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b187cde0-0d31-42ea-a84d-6b4109c0aa8f | Ergot alkaloids are used in all except - | Migraine | Acromegaly | Hypertension | Parkinsonism | 2c | multi | Ans. is 'c' i.e., Hypertension Uses of ergot alkaloids1. Migraineo In migraine, throbbing headache is due to dilatation of pain sensitive arteries outside the brain, i.e. extracerebral vessels.o Ergot alkaloids are vasoconstrictor (due to a agonistic action) and oppose these effects,o Ergot alkaloids used in migraine -... | Pharmacology | C.N.S |
36b1e3a9-5596-4992-8729-3b39ac3fd97b | HLA B27 is positive in | Ankylosing spondylitis | Rheumatoid ahritis | SLE | Behcet syndrome | 0a | single | Ref Robbins 8/e p193; Harrison 17/e p2051 ;9/e p215 The HLA complex, which is located on the sho arm of human chromosome 6, contains sequences encoding about 100 genes, most involved in the regulation of the immune response. HLA genes are classically grouped into three major classes. | Anatomy | General anatomy |
80688b75-8dca-4679-a39d-9545c44e9b34 | In RMNCH+A Startegy, what is plus - | Adolescent health | Reproductive health | DPT Vaccination | Newborn health | 0a | single | Ans. is 'a' i.e., Adolescent health o The RMNCH+A strategy is based on provision of comprehensive care through the five pillars, or thematic areas, of reproductive, maternal, neonatal, child, and adolescent health, and is guided by central tenets of equity, universal care, entitlement, and accountability. The "plus" wi... | Social & Preventive Medicine | Health Programmes in India |
f75b679a-359b-4ea9-a6b3-aefae2cbe6ea | What is deposited in Kyser-FIeischer ring - | Copper | Lead | Mercury | Heme | 0a | single | Ans. is 'a' i.e., CopperKayser-FLeischer (KF) ring - Copper deposition in Chalcosis or Wilson's diseaseFleischer ring - Deposition of iron and is a sign of keratoconus | Ophthalmology | Cornea |
ee2e513a-9600-4ccf-a21b-5fc53c244ceb | Psammoma body found in - | Papillary Ca thyroid | Follicular Ca thyroid | Medullary Ca thyroid | Anaplastic Ca thyroid | 0a | single | Ans is 'a' i.e. Papillary Ca Psammoma bodies found in: Ref. Papillary Ca of thyroid 8/e p1122 (7/e p1178) Serous cystadenoma of ovary 8/e 1044 (7/e p1096) Meningioma 8/e p1338 (7/e p1409) Papillary type of Renal cell carcinoma 8/e p966 (7/e p1018) Pitutary adenoma (Prolactinoma) 8/e p1103 (7e p1160) Appendiceal carcino... | Surgery | null |
67f9b675-df37-4997-85cb-e5c0b65d205d | In this poisoning, the vomitus is: | Bluish green | Black | Brown | Red velvetty | 0a | single | GIT symptoms with boric acid can mimics acute gastroentritis. Nausea, vomiting (bluish green), haematemesis, diarrhoea (bluish green) | Forensic Medicine | Toxicology - 1 |
22d07568-d0cc-4d7d-976a-03421c1eb49d | High or low fistula is ano is termed according to its internal opening present with reference to | Anal canal | Dentate line | Anorectal ring | Sacral promontary | 2c | single | The anorectal ring marks the junction between the rectum and the anal canal. It is formed by the joining of the puborectalis muscle. the deep external sphincter, conjoined longitudinal muscle and the highest pa of the internal sphincter. The anorectal ring can be clearly felt digitally, especially on its posterior and ... | Surgery | G.I.T |
d389e0b7-7190-496d-8d35-e51fad76aab8 | Wobble hypothesis -regarding the variation true is: | 3 - end of anticodon | 5 - end of anticodon | m-RNA | t-RNA | 1b | multi | B i.e., 5-end of anticodon | Biochemistry | null |
72cda82b-2bdc-4846-accb-b13ded41d111 | isolated conjugated hyperbilirubinemia is seen in the following conditions except- | Hemolysis | Gilbe syndrome | Crigler-Najjar syndrome | Dubin-Johnson syndrome | 1b | multi | Gilbe's syndrome is by far the most common inherited disorder of bilirubin metabolism . It is an autosomal recessive trait when caused by a mutation in the promoter region of the gene for UDP-glucuronyl transferase enzyme (UGT1A1), which leads to reduced enzyme expression. It can be inherited in a dominant fashion when... | Medicine | G.I.T |
382994cb-2ec5-4441-8859-0472bc8c538d | True about inverted papilloma is - | It is also known as Schnedrian papilloma | Anatomically It has an inverted appearance | It may cause basal cell carcinoma | It is commonly seen in young girls | 0a | multi | Ans. is 'a' i.e., It is also known as Schnedrian papilloma "Inverted papilloma of nose" -o It is also called Schneiderian papilloma, squamous papilloma or papillomatosiso It is a polypoid mass occuring on the lateral nasal wall typically in middle aged men.o The name is derived from its histologic appearance of on inve... | Surgery | E.N.T. |
01835b22-2e3d-4e80-a64d-26f5c29bc227 | Treatment of rectal prolapse in childhood is - | Lahaut's operation | Incision of prolapsed mucosa | Thiersch wiring | Ripstein operation | 2c | single | • Prolapse during childhood is best managed conservatively, the only exception is persistence of prolapse despite effective treatment of diarrhea, worm infestation and malabsorption. These cases are managed by surgery. | Surgery | null |
d010c2e6-6b29-44fb-aa91-29f2d53409c9 | All are true about subacute combined degeneration of spinal cord except - | Due to deficiency of vitamin B12 | Posterior column involvement | Corrticospinal involvement | Absent deep tendon reflexes | 3d | multi | null | Medicine | null |
99de6a97-2596-494d-9422-2a19d28b7ab3 | The most common and the most poorly tolerated heart disease during pregnancy is: | Mitral stenosis | Mitral regurgitation | Aortic stenosis | Aortic regurgitation | 2c | single | Ans. c (Aortic stenosis). (Ref. Dutta, Obstetrics, 6th ed., p 281)# Aortic stenosis has maternal mortality of 15-20% and Perinatal loss of 30%.HEART DISEASE IN PREGNANCY# The risk of fetal congenital malformations is increased by 3-10% if either parents have congenital lesions.# In mother with ASD, risk of having conco... | Gynaecology & Obstetrics | Miscellaneous (Gynae) |
