Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Migraine MLT-down: an unusual presentation of migraine in patients with aspartame-triggered headaches. | Aspartame, an artificial sweetener added to many foods and beverages, may trigger headaches in susceptible individuals. We report two patients with aspartame-triggered attacks in whom the use of an aspartame-containing acute medication (Maxalt-MLT) worsened an ongoing attack of migraine. | ['Adolescent', 'Adult', 'Aspartame', 'Female', 'Humans', 'Male', 'Migraine Disorders', 'Serotonin Receptor Agonists', 'Sweetening Agents', 'Triazoles', 'Tryptamines'] | 11,703,479 | [['M01.060.057'], ['M01.060.116'], ['D12.644.456.345.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.546.399.750'], ['D27.505.519.625.850.800', 'D27.505.696.577.850.800'], ['D27.720.372.300.353.609', 'G07.203.300.514.500.400.700', 'J02.500.514.500.400.700'], ['D03.383.129.799'], ['D02.092.211.215.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. | Kruppel-like factor 5 (Klf5) is a transcription factor expressed by embryonic endodermal progenitors that form the lining of the gastrointestinal tract. A Klf5 floxed allele was efficiently deleted from the intestinal epithelium by a Cre transgene under control of the Shh promoter resulting in the inhibition of villus ... | ['Animals', 'Cell Differentiation', 'Cell Proliferation', 'DNA-Binding Proteins', 'Gene Deletion', 'Gene Expression Profiling', 'Gene Expression Regulation, Developmental', 'Gene Regulatory Networks', 'Hepatocyte Nuclear Factor 3-alpha', 'Intestinal Mucosa', 'Kruppel-Like Transcription Factors', 'Mice', 'Microvilli', '... | 23,266,329 | [['B01.050'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.776.260'], ['G05.365.590.762.320', 'G05.558.800.320'], ['E05.393.332'], ['G05.308.310'], ['G05.360.080.689.360'], ['D12.776.260.262.750', 'D12.776.260.950.249.500', 'D12.776.660.352.750', 'D12.776.930.318.750', 'D12.776.930.977.249.500'], ['A03.55... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Organization and adhesive properties of the hyaluronan pericellular coat of chondrocytes and epithelial cells. | Hyaluronan is a megadalton glycosaminoglycan composed of repeating units of D-N-acetylglucosamine-beta-D-Glucuronic acid. It is known to form a highly hydrated pericellular coat around chondrocytes, fibrosarcoma, and smooth muscle cells. Using environmental scanning electron microscopy we detected fully hydrated hyalur... | ['Animals', 'Cell Adhesion', 'Cell Line', 'Chondrocytes', 'Epithelial Cells', 'Glycosaminoglycans', 'Hyaluronic Acid', 'Hyaluronoglucosaminidase', 'Hydrogen-Ion Concentration', 'Microscopy, Electron, Scanning', 'Microscopy, Phase-Contrast', 'Protein Binding', 'Rats', 'Stress, Mechanical', 'Time Factors', 'Water', 'Xeno... | 12,944,312 | [['B01.050'], ['G04.022'], ['A11.251.210'], ['A11.329.171'], ['A11.436'], ['D09.698.373'], ['D09.698.373.475'], ['D08.811.277.450.529', 'D08.811.520.241.700.675'], ['G02.300'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E01.370.350.515.513.569', 'E05.490.630.569', 'E05.595.513.569'], ['G02.111.679', 'G03.808'], ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Occurrence of renal tubular dysfunction in lupus nephritis. | We prospectively evaluated 30 patients who presented with active systemic lupus erythematosus (SLE) for the presence of tubular abnormalities. All patients fulfilled the American Rheumatology Association criteria for SLE. When appropriate, a renal biopsy was performed. Of the 30 patients studied, 12 had no abnormal tub... | ['Acidosis, Renal Tubular', 'Adult', 'Ammonium Chloride', 'Bicarbonates', 'Female', 'Humans', 'Hyperkalemia', 'Kidney', 'Kidney Tubules', 'Lupus Nephritis', 'Male', 'Prospective Studies', 'Sodium', 'Sodium Bicarbonate', 'Sulfates'] | 3,034,179 | [['C12.777.419.815.093', 'C13.351.968.419.815.093', 'C16.320.831.093', 'C18.452.076.176.210'], ['M01.060.116'], ['D01.210.450.150.050', 'D01.625.062.249'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.950.396'], ['A05.810.453'], ['A05.810.453.736.560'], ... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Soil biochemical properties and stabilisation of soil organic matter in relation to deadwood of different species. | Despite the increasing number of studies on deadwood, we still have limited knowledge of its dynamics. The aim of this study was to examine the effect of deadwood on the biochemical properties of soil and stabilisation of soil organic matter (SOM). The investigation was carried out in the Czarna R?zga Reserve in Centra... | ['Humic Substances', 'Poland', 'Soil', 'Trees', 'Wood'] | 30,668,687 | [['D02.241.444', 'D02.455.426.559.389.657.377', 'D20.721.500'], ['Z01.542.248.679'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['B01.650.915'], ['A18.450.500.500', 'J01.637.241.900']] | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
[Management of short-term absence in a hospital : empirical investigations for implementation of an intervention protocol]. | Short-term absence is an important cost factor and its impact is a challenge for all management levels. In this study the effectiveness of a supportive intervention scheme for the reduction of hospital short-term absenteeism is demonstrated. Short-term absenteeism is defined here as being away from the working place fo... | ['Absenteeism', 'Cost-Benefit Analysis', 'Costs and Cost Analysis', 'Hospital Administration', 'Hospital Units', 'Humans', 'Personnel Administration, Hospital', 'Personnel, Hospital', 'Workforce'] | 20,458,454 | [['F02.784.692.107'], ['N03.219.151.125'], ['N03.219.151'], ['H02.309', 'N02.278.216.500', 'N04.452.442.452'], ['N02.278.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.216.500.968.565', 'N04.452.442.452.422.565', 'N04.452.677.440'], ['M01.526.485.740', 'N02.360.740'], ['N04.452.525']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular cloning and expression of ribosome releasing factor. | Ribosome releasing factor (RRF) is responsible for the release of ribosomes from messenger RNA at the termination of Escherichia coli protein biosynthesis (Hirashima, A., and Kaji, A. (1972) Biochemistry 11, 4037-4044). RRF has been partially analyzed by Edman degradation to obtain its amino acid sequence. Based on thi... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Base Sequence', 'Blotting, Southern', 'Cloning, Molecular', 'Escherichia coli', 'Gene Expression', 'Genes, Bacterial', 'Models, Molecular', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'Oligonucleotide Probes', 'Peptide Fragments', 'Plasmids', 'Proteins', 'RNA, ... | 2,684,966 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['E05.393.220'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.297'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of single and dual physical modifications on pinh?o starch. | Pinh?o starch was modified by annealing (ANN), heat-moisture (HMT) or sonication (SNT) treatments. The starch was also modified by a combination of these treatments (ANN-HMT, ANN-SNT, HMT-ANN, HMT-SNT, SNT-ANN, SNT-HMT). Whole starch and debranched starch fractions were analyzed by gel-permeation chromatography. Moreov... | ['Crystallization', 'Hot Temperature', 'Microscopy, Electron, Scanning', 'Molecular Weight', 'Sonication', 'Starch', 'Thermodynamics', 'Tracheophyta', 'Viscosity'] | 25,977,003 | [['E05.196.300', 'G02.171'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['G02.494'], ['E05.848'], ['D05.750.078.562.855', 'D09.301.915', 'D09.698.365.855'], ['G01.906'], ['B01.65... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Monosodium urate burden assessed with dual-energy computed tomography predicts the risk of flares in gout: a 12-month observational study : MSU burden and risk of gout flare. | BACKGROUND: Predicting the risk of flares in patients with gout is a challenge and the link between urate burden and the risk of gout flare is unclear. The objective of this study was to determine if the extent of monosodium urate (MSU) burden measured with dual-energy computed tomography (DECT) and ultrasonography (US... | ['Absorptiometry, Photon', 'Aged', 'Aged, 80 and over', 'Cost of Illness', 'Female', 'Follow-Up Studies', 'Gout', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Prospective Studies', 'Risk Factors', 'Symptom Flare Up', 'Time Factors', 'Tomography, X-Ray Computed', 'Uric Acid'] | 30,223,875 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C05.550.114.423', 'C05.550.354.500', 'C05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Marchiafava-Bignami disease. Premortem diagnosis of an acute case utilizing magnetic resonance imaging. | Marchiafava-Bignami disease is a rare demyelinating disease involving the corpus callosum and other central white matter tracts. In the patient described here, the disease produced extensive demyelination of the corpus callosum and deep cerebral white matter. This widespread demyelination, confirmed pathologically, was... | ['Acute Disease', 'Adult', 'Alcoholism', 'Brain', 'Brain Diseases', 'Corpus Callosum', 'Demyelinating Diseases', 'Humans', 'Magnetic Resonance Imaging', 'Male'] | 8,186,525 | [['C23.550.291.125'], ['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['A08.186.211'], ['C10.228.140'], ['A08.186.211.200.885.800.750'], ['C10.314'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500']] | ['Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Real time monitoring of sickle cell hemoglobin fiber formation by UV resonance Raman spectroscopy. | In sickle cell hemoglobin, individual tetramers associate into long fibers as a consequence of the mutation at the beta6 position. In this study UV resonance Raman spectroscopy is used to monitor the formation of Hb S fibers in real time through aromatic amino acid vibrational modes. The intermolecular contact formed b... | ['Amino Acid Substitution', 'Anemia, Sickle Cell', 'Crystallography, X-Ray', 'Hemoglobin, Sickle', 'Hemolysis', 'Humans', 'Kinetics', 'Models, Molecular', 'Mutation', 'Phenylalanine', 'Protein Conformation', 'Protein Subunits', 'Spectrum Analysis, Raman', 'Tryptophan', 'Tyrosine'] | 19,778,007 | [['E05.393.420.601.035', 'G05.558.109'], ['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['E05.196.309.742.225'], ['D12.776.124.400.463.588', 'D12.776.422.316.762.426.588'], ['C23.550.403', 'G12.122.545'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.49... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A test of the hierarchical model of litter decomposition. | Our basic understanding of plant litter decomposition informs the assumptions underlying widely applied soil biogeochemical models, including those embedded in Earth system models. Confidence in projected carbon cycle-climate feedbacks therefore depends on accurate knowledge about the controls regulating the rate at wh... | ['Carbon Cycle', 'Climate', 'Climate Change', 'Europe', 'Models, Theoretical', 'Soil Microbiology'] | 29,133,902 | [['G02.607.125', 'G16.500.150'], ['G16.500.275.071', 'N06.230.300.100.250'], ['G16.500.175.374'], ['Z01.542'], ['E05.599'], ['H01.158.273.540.274.555', 'N06.850.425.300']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Extravascular lung water. | Extravascular lung water (idQw1) is measured in vivo from the difference in mean transit times, computed by extrapolating the dilution curves, of two indicators, one freely diffusible, the other confined to the intravascular space. Using 3H2O it has been shown that idQw1 is smaller than the amount of extravascular wate... | ['Capillary Permeability', 'Humans', 'Pulmonary Diffusing Capacity', 'Pulmonary Edema', 'Radionuclide Imaging', 'Respiratory Distress Syndrome', 'Thermodilution', 'Tritium'] | 3,609,066 | [['G03.143.330', 'G09.330.165'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.700.650.650', 'G09.772.600'], ['C08.381.742'], ['E01.370.350.710', 'E01.370.384.730'], ['C08.381.840', 'C08.618.840'], ['E05.484.750'], ['D01.268.406.875', 'D01.362.340.875', 'D01.496.749.925']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Asymptomatic methaemoglobinaemia and its implications. | Anaesthetists are well trained to detect subtle skin signs of life-threatening situations such as cyanosis in hypoxia. However, cyanosis resulting from drug-induced, asymptomatic methaemoglobinaemia is rare and is likely to go undetected preoperatively. Patients presenting with asymptomatic methaemoglobinaemia may, the... | ['Cyanosis', 'Dapsone', 'Humans', 'Intraoperative Complications', 'Leprostatic Agents', 'Male', 'Methemoglobinemia', 'Middle Aged'] | 9,689,284 | [['C23.888.248'], ['D02.886.590.