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135
115145c9-fdfc-4995-a9af-94736be9a61d
Which of the following is the side effect of steroids due to its mineralocorticoid component ?
Skin striae
Hypertension
Osteoporosis
Moon face
1b
single
null
Pharmacology
null
9262dbff-96df-4f6f-94c4-569a580682b3
The basal body temperature shift after ovulation is due to
FSH peak
LH peak
Estrodiol
Progesterone
3d
single
Your body temperature dips a bit just before your ovary releases an egg. Then, 24 hours after the egg's release, your temperature rises and stays up for several days. Before ovulation, a woman's BBT averages between36.1degC (97degF) and36.4degC (97.5degF). After ovulation, it rises to36.4degC (97.6degF) to37degC (98.6d...
Physiology
Endocrinology
3b9ad827-1453-44c8-b62b-8421adf5d3da
Which of the following is NOT to be given in cyclic mastalgia is :
Evening primrosa oil
Danazol
Tamoxifen
Estrogen
3d
single
Ans. is d i.e. Estrogen
Gynaecology & Obstetrics
null
79e8c58e-ddc7-4d31-a7ac-e8242caa978b
Ideal investigation for fistula-in-ano is
Endoanal ultrasound
MRI
Fistulography
CT scan
1b
single
CLINICAL ASSESSMENT A full medical history and Proctosigmoidoscopy are necessary to gain information about sphincter strength and to exclude associated conditions. Full examination under anesthesia should be repeated before surgical intervention. Diluted hydrogen peroxide, instilled the external opening, is a very usef...
Surgery
GIT
c4b6c978-5632-488a-a50e-6a6fb74f3047
According to Kaban’s protocol rate of distraction osteogenesis to regenerate a new ramus/ condyle unit is?
1 mm/day
1.5 mm/day
2.0 mm/day
2.5 mm/day
0a
single
null
Surgery
null
a1749fbe-490e-489a-9e73-d00e226f562b
Stainless steel crowns are contraindicated in:
Medically compromised patient
After endodontic therapy
Rampant caries
Amelogenesis imperfecta
0a
multi
null
Dental
null
1c9ed576-9c1c-4bdf-9381-9a145b8b0591
Patient come with a midline swelling in the neck measuring 2cms in size On H P E it shows orphan annie eye nuclei Most likely diagnosis
Papillary thyroid ca
medullary thyroid ca
Toxic nodular goitre
Follicular thyroid Ca
0a
single
Orphan Annie eyed nuclei are characteristic histopathological feature of PTC ref : bailey and love 27th ed
Surgery
All India exam
be852394-a4a3-45c6-b2f3-92f7ab9c2f80
Which is not a feature of Netherton Syndrome?
Autosomal dominant
Ichthyosis
Very short hair
Erythroderma
0a
single
Ans. A. Autosomal dominanta. Netherton Syndrome: This autosomal recessive disorder is characterized by ichthyosis (usually ichthyosis linearis circumflexa but occasionally the lamellar or congenital ichthyosiform erythroderma types), trichorrhexis invaginata and other hair shaft anomalies, and atopic diathesis.b. Mutat...
Skin
Autoimmune Skin Disorders
33109385-ca24-426a-bdaa-70b9f5b1f886
Terminal stage of pneumonia is ?
Congestion
Red hepatization
Gray hepatization
Resolution
3d
single
Ans. is 'd' i.e., Resolution
Pathology
null
6cf32b40-f578-4963-afcc-890ca27761c9
T.T.K.G >8 is seen in all except:
Diabetes mellitus
Acute glomerulonephritis
Adrenocoical insufficiency
Cushing syndrome
3d
multi
Transtubular potassium gradient > 8 is associated with hyperkalemia. Choices 1, 2, 3 lead to hyperkalemia. Choices 1 and 2 lead to kidney damage. Choice 3 due to aldosterone deficiency leads to potassium excess due to inability to loose potassium the collecting duct. Cushing syndrome has excess of coisol, which stimula...
Medicine
Fluids and Electrolyte Imbalance
f51c6484-64df-4513-8752-ae40e274582e
The type of study used in the 10 year Fluoride tablets study can be also be described as a (an)
Case control study
Cross section study
Count study
Experimental study
3d
single
null
Dental
null
c14f51f8-e90e-480a-8149-edf2751cd416
Endophenotypic markers of schizophrenia include all except?
Smooth pursuit eye movement alterations
Saccadic eye movement disinhibition
Prepulse inhibition of stale response paradigm
P50 visual evoked potential
3d
multi
Endophenotypic markers of schizophrenia include: Oculomotor abnormalities Smooth pursuit eye movement alterations Saccadic eye movement disinhibition Prepulse inhibition(PPI) of stale response paradigms Deficits in sensorimotor gating, measured with electroencephalography-based event-related potential (ERP): standardau...
Psychiatry
Basics of Psychiatry
f7f8f371-9571-4129-b26a-4ed06ee58829
Retraction of scapula is by:
Upper fibres of trapezius
Middle fibres of trapezius
Lower fibres of trapezius
Upper & lower fibres of trapezius
1b
single
Ans. B. Middle fibres of trapeziusThe trapezius is a large paired surface muscle that extends longitudinally from the occipital bone to the lower thoracic vertebrae of the spine and laterally to the spine of the scapula.The trapezius has three functional parts: The upper fibers elevate the scapulae, the middle fibers r...
Anatomy
Upper Extremity
966e3d74-9851-4c68-af1e-2c9fd36a7e0a
All of the following are the clinical feature of thromboangitis obliterence, EXCEPT:
Raynaud's phenomenon
Claudication of extremeties
Absence of popliteal pulse
Migratory superficial thrombophlabitis
2c
multi
Clinical features of Thromboangiitis obliterans includes a triad of claudication of the affected extremity, Raynaud's phenomenon, and migratory superficial vein thrombophlebitis. The physical examination shows normal brachial and popliteal pulses, but reduced or absent radial, ulnar, and/or tibial pulses. Claudication ...