1446f7e3-12e3-4bcd-bd82-c85a714ba064 | Which of the following is true of small bowel carcinoids | Most common site is duodenum | It does not cause endocardial fibroelastosis | Increased risk of Ca lung | None | 3d | multi | Ans. is 'none' Lets see each option one by one Most common site: Most common site for small bowel carcinoids is ileum. About 70-87% are present within the ileum and 40-70% are within 2 ft of the ileocecal valve. Among all carcinoids most common site is GI tract 2nd most common site is respiratory tract Endocardial fibr... | Surgery | null |
0e875125-369d-4715-a798-2b80280533a6 | The obstruction of two or more major hepatic veins is seen in | Budd-Chiari syndrome | Reye's syndrome | Rotor syndrome | Crigler-Najjar syndrome | 0a | single | Budd-Chiari syndrome It is caused by obstruction of hepatic venous outflow producing intense congestion of the liver Etiology Polycythemia rubra Vera is the most common etiology In the West, thrombosis of the major hepatic veins is more common In BCS all three major hepatic veins usually are occluded Small hepatic vein... | Anatomy | G.I.T |
f2beed25-278e-493b-8d39-a93fd47ad74d | Sympathectomy is indicated in | Buerger’s disease | Atherosclerosis producing ischemia of limbs | Raynaud’s disease | All of the above | 3d | multi | null | Surgery | null |
53f5b9b3-66f7-4288-a987-aba31d43dd20 | A man presents with chest pain. ECG shows ST-segment depression in leads V1-V4. Which of the following should not be given? | Beta blocker | Thrombolytic | Morphine | Aspirin | 1b | single | Thrombolytics like streptokinase, alteplase, reteplase are beneficial to patients with ST-elevated MI Max. benefit will be seen if they were given with 6 hours of the onset of MI Their use in ST depressed MI is contraindicated | Pharmacology | Cardiovascular system |
4c725d08-f995-4d7a-9b29-6d2da844d7c3 | The antihypeensive agent that should be avoided in young females and is used topically to treat alopecia is: | Hydralazine | Prazosin | Minoxidil | Indapamide | 2c | multi | Minoxidil is a powerful vasodilator Active metabolite of minoxidil is an opener of ATP sensitive K channels; causes vasodilatation by hyperpolarizing smooth muscle. Minoxidil is avoided in young females because it causes Hirsutism. Drugs causing Hirsutism: Phenytoin Cyclosporine Minoxidil USE OF MINOXIDIL IN ALOPECIA -... | Pharmacology | Hypeension, Arrhythmias, Dyslipidemia |
e89c60e7-82cf-4a17-bfd9-be302f7831a7 | Shoest acting non depolarizing muscle relaxant is | Mivacurium | Doxacuronium | Pipecurium | Vecuronium | 0a | single | Suxamethonium (succinylcholine) is the shoest acting skeletal muscle relaxantMivacurium is the shoest acting nondepolarizing skeletal muscle relaxant.(Refer: stoelting's pharmacology and physiology in anaesthetic practice, 5th edition, pg no.139) | Anaesthesia | All India exam |
474c551b-2a04-490f-8e91-7d99918e4142 | Active immunity is not acquired by:(1994) | Infection | Vaccination | Immunoglobulin transfer | Sub clinical infection | 2c | single | Ans: c (Immunoglobulin transfer)Ref: Ananthanarayan Micro, 7lhed, p. 76 & 6th ed, p. 73 | Microbiology | Immunology |
8df91b2e-08e1-41bf-aa65-38acb2c42ba0 | An HIV patient complains of visual disturbances. Fundal examination shows bilateral retinal exudates and perivascular haemorrhages. Which of the following viruses are most likely to be responsible for this retinitis- | Herpes simplex | Varicella zoster | Cytomegalovirus | EBV | 2c | single | This is a typical feature of Cytomegalovirus (CMV) retinitis. Pizza pie appearance of fundus in CMV retinitis.(In HIV +ve patient, if CD4+ count is <50 cells/ microlitre) Herpes simplex- type 1 : conjuctivitis and corneal ulceration. Varicella zoster-corneal ulcer and zoster opthalmicus. EBV- not associated with retini... | Microbiology | Virology (General Propeies, DNA Viruses) |
6f9763f0-3301-4ba8-9a92-bd32b7fc1834 | Most common cause of gangrene of foot of 30-years old farmer who is a chronic smoker | Raynaud’s disease | Myocardial infarction | Atherosclerosis | Thromboangitis obliterans | 3d | single | null | Surgery | null |
d27dbf35-76e9-40bc-8fdf-9222c625f1d0 | Fogo selvagem is a type of: | Pemphigus vulgaris | Pemghigus vegetans | Pemphigus foliaceus | Bullous pemphigoid | 2c | single | Endemic pemphigus foliaceus common in rural pas of South America, paicularly ceain states of Brazil is known as fogo selvagem (wild fire) caused by bite of black fly. Ref: Rook's textbook of dermatology, 8th edition, Pg 40.13 | Skin | null |
f7986f8a-eac8-4cc2-b90f-2de79c6bcd03 | All are aromatic amino acids EXCEPT: | Phenylalanine | Tyrosine | Tryphophan | Lysine | 3d | multi | (Lysine): Ref 49, U.S. (75- R.S. 7th)* Aromatic amino acids: Phenylalanine, tyrosine and tryptophan (with indole ring) are aromatic amino acids, Basides these histidine may also be considered this category.* Hydroxyl group containing amino acids: - Serine, Threonine, Tyrosine* Amino acids with aliphatic side chains: - ... | Biochemistry | Proteins and Amino Acids |
5b4026f8-b4f7-40b9-84a9-86467664bdb1 | The peak of fast EPSP or, fast IPSP is seen at what time after stimulus application: | 0.5 ms | 0.5 to 1.5 ms | 11.5 ms | 100-500 ms | 1b | single | Fast EPSP and fast IPSP begins 0.5 ms after the stimulus (known as latency). They peak 1-1.5 ms after the stimulus then decreases exponentially. Fast EPSP is due to influx of Na+ and or Ca++ in post synaptic neuron. Fast IPSP is due to influx of Cl- in post synaptic neuron. | Physiology | Introduction to Central Nervous System |
bb474165-d1bf-4450-8a52-5c97bbfc4f9d | Popcorn cells are seen in: | Hodgkin’s lymphoma | Non-Hodgkin's lymphoma | Burkitt’s lymphoma | Multiple myeloma | 0a | single | Hodgkin lymphoma is currently classified in the following manner:
Nodular lymphocyte-predominant Hodgkin lymphoma.