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.505'], ['D27.505.954.122.085.777'], ['C15.378.619'], ['M01.060.116.630']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Abnormal pulmonary function and associated risk factors in children and adolescents with sickle cell anemia. | Obstructive and restrictive pulmonary changes develop in children with sickle cell disease, but reports conflict as to the type of change that predominates. We prospectively performed spirometry, plethysmography, and lung diffusing capacity in 146 children aged 7 to 20 years with hemoglobin SS or Sâ(0)-thalassemia. Nin... | ['Adolescent', 'Adult', 'Airway Obstruction', 'Anemia, Sickle Cell', 'Asthma', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Forced Expiratory Volume', 'Humans', 'Lung', 'Male', 'Prognosis', 'Prospective Studies', 'Respiratory Function Tests', 'Respiratory Physiological Phenomena', 'Risk Factors', 'Young... | 24,309,610 | [['M01.060.057'], ['M01.060.116'], ['C08.618.846.185'], ['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.85... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Improvement in use of anticoagulation therapy in patients with ischemic stroke: results from Get With The Guidelines-Stroke. | BACKGROUND: Anticoagulation therapy reduces thromboembolic events in patients with atrial fibrillation (AF) and has a class I indication for ischemic stroke patients with AF and no contraindications. We determined the patient and hospital level characteristics associated with an increased use of anticoagulation, includ... | ['Aged', 'Anticoagulants', 'Atrial Fibrillation', 'Female', 'Humans', 'Ischemic Attack, Transient', 'Male', 'Stroke'] | 21,982,662 | [['M01.060.116.100'], ['D27.505.954.502.119'], ['C14.280.067.198', 'C23.550.073.198'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.150.836', 'C14.907.253.092.836'], ['C10.228.140.300.775', 'C14.907.253.855']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Toxicity of the chemiluminescent material Cyalume in anatomic assessment of the nasolacrimal system. | One of the most intriguing recent ideas for anatomic assessment of the nasolacrimal system is the use of chemiluminescence, whereby the entire system can be made visible in the physician's office. The potential toxicity of the chemiluminescent material Cyalume was evaluated through a clinical and pathological study of ... | ['Animals', 'Fluorescent Dyes', 'Hydrogen Peroxide', 'Lacrimal Apparatus', 'Nasolacrimal Duct', 'Phthalic Acids', 'Rabbits', 'Radiography'] | 6,871,791 | [['B01.050'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['A09.371.463', 'A10.336.422'], ['A09.371.463.640'], ['D02.241.223.805'], ['B01.050.150.900.649.313.968.700'], ['E01.370.350.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of long term outcome of patients with rheumatoid arthritis presenting with undifferentiated arthritis or with rheumatoid arthritis: an observational cohort study. | BACKGROUND: The outcome of undifferentiated arthritis (UA) ranges from remission to rheumatoid arthritis (RA) fulfilling the American College of Rheumatology (ACR) classification criteria.OBJECTIVES: To report the outcome of UA after 1 year of follow up and compare the disease course of patients who presented with UA, ... | ['Adult', 'Aged', 'Antirheumatic Agents', 'Arthritis', 'Arthritis, Rheumatoid', 'Disease Progression', 'Drug Utilization', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Patient Dropouts', 'Prognosis', 'Radiography', 'Severity of Illness Index', 'Statistics, Nonparametric', 'Treatment Outcome'] | 15,901,632 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.329'], ['C05.550.114'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['C23.550.291.656'], ['N04.452.706.477'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Computational discovery of transcriptional regulatory rules. | MOTIVATION: Even in a simple organism like yeast Saccharomyces cerevisiae, transcription is an extremely complex process. The expression of sets of genes can be turned on or off by the binding of specific transcription factors to the promoter regions of genes. Experimental and computational approaches have been propose... | ['Base Sequence', 'Binding Sites', 'Chromosome Mapping', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Molecular Sequence Data', 'Promoter Regions, Genetic', 'Protein Binding', 'Regulatory Sequences, Nucleic Acid', 'Sequence Analysis, DNA', 'Transcription Factors', 'Transcription, Genetic'] | 16,204,087 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['E05.393.183'], ['E05.393.332'], ['G05.308'], ['L01.453.245.667'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['G02.111.679', 'G03.808'], ['G02.111.570.080.689', 'G05.360.080.689'], ['E05.393.76... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Risk factors for urinary incontinence in Turkish women. A cross-sectional study. | OBJECTIVE: To explore the association between conventional risk factors and urinary leakage among a random sample of adult Turkish women.METHODS: Six hundred and fifty patients (mean age 33.2 +/- 10.6 years; range 17-65 years) attending 6 Primary Health Care Centers in the Eastern Marmara Region, Turkey were randomly e... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Body Mass Index', 'Cesarean Section', 'Confidence Intervals', 'Delivery, Obstetric', 'Female', 'Humans', 'Informed Consent', 'Logistic Models', 'Middle Aged', 'Odds Ratio', 'Parity', 'Pregnancy', 'Prevalence', 'Risk Factors', 'Surveys and Questionnaires', 'Turkey', 'Urina... | 17,106,542 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E04.520.252.500'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E04.520.252'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
In situ observation of oxidation of liquid droplets of tin and melting behavior of a tin particle covered with a tin oxide layer. | Oxidation of a liquid droplet of tin (Sn) was observed using an in situ specimen heating holder in an oxygen environment. The surface of the Sn liquid droplet was covered with a tin oxide layer, Sn(3)O(4), the thickness of which depended on the oxygen pressure and temperature. Subsequent cooling of the droplet resulted... | ['Freezing', 'Nanoparticles', 'Oxidation-Reduction', 'Oxides', 'Oxygen', 'Phase Transition', 'Temperature', 'Tin'] | 19,156,703 | [['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['J01.637.512.600'], ['G02.700', 'G03.295.531'], ['D01.248.497.158.685', 'D01.650.550'], ['D01.268.185.550', 'D01.362.670'], ['G01.645', 'G02.734'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
A comparative subjective assessment study of PENNSAID® and Voltaren Gel®, two topical formulations of diclofenac sodium. | Osteoarthritis (OA) is a chronic degenerative joint disease that is debilitating for many individuals. While oral nonsteroidal anti-inflammatory drugs (NSAIDs) remain a common and effective treatment approach to managing OA, concerns over cardiovascular and gastrointestinal adverse events can potentially limit their us... | ['Administration, Topical', 'Adult', 'Aged', 'Analysis of Variance', 'Anti-Inflammatory Agents, Non-Steroidal', 'Chemistry, Pharmaceutical', 'Diclofenac', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Male', 'Middle Aged', 'Osteoarthritis', 'Severity of Illness Index', 'Single-Blind Method'] | 20,854,305 | [['E02.319.267.120'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['H01.158.703.007', 'H01.181.466'], ['D02.241.223.601.210'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
A new, brief questionnaire (PEQ) developed in primary health care for measuring patients' experience of interaction, emotion and consultation outcome. | BACKGROUND: A deepened understanding of patients' perspectives is essential in order to improve medical communication. By changing focus from patient satisfaction to patient experiences, more immediate, personal and affective responses may be captured.OBJECTIVE: Our aim was to develop a new consultation-specific questi... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Factor Analysis, Statistical', 'Female', 'Focus Groups', 'Health Care Surveys', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Norway', 'Patient Satisfaction', 'Physician-Patient Relations', 'Primary Health Care', 'Psychometrics', 'Surveys ... | 11,477,049 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Unicycle injuries in the United States. | BACKGROUND: Unicycles are single-wheel machines ridden for transportation or recreation. To our knowledge, no studies have been performed that describe injury rates of unicycle use.OBJECTIVE: The objective of this study was to describe the epidemiological characteristics of unicycle injuries treated in United States (U... | ['Adolescent', 'Adult', 'Age Distribution', 'Child', 'Child, Preschool', 'Craniocerebral Trauma', 'Emergency Service, Hospital', 'Female', 'Fractures, Bone', 'Hospitalization', 'Humans', 'Joint Dislocations', 'Lacerations', 'Lower Extremity', 'Male', 'Middle Aged', 'Recreation', 'Retrospective Studies', 'Sprains and St... | 23,871,477 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.406'], ['M01.060.406.448'], ['C10.900.300', 'C26.915.300'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['C26.404'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.11... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The primary structure of rat ribosomal protein L17. | The amino acid sequence of the rat 60S ribosomal subunit protein L17 was deduced from the sequence of nucleotides in two recombinant cDNAs. Ribosomal protein L17 has 184 amino acids and has a molecular weight of 21,383. Hybridization of the cDNA to digests of nuclear DNA suggests that there are 17-19 copies of the L17 ... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Escherichia coli', 'Gene Library', 'Halobacterium', 'Humans', 'Molecular Sequence Data', 'Open Reading Frames', 'Rats', 'Ribosomal Proteins', 'Saccharomyces cerevisiae', 'Sequence Homology, Nucleic Acid'] | 2,069,571 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.325'], ['B02.200.400.400.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['G05.360.335.760.640', 'G05.360.34... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Development of sequence-characterized amplified regions (SCARs) from amplified fragment length polymorphism (AFLP) markers tightly linked to the Vf gene in apple. | Amplified fragment length polymorphism (AFLP) markers have become widely used in saturating the region of a gene of interest for the ultimate goal of map-based cloning of the gene or for marker-assisted selection. However, conversion of AFLP markers into restriction fragment length polymorphism (RFLP) or polymerase cha... | ['Base Sequence', 'Cloning, Molecular', 'DNA Primers', 'Genes, Plant', 'Genetic Linkage', 'Genetic Markers', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Rosales'] | 11,269,357 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.348'], ['D23.101.387', 'G05.695.450'], ['E05.393.620.500'], ['G05.365.795'], ['B01.650.940.800.575.912.250.859.937']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Design of O-acetylserine sulfhydrylase inhibitors by mimicking nature. | The inhibition of cysteine biosynthesis in prokaryotes and protozoa has been proposed to be relevant for the development of antibiotics. Haemophilus influenzae O-acetylserine sulfhydrylase (OASS), catalyzing l-cysteine formation, is inhibited by the insertion of the C-terminal pentapeptide (MNLNI) of serine acetyltrans... | ['Catalytic Domain', 'Computational Biology', 'Computer Simulation', 'Crystallography, X-Ray', 'Cysteine Synthase', 'Drug Design', 'Enzyme Inhibitors', 'Haemophilus influenzae', 'Models, Chemical', 'Models, Molecular', 'Molecular Structure', 'Oligopeptides', 'Structure-Activity Relationship'] | 19,928,859 | [['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['H01.158.273.180', 'L01.313.124'], ['L01.224.160'], ['E05.196.309.742.225'], ['D08.811.913.225.224'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['D27.505.519.389'], ['B03.440.450.600.450.330', 'B03.660.250.550.290.330'], ['E05.599.49... | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