Surgery
null
4b1099b0-fc42-436b-8797-5271424680df
This serum immunoglobulin constitutes 80% of immunoglobulins in our body is
IgM
IgA
IgG
IgD
2c
single
80% of immunoglobulins in our body is IgG -major ig Half-life is 23 days Transpoed through placenta Ref: Text book of Microbiology Baveja 5th ed Pg 99
Microbiology
Immunology
e00c42cf-4316-43d9-a18e-acd22ed8940a
Which is the largest pathogenic bacillus ?
Bacillus cereus
Bacillus subtilis
Bacillus megaterium
Bacillius anthracis
3d
single
Ans: D (Bacillius anthracis) Ref: Ananthnarayan R. Paniker CKJ. Textbook of Microbiology. 8th Edition. Hyderabad: Universities Press; 2009. Pg. 242Explanation:Bacillus anthracisConsiderable historical interest is attached to the anthrax bacillus.First pathogenic bacterium to be observed under the microscopeFirst commun...
Microbiology
Bacillus
35eba489-23b5-4315-babb-62fd74b2bed3
Adenoidectomy with Grommet insertion is treatment of choice for:
Serous otitis media in adults
Serous otitis media in children
Adenoiditis in children
Otitis interna in children
1b
single
Ans. (b) Serous otitis media in childrenRef: Dhingra 5th edp. 71-72* Serous otitis media is also known as Glue ear.* It is an insidious condition characterized by accumulation of non-purulent effusion in the middle ear cleft.* One of common causes of serous otitis media (Glue ear) in children is blockage of Eustachian ...
ENT
Disorders of Middle Ear (Otitis Media)
a1b48a6d-ef7c-4fd6-8774-7da069bc190c
Sodium fluoride inhibits which enzyme in Glycolysis
Hexokinase
Pyruvate Kinase
Aconitase
Enolase
3d
single
Inhibitors Enzyme Inhibited Iodoacetate Glyceraldehyde 3 phosphate dehydrogenase Arsenate 1,3 BPG Kinase Sodium fluoride Enolase.
Biochemistry
null
f4726673-fe70-41d6-a541-ffa3185521df
A Toddler has few drops of blood coming out of rectum. Probable diagnosis is
Juvenile Rectal Polyp
Adenoid Polyposis Coli
Rectal Ulcer
Piles
0a
single
Ans is 'a' i.e. Juvenile Rectal Polyp "The aetiology and management of rectal bleeding depends on the age of the child, the type and quantity of bleeding and the associated symptoms. Unlike adults, malignancy is exceptionally rare. In infants, an anal fissure, necrotizing enterocolitis, intussusception and allergic ent...
Surgery
Colon and Rectum - Polyps and Carcinoma
fbc90e2b-7c66-441f-96bd-f37ae9c9744e
Inferior thyroid aery arises from :
1st pa of subclan aery
Thyrocervical trunk of 1st pa of subclan aery
3rd pa of subclan aery
Int. carotid aery
1b
single
B i.e. Thyrocervical Trunk of 1't pa of subclan aery
Anatomy
null
8901a6b2-204d-441e-87cb-2ff0d2a1e7bc
Most common site a spontaneous rupture of esophagus is
Cricopharyngeal junction
Cardioesophageal junction
Mid esophagus
After the crossing of arch of aoa
1b
single
MC site: left posterolateral side of the distal esophagus
Physiology
All India exam
08240a30-122f-435d-b33d-4e0542d52246
A child is born with a single functional copy of a TSG. At the age of 5, the remaining normal allele is lost through mutation. As a result, the ability to control transition from G1 to S phase of cell cycle is lost. Which neoplasm is mot likely to arise in this child?
Retinoblastoma
Breast carcinoma
Adenocarcinoma colon
Cerebral astrocytoma
0a
multi
.
Pathology
General pathology
1393415b-7a9f-4833-9d92-2d4862b9e68a
The end product of one stage fermentation is ?
Formic acid
Pyruvate
Lactate
Ethanol
3d
single
D i.e. EthanolAerobic glycolysis in cells with mitochondria & adequate oxygen supply PyruvateQ is the end product and NADH enters oxidative phosphorylation for ATP productionAnaerobic glycolysis in cells that lack mitochondria (eg RBCs) or deprived of sufficient 0, LactateQ is the end product as NADH formed in glycolys...
Biochemistry
null
1899062c-4a5e-4ee8-beab-4f79d4d80065
Name the incision
Kochers incision
Chevron incision
Lanz incision
Maylard incision
1b
single
This is Chevron incision or roof-top incision or bilateral subcostal incision. Used in PancreaticoduodenectomyKochers is right subcostal incision, for open cholecystectomyLanz incision used in appendicitisMaylard for pelvic surgeries, rectus muscle is cut in this
Surgery
All India exam
417d2dd6-1765-473d-a963-3a5e33320091
All of the following take pa in the pathogenesis of CME in diabetic retinopathy except:
Retinal Pigment Epithelial (RPE) dysfunction
Oxidative stress
VEGF
Increased protein kinase c
0a
multi
A i.e., Retinal pigment epithelial (RPE) dysfunction
Ophthalmology
null
2f4cae57-6862-4ac1-a605-9d7885b7eda9
Which of the following organism can cause acalculous cholecystitis?
Leptospirosis
Malaria
Staphylococcus
Nocardiosis
0a
single
Precipitating factors for acalculous cholecystitis are vasculitis, obstructing adenocarcinoma of the gallbladder, diabetes mellitus, torsion of the gallbladder, "unusual" bacterial infections of the gallbladder (e.g., Leptospira, Streptococcus, Salmonella, or Vibrio cholerae). Reference: Harrisons Principles of Interna...
