cells leave the original tumor site and migrate to other pas of the body ,the bloodstream or the lympatic system ,to do so malignant cells break away from the primary tumor and degrade protein of the extacellular matri...
Anatomy
General anatomy
e97cbd34-ef06-4211-bf7b-c84b1f71b8f3
Poor accessibility is the main disadvantage of _______ flap
Trapezoid
Envelope
Semilunar
Any of the above
2c
multi
null
Surgery
null
7ed5182c-45bd-48e6-bc26-1d59c398fcab
Fatal dose of methanol :
15 ml
30-60 ml
60-250 ml
500 ml
2c
single
C i.e. 60-250 ml
Forensic Medicine
null
e74d9fd8-2fba-4fb0-8f5e-d3119a51d4d4
Shape of the interdental papilla in midline diastema cases is
Pyramidal
Round
Triangular
No specific shape
3d
single
null
Dental
null
c10d7131-8dad-4ac2-b09c-6af1c032e9d2
All of the following immunohistochemical markers are positive in the neoplotic cells of granulocytic sarcoma, EXCEPT:
CD 45 RO
CD 43
Myeloperoxidase
Lysozome
0a
multi
A variety of markers for myeloid precursors in granulocytic sarcoma are identified. CD43, lysozyme, myeloperoxidase and CD 15 are the most sensitive markers staining a large propoion of the cells of the majority of well-differentiated tumors. CD 45 RO is not mentioned as a immunohistochemical marker of granulocytic sar...
Pathology
null
2bf56d57-44f9-4b74-a4b0-725b647c5bb2
Response to iron in iron deficiency anemia is denoted by?
Restoration of enzymes
Reticulocytosis
Increase in iron binding capacity
Increase in hemoglobin
1b
single
Ans. is 'b' i.e., Reticulocytosis Response to iron therapy When specific iron therapy is given, patients often show rapid subjective improvement, with disappearance or marked diminution of fatigue, lassitude, and other non-specific symptoms. This response may occur before any improvment in anemia is observed. The earli...
Pathology
null
117c4aa3-5da8-47c5-b490-9455ba0788a2
Which organism causes toxin shock syndrome ?
Pneumococcus
E. coli
Staphylococcus aureus
Enterococcus
2c
single
Ans. is 'c' i.e., Staphylococcus aureus Toxic shock syndrome TSS is a potentially fatal multisystem disease characterized by sudden high fever, fainting, watery diarrhea, headache and muscle ache. There are two types of TSS :? 1. Staphylococcal TSS Staphylococcal TSS results from the elaboration of toxic shock syndrome...
Microbiology
null
f9c7622e-cfdc-4d84-b35c-e498be027f08
Busacca and Koeppe&;s nodules are characteristically seen in
Residual uveitis
Recurrent uveitis
Granulomatous uveitis
Non-granulomatous uveitis
2c
multi
Non-granulomatous uveitisGranulomatous uveitisBehcet disease HLA - B27 associated ankylosing spondylitis Reiter syndrome Inflammatory bowel disease Idiopathic Infections - Lyme disease, Kawasaki disease, rickettsia, mumps, measles, Chlamydia, influenza, adenovirusPsoriatic ahritis Secondary syphilis Trauma UGH syndrome...
Anatomy
All India exam
9e30d956-4b20-4558-9663-a80209688115
Which of the following centers are involved in maintaining the circadian rhythm?
Supraoptic nuclei
Posterolateral nuclei
Ventrolateral nuclei
Suprachiasmatic nuclei
3d
single
The entrainment process in most cases is dependent on the suprachiasmatic nuclei (SCN) located bilaterally above the optic chiasma. Efferents from the SCN initiate neural and hormonal signals that enteain a wide variety of well known circadian rhythms including the sleep wake cycle and the secretion of the pineal hormo...
