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a8694082-1388-45fe-a7c6-c554da1b11f1 | What is indicated by the arrow in the contrast X-ray abdomen? | Gastric ulcer | GIST | Carcinoma stomach | Gastric polyp | 0a | single | A large, benign-appearing gastric ulcer protrudes medially from the lesser curvature of the stomach.Features suggesting benign gastric ulceroutpouching of ulcer crater beyond the gastric contoursmooth rounded and deep ulcer cratersmooth ulcer mound malignant gastric ulcerdoes not protrude beyond the gastric contour irr... | Surgery | G.I.T |
c85be7db-00a2-4050-8701-d75f9946e988 | Capgras syndrome is - | Sharing of delusion | Delusion of double | Erotomania | Hypochondriacal delusions | 1b | single | Ans. is 'b' i.e., Delusion of double o Capgras syndrome is delusion of double.The delusional misidentification syndrome LDSM)o DSM is characterized by misidentification delusions of other or self. Four main syndromes are differentiated : -Capgras syndrome (Delusion of double) Patient falsely sees a familiar person as a... | Psychiatry | Symptoms & Signs |
45b72887-8cc2-47a8-ab30-0eb36fad4d90 | The lingual bar connector should be located at least how many millimeters below the gingival margin? | 2 | 4 | 6 | 8 | 1b | single | null | Dental | null |
1238de64-18b9-4fd1-8376-bcc1f62826bb | Present "General feility rates" ? | 84 | 118 | 128 | 138 | 0a | single | Ans. is 'a' i.e., 84 | Social & Preventive Medicine | null |
42c9fdcb-94aa-4074-ab3b-83dfe1589e68 | A common cause of Primary hyperparathyroidism is | Multiple parathyroid adenomas | Solitary parathyroid adenoma | Adrenal hyperplasia | Ectopic PTH production | 1b | single | null | Medicine | null |
d629b9dd-5d44-4a3f-8eb3-03fa03383201 | Vit k helps in gamma-carboxylation of following AA | Glutamate | Aspaate | Glycine | Alanine | 0a | single | Vitamin k plays a role in gama carboxylation of glutamate containing proteins It is a posttransilational modification Ref:Guyton and Hall textbook of medical physiology 12th edition,page number: 20,21,22 | Physiology | General physiology |
9512507e-717f-4509-aab8-db9288f39bb1 | Infantile polycythemia is seen in – | Cerebellar haemangioma | Retinoblastoma | Hepatoblastoma | All | 0a | multi | In pediatrics, polycythemia is usually secondary to chronic hypoxia.
Secondary causes of pediatric polycythemia
Cyanotic congenital heart disease o Brain tumor (Cerebellar hematzgioma)
Chronic pulmonary disease --> Cystic fibrosis o Cushing disease
High altit... | Pediatrics | null |
a38a457c-ccf3-41f8-8f91-453da431cbf2 | Not a feature of CBD stone: | Pain | Fever | Jaundice | Septic shock | 3d | single | Ans. (d) Septic shock* Septic Shock happens only when Charcot's triad of Cholangitis is not properly managed* Charcot's triad + Septic Shock + Altered mental Status = Reynauld's Pentad | Surgery | Gall Bladder & Bile Ducts |
17069d9d-fe16-46e5-aafa-f006a941cc8c | True about intracellular receptor | Mainly on nuclear surface | Estrogen does not act on it | GH acts on it | Vitamin E act on these | 0a | multi | Interacellular receptors are mainly present on nuclear surface They are eeceptors for peptide hormones Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:540,541,542 | Physiology | General physiology |
d455534c-591e-4dea-ae47-5273ccefdc3a | Which of the following is supplied by the abdominal aorta? | Accessory lung lobes | Bronchopulmonary segment | Sequestrated lung tissue | Base of lung | 2c | single | Normally the lung tissue is not supplied by aorta. But, when an abnormal lung tissue persists from the embryonic life, this tissue is known as a sequestrated lung tissue. It may be covered by its own pleura when existing outside the lung, or may lie within the lung. The blood supply to this tissue is by an abnormal bra... | Anatomy | null |
dc677ee1-37f5-40a6-b3b2-76a952a9d4d6 | Pulse steroid therapy can be given in - | Pemphigus vulgaris | Acute renal allograft rejection | Optic neuritis | All the above | 3d | multi | Ans. is 'd' i.e., All the above Pulse Steroid therapy* Pulse therapy means the administration of suprapharmacologic doses of drugs in an intermittent manner to enhance the therapeutic effect and reduce the side effects.* In context of corticosteroids, pulse therapy refers to discontinuous i.v. infusion of high doses of... | Pharmacology | Miscellaneous (Pharmacology) |
dd1f2fff-3db8-4de4-b648-06ed851c7820 | Which of the following is true about xeroderma pigmentosa? | Autosomal dominant | Good long term prognosis | Purine dimmers | DNA repair defect | 3d | multi | Ans. is 'd' i.e., DNA repair defect Xeroderma pigmentosaA. Molecular defect: - Exposure to UV rays damages DNA due to production of convalent linkages between adjacent pyrimidines (pyrimidine dimmers). Normally the damaged DNA is repaired by excision and repair. In xeroderma pigmentosa the repair of UV damaged DNA is d... | Skin | Miscellaneous |
f50f1167-5879-45a4-a9cb-dfef4229c659 | About papillary carcinoma what is true | Often encapsulated | Prognosis bad | Lymph node metastases is common | Iodine deficiency is a impoant risk factor | 2c | multi | Papillary thyroid cancer is most common thyroid cancer and has the best prognosis. Not commonly encapsulated. Spreads commonly by lymphatic route. Irradiation is the impoant risk factor . Iodine deficieny is a impoant risk factor for follicular cancer. Source : Sabiston 20th edition Pg : 902 | Surgery | Endocrinology and breast |
c07dce71-e024-4048-9652-9fbc331d0828 | When ohotoludine reagent is added to water and if free chuirine is present, what colour will be produced? | Pink | Yellow | Green | Red | 1b | single | Ans. is 'b' i.e., Yellow | Social & Preventive Medicine | null |