Medicine
null
ad35c6d0-714a-482c-ab64-0a10799d01bd
Increased density in skull vault is seen in -a) Hyperparathyroidismb) Multiple myelomac) Fluorosisd) Renal osteodystrophy
acd
ad
bc
bde
0a
single
All the causes of generalized increased in bone density can cause increased density of skull vault — Practical imaging 2nd /e 73 Fluorosis and secondary hyperparathyroidism (renal osteodystrophy) cause increased density of skull vault.
Orthopaedics
null
10a4d615-bcbe-4106-b3a4-51ca65c4d4bd
American society of anesthesiologists' physical status classification system, P2 is a is a patient who
Is healthy
With mild systemic disease
With severe systemic disease
None of the above
1b
multi
null
Pharmacology
null
8d0e347a-55a6-47d9-b1a8-bc97b14b7a31
Which one of the following is a rare complication of the use of hormonal contraceptives -
Contraceptive failure
Cardiovascular effects
Carcinogenesis
Metabolic effects
0a
single
Adverse affects of combined Oral contraceptive pills (OCP'S) 1. Cardiovascular effects (Due to oestrogenic component) Myocardial infarction Cerebral thrombosis Venous thrombosis (with or without pulmonary embolism) Hypeension 2. Carcinogenesis Cervical cancer (increased risk). Breast cancer. 3. Metabolic effects (Due t...
Social & Preventive Medicine
Non communicable diseases
eb41c624-9e03-4a44-9aaa-8c0765045628
Number of Golgi tendon organs per 100 extrafusal muscle fibres
20-Oct
200-400
50-60
80-100
0a
single
About 1 golgi tendon organ is responsible for 10 to 20 extrafusal fibers Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:689
Physiology
General physiology
1da9fb1b-78e7-4da5-b282-5ec9b05e2cd9
Remote after Loading is done is?
Stereotactic Radiotherapy
Proton Beam Radiotherapy
External Beam Radiotherapy
Brachytherapy
3d
single
Remote afterloading is done in Brachytherapy in which the system automatically administer a radioisotope directly to cancerous tissue, thereby minimizing the radiation dose to surrounding tissue and eliminating the radiation exposure to hospital staff. In brachytherapy, a radioisotope is placed onto or inside the patie...
Radiology
NEET Jan 2020
6fa2b704-5dc8-4b73-88e8-2eacd895a88a
Which of the following anticoagulant is safest in pregnancy?
Warfarin
Heparin
Phenindione
Dicumarol
1b
single
Oral anticoagulants like warfarin, phenindione and dicumarol can cross placenta and produce teratogenicity if used during pregnancy. Heparin does not cross placenta and is safe in pregnancy.
Pharmacology
Hematology
efafb815-5803-4d09-a0de-6f0e7195b594
Specific stain for myeloblasts is ?
Sudan black
PAS
Myeloperoxidase
LAP
2c
single
Ans. is 'c' i.e., MyeloperoxidaseMyeloperoxidase stainDistinguishes between the immature cells in acute myeloblastic leukemia (cells stain positive) and those in acute lymphoblastic leukemia (cells stain negative).Sudan black B stainThis stain distinguishes between acute lymphoblastic leukemia (cells stain positive) an...
Pathology
null
d64f86a6-9ff7-496d-8161-02a8dfefe2b2
Interventional study is used for:-
Hypothesis Formulation
Hypothesis Testing
Hypothesis Confirmation
Hypothesis Manipulation
2c
single
CLASSIFICATION OF EPIDEMIOLOGICAL STUDIES: 1. OBSERVATIONAL STUDIES: - Descriptive studies - Hypothesis formation is done - Analytical studies - Hypothesis testing is done by coho study/ case-control / cross-sectional/ Ecological studies. 2. EXPERIMENTAL/ INTERVENTIONAL STUDIES: - Hypothesis confirmation is done - Done...
Social & Preventive Medicine
Classification, Coho Study
1d43454b-c546-4c91-8f12-2627708a6543
Tuohy's needle is used for:
Spinal block
Epidural block
Saddle block
Brachial plexus block
1b
single
This is tuohy needle used for epidural anaesthesia
Anaesthesia
Regional Anesthesia
54f20189-6a10-40ca-8ab9-cdbc6bd29979
Treatment for childhood hypothyroidism is with –
T4
T3
Levothyroxine
TSH
2c
single
null
Pediatrics
null
e97747ba-988a-4e0f-8cc4-483734960cf7
A person presented with a tumour at the base of the tongue. What will be the treatment of choice
Wide local excision
Wide local excision + Radiotherapy
Wide local excision + Cervical lymph node dissection
Hemiglossectomy
2c
single
TONGUE CANCER Management of the neck in early stage oral cavity cancer, including the oral tongue, has been discussed above; however, consideration for elective management of the node-negative neck should be made in all instances. When performing surgical excision of the primary tumour, a 1 cm margin in all planes shou...
Surgery
Head and neck
a2f0ac96-fdbe-4dbc-8e26-bc8bc0a84dbe
True about hepatitis A include -a) Virus is destroyed by boiling for 5 minutesb) Spreads by faco-oral routec) Predisposes to cirrhosisd) IgG anti-HIV antibodies used for diagnosis
ab
a
ad
bc
0a
multi
null
Medicine
null
baac8c8f-7b79-4eb5-b27c-77f654a96efe
A Warthin's tumour is:
An adenolymphoma of parotid gland
A pleomorphic adenoma of the parotid
A carcinoma of the parotid.
A carcinoma of submandibular salivary gland
0a
single
Ans. is 'a' i.e. An adenolymphoma of parotid gland Warthin's tumourIt is also called papillary cystadenoma lymphomatosum because, histologically it consists of papillary cystic pattern with marked lymphoid component.Other important characteristics of Warthin's tumour.2nd most common* benign tumour of parotid gland (Ist...