Physiology
null
6703721c-b8bf-411a-9763-c8c2a7986a03
P-value is the probability of -
Not rejecting a null hypothesis when true
Rejecting a null hypothesis when true
Not rejecting a null hypothesis when false
Rejecting a null hypothesis when false
1b
multi
• P-value: – Is the ‘Probability of Type I error’ (Null hypothesis is true but rejected) – Significance (a) level: is the maximum tolerable probability of Type I error – P- value is calculated (on basis of data while Alpha is fixed in advance: by the choice of level of significance employed in the test – P – value calc...
Social & Preventive Medicine
null
1e001024-d434-4639-aa41-d506d6a9199b
Which of the following is not a prefabricated pontic:
Long pin facing.
Pontip.
Perel pontic.
Sanitary facing.
2c
single
Example of prefabricated pontics are: Trupontic, Long pin facing, Flatback, Sanitary facings, Reverse pin facing, Pontips.
Dental
null
2422bca1-e571-463d-a199-e6548ae6b8b1
Pneumatocele is caused by?
Staphylococcus aureus
Streptococcus pyogenes
Hemophilus parainfluenzae
Mycoplasma pneumoniae
0a
single
Ans. A. Staphylococcus aureus* S. aureus is a cause of serious respiratory tract infections in newborns and infants; these infections present as shortness of breath, fever, and respiratory failure.* Chest X-ray may reveal pneumatocele (shaggy, thin- walled cavities). Pneumothorax and empyema are recognized complication...
Medicine
Infection
9ea4b27b-90ca-428a-b5ae-df9ae6e8b29b
Psychosurgery is used in ?
Phobia
Generalized anxiety
OCD
Depression
2c
single
Ans. is 'c' i.e., OCD
Psychiatry
null
4eb3ad07-de18-411c-8c57-27739d0379a9
Odynophagia means:
Pain during swallowing
Difficulty in swallowing
Bad odour from mouth
Psychiatric disease
0a
multi
Ans. a (Pain during swallowing). (Ref. Diseases of ENT by PL Dhingra /3rd 402, 444)TermDefinationOdynophagiapainful deglutition.Dysphagiadifficulty in deglutition.Dysphagia lusoriaesophageal compression due to aberrant vessel, leading to dysphagia.Globus hystericusa psychiatric condition characterized by dysphagia.Hali...
ENT
Oesophagus
56fc6e36-0abf-4870-a5ac-093081e1f7b4
In oral poisoning with carbamate insecticides, .............................. may be hazardous:
Pralidoxime
Atropine
Magnesium sulfate purgative
Gastric lavage with activated charcoal
0a
single
Oximes are ineffective in carbamate poisoning. Rather, these can worsen the poisoning due to weak anticholinesterase activity of its own.
Pharmacology
null
f599714b-89fe-4b9c-b997-688ffc087c9b
Which of the following muscle is not supplied by Recurrent Laryngeal nerve: (PGI Dec 2008)
Posterior cricoarytenoid
Thyroarytenoid
Lateral cricoarytenoid
Cricothyroid
3d
single
Ans: D (Cricothyroid) Nerve Supply of LarynxMotorAll the muscle which move the vocal cords (Abductor0- posterior cricoarytenoid; adductorQ-Lateral cricoarytenoid, Interarytenoid & thyroarytenoid: tensorQ-Cricothyroid, vocalis) are supplied by Recurrent Laryngeal nerve1'except the cricothyroid muscle. The latter receive...
ENT
Anatomy of Larynx
83e6466d-f26e-4871-a34e-950e9b4e90fd
All of the following clinicopathologic features are seen more often in seminomas as compared to nonseminomatous germ cell tumors of the testis except
Tumors remain localized to testis for a long time
Thety are radiosensitive
They metastasize predominantly by lymphatics
They are often associated with raised levels of serum AFP and HCG
3d
multi
While hCG concentration may be inceased in patients with either nonseminoma or seminoma histology, the AFP concentration is increased only in patietns with nonseminoma." - Harrison Seminomas represent about 50% of all Germ cell tumors of testis. Median age is 4th decade (Nonseminomas are most frequent in the 3rd decade...
