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135
e2134e1c-a419-472f-86f8-20f0500ad1eb
Management plan for osteogenic sarcoma of the lower end of femur must include:
Surgery alone
Chemotherapy + radiotherapy
Radiotherapy + amputation+ chemotherapy
Chemotherapy + Limb Salvage Surgery
3d
single
The usual approach in the treatment of osteosarcoma includes surgery and chemotherapy. The most frequently used effective chemotherapy agents include high-dose methotrexate, doxorubicin, cisplatin, and ifosfamide or etoposide. Radiotherapy does not play a role in the treatment of osteosarcoma as these cells are not rad...
Surgery
null
bae5d9e2-2c8f-4524-8b78-13384b32f64e
At what cervical level spinal cord circumference is maximum?
C4
C5
C6
C7
2c
single
Maximum spinal cord circumference is at level c6 BD CHAURASIA S HUMAN ANATOMY Vol1
Anatomy
General anatomy
9dbd2361-c71e-4365-96af-b57b265da946
A newborn is prone for hypothermia due to following reasons except?
More body surface area
Less subcutaneous fat
Larger head size compared to rest of body
Brown fat
3d
multi
Presence of brown fat is a protective mechanism against hypothermia in newborn babies Infants have more body surface area compared to adults which makes them prone for heat loss. In paicular, head size has the largest body surface area in the entire body In low bihweight and preterm infants, the insulatinglayer of subc...
Pediatrics
Neonatal hypothermia
7197f6f2-eff8-48bf-81fa-f4d9eb88f692
Traumatic fracture showing avascular necrosis: (PGI Dec 2007)
Femoral neck
Surgical neck of humerus
Body of talus
Cuboid
0a
single
Ans. A (Femoral neck) /Ref: Maheswari 3td/40-41,270; Dahnert Radiology Review manual 5th/46-48; Chapman 4th/45-46; Apley 8th/570-571]Avascular necrosis is common in fracture of- femoral neckQ (including slipped capital femoral epiphysis(r), posterior dislocation of hip}, neck talus(r), waist scaphoid(r) & lunateQ (disl...
Orthopaedics
Avascular Necrosis
8d5ac53b-faf3-426f-a10f-fc892d01abd9
True about fourth heart sound is
Occurs at end of P wave in ECG
Occurs at end of T wave in ECG
Occurs during early rapid filling phase of ventricular diastole
Occurs during slow ejection phase of Ventricular systole
0a
multi
null
Physiology
null
025ab57f-f74c-418e-9211-63a4036c7038
A new test to measure B.P has successive reading of same person as follow: 110/70 mmHg, 128/80 mmHg, 132/70 mmHg, 160/90 mmHg. The given test has, when mean B.P =120/80mmHg.
Low validity, Low reliability
Low validity, high reliability
High validity, low reliability
High validity, high reliability
0a
single
null
Social & Preventive Medicine
null
a2be9d60-9b0b-4ffd-b7cb-f74a53922e75
Common variable deficiency is due to -
Absent B cells
Reduced number of B cells
Defective B cell differentiation
All of the above
2c
multi
Most patients with common variable immunodeficiency have normal or near-normal numbers of B cells in the blood and lymphoid tissues. These B cells, however, are not able to differentiate into plasma cells. The clinical manifestations are caused by antibody deficiency. The feature common to all patients is hypogammaglob...
Pathology
null
d658aff5-1518-40f9-9229-6c577b251f83
All are associated with paraneoplastic syndromes except -
Cerebeller degeneration
Progressive multifocal leucoencephalopathy
Amyotropic lateral sclerosis
Opsoclonus myoclonus
1b
multi
null
Medicine
null
a1f3cb33-914c-4069-9b11-71f97dcb1308
The efferent limb of a myotatic reflex includes a(n):
Anterior horn motor neuron
Lateral horn visceromotor nucleus.
Muscle spindle.
Preganglionic sympathetic neuron
0a
single
The myotatic reflex is a monosynaptic, sretch reflex. The efferent limb consists of the axon of an anterior horn alpha motor neuron that innervates striated muscle fibers (effector). The afferent limb consists of a muscle spindle (receptor) and an Ia fiber (axon) of a spinal ganglion neuron.
Physiology
Motor System
369feed3-a8cf-49da-bfe2-52f245d89573
Ivabridine is indicated in the management of
PSVT
Angina pectoris
Cardiomyopathy
Irritable bowel syndrome
1b
single
Refer kDT 6/e p 55,katzung 11e p203 Ivabradine is a bradycardia drug. It selectively blocks if sodium channel blocker and reduce hea rate by inhibiting the hyperpolarization activated sodium channel in the SA node. No other significant hemodynamic effects has been noted. It reduces and then attacked similar to Calcium ...
Pharmacology
Cardiovascular system
f32fa11d-f466-4282-9777-c12122e74911
Shape of nulliparous cervical canal is :
Circular
Transverse
Spherical
Longitudinal
1b
single
Transverse [Ref: BDC 4/e, Vol 2, p 359; Gray's Anatomy 38/e, p 1871; Jeffcoate's Gynaecology 6/e, p 31 Don't get confused with the answer . Question is about cervical canal & not the external os. The external os is circular in a nulliparous woman & transverse or slit like in parous women. In a nulliparous women, the ce...
Forensic Medicine
null
37a92bb5-67ba-4f1d-8735-8aa38e00ff76
Which of the following nerves are affected after spinal anesthetic block
Motor and sensory only
Sensory and autonomic nerve only
Sensory nerves only
Sensory autonomic and motor nerves
3d
single
Spinal anesthetic block affect sensory autonomic and motor nerve
Anaesthesia
Regional anaesthesia
6ff7f1f1-7c34-4e7a-b8fe-6d7cdf9a4214
The UK refinement of Hannifin and Rajka criteria is used in the diagnosis of ____:
Atopic dermatitis
Nummular Eczema
Eczema Herpeticum
Contact dermatitis
0a
single
Ans. A. Atopic dermatitis* The UK refinement of Hannifin and Rajka criteria is used in the diagnosis of Atopic dermatitis.* The original Hannifin and Rajka criteria requires that patients have at least 3 of the 4 major criteria and 3 of the 23 minor criteria.* Consequently, Williams et al coordinated a UK working party...
