Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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An anatomic study of structure and innervation of the serratus anterior muscle. | BACKGROUND: The structure and function of the serratus anterior muscle are partitioned into three parts. If the morphological characteristics in each part can be demonstrated in more detail, the cause of dysfunction will probably be identifiable more accurately. The purpose of this study was to demonstrate the details ... | ['Cadaver', 'Female', 'Humans', 'Male', 'Muscle, Skeletal', 'Ribs', 'Scapula', 'Thoracic Nerves', 'Thoracic Wall'] | 22,638,721 | [['C23.550.260.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.567', 'A10.690.552.500'], ['A02.835.232.570.500'], ['A02.835.232.087.783'], ['A08.800.800.720.800'], ['A01.923.761.850']] | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The success of opening single chronic total occlusion lesions to improve myocardialviabilitytrial (SOS-COMEDY): Study protocol of a prospective multicenter study. | AIMS: Success of opening single (SOS)-comedy is a prospective multicenter study to compare the improvement in the decrease of myocardial viability by percutaneous coronary intervention (PCI) with that by optimal medical therapy (OMT) alone in patients with chronic total occlusion (CTO) of a single coronary artery.METHO... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anticholesteremic Agents', 'Antihypertensive Agents', 'Coronary Occlusion', 'Decision Support Techniques', 'Diet, Reducing', 'Humans', 'Middle Aged', 'Percutaneous Coronary Intervention', 'Platelet Aggregation Inhibitors', 'Positron Emission Tomography Computed Tomo... | 29,668,609 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['D27.505.954.411.162'], ['C14.280.647.250.272', 'C14.907.585.250.272'], ['E05.245', 'L01.313.500.750.190'], ['E02.642.249.285', 'G07.203.650.240.285'], ['B01.050.150.900.649.313.988.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Pre/post effectiveness evaluation of updated additional risk minimisation measures for an orphan disease: Myozyme (alglucosidase alfa) Safety Information Packet. | BACKGROUND: The alglucosidase alfa (Myozyme®) Safety Information Packet ("previous SIP") was updated to improve readability and content ("updated SIP"). We compared the previous and updated SIPs.METHODS: A two-wave pre-post multicountry survey was conducted among health care professionals (HCPs) who prescribed or monit... | ['Adolescent', 'Adult', 'Aged', 'Europe', 'Evaluation Studies as Topic', 'Female', 'Glycogen Storage Disease Type II', 'Health Personnel', 'Humans', 'Inservice Training', 'Male', 'Middle Aged', 'Risk', 'Surveys and Questionnaires', 'Young Adult', 'alpha-Glucosidases'] | 31,667,955 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['Z01.542'], ['E05.337', 'N05.715.360.335'], ['C10.228.140.163.100.435.340', 'C16.320.565.189.435.340', 'C16.320.565.202.449.500', 'C16.320.565.595.554.340', 'C18.452.132.100.435.340', 'C18.452.648.189.435.340', 'C18.452.648.202.449.500', 'C18.452.648.595.554.340'... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Purification and properties of N-acetylglucosaminide alpha 1----3-fucosyltransferase from embryonal carcinoma cells. | A membrane-bound alpha-L-fucosyltransferase, which is involved in the synthesis of a developmentally regulated carbohydrate antigen, SSEA-1, was purified about 2000-fold from F9 embryonal carcinoma cells. The procedures used were solubilization with Triton X-100, column chromatography on SP-Sephadex, DEAE-Sephadex, RCA... | ['Amino Sugars', 'Animals', 'Asialoglycoproteins', 'Cell Line', 'Electrophoresis, Polyacrylamide Gel', 'Ethylmaleimide', 'Fetuins', 'Fucosyltransferases', 'Hexosyltransferases', 'Hydrogen-Ion Concentration', 'Kinetics', 'Methionine', 'Mice', 'Molecular Weight', 'Neoplasms, Germ Cell and Embryonal', 'alpha-Fetoproteins'... | 2,423,330 | [['D09.067'], ['B01.050'], ['D12.776.395.140'], ['A11.251.210'], ['E05.196.401.402', 'E05.301.300.319'], ['D02.241.081.337.502.524.418', 'D02.478.440.418', 'D03.383.129.578.399.418'], ['D12.776.124.790.106.304', 'D12.776.157.125.283', 'D12.776.215.625', 'D12.776.377.715.085.304'], ['D08.811.913.400.450.300'], ['D08.811... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The dispensarization of population and the content of prevention activities of physicians in primary health care system]. | Nowadays, positive trends in the development of priority principle of public health organization in Russia are observed. The dispensarization of large groups of population, declared by Minzdrav of Russia, made it possible to detect a large percentage of diseases. The implemented measures produced incontestable positive... | ['Health Promotion', 'Health Status', 'Humans', 'Physicians, Primary Care', "Practice Patterns, Physicians'", 'Preventive Health Services', 'Primary Health Care', 'Public Health', 'Russia'] | 24,772,649 | [['I02.233.332.445', 'N02.421.726.407.579'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.810.800', 'N02.360.810.795'], ['N04.590.374.577', 'N05.300.625'], ['N02.421.726'], ['N04.590.233.727'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['Z01.252.... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
The provision of public-sector services by family planning agencies in 1995. | Results from a 1995 survey of a nationally representative sample of 603 publicly funded family planning agencies reveal that 96% rely on federal funding, 60% on state funding and 40% on local funding to provide family planning and other services. Although only 25% of the contraceptive clients served by these publicly f... | ['Family Planning Services', 'Financing, Government', 'Health Services Research', 'Humans', 'Medicaid', 'Minority Groups', 'Poverty', 'Public Sector', 'Surveys and Questionnaires', 'United States'] | 9,119,045 | [['N02.421.143.401', 'N02.421.800.249'], ['N03.219.521.346'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.346.506.564.655', 'N03.706.615.693'], ['I01.880.853.300'], ['I01.880.735.634', 'I01.880.853.996.535', 'N01.824.600'], ['I01.795', 'N04.452.633.8... | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Investigation of selective protein immobilization on charged protein array by wavelength interrogation-based SPR sensor. | We have investigated the use of multilayer films of polyelectrolytes as selective surfaces to analyze protein interactions with a self-assembled SPR wavelength-shift sensor. Charged arrays were prepared by alternating adsorption of the charged polyelectrolytes, poly(diallyldimethylammonium chloride) (PDDA) and poly(sod... | ['Adsorption', 'Methacrylates', 'Muramidase', 'Polyethylenes', 'Polymers', 'Protein Array Analysis', 'Protein Binding', 'Pyridines', 'Quaternary Ammonium Compounds', 'Sulfonic Acids', 'Surface Plasmon Resonance', 'Transglutaminases', 'beta-Galactosidase', 'rhoA GTP-Binding Protein'] | 12,872,989 | [['G01.030', 'G02.020'], ['D02.241.081.069.600'], ['D08.811.277.450.642'], ['D02.455.326.271.665.550', 'D05.750.716.507', 'D25.720.716.507', 'J01.637.051.720.716.507'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['E05.588.570.700', 'E05.601.680'], ['G02.111.679', 'G03.808'], ['D03.383.725'], ['D01.625.062.500', 'D02.09... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Vaginal endosonography of the anal sphincter complex is important in the assessment of faecal incontinence and perianal sepsis. | BACKGROUND: Anal endosonography is an established technique in the evaluation of anorectal disease. However, it is sometimes difficult to visualize the anterior part of the sphincter complex and anal endosonography may be impossible when anal pain or stenosis is present. The aim of this study was to evaluate vaginal en... | ['Abscess', 'Adult', 'Aged', 'Aged, 80 and over', 'Anus Diseases', 'Endosonography', 'Fecal Incontinence', 'Female', 'Humans', 'Middle Aged', 'Rectovaginal Fistula', 'Sepsis'] | 9,529,493 | [['C01.830.025', 'C23.550.470.756.100'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C06.405.469.860.101'], ['E01.370.350.850.280'], ['C06.405.469.860.