Classical Hodgkin lymphoma (comprising five histopathologic subtypes):
Lymphocyte rich
Nodular sclerosis
Mixed cellularity
Lymphocyte depletion
Unclassifiable
These names describe the most prominent hi... | Pathology | null |
15dc92b8-8da6-41eb-862d-21d0ed2db8ae | Micro RNA is - | Splicing RNA | Snurps | Gene Silencing RNA | Ribonuclease | 2c | single | Ans. is 'c' i.e., Gene Silencing RNA o There is a class of genes that encode for gene-silencing RNAs, i.e. RNAs that do not encode proteins but instead inhibit gene expression (unlike mRNAs) which encode for proteinso Two important gene-silencing RNAs are :- (i) Micro RNAs, and (ii) small interfering RNAs (siRNAs). i) ... | Biochemistry | Molecular Genetics |
71a970cf-92e3-4353-9f43-497456e6ca80 | Concurrent list does not encompass: | Prevention of extension of communicable disease from one unit to another | Prevention of adulteration of food stuffs | Regulation and development of medical profession | Vital statistics | 2c | single | The regulation and development of medical profession is not included in the concurrent list and instead is placed in the Union list and is controlled by the union health ministry. Ref: Park Textbook of Preventive and Social Medicine, 19th Edition, Page 730 | Social & Preventive Medicine | null |
4aeeec74-d9ec-47e0-829d-f0b8bf2cd56a | Which of the following in halational agent sensitizes myocardium to catecholamine - | Sevoflurane | Isoflurane | Ether | Halothane | 3d | single | Ans. is 'd' i.e., Halothaneo Some inhalational agent sensitize the heart to adrenaline -->>Arrhythmias can occur Therefore these agents are contraindicated in Pheochromocytoma and along with adrenaline.o Halothane has maximum propensity .o Other agents sensitizing the heart to adrenaline are Trilene, Cyclopropane, Chlo... | Anaesthesia | Miscellaneous General Anesthesia |
08231981-c129-4875-ac62-524833dca847 | First response to decreased blood volume | Increased hea rate | Tachypnea | Hypotension | Disorientation | 0a | single | Baroreceptor reflex is an immediate compensatory mechanism in shock. There is stimulation of aerial baroreceptors and so sympathetic output is increased leading to vasoconstriction and reflex tachycardia. Ref: Textbook of medical physiology by N Geetha, 2nd edition, page no. 184 | Physiology | Cardiovascular system |
3c368377-304c-4d85-a781-f4b7132c2fe3 | All are glands of eyelids EXCEPT: | Glands of zeis | Lacrimal gland | Meibomian gland | Glands of moll | 1b | multi | Ans. (b) Lacrimal glandRef: A.K. Khurana 6th ed. / 386GLANDS OF EYELIDS* Meibomian glands: Also known as tarsal glands present in the stroma of tarsal plate and are arranged vertically.# They are modified sebaceous glands. Their ducts open at the lid margin. Their secretion constitutes the oily layer of tear film.* Gla... | Ophthalmology | Anatomy |
c6205862-b3f2-45c9-a2dc-4adc8ccc9ebd | Crowding phenomenon is seen in: | Hypermetropia | Amblyopia | Strabismus | Retinitis pigmentosa | 1b | single | Crowding Phenomenon - patient is able to identify a Snellen chant character with the amblyopic eye when The character is presented in isolation. Crowding phenomenon seen in Amblyopia. Amblyopia - loss of vision in a child (<8yr) Lazy eye syndrome M/c/c of amblyopia = squint Best treatment of Amblyopia - occlusion of go... | Ophthalmology | Optics and Errors of Refraction |
3a63cae5-8a20-42b4-a58f-e3e68860d9f4 | Dull appearance of mouth temperature wax indicates | Insufficient material | Overextension | Contact of the material with tissues | Partial contact of tissues | 3d | single | null | Dental | null |
e36250c1-c8a1-45f4-974c-c57b5f992551 | All true about cephalosporins EXCEPT: | Ceftazimide is a 3rd generation cephalosporin | Cefoperzone has got antipseudomonal effect. | Cefoxitin has got no activity against anaerobes | Cephalosporins act by inhibiting cell wall synthesis | 2c | multi | This 2nd generation cephalosporin was developed subsequent to the first generation compounds and are more active against gram-negative organisms, anaerobes, but none inhibits P. aeruginosa ESSENTISLS OF MEDICAL PHARMACOLOGY | Pharmacology | Chemotherapy |
cad6a6e9-8334-442d-909a-03e00d891a94 | Which of the following is false about tympanic membrane: | Cone of light is antero-inferior | Shrapnell's membrane is also known as pars flaccida | Healed perforation has 3 layers | TM attachment to tip of malleus handle is called umbo | 2c | multi | (c) Healed perforation has 3 layers(Ref. Scott Brown, 8th ed., Vol 2; 529)The TM membrane which heals by itself does not have the fibrous layer. It has 2 layers only, the outer epithelial and the inner endothelial.Rest are true | ENT | Ear |
d4802899-bd30-4bb0-82aa-d6c71f236940 | Not true of Gall stones | Biliary fistula is a complication gall stone | More common in female | Clofibrate therapy is a predisposing factor | Ileal resection has no effect on gall stone formation | 3d | multi | Ans. (d) Ileal resection has no effect on gall stone formationRef: Sabiston 20th edition Page 1492 Gall stones:* Cholesterol stones are common in Ileal resection and in cases of Crohn's disease due to decreased Entero hepatic circulation and decreased Bile salts. | Surgery | Gall Bladder & Bile Ducts |
77843896-46a6-4353-aa9a-5eb5fd504dbc | All of them are true about the 4th nerve EXCEPT | The only nerve to emerge from the dorsal aspect of brain | The only nerve to cross over to opposite side | It is the thickest cranial nerve | It has the fewest axons of any cranial nerve | 2c | multi | The trochlear nerve has several features that make it unique from the other cranial nerves: Thinnest cranial nerve. Is the only nerve to exit from the dorsal surface of the brain. Is the only nerve in which all the lower motor neuron fibers decussate. Has the longest intracranial course. Has the smallest number of axon... | Ophthalmology | Neuro Ophthalmology |