Surgery
Salivary Gland Neoplasms
63b5a86b-9c03-480b-af60-cdfbce9ca141
Causative organism for botryomycosis?
S.aureus
S.pyogenes
Clostridium
Bacillus Cereus
0a
single
S.aureus is the most common agent for botryomycosis. It is a mycetoma-like condition.
Microbiology
null
a90ea77a-eacc-4651-b611-a3644339ae68
Scaphoid fracture is most common in -
Proximal pole
Waist
Distal pole
Tuberosity
1b
single
Ans. is 'b' i.e., Waist * Most common site of scaphoid fracture is the waist of the scaphoid (70%).* Other sites of fracture are proximal pole (20%), distal body (10%), tuberosity, osteochondral fracture.
Orthopaedics
Hand Injuries
d4458f28-f73e-448d-9e33-f8571415ed02
Thiopentone in contraindicated in all except -
Porphyria cuneata tarda
Staticus asthamaticus
Shock
Acute intermittent porphyria
0a
multi
Thiopentone is an barbiturate and being barbiturate it is enzyme inducers thus can precipitate porphyria But depending on enzyme affected it has been found to be safe in Porphyria cuneata tarda and absolutely contraindicated in Acute intermittent Porphyria. fuher being cardiovascular unstable it is contraindicated in s...
Anaesthesia
Intravenous Anesthetic Agents
29e41aba-3d58-4dd3-aa43-1b38276f5564
BP tracking means?
High BP of a child tends to rack along the life
Adults who have high BP today definitely had high BP as child
Daily measurement of BP and recording it to keep a track
BP should be monitored by a BP tracker
2c
single
Park's textbook of preventive and social medicine 23rd edition. IF blood pressure levels of individuals were followed up over a period of years from early childhood into adult life, then those individuals whose pressure were initially high in the distribution would probably will continue in the same tract as adults. Lo...
Social & Preventive Medicine
Non communicable diseases
d22507cb-41c8-4ab3-944d-aac38fc6f771
In which of the following conditions oxygen delivery is least to muscles?
Person inhaling 100 percent oxygen at the top of mout everest
Marathon runner at sea level
Person with carbon monoxide poisoning
None of the above (this option none of the above was also there)
2c
multi
In person suffering from carbon monoxide poisoning , perfusion to the muscle is least Ref: guyton and hall textbook of medical physiology 12 edition page number:353,354,355
Physiology
Respiratory system
7d0f9f68-7b00-4594-ac21-7690b62fd09f
Sphingomyelinase deficiency is characteristic of?
Fabry's disease
Krabbe's disease
Tay Sachs disease
Niemann Pick disease
3d
single
Ans. D. Niemann Pick diseaseSphingomyelinase deficiency is seen in Niemann Pick disease. The enzymes deficient in the other disease are:a. Fabry disease - alpha galactosidaseb. Krabbe's disease - beta galactosidasec. Tay Sachs disease - Hexosaminidase A
Biochemistry
Lipids
8355d18e-447a-4021-8c19-ee70f04c564a
CSF pressure (lumbar) -
70 -180 mm CSF
70 -180 mm CSF
> 200 mm CSF
150 - 200 mm CSF100. The most impoant
0a
single
A i.e. 70-180 mm CSF
Physiology
null
97588f2e-23e8-4724-a65f-169ddfb0f0b9
True regarding haemangioma of the spleen: March 2005
Least common benign tumour of the spleen
May transforms into a haemangiosarcoma
Malignant transformation may be managed conservatively
None of the above
1b
multi
Ans. B: May transforms into a haemangiosarcoma Haemangioma of the spleen is the most common benign tumour of the spleen and may develop into a haemangiosarcoma
Surgery
null
64ebe12f-c35f-415a-b86f-342dfc81d51c
Morphine can be used in all the following conditions except:
Head injury
Asthma
Hypothyroidism
Diabetes
0a
multi
Ref: KDT 6/e p457 Head injury is an absolute contra- indication to morphine use. Hypothyroidism and asthma are relative contra indication.
Pharmacology
Central Nervous system
425d33bf-ca74-4bd8-9e9e-f1c6267549cb
Under the RNTCP, for diagnosis of MDR TB, currently drug sensitivity testing is done for:
Rifampicin
Rifampicin, Isoniazide
Rifampicin, Isoniazide and Ethambutol
Rifampicin, Isoniazide and Pyrazinamide
2c
single
Presently conventional solid egg-based Lowenstein-Jensen (LJ) media will be used for primary culture at the RNTCP accredited laboratory. DST will be performed for streptomycin (S), isoniazid (H), rifampicin (R) and ethambutol (E) only. Pyrazinamide (Z) sensitivity testing may be included at a later period of DOTS-Plus ...
Social & Preventive Medicine
null
7d2ac68d-105a-45e7-a464-4478fb13a674
Cataract is cases of diabetes mellitus is due to accumulation of -
Glycated crytallins
Calcified crystallins
Glycated fibrillins
Calcified fibrillins
0a
multi
In diabetic cataract the mechanisms are belived to be glycation, carbamylation of crystallins and increased oxidative damage. IMG REF
Ophthalmology
Lens
79bf3342-8882-492a-bc66-ae39a939a433
A pragnant woman is diagnosed to suffering form Grave's disease. The most appropriate therapy for her would be-
Radio lodine therapy
Total thyroidectomy
Carbimazole parenteral
Propylthiouracil oral
3d
single
The antithyroid drugs like carbimazole, methimazole crosses the placenta (transplacental passage) and produce fetal hypothyroidism and goiter if the maternal dose is excessive. However, oral propylthiouracil would be the most appropriate therapy in early gestation at low doses as its greater protein binding allows less...
Medicine
Endocrinology
47f3fb15-2f59-430a-bd71-7bed257e6704
Yergason's supination sign is seen in lesion of which muscle?
