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c94ca54d-715d-4979-b6d5-4e514138a2d9 | The risk of neonatal chicken pox is the maximum, if maternal infection occurs - | During the first trimester | During the second trimester | Within five days of delivery | Within six weeks of delivery | 2c | single | Ans. is 'c' i.e., Within 5 days of delivery o Risk of neonatal chicken pox is maximum if maternal infection occurs near delivery ( 5 days before delivery or 48 hours after). | Pediatrics | null |
c2dc8298-58fb-412f-b62f-faa2a3969416 | Hypersensitivity angiitis is seen in - | SLE | Polyarteritis nodosa | Henoch schonlein purpura | Buerger's disease | 2c | single | HSP is not hypersensitivity angiitis. But the best answer amongst the given options is HSP because it is the most important differential of hypersensitivity angiitis.
Hypersensitivity angiitis
Hypersensitivity vasculitis or hypersensitivity angiitis or leukocytoclastic angiitis is a small vessel vasculitis due to hy... | Pathology | null |
dc53f1ae-b218-4953-a8bf-9dec4d488687 | Cocaine withdrawal causes all except ? | Dysphoria | Fatigue | Disturbed sleep | Creeping bugs | 3d | multi | Ans. is 'd' i.e., Creeping bugs Patients withdrawing from cocaine typically experience fatigue, dysphoria, diurbed sleep, and some craving; some may experience depression".___________ Kaplan & Saddock. o Creeping bugs are seen in chronic cocaine abuse (not due to withdrawal). Cocaine Cocaine is an alkaloid derived from... | Forensic Medicine | null |
4397cfb9-db93-4106-91b4-b966e1ec140a | About 90 days post-bone marrow transplant, a 55-year-old white woman began to complain of dry cough, shortness of breath, and chest pain. She was started on antibiotics and blood culture obtained at the time was negative and there was not improvement. A computed tomography (CT) scan of the lungs showed a halo of low at... | Aspergillosis | Candidiasis | Histoplasmosis | Mucormycosis | 0a | single | Aspergillus is widespread in nature and produces small conidia that are easily aerosolized. Atopic individuals often develop severe allergic reactions to the conidial antigens. In immunocompromised patients, the conidia may germinate to produce hyphae that invade the lungs and other tissues. Progress of disease can be ... | Microbiology | Mycology |
9cdd324d-7f44-441d-9b4e-1c5c765afe79 | True about vagina development is all except | Mucous membrane of vagina is derived from endoderm of urogenital sinus. | Hymen is remnant of sinovaginal bulb. | Upper 1/3 rd of vagina is derived from mullerian ducts. | Lower 1/3rd of vagina is derived from urogenital sinus. | 2c | multi | Mullerian duct forms upper 2/3rd of vagina. | Gynaecology & Obstetrics | null |
351a091a-f076-4e56-a419-d3a2b35c9441 | Minimum hCG level that a urine pregnancy test can detect is? | 5 m IU/ ml | 10-20 m IU/ ml | 20-30 rn IU/ ml | 35 m IU/ ml | 0a | single | 5 m IU/ ml REF: Danfoh's Obstetrics and Gynecology, 10th Edition page 4, Current OB/GYN > Chapter 9. Normal Pregnancy & Prenatal Care > Normal Pregnancy > URINE PREGNANCY TEST: Sensitive, early pregnancy test measure changes in levels of hCG. There is less cross-reaction with luteinizing hormone (LH), follicle stimulat... | Gynaecology & Obstetrics | null |
48817fc0-2e83-4081-a75e-564fdc51452e | In competitive inhibition the relation Km and Vmax is one of the following - | Km and Vmax are the same | Km increases and Vmax is the same | Km decreases and Vmax increases | Km and Vmax decreases | 1b | single | Ans. is 'b' i.e., Km increase and Vmax is the same Competitive inhibition-Km is high Vmax is sameNon Competitive inhibition-Vmax lowered Km unaltered Type of inhibitorKmVmaxReversible inhibbitor o CompetitiveIncreasedNo effecto Non-competitiveNo effectDecreasedo UncompititiveDecreasedDecreasedIrrversible inhibitor (sam... | Biochemistry | Enzyme Kinetics |
f49e3678-dfb9-4708-962a-98bc19f858b6 | Organ of rosenmullar is remnant of | Endodermal sinus | Mulleria duct | Mesonerphric tuble | Paramesonephric duct | 2c | single | The epoophoron or epoophoron (also called organ of Rosenmuller or the parovarium) is a remnant of the mesonephric tubules that can be found next to the ovary and fallopian tube | Anatomy | General anatomy |
f00ca20e-b223-4fa2-a65b-a72d76750e12 | Which of the following organism can penetrate the normal cornea –a) Gonococcusb) Pseudomonasc) Diphtheriad) Streptococcuse) Staphylococcus epidermidis | a | bc | ad | ac | 3d | single | The organisms which can penetrate intact corneal epithelium are Neisseria gonorrhoea, Haemophilus Aegyptus, Corynebacterium diphtheriae, Listeria species and Neisseria meningitides. | Ophthalmology | null |
3032b2ed-0371-466c-8e38-ca641ff56a83 | A major source of Von Willebrand factor (vWF) – | Erythrocytes | Neutrophils | Endothelial cells | Monocytes | 2c | single | Circulating factor VIII has two components.
a) Factor VIIIc (Procoagulant protein)
This is the smaller component
It is synthesized in the liver (main source) and kidney.
It is an intrinsic pathway component required for activation of factor X.
b) Von Willebrand factor (vWF)
This is the larger component.