Skin
Dermatitis Erythema
b25c38f6-e3b1-4112-8488-ca0f99b6a585
Codfish veebrae are seen in: March 2004
Osteopetrosis
Osteoporosis
Morquis syndrome
All of the above
1b
multi
Ans. B i.e. Osteoporosis
Surgery
null
a55ca1b8-cc03-4a51-a78d-49c8a52f1797
According to IAP classification of Grade IV malnutrition, Weight-for-age of the standard (%) is _________
71-80
61-70
51-60
< 50
3d
single
IAP classification of malnutrition Grade of malnutrition Weight-for-age of the standard (%) Normal >80 Grade I 71-80 (mild malnutrition) Grade II 61-70 (moderate malnutrition) Grade III 51-60 (severe malnutrition) Grade IV <50 (very severe malnutrition) Reference: Paediatrics; O.P Ghai; 8th edition; Page no: 97
Pediatrics
Nutrition
1325c5ff-553b-4dc6-9478-14b26206e9e3
The ketolide which retain activity against streptococcus pneumoniae that are resistant to macrolide is:
Telithromycin
Quinupristin
Lincomycin
Dalfopristin
0a
single
Telithromycin is useful in the setting of streptococcal pneumonia that is resistant to macrolide Ref: Harrisons, Edition-18, Page : 1138.
Medicine
null
6d2eeaa7-954a-4d75-ad27-a0a258b09590
indications of FESS:
Inveed papilloma
Orbital abscess
Nasal polyposis
All
3d
multi
Ans. is all [indications of Function) endoscopic Endoscopic Surgery (FESS) Nasal conditions: Indian = Inflammation of sinus (sinusitis - chronic and fungal) Prime = Polyp removal Minister = Mucocelea of frontal and ethmoid sinus Can = Choanal atresia repair Speak = Septoplasty Fluent = Foreign body removal English = Ep...
ENT
null
04c6ad9b-5668-41bc-b4e3-901dbbfd6947
HbA, AC level in blood explains -
Acute rise of sugar
Long terms status of blood sugar
Hepatorenal syndrome
Chronic pancreatitis
1b
single
null
Medicine
null
f32952db-07e6-4160-91e2-cc86b3147f3b
Hypersensitivity vasculitisis seen most commonly in
Post capillary venules
Arterioles
Veins
Capillaries
0a
single
HYPERSENSITIVITY VASCULITIS In hypersensitivity vasuculitis, postcapillaryvenules are the most commonly involved vessels, capillaries and arterioles are involved less frequently. It is primarily a disease of small vessels. It is characterized by leukocytoclasis, a term that refers to the nuclear debris remaining from t...
Unknown
null
5ef25e98-1620-4003-9f4d-933b0e12889e
Which anterior will have 2nd root most commonly
Lower Canine
Lower Lateral Incisor
Upper canine
Upper Lateral incisor
0a
single
null
Dental
null
ab81ce5e-ccdb-49ac-af0f-8f73888767e9
The parvocellular pathway, from the lateral geniculate nucleus to the visual coex, carries signals for the detection of:
Movement, depth and flicker
Color vision, shape and fine details
Temporal frequency
Luminance contrast
1b
single
B i.e. Colour vision, shape, fine details 'The parvocellular pathway from layers 3-6 carries signals for colour vision, textures, shape and fine detail'.
Ophthalmology
null
f89e596c-23d7-454e-b9f7-2b7270f62aac
Trench fever is caused by -
Bartonella Quintana
Coxiella burnetii
Rickettsia akari
Rickettsia conori
0a
single
Ans. is 'a' i.e., Bartonella Quintana * Trench fever, also called 5-day fever or quintan fever, is caused by Bartonella quintana (Rochalimaea quintana).* The human body louce (Pediculus humans corporis) is the vector and humans is the only known reservoir.
Microbiology
Bacteria
b7218254-2d63-4ff1-abff-63b696f0ed9c
All are causes of Osteoporosis, except:
Thyrotoxicosis
Hypothyroidism
Chronic heparin therapy
Old age
1b
multi
Answer is B (Hypothyroidism) Osteoporosis is seen with hypehyroidism and not with hypothyroidism. Chronic heparin therapy, thyrotoxicosis and old age are all causes of osteoporosis
Medicine
null
cbdc7583-1f75-4e9e-82c8-59c5bf2d9bac
Positive Rinne indicates
AC>BC
BC>AC
BC=AC
None of the above
0a
multi
Positive Rinne`s test- AC>BC (Normal hearing, Sensorineural Hearing loss)Negative Rinne`s test- BC>AC (Conductive Hearing loss)False negative Rinne`s- Severe unilateral Sensorineural Hearing lossRef: Hazarika; 3rd ed; Pg 53
ENT
Ear
c3835a9c-5206-4195-a002-1a532ca51b85
Regurgitation of food back from stomach into oesophagus is prevented by
Pinch cock effect of diaphragm
Negative intrathoracic pressure
Oesophagogastric angle
All of the above
3d
multi
Regurgitation of food back from stomach into oesophagus is prevented by: (i) tone of gastro-oesophageal sphincter, (ii) negative intrathoracic pressure, (iii) pinch-cock effect of diaphragm, (iv) mucosal folds, (v) oesophagogastric angle and (vi) slightly positive intra-abdominal pressure. Ref:- Dhingra; pg num:-341
ENT
Oral cavity & Oesophagus
00317043-92c0-49bc-9835-414fe4544f83
Dental papilla give rise to ?