876e8ee0-9852-449b-a3c0-5c63321ee412 | TRUE/FALSE about pulmonary embolism: McConnell sign is seen in CT pulmonary angiography as a filling defect. Westermark sign is area of regional oligemia seen on x-ray. Polo mint sign is seen in echocardiography as regional motion abnormality. IOC in pregnant patient is V/Q scan. Chang sign is abrupt change in diameter... | FTFTT | FTTFT | FTTTT | FFTFT | 0a | multi | Pulmonary thromboembolism - Hampton hump sign- Peripheral wedge-shapedarea of infarction - Westermark sign - Pulmonary oligemia - Pallas sign - Prominence of descending right pulmonary aery - Fleischner sign- Prominence of main pulmonary aery - Chang sign - abrupt change in caliber of the descendingright pulmonary aery... | Radiology | Radiology Q Bank |
8112d770-523d-4866-bcb7-08324cdca5e9 | A serious adverse effect seen with zoledronate is? | Anterior uveitis | Ventricular fibrillation | Peptic ulcer | Acute renal failure | 3d | single | Zoledronate Intravenous 3rd generation bisphosphonateseffective in the management of hypercalcemia Rapid normalization of S. Ca2+ S/E - Severe hypocalcemia Renal toxicity, Osteonecrosis of the jaw | Pharmacology | Osteoporosis, Sex Hormones and OCPs |
84072ff9-f01e-4194-ad29-ee1b2922d4b7 | Which of the following HPV type is most carcinogenic - | 6 | 11 | 16 | 3 | 2c | single | Ans. is 'c' i.e., 16 * High risk HPV: HPV-16, 18, 31, 33 & 45 - associated with cervical cancer.* Low risk HPV: HPV- 6 & 11 - associated with precursor lesions CIN* HPV-5 & 8 - associated with squamous cell cancer in patients with epidermodysplasia verruciformis. | Microbiology | Virology |
1ad30097-42be-447d-8346-5f81acd51b37 | Oral lesions of secondary syphilis includes all EXCEPT | Snail track ulcers | Mucous patches | Chancre of tongue | Hutchinson's wart | 2c | multi | null | Pathology | null |
34fe54b8-8be6-4af9-be37-35fc69f5b564 | Best antihypeensive drug used in pulmonary hypeension is: | Digoxin | Furosemide | Amlodipine | Bosentan | 3d | single | Ans: D. Bosentan(Ref Harrison 19/e p1659, 18/e p2079)Treatment of Pulmonary Aerial HypeensionEndothelin-Receptor AntagonistsBosentan & ambrisentan are approved for the treatments of Bosentan is contraindicated in patients who are on cyclosporine or glyburide concurrently.Phosphodiesterase-5 InhibitorsSildenafil and tad... | Pharmacology | null |
76c132d1-2b23-4bbc-81f8-a8d3ce9176a6 | All are liver glycogenosis except? | Von Girke disease | Hers disease | Type IIi glycogenosis | Pompes disease | 3d | multi | Ans. is 'd' i.e., Pompes disease | Pediatrics | null |
112776a0-47f1-4ab7-b459-f70fd2b849ac | Evaluation of screening test is by - | Sensitivity | Specificity | Predictive value | All the above | 3d | multi | null | Social & Preventive Medicine | null |
6da9aa3b-78ee-416d-b874-1d8ee4d3bcdc | "Rosette-shaped cataract" is seen in: | Trauma | Diabetes Mellitus | Hypertension | Complicated cataract | 0a | single | Ans. A. Trauma. (Ref Parsons' diseases of Eye 21th/pg. 383)WOUNDS OF THE LENS:If the trauma to lens is small, the entry of aqueous causes a localized cloudiness in its vicinity and, irrrespective of the site of the wound, opacities in the form of feathery lines appear in the posterior cortex, which later develop into a... | Ophthalmology | Lens |
43060827-dd95-4c5f-b09e-a6dfbbba493c | Which of the following is best associated with lumefantrine | Antimycobacterial | Antifungal | Antimalarial | Antiamoebic | 2c | single | Refer KDT 6/e p795 Like halofantrine, lumefantrine, is also used for the treatment of malaria | Pharmacology | Chemotherapy |
e45af944-0b8d-443c-8246-7c007f7a01cf | Regarding testicular tumour, the following are false except - | They are commonest malignancy in older man | Seminomas are radiosensitive | Only 25% of Stage 1 teratomas are cured by surgery alone. | Chemotherapy rarely produces a cure in those with metastatic disease | 1b | multi | Seminomas are well known to be one of the most radiosensitive tumors
About other options
Option (a) : Commonest malignancy in older males is → Prostate cancer
Option (c) : Stage I Nonseminomas (including teratomas) are t/t by surgery alone and show a high cure rate (>95%)
Option (d) : Chemotherapy shows a good res... | Surgery | null |
360a6ef6-dc96-4890-946b-a65d23c5660a | Skeletal Muscle relaxant of choice in Liver and Hepatic Failure is: | Gallamine | Thiopentone | Atracurium | Lignocaine | 2c | multi | Atracurium | Anaesthesia | null |
75a93852-8268-45f4-aab5-ea31beace58b | A 56 year old Type II diabetic presents with complaints of swelling in the left ankle with effusion but only minimal pain. X-rays show severe osteopenia with bone destruction, extensive osteophytosis and loose bodies. The management of this patient includes all the following except: | Resting and Splinting | Aspiration and Compression bandage | Total Ankle Replacement | Ankle ahrodesis | 2c | multi | Swelling in the ankle with effusion, minimal pain together with the given x-ray findings suggests the diagnosis of neuropathic joint disease or charcot's joint. Total ankle replacement is an absolute contraindication in the management of charcot's joint. Ref: Total Ankle Ahroplasty By Hintermann, 2005, Page 92; Apley's... | Surgery | null |
053fb9e9-274b-4b71-9299-f2335317243d | "Blow out" fracture of orbit involve - | Floor | Medial wall | Lateral wall | Roof | 0a | multi | These generally result from blunt trauma to the orbit by a large object such as a cricket ball, tennis ball, human fist. The force of the blow causes a backward displacement of the eyeball and an increase in the intraorbital pressure; with a resultant fracture at the weakest point of the orbital wall. Usually this poin... | Ophthalmology | Ocular trauma |
74b0a4e1-460e-4f81-88cc-adac83549d8e | Kamino bodies are seen in | Lichen planus | Hailey-Hailey disease | Lichenoid tissue reaction | Spitz nevus | 3d | single | Kamino bodies are the eosinophilic globules seen in Spitz nevus( it is benign melanocytic nevus, a type of skin lesion, affecting the epidermis and dermis) | Dental | Hyper Pigmented Disorders |
d93c9065-02c5-4c98-9fa9-003bf34faaa7 | Calcification in necrotic tissue is called - | Dystrophic calcification | Metastatic calcification | Calcinosis | Tumoral calcicosis | 0a | multi | Amyloidosis is the extracellular deposition of insoluble protein fibrils.