It is p... | Pediatrics | null |
2b479488-c917-4eab-844b-1fa7d104f9c8 | Aniseikonia refers to | Difference in the refractive power | Difference in the corneal diameter | Difference in image colour | Difference in the retinal image size | 3d | single | ANISEIKONIA Aniseikonia is defined as a condition wherein the images projected to the visual coex from the two retinae are abnormally unequal in size and/or shape. Etiological types: 1. Optical aniseikonia: may occur due to either inherent or acquired anisometropia of high degree. 2. Retinal aniseikonia: may develop du... | Ophthalmology | Optics and refraction |
e10e0352-c7a0-461c-b1c4-c5272f4c9a1b | Hyperextension at the metacarpophalangeal joints and flexion at the interphalangeal joints is caused by injury in the | Ulnar nerve | Radial nerve | Median nerve | Musculocutaneous nerve | 0a | single | i.e. (Ulnar nerve): (59, 134-BDC-l 5th)An ulnar nerve lesion at the writ produces ulnar claw hand'CLAW HAND - due to the un opposed action of the long flexors and extension of the fingers, there is hyperextension at the metacarpo phalangeal joint and flexion at the interphalangeal joints involving the ring and little f... | Anatomy | Upper Extremity |
82d04951-7d52-4b32-bfe3-efe3451a6cae | Which of the following grows in cell culture media | Chlamydia | Ureoplasma urealyticum | Pseudomonas aeruginosa | Trophyrema whippeli | 0a | single | Chlamydia - cell lines that have been irradiated with a metabolic inhibitor are used for isolation of chlamydia. McCoy cell treated with cycloheximide are the most commonly used cell lines. Ref: Baveja textbook of microbiology; 4th edition | Microbiology | Bacteriology |
5ffd0d7a-6821-423e-9388-a5df8f259814 | Acute appendicitis is characterized by all of the following except: September 2005 | Anorexia | Rovsing's sign | Fever >42 degree celsius | Peri-umbilical colic | 2c | multi | Ans. C: Fever >42 degree celsiusAppendicitis is more common in men The risk of perforation is:Less than 10 years old = 50%10-50 years old = 10%Over 50 years old = 30%Clinical features of appendicitis:Central abdominal pain moving to right iliac fossaNausea, vomiting, anorexiaLow-grade pyrexia (37.2-37.7 degree celsius)... | Surgery | null |
9d75784b-dd22-4e11-b427-6485cf0a93e4 | Which intrinsic muscle is not supplied by median nerve - | Abductor potlicis brevis | Opponens pollicis | First lumbrical | Adductor poll ids brevis | 3d | single | null | Anatomy | null |
f693efda-9064-4f0e-ab83-deb5c7609527 | Glucagon is secreted by | a cell | ss cell | d cell | G cell | 0a | single | Glucagon, a peptide hormone secreted by the pancreas, raises blood glucose levels. Its effect is opposite that of insulin, which lowers blood glucose levels. The pancreas releases glucagon when blood sugar (glucose) levels fall too low. Glucagon causes the liver to conve stored glycogen into glucose, which is released ... | Physiology | Endocrinology |
a8c8fb2c-2f66-457d-9517-319108efc3f2 | All of the following take part in the pathogenesis of macularedema in diabetic retinopathy except | Retinal pigment epithelium dysfunction | Oxidative stress | VEGF | Increased protein kinase - C | 0a | multi | Ans. (a) Retinal pigment epithelium dysfunctionRef: Harrision 17/e, p. 2286-2287; Yanoff and Duker 2/e, p. 877- 880; Parson's 20/e, p. 294 - 298Pathogenesis of macular edema is due to the same changes as overall for DR. | Ophthalmology | Retina |
a7582061-86ae-407e-a034-dc6035b173f0 | The following structure represents all the 3 components of the embryonic disc | Tympanic membrane | Retina | Meninges | None of the above | 0a | multi | The outer epithelial layer formed by the ectoderm, inner mucosal layer by the endoderm and middle fibrous layer by the mesoderm. Ref: Dhingra 6th edition page no.12 | ENT | Ear |
c9f2b822-b7aa-460f-8d31-c8e6d1c6f883 | If two buds of pancreas do not fuse, the anomaly is- | Ectopic pancreas | Pancreatic divisum | Annular pancreas | Accessory pancreas | 1b | single | null | Anatomy | null |
eb049c11-3639-4f48-9802-ab3ab0cb0a10 | The cardiac jelly formed around the hea tube during early development, contributes to the formation of: | Pericardium | Mesocardium | Myocardium | Endocardial cushion valves | 3d | single | Prior to looping, the acellular space between the myocardium and endocardium in the hea is filled with a deformable extracellular matrix, the cardiac jelly, secreted by the myocardium. Radioactive labeling demonstrates that proteins produced in the myocardium flow toward the endocardium and are incorporated into the ba... | Anatomy | null |
88c0403c-c2c9-481f-a56b-0c7494a43b97 | Most common presentation of organ damage in Diabetes mellitus is | Retinal changes | Microalbuminuria | Autonomic neuropathy | Coronary artery disease | 0a | single | (A) Retinal changes # CHRONIC SYMPTOMS OF DIABETES are due to vascular damage from persistent hyperglycemia.> Vascular damage leads to end-organ damage.> Other conditions associated with diabetes, such as hypertension, dyslipidemia (as well as smoking) accelerate the development of vascular damage and the chronic compl... | Medicine | Miscellaneous |
22831d6b-5bfa-481c-b67f-6cf46fc324be | A 52-year-old woman loses her right kidney following an automobile accident. A CT scan of the abdomen 2 years later shows marked enlargement of the left kidney. The renal enlargement is an example of which of the following adaptations? | Atrophy | Dysplasia | Hyperplasia | Hyperophy | 3d | single | Hyperophy Response to trophic signals or increased functional demand and is commonly a normal process. The molecular basis of hyperophy reflects the increased expression of growth-promoting genes (proto-oncogenes) such as myc and ras. -Hyperplasia (choice C) of renal tubular cells may occur, but an enlargement of the k... | Pathology | Basic Concepts |
5dc6b516-2384-4b24-8b9e-09ccaaf45084 | "adder head" appearance on excretory urography is seen in | Hydronephrosis | Infantile polycystic kidney | Ureterocele | Horseshoe kidney | 2c | single | (Ureterocele) (1310-LB) (1290-B & L 25th)Ureterocele is a cystic enlargement of the intramural portion of the ureter thought to result from congenital atresia of the ureteric orifice.* The "adder-head' on excretory urography is typical* Usually the cyst wall is composed of urothelium only and the diagnosis is confirmed... | Surgery | Kidney & Ureturs |
40a17176-8526-414b-8f1e-cc9524d5934a | Cardiac hyperaemia/vasodilation is due to which mediator? | Ach | Adrenaline | Dopamine | Adenosine | 3d | single | Histamine and adenosine are vasodilators seen in cardiac muscles.Parasympathetic stimulation releases Ach at their endings which causes vasodilation. The effect is more in glands and GIT.Adrenaline acts alpha and beta receptors. It causes vasoconstriction alpha receptors in the blood vessels of the skin and mucous memb... | Physiology | Cardiovascular system |
33464687-ef6c-42cd-a759-545c75e5cd18 | Colombo plan is a plan of: | UNO | World Bank | Common Wealth countries | Government of Ceylon | 2c | single | null | Dental | null |
4177ea11-cfb6-47a3-bb2b-39c2d8ac6703 | Folic acid supplementation is necessory for - | Mensturating females | Elderly females | Pregnant females | All | 2c | multi | Ans. is 'c' i.e., Pregnant females Body stores of folate are not large, about 5-10 mg, and therefore, folate deficiency can develop quickly.Folic acid requirements are greatest in conditions where there is rapid cell multiplication, such as during growth in young children and during pregnancy.Folic acid supplementation... | Social & Preventive Medicine | null |
b30582f9-4ced-49ae-96f9-af41f395a530 | Lower border of pharynx is the level of: | C2 | C3 | C4 | C6 | 3d | single | Pharynx, the upper portion of gut tube, is funnel-shaped fibromuscular tube that extends from the base of the skull to the inferior border of the cricoid cartilage at the level of C6 vertebra.