The glutamyl binding site of trypanothione reductase from Crithidia fasciculata: enzyme kinetic properties of gamma-glutamyl-modified substrate analogues. | Trypanothione reductase, central to the redox defense systems of parasitic trypanosomes and leishmanias, is sufficiently different in its substrate-specificity from mammalian glutathione reductase to represent an attractive target for chemotherapeutic intervention. Previous studies of the physiological substrates trypa... | ['Amino Acid Sequence', 'Animals', 'Binding Sites', 'Crithidia fasciculata', 'Glutamates', 'Glutamic Acid', 'Glutathione', 'Glutathione Reductase', 'Kinetics', 'Molecular Sequence Data', 'NADH, NADPH Oxidoreductases', 'Spermidine', 'Substrate Specificity'] | 8,105,896 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['B01.268.475.868.110.350'], ['D12.125.067.625', 'D12.125.119.409'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['D12.644.456.448'], ['D08.811.682.667.092'], ['G01.374.661', 'G02.111.490'], ['L01.453.245.667'], ['D08.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Homicide perpetrated by older people. | OBJECTIVE: This study aims to describe the circumstances in which older people commit homicide, the form of assessment they undergo and to examine the proportion of those who suffer from mental illness.METHODS: The study was carried out as part of the England and Wales National Confidential Inquiry into Suicide and Hom... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'England', 'Female', 'Homicide', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Sex Factors', 'Spouses', 'Wales'] | 22,912,344 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.542.363.300'], ['I01.198.240.470', 'I01.880.735.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.060.116.630'], ['N05.715.350.675', 'N06.850.490.875'], ['F01.829.263.500.660', 'I01.880.853.150.500.670', 'M... | ['Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Post-transcriptional suppression of cytosolic ascorbate peroxidase expression during pathogen-induced programmed cell death in tobacco. | As a means to eliminate pathogen-infected cells and prevent diseases, programmed cell death (PCD) appears to be a defense strategy employed by most multicellular organisms. Recent studies have indicated that reactive oxygen species, such as O2.- and H2O2, play a central role in the activation and propagation of pathoge... | ['Acetates', 'Apoptosis', 'Ascorbate Peroxidases', 'Cyclopentanes', 'Cytosol', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Plant', 'Hydrogen Peroxide', 'Isoenzymes', 'Oxylipins', 'Peroxidases', 'Plant Diseases', 'Plant Growth Regulators', 'Plants, Toxic', 'Polyribosomes', 'Pseudomonas', 'RNA... | 9,501,118 | [['D02.241.081.018', 'D10.251.400.045'], ['G04.146.954.035'], ['D08.811.682.732.165'], ['D02.455.426.392.368.450'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['G05.308.320'], ['G05.308.375'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Perineurial cells coexpress genes encoding interstitial collagens and basement membrane zone components. | Perineurial cell cultures were established from the sciatic nerves of adult Wistar rats. Highly enriched cultures were studied with respect to the production of extracellular matrix components under conditions free from the influence of Schwann cells, axons, or the extracellular matrix of peripheral nerves. Indirect im... | ['Animals', 'Basement Membrane', 'Collagen', 'DNA Probes', 'Extracellular Matrix', 'Fibronectins', 'Laminin', 'Nucleic Acid Hybridization', 'Peripheral Nerves', 'RNA, Messenger', 'Rats', 'Sciatic Nerve'] | 2,921,281 | [['B01.050'], ['A10.272.220', 'A10.615.179'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['A11.284.295.310'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['D12.776.395.550.530', 'D12.776.543.550... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of water and acetone-based dentin adhesives on apical microleakage. | In this study, the aim was to assess the in vitro apical microleakage of a resin-based sealer used with two different adhesives. Thirty nine freshly extracted maxillary incisors were used. The teeth were decoronated at the cemento-enamel junction with a water-cooled fissure bur. Chemo-mechanical debridement of the root... | ['Acetone', 'Dental Leakage', 'Dentin Permeability', 'Dentin-Bonding Agents', 'Epoxy Resins', 'Gutta-Percha', 'Humans', 'Incisor', 'Microscopy, Electron, Scanning', 'Polymethacrylic Acids', 'Resin Cements', 'Root Canal Filling Materials', 'Root Canal Obturation', 'Tooth Apex', 'Water'] | 15,150,637 | [['D02.522.064'], ['C07.793.221'], ['G10.549.845.461'], ['D25.339.291.300', 'J01.637.051.339.291.300'], ['D05.750.716.822.461', 'D25.720.716.822.461', 'J01.637.051.720.716.822.461'], ['D20.215.721.061', 'D25.339.859.495', 'D25.720.327.840.119', 'J01.637.051.339.859.495'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Murine bone marrow stromal cells sustain in vivo the survival of hematopoietic stem cells and the granulopoietic differentiation of more mature progenitors. | The study of the human hematopoietic system would be facilitated by availability of a relevant animal model. Because the medullar microenvironment is made of different types of cells, interactions between hematopoietic cells and stromal cells are difficult to analyze in detail. As an approach for establishing an in viv... | ['Adipocytes', 'Animals', 'Bone Marrow Cells', 'Cell Differentiation', 'Cell Line', 'Cell Survival', 'Cells, Cultured', 'Fibroblasts', 'Granulocytes', 'Green Fluorescent Proteins', 'Hematopoietic Stem Cell Transplantation', 'Hematopoietic Stem Cells', 'Immunohistochemistry', 'Mice', 'Stromal Cells', 'Time Factors'] | 16,293,584 | [['A11.329.114'], ['B01.050'], ['A11.148', 'A15.378.316'], ['G04.152'], ['A11.251.210'], ['G04.346'], ['A11.251'], ['A11.329.228'], ['A11.118.637.415', 'A11.148.350', 'A11.627.340', 'A15.145.229.637.415', 'A15.378.316.340', 'A15.382.490.315'], ['D12.776.532.265'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['A... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Is fixed-term employment a new risk for adverse physical working conditions? | Relationships between employment type and the physical work environment were studied among blue-collar workers (n = 1,127). Based on survey data, we set out to compare the evaluations of environmental load and physical strain at work given by fixed-term (17% of all) and permanent workers. The type of employment was not... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Employment', 'Female', 'Finland', 'Humans', 'Industry', 'Interviews as Topic', 'Job Satisfaction', 'Male', 'Middle Aged', 'Occupations', 'Personnel Staffing and Scheduling', 'Quality of Life', 'Sex Factors', 'Stress, Physiological', 'Time Factors', 'Workload', 'Workplace'... | 15,028,192 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['N01.824.245'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['F02.784.692.425'], ['M01.060.116.630... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', '... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Association Between Staphylococcus aureus Bacteremia and Hospital Mortality in Hemodialysis Patients With Bloodstream Infection: A Multicenter Cohort From Japanese Tertiary Care Centers. | Multiple studies have shown that Staphylococcus aureus bacteremia (SAB) has been a major cause of death in hemodialysis patients. We examined whether SAB is a risk for mortality among chronic hemodialysis patients in Japan where the standard vascular access is arteriovenous fistula (AVF). This was a multicenter, retros... | ['Aged', 'Aged, 80 and over', 'Arteriovenous Shunt, Surgical', 'Bacteremia', 'Female', 'Hospital Mortality', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Renal Dialysis', 'Retrospective Studies', 'Staphylococcal Infections', 'Staphylococcus aureus', 'Tertiary Care Centers'] | 28,498,647 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.035.087', 'E04.100.814.868.249'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Composition and antimicrobial activity of Equisetum arvense L. essential oil. | The volatile constituents of the sterile stems of Equisetum arvense L. (Equisetaceae) were investigated for the first time using GC, GC/MS and (13)C-NMR. Twenty-five compounds were identified. Hexahydrofarnesyl acetone (18.34%), cis-geranyl acetone (13.74%), thymol (12.09%) and trans-phytol (10.06%) were the major cons... | ['Anti-Infective Agents', 'Aspergillus niger', 'Candida albicans', 'Equisetum', 'Escherichia coli', 'Klebsiella pneumoniae', 'Microbial Sensitivity Tests', 'Oils, Volatile', 'Plant Components, Aerial', 'Plant Oils', 'Pseudomonas aeruginosa', 'Salmonella enteritidis'] | 16,397,851 | [['D27.505.954.122'], ['B01.300.381.081.450'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['B01.650.940.800.575.175'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B03.440.450.425.425.600', 'B03.660.250.150.400.590'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Institutionalizing women's oppression: the inherent risk in health policy that fosters community participation. | Current Canadian health policy is based on the implicit assumption that women are available to provide care in the home to the dependent, the ill, the elderly, and the physically and mentally disabled. Women are socialized from birth to accept caring roles within a traditional family structure, and current societal exp... | ['Canada', 'Caregivers', 'Community Participation', 'Female', 'Gender Identity', 'Health Policy', 'Health Services Needs and Demand', 'Humans', 'Socialization', "Women's Health", "Women's Rights"] | 8,407,631 | [['Z01.107.567.176'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['N02.421.143.212', 'N03.540.245.360'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.... | ['Geographicals [Z]', 'Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Folate nutriture in pregnancy. | Folacin intakes from diet and supplements consumed during pregnancy were determined by interview in 566 women. Eight percent of this population (48 women) obtained folacin from diet only. Thirteen percent (76 women) received less than two-thirds of the RDA for folacin for pregnant women. Serum and erythrocyte folate le... | ['Adult', 'Diet', 'Diet Surveys', 'Female', 'Fetal Blood', 'Folic Acid', 'Humans', 'Maternal-Fetal Exchange', 'Nutritional Requirements', 'Pregnancy'] | 3,385,101 | [['M01.060.116'], ['G07.203.650.240'], ['E05.318.308.980.485.350', 'N05.715.360.300.800.469.300', 'N06.850.505.616.300', 'N06.850.520.308.980.469.350'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['D03.633.100.733.631.