AL- Primary systemic amyloidosis
AA- Secondary amyloidosis
AF- Familial
Aβ2M- In ESRD
Diagnosed by abdominal fat pad aspiration showing apple green birefringence by polarized light microscopy with Congo red stain
High ESR, High ALP
Serum Immunofi... | Pathology | null |
695dc9cb-b1ba-4b87-912a-22868187ec6f | Conjunctival epithelium is – | Pseudostratified | Stratified columnar | Stratified non keratinized squamous | Transitional | 2c | single | The epithelial lining of the conjunctiva is stratified non-keratinized epithelium, the thickness of which vary from region to region maximum at limbal conjunctiva (8 to 10 layered) and minimum at tarsal conjunctiva (2 layered). | Ophthalmology | null |
06872bfd-110a-4dda-9a42-da9a234aad1e | Stye is inflammation of ? | Zeis' gland | Meibomian gland | Glands of Manz | Lacrimal glands | 0a | single | Ans. is 'a' i.e., Zeis' gland | Ophthalmology | null |
8c24f09d-a3a5-4d0c-9724-1c042b2777fc | Which among the following is the abductor of vocal cord, paralysis of which could lead to suffocation? | Posterior cricoarytenoid | Cricothyroid | Lateral cricoaretynoid | Interarytenoid | 0a | single | Posterior cricoarytenoid is the sole abductor of vocal cords and bilateral paralysis may lead to the adduction of vocal cords and suffocation. The posterior cricoarytenoid muscle causes the muscular process of the arytenoid to be pulled posteriorly and toward the opposite arytenoid. The vocal process, in turn, is pulle... | ENT | null |
77d8f097-e30b-4a8c-9143-40e2e4d58567 | In which of the following intensive management of diabetes needed except- | Autonomicneuropathycausing postural hypotension | Pregnancy | Post kidney transplant in diabetic nephropathy | DM with acute MI | 3d | multi | Ans is option 4 - DM with acute neuropathy. Cardiovascular disease is increased in patients with diabetes but there is no evidence to suggest that improved glycemic control with intensive management reduces cardiovascular complications in DM Indications for intensive DM management are:- Healthy adults with either type ... | Medicine | Endocrinology |
9e41b83d-64bb-422e-bc29-cd29fb1f31b5 | A patient is presenting to the emergency room with abrupt onset of motor symptoms. The neurology resident is unable to correlate the presentation and a concrete neurological diagnosis. It also appears that the patient is not very concerned about his own symptoms. This is called: | Labile affect | Labelle indifference | Affecting blunting | Incongruent affect | 1b | multi | 1. La belle indifference Inappropriate attitude of calm or lack of concern about one's disability Seen in Dissociative or conversion disorders 2. Labile Affect Rapid and abrupt changes in emotion largely unrelated to external stimuli most commonly seen in mania 3. Affective blunting Severe reduction in the intensity of... | Psychiatry | Neurotic, Stress Related and Somatoform Disorders |
477dcb2f-72ee-4eea-9e4f-8b50e1ff6f00 | Maximal reduction in gastric acidity is achieved by: | Truncal vagotomy and pyloroplasty | Truncal vagotomy and antrectomy | Paial gastrectomy | Highly selective vagotomy | 1b | single | Truncal vagotomy and antrectomy is procedure of choice for recurrent duodenal ulcers with lowest recurrence rate. | Surgery | Stomach & Duodenum |
475fd648-1e4b-448d-8fa3-d8abd430bdd6 | False about p53 is- | It is present on chromosomes 17 | It causes cell cylce arrest in G1 | 53 KDa | Non mutated wild p53 is associated with neoplasm in childhood | 3d | multi | p53 is the protein produced by TP53, guardian of human genome. It stimulates cells for DNA repair and in anti onco genic.Basic Pathology, Robbins. Page no.:185 | Pathology | General pathology |
06931592-2319-42fb-b2cf-c1b620754799 | Conjunctival mucosal overgrowth over cornea? | Pterygium | Pingecula | Vernal keratoconjunctivitis | Herbe's pit | 0a | single | Ans. is 'a' i.e., Pterygium Pterygium Pterygium is a non-cancerous (non-neoplastic) growth of conjunctiva, characterized by a wing-shaped fold of conjunctiva encroaching upon the cornea from either side within the interpalpebral fissure. Pterygium is always situated in the palpebral apeure. Pathologically Pterygium is ... | Ophthalmology | null |
a85ad6a8-de38-4629-9a37-f765969980a4 | The latent period in distraction osteogenesis is | 4-6 weeks | 5-7 days | 6-8 months | 4 months | 1b | single | null | Surgery | null |
ab315004-d2a6-4272-ba8d-08ac3948bb97 | The instrument used in | laparoscopic sterilization | removal of ectopic | myomectomy | Endometrial polypectomy | 0a | single | REF : SHAW GYNECOLOGY | Gynaecology & Obstetrics | All India exam |
2874488b-b00a-42f5-95ff-56b3c491c698 | Patient presents with inability to conve pyruvate to Acetyl CoA. Which of the following can be given in treatment:- | Vitamin B3 | Thiamine B1 | Free fatty acids | Biotin | 1b | single | PDH COMPLEX - three enzymes (1 ) pyruvate dehydrogenase (E1), (2) dihydrolipoyl transacetylase (E2) (3) dihydrolipoyl dehydrogenase (E3) FIVE COENZYME - VITAMIN B1 , B2 , B3 , B5 , COA, LIPOIC ACID Any oxidative decarboxylation reaction in body require vitamin B1 so here answer is the vitamin b1 | Biochemistry | JIPMER 2018 |