It continues inferiorly as the esophagus. | Anatomy | null |
c1fb960c-914d-4844-a2fe-5c06e3bf5a93 | Which of the following is not a chronic myelopro liferative disorder | Polycythemia vera | Acute myeloid leukemia | CML | Essential thrombocytopenia | 1b | single | Example of mycloproliferative disorders
Polycythemia vera
1o myelofibrosis
Essential thrompocythemia
CML | Pathology | null |
07de13b2-e919-48a3-b1b3-d277d9b4b204 | Best investigation for Zenker's diverticulum is: | Barium swallow | Endoscopy | CECT | EUS | 0a | multi | Ans. (a) Barium swallowRef: Sabiston 20th Edition, Page 1020-1022* IOC for Zenker's - Barium swallow* IOC for Achalasia - Manometry* IOC for Barret's - Endoscopic biopsy | Surgery | Oesophagus |
ba6ea86b-2090-4084-a5f9-ec8fd6c746d6 | Which of the following treatment for menorrhagia is not suppoed by evidence? | Ethamsylate | Tranexamic acid | OCP | Progesterone therapy on days 5 -25 | 0a | single | Ethamsylate is known to reduce capillary fragility. Hence it is not effective for uterine bleeding which is more due to the vasodilator prostaglandins. Antiprostaglandins are used since NSAIDs reduce prostaglandin levels by inhibiting cyclooxygenase and decreasing the ratio of prostacyclin to thromboxane. Prostaglandin... | Gynaecology & Obstetrics | Normal Menstruation, Abnormal Menstruation, Menopausal Physiology and forsight of conception |
d8102fe5-4859-44c0-b2a5-78d9bf3b181a | All of the following are predominant motor neuropathy except | Acute inflammatory demyelinating polyradiculo neuropathy | Porphyric neuropathy | Lead intoxication | Arsenic intoxication | 3d | multi | Motor predominant neuropathies are immune neuropathies: acute GBS,a cute intermittent porphyria,laed neuropathy,diphtheric neuropathy,brachial neuritis-,diabetic lumbosacral plexus neuropathy,hereditarymotor-sensory neuropathy. Ref Harrison20th edition pg 2567 | Medicine | C.N.S |
638c89e0-570e-4733-9473-a109ba48ace7 | Which of the following should be avoided initially in hemorrhagic shock: March 2011 | Ringer lactate | Dextrose 5% | Normal saline | None of the above | 1b | multi | Ans. B: Dextrose 5% Hypotonic solutions (e.g. dextrose) are poor volume expanders and should not be used in the treatment of shock unless the deficit is free water loss (e.g. diabetes insipidus) or patients are sodium overloaded (e.g. cirrhosis) Glucose containing solutions should not be used in shock (they exacerbate ... | Surgery | null |
9736e667-311f-48c5-a805-f4150833afc0 | Talkativeness and flight of ideas are suggestive of - | Schizophrenia | Hysteria | Mania | Tricyclic antidepressants | 2c | single | null | Psychiatry | null |
8b80d0f4-6728-4ebd-96d4-5ff0fd5c6ad7 | Auto-splenectomy is associated with - | Systemic lupus erythematosus | Trauma | Sarcoidosis | ITP | 0a | single | Answer- A. Systemic lupus erythematosusSLE patients with thrombocytosis anil antiphospholipid sytdrome are at risk of developing autosplenectomy. | Medicine | null |
786259f4-e29b-4940-8208-eb27933dbbab | % of children with simple febrile seizures developing epilepsy is – | 1–2% | 2–5% | 5–10% | 10–20% | 0a | single | Children with febrile seizures have an increased risk of developing epilepsy.
Between 2% to 7% of all children with febrile seizures develop epilepsy if followed up to the age of 25 years. Risk depends on type of febrile seizure :
i) Simple febrile seizures →2% of all children with simple febrile seizures.