Triceps
Biceps
Brachioradialis
Supinator
1b
single
Bicipital tendinitis, or tenosynovitis, is produced by friction on the tendon of the long head of the biceps as it passes through the bicipital groove. When the inflammation is acute, patients experience anterior shoulder pain that radiates down the biceps into the forearm. Abduction and external rotation of the arm ar...
Physiology
All India exam
31c5a882-a958-4038-b78c-1f94b6df77b0
Loading of dose of a drug primarily depends on:
Volume of distribution
Clearance
Rate of administration
Half life
0a
single
Ans. A. Volume of distributionLoading dose is dependent on volume of distribution; whereas maintenance dose depends on the clearance.Loading doseMaintenance dose* It is the initial high dose which is given to achieve the desired plasma concentration after saturating (loading) the tissue binding sites.* Just enough drug...
Pharmacology
General Pharmacology
63e85531-f91f-4ed0-b739-5e878321d253
Which of the following is also known as the labourer's nerve?
Ulnar nerve
Median nerve
Anterior interosseous nerve
Radial nerve
1b
single
Median nerve- Labourer’s nerve- involved in coarse movements of hands. Ulnar nerve- Musician nerve- involved in fine movements of hands.
Anatomy
null
259c605a-663c-4c41-8dde-018000ee378a
Which of the ATT drugs is not hepatotoxic?
Pyrazinamide
INH
Rifampicin
Streptomycin
3d
single
Ans. is 'd' i.e., Streptomycin Important educational points* First line antitubercular drugs causing hyperuricemia - Ethambutol, pyrazinamide.* Drugs causing peripheral neuropathy - streptomycin, INH, Ethambutol, ethionamide.* Drugs causing hepatitis - INH, rifampicin, pyrazinamide, ethionamide.* Optic neuritis - INH, ...
Pharmacology
Anti Microbial
c05c73fa-0659-4c86-a2f7-80557cc6ff55
Free fatty acids in blood are carried by?
VLDL
LDL
Albumin
Chylomicron
2c
single
Free fatty acids (FFAs)/ Nonesterified (NEFA) fatty acid : Not esterified with fatty acids. Long-chain free fatty acids Transpoed by albumin. Hydrophobic clefts in the albumin binds to albumin. Sho chain fatty acids (butyrate ) More water-soluble Exist as the unionized acid/ fatty acid anion.
Biochemistry
Lipoproteins
fa88ca49-a519-47af-8515-5b2f8a38b2ce
What is the function of single strand binding proteins (SSBs) during DNA replication
Relieves torsional strain
Deoxynucleotide polymerisation
Prevents premature reannealing of strands
Seals the nick between okazaki fragments
2c
single
Option a: Topoisomerases Option b: DNA polymerases Option d: DNA ligase.
Biochemistry
null
2c159cd3-5ea1-4b01-b59f-15ac68ab4283
In normal X-ray of shoulder which is superior most structure -
Greater tubercle
Surgical neck of humerus
Coracoid process
Head of humerus
2c
single
Ans. is 'c' i.e., Coracoid processo From superior to inferior (important structure on X-ray sholder) Clavicle : Acromian : Coracoid : Superior margin of humeral head : greater tuberc le : anatomical neck : surgical neck.
Radiology
Skeletal System
afd6fdc7-8af7-4451-86cf-01ce18591c5c
What is the recommended dose of steroids for attaining fetal lung maturity?
Inj Betamethasone 12 mg for 2 doses 12 hours apart
Inj Betamethasone 12 mg for 2 doses 24 hours apart
Inj Dexamethasone 6 mg for 4 doses 24 hours apart
Inj Dexamethasone 12 mg for 2 doses 12 hours apart
1b
single
b. Inj Betamethasone 12mg for 2 doses 24 hours apart(Ref: Nelson's 20/e p 852)Inj Betamethasone 12mg IM 2 doses, 24 hrs apart or Inj Dexamethasone 6mg IM every 12 hrs for 4 doses can be used
Pediatrics
Miscellaneous
c24612dd-9fc9-4346-8912-a67a3dc1c9a8
A patient with history of hypertension, with current blood pressure of 170/120 came to your clinic fur or prophylaxis procedures what will be your next step
Wait, monitor and start treatment
Refer to physician
Oral prophylaxis can be done with IV drugs
Oral prophylaxis procedure can be done directly
1b
multi
null
Dental
null
5979ed88-277b-4d94-bc02-29ed39557c60
A male patient suffering from headache, profuse sweating, palpitations and BP.160/110. The drug which will be useful is?
Nifedipine
Labetalol
Prazosin
Phenoxybenzamine
3d
single
Ans- D Phenoxybenzamine Ref - Practice Essentials A pheochromocytoma (see the image below) is a rare, catecholamine-secreting tumor that may precipitate life-threatening hypertension. The tumor is malignant in 10% of cases but may be cured completely by surgical removal. Although pheochromocytoma has classically been a...
Unknown
null
0715c60c-eafc-44e1-8fac-5f4ce8b0b109
Which of the following antibodies is positive in Primary Biliary cholangitis (PBC)
Anti - nuclear antibody
Anti - mitochondrial antibody
Anti - smooth muscle antibodies
CANCA and PANCA
1b
single
Anti mitochondrial antibodies are a signature autoantibody of PBC and are detected in sera of  95% patients.
Pathology
null
569fbe97-f087-4800-b056-ec17b69b4875
Which type of sample can be used to isolate polio virus earliest
Stool
Blood
Throat
CSF
0a
single
null
Social & Preventive Medicine
null
64fda30d-3390-4020-8267-17eb20bffb41
Tretment of pernicious anemia patient with folic acid will improve all except
Nervous lesions
Blood picture
Changes in gut
General symptoms
0a
multi
B 12 resevers will be used up for rbc maturation leaving less of neuronal fuction leading to nerve lesions
Anatomy
General anatomy
a6c6a2f7-8614-4871-a218-982d019dbe69
Standing increases murmur intensity in
Aoic stenosis
Aoic regurgitation
Hyperophic obstructive cardiomyopathy
Mitral stenosis
2c
single
The classic ECG finding in hyperophic obstructive cardiomyopathy is large dagger-like "septal Q waves" in the lateral -- and sometimes inferior -- leads due to the abnormally hyperophied interventricular septum.. Wolff-Parkinson-White, or WPW, syndrome can be associated with HOCM The murmur that is pathognomonic for HC...