Surgery
Urology
12163f1a-b885-4830-b527-2b8863b0bf3e
Chances of adverse outcome in a hea disease patient are increased in all of the following periods except
28-32 weeks of pregnancy
At the time of labor
4-5 days after delivery
First 4weeks of Pregnancy
3d
multi
Period of pregnancy during which a hea disease patient has high chance of adverse outcome 12 to 16 wks of pregnancy 28 to 32 wks of pregnancy During Labor Immediately after delivery-Maximum deaths 4 to 5 days after delivery Reference: William's Obstetrics; 24th edition; Chapter 49
Gynaecology & Obstetrics
Medical, surgical and gynaecological illness complicating pregnancy
51a13c26-8e46-46cf-9057-70d7f3c98877
Structures preserved in modified radical neck dissection are all except:
Accessory nerve
Sternocleidomastoid muscle
Submandibular gland
Internal jugular vein
2c
multi
null
Surgery
null
764e207c-5756-4e11-ad62-55b2fc1ac023
Which ofthe following drugs is used for Irritable Bowel Syndrome of the constipating type-
Lubiprostone
Cholestyramine
Alosetron
Rifaximin
0a
single
Management of IBS The most impoant steps are to make a positive diagnosis and reassure the patient. Many people are concerned that they have developed cancer. A cycle of anxiety leading to colonic symptoms, which fuher heighten anxiety, can be broken by explaining that symptoms are not due to a serious underlying disea...
Medicine
G.I.T
6e47c395-02bd-4822-95e9-94efb2447db8
Treatment of AIDS include
3 Reverse transcriptase inhibitors
2 Reverse transcriptase inhibitors + 1 Protease inhibitors
2 Reverse transcriptase inhibitors + 2 Protease inhibitors
3 Reverse transcriptase inhibitors + 1 Protease inhibitors
1b
single
(2 Reverse transcriptase inhibitors + 1 Protease inhibitors) (1124-H) (1197-1201-300-CMDT-09) (1190- H17th)Currently licenced drugs for the treatment of HIV infections fall into three categories: those that inhibit the viral reverse transcriptase enzyme: those that inhibit the viral protease enzymes, and those that int...
Medicine
Infection
87fedd7e-aad8-4037-a6ee-d6864f34488c
Eye signs can be seen in :
Primary toxic goitre.
Secondary toxic goitre.
Thyrotoxicosis.
All of the above.
0a
multi
Toxic goitres are broadly of two distinct types: Primary & Secondary.
Surgery
null
59d5aa67-9fd0-46ad-852c-8438c28e847b
Child belongs toBihar Shows hypopigmented patches over his face. What is the right diagnosis?
P. alba
Leprosy
Vitilgo
None
1b
multi
As the child belongs to an endemic area, So our answer is inclined for Leprosy. The disease is clinically characterized by one or more of the three cardinal signs: hypopigmented or erythematous skin patches with definite loss of sensation, thickened peripheral nerves, and acid-fast bacilli detected on skin smears or bi...
Pathology
All India exam
d3657f58-206c-4321-8aae-d735d66a4ade
Fetal middle cerebral artery Doppler is most useful in the evaluation of -
intrauterine growth restriction
Preeclampsia
Fetal anemia
Fetal metabolic disorders
2c
single
Ans-CMCA - PSA for fetal anemia in Rh- pregnancy.