f53fc939-e389-47b1-bf08-e6a916e1ec8a | Which of the following liners when exposed to oral fluids result in diminishment of their antimicrobial effectiveness? | MTA | Calcium hydroxide | Both | None | 2c | multi | MTA and calcium hydroxide undergo a transformation of hydroxide to calcium carbonate from exposure to carbon dioxide in the blood and oral fluids, causing their antimicrobial effectiveness to diminish. | Dental | null |
67bb78da-3e2b-4c2d-9f85-e09d48462f1f | Which of the following is the largest protein in the body that connects M line to Z line during active muscle contraction? | Actin | Desmin | Titin | All of above | 2c | multi | Ans. C. Titin. (Ref. Guyton & Hall's Textbook of Medical Physiology 11th/pg. 463)SarcomereThe portion of the myofibril (or of the whole muscle fiber) that lies between two successive Z discs is called a sarcomere. When the muscle fiber is contracted, the length of the sarcomere is about 2 micrometers. At this length, t... | Physiology | General |
a0a7ac1a-be54-48dd-9d35-aa53f7c58d5d | A 35-year old lady presented with dysphagia>> nocturnal asthma and weight loss for 6 years. The most probable diagnosis is - | Achalasia cardia | Lye stricture of esophagus | Gastroesophageal reflux diseae | Cancer esophagus | 0a | single | <P>Davidson&;s principles and practice of medicine 22nd edition #Achalasia cardia is presented with dysphagia ,episodic chest pain due to oesophageal spasm,nocturnal pulmonary aspiration, weight loss.</p> | Medicine | G.I.T |
9f817221-e452-4e07-8c68-b3da0d963908 | Radical neck dissection involves all except | Sternocleidomastoid muscle | Internal jugular vein | Vagus nerve | Spinal accessory nerve | 2c | multi | Vagus nerve is not removed in Radical Neck Dissection. Structures removed in Radical Neck Dissection: Level I-V Lymph nodes, Sternocleidomastoid, Internal Jugular Vein, Spinal Accessory Nerve, Submandibular salivary gland, Tail of parotid and Omohyoid muscle. Ref: Textbook of ENT, Dhingra; 6th edition; Pg no: 388 ref i... | ENT | Miscellaneous ENT |
eef1a8ed-b3be-4f9c-add6-d41157d2a092 | Which type of amyloidosis is caused by mutation of the transthyretin protein? | Familial Mediterranean fever | Familial amyloidotic polyneuropathy | Dialysis associated amyloidosis | Prion protein associated amyloidosis | 1b | single | Familial amyloid polyneuropathy (FAP) is phenotypically and genetically heterogeneous and is caused by mutations in the genes for transthyretin (TTR), apolipoprotein A1, or gelsolin. The majority of patients with FAP have mutations in the TTR gene. Amyloid deposition may be evident in abdominal fat pad, rectal, or nerv... | Pathology | null |
75fc64f0-d253-4ae4-aec7-2c4d2f70a444 | Most common cause of precipitation of renal failure in multiple myeloma is | Hyperurecemia | Infection | Hypercalcaemia | Amyloidosis | 2c | single | (C) Hypercalcaemia # Renal failure is seen in 25% patients and hypercalcaemia is the most common cause of renal failure.> Quite often renal failure develops rapidly even at an unchanged ratio of production and serum concentration of light chains. Various factors can favour renal cast formation in myeloma patients. Dehy... | Medicine | Miscellaneous |
451ab750-6028-441f-ac30-503e81a28784 | Presence of 1 up quark + 2 down quarks suggests the following: | Proton | Neutron | Electron | Positron | 1b | single | null | Radiology | null |
96419db9-e15f-48ed-9bcf-44f4c7a7f154 | Use of dexemditomidine ? | Prolong action of LA in hypeensive patients | Sedative agent for intubated patients | Increases bioavailability of regional anaesthetic drug | Helps in reducing bispectral index of general anaesthetic drug with low potency | 1b | single | Ans. is 'b' i.e., Sedative agent for intubated patients Dexmeditomidine It is a centrally acting a-2 adrenergic agonist It is approved by F.D.A. for sho term (<24 hours) continuous IV sedation of adults who are tracheally intubated. Its use as an anaesthetic agent is not recommended but it is useful in patients with br... | Anaesthesia | null |
b206f377-c0bd-4bb2-b4b2-f8a1fd00c583 | What is Kienboch's disease | Osteochondritis of lunate | Osteochondritis of neck of femur | Osteochondritis of navicular | Osteochondritis of tibial condyle | 0a | single | Ans. is 'a' i.e osteochondritis of lunate [Ref. : Maheshwari 3/e p269 (2/e, p268)JOsteochondritis :These are a group of miscellaneous affections of the growing epiphysis in children and adolescents.Typically, a bony nucleus of the epiphysis affected by osteochondritis becomes temporarily softened; and while in the soft... | Orthopaedics | Bone |
6a9c12aa-1156-4bbe-8393-bb26b3d40ba0 | Molar concentration of oral rehydration fluid is - | Sodium 30 meq | Potassium 20 meq | Bicarbonate 30 meq | Chloride 20 meq | 1b | single | Ans. is 'b' i.e., Potassium 20 meq | Pediatrics | null |
a788f2d5-a6b1-4850-ba74-ffeaa99852bf | Chronic thiazide therapy causes persistent hypercalcemia due to : | Renal tubular acidosis | Fanconi's syndrome | Hyper vitaminosis D | Hyper parathyroidism | 3d | single | Ans. is 'd' Hyperparathyroidism Chronic thiazide therapy causes hypercalcemia because it enhances the parathyroid mediated increase of Ca reabsorption.Note: Thiazide diuretics cause hypercalcemia where as high ceiling diuretics cause hypocalcemia.Other important side effects of Thiazide diureticsHyperuricemia *Hypokale... | Pharmacology | Diuretic |
c3357a81-a36a-4f75-86dd-5b405e8d741b | Methemoglobinemia is a complication following the administration of | Lignocaine | Lignocaine | Prilocaine | Procaine | 2c | single | null | Pharmacology | null |