b489644c-4245-4ad8-9ff5-d7f31f2d4d77 | Earliest change in atherosclerosis is | Fatty streaks | Fibrofatty plaque | Calcification | Gelatinous lesions | 0a | single | A. i.e. (Fatty streaks) (385- 86 - Harsh Mohan 5th) (349 - Basic pathology 8th)ATHEROSCLEROSIS - is an intima- based lesion organized into a fibrous cap and an atheromatous (gruel- like) core and composed by smooth muscle cells, endothelial cells inflammatory cells, lipids and necrotic debris* Atherosclerosis is a slow... | Pathology | Blood Vessels |
63cc582b-f4a0-41fb-956b-435a13a691d0 | Lynch syndrome is associated with cancers of the | Breast ,colon, ovary | Breast , endometrium, ovary | Breast ,colon,endometrium | Colon,endometrium ,ovary | 3d | single | Ref Harrison 17/e p575; Robbins 8/e p821- 822; 9/e p 810 Lynch syndrome is an autosomal dominant disorder it is called as hereditary non polyposis colon cancer It is caused because of defective DNA repair genes leading to micro satellite instability There is increased chances of multiple cancer such as colorectal cance... | Anatomy | General anatomy |
dfc1776a-2e89-423b-a2b9-92920ec49749 | In indirect ophthalmoscopy the examining eye is made: | Myopic | Hypermetropic | Emmetropic | None of the above | 0a | multi | Ans. Myopic | Ophthalmology | null |
dd53bca2-4e50-4d8b-bc48-66addc37a5e4 | Morbilliform eruptions is seen in | Rubella | Scarlet fever | Mumps | Toxic shock syndrome | 3d | single | A morbilliform rash is a rose-red flat (macular) or slightly elevated (maculopapular) eruption, showing circular or elliptical lesions varying in diameter from 1 to 3 mm, with healthy-looking skin intervening seen in toxic shock syndrome Ref Harrison20th edition pg 1334 | Dental | Bacterial infections |
dac5a3f6-cd8f-4183-95bf-7d3c1f49f88b | Bence - Jones are laboratory finding of | Paget's disease | Multiple myeloma | Malignant melanoma | Fibrous dysplasia | 1b | single | null | Pathology | null |
dc0a8889-6a6f-4fb7-b17e-26319ca4620b | Human developmental index includes all except: | Adult literacy rate | Per capita income | Life expectancy | Infant moality rate | 3d | multi | PQL I ( physical quality of life index) HDI ( human development index) 1) Literacy rate 1) Literacy rate 2) Infant moality rate 2) Income 3) Life expectancy at 1 year of age 3) life expectancy at bih. 4) 0<PQ LI < 100 4) 0< HDI < +1 | Social & Preventive Medicine | JIPMER 2019 |
872967c3-a644-4647-8288-bb759bba7213 | Risk factor for malignant melanoma all the following are risk factors fore malignant melanoma except | Giant congenital nevi | Family history melanoma | Exposure to UV light | HPV infection | 3d | multi | Answer- D. HPV infectionrisk factor for malignant melanoma is exposure to (UV radiation)Dysplastic nevus (DN) syndrome; 5-10% risk of forming superficial spreading mil*o^u.Xeroderma pigmentosumHistoryon nonmelanoma skin cancer (NMSC)Family history of melanoma (high risk)Congenital nevi | Surgery | null |
d9340ff1-3c31-45b1-930f-afe996808aac | Which of the following findings most strongly indicates a sizable intra-abdominal hemorrhage in a ruptured ectopic pregnancy? | Shoulder pain | Nausea and vomiting | Heavy vaginal bleeding | Unilateral lower abdominal pain | 0a | single | Symptoms and signs of Ectopic pregnancy - "Classical" cases are characterized by variably delayed menstruation followed by slight vaginal bleeding or spotting. With rupture, there is usually severe lower abdominal and pelvic pain that is frequently described as sharp, stabbing, or tearing, while the patient may also pr... | Gynaecology & Obstetrics | Ectopic Pregnancy (Hello ! Where are you ?) |
bd920415-1ca2-4054-a36a-13d1f3c34d58 | Dusehene muscular dystrophy true - | Autosomal dominant | Onset at second decade of life | Universal increase in creatine kinase | Normal cardiac muscle fibre. | 2c | multi | Ans. is 'c' i.e., Universal increase in creatine kinase Duchenne and Becker's muscular dystrophy are X-like recessive.o So expression of gene is essentially confirmed in males.o Females are affected only if X-chromosome carrying the normal allele is lost or inactivatedo Becker is milder form with late onset and slow pr... | Pediatrics | Disorders of Muscle and Muscular Dystrophies |
c16e023e-e083-4c1b-aa2b-914ffeac6278 | Patient presenting with marked loin pain, tenderness and pyrexia shows nonspecific findings on IVP but on US reveals a heterogeneous mass with posterior acoustic enhancement and central necrosis and internal debris. CT shows marginal enhancement with air densities within. The likely diagnosis is: | Emphysematous pyelonephritis | Pyonephrosis | Renal abscess | Acute pyelonephritis | 2c | single | Renal abscess Presence of air, rim enhancement on CT and posterio acoustic enhancement in a focal mass with acute clinical history is suggestive of an abscess. | Surgery | null |
cebedd08-5ffd-47b6-ba96-fc80f73fe93d | Posterior relation of neck of pancreas ? | IVC | Origin of postal vein | Aoa | Common bile duct | 1b | single | Ans. is 'b' i.e., Origin of poal vein | Anatomy | null |