Medicine
C.V.S
b0f85896-e1a6-4dbc-924e-c983ce873953
All are diagnostic criteria for irritable bowel syndrome except:
Pain improves with defection
Nocturnal episodes of colicky pain
Onset associated with change in frequency of stool
Onset associated with change in appearance / form of stool
1b
multi
The diagnostic criteria for irritable bowel syndrome is - Recurrent abdominal pain or discomfo for at least 3 days per month associated with > 2 or more of the following features - Pain improvement with defecation Onset with change in form / appearance of stool Onset with change in frequency of stool Nocturnal diarrhea...
Medicine
Malabsorbtion Syndrome
a35c9baf-e914-4c7e-8096-d0ed4fa3e4c6
True about Splenunculi:
It is encapsulated
MC site is tail of pancreas
Often single
Have more red pulp than spleen
0a
multi
Ans. (a) It is encapsulatedRef: Bailey and love, 27th ed; pg. 1178* Splenunculi or Accessory spleen is the most common of all splenic anomalies accounting for 10-30% of population* Formed due to incomplete fusion of embryologic splenic tissue during 5th week leading to the formation of accessory spleen, which is more c...
Surgery
Spleen
7ea294ce-f1ec-474e-a723-50310440a05f
who gave the concept of saftey needs in the heirachy of motivation
lorenz
seligman
freud
maslow
3d
single
ABRAHAM MASLOW Gave the hierarchy of needs It is also called as hierarchy of motivation According to Maslow the basic needs should be met to move on to the next stage Once the basic step is attained, we work on to the higher stage The final stage is self-actualization, that is acceptance of your positives, negatives, s...
Anatomy
Treatment in psychiatry
a24a60c3-549c-479d-926a-d4149156cacd
"Snowflakes" cataract is seen
Diabetes
Galectosemia
Trauma
Wilson's disease
0a
single
A. (Diabetes) (181 - Khurana 4th)True Diabetic Cataract - It is also called "snow- flake cataract" or "snow storm cataract". It is rare condition usually occurring in young adults due to osmotic overhydration of the lens. Initially a large number of fluid vaccoules appears underneath the anterior and posterior capsules...
Ophthalmology
Lens
e826a9e2-3b76-4ab8-a6d1-54c2999ae9fc
A 60-year-old female presented to the OPD with complaints of left jaw pain along with fever. On examination, Poor dentition Area of purulent drainage in the mouth Right sided facial swelling Diffuse mandibular tenderness Medication history includes alendronate and lisinopril. Microscopic examination of the purulent sec...
Penicillin
Azithromycin
Griseofulvin
Metronidazole
0a
multi
This is a case of osteonecrosis of jaw which is a risk factor for Actinomyces infection. 1st image shows lesions from bisphosphonate-related osteonecrosis of the jaw at extraction sites of upper central incisors. Microscopy shows chronic inflammatory changes with Sulphur granules. Actinomyces It has propensity to infec...
Unknown
Integrated QBank
ca80ddf8-0057-4107-b39a-bfe7f83259a8
The plasticizers used in polyether impression material is:
Polyether polymer
Colloidal silica
Glycol ether
Di-vinyl poly (dimethyl siloxane)
2c
single
null
Dental
null
cd52b4f4-e798-4afe-8cb1-04a3639950d6
In a worker engaged in stone breaking with a chisel and hammer, the most common foreign body which can be lodged in his eye is:
Stone paicle
Paicle from the chisel
Piece from the hammer
All of the above
1b
multi
Ans. Paicle from the chisel
Ophthalmology
null
6b3336f4-93f4-47e9-93f0-209b072c592b
Drug of choice for primary open angle glaucoma:
Beta blockers
Prostaglandin analogues
Alpha agonists
Cholinergics
1b
single
Prostaglandin analogues are now the drug of choice for open angle glaucoma and normal tension glaucoma.
Ophthalmology
Glaucoma
98759ea8-cfd9-41e8-8ad2-fc6ed0437880
Vegetations on undersurface of A.V. valves are found in:
Acute Rheumatic corditis
Limban Sack's endocarditis
Non thrombotic bacterial endocarditis
Chronic rheumatic carditis
1b
single
Answer is B (Libman Sacks Endocarditis) Vegetation on under-surface of AV valves are typically seen in Libman Sacks Endocarditis (SLE).
Medicine
null
36d9dd18-5e78-4c02-a8e8-c868fd7859a0
Colopotomy is done to treat -
Ischeorectal abscess
Pelvic abscess
Appendicular abscess
Perianal abscess
1b
single
Ans. is 'b' i.e., Pelvic abscess
Surgery
null
87765e06-a8fc-4deb-beb0-e8a894b20acb
Bilateral lymphadenopathy , along with non caseating granulomas is a characteristic feature of
Sarcoidosis
Scleroderma
SLE
Stein-leventhal syndrome
0a
single
Patients are usually evaluated for possible sarcoidosis based on two scenarios .In the first scenario, a patient may undergo biopsy revealing a noncaseating granuloma in either a pulmonary or an extrapulmonary organ. In the second scenario, signs or symptoms suggesting sarcoidosis such as the presence of bilateral aden...