b041942f-2b88-47a9-a68e-8cd47ab6bb8e | Cell of origin of hairy cell leukemia is - | B-cell | T-cell | NK-cell | Dendritic reticulum cell | 0a | single | Hairy cell leukaemia is an unusual & uncommon form of B cell malignancy characterized by presence of hairy cells in the blood & bone marrow & splenomegaly.Hairy cells are abnormal mononuclear cells with hairy cytoplasmic projections which are seen in blood,bone marrow & spleen.These cells exhibit CD19,CD20 & CD22 antig... | Medicine | Haematology |
4c7d439d-af00-4fea-8ae0-126fb1c23926 | Precautions advised after outpatient Radioiodine (I-131) therapy are all, EXCEPT: | Carry treatment ceificate for 90 days | To stay 2 meters away from children and pregnant women | Do not use household chlorine bleaches for cleaning | Use contraception for three months | 2c | multi | There is no such contraindication as do not use household chlorine bleaches for cleaning. Children and Pregnant Women: If there are pregnant women, infants, and children under 16 years of age in the home, arrangements should ensure that a distance >6 feet (or 2 meter) can be maintained between the patient and these occ... | Radiology | null |
cf6e51c0-56b0-43bd-bb8b-cbe81c23e7a0 | Patients with Antiphospholipid antibodies may manifest with any of the following, except: | Venous thrombosis | Aerial Thrombosis | Hemolytic Anemia | Thrombocytosis | 3d | multi | Answer is D (Thrombocytosis): Refer Review Notes on Antiphospholipid Syndrome Antiphospholipid Antibody Syndrome is associated with thrombocytopenia and not thrombocytosis. The presence of thrombocytopenia does not appear to reduce thrombotic risk in patients with APS. Recurrent aerial or venous thrombosis in any tissu... | Medicine | null |
36b0eb58-51f6-4841-bcfb-f90941092730 | Which irrigating solution has tissue dissolving properties | EDTA | Sodium Hypochlorite | Saline | Citric Acid | 1b | single | null | Dental | null |
8b003a69-0154-4361-bba6-f168f1d9fdc6 | Which of the following enzymes is used in Recombinant DNA research for Homopolymer tailing | Reverse transcriptase | S1 Transferase | Polynucleotide kinase | Terminal transferase | 3d | single | Terminaldeoxynucleotidyltransferase catalyzes the addition of deoxynucleotides to the 3' termini of DNA. ... By use of a tailing method, which adds homopolymerdeoxynucleotide tails to denatured DNA, any double-stranded DNA fragment can be joined to a cloning vehicle Ref biochemistry satyanarayana 4e p255 | Biochemistry | Structure and function of protein |
374476b9-8b07-45d8-85db-c0b072d7517a | Hardness number which does not depend on the ductility of metal: | KHN | VHN | RHN | BHN | 0a | single | KNOOP HARDNESS TEST (KHN)
A diamond indenting tool is used. Knoop hardness values is independent of the ductility of the material and values for both exceedingly hard and soft materials can be obtained from this test. The Knoop and Vickers tests are classified as microhardness tests. The Brinell and Rockwell tests are ... | Dental | null |
70fa5cb8-fa40-414d-8d91-49c59b69aa52 | Most abundant complement in the body | C1 | C2 | C3 | C4 | 2c | single | C3 is the most abundant complement. | Microbiology | null |
95253b3b-1d0d-4c4d-b6ef-665fef41468f | Use of oral contraceptives decreases the incidence of all of the following except: | Ectopic pregnancy | Epithelial ovarian malignancy | Hepatic adenoma | Pelvic inflammatory disease | 2c | multi | null | Gynaecology & Obstetrics | null |
e09ccfa9-aea7-4ffc-82d3-5c87fd9e1d81 | Which of the following is not formed sphincter of oddi complex? | Sphincter pancreaticus | Sphincter ampullae | Superior choledochal sphincter | Posterior choledochal sphincter | 3d | single | Sphincter of oddi complex:- 1. sphincter ampullae 2. sphincter pancreaticus 3. superior choledochal sphincter 4. inferior choledochal sphincter | Surgery | Bile duct |
029aea24-7c95-4c73-ad95-f73d65231540 | Disorders associated with vitiligo EXCEPT? | Androgenic Alopecia | Hypothyroidism | Addison's disease | Diabetes mellitus | 0a | multi | DISORDERS ASSOCIATED WITH VITILIGO Thyroid disease: Hypehyroidism Hypothyroidism Pernicious anemia Addison's disease Diabetes mellitus Hypoparathyroidism Myasthenia gravis Alopecia areata Morphoea and lichen sclerosis | Dental | Hypo Pigmentary Disorders |
ac5ec918-1927-4435-b578-9828e512ab6a | True signs of placental separation are all of the following. except? | Fresh bleeding per vaginum | Firm Fundus | Permanent Lengthening of umblical cord | Round flabby uterus | 3d | multi | Signs of placental separation Lengthening of cord A gush of fresh bleeding Suprapubic bulge, due to firm uterine fundus after placental separation, is the most specific sign A Flabby uterus means that the placenta is still probably stuck to the uterus and hence preventing its proper contraction | Gynaecology & Obstetrics | Placenta - Types and their complications |
d1558bab-94ad-4fac-95c5-aa2bf7cf5325 | A 12 year old girl presents with a 0.4 cm slightly raised strawberry coloured nodule in the skin of the abdomen below the umbilicus. It is present for many years and not changed in color or size. Diagnosis | Carcinoma | Melanoma | Hemangioma | Lymphoma | 2c | single | Answer: c) Hemangioma (ROBBINS 9th ED, P-516)HEMANGIOMAHemangiomas are very common tumors characterized by increased numbers of normal or abnormal vessels filled with bloodMost are present from birth and initially increase in size, but many eventually regress spontaneouslyWhile hemangiomas typically are localized lesio... | Surgery | Neoplasia |
769f1667-dd2a-46a8-888b-13346df77ed6 | The following methods can be used to detect the point mutation in the beta (β)-globin gene that causes sickle cell anemia, except - | Polymerase chain reaction with allele-specific oligonucleotide hybridization | Southern blot analysis | DNA sequencing | Northern blot analysis | 3d | multi | To detect point mutation, DNA analysis is required. While northern blot is a test for study of RNA.