ii) Complex... | Pediatrics | null |
cda4b094-cfdb-48c6-9aa7-264d3a078df3 | The primary auditory cortex lies primarily in which lobe of the cerebral cortex? | Limbic lobe | Occipital lobe | Parietal lobe | Temporal lobe | 3d | single | Most of the primary auditory cortex is in the temporal lobe, but the association auditory cortices extend over much of the insular lobe and even onto the lateral portion of the parietal lobe. | Physiology | null |
d3a9bf42-f2a2-44c7-bebb-f1161836ad56 | Superior mesenteric aery supplies: | Colon | Anus | Rectum | Descending colon | 0a | single | Colon | Anatomy | null |
2ed6616c-1b0c-4d69-9661-74b9c6fbcc18 | Most impoant investigation for pericardial effusion - | Cardiac catheterization | USG | Echocardiography | X-ray chest | 2c | single | 2D Echocardiography is the investigation of choice for Pericardial Effusion ,Cardiac Tamponade ,Valvular Hea ds , Cardiomyopathy | Radiology | Cardiovascular system |
2e898fa3-eef9-432b-b75d-55ed17d07dd1 | Which of the following tests is not used in the diagnosis of insulinoma | Fasting blood glucose | Xylose test | C- peptide levels | Insulin /Glucose Ratio | 1b | single | Answer is B (Xylose test) : Xylose test is used in the diagnosis of malabsorption due to intestinal mucosal disease. This test is not used for the diagnosis of Insulinomas Fasting blood glucose, C- peptide levels and Insulin Glucose Ratio are all used in the diagnosis of Insulinomas. Diagnosis of Insulinomas 6,uU/m1 wh... | Medicine | null |
c83417b5-1187-49a2-a682-fa3d83770aa0 | Chances of veical transmission of Hepatitis B may be high as | 25% | 40% | 60% | 90% | 3d | single | Answer is D (90%) The rate of perinatal transmission of hepatitis B (HBV) essentially depends on the presence or absence of HBe Ag and viral replication. The rate of perinatal transmission of HBV may be as high as 90% in neonates born to mothers who are positive for HBe AG. 'The likelihood of perinatal transmission of ... | Medicine | null |
0c369ac7-6572-43c6-8f9c-64812d384024 | pO2 pressure at sea level: | 140 | 150 | 160 | 180 | 2c | single | Ans. (c) 160* At sea level the atmosphere exerts a total pressure of 760mmHg. Since the atmosphere is 21% 02 (by volume), the partial pressure of oxygen (pO,)= 0.21 x 760 = 160 mmHg.* The partial pressure of C02 (pC02) at sea level is 0.23 mmHg. | Physiology | Principles of Gas Exchange - Respiratory Membrane |
9995aac2-a7a4-45a2-b3af-5470f4bb880a | A one and a half year old child holding her father's hand slipped and fell but did not let go of her father's hand. After that she continued to cry and hold the forearm in pronated position and refused to move the affected exremity. Which of the following management of this stage is most appropriate - | Supinate the forearm | Examine the child under GA | Elevate the limb and observe | Investigate for osteomyelitis | 0a | single | This is a case of pulled elbow.
Treatment is simple. The child's attention is diverted, the elbow is quickly supinated and then slightly flexed. | Orthopaedics | null |
72c4c11d-c765-48b7-835a-97deb480fde1 | A 22 year football player came to the hospital with pain and swelling at the lateral aspect of ankle. The emergency depament diagnosed as inversion sprain. Which of the following ligament is affected ? | Calcaneonavicular | Calcaneofibular | Long plantar | Sho plantar | 1b | multi | A forced inversion of foot results in tear of calcaneofibular ligament, sometimes anterior talofibular ligament. They prevent inversion of foot Ref: Gray's Anatomy The Anatomical Basics of Clinical Practice 41 e pg 1431 | Anatomy | Lower limb |
80194c0f-6655-49ed-83ae-7b5348d85a76 | Most common nerve involvement in fracture surgical neck humerus: | Axillary nerve | Radial nerve | Ulnar nerve | Median nerve | 0a | single | A i.e. Axillary nerve Injury Common Nerve Involvement Anterior shoulder dislocation Fracture surgical neck humerus Axillary (circumflex humeral) nerveQ Axillary nerveQ Fracture shaft humerus Fracture supracondylar humerus Medial condyle humerus Radial nerveQ Radial or median nerve Ulnar nerve Monteggia fracture disloca... | Surgery | null |
f1eb0fb1-1b4a-41a6-b654-02f485fa7388 | Surgical removal of torus is indicated when | Torus impinges on soft palate | It interferes with development of proper PPS | Torus is an undercut that traps debris and food | All of the above | 3d | multi | In addition to above indications, torus should also be removed when it interferes with development of adequately extended denture or when patient is too much concerned about it. | Dental | null |
74849aec-b77c-466d-abbf-c82d054122ab | All the following are used for the detoxification of opioids except | Methadone | Clonidine | Buprenorphine | Pethidine | 3d | multi | Pethidine isn't used and methadone is most commonly used as it has v v less addiction liability and it acts slow and in uniform manner opiod withdrawl and opiod detoxification has to be read in detail opiod detoxification can be done by 3 main steps namely SYMPTOMATIC DETOXIFICATION=== using clonidine, benzodiazepam, d... | Psychiatry | Substance abuse |
7a5c2f70-d9a9-4c6e-85a6-e2d21795de88 | Which bacteria show Rotatory motility | Trichomonas | Mycoplasma | Balantidium | Borrelia | 2c | single | Balantidium coli is ciliate which shows rotatory motility. | Microbiology | null |
a677eebe-ee30-4801-9398-9ad89b518eb0 | Which among the following drains into IVC | Renal | SMV | IMV | Splenic vein | 0a | single | Ans) a (Renal) Ref BD Chaurasia AbdomenSMV joins with splenic veins to form portal veins behind neck of pancreas.IMV drains into splenic vein.Splenic vein forms portal vein with SMV. | Surgery | Miscellaneous |
17912ab1-f97f-48cc-a4e4-809706180afe | GH level increases during | REM sleep | Hypoglycaemia | Increased cortisol | Hyperglycemia | 1b | single | (B) Hypoglycaemia # Stimulators of Growth Hormone (GH) secretion include:> Peptide hormones: GHRH (somatocrinin) through binding to the growth hormone-releasing hormone receptor (GHRHR) Ghrelin through binding to growth hormone secretagogue receptors (GHSR)> Sex hormones: Increased androgen secretion during puberty (in... | Medicine | Miscellaneous |
73ec54d8-9f2f-421d-a8c1-14585e6b5351 | A 50 year old female patient complains of difficulty in swallowing. Patient gives h/o multiple diagnostic CT-scans of the head and neck region. The incidence of which of the following salivary gland tumor will be more likely in this patient? | Pleomorphic adenocarcinoma | Mucoepidermoid carcinoma | Adenoid cystic carcinoma | Acinic cell carcinoma | 1b | multi | The incidence of salivary gland tumors, both benign and malignant, is increased in patients treated with irradiation for diseases of the head and neck and in Japanese atomic bomb survivors.
Most of the tumors were benign, with Warthin tumor being the most frequent.