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.455'], ['G07.203.650... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Angiotensin increases inositol trisphosphate and calcium in vascular smooth muscle. | Angiotensin II stimulated the breakdown of phosphatidylinositol-4,5-bisphosphate (PIP2) and the generation of inositol trisphosphate (IP3) in cultured rat aortic smooth muscle cells. The decrease in PIP2 and increase in IP3 levels were rapid (measurable at 5 seconds; maximum IP3 levels at 15 seconds). The time course o... | ['Angiotensin II', 'Animals', 'Aorta, Thoracic', 'Calcium', 'Carbon Radioisotopes', 'Cells, Cultured', 'Extracellular Space', 'Inositol 1,4,5-Trisphosphate', 'Inositol Phosphates', 'Muscle, Smooth, Vascular', 'Phosphatidylinositol 4,5-Diphosphate', 'Phosphatidylinositols', 'Rats', 'Sugar Phosphates'] | 2,987,120 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['A07.015.114.056.372'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['A11.251'], ['A10.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid determination of simazine and atrazine in water at the parts per trillion (10(12) level. Extraction by a miniaturized carbopack B trap followed by high-performance liquid chromatography. | A rapid and simple method for the determination of trace amounts of simazine and atrazine in water is described. A 250-ml volume of water is pre-concentrated by passage at a flow-rate of about 30 ml/min through a small trap containing 50 mg of graphitized carbon black (Carbopack B). After washing with 150 microliters o... | ['Atrazine', 'Chromatography, High Pressure Liquid', 'Fresh Water', 'Herbicides', 'Indicators and Reagents', 'Simazine', 'Spectrophotometry, Ultraviolet', 'Water'] | 3,693,473 | [['D03.383.931.247'], ['E05.196.181.400.300'], ['G16.500.275.280', 'N06.230.232'], ['D27.720.031.700.366', 'D27.888.723.366'], ['D27.720.470.410'], ['D03.383.931.819'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Evidence for the possible involvement of Ca2+ entry blockade in the relaxation by class I antiarrhythmic drugs in the isolated pig coronary smooth muscle. | Effects of several Na+ channel blockers (i.e., class I antiarrhythmic agents), procainamide, quinidine, lidocaine, mexiletine, propafenone, were investigated in the isolated endothelium-denuded pig coronary artery focusing on the possible involvement of the blockade of Ca2+ channels and/or opening of K+ channels in the... | ['Animals', 'Anti-Arrhythmia Agents', 'Calcium Channel Blockers', 'Calcium Channels', 'Calcium Chloride', 'Coronary Vessels', 'Cromakalim', 'Diltiazem', 'Dose-Response Relationship, Drug', 'Muscle, Smooth, Vascular', 'Potassium Chloride', 'Swine', 'Tetrodotoxin', 'Vasodilation', 'Vasodilator Agents'] | 11,862,334 | [['B01.050'], ['D27.505.954.411.097'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['D01.146.300', 'D01.210.450.150.150'], ['A07.015.114.269', 'A07.015.908.194'], ['D03.383.129.578.150', 'D03.383.663.283.455', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gram-scale solution-phase synthesis of selective sodium bicarbonate co-transport inhibitor S0859: in vitro efficacy studies in breast cancer cells. | Na(+)-coupled HCO(3)(-) transporters (NBCs) mediate the transport of bicarbonate ions across cell membranes and are thus ubiquitous regulators of intracellular pH. NBC dysregulation is associated with a range of diseases; for instance, NBCn1 is strongly up-regulated in a model of ErbB2-dependent breast cancer, a malign... | ['Animals', 'Benzamides', 'Breast Neoplasms', 'Cell Line, Tumor', 'Female', 'Humans', 'Hydrogen-Ion Concentration', 'MCF-7 Cells', 'Mice', 'Sodium-Bicarbonate Symporters', 'Sulfonamides'] | 22,927,258 | [['B01.050'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['A11.251.210.190.630'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.157.530.450.437.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Murine Pancreatic Islet Cell-based Screening for Diabetogenic Environmental Chemicals. | Exposure to certain environmental chemicals in human and animals has been found to cause cellular damage of the pancreatic â cells which will lead to the development of type 2 diabetes mellitus (T2DM). Although the mechanisms for the chemical-induced â cell damage were unclear and likely to be complex, one recurring fi... | ['Animals', 'Diabetes Mellitus, Type 2', 'Environmental Exposure', 'Environmental Pollutants', 'Humans', 'Insulin-Secreting Cells', 'Mice', 'Mice, Inbred C57BL', 'Reactive Oxygen Species', 'Xenobiotics'] | 29,985,354 | [['B01.050'], ['C18.452.394.750.149', 'C19.246.300'], ['N06.850.460.350'], ['D27.888.284'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.734.414.131', 'A06.300.414.087', 'A06.390.131', 'A11.382.625.092', 'A11.436.294.092'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.... | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Global well-posedness of infectious disease models without life-time immunity: the cases of cholera and avian influenza. | We study the systems of partial differential equations with diffusion that model the dynamics of infectious diseases without life-time immunity, in particular the cases of cholera from Wang & Wang (2015, J. Biol. Dyn., 9, 233-261) and avian influenza from Vaidya et al. (2012, Discrete Contin. Dyn. Syst. Ser. B, 17, 282... | ['Animals', 'Birds', 'Cholera', 'Communicable Diseases', 'Humans', 'Immunity', 'Influenza in Birds', 'Models, Theoretical'] | 29,088,361 | [['B01.050'], ['B01.050.150.900.248'], ['C01.150.252.400.959.347'], ['C01.221', 'C23.550.291.531'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450'], ['C01.925.782.620.300', 'C22.131.450'], ['E05.599']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Localization of insulin-like protein in the submaxillary glands of laboratory animals]. | Insulin-like protein (ILP) was extracted from the submaxillary glands of cats, guinea-pigs and male rabbits. As shown by radioimmunoassay, it is localized in the cells of the striated ducts of the salivary tubes. ILP is likely to be related to small granules visible under electron microscope. These granules are largely... | ['Animals', 'Cats', 'Guinea Pigs', 'Insulin', 'Insulin Antibodies', 'Male', 'Microscopy, Electron', 'Pancreas', 'Rabbits', 'Salivary Proteins and Peptides', 'Submandibular Gland'] | 6,996,764 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['B01.050.150.900.649.313.992.550'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D12.776.124.486.485.114.656', 'D12.776.124.790.651.114.656', 'D12.776.377.715.548.114.656'], ['E01.370.350.515.402', 'E05.595.402'], ['A03.734'], ['B01.05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Surgical management for isolated cricoid fracture causing arytenoid immobility. | Cricoid cartilage fractures usually occur concurrently with disorders of laryngeal function. In, particular, displaced cricoid lamina fractures can affect arytenoid movement. However, functional, recovery may require proper repositioning of the cricoid lamina, which is associated with a high rate of, complications. Her... | ['Arytenoid Cartilage', 'Baseball', 'Cricoid Cartilage', 'Fractures, Cartilage', 'Hoarseness', 'Humans', 'Male', 'Tomography, X-Ray Computed', 'Wounds, Nonpenetrating', 'Young Adult'] | 24,268,328 | [['A02.165.257.625.083', 'A02.165.407.500.083', 'A04.329.591.085'], ['I03.450.642.845.110'], ['A02.165.257.625.211', 'A02.165.407.500.211', 'A04.329.591.211'], ['C26.411'], ['C08.360.940.490', 'C08.618.490', 'C09.400.940.490', 'C10.597.975.550', 'C23.888.592.979.550', 'C23.888.852.490'], ['B01.050.150.900.649.313.988.4... | ['Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[Correlation analysis of clinical medication of ectopic pregnancy based on hospital information system data]. | To analyze the reality of ectopic pregnancy patients' clinical medication, find out the association rules of chemical medicine and traditional Chinese medicine, HIS data from 15 grade III-A general hospitals were collected, descriptive statistic methods and association rules were used in analysis of the data. The resul... | ['Drugs, Chinese Herbal', 'Female', 'Hospital Information Systems', 'Humans', 'Medicine, Chinese Traditional', 'Pregnancy', 'Pregnancy, Ectopic'] | 25,532,382 | [['D20.215.784.500.350', 'D26.335'], ['N04.452.442.452.452', 'N04.452.515.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['G08.686.784.769'], ['C13.703.733']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Massive autoclaved allografts and autografts for limb salvage surgery. A 1-8 year follow-up of 23 patients. | We performed 23 reconstructions with bone grafts autoclaved at 135 degrees C for 10 minutes for extensive bone defects after tumor resection. In 15 cases, the resected specimens were autoclaved and used as autografts. In 7 cases, allografts obtained from amputated extremities or cadavers were autoclaved and immediately... | ['Adolescent', 'Adult', 'Aged', 'Bone Neoplasms', 'Bone Transplantation', 'Child', 'Extremities', 'Follow-Up Studies', 'Hot Temperature', 'Humans', 'Middle Aged', 'Osseointegration', 'Sterilization', 'Time Factors', 'Tissue Preservation', 'Treatment Outcome'] | 9,310,047 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C04.588.149', 'C05.116.231'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['M01.060.406'], ['A01.378'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', '... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The kinetics of thermal degradation of polyphenolic compounds from elderberry ( Sambucus nigra L.) extract. | This main focus of this study was to evaluate the thermal degradation kinetics and the phytochemical characterization of the elderberries extract. Pelargonidin-3-sophoroside and delphinidin-3-glucoside were identified as the major anthocyanin compounds and catechin hydrate as the major flavonoid compound. In order to f... | ['Anthocyanins', 'Antioxidants', 'Food Handling', 'Glucosides', 'Hot Temperature', 'Hydrogen-Ion Concentration', 'Phytochemicals', 'Plant Extracts', 'Polyphenols', 'Sambucus'] | 29,409,346 | [['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['J01.576.423.200'], ['D09.408.348'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.72... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Characterization of O-methyltransferase ScOMT1 cloned from Streptomyces coelicolor A3(2). | The roles of O-methyltransferases (OMTs) in microorganisms are not well understood, and are suggested to increase antimicrobial activity. Studies on OMTs cloned from microorganisms may help elucidate their roles. Streptomyces coelicolor A3(2) produces many useful natural antibiotics such as actinorhodin. Based on seque... | ['Amino Acid Sequence', 'Cloning, Molecular', 'Flavones', 'Methyltransferases', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Sequence Homology, Amino Acid', 'Streptomyces coelicolor'] | 16,054,248 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.220'], ['D03.383.663.283.266.450.260', 'D03.633.100.150.266.450.260'], ['D08.811.913.555.500'], ['L01.453.245.667'], ['E05.393.620.500'], ['G02.111.810.200', 'G05.810.200'], ['B03.300.390.400.810.768.200', 'B03.510.024.997.775.200', 'B03.510.415.400.810.768.200', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Preference toward a T-helper type 1 response in patients with coronary spastic angina. | BACKGROUND: Coronary artery spasm plays an important role in the pathogenesis of ischemic heart diseases such as unstable angina (UA) and acute myocardial infarction. Nitric oxide (NO) plays an important role in coronary artery spasm. We previously reported a deficiency in NO activity in the spasm arteries of patients ... | ['Adult', 'Aged', 'Angina Pectoris', 'Angina, Unstable', 'Coronary Vasospasm', 'Female', 'Humans', 'Interferon-gamma', 'Interleukin-4', 'Male', 'Middle Aged', 'Nitric Oxide Donors', 'Th1 Cells', 'Th2 Cells'] | 12,695,292 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['C14.280.647.187.150', 'C14.907.585.187.150', 'C23.888.592.612.233.500.150'], ['C14.280.647.250.295', 'C14.907.585.250.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.893', 'D12.644.2... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Directed Supramolecular Organization of N-BAR Proteins through Regulation of H0 Membrane Immersion Depth. | Many membrane remodeling events rely on the ability of curvature-generating N-BAR membrane proteins to organize into distinctive supramolecular configurations. Experiments have revealed a conformational switch in N-BAR proteins resulting in vesicular or tubular membrane shapes, with shallow membrane immersion of the H0... | ['Biomechanical Phenomena', 'Cell Membrane', 'Elasticity', 'Hydrophobic and Hydrophilic Interactions', 'Lipid Bilayers', 'Membrane Proteins', 'Molecular Dynamics Simulation', 'Protein Conformation, alpha-Helical', 'Protein Domains'] | 30,401,832 | [['G01.154.090', 'G01.374.089'], ['A11.284.149'], ['G01.374.590'], ['G02.409'], ['D10.570.510', 'J01.637.087.500.510'], ['D12.776.543'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G02.111.570.820.709.600.020'], ['G02.111.570.820.709.275.750', 'G02.111.570.820.709.610.500']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Dental examiners consistency in applying the ICDAS criteria for a caries prevention community trial. | AIM: To examine dental examiners' one-year consistency in utilizing the International Caries Detection and Assessment System (ICDAS) criteria after baseline training and calibration.METHODS: A total of three examiners received baseline training/calibration by a "gold standard" examiner, and one year later re-calibratio... | ['Adolescent', 'Child', 'Child, Preschool', 'Clinical Trials as Topic', 'Community Dentistry', 'DMF Index', 'Dental Caries', 'Dental Caries Activity Tests', 'Dental Restoration, Permanent', 'Dentists', 'Feasibility Studies', 'Humans', 'Observer Variation', 'Reproducibility of Results'] | 21,916,361 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['H02.163.876.770.357'], ['E05.318.308.980.438.300.350', 'E06.208.266', 'N05.715.360.300.800.438.300.340', 'N06.850.520.308.980.438.300.350', 'N06.890.160.100'], ['C07.793.720.210'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
The lateral geniculate nucleus does not project to area TE in infant or adult macaques. | We sought to determine if there are any direct projections from the dorsal lateral geniculate nucleus (dLGN) to visual cortical area TE in either adult or infant primates. To do so, we examined labelling in the thalamus of eight macaque monkeys which received injections of the retrograde tracer cholera toxin-B subunit ... | ['Animals', 'Brain Mapping', 'Geniculate Bodies', 'Macaca fascicularis', 'Neural Pathways', 'Visual Cortex'] | 8,905,726 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.317.826.701.444'], ['B01.050.150.900.649.313.988.400.112.199.120.510.520'], ['A08.612'], ['A08.186.211.200.885.287.500.571.735', 'A08.186.211.200.885.287.500.814.953']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
COVID 19 and Spanish flu pandemics: All it changes, nothing changes. | The Corona Virus 19 (COVID 19) epidemic is an infectious disease which was declared as a pandemic and hit all the Countries, all over the world, from the beginning of the year 2020. There are many similarities between the COVID 19 epidemic and the Spanish flu epidemic. We considered some preventive measures which do no... | ['Betacoronavirus', 'COVID-19', 'Coronavirus Infections', 'History, 20th Century', 'Humans', 'Influenza Pandemic, 1918-1919', 'Italy', 'Pandemics', 'Pneumonia, Viral', 'SARS-CoV-2'] | 32,420,960 | [['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['C01.925.782.600.550.200'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.400.504.968.450'], ['Z01.542.4... | ['Organisms [B]', 'Diseases [C]', 'Humanities [K]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
A further prospective evaluation of an equation to predict daily lithium dose. | BACKGROUND: Recently, one prospective study confirmed the safety and accuracy of a lithium-dose prediction equation created by Zetin et al., but no definitive conclusion on the reliability of the equation has been established as yet.METHOD: The authors applied the Zetin et al. equation to 18 chronic male schizophrenic ... | ['Adult', 'Aged', 'Algorithms', 'Blood Urea Nitrogen', 'Chronic Disease', 'Creatinine', 'Drug Administration Schedule', 'Hospitalization', 'Humans', 'Kidney Function Tests', 'Lithium Carbonate', 'Male', 'Middle Aged', 'Probability', 'Prospective Studies', 'Schizophrenia'] | 7,737,958 | [['M01.060.116'], ['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['E01.370.225.124.100.115', 'E01.370.390.400.100', 'E05.200.124.100.115'], ['C23.550.291.500'], ['D03.383.129.308.207'], ['E02.319.283'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.390.400'], ['D01.045... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Overexpression of Arabidopsis thaliana brassinosteroid-related acyltransferase 1 gene induces brassinosteroid-deficient phenotypes in creeping bentgrass. | Brassinosteroids (BRs) are naturally occurring steroidal hormones that play diverse roles in various processes during plant growth and development. Thus, genetic manipulation of endogenous BR levels might offer a way of improving the agronomic traits of crops, including plant architecture and stress tolerance. In this ... | ['Arabidopsis', 'Steroids', 'Transferases'] | 29,084,267 | [['B01.650.940.800.575.912.250.157.100'], ['D04.210.500'], ['D08.811.913']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Circadian rhythm in tolerance of mice for etoposide. | Etoposide (40 mg/kg/day X 3 days and 60 mg/kg/day X 3 days) was best tolerated by male B6D2F1 mice when given in the second half of the rest span of their sleep-wake circadian cycle. Such a time-qualified treatment resulted in increased long-term survival rate, highest peripheral leukocyte count at nadir, and lowest bo... | ['Animals', 'Body Weight', 'Circadian Rhythm', 'Disease Models, Animal', 'Drug Tolerance', 'Etoposide', 'Leukocyte Count', 'Light', 'Lung Diseases', 'Male', 'Mathematics', 'Mice', 'Podophyllotoxin'] | 4,075,319 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G07.180.562.190'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.992'], ['D02.455.426.559.847.638.960.675.250', 'D04.615.638.960.675.250', 'D09.408.348.275'], ['E01.370.225... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Electronic health records as a key to objective health care needs assessment beyond the hospital boundary. | The continuous challenge within all health services--to use finite resources to the best advantage of patient care--is resulting in the need to ensure that the delivery of care most effectively meets the health needs of the population. Three models of identifying health need are outlined. The development of an integrat... | ['Community Health Services', 'Health Services Needs and Demand', 'Medical Records Systems, Computerized', 'United Kingdom'] | 8,591,174 | [['N02.421.143'], ['N03.349.380.420', 'N05.300.450'], ['E05.318.308.940.968.625', 'L01.313.500.750.300.695', 'N04.452.859.564.650', 'N05.715.360.300.715.500.530', 'N06.850.520.308.940.968.625'], ['Z01.542.363']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Population and systems genetics analyses of cortisol in pigs divergently selected for stress. | This study presents a systems genetic analysis on the physiology of cortisol in mice and pigs with an aim to show the potential of a comprehensive computational approach to quickly identify candidate genes and avoid a costly whole-genome quantitative trait locus (QTL) mapping. Population genetics analyses were performe... | ['Animals', 'Gene Expression Regulation', 'Genetics, Population', 'Hydrocortisone', 'Mice', 'Polymorphism, Single Nucleotide', 'Quantitative Trait Loci', 'Quantitative Trait, Heritable', 'Receptors, Corticotropin-Releasing Hormone', 'Selection, Genetic', 'Stress, Physiological', 'Sus scrofa'] | 17,132,818 | [['B01.050'], ['G05.308'], ['H01.158.273.343.335'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['B01.050.150.900.649.313.992.635.505.500'], ['G05.365.795.598'], ['G05.360.340.024.380.937'], ['G05.420.720'], ['D12.776.543.750.695.180', 'D12.776.543.750.720.600.290', 'D12.776.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Polycyclic polyprenylated acylphloroglucinols and chromone O-glucosides from Hypericum henryi subsp. uraloides. | Two new C(30)-epimeric polycyclic polyprenylated acylphloroglucinols (PPAPs), named uralodins B and C (1 and 2, resp.), were isolated from the aerial parts of Hypericum henryi subsp. uraloides together with two new chromone glucosides, urachromones A and B (3 and 4, resp.), as well as 16 known compounds. Their structur... | ['Cell Line, Tumor', 'Chromones', 'Drug Screening Assays, Antitumor', 'Glucosides', 'HL-60 Cells', 'Hep G2 Cells', 'Humans', 'Hypericum', 'K562 Cells', 'Molecular Conformation', 'Phloroglucinol'] | 20,087,990 | [['A11.251.210.190', 'A11.251.860.180'], ['D03.383.663.283.266', 'D03.633.100.150.266'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['D09.408.348'], ['A11.251.210.190.465', 'A11.251.860.180.465', 'A11.627.340.360.500'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thermal decomposition of ammonium perchlorate in the presence of Al(OH)(3)·Cr(OH)(3) nanoparticles. | An Al(OH)(3)·Cr(OH)(3) nanoparticle preparation procedure and its catalytic effect and mechanism on thermal decomposition of ammonium perchlorate (AP) were investigated using transmission electron microscopy (TEM), X-ray diffraction (XRD), thermogravimetric analysis and differential scanning calorimetry (TG-DSC), X-ray... | ['Aluminum Hydroxide', 'Calorimetry, Differential Scanning', 'Catalysis', 'Chemical Precipitation', 'Chromium Compounds', 'Crystallization', 'Fires', 'Hot Temperature', 'Microscopy, Electron, Transmission', 'Nanoparticles', 'Perchlorates', 'Photoelectron Spectroscopy', 'Quaternary Ammonium Compounds', 'Surface Properti... | 24,530,852 | [['D01.045.250.050', 'D01.056.037', 'D01.248.497.158.459.075'], ['E05.196.131.310', 'E05.196.370.310'], ['G02.130'], ['E05.196.150', 'G02.159'], ['D01.220'], ['E05.196.300', 'G02.171'], ['N06.230.216'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Mycophenolic acid pharmacokinetics in stable pediatric renal transplantation. | Mycophenolate mofetil (MMF) is given to children in fixed doses based either on body weight or body surface area. There are data indicating mycophenolic acid (MPA) blood levels should be monitored in the early period of transplantation. However, there is little information regarding MPA pharmacokinetics (PK) in stable ... | ['Adolescent', 'Area Under Curve', 'Child', 'Drug Monitoring', 'Female', 'Humans', 'Immunosuppressive Agents', 'Kidney Transplantation', 'Linear Models', 'Male', 'Mycophenolic Acid'] | 12,644,921 | [['M01.060.057'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['M01.060.406'], ['E01.370.520.