Enamel
Dental cuticle
Tooth pulp
None
2c
multi
Ans. is 'c' i.e., Tooth pulp The mesenchymal cell's of dental papillae forms : Odontoblasts which form dentine Tooth pulp
Anatomy
null
0952901d-19bc-4078-b4d7-c600208c86f9
Thrombophlebitis extending from thigh to involve iliofemoral vein causes
Red leg
Blue leg
Purple leg
White leg
3d
single
Answer- D. White legWhite leg (Phlegmasia alba dolens)- seen in ileofemoral thrombophlebitis.Phlegmasia alba dolens (white leg): This is characterised by aerial spasm resulting in pale, cold leg with diminished pulses, with blanching of the limb, more often seen in iliofemoral thrombophlebitis and is called milk leg of...
Surgery
null
6344b226-4a03-4c55-8a53-def29f5690d1
Burkitt&;s lymphoma shows which translocation?
8:14
9:22
11:14
14:18
0a
single
All forms of Burkitt lymphoma are highly associated with translocation of MYC gene on chromosome 8 that lead to increased MYC protein levels.The translocation paner for MYC is usually the IgH locus (t (8;14)) but may also be the Ig kappa (t (2;8)) or lambda (t (8;22)) light chain loci. Reference : Robbins and Cotran Pa...
Pathology
Haematology
938692b4-d85e-42ab-9cd0-3490a81f105b
Most common thyroid Cancer is -
Papillary carcinoma
Follicular carcinoma
Medullary carcinoma
Anaplastic carcinoma
0a
single
Papillary Carcinomas are the most common form of thyroid Cancer.
Pathology
null
3835d1fa-11be-492b-aaa3-f2e013062126
Reflex responsible for tachycardia during right atrial distension is
image_question
image_question
image_question
image_question
3d
single
Reflex resposible for tachycardia during right atrial distension is Bainbridge reflex. Atrial Reflex Control of hea rate: The Bainbridge Reflex The stretch recceptors of the atria that elicit the Bainbridge reflex transmit their afferent signals through the vagus nerve nerves to the medulla of the brain. Then efferent ...
Physiology
All India exam
84740c43-e67a-4975-a519-76e317939b5b
In Wegeners glomerulonephritis characteristic feature seen is
Granuloma in the vessel wall
Focal necrotizing glomerulonephritis
Nodular glomerulosclerosis
Interstitial granuloma
1b
multi
This is a necrotising vasculitis characterised by specific triad . Granuloma of the lung and the upper respiratory tract . Vasculitis of small to medium sized vessels . Glomerulonephritis Robinns 9 th edition page no. 353
Pathology
Cardiovascular system
d7f6d349-9b61-4571-88da-2e1a5f31a2e9
Preterm baby with PDA, which is the least idly findings?
CO2 washout
Bounding pulses
Pulmonary hemorrhage
Necrotising enterocolitis
0a
single
PDA in preterm neonate In previous explanations I have explained that chances of spontaneous closure of PDA are higher in premature infants as there is no structural abnormality. However, you should keep in mind that this fact is true when we are comparing the spontaneous closure of PDA between term and pre-term neona...
Pediatrics
null
2585e290-0e06-4b09-8ea5-a42aff4e560f
MRI magnet is a
Ferromagnet
Paramagnet
Simple magnet
Superconducting-magnet
3d
single
MRI uses a Superconducting magnet which is kept cool using Helium. A superconducting MRI magnet comprises a steel cryostat with the superconducting coils immersed in liquid helium at 4.2 Kelvin (-269degC or -452degF).
Radiology
Magnetic Resonance Imaging
14c1a3d3-8a46-4293-939e-05c78465e520
A 35-yrs-old woman complains of attacks of breathlessness, cyanosis and flushing. Apart from occasional diarrhea she has no abdominal symptoms. Abdominal examination reveals an enlarged nodular liver. If laparotomy is done, we could expect to find:
An ovarian tumor
A multicentric hepatoma
An appendicular carcinoid
Crohn's disease
2c
single
History of breathlessness, cyanosis and flushing points towards carcinoid syndrome. Enlarged nodular liver means hepatic metastasis, which is essential to produce carcinoid syndrome. Appendicular carcinoids are detected in I in ever) 200-300 appendicectomies. It is one of the commonest sites for carcinoid tumours. Carc...
Unknown
null
b264a4c3-98a8-4a67-9801-997e385aa3b1
A common source of Staphylococcus in the hospital is
IV fluids
Infected wounds
Hands of hospital personnel
Bed linen
1b
single
Staphylococci are the primary parasites of human beings and animals, colonizing the skin, skin glands and mucous membranes. The most common source of infection in human patients and carriers, animals and inanimate objects being less important. Patients with superficial infections and respiratory infection disseminate l...
Microbiology
null
f370fce9-a1b8-4b65-ac6b-34037c278f6e
The most common mechanism of drug resistance in staphylococci is
Conjugation
Plasmids
Transduction
Translation
2c
single
The most common mechanism of drug resistance in staphylococci is through production of beta lactamase or penicillinase, which inactivates penicillin by splitting the beta lactum ring. These are inducible enzymes which are plamid mediated. They can be transmitted by transduction or conjugation. Ref: Textbook of Microbio...
Microbiology
Bacteriology
5aed19c4-2720-464b-905a-6563b42357c2
Which bone pathology does patients with Maffucci syndrome and olliers disease present with?
Osteochondroma
Enchondromas
Ewings sarcoma
Osteosarcoma
1b
single
Both cases present with multiple enchondromas
Pathology
null
7ea19b7c-09c1-478c-99a0-536589e289d7
Two groups are tested for anemia. Which test should be used ?
Paired T-test
Unpair T-test
Chi-square test
ANOVA
2c
single
Ans. is `c' i.e., Chi-square test Observations in the given question are in the form of qualitative data (anemia present or not). Thus Chi-square test should be used. Chi square test Is used when the observation are in the form of propoions (for qualitative data) The outcome are in clear cut answers; yes or no. As in t...
Social & Preventive Medicine
null
855156f3-afd1-46f8-b714-9d229748229e
All are true about colon-rectal cancers except
Tumours of the left side of the colon usually present with a change in bowel habit
Tumours of the right side of the colon present with iron deficiency anaemia
Right present earlier then left sided cancers
Left sided cancers are more common than right
2c
multi
Tumours of the left side of the colon usually present with a change in bowel habit or rectal bleeding, while proximal lesions typically present later, with iron deficiency anaemia or a mass.Iron deficiency anaemia in any man or non-menstruating woman should lead to a search for a source of bleeding from the GI tract.Em...