Polymerase chain reaction, DNA sequencing and southern blot testing are rapid methods for DNA analysis, and can all be used to detect the point mutation in the globin gene. | Biochemistry | null |
8a334eb2-2f8d-4220-8530-a0c9eb456276 | Treatment of choice for vocal nodule is | Radical excision | Microlaryngoscopic removal | Cryotherapy | Wait and watch | 1b | single | Treatment of vocal nodules Early cases of vocal nodules can be treated conservatively by educating the patient about the proper use of voice. With this treatment, many nodules in children disappear completely. Surgery is required for large nodules or nodules of long standing in adults. They are excised with precision u... | ENT | Larynx |
17dadaee-6072-4e3c-a0da-aba846929e95 | When selecting the colour of cement to use for cementing a porcelain jacket crown, the powder being tested is best mixed with: | Glycerin-water solution | Cement liquid | Alcohol | Only water | 0a | single | Self-cured and dual-cured materials can be opaque or translucent, and those indicated for cementation of ceramic restorations are usually provided in several shades. Light-cured materials are indicated for bonding of laminated ceramic veneers (esthetic cements) or orthodontic brackets. Some esthetic resin cements used ... | Dental | null |
02fada54-151d-4b6a-943d-c739b289be16 | Schneider's 1st rank symptoms seen in | Delusion | Hallucination | Schizoid personality | Schizophrenia | 3d | multi | Ku Schneider (1959) described symptoms which, though not specific to schizophrenia, were of great help in making a clinical diagnosis of schizophrenia. These are popularly called as Schneider's first-rank symptoms of schizophrenia (FRS or SFRS). He also described the second rank symptoms of schizophrenia (which were co... | Psychiatry | Schizophrenia and other psychotic disorders |
58c3c98a-2205-491d-a082-e413f1e29dc0 | Moth eaten alopecia is seen with - | Leprosy | Syphilis | Fungal infection | Cylindroma | 1b | single | Ans. is 'b' i.e., Syphilis | Surgery | null |
a6817d4c-51a9-4403-a5e3-bbd9b2422d60 | Community diagnosis means | Quantifying and summarizing the impoant health problems and their associated sociodemographic characteristic in a community | Priority - wise listing of the common diseases seen in a community | Summarizing the standards of living lifestyle factors in a community | None of the above | 0a | multi | Community diagnosis refers to identification and quantification of health problems in a community in terms of moality and morbidity rates and ratios, and identification of their correlates for the purpose of defining those individuals or groups at risk or those in need of healthcare.Park 23e pg: 91 | Social & Preventive Medicine | Epidemiology |
8c405512-3ca4-4538-bacb-c15e0050eb7a | A 2-year-old child with history of fall one year back with parietal bone fracture now presented with painful and growing parietal swelling. | Growing scalp hematoma | Growing fracture | Subdural hygroma | Chronic abscess | 1b | multi | (b) Growing fracture,Ref: Growing skull fractures: classification and management. Naim-Ur-Rahman et al Br J Neurosurg. (1994)Growing Fractures:* Also known as traumatic encephaloceles or leptomeningeal cysts* Skull fractures associated with an underlying dural tear may fail to heal properly.* Enlargement of the defect ... | Pediatrics | Gastro Intestinal System |
40976304-978e-4ea9-99a3-d64c3542d037 | Non specific esterase is positive in all the categories of AML except - | M3 | M4 | M5 | M6 | 3d | multi | Ans. is 'd' i.e., M6 o FAB classification divides AML into eight types M 0 to M7. o This scheme takes into account : ? i) The degree of maturation (MO to M3) ii) The lineage of leukemic blast (M4 to M7). Class Blast cells o Myeloperoxidase negative Mo minimally differentiatedAML o Auer rods negative o Express myeloid l... | Pediatrics | null |
d212f837-ea72-4809-ab4e-a0629006bc1a | NOT a content of superior mediastinum | Pulmonary trunk | Thymus | Left superior intercostal aery | Arch of aoa | 0a | single | Mediastinum refers to the space between two lungs in thorax. SUPERIOR MEDIASTINUM Space above 2nd costal cailage CONTENTS: thymus, arch of aoa, superior venacava, pulmonary aeries, esophagus, trachea, T1 - T4 veebra, PICA - 1, 2. INFERIOR MEDIASTINUM Space below superior mediastinum, again divided into anterior, middle... | Anatomy | FMGE 2017 |
c8444346-2705-4da1-9c98-26249210a998 | A10-year-old girl present with polyuria and polydipsia with hypokalemia, hypercalciuria and metabolic alkalosis. What is the probable diagnosis? | Gitelmann syndrome | Liddle syndrome | Bartter syndrome | Alport's syndrome | 2c | single | Ans: (c) Bartter syndromeRef: Nelson Textbook of Pediatrics, 20th edition, Page 2534BARTTER SYNDROME (AUTOSOMAL RECESSIVE)Clinical Subtypes:Antenatal Bartter syndrome (Hyperprostaglandin E syndrome):Mutations-genes that encode the sodium potassium 2 chloride transporter NKCC2 (the site of action of furosemide) orThe lu... | Pediatrics | Kidney |
24806071-74e0-4121-85de-ff5dde9776a0 | Best antagonist of morphine is – | Nalorphine | Naloxone | Buprenorphine | Pentazocine | 1b | single | Naloxone is the preferred specific antidote for morphine poisoning. | Anaesthesia | null |
606641be-d4d9-49d8-860d-91f198d9de5a | Filigree burns occur in ? | Lightening | Electrocution | Vitrilage | Infanticide | 0a | single | Ans. is 'a' i.e., Lightening Lightening burns Lightening refers to discharge of current between a negatively charged cloud and positively charged aicle on eah. During lightening, injuries result due to following mechanisms :- Direct effect of high voltage current. Heat, i.e. super heated air causing burns. Expanded and... | Forensic Medicine | null |
3b2e0a44-2112-4cef-b514-cb60c30579fe | The most common cause for chronic cor pulmonale is | Recurrent pulmonary embolization | COPD | Cystic fibrosis | Bronchial Asthma | 1b | single | Answer is B (COPD): The most common cause of chronic cor puhnonale is chronic. obstructive pulmonary disease - Rubin's pathology | Medicine | null |
49071582-b833-4afc-9107-7056ee5ac110 | A 75-year-old thin cachectic woman undergoes a tracheostomy for failure to wean from the ventilator. One week later, she develops significant bleeding from the tracheostomy. Which of the following would be an appropriate initial step in the management of this problem? | Remove the tracheostomy and place pressure over the wound. | Deflate the balloon cuff on the tracheostomy. | Attempt to reintubate the patient with an endotracheal tube | Upsize the tracheostomy | 2c | multi | The patient had a sentinel bleed from a tracheoinnominate aery fistula, which carries a greater than 50% moality rate. If the bleeding has ceased, then immediate fiberoptic exploration in the operating room is indicated. If the bleeding is ongoing, several stopgap measures can be attempted while preparing for median st... | Anaesthesia | Miscellaneous |
2fe65856-520a-4e00-8420-9cc2f9fa1f53 | A Sentinel pile indicates | Internal hemorrhoids | Pilonidal sinus | Fissure in ano | Fistula in ano | 2c | single | Ans. c (Fissure in ano) (Ref. Bailey and Love Surgery 26th/1250; Ref. Q. 216 of MH-2007).SENTINEL PILE- This misnomer is given to a skin tag marking--and often containing within it--the distal end of an anal fissure, found usually in the posterior midline. | Surgery | Anal Fissures |
e209dd0e-f3da-4b43-84a4-b03dbdd375c7 | Which of the following is not characteristic of visceral pain - | Poor localisation | Diffuse in nature | High threshold | Very rapid adaptation | 3d | single | • Visceral pain is poorly localized, often the pain is referred or radiating
• Pain of hollow viscus is often felt as a colic (it comes and goes to reappear again).