Among the malignant tumors, the frequency of mucoepid... | Radiology | null |
561b7a24-2f1a-43f2-a7f3-ca3e49259246 | Blood specimen for neonatal thyroid screening is obtained on - | Cord blood | 24 hours after bih | 48 hours after bih | 72 hours after bih | 0a | single | Ans. is 'a' i.e., Cord blood Neonatal thyroid screening : Guidelines by Indian Academy of Paediatrics 1.Screening should idealy be done for all newborns : because there are generally not signs or symptoms of hypothyroidism at bih. 2. Use cord blood, or wait for 5-7 days for sampling : results are difficult to interpret... | Pediatrics | null |
ed8b11a9-a2ea-4530-a8e1-329f33d64cf3 | Which is the drug of choice for malaria in a 26-year-old pregnant lady, in the first trimester? | Proguanil | Chloroquine | Aemesin | Halofantarine | 1b | single | Chloroquine is the drug of choice for prophylaxis and treatment of malaria during all phases of pregnancy. Chloroquine is a rapidly acting blood schizonticide which destroys asexual blood forms of all plasmodium species. For woman with chloroquine-resistant infection, mefloquine is given orally. | Pharmacology | null |
787a3117-4dee-46a2-9fb7-1ff555551f34 | Ideal hearing aid for patient with anotia is | Incanal | Bone anchored hearing aid | Vestibular | Transcutaneous | 1b | single | Anotia ("no ear") describes a rare, congenital deformity, that involves the complete absence of the pinna, the outer projected poion of the ear, and narrowing or absence of the ear canal. A bone-anchored hearing aid is an implantable device that allows the listener to hear by bone conduction without the inconvenience o... | ENT | null |
6cb735d1-2b84-4561-8fa5-e980cedcf3dc | Newborn loses how much weight in first week ? | 5-10% | 1-2% | 10-20% | None | 0a | multi | O.P.Ghai 9th edition - page 13 | Anatomy | General anatomy |
465aefac-a08c-4729-911d-afa06844e5c5 | Metabolism of chloramphenicol is by- | Glucuronide conjugation | Oxidation | Acetyl ation | Sulfation | 0a | single | Ans. is 'a' i.e., Glucuronide conjugation o Chloramphenicol undergoes enterohepatic circulation and is primarily conjugated with glucuronic acid in the liver. | Pharmacology | null |
dc40950e-c7df-4894-aa8a-a7f185e9d670 | Hemorrhagic cystitis is caused by - | Busulphan | Cisplatin | Cyclophosphamide | Doxorubicin | 2c | single | Ans. is 'c' i.e., Cyclophosphamide Hemorrhagic cystitis is commonly associated with CyclophosphamideCyclophocphamide is the most common cause of hemorrhagic cystitis.The drug Cyclophosphamide itself is not toxic,The drug toxicity is due to its hepatic conversion to the metabolite "acrolein" which is excreted in the uri... | Pharmacology | Adverse Drug Effect |
4368e6af-3f8f-462a-85cc-7757329e631f | Regarding Chlamydia infection of the eyes, true statement include the following except: | Mostly asymptomatic | Can be cultured | Inclusion conjunctivitis is an acute ocular infection caused by sexually transmitted C. trachomatis strains (usually serovars D through K) | Penicillin is the treatment | 3d | multi | Ans (d) Penicillin is the treatment Penicillin is not effective against Chlamydia Drugs effective against Chlamydia include - Tetracycline - Erythromycin - Azithromycin - Sulfonamides - Rifampicin Chlamydia can be cultured, but not in cell free media. In most cases trachoma inflammation undergoes spontaneous resolution... | Microbiology | null |
7827ad54-a6a0-43b4-a1cc-b46bedea46f5 | Which of following is not a schneider's first rank symptom- | Passivity phenominon | Auditory hallucinations | Delusions of self reference | Delusional perception | 2c | multi | null | Psychiatry | null |
a2d8075a-ef80-4706-9139-cbec3e5208ed | Tic douloureux is facial pain traveling through which of the following nerves - | Facial | Hypoglossal | Trigeminal | Vestibulocochlear | 2c | single | Ans. is 'c' i.e.. Trigeminal o Tic Douloureux refers to the association of Hemifacial spasm with Trieeminal Neuralgia (Trieeminal nerve)o The pain of trigeminal neuralgia tends to occur in paroxysms and is maximal at or near onset.o Facial spasma can be seen with severe pain.# This finding gave rise to the older term f... | Medicine | Cranial Nerve Disorders |
32a87d0a-c3a9-4588-ba5b-70af53eb5e53 | Incomplete casting can be due to: | Insufficient venting. | Inadequate or too small spreu. | Low casting pressure. | All of the above. | 3d | multi | Reasons for incomplete castings:
Insufficient venting
Inadequate sprue (too small sprue)
Insufficient alloy used
Alloy not sufficiently molten or fluid
Mold is not heated to casting temperature
Premature solidification of alloy
Low casting pressure | Dental | null |
19ac4efd-a40a-40c2-b1aa-e24b4cd84362 | A 75 yr. old female patient presented with microscopic haematuria with RBC casts seen in the urine. Her serum creatinine was 3.9 mg/dl. Light microscopy and Silver staining of the Kidney specimen revealed the following: Which of the following would be the most appropriate diagnosis and the site of Ig deposits? | PSGN, subepithelial deposits | Type 1 MPGN, subendothelial deposits. | Membranous GN, subepithelial deposits | IgA nephropathy, mesangial deposits | 2c | single | The light microscopy reveals uniform thickening of basement membrane which when stained with Silver stain reveals the SPIKE and DOME pattern of staining seen in membranous GN. MPGN would reveal Tram track or splitting of GBM on electron and Silver stain. PSGN would reveal large hypercellular glomerulus with subepitheli... | Unknown | Integrated QBank |
9cb8a5de-cf62-48ee-b278-5997d4068560 | Leukocyte alkaline phosphate is increased in all,except- | Polycythyemia vera | CML | Myelofibrosis | Myeloid metaplasia | 1b | multi | null | Medicine | null |