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C06.267.550.600.650', 'C06.405.469.471.600.650', 'C06.405.469.860.752... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical Ethics Consultation After God: Implications for Advocacy and Neutrality. | In After God: Morality and Bioethics in a Secular Age, H. Tristram Engelhardt, Jr. explores the broad implications for moral reasoning once a culture has lost a God's-eye perspective. In this paper, I focus on the implications of Engelhardt's views for clinical ethics consultation. I begin by examining the question of ... | ['Ethical Theory', 'Ethicists', 'Ethics Consultation', 'Humanism', 'Humans', 'Patient Advocacy', 'Secularism'] | 29,063,997 | [['K01.752.566.479.118', 'N05.350.256'], ['K01.752.566.479.119', 'M01.526.276', 'N05.350.262'], ['K01.752.566.479.117.200', 'N04.452.758.849.174', 'N05.350.250.200'], ['K01.752.566.479.174', 'N05.350.835'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.631', 'N03.706.678'], ['I01.880.853.350', 'K01.922... | ['Humanities [K]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Event-related rTMS at encoding affects differently deep and shallow memory traces. | The "level of processing" effect is a classical finding of the experimental psychology of memory. Actually, the depth of information processing at encoding predicts the accuracy of the subsequent episodic memory performance. When the incoming stimuli are analyzed in terms of their meaning (semantic, or deep, encoding),... | ['Adult', 'Brain', 'Female', 'Humans', 'Male', 'Memory', 'Task Performance and Analysis', 'Transcranial Magnetic Stimulation', 'Young Adult'] | 20,601,000 | [['M01.060.116'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600'], ['E02.621.820'], ['M01.060.116.815']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Serial determinations of cerebral water content by magnetic resonance imaging after an infusion of hypertonic saline. | OBJECTIVE: To determine regional cerebral water content in vivo by magnetic resonance imaging (MRI) after the administration of 7.5% saline in brain-lesioned rabbits.DESIGN: Randomized, controlled, intervention trial.SETTING: University animal laboratory.SUBJECTS: Eighteen male New Zealand white rabbits, randomly assig... | ['Animals', 'Body Water', 'Brain', 'Brain Edema', 'Disease Models, Animal', 'Infusions, Intravenous', 'Magnetic Resonance Imaging', 'Male', 'Organ Size', 'Osmolar Concentration', 'Rabbits', 'Random Allocation', 'Saline Solution, Hypertonic'] | 9,428,551 | [['B01.050'], ['A12.207.200'], ['A08.186.211'], ['C10.228.140.187'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['E01.370.350.825.500'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690'], ['G02.640'], ['B01.050.150.900.649.313.968.70... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Role of environmental pollution with heavy metals in chronic pulmonary diseases pathogenesis in North regions]. | Accumulation of Cu, Zn, Mn, Ni, Pb, Cd in biologic materials causes microelements imbalance and metabolic disorders affecting also redox reactions, immune system and respiratory organs and functions, therefore leading to chronic pulmonary diseases. The authors suggested a hypothesis on links between environmental pollu... | ['Adolescent', 'Adult', 'Catchment Area, Health', 'Chronic Disease', 'Environmental Pollution', 'Heavy Metal Poisoning', 'Humans', 'Lung Diseases', 'Middle Aged', 'Occupational Diseases', 'Russia'] | 15,490,622 | [['M01.060.057'], ['M01.060.116'], ['N01.224.791.200', 'N03.349.650.095', 'N06.850.505.400.800.200'], ['C23.550.291.500'], ['N06.850.460'], ['C25.723.522'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381'], ['M01.060.116.630'], ['C24'], ['Z01.252.122.500', 'Z01.542.248.775']] | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Platinum nanoparticles-doped sol-gel/carbon nanotubes composite