Anatomy
Respiratory system
887ff857-d31e-43e9-bf3f-d0ab0ef5542a
Treatment of Papillary Ca of Thyroid with bony metastasis
Radiotherapy
Radioiodine
Near total thyroidectomy with radiotherapy
Near total thyroidectomy with radioiodine & radiotherapy
3d
single
Ans. is 'd' i.e. Near total thyroidectomy with radioiodine & radiotherapy As already mentioned in previous question, Total or Near total thyroidectomy is t/t of choice in PTC and also FTC (except minimally invasive cancer). Radioactive iodine '3'1is used post-operatively to detect and destroy any metastatic disease. It...
Surgery
null
95d3875a-c543-4316-a11e-41ed6ce3eb4e
In recent memory loss, probable lesion is in
Thalamus
Temporal lobe
Frontal lobe
All of the above
1b
multi
The Neuropsychology of Autobiographical Memory The medial temporal lobe memory system includes the hippocampus formation and the adjacent parahippocampal and perirhinal coices. The hippocampus is not the place where the content of memories is stored, but rather appears to contain a set of neural links to the content, w...
Medicine
C.N.S
e18be598-6d3d-4e54-a101-76ba589cc87c
Cranial nerve related to apex of the petrous temporal bone
VIII
VII
VI
V
2c
single
In the intraneural course,the fibres of VI nerve runs veically and downwardsthrough the trapezoid body,medial lemniscus and basilar pa of the pons to reach the lower border of the pons. The nerve is attached to the lower border of the pons,opposite the upper end of the pyramid of the medulla. The nerve then runs upward...
Anatomy
Head and neck
2aba8f3a-d451-4fb0-91eb-9e740836110a
Hepatotoxic inhalational agent
Halothane
Enflurane
Desflurane
Sevoflurane
0a
single
All inhalational agent cause maild hepatotoxicity by decreasing hepatic blood flowIsoflurane is the agent of choice in liver disease as it has least effect on Hepatic blood flowDirect hepatotoxicity (Hepatitis, hepatic necrosis) is caused by- halothane, chloroform, trilene, methoxyflurane(Refer: Morgan and Mikhail's Cl...
Anaesthesia
All India exam
d02994f7-52b3-4680-bad6-0cf0042494dd
Which of the following drug can be given intravenously,epidurallyor by transdermal route
Thiopentone
Succinylcholine
Vecuronium
Fentanyl
3d
multi
null
Anaesthesia
null
a685c384-ca50-463f-8020-5683afb209fb
True about subcutaneous nodule in Rheumatic fever ________
Non tender
Most common manifestation
Present on extensor surfaces
Associated with athritis
0a
multi
Subcutaneous nodule in RHD is seen in 3 to 20% cases,non tender,on bony prominence like elbow,shine,occiput ,mostly associated with carditis. Ref : Ghai essential of pediatrics, eighth edition ,p.no:436
Pediatrics
C.V.S
87cbea98-e8fc-455b-b20c-28313725e5ca
Which vaccine gives herd immunity-
OPV
Typhoid
Cholera
None
0a
multi
Ans. is 'a' i.e., OPV o The vaccine progeny of OPV is excreted in the faeces and secondary spread occurs to household contacts and susceptible contacts in the community. o Non-immunized persons may therefore, be immunized. o Thus widspread "herd immunity"results, even if only approximately 66% of the community is immun...
Social & Preventive Medicine
null
31cd39e5-3fdd-408b-9c1e-39ed4a2cb5e3
A 50-year-old lady sprained her ankle 2 months back from which she made a steady recovery. 2 months after the injury she gradually developed severe pain in her right ankle with the significant limitation of ankle movement. Clinical examination reveals oedema and shiny skin. What is the likely diagnosis?
Fibromyalgia
Complex Regional pain syndrome Type I {CRPS I}
Complex Regional pain syndrome Type II {CRPS II}
Peripheral Neuropathy
1b
multi
COMPLEX REGIONAL PAIN SYNDROME (ALGODYSTROPHY) Sudeck, in 1900, described a condition characterized by painful osteoporosis of the hand. The same condition sometimes occurs after fractures of the extremities and for many years it was called Sudeck’s atrophy. It is now recognized that this advanced atrophic disorder is...
Orthopaedics
null
b99a121a-9056-465d-b002-3dd672b4c194
True about subendocardial hemorrhage is all except
May be seen after head injury
Involves RV wall
Continous pattern of sheet like
Flame shaped hemorrhages
1b
multi
Subendocardial hemorrhages (SEH) occur after cardiac injuries and resuscitation as well as secondary to noncardiac injuries comprising head injuries, infectious diseases, intoxications, hemorrhagic diathesis, abdominal trauma, asthma, and hypovolemic shock. In paicular, the common incidence of SEH in intracranial lesio...
Pathology
Cardiovascular system
4dc2ecc6-140a-4b61-a0e4-0748f7349462
Antihormone used in Infeility is:
Mifepristone
Clomifene
Danazol
Finasteride
1b
single
Clomifene citrate : Anti-estrogenic -effects on the Hypothalamic axis which promotes release of FSH and LH which induces folliculogenesis and ovulation. Finasteride: Competitive inhibitor of enzyme 5 alpha reductase. with anti androgenic propeies Mifepristone: antiprogesterone used for inducing aboions Danazol: antiest...
Gynaecology & Obstetrics
Infeility (Eggs'plantation!)
4f5e9a9e-e0f2-451c-b8e2-5c1967480f9e
Anaesthesia contraindicated in volvulus of gut is –
Halothane
Nitrous oxide
Ketamine
Pancuronium
1b
single
null
Anaesthesia
null
cf13a76b-e712-4bb6-872c-07fee87b7352
Which of the following is related to floor of middle ear?
Round window
Internal carotid aery
Internal jugular vein
Tegmen tympani
2c
single
The floor or Jugular Wall of the middle ear is formed by a thin plate of bone which separates the middle ear from the superior bulb of the internal jugular vein. This plate is a pa of the temporal bone, Near the medial wall, the floor presents the tympanic canaliculus which transmits the tympanic branch of the glossoph...