e431916e-9875-4715-a20c-6b1b7549825c | A 28-year-old man is admitted to the emergency department complaining of pain in the umbilical region that moves to the right iliac fossa. Which is a corroborative sign of acute appendicitis? | Referred pain in the right side with pressure on the left (Rovsing) sign | Increase of pain with testicular elevation | Relief of pain in lower abdomen with extension of thigh | Relief of pain in lower abdomen with internal rotation of right thigh | 0a | single | Rousing's sign is corroborative of acute appendicitis. The other signs are corroborative of appendicitis. Hyperesthesia is a useful sign provided that it is performed objectively. The area of hyperesthesia is a triangular area (base placed upward) in the right lower abdomen. | Surgery | Small & Large Intestine |
b2167534-1b55-4a86-b0ea-fa255a64e738 | Severe pain in eye with loss of vision can be a manifestation of: March 2013 (h) | Acute angle closure glaucoma | Open angle glaucoma | Vitreous hemorrhage | Retinal detachment | 0a | single | Ans. A i.e. Acute angle closure glaucoma | Ophthalmology | null |
83ac5db9-1003-40b5-b259-c1f5c7809eaf | The sacrotuberous ligament represents the origin of- | Gluteus maximus | Semimembranosus | Long head of biceps femoris | Sacrospinous ligament | 2c | single | The superficial fibers of lower part of sacrotuberous ligament continue into the tendon of long head of biceps femoris. | Anatomy | null |
78685ba7-1dbf-4091-ad93-e8e24e9a53c2 | Maximum absorption of bicarbonate occurs at | PCT | DCT | CT | ALH | 0a | single | About 67% of filtered, sodium, water, potassium, urea, 80% of filtered phosphate and bicarbonate, 100% of filtered glucose and amino acids are reabsorbed in PCT Ref: Ganong 25th ed/page 679 | Physiology | Renal physiology |
78498ad9-1d64-4b64-8a36-58345c85fd0b | IL-2 activates Th 1 /CD 4 through | NK cells | Th cells | T memory cells | All the above | 3d | multi | (D) All the above | Pathology | Misc. |
41b278cb-be90-4a29-aae4-835ad684cf90 | Lower leg perforators are named after | Cockett | Boyd | Dodd | May or kuster | 0a | single | . | Anatomy | All India exam |
7718570e-c063-41f6-a680-168027891872 | Silver tatoo is due to | deposition of Ag Amalgam in Mucosa | deposition of Ag Amalgam in Bone | deposition of Ag Amalgam in Dentin | deposition of Ag Amalgam in Enamel | 0a | single | null | Pathology | null |
899040c0-2426-4d12-9fad-99af7c624223 | An 18 year old boy while riding a motorbike without a helmet sustained a road traffic accident. He is brought to casualty and imaging studies done. He is diagnosed with left frontal skull fracture and cortical contusion. He has had no seizures and his GCS is 10. Antiepileptic drug therapy in this patient | Is contraindicated due to risk of rash | Indicated to reduce incidence of early onset post traumatic seizures | Is likely to cause increased cerebral edema | Indicated to reduce incidence of late onset post traumatic seizures | 1b | single | Prophylactic phenytoin reduces incidence of seizures after head injury, though there is no reduction in long term risk | Medicine | null |
f541cc85-851a-4dfc-8176-434327434e0e | An elderly woman suffering from Schizophrenia is on antipsychotic medication. She developed purposeless involuntary facial and limb movements, constant chewing and puffing of cheeks. Which of the following drugs is least likely to be involved in this side effect? | Haloperidol | Clozapine | Fluphenazine | Loxapine | 1b | single | The history here is suggestive of tardive dyskinesia. TARDIVE DYSKINESIA It is an EPSE of the antipsychotics Occurs months to years after staing antipsychotics Signs and symptoms: Lip smacking or chewing Tongue protrusion Choreiform hand movements Pelvic thrusting Prevalance: 5% of patients per year of antipsychotic ex... | Psychiatry | Schizophrenia Spectrum and Other Psychotic Disorders |
9ab192eb-ae4e-4eb2-9e64-362b704d2588 | Bronchospasm is not caused by | Regurgitation | Aspiration | Intubation | Halothane | 3d | single | D i.e. Halothane | Anaesthesia | null |
6bef370d-6470-404a-9d49-57e289a586d5 | Which of the following gene defect is associated with development of medullary carcinoma of thy roid- | RET Proto Oncogene | Fap gene | Rb gene | BRCA 1 gene | 0a | single | Ans. is 'a' i.e., RET proto oncogene o RET protooncogene is a growth factor receptor (receptor tyrosine kinase)o The RET protein is a receptor for the glial cell lined derived neurotrophic factor and structurally related proteins that promote cell survival during neural development,o RET is normally expressed in the fo... | Pathology | Thyroid and Parathyroid |
087606a4-a50e-45bf-90b8-d296ba71db4a | Anti leprosy drug causing ichthyoses is ? | Dapsone | Clofazamine | Rifampicin | Clarithromycin | 3d | single | Ans. is 'd' i.e., Clofazamine Acquired ichthyosis (Ichthyosis acquista) Acquired ichthyosis is seen in : ? Deficiency :- Protein, Vitamin A, Kwashiorkor, Marasmus. Infection :- Leprosy, AIDS Senile ichthyosis :- Elderly Systemic diseases :- SLE, DM, hypothyroidism, Sarcoidosis, liver & kidney diseases. Malignancy, espe... | Skin | null |
35bc9552-e542-4db5-a534-26157a22aefd | A 40yr old male presenting with URTI, hemoptysis and has elevated cANCA value is most likely having | Churg strauss syndrome | Wegner's granulomatosis | Microscopic polyangitis | Good Pasteurs syndrome | 1b | single | Ans: b) Wegner's granulomatosis Wegner's granulomatosis is a necrotizing vasculitis characterized by:i) Acute necrotizing granuloma of URT/LRTii) Necrotizing vasculitis involving small to medium vesselsiii) Renal disease - focal necrotizing crescentic glomerulitiscANCA is positive in 95% of all patients with acute gene... | Pathology | Blood Vessels |