1a9686f5-ac75-4b43-8170-5d748e371302 | Ketamine should be avoided in: | The presence of increased aerial pressure | Pregnancy | Hypovolemic shock | Asthmatic | 0a | single | Ketamine should be avoided in hypeension,CCF, cerebral hemorrhage,increased intra cranial tension, psychiatric disorders and pregnancy before term. Ketamine causes increase in HR,CO and BP. From padmaja 4th edition Page no 196 | Pharmacology | Anesthesia |
e0bd1f9c-a3ec-4386-8bfe-6fafca5eed42 | Characteristic radiological feature of fibrous dysplasia | Thickened bone matrix | Cortical erosion | Ground glass appearance | Bone enlargement | 2c | single | Ans is 'c' i.e. Ground glass appearance "In long bones, the fibrous dysplastic lesions are typically well-defined, radiolucent areas with thin cortices and a ground-glass appearance "- HarrisonFibrous DysplasiaIt is characterized by the replacement of normal lamellar cancellous bone by an abnormal fibrous tissue that c... | Orthopaedics | Bone Tumour |
971b31fa-9ef7-4e2d-86bd-bbf64b79e9a8 | All of the following are the known causes of osteoporosis except - | Fluorosis | Hypogonadism | Hypehyroidism | Hyperparathyroidism | 0a | multi | Osteoporosis It refers to reduction ofbone mass per unit volume (loss of matrix and defective mineralisation) (Fig. 9.47). Aetiology 1.Involutional 2.Endocrinological 3.Gastrointestinal 4.Haematological 5.Rheumatological 6.Collagen vascular Normal bone Type I (postmenopausal) and Type II (senile) Hypehyroidism Hyperpar... | Medicine | Endocrinology |
44fdd172-0713-4d10-b023-669b7545f8a7 | If CVS sampling is done at 9 - 10 weeks what will happen- | NTD | Fetal loss | Limb defect | Vaginal bleeding | 2c | single | Ans. is 'c' i.e., limb defect o When CVS performed at less than Id weeks of gestation there is a high incidence of limb reduction defects.Chorionic villus sampling (CVS)o Performed for prenatal diagnosis of genetic disorderso It is carried out transcervically between 10 - 12 weeks and transabdominally from 10 weeks to ... | Unknown | null |
faa4bbf6-9985-40be-acf7-972e5597dc46 | Which of the following can be given in hepatic as well as in renal failure | Atracurium | Vecuronium | Pancuronium | Mivacurium | 0a | single | Atracurium and Cis-atracurium are the muscle relaxants of choice in both liver and renal failure. Atracurium is inactivated by Hoffman's elimination and alkaline ester hydrolysis. Cis-atracurium is eliminated by Hoffman's elimination. Hence atracurium and cis-Atracurium duration of action is not altered in patients wit... | Anaesthesia | Muscle relaxants |
82a028d1-ce52-42e7-849e-8a01e63c154b | Patisiran was approved by FDA recently for | Filariasis | Peripheral Neuropathy | Neuropathy of diabetes | Neuropathy of amyloidosis | 3d | single | It is a double stranded small interfering ribose neuclic acid ( si RNA) formulated in the form of a lipid complex. used in the treatment of polyneuropathy | Pharmacology | All India exam |
d158f534-d70c-4631-abb1-a6f9e598e5fc | Which of the following infection is diagnosed by aldehyde test? | Fasciola hepatica | Leishmania | Toxoplasma | Toxocara canis | 1b | single | Formol-gel test or (Napier's aldehyde test) and Chopra's antimony test are useful in the diagnosis of chronic kala-azar. The gel-test is performed by the addition of two drops of commercial formalin to 2 ml of patient's serum in a test tube; the mixture is shaken and allowed to stand at room temperature. If there is op... | Microbiology | null |
2848b5f5-ef35-4d50-9d95-da87203e02aa | NOT a feature of post-traumatic stress disorder: AI 08; JIPMER 13; NIMHANS 14 | Hyperarousal | Emotional numbing | Flashbacks | Hallucinations | 3d | multi | Ans. Hallucinations | Forensic Medicine | null |
c14fc7ab-6363-4c58-a9b8-7782dc090887 | Most common cause of death after Total Hip Replacement is- DELETE | Infection | Pneumonia | Anemia | Thromboembolism | 3d | single | *Thromboembolic disease is the most common cause of death after total hip replacement. REF:Ref:Ohopaedics secrets 3rd/e p.34 | Anatomy | null |
17e5e135-0eb4-4a32-9899-54bc469f698f | Myeloid sarcoma, which is tumor mass consisting of myeloid blasts occurring at anatomic sites other than bone marrow, are often characterized by chromosome aberrations all, EXCEPT: | Monosomy 7 | Trisomy 8 | inv (16) | t (15;17) | 3d | multi | In AML Patients may present with symptoms from a myeloid sarcoma that is a tumor mass consisting of myeloid blasts occurring at anatomic sites other than bone marrow. This rare presentation, often characterized by chromosome aberrations may precede or coincide with AML. Ref: Harrisons Principles of Internal Medicine, 1... | Medicine | null |
85b05ce2-1cb9-4da2-a4e0-6034bee16db2 | Most common manifestation of mumps in adult males - | Aseptic meningitis | Encephalitis | Orchitis | Sinusitis | 2c | single | Ans. is 'c' i. e., Orchitis o Orchiyid is the most common manifestation of mumps among postpubertal males | Social & Preventive Medicine | Communicable Diseases |
b4317e14-387d-4032-b86e-c27a21639fb8 | Metabolites in HMP shunt are all except | Glycerol–3 phosphate | Sedoheptulose–7 phosphate | Glyceraldehyde–3 phosphate | Xylulose–5 phosphate | 0a | multi | Glycerol-3 phosphate
Glyceraldehyde-3-phosphate is produced (not glycerol-3-phosphate).