Unknown
null
eed5d1e3-5f54-4dcc-9299-4ad963210f2e
A durck granuloma is seen in -
Brain
Spleen
Liver
Lymphnode
0a
single
Durck granuloma → Ring hemorrhages and small focal inflammatory reaction seen in Brain in cerebral malaria
Pathology
null
d4fdd0ba-a753-4357-8a71-f94ca405c9b5
Most common cause of HUS in children is
E coli 0157/H7
S typhi
Shigella
None
0a
multi
Ans. is 'a' i.e., E coli 0157/H7 The majority of HUS in children (90%) is related to prototypic diarrhea associated form, predominately in previously healthy children 6 months to 4 years of age with a peak between 1 and 2 years. Shiga toxin producing E coli (STEC) is the major cause of diarrhea associated HUS. Specific...
Microbiology
null
2e49c5e0-9f1e-489e-95e6-2744183e62ed
What is first sign noticed in the eye after death of a person?
Corneal haziness
Tache noire sclerotica
Kevorkian sign
None of the above
2c
multi
Fragmentation of blood columns in a retinal vessel is called Kevorkian sign. It is the first sign in eye after death of a person.
Forensic Medicine
null
7988937b-4e25-477b-88c9-eba531c78a71
Carotene is not found in high amounts in -
Tomato
Cabbage
Potato
Spinach
2c
single
The cheapest source is green leafy vegetable such as spinach and amaranth. Vitamin A also occur in most green and yellow fruits and vegetables. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE 21ST EDITION. PAGE NO - 615
Social & Preventive Medicine
Nutrition and health
1ad099d8-81c7-4b1f-b0b9-c2f1793ad8a5
A foy year old female visit the hospital with complaint of pain in her right hypochondriac region radiating towards the right shoulder tip. The pain begins after eating food and increases steadily over the period of 10-30 minutes then gradually decreases. She might have:-
Cholelithiaisis
Peptic ulcer
Acute pancreatitis
None of the above
0a
multi
Most probable diagnosis of this case is cholelithiasis. Cholelithiasis is commonly seen in fat foy feile females. In the given case the patient is experiencing pain after the meals and it increases for the period of 10 mins means during the time of gall bladder contraction to release bile. Gall bladder is supplied by t...
Anatomy
Liver
8e34ea96-e83d-460e-be1b-bbaf299eb4a8
Which of the following is the most common etiological agent in parNasal sinus mycoses:
Aspergillus
Histoplasma
Conidiobolus coronatus
Candida albicans
0a
single
Most common type of fungal infection of nose and paranasal sinuses are due to aspergillus. A.fumigatus>A.niger>A.flavus are the most frequent offenders. Ref Maqbool 11/e,p 255.
ENT
Nose and paranasal sinuses
65b5a04a-c7b9-4e40-b538-3c3a0edc9392
Salmonella osteomyelitis is common in
Sickle cell disease
HIV
IV drug abusers
Pregnancy
0a
single
ANSWER: (A) Sickle cell diseaseREF: Textbook of orthopedics and trauma, By GS Kulkarni, page 289Salmonella osteomyelitis is more common in children with sickle cell disease, hemoglobinopathies and thalassemia. The reason for this higher incidence is as follows:Local thrombosis of intestinal mucosa causes disruption of ...
Orthopaedics
Infection of Bones & Joints
13628d53-22e9-4b43-921b-d28a6e7133bf
Structure passing through foramen Rotundum:
Maxillary aery
Maxillary nerve
Middle meningeal aery
Spinal accessory nerve
1b
single
Maxillary nerve
Anatomy
null
ec4b9ec2-2950-4733-b9c7-9443967c15f8
Sensitivity is
True positive\/ true positive + false negative
True negative\/ false positive + true negative
True negative\/ true negative + false positive
True negative\/ false negative + true positive
0a
multi
Repeated question
Social & Preventive Medicine
Screening
045febbe-3c38-470f-aa66-ca6bee5ab50e
Which of the following is labile cell ?
Cardiac cell
Liver parenchymal cell
Vascular endothelial cells
Surface epithelium
3d
single
Ans. is 'd' i.e., Surface epitheliumWhen a cell proliferates, it pass through a cell cycle. o Cell cycle has a series of phases : -G iphase --> Rest phase (Presynthetic phase) S phase --> Synthetic phase in which synthesis of DNA takes place.a G2phase --> Resting phase (Postsynthetic or postmitotic phase). Mphase --> M...