• Highly localized types of damage to the viscera seldom cause severe pain
• Often accompanied by vomiting and hypotension | Surgery | null |
621ed0e9-3152-4e80-9250-1f60f8157c68 | Hanup disease, limiting amino acid | Tyrosine | Tryptophan | Rhenylalanine | None | 1b | multi | It&;s an autosomal recessive disease. Absorption of aromatic amino acids from intestine as well as reabsorption from renal tubules are defective Patient improve when put on high protein diet with supplementation of niacin Hence the limiting amino acid is tryptophanRef: DM Vasudevan - Textbook of Biochemistry, 7th editi... | Biochemistry | Metabolism of protein and amino acid |
9c7ed8a1-5210-4c7a-b069-bd657d5b7f14 | All of the following statements about Lymphoepethelioma of the parotid gland are true, except: | Parotid gland is the most common site of Lymphoepethelioma in the Head & Neck region | It is associated with EBV infection | It is highly radiosensitive malignancy | It is a squamous cell carcinoma | 0a | multi | Lymphoepithelioma occur chiefly in the nasopharynx of young or middle aged persons. It also seen in the oropharynx, tongue, tonsil, parotid, nasal chamber and paranasal sinus. Ref: Shafer'S Textbook of Oral Pathology By Rajendran, 6th Edition, Pages 119-120; Epstein-Barr Virus By Erle S. Robeson, Page 60 | Surgery | null |
505b1349-ff1c-4f9a-bd40-899cc6f5e4f9 | Which of the following structure is not present in the transpyloric plane? | First lumbar vertebra | Fundus of gall bladder | Hilum of right kidney | Inferior mesenteric vein | 3d | multi | Transpyloric plane- An imaginary plane that passes at the lower border of L1 vertebra posteriorly and the tip of 9th costal cartilage anteriorly.
Structures at the Transpyloric plane
- Pylorus of stomach
- Hilum of kidney
- Beginning of duodenum
- Neck of pancreas
- Fundus of gallblad... | Anatomy | null |
f9aaa62f-8d57-4c38-8c84-10d42d216f9c | Most common benign tumour of the stomach is ? | Adenoma | Lipoma | Hamaoma | Leiomyoma | 0a | single | Ans. is 'a' i.e., Adenoma E ihtelial nolvus are the most common benign tumor of the stomach. They are of 5 types: a) Hyperplastic (regenerative) most common type (75%), with low malignant potential b) Adenomatous second most common, with high malignant potential (should be removed when diagnosed) c) Hamaomatous d) Infl... | Surgery | null |
8319effe-78c9-4d3f-9638-296bb6dbbdc6 | All are true regarding myositis ossificans progressive except | Usually involve childs | Progressive form of normal myositis | Respiratory problems | Ankylosis | 1b | multi | B i.e. Progressive form of normal myosites Fibrodysplasia (Myositis) Ossificans Progressiva Patho Histology - It is a rare autosomal dominant (AD) disorder of connective tissue differentiation. - Main pathogenic mechanism is defective regulation of the induction of endochondral ossification - Intense perivascular lymph... | Surgery | null |
a79e7ed3-a6b8-4933-bbb6-bece2f0fee4a | Meningococcal polyvalent vaccine is routinely recommended to: | Adolescents young males | All healthy children between 5-7 years of age | More than 50 years of age diabetic patients on regular insulin | 40 years old paramedical staff working in laboratory | 1b | multi | Ans. b. All healthy children between 5-7 years of age (Ref: Park 23/e p166, 22/e p157)'Quadrivalent (polyvalent) vaccines are administered as a single dose to individuals aged >_ 2 years.'- Park 22/e p157Meningococcal VaccinesPolysaccharide VaccinesConjugate Vaccines* Available against Meningococci of serogroup A, C, W... | Social & Preventive Medicine | Meningococcal Meningitis |
69623aa4-fcd6-4514-aba4-2992aa6a2dc6 | Drug not causing exatithematous skin eruption – | Phenytoin | Hydrocortisone | Ampicillin | Phenylbutazone | 1b | single | Drugs causing exanthematic reactions
Most common : - Ampicillin and penicillin, Phenylbutazone and other pyrazolones, Sulphonamides, Phenytoin,
Carbamazepine, Gold, Gentamicin, Meprobamate, Atropine
Less common : - Cephalosporins, Barbiturates, Thiazides, Naproxen, Isoniazid, Phenothiazines, Quinidine. | Dental | null |
d2922f51-5dda-4bf4-91ef-ab9e2cd3b182 | A 34-year-old woman is seen in the emergency depament. About 5 hours previously, she began to have nausea, vomiting, abdominal cramps, and diarrhea. She then developed double vision, which prompted her to ask her husband to bring her to the emergency depament. When she is asked to go into the examining room, she stumbl... | Clostridium botulinum | Clostridium perfringens | Clostridium ramosum | Clostridium septicum | 0a | single | This is a typical presentation of botulism, which is caused by the preformed toxin of Clostridium botulinum. Patients develop a progressive flaccid paralysis that can lead to death if their respiratory system is not adequately suppoed. Mentation is intact in these patients, and they do not exhibit sensory changes excep... | Microbiology | null |
8ec86a6a-5148-4dc4-ac54-44d96da6323c | The rectum measures | 18 cm | 22 cm | 17 cm | 15 cm | 3d | single | The adult rectum is approximately 12-18 cm in length and is conveniently divided into three equal pas: the upper third, which is mobile and has a peritoneal coat; the middle third where the peritoneum covers only the anterior and pa of the lateral surfaces; and the lowest third, which lies deep in the pelvis surrounded... | Surgery | G.I.T |
0569ce46-9396-4e0d-94fc-e9fd04e6cca2 | Tardy ulnar neuritis may be due to | Advanced osteo ahritis of elbow | Cubitus valgus deformity | Both of the above | None of the above | 1b | multi | B i.e. Cubitus valgus deformity | Surgery | null |
4cd7d75c-214e-4e39-a6a5-076af6b5de7e | Which of the following can be a homologous substitution for valine in hemoglobin | Isoleucine | Glutamic acid | Phenylalanine | Lysine | 1b | single | null | Biochemistry | null |