Metabolites in HMP shunt
Oxidative phase:- Glucose-6-phosphate → 6-phosphogluconate → Ribulose-5-phosphate.
Non-oxidatative phase :- Xylulose-5-phosphate, Ribose-5-phosphate, sedoheptulose-7-phosphate, erythrose-4-phosphate, fruct... | Biochemistry | null |
f276b35c-83c8-42de-8c34-68d0329b4a1a | SGLT 2 is found in | Liver | Intestine | Spleen | None of the above | 3d | multi | It is present in kidney SGLT1 is present in intestine They actively absorbe glucose | Anatomy | General anatomy |
ad291cf5-89ce-40cf-88ef-e0830ca191d9 | Ultrasound and radionuclids studies are primary imaging modalities used for assessment of - | Renal trauma | Renovascular hypertension | Renal tuberculosis | Renal transplant | 3d | single | null | Medicine | null |
c454c3ed-9180-479f-8ed2-1ffb834effb8 | Not true about Vi polysaccharide vaccine of typhoid: | Single dose is given | Revaccination at 3 years | Given at bih | Given subcutaneously | 2c | multi | Ans. is. 'c' i. e., Given at bih | Microbiology | null |
136e8831-2c48-4e01-a30b-583115426c0d | Which of the following statement regarding C-reactive protein is false? | It is increased in pneumococcal infection | It is an acute phase substance | The gene for the protein is on Chromosome 14 | Can be raised after a surgery | 2c | multi | The gene for CRP is on chromosome 1. CRP is an abnormal protein which appear in blood in response to inflammatory cytokines such as IL 6. It is one of the most sensitive acute pahse reactant. It is elevated following severe trauma, bacterial infections, inflammation, surgery or neoplastic proliferation. | Biochemistry | null |
c7b10481-5688-4f04-b912-fff8d4488f5d | Investigation of choice for intramedullary SOL is – | MRI | USG | CT | X–ray | 0a | single | Investigation of choice for intramedullary space occupy lesion is MRI. | Radiology | null |
32ef2e58-2536-4169-b85b-dbd020a3b965 | Which of following is the most common site for extranodal lymphoma? | Esophagus | Stomach | Intestine | Skin | 1b | single | Although extranodal lymphomas can arise in viually any tissue they di so most commonly in the GI tract paicularly the stomach.(ref Robbins 9th/773) | Anatomy | Haematology |
feb137ac-a60d-488e-b78b-8867ae657ea2 | A surgical resident has accidently given an intra aerial injection of thiopental sodium to a patient on the ward. The arm has blanched below the level of the injection. Which of the following is NOT recommended for the management? | Immediately remove the needle and apply warm towel | Perform a brachial plexus block on the affected side | Give IV heparin | Give analgesics | 0a | single | The recommendation in such a scenario is to leave the needle in the aery and to inject a vasodilator like papaverine. A brachial plexus block or stellate ganglion block will cause vasodilatation and decrease the ischemia. In case of extravascular injection infiltrate with hyaluronidase 1500 IU dissolved in 1 ml through... | Surgery | null |
dcc5b065-cf8e-47b4-9c02-b671e65a3bf9 | Sympathectomy of the kidney results in which of the following responses? | No change to the glomerular filtration rate, nor to the urine output | Decreased urine output | Reduction of glomerular filtration rate and decreased urinary output | Increased urine output | 3d | single | The kidney is innervated primarily by the sympathetic nervous system and as such, regulates the contraction of the smooth muscle surrounding the afferent and efferent aerioles of the glomerulus. Sympathetic stimulation to the efferent glomerular aerioles causes the constriction and increases the filtration rate, leadin... | Physiology | null |
2052beff-a5e8-4155-a18a-741d3c565690 | Prophylactic therapy should be started against Pneumocystis carinii pneumonia in AIDS patients with CD4 counts below : | < 50/microL | < 150/ microL | < 200/ microL | < 400/ microL | 2c | single | null | Pharmacology | null |
55cfde3d-274a-42bb-a068-20da8f4808df | Reversible injury in myocardium occurs at ? | 2 minutes | 30 minutes | 2 hours | 5 hours | 1b | single | Ans. is 'b' i.e., 30 minuteso The metabolic rate of the hea is high, and its stores of substrate are low.o So, hea is critically dependent on a continuous supply of oxygen and nutrients.o Ischemia of myocardium induces profound functional, biochemical and morphological consequences.o Myocardial function is more sensiti... | Pathology | null |
70e2a739-d582-4b77-b767-b543fcb438ed | Radial tuberosity provides attachment to - | Brachialis | Biceps brachii | Triceps | Coracobrachialis | 1b | single | Ans. is 'b' i.e., Biceps brachii (Ref: Elsevier's integrated anatomy Vol 2 p 30).An anterior, rough poion of tubercle - For inseion of tendon of biceps brachii.A posterior smooth poions of tubercle - Bursa interposed between tendon & bone.. | Anatomy | null |
e3a32ec2-d0de-4659-a2b0-81c9159ccb89 | Pack year means | 10 cigarettes per day for 1 year | 20 cigarettes per day for 1 year | 40 cigarettes per day for 1 year | 50 cigarettes per day for 1 year | 1b | single | (B) 20 cigarettes per day for 1 year# A pack-year is a quantification of cigarette smoking.> 1 pack-year is equal to smoking 20 cigarettes (1 pack) per day for 1 year, or 40 cigarettes per day for half a year, and so on.> Number of pack-years = (packs smoked per day) * (years as a smoker). | Social & Preventive Medicine | Miscellaneous |
ed9c0080-fa15-4d8c-810e-91e2ef9384a0 | Asbestosis is usually related to -a) Small cell carcinoma lungb) Large cell carcinoma lungc) Mesotheliomad) Squamous cell carcinoma lung | cd | bc | bd | ac | 0a | multi | null | Medicine | null |