Pathology
null
41652eec-6997-4258-9119-d06bc5497af9
Spinal accessory nerve leave the cranium via
Foramen magnum
Foramen spinosum
Foramen jugulare
None
2c
multi
null
Anatomy
null
082ccf05-a5d2-4d9b-9ed9-e62fd49d2763
Animal waste such as placenta is disposed by-
Incineration
Autoclave
Microwave
None
0a
multi
- animal wastes comes under category no 2 of biomedical wastes. - it should be disposed by incineration. Reference: Park's textbook of preventive and social medicine, 23rd edition, pg no:793 <\p>
Social & Preventive Medicine
Hospital waste and disaster management, Occupational health
fecd2219-0338-4015-a2ac-e1847a2dafc5
Acute fluoride toxicity is seen at
5 mg
5 grams
5.5 mg
55 grams
1b
single
- 5.0 grams – in AIPG - 2.2 grams – in PGI
Dental
null
0a9f1898-d816-499b-9320-ab8513dd80d7
All of the following are pa of the ASEPSIS wound grading except ?
serous discharge
purulent exudate
Induration
Erythema
2c
multi
REF : BAILEY AND LOVE 27TH ED.
Surgery
All India exam
ac2e1827-f5e1-43d2-9d87-f1a25c32396c
How is under-nutrition defined?
Weight for age < -2 SD
Weight for height < -2 SD
Weight for age < -3 SD
Weight for height < - 3 SD
1b
single
Ans. b. Weight for height < -2 SD (Ref: Ghai 8/e p96)Under nutrition is defined in terms of Height for Height, i. e. < -2 SD. Height for Height < -3 SD is severe under nutrition.Indicators of MalnutritionIndicatorParameterInterpretationStuntingLow height for ageChronic malnutritionQWastingLow weight for heightAcute mal...
Pediatrics
Nutrition, Food Security, and Health
3452d565-b7c5-4c28-a92f-06e12f5d76ea
Which of the following is higher at the apex of the lung than at the base when a person is standing?
V/Q ratio
Blood flow
Ventilation
PaCO2
0a
single
Ans. A. V/Q ratioa. The alveoli at the apex of the lung are larger than those at the base so their compliance is less. Because the compliance is reduced, less inspired gas goes to the apex than to the base.b. Also, because the apex is above the heart, less blood flows through the apex than through the base.c. However, ...
Physiology
Respiratory System
9fe3701c-5fcb-4e53-922b-1340035a240a
Growth factor oncogene is -
myc
fos
sis
jun
2c
single
Sis oncogene is a growth factor. Myc, jun and fos oncogenes are nuclear regulatory proteins Following information have been added in 8th/ e of Robbin's  miRNA and cancer It has already been explained in genetics that miRNA is a gene-silencing RNA, i.e. it inhibits gene expression at post-transcription level. So, miR...
Pathology
null
d700565e-b3a7-4ca8-8317-debd2f6c616a
WHO theme for 2019:
Universal coverage: Everyone, Everywhere.
Depression, lets talk.
Good health adds life to years.
Working together for health.
0a
single
null
Dental
null
1ad5c5d6-7e55-4732-b2d3-bce2e7fc7eeb
A young lady is present with history of repeated episodes of overeating followed by purging using laxatives, she is probably suffering from
Bulimia nervosa
Schizophrenia
Anorexia nervosa
Benign eating disorders
0a
single
Bulimia Nervosa Bulimia nervosa is an eating disorder charac terised by the following clinical features: 1. Bulimia nervosa usually has an onset in early teens or adolescence. 2. There is an intense fear of becoming obese. There may be an earlier history of anorexia nervosa. 3. There is usually body-image disturbance a...