electrochemical sensors and biosensors. | Platinum nanoparticle-doped sol-gel solution is prepared and used as a binder for multi-walled carbon nanotubes (CNT) for the fabrication of electrochemical sensors. Amine group containing sol-gel solution is selected to utilize the affinity of -NH(2) groups toward metal nanoparticles for stabilization the nanoparticle... | ['Adsorption', 'Biosensing Techniques', 'Coated Materials, Biocompatible', 'Electrochemistry', 'Enzymes, Immobilized', 'Equipment Design', 'Equipment Failure Analysis', 'Glucose', 'Glucose Oxidase', 'Hydrogen Peroxide', 'Nanotubes, Carbon', 'Ointments', 'Particle Size', 'Phase Transition', 'Platinum', 'Transducers'] | 15,885,999 | [['G01.030', 'G02.020'], ['E05.601.043'], ['D25.130.420', 'J01.637.051.130.420'], ['H01.181.529.307'], ['D08.811.180', 'D12.776.463.500'], ['E05.320'], ['E05.325.192'], ['D09.947.875.359.448'], ['D08.811.682.047.239'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Clinical characteristics, treatment and outcome of 28 oral haemangiomas in pediatric patients. | OBJECTIVE: To present a large series of oral haemangiomas in children, analyzing the clinical characteristics, treatment and outcome of oral haemangiomas in 28 children.MATERIAL AND METHODS: We conducted an observational retrospective study, reviewing medical records with clinical diagnosis of haemangioma between 1990 ... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Hemangioma', 'Humans', 'Infant', 'Male', 'Mouth Neoplasms', 'Retrospective Studies', 'Treatment Outcome'] | 20,711,165 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['C04.557.645.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04.588.443.591', 'C07.465.530'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Using nylon strips to dispense mosquito attractants for sampling the malaria vector Anopheles gambiae s.s. | Synthetic versions of human derived kairomones can be used as baits when trapping host seeking mosquitoes. The effectiveness of these lures depends not only on their attractiveness to the mosquitoes but also on the medium from which they are dispensed. We report on the development and evaluation of nylon strips as a me... | ['Animals', 'Anopheles', 'Behavior, Animal', 'Glass', 'Humans', 'Insect Vectors', 'Malaria', 'Mosquito Control', 'Nylons', 'Pheromones', 'Pheromones, Human', 'Polyethylene'] | 20,380,310 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['F01.145.113'], ['J01.637.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['C01.610.752.530', 'C01.920.875'], ['N06.850.780.200.650.425.500'], ['D05.750.716.392', 'D25.720.716.392'... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
High stocking density alters bone-related calcium and phosphorus metabolism by changing intestinal absorption in broiler chickens. | Live performance, bone health and metabolic responses to the interaction among stocking density and dietary concentrations of total calcium (TCa) and non-phytate phosphorus (NPP) were determined on 2,232 Ross 308 female broilers over a 3-wk experimental period. From 22 d of age, birds were randomly divided into 48 grou... | ['Animal Feed', 'Animal Husbandry', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Calcium, Dietary', 'Chickens', 'Diet', 'Dietary Supplements', 'Digestion', 'Dose-Response Relationship, Drug', 'Female', 'Intestinal Absorption', 'Phosphorus, Dietary', 'Population Density', 'Random Allocation'] | 29,112,750 | [['G07.203.300.300.100', 'J02.500.300.100'], ['J01.040.090'], ['G07.203.650.161'], ['B01.050'], ['D01.146.395'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G07.203.650.240'], ['G07.203.300.456', 'J02.500.456'], ['G07.203.650.250', 'G10.261.190'], ['G07.690.773.875', 'G07.690.936.500'], ['G03.015.... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Peptides and neuromas: calcitonin gene-related peptide, substance P, and mast cells in a mechanosensitive human sural neuroma. | We examined and compared a mechanosensitive human sural neuroma and a contralateral sural nerve collected simultaneously from a patient involved in a diabetic neuropathy research protocol. Using indirect immunofluorescence staining. we identified a striking difference in the content within axons of two neuropeptides, s... | ['Antibody Specificity', 'Biopsy', 'Calcitonin Gene-Related Peptide', 'Double-Blind Method', 'Humans', 'Male', 'Mast Cells', 'Mechanoreceptors', 'Middle Aged', 'Multicenter Studies as Topic', 'Myelin Sheath', 'Neuroma', 'Neurons', 'Pain', 'Peripheral Nervous System Neoplasms', 'Randomized Controlled Trials as Topic', '... | 9,179,160 | [['G12.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D12.644.400.097', 'D12.776.631.650.097'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficacy of addition of nepafenac 0.1% to steroid eye drops in prevention of post-phaco macular edema in high-risk eyes. | PURPOSE: To compare the efficacy of addition of nonsteroidal anti-inflammatory eye drops to steroidal eye drops with that of using postoperative steroidal anti-inflammatory eye drops alone in prevention of macular edema in high-risk patients.SETTING: Cairo University Hospital.DESIGN: This study was comparative prospect... | ['Adult', 'Aged', 'Anti-Inflammatory Agents, Non-Steroidal', 'Benzeneacetamides', 'Cataract', 'Drug Combinations', 'Female', 'Glucocorticoids', 'Humans', 'Lens Implantation, Intraocular', 'Macular Edema', 'Male', 'Middle Aged', 'Ophthalmic Solutions', 'Phacoemulsification', 'Phenylacetates', 'Postoperative Complication... | 30,203,671 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D02.065.064.294', 'D02.455.426.559.389.048'], ['C11.510.245'], ['D26.310'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.540.825.600'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Is ureteral dilatation necessary in ureterorenoscopy?]. | A retrospective analysis of 136 patients, who were submitted rigid ureteroscopy for stone removal, was performed. Patients were divided into two groups. First group consisted of 63 patients with routine balloon dilation of intramural part of ureter before ureteroscopy. 73 patients of the second group were submitted ure... | ['Adult', 'Aged', 'Aged, 80 and over', 'Catheterization', 'Female', 'Humans', 'Male', 'Middle Aged', 'Ureteral Calculi', 'Ureteroscopy'] | 8,629,155 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.148', 'E05.157'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C12.777.725.938.500', 'C12.777.967.374.500', 'C12.777.967.500.851', 'C13.351.968.725.938.500', 'C13.351.968.967.374.500', 'C13.351.968.967.500.851', 'C23.300.17... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical utilization of injectable collagen. | The applications for an injectable, highly purified form of calfhide collagen (Zyderm Collagen Implant) were first described by Knapp et al in 1977. Since that time, the material has undergone evaluation in a nationwide clinical trial in which 728 physicians participated under a cooperative protocol. In these trials--w... | ['Acne Vulgaris', 'Aging', 'Atrophy', 'Cicatrix', 'Collagen', 'Facial Asymmetry', 'Humans', 'Injections, Subcutaneous', 'Postoperative Complications', 'Skin', 'Skin Transplantation'] | 6,224,455 | [['C17.800.030.150', 'C17.800.794.111'], ['G07.345.124'], ['C23.300.070'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['D05.750.078.280', 'D12.776.860.300.250'], ['C23.300.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.620'], ['C23.550.767'], ['A17.815'], ['E02.095.147.725.700... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of age and body mass index on gamma-glutamyltransferase activity: a 15-year follow-up evaluation in a community sample. | Most clinicians and researchers view serum gamma-glutamyltransferase (GGT) activity as a measure that can be interpreted equally in patients regardless of their demography. The present study evaluates the concurrent influence of age and body mass index (BMI) on GGT in a sample of 133 high functioning young men, with de... | ['Adult', 'Age Factors', 'Alcoholism', 'Body Mass Index', 'Child of Impaired Parents', 'Follow-Up Studies', 'Humans', 'Male', 'Reference Values', 'Risk Factors', 'Sensitivity and Specificity', 'gamma-Glutamyltransferase'] | 9,660,326 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C25.775.100.250', 'F03.900.100.350'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.106'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.31... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cell biological analysis of DT40 knockout cell lines for cell-cycle genes. | DT40 is a chicken B cell line that has been widely used as a model for gene functional studies because the high level of homologous recombination in DT40 cells allows targeted disruption of a gene of interest. While our laboratory uses DT40 cells to understand kinetochore assembly and function, the approach is applicab... | ['Animals', 'Cell Cycle', 'Cell Line', 'Chickens', 'Flow Cytometry', 'Gene Knockout Techniques', 'Genes, cdc'] | 21,400,701 | [['B01.050'], ['G04.144'], ['A11.251.210'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['E05.393.335.750'], ['G05.360.340.024.34... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of GPX4 on proliferation and metastasis of renal clear cell carcinoma and its relationship with expression of IGF-1R and COX-2]. | Objective: To investigate the effect of human glutathione peroxidase 4 (GPX4) on the proliferation and metastasis of renal clear cell carcinoma and its relationship with the expression of IGF-1R and COX-2. Methods: Culture of human normal tubular cell line HK-2 and human renal clear cell carcinoma Caki-1, A498, Caki-2,... | ['Carcinoma, Renal Cell', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Cyclooxygenase 2', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Kidney Neoplasms', 'Neoplasm Invasiveness', 'Phospholipid Hydroperoxide Glutathione Peroxidase', 'Receptor, IGF Type 1', 'Receptors, Somatomedin'] | 31,818,070 | [['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D08.811.600.720.750'], ['G05.308.370'], ['B01.050... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A causal role for the extrastriate body area in detecting people in real-world scenes. | People are extremely efficient at detecting relevant objects in complex natural scenes. In three experiments, we used functional magnetic resonance imaging-guided transcranial magnetic stimulation (TMS) to investigate the role of the extrastriate body area (EBA) in the detection of people in scenes. In Experiment 1, pa... | ['Analysis of Variance', 'Brain Mapping', 'Discrimination, Psychological', 'Female', 'Functional Laterality', 'Human Body', 'Humans', 'Male', 'Photic Stimulation', 'Reaction Time', 'Transcranial Magnetic Stimulation', 'Visual Cortex', 'Visual Perception', 'Young Adult'] | 23,595,757 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.593.257'], ['F02.830.297.425', 'G11.561.225.425'], ['I01.076.201.450.560', 'K01.093.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.723.729'], ['E05.796.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Effects of dextran sulfate on stabilization of milk lipoprotein lipase and VLDL triglyceride hydrolysis in vitro. | The effects of dextran sulfate (DS), which has various molecular numbers, on hydrolysis of very low density lipoprotein triglyceride (VLDL-TG) by bovine milk lipoprotein lipase (LPL) and the stability of LPL were studied. VLDL-TG hydrolysis was increased by the addition of DS; DS caused linear increase in the Vmax for ... | ['Animals', 'Cattle', 'Dextran Sulfate', 'Dextrans', 'In Vitro Techniques', 'Kinetics', 'Lipoprotein Lipase', 'Lipoproteins, VLDL', 'Milk', 'Molecular Weight', 'Structure-Activity Relationship', 'Triglycerides'] | 2,426,843 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D09.698.365.272.300'], ['D05.750.078.562.272', 'D09.698.365.272'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['D08.811.277.352.100.430'], ['D10.532.599', 