375df9cb-8067-459b-a186-4b8af5c85e5d | Deep transverse arrest is most commonly seen in: | Android pelvis | Gynaecoid pelvis | Flat pelvis | Anthropoid pelvis | 0a | single | Android pelvis | Gynaecology & Obstetrics | null |
e437daa0-41cf-4b89-ba45-f335d91e107b | Which of the following is a naturally occuring radioactive substance in the body in small quantities? | Radium 226 | Bismuth 60 | Iodine 131 | Potassium 40 | 3d | multi | Sources of radiation exposure are: Natural sources and Manmade sources. The natural sources include cosmic rays, environmental (terrestrial and atmospheric) radiation, internal radiation (Potassium - 40 & Carbon -14) Man-made Radiation: Medical and dental: X rays, radioisotopes Occupational exposure Nuclear Misc: TV, R... | Social & Preventive Medicine | Environment and health |
12370ca6-3014-4068-b837-53f6efa3d4f7 | The selection of a pulp protecting agent does not depend on: | Remaining dentin thickness | Choice of restorative material | Symptoms of the patient | Stage of tooth development | 3d | single | The base is selected according to:
Design of the cavity
Type of permanent restorative material used
Proximity of the pulp to the cavity walls | Dental | null |
ae3ca698-45fa-4cc4-99d1-8ab247a04f51 | A 30yr old patient presented with features of acute meningoencephalitis in the casualty. His CSF on wet mount microscopy revealed motile unicellular microorganism. The most likely organism is - | Naegleria fowleri | Acanthamoeba castellani | E. histolytica | Ent. Coli | 0a | single | option-1-Naegleria fowleri: 1. Acute and fulminating primary amoebic meningoencephalitis (PAM) is caused by Naegleria fowleri. 2. Clinical features of N. fowleri: typical feature of meningitis with rhinitis are seen .The key to diagnosis is clinical suspicion based on recent history of swimming or diving in warm waters... | Microbiology | Parasitology |
ea968b2d-e830-4e97-b2a0-18cc37cedfb7 | All are true regarding tetanus except - | Transmission through contaminated wounds and injuries | More common in winters and dry weather | Reservoir in soil and intestines of human and animals | No herd immunity or life long immunity | 1b | multi | <p> Tetanus (especially NNT) has a marked seasonal incidense in India:>50% cases in July-September. Reference:Park&;s textbook of preventive and social medicine,K.Park,23rd edition,page no:310-314. <\p> | Social & Preventive Medicine | Communicable diseases |
bac077df-07fd-49eb-8bb6-49cdda70303d | Normal urea excretion rate is- | 1-2 gm per day | 10-20 gm/day | 20-40 gm per day | 50-100 gm/day | 1b | single | Ans. is 'b' i.e., 10-20 gm/day "The physiologically normal individual excrete 12-20 gm of urea nitrogen in 24 hours"* However, excretion varies according to various factors, like nutritional status, dietary intake of proteins, physical activity level etc. | Physiology | Kidneys and Body Fluids |
15c47421-df2d-4957-adf8-c5072b6f9db8 | Kidney plays a role in maintaining constancy of milieu interior. Milieu interior refers to: | ECF | ICF | Plasma | Serum | 0a | single | Milieu interior refers to the extracellular environment. The main function of kidney is homeostasis, the maintenance of the constancy of the milieu interior. Ref: Fundamentals of Medical Physiology by Joel Michael, Sabyasachi Sircar, 2010, Chapter 53. | Biochemistry | null |
d25e88e0-4be8-4bca-9946-331aa41dfffc | Follow ing is/ are the causes of chronic cough with noncontributory chest radiograph- | Asthma | Post nasal drip | GERD | All the above | 3d | multi | Ans. is 'd' i.e., All the above o 90% of patients who have chronic cough and a normal or noncontributory chest radiograph belong to one of the following causes:Use of an angiotensin-converting enzyme inhibitor;Post-nasal drainage;Gastroesophageal reflux; andAsthma. | ENT | Larynx |
c6b031c6-ff9f-40df-a4d3-a4707091c50a | Decreased O2 affinity of Hb in blood with decreased pH: | Haldane effect | Double Haldane effect | Bohr effect | Double Bohr effect | 2c | single | Ans. C. Bohr effecta. Bohr effect:i. Definition the decrease in O2 affinity of Hb when the pH of the blood falls is called the Bohr effectii. Deoxy Hb binds H+ more actively than does oxy Hb.iii. PH of blood falls as its CO2 content increases so that when the PCO2 rises the curve shifts to the right and the P50 rises t... | Physiology | Principles of Gas Exchange - Respiratory Membrane |
2b9094ce-5721-409c-9138-1cae215b7348 | The largest presenting diameter in cephalic presentation is : | Biparietal diameter | Suboccipito bregmatic | Occipito frontal | None of the above | 3d | multi | None of the above | Gynaecology & Obstetrics | null |
06de1df8-23f3-4ee1-a554-af823d865a37 | Neuro-physiological defects present in right lobe involvement are all, except | Visuo-spatial defect | Anosognosia | Dyscalculia | Dysgraphia | 2c | multi | Dyscalculia is seen in left lobe involvement, as mathematical functions are done by the left lobe. | Physiology | null |
e4ae0ae0-80dd-4b97-93a5-9360b1415f22 | Treatment of choice for Kawasaki diseae | IV immunoglobulin | Steroid | Azathioprin | Not recalled | 0a | multi | Kawasaki disease is a vasculitis that mostly involves the coronary vessels. It presents as an acute systemic disorder, usually affecting children under 5 years.Kawasaki's disease is an acute, febrile, multisystem disease of children. Some 80% of cases occur prior to the age of 5, with the peak incidence occurring at <=... | Medicine | Immune system |
a718479a-9a12-4c1c-8c24-b47f46bffe3f | Pterygium all are true except | Arise from any pa of conjunctiva | Can cause astigmatism | Surgery is treatment of choice | UV exposure is risk factor | 0a | multi | . Arise from any pa of conjunctiva Ref: AK khurana 7th ed. | Ophthalmology | All India exam |