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Contemporary organization and necessary scope of community social psychiatric service (exemplified by North Rhine Westphalia)]. | A model programme on psychiatric care had been carried out and evaluated in the Federal Republic of Germany in 1985 (the year of its completion) and was based on the (then assumed) existence of public sociopsychiatric services as one of the (meanwhile self-understood) corner-stones of communal care for psychiatric pati... | ['Community Mental Health Services', 'Forecasting', 'Germany, West', 'Health Services Needs and Demand', 'Health Services Research', 'Humans', 'Mental Disorders', 'Referral and Consultation', 'Social Work, Psychiatric'] | 2,528,094 | [['F04.408.307', 'N02.421.143.183', 'N02.421.461.232'], ['I01.320'], ['Z01.586.350'], ['N03.349.380.420', 'N05.300.450'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['N04.452.758.849'], ['F04.408.823', 'I01.880.792.410', 'N02.421.461.798', 'N02.421.849.6... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Dural metastasis at medulla oblongata: a rare cause of vocal fold paralysis. | Malignancy is a major cause of vocal fold paralysis. Nevertheless, metastatic disease at the brainstem leading to high vagal paralysis is rarely encountered. We illustrate an unusual case of unilateral vocal fold paralysis caused by dural metastasis directly compressing on the nucleus ambiguus. The median position of t... | ['Brain Neoplasms', 'Brain Stem', 'Dura Mater', 'Female', 'Humans', 'Lung Neoplasms', 'Magnetic Resonance Imaging', 'Middle Aged', 'Vocal Cord Paralysis'] | 8,949,305 | [['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['A08.186.211.132'], ['A08.186.566.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C08.360.931', 'C09.400.931', 'C10.292.887.800', 'C10.597.622.9... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A long-term follow-up analysis in adult acute myeloid leukemia patients after hematopoietic stem cell transplantation. | AIMS AND BACKGROUND: Over the last 17 years, 119 adult acute myeloid leukemia patients have undergone hematopoietic stem cell transplantation at our Center.STUDY DESIGN: Seventy patients in first complete remission received hematopoietic stem cell transplantation (28 allogeneic and 42 autologous HSCT) as late intensifi... | ['Adolescent', 'Adult', 'Aged', 'Antineoplastic Agents', 'Chemotherapy, Adjuvant', 'Child', 'Cytarabine', 'Disease-Free Survival', 'Female', 'Follow-Up Studies', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Leukemia, Myeloid, Acute', 'Life Tables', 'Male', 'Middle Aged', 'Remission Induction', 'Survival Analys... | 16,459,634 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['E02.186.170', 'E02.319.170'], ['M01.060.406'], ['D03.383.742.680.245.453', 'D13.570.065.300', 'D13.570.685.245.453'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fibronectin in artery subendothelium is important for platelet adhesion. | The role of subendothelial fibronectin in platelet interaction with subendothelium was studied. Human umbilical artery subendothelium was exposed to flowing blood containing 111In-labeled platelets in an annular perfusion chamber. Platelet adhesion was determined from the 111In radioactivity on the vessel wall. When pe... | ['Animals', 'Antibodies', 'Endothelium', 'Fibronectins', 'Fluorescent Antibody Technique', 'Humans', 'Immunoglobulin Fab Fragments', 'Platelet Adhesiveness', 'Rabbits', 'Umbilical Arteries'] | 3,882,170 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['A10.272.491'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Free Will, Determinism, and Intuitive Judgments About the Heritability of Behavior. | The fact that genes and environment contribute differentially to variation in human behaviors, traits and attitudes is central to the field of behavior genetics. Perceptions about these differential contributions may affect ideas about human agency. We surveyed two independent samples (N = 301 and N = 740) to assess be... | ['Adolescent', 'Adult', 'Aged', 'Attitude', 'Behavior', 'Culture', 'Female', 'Genetic Determinism', 'Humans', 'Inheritance Patterns', 'Intuition', 'Judgment', 'Male', 'Middle Aged', 'Personal Autonomy', 'Quantitative Trait, Heritable', 'Young Adult'] | 30,315,376 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F01.100'], ['F01.145'], ['I01.076.201.450', 'I01.880.853.100'], ['F04.096.276.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.420'], ['F02.463.188.675'], ['F02.463.785.626'], ['M01.060.116.630'], ['F02.600', 'I01.880.604.473.380.500', 'K01.752.566.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Microbial fuel cells for direct electrical energy recovery from urban wastewaters. | Application of microbial fuel cells (MFCs) to wastewater treatment for direct recovery of electric energy appears to provide a potentially attractive alternative to traditional treatment processes, in an optic of costs reduction, and tapping of sustainable energy sources that characterizes current trends in technology.... | ['Bioelectric Energy Sources', 'Electrochemical Techniques', 'Urban Renewal', 'Waste Water', 'Water Purification'] | 24,453,885 | [['E07.305.124.150'], ['E05.301'], ['I01.880.709.876'], ['D20.944.932', 'N06.850.460.710.865'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Fine needle aspiration of palpable breast lumps: a 1-year audit using the Cytospin method. | A fine-needle aspiration (FNA) service for the diagnosis of palpable breast lumps was started at the Royal Preston Hospital, Preston, UK, in November 1989. Over the subsequent year, 407 FNAs were taken from 393 women. A simple technique was used which involved the surgeon flushing the aspirate into 10 ml of Cytospin co... | ['Biopsy, Needle', 'Breast Neoplasms', 'Female', 'Humans', 'Sensitivity and Specificity'] | 1,562,710 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Kinetic analysis of synthetic analogues of linear-epitope peptides of glycoprotein D of herpes simplex virus type 1 by surface plasmon resonance. | The interaction between mAb A16 and glycoprotein D (gD) of herpes simplex virus type 1 was analyzed by studying the kinetics of binding with a surface-plasmon-resonance biosensor. mAb A16 belongs to group VII antibodies, which recognize residues 11-19 of gD. In a previous study, three critical residues, Asp13, Arg16 an... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Antigen-Antibody Complex', 'Cell Line', 'Cloning, Molecular', 'Epitopes', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Mutagenesis, Site-Directed', 'Peptide Fragments', 'Recombinant Proteins', 'Simplexvirus', 'Spodoptera', 'Transfection', 'Viral Envelope ... | 8,797,855 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['A11.251.210'], ['E05.393.220'], ['D23.050.550'], ['G01.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Heterologous priming-boosting with DNA and vaccinia virus expressing kinetoplastid membrane protein-11 induces potent cellular immune response and confers protection against infection with antimony resistant and sensitive strains of Leishmania (Leishmania) donovani. | BACKGROUND: Emergence of resistance against commonly available drugs poses a major threat in the treatment of visceral leishmaniasis (VL), particularly in the Indian subcontinent. Absence of any licensed vaccine against VL emphasizes the urgent need to develop an effective alternative vaccination strategy.METHODOLOGY: ... | ['Animals', 'Antimony', 'Cricetinae', 'Cross-Priming', 'Cytokines', 'Drug Resistance', 'Female', 'Immunity, Cellular', 'Immunity, Humoral', 'Leishmania donovani', 'Leishmaniasis, Visceral', 'Membrane Glycoproteins', 'Mice', 'Mice, Inbred BALB C', 'Protozoan Proteins', 'Protozoan Vaccines', 'T-Lymphocytes', 'Vaccination... | 23,499,564 | [['B01.050'], ['D01.268.513.124', 'D01.268.556.050', 'D01.552.544.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['G12.450.050.400.545.150', 'G12.565.150'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.690.773.984'], ['G12.450.050.400'], ['G12.450.050.420'], ['B01.268.475.868.488.230'], ['C01.610.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[The use of adalimumab in severe fistulising Crohn's disease]. | So far infliximab is the only approved anti-TNF-alpha antibody for patients with Crohn's disease. Development of antibodies to infliximab may result in allergic reactions or reduced effect. We report three patients who received adalimumab, which induced longstanding remission in all three patients. | ['Adalimumab', 'Adult', 'Anti-Inflammatory Agents', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Humanized', 'Crohn Disease', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Rectal Fistula', 'Treatment Outcome'] | 18,565,318 | [['D12.776.124.486.485.114.224.060.250', 'D12.776.124.790.651.114.224.060.250', 'D12.776.377.715.548.114.224.200.250'], ['M01.060.116'], ['D27.505.954.158'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.06... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of breast tumour cell contamination in the bone marrow and leukapheresis collections by RT-PCR for cytokeratin-19 mRNA. | There is considerable interest in an autologous transplantation (AT) programme for patients with high-risk breast cancer; however, the issue of the incidence of occult bone marrow (BM) micrometastasis at diagnosis, and the cancer contamination of peripheral blood stem cell (PBSC) collections used for haematological res... | ['Adult', 'Antigens, CD34', 'Bone Marrow Neoplasms', 'Breast Neoplasms', 'Disease-Free Survival', 'Female', 'Granulocyte Colony-Stimulating Factor', 'Hematopoietic Stem Cell Mobilization', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Immunohistochemistry', 'Keratins', 'Leukapheresis', 'Middle Aged', 'RNA, Mess... | 9,858,208 | [['M01.060.116'], ['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['C04.588.448.200', 'C15.378.190.250', 'C15.378.400.200'], ['C04.588.180', 'C17.800.090.500'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