Surgery
G.I.T
6b883a02-f033-4da5-ae04-e826a890f56d
Tooth whitening strip is:
H2O2
HF
Carbamide peroxide
Sodium perborate
0a
single
Hydrogen peroxide used in dentistry as a whitening agent ranges in concentration between 5 and 35%. Ref :Grossman’s endodontics,13th edition, pg no:504
Dental
null
17304376-6d26-4e05-b9a1-900636d60da7
In an ideal restoration, gingival margin should be:
Below contact point but 1mm occlusal to gingival crest
Below contact point but at level of gingival crest
Below gingival crest
At contact point
0a
single
null
Dental
null
7b804ab3-5eea-44fd-a256-d575b37a82fb
A 65-year-old man with H/O 30 pack years of smoking presents with weight loss, cough with expectoration and hemoptysis for 40 days. Serum Na was found to be 124 mEq/L. Serum Ca -10 mg/dl. Chest X ray showed a hilar mass. Brush cytology and sputum was positive for tumor cells. What of the following subtypes of lung carc...
Squamous cell carcinoma
Adenocarcinoma
Small cell carcinoma
Large cell carcinoma
2c
multi
Hilar mass suggests either squamous cell or small cell carcinoma. Hyponatremia due to SIADH is more likely in ors of Small cell. Hypercalcemia and cavitation are more likely in ors of squamous cell carcinoma
Unknown
Integrated QBank
650bd3ce-790c-4576-98b6-4f827f1f7f9e
Arneth count is counting of:
Lymphocytes
Lobes in neutrophils
Granules in eosinophils
WBC in bone marrow
1b
single
Counting the number of neutrophils with different nuclear lobes and expressing the count as percentage of cells with different number of nuclear lobes is called Arneth count. Clinical significance: The Arneth count is useful in judging the rate of formation of neutrophils. Individuals who have a larger percentage of ne...
Physiology
null
630a2a81-123c-4f7a-8a64-f6a0cdbfb6a5
Palindromic DNA implies-
Sho stretches of DNA
Recognised by specific restriction endonuclease
Codes for bacterial resistance
All
3d
multi
Ans. is 'a' i.e., Sho stretches of DNA; 'b' i.e., Recognised by specific restriction endonuclease; c i.e., Complementary strands Palindromic DNA o A DNA sequence consists of two complementry strand coiled in a double helicle structure. o A sequence of duplex DNA that is same when two strands are read in opposite direct...
Pathology
null
5d8f36d4-9525-445f-a130-714a1c2f0c01
"Citron bodies" and boat or leaf-shaped pleomorphic organism in an exudate is
Clostridium welchii
Clostridium edematiens
Clostridium septicum
Clostridium tetani
2c
single
Clostridium septicum: citron bodies, boat or leaf-shaped polymorphic bacilli. Motile by peritrichous flagella. Saccharolytic and produce abundant gas. Produce alpha, beta, delta and gamma toxin. Gas gangrene, Braxy or malignant edema is caused. Reference: Textbook of Microbiology; Anathanarayan and paniker's; 10th edit...
Microbiology
Bacteriology
dd0ba8de-7c14-4b87-9e7a-75ca0bc5aa8e
During the early stages of the inflammatory response, histamine induced increased vascular permeability is most likely to occur in:
Arteries
Precapillary arterioles
Capillaries
Postcapillary venules
3d
single
Acute inflammation causes fluid and cells to leak out of blood vessels into the interstitial tissue because of increased permeability of postcapillary venules.
Pathology
null
b2e59d29-1b06-4566-9de9-25e5624c2aa8
In retinal detachment –
Effusion of fluid into the suprachoroidal space
Retinoschisis
Separation of sensory retina from pigment epithelium
None of the above
2c
multi
In retinal detachment the fluid accumulate in subretinal space i.e., the space between neurosensory epithelium (sensory epithelium or neuroepithelium) and pigmented epithelium. Retinoschisis Vs Retinal detachment It has already been explained that in retinal detachment there is separation between neurosensory layer a...
Ophthalmology
null
7bbe17f4-b225-4073-b261-66c031c92225
Specificity of a screening test is the ability of a test to detect
True positives
False positives
False negatives
True negatives
3d
multi
Specificity is defined as the ability of a test to identify correctly those who do not have the disease, that is &;true-negatives&;Sensitivity is defined as the ability of a test to identify correctly all those who have the disease, that is &;true-positive&;
Social & Preventive Medicine
Screening
0830b6b6-fa27-4936-ac03-ca44b3997c31
You see the newborn baby shown below for the first time in the nursery. You consult plastic and reconstructive surgery as well as the hospital's speech therapist. Understandably, the parents have many questions. Which of the following statements is appropriate anticipatory guidance for this family?
Parenteral alimentation is recommended to prevent aspiration.
Surgical closure of the palatal defect should be done before 3 months of age.
Good anatomic closure will preclude the development of speech defects.
Recurrent otitis media and hearing loss are likely complications.
3d
multi
(d) Source: (Hay et al, pp 1047-1048. Kliegman et al, pp 1252-1253. McMillan et al, pp 469-472, 2661-2662. Rudolph et al, pp 705- 710.) The infant pictured has bilateral cleft lip and palate. The incidence in the general population is about 1:1000 live births, but occurs in about 4% of the siblings of affected infants....
Pediatrics
New Born Infants
41b95dcb-b0e4-4eaa-a808-847ecf376ddf
Last organ to be dissected during autopsy in asphyxial death is
Neck
Head
Abdomen
Thorax
0a
single
Ans. is 'a' i.e. Neck Detailed study of the neck organs is required during autopsy of asphyxia death.Cranial thoracic and abdominal organs are removed before dissecting the neck, so that, the body is drained of blood.Such draining provides a clean bloodless field for the study of neck organs and prevents any artifactua...