ef463d47-ed9b-45a3-a776-1dc18fc1d685 | Hemorrhagic cystitis is caused by : | Cyclophosphamide | 6 Mercaptopurine | 5 Fluorouracil | Busulfan | 0a | single | Cyclophosphamide is a prodrug and is activated by hepatic biotransformation to aldophosphamide. One of its degradation products is acrolein that is responsible for hemorrhagic cystitis (its characteristic adverse effect). This adverse effect can be decreased by vigorous hydration and by the use of mercapto ethane sulf... | Pharmacology | null |
f3e59204-457d-4011-87b1-36516fb4df3b | In myasthenia gravis , all of the following are true except | Women are more frequently affected than men | Bulbar weakness is especially prominent inMuSK antibody- positive myasthenia gravis. | Unrelated infections or systemic disorders can lead to increased myasthenic weakness | Tongue muscles are spared | 3d | multi | Overall, women are affected more frequently than men, in a ratio of ~3:2. The cardinal features are weakness and fatigability of muscles. The weakness increases during repeated use (fatigue) or late in the day and may improve following rest or sleep. Unrelated infections or systemic disorders can lead to increased myas... | Medicine | C.N.S |
258afd55-3f4f-4258-afbc-3d9036965294 | Factor IX deficiency results in increased - | PT (Prothrombin Time) | PTT (Partial thromboplastin time) | BT (Bleeding Time) | TT (Thrombin time) | 1b | single | Ans. is 'b' i.e., PTT (Partial thromboplastin time) o Partial thromboplastin time (PTT): It tests the intrinsic and common coagulation pathways. So, a prolonged PTT can results from deficiency of factor V, VIII (factor VIIIc, Von willebrand factor), IX, X, XI, XII, prothrombin or fibrinogen.o Prothrombin time (PT): It ... | Pathology | Bleeding Disorders |
25d04c1f-db76-43d7-81d6-3d43525c4ab1 | All of the following can be done with Individual as a unit except | Drug administration | Health education | Vaccination | Case report | 1b | multi | Health education can be done individually BUT limitation is that the numbers we reach is really small, and health education is given to only those who come in contact with health system. | Social & Preventive Medicine | null |
dc41df5b-b907-40f8-bbb6-9af859f92145 | Precursor of norepinephrine - | Tryptophan | Tyrosine | Methionine | Asparagine | 1b | single | Ans. is 'b' i.e.. Tyrosine | Biochemistry | Miscellaneous (Structure & Function of Proteins) |
c1ed59db-4fb8-4dd6-8f27-56a765ef7ca8 | Persistent foetal lobulation of adult kidney is due to | Congenital renal defect | Obstructive uropathy | Intrauterine infections and scar | Is a normal variant | 3d | single | In humans, embryologically, the kidneys originate as distinct lobules that fuse as they develop and grow. The lobulation of the fetal kidney is usually lost as the lobules become bonded together by the growth of new coex and the renal capsule. Persistent fetal lobulation is a normal variant seen occasionally in adult k... | Surgery | Urology |
edf4875a-78ac-46fd-993a-e1af3df77cd8 | CMV retinitis in HIV occurs when teh CD4 counts falls below - | 50 | 100 | 200 | 150 | 1b | multi | CD4 count<100 cells/mm3 REF:<\p> MICROBIOLOGY ANANTHA NARAYANAN NINTH EDITION PAGE.473 case-3 | Microbiology | Virology |
40aeabaa-c021-4196-a644-a4134a6665c8 | Drop metastases is seen in | Medulloblastoma | Ependymoma | Cerebellar astrocytoma | Neuroblastoma | 0a | single | Drop metastases - Dissemination through CSF giving rise to nodular masses at some distance from primary tumour. It is seen in Medulloblastoma | Pediatrics | null |
480e7f93-b827-419f-b60b-7fdcc619fb6c | Intra epidermal Bulla is seen in : | Pemphigoid | Pemphigus | Dermatitis Herpetiformis | Light reaction | 1b | single | Ans. is 'b' Pemphigus "Pemphigus causes intraepidermal blistering because of loosening of desm somal links b/w epidermal cells caused by immunological attack- Roxburg, 16/e | Skin | Pemphigoid Group |
a8f94c80-04ea-4319-bb88-c28d33a26269 | A young patient has a midline, tender swelling in neck occurring after an attack of sore throat. The diagnosis is - | Acute thyroiditis | Thyroglossal cyst | Sub acute thyroiditis | Toxic goiter | 2c | single | Diagnosis in this case is subacute thyroiditis. Symptoms are more severe in acute thyroiditis with complications and acute thyroiditis is more common in children.
Just take a look of acute thyroiditis.
• Acute thyroiditis is rare and due to suppurative infection of the thyroid.
• More common in children and often is pr... | Surgery | null |
e2994055-53ec-4b2e-b14b-ed9faa704209 | Delorme's operation is for | Solitary rectal ulcer | Rectal prolapse | Rectal stricture | Rectal carcinoma | 1b | single | Ans. B. Rectal prolapse. (Ref. LB 25th pg. 1225)RECTALPROPLASE# It may be mucosal or full thickness (whole wall included).# Commences as rectal intussusception.# In children, the prolapse is usually mucosal an should be Rxed conservatively.# In the adults, the prolapse is often full thickness and is frequently asociate... | Surgery | Rectum |
b1444c09-3fa6-47dc-a3c5-7ecc5e1c5df9 | All of the following are true about Hepcidin except | It is a 25- amino acid peptide secreted by Kupffer cells | Decreases duodenal absorption of iron | It regulates activity of transpoers DMT - 1 and ferropoin - 1 | Mice with enhanced hepcidin expression have elevate body iron stores | 3d | multi | Hepcidin, a 25-amino acid peptide secreted by hepatic Kupffer's cells downregulates duodenal iron absorption by regulating DMT1 activity as well as other proteins in the iron-responsive pathways (e.g., FP1). Hepcidin is a negative regulator of iron absorption because mice that fail to express hepcidin have elevated bod... | Physiology | General physiology |
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