First characterization of extremely halophilic 2-deoxy-D-ribose-5-phosphate aldolase. | 2-Deoxy-d-ribose-5-phosphate aldolase (DERA) catalyzes the aldol reaction between two aldehydes and is thought to be a potential biocatalyst for the production of a variety of stereo-specific materials. A gene encoding DERA from the extreme halophilic archaeon, Haloarcula japonica, was overexpressed in Escherichia coli... | ['Aldehyde-Lyases', 'Archaeal Proteins', 'Enzyme Stability', 'Escherichia coli', 'Haloarcula', 'Recombinant Proteins', 'Sodium Chloride'] | 27,215,670 | [['D08.811.520.224.062'], ['D12.776.090'], ['E05.916.360', 'G02.111.700.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B02.200.400.400.400'], ['D12.776.828'], ['D01.210.450.150.875', 'D01.857.650']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Low-Molecular-Weight Heparin-Coated and Montelukast-Filled Inhalable Particles: A Dual-Drug Delivery System for Combination Therapy in Asthma. | Montelukast, a cysteinyl leukotriene type 1 receptor antagonist, exhibits secondary anti-inflammatory properties when used at higher concentrations. Low-molecular-weight heparin (LMWH) evokes pronounced anti-inflammatory effects by interrupting leukocyte adhesion and migration. We hypothesized that inhalable particles ... | ['Acetates', 'Administration, Inhalation', 'Animals', 'Anti-Asthmatic Agents', 'Anticoagulants', 'Asthma', 'Dose-Response Relationship, Drug', 'Drug Delivery Systems', 'Drug Therapy, Combination', 'Heparin, Low-Molecular-Weight', 'Inflammation Mediators', 'Male', 'Microspheres', 'Particle Size', 'Polyesters', 'Polyethy... | 28,057,540 | [['D02.241.081.018', 'D10.251.400.045'], ['E02.319.267.050'], ['B01.050'], ['D27.505.954.796.050'], ['D27.505.954.502.119'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.300'], ['E02.319.310'], ['D09.698.373.400.300'], ['D23.469'], ['E07.565... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Allelic frequency determination of the 24-bp chitotriosidase duplication in the Portuguese population by real-time PCR. | Chitotriosidase is a human chitinase produced by macrophages. Its enzymatic activity is markedly elevated in serum of patients suffering from lysosomal storage disorders, as well as other diseases in which macrophages are activated. Therefore, it is a useful tool as a secondary marker in the diagnosis of several disord... | ['Base Sequence', 'Biomarkers', 'Female', 'Gaucher Disease', 'Gene Frequency', 'Hexosaminidases', 'Humans', 'Male', 'Mutation', 'Niemann-Pick Diseases', 'Polymerase Chain Reaction', 'Portugal'] | 15,528,158 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D23.101'], ['C10.228.140.163.100.435.825.400', 'C16.320.565.189.435.825.400', 'C16.320.565.398.641.803.441', 'C16.320.565.595.554.825.400', 'C18.452.132.100.435.825.400', 'C18.452.584.687.803.441', 'C18.452.648.189.435.825.400', 'C18.452.648.398.641.803.441'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Profiling transcriptomic response of Enchytraeus albidus to Cu and Ni: comparison with Cd and Zn. | Metals are among the most common contaminants in soils in Europe. Although their effects are relatively well known regarding survival and reproduction to soil invertebrates, their mode of action is poorly understood. Enchytraeus albidus is a model organism in ecotoxicology and with the development of a gene library for... | ['Animals', 'Cadmium', 'Cluster Analysis', 'Copper', 'Ecotoxicology', 'Europe', 'Metals', 'Nickel', 'Oligochaeta', 'Soil', 'Soil Pollutants', 'Zinc'] | 24,361,568 | [['B01.050'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['H01.158.273.248.500', 'H01.158.891.211', 'H01.277.249.500', 'H02.884.211'], ['Z01.542'], ['D01.552'], ['D01.268.556.607... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Economic evaluation of specific immunotherapy versus symptomatic treatment of allergic rhinitis in Germany. | OBJECTIVE: To use published data to compare the economic consequences of specific immunotherapy (SIT) lasting 3 years with those of continuous symptomatic treatment in patients with either pollen or mite allergy.DESIGN AND SETTING: The evaluation was conducted from the following 3 perspectives in Germany: (i) society; ... | ['Delivery of Health Care', 'Economics, Pharmaceutical', 'Follow-Up Studies', 'Germany', 'Humans', 'Immunotherapy', 'Insurance, Health', 'Mite Infestations', 'Pollen', 'Prevalence', 'Rhinitis, Allergic, Perennial'] | 10,747,764 | [['N04.590.374', 'N05.300'], ['N03.219.390'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425'], ['N03.219.521.576.343'], ['C01.610.858.211.480'], ['A18.024.249.500.249.500'], ['E05.318.308.985... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Exogenous Pseudomonas endophthalmitis: a cause of lens enucleation. | Pseudomonas aeruginosa eye infection, although uncommon, may be a devastating disease if not recognised and treated appropriately, especially in premature infants. The case is presented of a premature baby who lost her right eye from invasive exogenous Ps aeruginosa eye infection. | ['Endophthalmitis', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Lens Diseases', 'Male', 'Pseudomonas Infections', 'Pseudomonas aeruginosa'] | 11,978,756 | [['C01.375.265', 'C11.294.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['C11.510'], ['C01.150.252.400.739'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Modified fluid wax impression for a severely resorbed edentulous mandibular ridge. | This article describes a technique for making a definitive impression for highly displaceable residual ridges. The technique is especially applicable for mandibular edentulous ridges. The choice of the impression materials, as well as the design of the impression tray, focuses on preventing distortion of the displaceab... | ['Alveolar Bone Loss', 'Dental Impression Materials', 'Dental Impression Technique', 'Dental Models', 'Denture Design', 'Humans', 'Jaw, Edentulous', 'Mandible', 'Polyvinyls', 'Siloxanes', 'Waxes'] | 19,328,281 | [['C05.116.264.150', 'C07.465.714.354.500'], ['D25.339.334', 'J01.637.051.339.334'], ['E06.912.130'], ['E06.261', 'J01.897.280.500.545.129.200', 'L01.178.820.090.545.129.200'], ['E06.780.346.760.300', 'E06.912.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.500.480', 'C07.320.550', 'C07.465.550.425', 'C07... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
[Calification of the dental system in dialized patients]. | The authors present the case of an eight-years-old child, dialysed since the age of two following a bilateral nephrectomy. The chronological appearance of the teeth was not disturbed. By contrast, there was a delay in mineralisation of the dental organ, and in particular the root. There was lysis of the alveolar bone, ... | ['Acute Kidney Injury', 'Alveolar Process', 'Bone Resorption', 'Child', 'Female', 'Humans', 'Odontodysplasia', 'Renal Dialysis', 'Tooth Calcification'] | 206,956 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['C05.116.264', 'G11.427.213.150'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.650.800.600', 'C07.793.700.600', 'C16.131.850.800.600'], ['E02.870.300', 'E02.912.800'],... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
G-protein stimulation inhibits amiloride-sensitive Na/H exchange independently of cyclic AMP. | G-proteins are heterotrimeric proteins involved in many transmembrane signaling events. Both the renal basolateral membrane and the renal brush border membrane contain large quantities of these proteins. G-proteins appear related to hormonal signaling in the basolateral membrane and presumably affect ion gating in the ... | ['Adenylyl Cyclases', 'Amiloride', 'Animals', 'Biological Transport, Active', 'Carrier Proteins', 'Colforsin', 'Cyclic AMP', 'Female', 'GTP-Binding Proteins', 'Glucose', 'Guanine Nucleotides', 'In Vitro Techniques', 'Kidney', 'Microvilli', 'Protein Kinases', 'Rats', 'Rats, Inbred Strains', 'Signal Transduction', 'Sodiu... | 1,321,927 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['D03.383.679.149'], ['B01.050'], ['G03.143.310'], ['D12.776.157'], ['D02.455.849.291.300'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['D09.947.875.359... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Constitutive and enhanced expression from the CMV major IE promoter in a defective adenovirus vector. | A defective adenovirus (Ad) type 5 E1- vector has been combined with the powerful constitutive cytomegalovirus (CMV) major immediate early (IE) promoter to produce a novel eukaryotic expression system. The Ad vector can replicate to high titres in 293 cells and then be used to infect a wide variety of non-permissive ce... | ['Adenoviridae', 'Antigens, Viral', 'Cell Line', 'Cloning, Molecular', 'Cytomegalovirus', 'Defective Viruses', 'Gene Expression Regulation, Viral', 'Genetic Vectors', 'Humans', 'Immediate-Early Proteins', 'Kinetics', 'Promoter Regions, Genetic', 'Recombinant Proteins'] | 1,317,548 | [['B04.280.030'], ['D23.050.327'], ['A11.251.210'], ['E05.393.220'], ['B04.280.382.150.150'], ['B04.265'], ['G05.308.385'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.460', 'D12.776.964.925.968'], ['G01.374.661', 'G02.111.490'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.36... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Absence of Inferior Vena Cava in a Renal Transplant Recipient: A Case Report. | A 27-year-old woman was admitted to our department with end-stage renal failure due to reflux nephropathy. She had no history of deep venous thrombosis. After pretransplantation evaluation, her father was accepted for kidney donation. We observed intraoperatively that the patient's iliac veins and inferior vena cava (I... | ['Adult', 'Female', 'Humans', 'Iliac Vein', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Portal System', 'Radiography', 'Vena Cava, Inferior'] | 26,093,758 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.908.427'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['A07.015.908.670'], ['E01.370.350.700'], ['A07.015.908.949.648']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Building a schematic model: a blueprint for DNP students. | Doctor of nursing practice students are frequently required to design schematic models to support the theoretical underpinnings of their scholarly projects. However, there is little information in the literature that provides guidance on how to develop a schematic model. The author presents methods and practical sugges... | ['Education, Nursing, Graduate', 'Humans', 'Models, Nursing', 'Nursing Education Research', 'Nursing Methodology Research', 'Nursing Theory'] | 22,024,678 | [['I02.358.337.450', 'I02.358.462.565'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.645'], ['H01.770.644.145.390.413', 'H02.478.395.413', 'I02.358.462.612', 'N04.590.233.508.613.413'], ['H01.770.644.145.390.634', 'H02.478.395.634', 'N04.590.233.508.613.634'], ['H02.478.408']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Effect of botulinum toxin type A on nasal symptoms in patients with allergic rhinitis: a double-blind, placebo-controlled clinical trial. | OBJECTIVE: To investigate the possible beneficial effects of botulinum toxin type A (BTX-A) on nasal symptoms in patients with allergic rhinitis (AR).MATERIAL AND METHODS: Thirty-four patients (21 females, 13 males; mean age 28 years) were included in the study. AR was diagnosed by means of history, clinical examinatio... | ['Administration, Intranasal', 'Adolescent', 'Adult', 'Botulinum Toxins, Type A', 'Double-Blind Method', 'Female', 'Humans', 'Male', 'Neuromuscular Agents', 'Rhinitis, Allergic, Perennial', 'Rhinitis, Allergic, Seasonal', 'Treatment Outcome'] | 14,710,908 | [['E02.319.267.120.655.500'], ['M01.060.057'], ['M01.060.116'], ['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Quality and Structure of Outpatient Care for Adults with ADHD (Attention Deficit Hyperactivity Disorder) - Results of the RAABE-Study [Retrospective Data Analysis of ADHD Treatment in Adults]]. | OBJECTIVE: Data on the quality and structure of outpatient care for adults with ADHD in Germany are scarce. The study describes the reality of care and identifies possible measures for improvement.METHOD: A complete survey of adults ? 