Forensic Medicine
Injuries
ff811171-e9f5-4425-9e00-25fc9a12cd3a
Treatment of choice for sputum positive pulmonary tuberculosis detected in Ist trimester of pregnancy:
Defer till second trimester
Sta cat. I immediately
Sta cat. II immediately
Sta cat. III immediately
1b
single
Sta cat. I immediately Repeat May 10
Social & Preventive Medicine
null
1a06e92e-3f10-41cf-a9bb-4a4127439247
All are features of Acute Renal Failure (ARF) except -
Hypotension
Metabolic acidosis
Hyperkalemia
Hypertension
3d
multi
null
Medicine
null
40c37503-baa0-4e32-b4ec-6a8cd9eb0d37
Skirrow's medium is used for?
Clostridium tetani
Corynebacterium diphtheria
Campylobacter jejuni
Helicobactor pylori
2c
single
Ans. is 'c' i.e., Campylobacter jejuni . Media used for cultivation of H. Pylori are : i) Skirrow's medium Butzler's medium iii) Compy BAP medium
Microbiology
null
259cd51e-45f9-4df9-8675-a55a0fffd25c
Glycerol is an-
Osmotic diuretic
Purgative
Antidiabetic
Antiemetic
0a
single
Ans. is 'a' i.e., Osmotic diuretic o Glycerol is an orally active osmotic diuretic which may be used to reduce intraocular or intracranial tension. Intravenous glycerol can cause hemolysis.
Pharmacology
null
d0ff45ed-3b92-45c9-ac7e-e60a0d756c5f
ANCA is associated with
Henoch-Schonlein Purpura
Wegener’s granulomatosis
Rheumatoid arthritis
Goodpasture syndrome
1b
single
• ANCA or antineutrophilic cytoplasmic antibodies are formed against certain proteins in the cytoplasm of neutrophils. Out of the given options, Wegener’s granulomatosis is most strongly associated with ANCA.
Pathology
null
ce9dcf69-1dd8-48e9-9f8a-d074e7d111df
Pleural effusion in rheumatoid ahritis is typically associated with the following features except
Glucose > 60 mg/dl
Protein > 3 gm/di
Pleural fluid protien to serum protein ratio of >0 .5
Pleural fluid LDH to serum LDH ratio of >0.6
0a
multi
Ans. is 'a' i.e., Glucose > 60 mg/dl Causes of low glucose pleural fluid Malignancy Rheumatoid ahritis Empyema Hemothorax Paragonimiasis Churg strauss syndrome Lupus pleuritis (occasionally)
Medicine
null
f7de6b71-c800-45bb-b434-1911f91cd74d
National Population Policy was first formed in 1976. Goals of National Population Policy are the following, EXCEPT:
Decrease IMR to below 30 per 1000 live bihs
Reduce MMR to below 100 per 100,000 live bihs
Achieve 100 per cent registration of bihs, deaths, marriage and pregnancy
Bring down TFR to replacement level by 2015
3d
multi
The objective of National Population Policy (NPP) 2000 is to bring the total feility rate (TFR) to replacement level by 2010. All the other options are the goals to be achieved by NPP. Ref: Park's Textbook of Preventive and Social medicine, 19th edition, Page 391.
Social & Preventive Medicine
null
6c5b0f47-f468-4306-aac9-7ec8ff48ccf0
Prothrombin Time (PT) detects deficiency of all the following clotting factors EXCEPT
II
V
VII
VIII
3d
multi
The time required for clotting to occur is called the prothrombin time (PT). Normal PT = 15-20 seconds. Prolonged PT suggests the possibility of deficiency of factors II (prothrombin), V, VII and X. Prothrombin level is low in vitamin K deficiency and various liver and biliary diseases.
Physiology
Blood Physiology
264f052e-833e-4856-87c2-1a6ff1b2348b
Neuropsychiatric complications of HIV include all except
Dementia
Depression
Mania
OCD
3d
multi
Please read on HIV and its neuropsychiatric manifestations
Anatomy
All India exam
636e832d-7c15-4ac5-bb1a-df1ff76b61dc
A child comes with steroid resistant nephrotic syndrome secondary to FSGS, not responsive .to methylprednisolone. What next should be given ?
Oral cyclophosphamide
Oral cyclosporine
Oral mycophenolate
IV cyclophosphamide
1b
single
Ans is 'b' i.e., Oral cyclosporine o The treatment options for steroid resistant nephrotic syndrome are: (i) Calcineurin inhibitors (cyclosporine, Tacrolimus) (ii) IV or oral cyclophosphamide (iii) Levamisol (iv) Mycophenolate (v) Pulse coicosteroid o All above immunosuppressants are used along with coicosteriods (Pred...
Pediatrics
null
48bc634a-c1f2-43ed-8d1d-060e94cf2a24
Placing a ring liner approximately 3.25 mm short of the ends of the ring tends to
Produce a more uniform expansion and the expansion will not be in a vertical direction hence no distortion
Produce a more uniform contraction
Produce no change
Produce distortion
0a
single
null
Dental
null
34601410-63af-4fd3-8dfd-9060caa153ae
Resistance to drugs in tuberculosis develops by: March 2011, March 2013
Transduction
Conjugation
Transformation
Mutation
3d
single
Ans. D: Mutation MDR-TB strains could arise as a consequence of sequential accumulation of mutations conferring resistance to single agents, or by a single step process such as acquisition of an MDR element. Resistance to common anti-TB drugs The most common mechanism of INH resistance is by mutation of the catalas-per...
Pharmacology
null
f05df579-eddf-4f47-8245-d20ebd11474c
Guttman sign is seen in
Branchial plexus block
Supra clavicular block
Stellate ganglion block
None
2c
multi
Guttman sign is ipsilateral nasal stuffiness seen in stellate ganglion block.