Anatomy
Head and neck
579121f5-475a-4d4d-a1aa-13812e113dba
Therapy of choice for sleep-apnea syndrome is
Invasive ventilation
Non - Invasive ventilation
Oxygen inhalation
Use of respiratory stimulants
1b
single
Harrison's principles of internal medicine 17th edition. * Majority of patients need to use continuous positive airway pressure(CPAP) delivered by a nasal mask every night to splint the upper airway open.
Medicine
C.N.S
9653bec3-0400-4a4f-8bac-e669d799c9fb
Serious infections can occur when absolute neutrophil count decreases below
<500/microliter
<800/microliter
<1000/microlitre
<2000/microliter
0a
single
.
Anatomy
All India exam
18216745-0f76-4b74-afe0-37d803df7e9e
Siffert katz sign seen in
Chondromalacia patella
Blount's disease
CTEV
Rocker Bottom foot
1b
single
null
Orthopaedics
null
71224648-b669-4682-953b-f616d6853331
Osteochondritis in Kohler&;s disease affects which bone ?
Lunate
Patella
Navicular
Femur head
2c
single
types of osteochondritis Bones affected Kohler Navicular Keinbock Lunate Pehes Femur head Johanson- Larsens lower pole of patella REF : MAHESWARI 9TH ED
Anatomy
Avascular necrosis and osteochondroses
23a22d1d-13c1-41a0-a52c-e1edd26d7004
Esthesioneuroblastoma arises from:
Olfactory epithelium
Ethmoid sinus
Maxillary sinus
Sphenoid sinus
0a
single
Ans. (a) Olfactory epitheliumRef: Dhingra's ENT 6th edJ 204* Esthesioneuroblastoma usually arise from the olfactory epthelium . It's a rare tumor of any age group .* Presentation of tumor: cherry red, polypoidal spots mass in upper third of nasal cavity. It is a vascular tumor that bleeds profusely on biopsy.
ENT
Tumors of Nose and PNS
950d44a9-0d6c-4434-9782-afcaa1aa8bb9
A patient 45 years of age, non diabetic, presents with chronic pelvic pain of 1 year duration. She also complains of frequency, urgency and a sense of incomplete evacuation since 1 year without any significant finding on her past ultrasounds, urine examination and urine and high vaginal swab cultures. On pelvic examina...
Urethral syndrome
Asymptomatic bacteriuria
Vulvovaginitis
Cystitis
0a
single
Urethral syndrome Urethral syndrome is defined as a symptom complex including dysuria, frequency, urgency, suprapubic discomfo , post void fullness and dyspareunia in the absence of any abnormality of urethra or bladder. Cause is unceain and is attributed to subclinical infection, urethral obstruction, psychogenic and ...
Gynaecology & Obstetrics
Genitourinary Fistula
3c522f24-c40e-48d2-bcda-87fe2875a115
Shoest acting anticholinesterase is ?
Edrophonium
Pyridostigmine
Glycopyrrolate
Neostigmine
0a
single
Ans. is 'a' i.e., Edrophonium Edrophonium is the shoest acting anti-ChE. When carbamates (other than edrophonium) and organophophates react with cholinesterase, they form covalent bond at esteratic site, which is considerably resistant to hydrolysis. In contrast, edrophonium binds electrostatically and by hydrogen bond...
Pharmacology
null
f0e9729f-ca44-46b1-b38a-ad852f9121ff
True about myasthenia gravis
Associated with thymomoa in 3/4 of cases
Incremental response seen with repetitive electric stimuli
Skeletal muscle function improve after rest
Edrophonium test negative
2c
multi
*The weakness increase during repeated use and may improve following sleep or rest.only 10% of cases are associated with thymomas 65% with hyperplasia of thymus. Edrophonium test is positive. In electrodiagnostic testing MG patients show a rapid reduction of >10-15% in the amplitude of evoked response. Ref Harrison20th...
Medicine
C.N.S
4463291d-273a-4e5a-aaff-f33e0dd96bbc
Which of the following is true about Facial recess?
Medial to veical pa of facial nerve
Lateral to horizontal pa of facial nerve
Medial to horizontal pa of facial nerve
Lateral to veical pa of facial nerve
3d
multi
O Facial recess or posterior sinus is a depression in posterior wall lateral to pyramid. O It is bounded medially by the veical pa of Facial nerve, inferiorly by the chorda- facial angle and superiorly by fossa incudis. O Surgically, facial recess is impoant, as direct access can be made through this into the middle ea...
ENT
Anatomy of Middle Ear
859a92cd-2229-4a00-830d-1cded7f001ca
Treatment recommended for secondary syphilis is
Benzathine penicillin G 2.4 mIU i.m weekly, 3 doses
Benzathine penicillin G 2.4 mIU i.m single dose
Benzathine penicillin G 2.4 mIU i.m twice weekly, 4 doses
Benzathine penicillin G 2.4 mIU i.m twice daily for 2 weeks.
1b
single
null
Gynaecology & Obstetrics
null
cfc9f5f2-8252-4224-96b8-81ec993a58b6
The risk of neonatal chicken pox is the maximum, if maternal infection occurs :
During the first trimester
During the second trimester
Within five days of delivery
Within six weeks of delivery
2c
single
Risk of neonatal chicken pox is maximum if maternal infection occurs near delivery (5 days before delivery or 48 hours after).
Pediatrics
null
99806225-7a27-4bd9-b629-cae760eb25a4
Which of the following condition is using laparoscopy as the diagnostic tool of investigation?
Endometriosis
Ca uterus
Ca cervix
Ca rectum
0a
single
Laparoscopy is the primary method used for diagnosing endometriosis. Laparoscopic findings are variable and may include discrete endometriotic lesions, endometrioma, and adhesion formation. The pelvic organs and pelvic peritoneum are typical locations for endometriosis. Lesions are variable colors, which may include re...
Gynaecology & Obstetrics
null