18 years of age with a diagnosis of ADHD (ICD-Code F90.0) covered by statutory health... | ['Adult', 'Ambulatory Care', 'Attention Deficit Disorder with Hyperactivity', 'Data Analysis', 'Germany', 'Humans', 'Quality of Health Care', 'Retrospective Studies'] | 31,408,892 | [['M01.060.116'], ['E02.760.106', 'N02.421.585.106'], ['F03.625.094.150'], ['H01.548.338'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761', 'N05.715'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Characteristics of effective interventions supporting quality pain management in Australian emergency departments: an exploratory study. | BACKGROUND: It is well established that pain is the most common presenting complaint in Emergency Departments. Despite great improvements in available pain management strategies, patients are left waiting for longer than 60min for pain relief on arrival to the emergency department. The aim of this study was to describe... | ['Analgesia', 'Analgesics', 'Australia', 'Disease Management', 'Emergency Service, Hospital', 'Humans', 'Pain', 'Pain Management', 'Pain Measurement', 'Practice Guidelines as Topic', 'Quality Assurance, Health Care', 'Treatment Outcome'] | 22,813,620 | [['E03.091'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['Z01.639.100', 'Z01.678.100.373'], ['N04.590.607'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E02.745', 'N04.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Feasibility of a biomechatronic EPP Upper Limb Prosthesis Controller. | In this paper, we examine the feasibility of an implantable topology of a Biomechatronic Extended Physiological Proprioception (EPP) Upper Limb Prosthesis Controller. Initial findings support the hypothesis that the topology is safe and feasible. This novel controller topology can maintain the advantages of EPP, but wi... | ['Artificial Limbs', 'Biomechanical Phenomena', 'Feasibility Studies', 'Hand', 'Humans', 'Proprioception', 'Temperature', 'Wireless Technology'] | 26,736,790 | [['E07.695.050', 'E07.858.082.050', 'E07.858.442.050'], ['G01.154.090', 'G01.374.089'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.830.816.541', 'G07.888.750', 'G11.561.790.541'], ['G01.906.595', 'G16.500.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Career and family aspirations of female athletic trainers employed in the National Collegiate Athletic Association Division I setting. | CONTEXT: Female athletic trainers (ATs) tend to depart the profession of athletic training after the age of 30. Factors influencing departure are theoretical. Professional demands, particularly at the collegiate level, have also been at the forefront of anecdotal discussion on departure factors.OBJECTIVE: To understand... | ['Adult', 'Career Choice', 'Data Collection', 'Employment', 'Female', 'Humans', 'Maternal Behavior', 'Middle Aged', 'Motivation', 'Parenting', 'Qualitative Research', 'Social Behavior', 'Sports', 'Surveys and Questionnaires', 'Work'] | 25,329,349 | [['M01.060.116'], ['F02.463.785.373.346.400'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N01.824.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.370.215'], ['M01.060.116.630'], ['F01.658', 'F01.752.543.500.750'], ['F01.829.263.370.310'], ['H01.770.644.241.850'], ['F01... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
A study of the correlation between cyclophilin binding and in vitro immunosuppressive activity of cyclosporine A and analogues. | In order to establish whether CyP is the pharmacologically relevant CsA receptor, the CyP binding v immunosuppressive activity was measured for an extensive, structurally varied group of CsA analogues. Overall, CyP binding was found to parallel immunosuppressive activity. Other than MeAla6-CsA, the few exceptions to th... | ['Animals', 'Carrier Proteins', 'Cyclosporins', 'Ethers', 'Immunosuppression', 'Immunosuppressive Agents', 'In Vitro Techniques', 'Interleukin-2', 'Ionomycin', 'Lymphocyte Activation', 'Lymphocyte Culture Test, Mixed', 'Mice', 'Peptidylprolyl Isomerase', 'Structure-Activity Relationship', 'Tetradecanoylphorbol Acetate'... | 2,966,482 | [['B01.050'], ['D12.776.157'], ['D04.345.566.235', 'D12.644.641.235'], ['D02.355'], ['E02.095.465.425.450', 'E05.478.610'], ['D27.505.696.477.656'], ['E05.481'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.480.372', 'D23.529.374.465.155', 'D23.529.374.480.372'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis. | A genetic variant in PNPLA3 (PNPLA3(I148M)), a triacylglycerol (TAG) hydrolase, is a major risk factor for nonalcoholic fatty liver disease (NAFLD); however, the mechanism underlying this association is not known. To develop an animal model of PNPLA3-induced fatty liver disease, we generated transgenic mice that overex... | ['Adipose Tissue', 'Amino Acid Substitution', 'Animals', 'Fatty Acids', 'Fatty Liver', 'Humans', 'Lipid Metabolism', 'Liver', 'Mice', 'Mice, Transgenic', 'Mutation, Missense', 'Non-alcoholic Fatty Liver Disease', 'Phospholipases A2, Calcium-Independent', 'Triglycerides'] | 23,023,705 | [['A10.165.114'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['D10.251'], ['C06.552.241'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.458'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['G05.365.590.650'], ['C06.... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diarrhea and respiratory symptoms among travelers to Asia, Africa, and South and Central America from Scotland. | Surveillance using admissions to hospital, while being useful, is a poor indicator of the real incidence of disease encountered by travelers. An alternative is self-reported illness among those who attended at a pretravel clinic prior to their travels. Estimates of incidence and risk factors were determined for attende... | ['Adolescent', 'Adult', 'Africa', 'Age Factors', 'Asia', 'Central America', 'Child', 'Child, Preschool', 'Diarrhea', 'Female', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged', 'Respiratory Tract Diseases', 'Risk Factors', 'Scotland', 'South America', 'Surveys and Questionnaires', 'Travel'] | 16,884,402 | [['M01.060.057'], ['M01.060.116'], ['Z01.058'], ['N05.715.350.075', 'N06.850.490.250'], ['Z01.252'], ['Z01.107.169'], ['M01.060.406'], ['M01.060.406.448'], ['C23.888.821.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Field work, narrative and knowledge production in contemporary ethnographic research: a contribution to the field of health]. | In this article I reflect on the peculiarities of contemporary ethnographic research, highlighting some challenges inherent to this process. The discussion focuses in particular on the following aspects: the limits imposed by the clear reduction in immersion time in the field; the challenges in learning about ethnograp... | ['Anthropology, Cultural', 'Humans', 'Public Health', 'Research'] | 22,450,403 | [['I01.076.201'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['H01.770.644']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Production and fungitoxic activity of Sch 642305, a secondary metabolite of Penicillium canescens. | Production of fungitoxic extrolites was evaluated in culture filtrates of several isolates belonging to Penicillium canescens and P. janczewskii that showed some extent of inhibitory activity against the plant pathogenic fungus Rhizoctonia solani. In addition to griseofulvin and dechlorogriseofulvin that are already kn... | ['Antifungal Agents', 'Chromatography, Thin Layer', 'Macrolides', 'Magnetic Resonance Spectroscopy', 'Microbial Sensitivity Tests', 'Molecular Structure', 'Penicillium', 'Plant Diseases', 'Rhizoctonia', 'Soil Microbiology'] | 17,429,757 | [['D27.505.954.122.136'], ['E05.196.181.400.537'], ['D02.540.505', 'D02.540.576.500', 'D04.345.674.500'], ['E05.196.867.519'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G02.111.570', 'G02.466'], ['B01.300.381.662'], ['G15.610'], ['B01.300.381.740'], ['H01.158.273.540.274.555', 'N06.850.425.300']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes. | We sought to explore the relationship between receptor tyrosine kinase (RTK) activated signaling pathways and the transcriptional induction of immediate early genes (IEGs). Using global expression monitoring, we identified 66 fibroblast IEGs induced by platelet-derived growth factor beta receptor (PDGFRbeta) signaling.... | ['3T3 Cells', 'Animals', 'Cell Line, Transformed', 'Fibroblasts', 'Gene Expression Regulation', 'Genes, Immediate-Early', 'Genes, Overlapping', 'Humans', 'Interferon-gamma', 'Mice', 'Mutagenesis', 'Phenylalanine', 'Receptor Protein-Tyrosine Kinases', 'Receptor, Fibroblast Growth Factor, Type 1', 'Receptor, Macrophage C... | 10,380,925 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['A11.251.210.172'], ['A11.329.228'], ['G05.308'], ['G05.360.340.024.340.330', 'G05.360.340.024.340.364.875.345', 'G05.360.340.358.024.875.345', 'G05.360.340.358.840.500.345'], ['G05.360.340.024.340.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.2... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lactose intolerance revealed by severe resistance to treatment with levothyroxine. | The most common cause of apparent ineffectiveness or resistance to treatment with oral levothyroxine (LT(4)) is the result of noncompliance, known as pseudomalabsorption. However, an abnormality in the bioavailability of LT(4) should also be considered in patients requiring large doses of LT(4) to achieve euthyroidism.... | ['Drug Resistance', 'Female', 'Humans', 'Hypothyroidism', 'Intestinal Absorption', 'Lactose Intolerance', 'Middle Aged', 'Thyroxine'] | 17,123,345 | [['G07.690.773.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.482'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.374.500', 'G10.261.353.500'], ['C06.405.469.637.506', 'C16.320.565.202.589', 'C18.452.603.506', 'C18.452.648.202.589'], ['M01.060.116.630... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Synthesis of conjugated polyrotaxanes. | A series of conjugated polyrotaxane insulated molecular wires are synthesised by aqueous Suzuki polymerisation, using hydrophobic binding to promote threading of the cyclodextrin units. These polyrotaxanes have conjugated polymer cores based on poly(para-phenylene), polyfluorene, and poly(diphenylene-vinylene), threade... | ['Cyclodextrins', 'Fluorenes', 'Light', 'Luminescent Measurements', 'Macromolecular Substances', 'Models, Molecular', 'Molecular Structure', 'Molecular Weight', 'Nanotechnology', 'Polycyclic Aromatic Hydrocarbons', 'Polyvinyls', 'Rotaxanes', 'Spectrometry, Fluorescence', 'Spectrophotometry'] | 14,679,528 | [['D04.345.103', 'D09.301.915.400.375', 'D09.698.365.855.400.375'], ['D02.455.426.559.847.389', 'D04.615.389'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E05.196.712.516'], ['D05'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['G02.494'], ['H01.603', 'J01.897.520.600'], ['D02.455.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Reinfection with hepatitis C virus following sustained virological response in injection drug users. | BACKGROUND AND AIM: Despite that 60-90% of injection drug users (IDUs) are infected with hepatitis C virus (HCV) infection, IDUs are often denied therapy based on concerns of reinfection following treatment. However, there are little data in this regard. We evaluated HCV re-infection following sustained virologic respo... | ['Adult', 'Antiviral Agents', 'British Columbia', 'Community Health Centers', 'Drug Therapy, Combination', 'Drug Users', 'Female', 'Hepacivirus', 'Hepatitis C', 'Humans', 'Interferon alpha-2', 'Interferon-alpha', 'Male', 'Middle Aged', 'Polyethylene Glycols', 'Prospective Studies', 'RNA, Viral', 'Recombinant Proteins',... | 20,594,256 | [['M01.060.116'], ['D27.505.954.122.388'], ['Z01.107.567.176.160'], ['N02.278.035.128'], ['E02.319.310'], ['M01.169'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
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