1f0da2f2-10dc-4bf0-a16e-771fae428505 | A person presents with following parameters PCO3- 30 mm of Hg, P02- 105 mm of Hg, pH-7.45 is having paially compensated | Metabolic acidosis | Metabolic alkalosis | Respiratory acidosis | Respiratory alkalosis | 3d | multi | Ans. d. Respiratory alkalosis In the question, pH is 7.45 and PCO, is 30 mm Hg. Overall change is slightly alkaline. Respiratory change is also alkaline. So the diagnosis is respiratory alkalosis Acid Base Disorders pH < 7.35 is acidosis; pH >7.45 is alkalosis 1degchange in HCO3 is termed as Metabolic (Normal HCO3= 22-... | Medicine | null |
1fe0ce4f-d2d3-47fa-96d4-64981ca1e805 | All of the following can cause SLE like syndrome except- | INH | Penicillin | Hydralazine | Sulphonamide | 1b | multi | null | Medicine | null |
3832949a-347d-4b43-8323-ab3e4d425e31 | What is true of fetal hematopoiesis in the course of pregnancy? | Rise in MCV | Rise in reticulocyte count | Rise in Hemoglobin content | Decrease in blood volume | 2c | multi | Fetal hematopoiesis: yolk sac - fetal liver - fetal bone marrow. The first fetal erythrocytes are nucleated and macrocytic. MCV is 180 fL and normally decreases to 105 to 115 fL. As the fetus grows, the blood volume in fetoplacental circulation increases. The fetalhemoglobin concentration increases from 12 gm/dL in mid... | Gynaecology & Obstetrics | Fetal circulation |
fb99a431-7486-4fbf-8292-587afc4cc765 | Most effective HDL raising drug is: | Omega three fatty acids | Niacin | Fenofibrate | Rosuvastatin | 1b | single | Niacin is the most effective HDL raising drug currently available. Niacin is the only drug currently available that lowers Lipoproteinp(a), and can be considered as an addition to a statin in patient with elevated Lp(a). Statins have a modest HDL-raising effect (5-10%). Fibrates are the most effective drugs available f... | Medicine | null |
f6d39c29-05cd-4d87-9ed4-ac4ca6eaa910 | True about tubercular otitis media are all except? | Spreads through eustachian tube | Causes painless ear discharge | May cause multiple perforations | Usually affects both ears | 3d | multi | Ans. is 'd' i.e., Usually affects both ears Tubercular otitis media Tuberculosis of middle ear is a comparatively rare entity usually seen in association with or secondary to pulmonary tuberculosis, infection reaches the middle ear through eustachian tube. The rare modes of infection are through hematogenous spread fro... | ENT | null |
e4a9431a-217d-4db2-8b48-16b67a67694f | Cranial pa of accessory nerve supplies all palatal muscles, EXCEPT? | Palatoglossus | Palato pharyngeus | Tensor veli palatini | Tensor veli tympani | 2c | multi | The cranial root of the accessory nerve is smaller than the spinal root. It exits the skull through the jugular foramen and unites for a sho distance with the spinal root. Its fibers innervate the pharyngeal and palatal muscles, except tensor veli palatini. | Anatomy | null |
f607be04-93c1-4cd9-8b21-6f28f460dc26 | Storage form of thyroid hormone - | Tri-iodo tyrosine | Tri - iodo tyronine | Thyroglobulin | Di-iodo thyrosine | 2c | single | null | Medicine | null |
c8fe0982-44dd-4bee-ac49-746231ec93f2 | Which of these can be safely stopped before an abdominal surgery | ACE inhibitors | Beta blockers | Statins | Steroids | 0a | single | Refer CMDT6 2014/45 All antihypeensives should be continued in preoperative period except ACE inhibitors ,angiotensin receptor blockers and diuretics ACE inhibitors and ARBs should be stopped 24 hrs before surgery to prevent intraoperative hypotension Diuretics should be stopped once the patient is kept NPO to prevent ... | Pharmacology | Anesthesia |
39d9d781-e0ef-4c65-a29a-bb136223b21a | Incision used in thyroidectomy | Barking incision | Collar incision | Kocher incision | Koebner incision | 1b | single | null | Surgery | null |
51aefe67-8701-44ee-abc5-5b5971e3e5c9 | The bodies of spine are biconcave and are called "codfish spine" most commonly seen in: | Scurvy | Osteomalacia | Fluorosis | Hyperparathyroidism | 1b | multi | Codfish Veebra is seen in 1. Osteoporosis > Osteomalacia 2. Sickle cell disease 3. Hereditary spherocytosis 4. Homocystinuria 5. Renal osteodystrophy 6. Osteogenesis imperfecta 7. Gaucher's disease | Orthopaedics | Metabolic Disorders of Bone |
b4abffe6-3a0d-455b-a855-03bacb936ad6 | Percentage of pheochromocytoma that are bilateral is: | <1% | 1-5% | 10% | 25% | 2c | single | Pheochromocytomas often are called the 10 percent tumor because 10% are bilateral, 10% are malignant, 10% occur in pediatric patients, 10% are extra-adrenal, and 10% are familial. Ref: Schwaz's principle of surgery 9th edition, chapter 38. | Surgery | null |
decbd81a-47be-4b5a-9922-41cb1429c5c3 | Fredrich's ataxia is caused by - | Point mutation | Expanded trinucleotide repeat | Missense mutation | Inversion | 1b | single | Ans. is 'b' i.e., Expanded trinucleotide repeat o Freidrich ataxia is an autosomal recessive disorder.o It is caused by loss of Junctional mutation in frataxin gene (FxN) gene.o Frataxin gene is located on chromosome 9ql3.o Majority of patients have an expanded trinucleotide repeat in intron 1 of both alleles of fratax... | Medicine | Ataxic Disorders |