Psychiatry
Sleep disorders and eating disorders
e86b9a60-feb3-4e39-86e9-30e98402c1d8
A neonate delivered at 32 weeks, is put on a ventilator, X–ray shows 'white out lung' and ABG reveals PO2 of 75. Ventilator settings are an, FiO2 of 70, and rate of 50/minute. Next step to be taken should be ?
Increase rate to 60 per minute
Increase FiO2 to 80
Continue ventilation with the same settings
Weaning ventilator
2c
multi
Lets see the individual findings. The neonate is premature. X - Ray shows 'White - Out' : is a sign of Hyaline Membrane disease in the Newborn i.e. RDS. ABG reveals p0, of 75 : which is acceptable. FiO, : Fractional Inspiratory 0„ here in the ventilator settings, is 75% well above the normal. Respiratory Rate settings...
Pediatrics
null
8fa3aab1-eb2c-4d4e-a197-b415a2d6c1c0
True pseudo rosettes are seen in all except
Neuroblastoma
Retinoblastoma
Medulloblastoma
Thecoma
3d
multi
Thecoma *Neuroblastoma: Homer-Wright pseudo rosettes can be found in which the tumor cells are concentrically arranged around the central space filled with neutrophil. *Medulloblastoma: The tumor has the potential to express neural cells or Homer Wright rosettes as occur in neuroblastoma. *Retinoblastoma: In well diffe...
Surgery
null
884150c4-9f48-4c96-b794-dd6ab025aa5a
Burkits Lymphoma is caused by:
HTLV1
HTLV2
HiPV
EBV
3d
single
EBV
Microbiology
null
86c8a07c-feca-47f4-a272-6e1de455c28e
Thymus glands are derived from:
I pharyngeal pouch
II pharyngeal pouch
III pharyngeal pouch
IV pharyngeal pouch
2c
single
null
Anatomy
null
3df95836-75e3-4362-b47a-6bcbb524a92e
Quantitative assessment of liver function can be done by:
Degree of | Transaminases
Degree of |Alkaline phosphatase
Degree of | GGT
Estimation of Galactose Elimination capacity
3d
single
Answer is D (Estimation of Galactose Elimination capacity): Estimation of Galactose Elimination capacity (GEC) is an example of quantitative liver tests Liver Function tests Non quantitative Tests for Liver Function Although generally termed as Liver function tests, these are either not related to function or only refl...
Medicine
null
5a5f3372-b7a1-4785-a039-77b14d830aa5
Which of the following rod is not used with the surveyor?
Incisal guide pin
Analyzing rod
Carbon marker
Wax trimmer
0a
single
null
Dental
null
ec6fca24-29ff-4cf7-95c4-a74936bad74d
Which of the following is true of botulinum toxin?
It is an endotoxin
It acts on the postsynaptic membrane of peripheral nerves to block acetylcholine receptors
It is a neurotoxin, which primary affects the central nervous system
It is a relatively weak neurotoxin
1b
multi
It acts on the postsynaptic membrane of peripheral nerves to block acetylcholine receptors Botulinum toxin is the most potent bacterial toxin known. One microgram of purified toxin is able to kill 200,000 mice. The toxin is released only upon the death and autolysis of the organism, and is thus classified as an exotoxi...
Surgery
null
71978105-71d8-4532-80d0-3d4b5069ce0e
Risk of kernicterus is increased in all except –
Low level of serum albumin
Prematurity
Acidosis
High levels of serum albumin
3d
multi
null
Pediatrics
null
e6a778aa-8efb-435b-be78-82329d4dc5ff
All are disorders of Phagocytosis except
Chronic granulomatous disease
Myeloperoxidase deficiency
Chediak-Higashi Syndrome
Nezelof Syndrome
3d
multi
Nezelof Syndrome is autosomal recessive condition characterised by cellular immunodeficiency.
Microbiology
null