Anaesthesia
null
2b520b20-42d1-4101-8674-168f78114b2a
Mean Hb values are compared in two population groups. The best test is -
Paired T test
Unpaired T test
Chi-square test
Fisher'stest
1b
single
Ans. is 'b' i.e., Unpaired T test Student t-testo Small samples do not follow normal distribution as large ones do. To overcome this problem T test was devised by W.S. Cassette whose pen name was 'student' and hence this test was called student't' test.Application of test :o It is applied to find the significance of di...
Social & Preventive Medicine
Statistical Tests
42b57ece-1513-46d6-8d84-689b1c73061b
All are components of Behaviour sciences except-
Political Science
Anthropology
Sociology
Psychology
0a
multi
Ans. is 'a' i.e., Political Science
Social & Preventive Medicine
null
0c4e475c-941a-4725-adea-66fb04ea79f9
an anxiuous mother brought her 4yr old daughter to the pediatrician .the girl was passing loose stools past 20days .this was often associated with pain abdomen .stool examination showed the following organism :
entamoeba hystolytica
giardia lambia
cryptosporidium parvum
e.coli
1b
single
Pathogenesis G. lamblia inhabits in the duodenum and upper ileum Trophozoites are attached to the mucosa surface by sucker, reproduced by binary fission Histology shoening of microvilli, elongation of crypts, and damaging the brush border of the absorptive cells Mechanical blockage of the intestinal mucosa, competition...
Microbiology
All India exam
4ac3bbc1-583b-4781-94b1-640a2021d8f1
Which of the following is not a landmark for facial nerve during parotid surgery?
Anterior belly of digastric muscle
Styloid process
Tragal pointer
Squamotympanic fissure
0a
single
The main methods of facial nerve trunk localisation can be divided into antegrade and retrograde. The former utilises anatomical landmarks to identify the nerve trunk after its exit from the stylomastoid foramen, which is then traced distally.Landmarks commonly used are:The inferior poion of the cailaginous canal. This...
Surgery
Head and neck
bbc0db27-6032-42e9-9387-a2cc84229b56
Inclusion bodies are found in all except:
Herpes
EBV
Poliovirus
CMV
1b
multi
Inclusion bodies are nuclear or cytoplasmic aggregates of stainable substances, usually proteins. They typically represent sites of viral multiplication in a bacterium or a eukaryotic cell and usually consist of viral capsid proteins. It is the most characteristic histological feature in virus-infected cells. It is of ...
Pathology
null
cdf92205-97c4-4524-bda9-225a7377bfd0
All are associated with Wernicke, encephalopathy, EXCEPT:
Cog-wheel rigidity
Alteration in mental function
Vlth nerve palsy
Ataxia
0a
multi
Ans. is 'a' Cogwheel rigidity
Medicine
Nutrition
952e4ac2-8337-4692-b5f8-d07f24cc1673
For pancreatic injury true is -
Most are iatrogenic
Blunt trauma most common
Urine amylase is diagnostic
HRCT is investigation of choice
3d
multi
Ans. is 'd' i.e., HRCT is investigation of choice o Pancreas being a retroperitoneal structure, peritoneal lavage is not helpful in making the diagnosis of pancreatic injury.o CT scan is the best diagnostic procedure, apart from an exploratory' laprotomy.More about Pancreatic injuryo About two-thirds are due to penetra...
Surgery
Trauma (Pancreas)
ef6c3a44-67c2-4815-ac75-306af543e853
Niacin deficiency causes
Pigmentation
Diarrhea
Rash
Lactic acidosis
1b
single
Deficiency of niacin: A deficiency of niacin causes pellagra, a disease involving the skin, gastrointestinal tract, and CNS. The symptoms of pellagra progress through the three Ds: dermatitis, diarrhoea, dementia--and, if untreated, death. Reference: Lippincott Textbook of Biochemistry pg no. 380
Biochemistry
vitamins
9e28ff9e-c036-42ce-8fd3-356b8f162456
Which of the following is not used to treat ADHD?
Dexamphetamine
Dexmethylphenidate
Dextromethorphan
Clonidine
2c
single
Dextromethorphan is a NMDA antagonist used as cough suppressant.
Psychiatry
null
cb4a8cd0-b22a-483f-ab16-f837234c1816
Ocular symptom of Von Recklinghausen disease is
Deformed anterior chamber with reduced angle of AC
Glaucoma
Choroidal hemangioma
Subretinal neovascularization
1b
single
• NF-1 is the most common phakomatosis, affecting 1:4000 individuals, and presents in childhood. • The gene locus is on 17q11.
Unknown
null
68fe6e9e-38ad-4226-bbcb-b62eafa75786
Mallampati score is done for assessing:
Size of the airway
Oral cavity of patient for intubation
Mobility of neck
Size of ET tube
1b
multi
Ans. (b) Oral cavity of patient for intubation* Mallampati score, also known as Mallampati classification is used to assess the oral cavity of patient to predict the ease of intubation.* It is assessed by looking at the anatomy of the oral cavity; specifically, it is based on the visibility of the base of soft palate, ...
ENT
Oral Cavity
bcaa93f7-4f8b-44c3-b8ac-616fd9e48420
radiation exposure occurs in all except ?
ct scan
mri
fluroscopy
plain xray
2c
multi
fluoroscopy uses sonographic waves which is a sound wave and doesnt have radiation effect. Fluoroscopy is also an imaging tool. Allows physicians to look at various body systems. Shows movement of body pas. Also shows instruments or dye a continuing stream of x-ray images. Approximately 25-30 images per second Used in ...
Radiology
All India exam
0f2639ce-a653-42f3-9d2e-dbfbb3c37795
Teratoma is best describad as:
Hamartous developmental manifestation consisting of three different layers
Occurs most commonly in stomach and lungs
Originates from mesodermal tissue
Associated with very painful condition
0a
single
null
Pathology
null
fd25bd4a-7636-49b6-a352-1b90c08254b9
Hypeension is not seen with :
SNRIs
amphetamine
Erythropoietin
L-dopa
3d
single
Levodopa: ADVERSE EFFECTS- Most are dose-related, but are usually reversible. 1. Nausea and vomiting It occurs in almost every patient. Tolerance gradually develops and then the dose can be progressively increased. 2. Postural hypotension It occurs in about 1 I 3 of patients, but is mostly asymptomatic; some patients e...