d9deb788-6d10-4fa7-9050-7de9e14514a6 | Left sided sixth nerve palsy would lead to - | Accommodation paresis of left eye | Ptosis of left eye | Adduction weakness of left eye | Diplopia in left gaze | 3d | single | Left sided 6th nerve palsy lead to diplopia in left sided gaze. The abducens nerve is a nerve that controls the movement of the lateral rectus muscle in humans, responsible for outward gaze. It is also known as the abducent nerve, the sixth cranial nerve, sixth nerve Ref khurana 6/e | Ophthalmology | Ocular motility and squint |
9709175a-cc64-478d-b489-3ae8e3ae584e | Polymer of fructose | Dextrose | Cellulose | Inulin | Glycogen | 2c | single | Ans. c (Inulin) (Ref. Ganong.-23rd/Ch. 38. 26th/pg. 105).Substances Used to Measure GFRIn addition to the requirement that it be freely filtered and neither reabsorbed nor secreted in the tubules, a substance suitable for measuring the GFR should be nontoxic and not metabolized by the body. Inulin, a polymer of fructos... | Biochemistry | Carbohydrates |
eb8ad812-82e8-405f-a493-85cc7a3627ef | Global eradication of smallpox was done on: | 26th Oct 1977 | 8th May 1980 | 17th March 1980 | 17th April 1977 | 1b | multi | Ans. (b) 8th May 1980* Last indigenous case of Smallpox in India: 77th May 1975* Last case of Smallpox in India: 24th May 1975* India declared Smallpox-free: 23 April 1977* Last case of Smallpox globally: 26th October 1977 (Somalia)* Actual last case of smallpox : 1978* Global eradication of Smallpox: 8th May 1980 | Social & Preventive Medicine | Miscellaneous |
bbe52684-9774-4d93-bc0a-dbc472a9d111 | The HIV virus can be transmitted by the following routes, except - | Homosexual contact | Intact skin | Maternofoetal | Needle prick | 1b | multi | null | Surgery | null |
23fd9fcf-a6cb-4dc4-b18b-2a20502d749e | Natural light causes all except | Vitamin D synthesis | Destroys organ of coi | | Bilirubin level | Melanin synthesis | 1b | multi | Organ of Coi - A specialized structure located on the inner surface of the basilar membrane of the cochlea containing hair cells thattransmit sound vibrations to the nerve fibers.Ref: Ganong&;s review of medical physiology; 24th edition; page no: 200 | Physiology | Endocrinology |
2c5e5b38-2122-42bb-bd07-9ccaa7ef3a3f | Indicator of Remote contamination of water | Fecal Streptococci | Clostridium Perfirengens | E. Coli | Salmonella Typhi | 1b | single | Bacteriological Indicators of Water Quality E Coli: Best indicator. Ideally water should be coliform free except large urban water supplies where up to 5% contamination is acceptable if samples are taken up to 1year. For this screening test used is presumptive coliform count, MPN (Most Probable Number) and multiple tub... | Social & Preventive Medicine | Water |
ea3a3676-f9ff-4613-a472-824008ea8e8c | Vocal cord is lined by which of the following epithelium | Cuboid | Stratified squamous | Stratified columnar | Pseudo ciliated columnar | 1b | single | The epithelium of the mucous membrane of the larynx is ciliated columnar epithelium except for the vocal cords and upper pa of the vestibule where it is of stratified squamous type | Anatomy | General anatomy |
f0b19d32-f049-4fc5-b068-fa224e40cb9d | Waist to hip ratio which indicates obesity in men? | > 0.5 | 0.85 | > 0.93 | > 1.0 | 3d | single | Ans. is 'd' i.e., > 1.0Waist-Height ratio (WHtR): It is the best indicator of cardiovascular risk. It is independent of age and sex. Cut-off value is 0.5. | Social & Preventive Medicine | null |
ee90209d-d3bb-44a2-9cad-d490fc4190c7 | Type of sampling shown in Figure is | Simple random sampling | Systematic random sampling | Stratified random sampling | Cluster random sampling | 0a | single | Ans- A Simple random sampling Ref - Review: Simple Random Sampling Do you remember how simple random sampling works? Visually, it's just numbering each individual and randomly selecting a certain number of them. Here's the image we used in the previous section: Stratified Sampling Stratified sampling is different. With... | Unknown | null |
2ef8597a-6554-49a8-8f90-02af98342283 | All of the following statement about heparin are true except - | Causes alopecia | Non teratogenic | Releases lipoprotein lipase | Causes hypokalemia | 3d | multi | Ans. is 'd' i.e., Causes hypokalemia o Heparin can cause alopecia o Heparin does not cross placenta ---> nonteratogenic o Heparin releases lipoprotein lipase from vessel wall. o Heparin causes hyperkalemia (not hypokalemia). | Pharmacology | null |
9b665f12-83c2-4229-83e6-7d720dcb0dc4 | Which of the following syndromes is best associated with congenital hea disease | Lesch-Nyhan syndrome | Rasumussen syndrome | Holt oram syndrome | LEOPARD syndrome | 2c | single | Holt oram charge association syndrome is a autosomal dominant disease characterized by Cardiac lesion( ostium secundum ASD,VSD,TOF, pulmonary stenosis), coloboma, choanal atresia,genital hypoplasia,ear abnormalities,growth retardation due to TBX5 mutation Lesch nyhan syndrome/ juvenile gout is associated with self muti... | Pediatrics | C.V.S |
00f452c1-800d-4eda-991c-a23ca463c3dc | A patient has complaint of seeing coloured holoes in the evening and blurring of vision for last few days with normal 10P ? | Prodromal phase of acute angle closure glaucoma | Acute angle closure glaucoma | Chronic glaucoma | Epidemic dropsy | 0a | single | Ans. is 'a' i.e., Prodromal phase of acute angle closure glaucoma Features of latent PACG (Prodromal stage) are :? Shallow anterior chamber Occasionally complain of halos around light Sometimes slight-haziness or blurring of vision Normal 10P It is the only phase of glaucoma, where IOP pressure is normal at all the tim... | Ophthalmology | null |
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