eec9da66-6ec7-4640-84e4-a14755c9808e | Most common subtype of Rodent ulcer is: | Superficial | Cystic | Nodular | Pigmented | 2c | single | Rodent ulcer is also known as basal cell carcinoma of the skin, or tear cancer which is a slow-growing type of cancer. Types of Rodent ulcers: Nodular (90%) (MC) Pigmented Cystic Superficial The most common type being nodular which has characteristic pearly whitenodules in the periphery with centralumbilication and tel... | Surgery | FMGE 2018 |
59c2bcb9-7fc3-49dc-944a-08f740ad74a9 | Achoffs bodies in rheumatic hea disease show all of following feautures except: | Anitkshkow cells | Epitheloid cells | Giant cells | Fibrinoid necrosis | 1b | multi | Aschoff bodies consists of foci of swollen esinophilic collagen surronded by lymphocytes ocassional plasma cells and plump macrophages called anitschkow cells. These cella are also called caterpillar cells some of the larfer macrophages become multinucleated to form achoff giant cells. (ref Robbins 7th/593-594) | Anatomy | Cardiovascular system |
a2feb8db-e2de-4946-925e-db6bed8ccc18 | Wiskott Aldrich syndrome is associated with all of the following except : | Thrombocytopenia | Recurrent infections | Low levels of IgG | Deficient cell mediated immunity | 2c | multi | Answer is C (Low levels of IgG) : 'Immunoglobulin defect in Wiskott-Aldrich syndrome include low serum concentration of IgM. IgA & IgG are normal and IgE is frequently increased' - Harrison 'Serum IgM levels is low but IgG and IgA levels are normal or elevated' - Ananthnaravanan | Medicine | null |
19af1524-96e6-462e-a2f5-e96e03581887 | Heller's myotomy is done for:September 2007, 2009, 2010 | Esophageal carcinoma | Pyloric hyperophy | Achalasia cardia | Inguinal hernia | 2c | single | Ans. C: Achalasia cardiaAchalasia is associated with loss of ganglion cells in the esophageal myenteric plexus.These impoant inhibitory neurons induce LES relaxation and coordinate proximal-to-distal peristaltic contraction of the esophagusAchalasia is an esophageal motor disorder characterized by increased lower esoph... | Surgery | null |
f3c39491-f4b9-4c4b-a6b2-131a4687f798 | Pyruvate dehydrogenase is inhibited allosterically by ? | AMP | Pyruvate | NADH | `Insulin | 2c | multi | Ans. is 'c' i.e., NADH | Biochemistry | null |
aa77fb81-fe04-4d56-8fe0-281cf5110c41 | Which of the following statements about Grave’s disease is false? | Results in hyperthyroidism | Autoimmune disorder | Common in Male | Referred as Toxic diffuse goiter | 2c | multi | Ref. Sabiston Textbook of Surgery. Pg. 2819
Graves disease is an autoimmune disease caused by the presence of thyroid stimulating immunoglobulin in the plasma resulting in hyperthyroidism .
The female : male ratio ranges from 5:1 to 10:1.
Diffuse toxic goiter is the major manifestation of Graves disease.
Pathogenes... | Unknown | null |
94161515-b4d2-4d07-b2c8-0f9462a5f755 | Menorrhagea, which IUCD should be used - | CNG | CuT | Mirena | Multiload | 2c | single | Ans. is 'c' i.e., Mirena | Gynaecology & Obstetrics | Non-Hormonal - Intrauterine Devices |
59dfee46-561b-4ee1-80df-b1552b82ef1b | Japanese B encephalitis is transmitted by | Aedes | Anopheles | Culex | All of the above | 2c | multi | (C) Culex TAXONOMY OF SOME IMPORTANT ARBOVIRUSESFamilyGenusImportant speciesTogaviridaeAlphavirusChikungunya, O'nyong-nyong, Mayaro, Semliki Forest Sindbis, Ross River, Eastern, Western and Venezuelan equine encephalitis virusesFlaviviridaeFlavivirusJapanese encephalitis, Murray Valley encephalitis, WestNile, llheus, S... | Microbiology | Misc. |
b6acf207-c864-43d2-8196-02bf3e39b6f9 | Doppler ultrasound in pregnancy detect : | Cardiovascular malformation | Neural tube defect | Abdominal masses | IUGR | 3d | single | Ans. is d i.e. IUGR Doppler ultrasonography is a noninvasive technique to assess blood flow. It is useful for diagnosis of IUGR. "The utility of umbilical aery Doppler velocimetry was reviewed by the American College of obstetricians and gynecologists (1999, 2000). It was concluded that no benefit has been demonstrated... | Gynaecology & Obstetrics | null |
5c54792f-89f0-40ac-81c0-b34dd9f7c168 | A 20-year-old woman presents with a 4-week history of dry mouth, fatigue, fever, and yellow sclerae. Physical examination shows mild jaundice and hepatomegaly Serum total bilirubin is 3.3 mg/dL. Serologic markers for viral hepatitis are negative. The anti-mitochondrial antibody test is negative. A liver biopsy disclose... | Autoimmune hepatitis | Extrahepatic jaundice | Primary biliary cirrhosis | Primary sclerosing cholangitis | 0a | single | Autoimmune hepatitis is a type of chronic hepatitis, which is associated with circulating autoantibodies (e.g., antinuclear antibodies) and high levels of serum immunoglobulins. The disease typically affects young women but occasionally afflicts older women and men. It is often accompanied by other autoimmune diseases ... | Pathology | Liver & Biliary Tract |
29fd1b19-bb27-4402-815a-dc5747fce0a3 | Intrauterine death most likely results in? | Hypofibrinogenemia | Cervical tear | Sterility | All of the above | 0a | multi | Ans. A. Hypofibrinogenemia. (Ref Textbook of Obstetrics D.C. Dutta 6th Ed.344f 345)Abruption placentae is the most common cause of severe consumptive coagulopathy in obstetrics.However, Slow development of maternal hypofibrinogenemia is most important complication of IUD.Intrauterine Death (IUD)Causes of recurrent intr... | Gynaecology & Obstetrics | Miscellaneous (Gynae) |
3fcfb07e-1a4f-4886-bda9-496a43a11b1c | Brodman's area number for motor area - | 4 & 6 | 1, 2, 3 | 5 & 7 | 16 & 18 | 0a | single | Ans. is 'a' i.e., 4 & 6 * Somatosensory area - Brodmann's area 3, 1 and 2.* Motor areas (motor & premotor) - Brodmann's area 4 & 6 | Physiology | Nervous System |
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