Pharmacology
Other topics and Adverse effects
ec8002d7-296b-49ba-8fc3-7bcac4616b97
Spider leg appearance in Intra venous urography is seen in-
Congenital Polycystic Kidney Disease
Hydronephrosis
Renal stone
Renal cell carcinoma
0a
single
Ans. is 'a' i.e., Congenital polycystic kidney diseaseRadiological appearanceo Paint - brush appearanceo Soap - bubble nephrogramo "Swiss - cheese" nephrogramo Dense persistent nephrogramo Striated nephrogramMedullary sponge kidneyHydronephrosisAdult polycystic kidney diseaseAcute ureteric obstruction, hypotensionInfan...
Radiology
Urogenital System
d50a55b2-5b03-4667-b989-6cebcb58eb30
A community has a population of 10,000 and a birth rate of 36 per 1000. 5 maternal deaths were reported in the current year the MMR is –
14.5
13.8
20
5
1b
single
You should keep in mind that MMR denotes maternal mortality ratio (not maternal mortality rate).
Social & Preventive Medicine
null
cf01f7a0-989f-407c-b66b-404dd0496a4f
TRUE statement about aspirin is:
In an afebrile patient acute overdose of aspirin produces hypothermia
Aspirin suppresses flushing associated with large dose of nicotinic acid
Aspirin therapy prevents granulomatous lesions and cardiac complications of acute rheumatic fever
Long term aspirin therapy increases the risk of developing colon cancer
1b
multi
Nicotinic acid can cause flushing due to release of PGs. Premedication with aspirin decreases this complication. Aspirin can cause hypehermia in overdose. It decreases the risk of developing colon cancer.
Pharmacology
NSAIDs, Gout and Rheumatoid Ahritis
aae9c1cb-2a87-4610-89e1-ff3fbc6bb5d9
All of the following are the causes of relative polycythemia except:
Dehydration.
Dengue haemorrhagic fever
Gaisbock syndrome
High altitude.
3d
multi
Answer is D (High altitude) High altitude is associated with physiological increase in erythropoetin levels and leads to absolute polycythemia and not relative polycythemia. Relative erythrocytosis due to reduction in plasma volume alone is also known as stress or spurious erythrocytosis or `Geisbock's syndrome'
Medicine
null
c0f44b56-c2ec-49ca-87b4-59fd52fd29c6
Investigation of choice in detecting small para-aoic lymph node is -
Ultra sound scan
CT scan
Lymphangiography
Aeriography
1b
multi
Ans. is 'b' i.e., CT scan
Surgery
null
4acff987-9eb6-4135-abe2-a8105caf440c
Which organ is NOT affected by Plasmodium falciparum?
Hea
Liver
Lungs
Kidney
1b
single
The trophozoites of Plasmodium falciparum disappears from peripheral circulation after about 24 hrs. By then a strain specific high molecular weight antigen appears on the surface of infected red cells, associated with knob like projections on the erythrocyte membrane. Such red cells disappear from peripheral circulati...
Microbiology
null
0b6e3ebb-5820-4976-9c98-0885729065dd
A child suffering from acute diarrhoea is brought to the casualty and is diagnosed as having severe dehydration with pH of 7.23. Serum Na-125, Serum K-3, HCO3 16. The best I.V. fluid of choice is -
3% Saline
N/3 Saline + 10% dextrose
Normal saline
N/3 saline + 5% dextrose
2c
single
null
Medicine
null
e9912230-2e87-4de7-9eab-ab99007069bc
Both HBsAg and HBeAg are positive in
Acute infectious Hepatitis B
Chronic Hepatitis B
Recovery phase of Hepatitis B
Individuals vaccinated with Hepatitis B
0a
multi
Ref: Park&;s Textbook of Preventive and Social Medicine 25 th Ed Pgno : 235 SEROLOGICAL PATTERNS IN HEPATITIS B HBsAg Anti-HBs Anti-HBc HBeAg Anti-HBe Interpretation + - IgM + - Acute Hepatitis B + - IgG + - Chronic Hepatitis B+ replication - + IgG - + Recovery from Hepatitis B - + - - - Vaccinated individuals
Social & Preventive Medicine
Communicable diseases
aa5c726a-6c64-4a2a-bc27-a05abd610ea7
Hypercalcemia caused by -
Thyrotoxicosis
VnDiotoneation
Saroidosis
Furosemide
0a
single
hypercalcemia can be a manifestation of a serious illness.Although hyper parathyroidism , a frequent cause of asymptomatic hypercalcemia, is a chronic disorder in which manifestations may be expressed only after months or years.The cause of hypercalcemia is numerous,but hyper parathyroidism. Hypercalcemia from any caus...
Medicine
Endocrinology
10701b01-e05e-45ae-9aae-2869013b0944
Esthiomine is seen in
Chancroid
Granuloma inguinale
LGV
Syphilis
2c
single
Esthiomene is seen in LGV which refers to hyperophic enlargement with ulceration of the external genitalia LGV is caused by L1 L2 L3 strain of chlamydia trachomatous L2 is most common Esthiomene is a medical term referring to elephantiasis of the female genitals. In the past the term has also referred to elephantiasis ...
Dental
All India exam
86ef489e-a1ce-469a-9fc0-7027607d70a8
A 6-year-old drowsy child came in emergency with history of vomiting, loose motion for 3 days. On examination he had sunken eyes, hypothermia, skin on pinching was taking 5 seconds to reve. What is your diagnosis?
No dehydration
Mild dehydration
Some dehydration
Severe dehydration
3d
single
In this case, sunken eyes and skin "goes back very slowly" (in 5 seconds) in a "lethargic" (drowsy) child, so it is a case of severe dehydration.
Pediatrics
Disorders of Gastrointestinal System Including Diarrhea
32a77016-8b23-49fb-81e1-fd9864ffb57c
Which of the following statements about contrast in radiography is true:
Ionic monomers have three iodine atoms per two paicles in solution
Osmolar contrast agents may be ionic or non ionic
Gadolinum may cross the blood brain barrier
lohexol is a high osmolar contrast media
0a
multi
A i.e. Ionic monomers have three iodine atoms per two paicles in solution Ionic contrast agents dissociate (ionize) in water in 2 ioins (or osmotic paicles) per molecule whereas nonionic agents do not ionize or dissociate. All monomers contain I benzene ring with 3 iodine atoms and dimers contains 2 benzene rings with ...
Radiology
null
ee6d377f-1372-4b56-8165-48b35bbe0888
The most common type of cerebral palsy is?
Spastic
Atonic
Extrapyramidal
Mixed
0a
single
a. Spastic(Ref: Nelson's 20/e p 2896-2899; Ghai 8/e p 581-583)Most common type of cerebral palsy is spastic diplegia in 35% cases, followed by Hemiplegia in 25% casesSpastic quadriplegia is the most severe form of CP because of marked motor impairment of all extremities and the high association with intellectual disabi...
Pediatrics
Central Nervous System
1f0ec916-79c2-4596-abab-5e5eebacca93
BCR - ABL hybrid gene is present in
Burkitt's lymphoma
Retinoblastoma
Breast carcinoma
CML
3d
single
(CML) (215-HM) (315, 697-98-R) (464-Basic pathology 8,h)BCR-ABL hybrid gene - ABL gene is a non GF receptor proto-oncogene having tyrosine kinase activity. ABL gene from its normal location on chromosome 9 is translocated to chromosome 22. Where it fuses with BCR (breakpoint cluster region) gene and forms an ABL, BCR h...
Pathology
Neoplasia
55a136e5-9e46-43fb-894c-274853287a97
Pansystolic murmur at apex with soft first hea sound is the key sign of which one of the following ?
Aoic regurgitation
Mitral regurgitation
Ventricular septal defect
Atrial septal defect
1b
single
MR : The regurgitant jet causes an apical systolic murmer.Pansystolic murmer with thrill, soft S1 AR: Early diastolic murmer ASD: Systolic flow murmer over pulmonary valve, diastolic flow murmer over tricuspid valve, wide fixed splitting of S2. VSD: Pansystolic murmer usually heated best at the left eternal edge Ref: H...
Medicine
C.V.S
a4f0c4dd-3114-4a20-ae84-d95cdad10ea6
Most sensitive parameter in monitoring iodine deficiency control programme is:
Goitre
Urine T3.T4
Growth retardation
Neonatal hypothyroidism
3d
single
Ans: D (Neonatal hypothyroidism) Ref: Park's Preventive and Social Medicine, 22nd edition. Pg 579Explanation:Iodine level in salt at consumption level 15 ppm.Iodine level in salt at production level 30 ppmIodine oil injection will provide protection for 4 years.Sensitive indicator for consumption of appropriate level o...
Social & Preventive Medicine
Environment and Health
d65af515-20e7-4ba0-af71-8cf91d3a1298
Air on either side of the bowel wall on a radiograph is called:
Air under diaphragm sign
Cupola sign
Doges cap sign
Rigler sign
3d
multi
The Rigler sign, also known as the double-wall sign, is a sign of pneumoperitoneum seen on an abdominal radiograph when gas is outlining both sides of the bowel wall, i.e. gas within the bowel's lumen and gas within the peritoneal cavity. It is seen with large amounts of pneumoperitoneum (>1000 mL).
Radiology
Gastrointestinal Radiology
8d006fd4-5995-4ebf-bec6-0454d92d4abc
In intubation which drug is used instead of succinylcholine
Doxacurium
Dantrolene
Rocuronium
None
2c
multi
Muscle relaxants are used in intubation, which are of two types: Depolarizing muscle relaxant, i.e., Succinylcholine Non-depolarizing muscle relaxant, eg., Rocuronium, vecuronuim, Atracurium, etc
Anaesthesia
Anaesthetic equipments
5f1d776c-4b2c-4d03-8711-e6242a39d8f4
Which of the following is the location of human leukocyte antigen (HLA)?
Sho arm of chromosomes 3
Sho arm of chromosomes 6
Long arm of chromosomes 3
Long arm of chromosomes 6
1b
single
The human MHC (human leukocyte antigen; HLA) consists of a linked set of genes encoding major glycoproteins involved in antigen presentation. The complex locates to the sho arm of chromosome 6 and divides into three separate regions: class I, class II, and class III genes. The class I "classic" region encodes HLA-A, HL...
Pathology
null
d1a046e5-259a-4644-9191-ae59e4fa2a05
In early congenital syphilis, which is not seen –
Keratitis
Vesicular rash
Chorio retinitis
Rhinitis
0a
single
null
Pediatrics
null
789d81b0-e634-4760-b4ce-fcf6808904a2
Recurrent interosseous aery is a branch of -
Posterior interosseous aery
Anterior interosseous aery
Radial aery
None
0a
multi
Ans. is 'a' i.e., Posterior interosseous aeryInterosseous recurrent aery is a branch ofposterior interosseous aery.
Anatomy
null
b6b181dd-c318-4545-a1cd-ec43f81ccbd3
As per WHO low birth weight is defined as
Gestational age < 34 weeks
Birth weight < 10th percentile
Birth weight less than 2.5 kg
Gestational age < 28 weeks
2c
single
null
Social & Preventive Medicine
null
8ee40672-2334-4469-be7c-d2a3d1516621
Drug used in heparin overdose -
Protamine sulfate
Phylloquinone
Ticlopidine
Clopidogrel
0a
multi
Ans. is 'a' i.e., Protamine sulfate The most common adverse effect of heparin is bleeding.Protamine sulfate is an antidote of heparin. Protamine is strongly basic low molecular weight protein.Protamine sulfate is rarely needed in heparin induced bleeding because the action of heparin disappears by itself in few hours.T...
Pharmacology
Anticoagulants and Coagulants