'D12.776.521.622'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Serum levels of soluble CD23 in patients with bullous pemphigoid. | In this study, we tested the serum levels of soluble CD23 (sCD23) in 27 bullous pemphigoid (BP) patients and compared them with the disease activity. Soluble CD23 is the cleaved portion of the low affinity Fc receptor for IgE (Fc epsilon RII/CD23) which has an affinity for IgE and regulates IgE synthesis. Although bull... | ['Anti-Inflammatory Agents', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Glucocorticoids', 'Humans', 'Immunoglobulin E', 'Male', 'Pemphigoid, Bullous', 'Prognosis', 'Receptors, IgE', 'Severity of Illness Index', 'Steroids'] | 7,673,549 | [['D27.505.954.158'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Using community health profiles to improve service provision. | Profiling has become increasingly important to the purchasing and provision of todays' health care. Kate Cernik and Mandy Wearne examine the concept and its importance to health visitors and community nurses and ask what is involved in the profiling process and who should be doing it. | ['Community Health Nursing', 'Health Services Needs and Demand', 'Humans', 'Marketing of Health Services', 'Nursing Assessment', 'Quality of Health Care'] | 1,478,871 | [['H02.478.676.150', 'N02.421.143.150'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.219.687.550', 'N03.219.463.548', 'N05.300.430.500'], ['N04.590.233.508.480'], ['N04.761', 'N05.715']] | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Sentinel lymph node biopsy for patients with cutaneous desmoplastic melanoma. | BACKGROUND: Although desmoplastic melanoma (DM) often presents at a locally advanced stage, nodal metastases are rare. We describe our experience with lymphatic mapping and sentinel lymph node biopsy (SLNB) in patients with DM to characterize the biological behavior of these tumors.METHODS: Twenty-seven patients with c... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Male', 'Melanoma', 'Middle Aged', 'Sentinel Lymph Node Biopsy', 'Skin Neoplasms'] | 12,734,089 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['M01.060.116.630'], ['E01.370.225.500.384.100.580', 'E01.370.225.998.054.580', 'E01.370.388.100.580', 'E04.074.580... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sex differences in long-term gonadectomized rats: monoamine levels and [3H]nitroimipramine binding in brain nuclei. | The levels of norepinephrine, dopamine, serotonin and the serotonin metabolite 5-hydroxyindoleacetic acid were measured in microdissected brain nuclei from long-term gonadectomized male and female rats. Females had 50 and 120% higher levels of serotonin in the anterior hypothalamic nucleus (AH) and arcuate-median emine... | ['Animals', 'Binding Sites', 'Biogenic Amines', 'Castration', 'Dopamine', 'Female', 'Hydroxyindoleacetic Acid', 'Imipramine', 'Limbic System', 'Male', 'Norepinephrine', 'Rats', 'Rats, Inbred Strains', 'Serotonin', 'Sex Characteristics'] | 2,580,732 | [['B01.050'], ['G02.111.570.120'], ['D02.092.211'], ['E04.270.282', 'E04.950.165'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D03.066.288.478', 'D03.633.100.473.404.478'], ['D03.633.300.240.485'], ['A08.186.211.180'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Seemingly diverse activities of beta-alethine. | beta-Alethine (beta-alanyl-cysteamine disulfide) exhibits striking biological activities in diverse systems. At an optimum of about 10 ng/ml, beta-alethine (a) adapts murine liver cells to culture (53 colonies/10(6) cells versus none in controls), (b) delays aging of human IMR-90 fetal lung fibroblasts (102 population ... | ['Animals', 'Antibody Formation', 'Cell Line', 'Cells, Cultured', 'Cellular Senescence', 'Cysteamine', 'Dose-Response Relationship, Drug', 'Drug Screening Assays, Antitumor', 'Female', 'Fibroblasts', 'Humans', 'Leukocytes', 'Lymphocytes', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Multiple Myeloma'] | 7,923,209 | [['B01.050'], ['G12.450.050.370.250'], ['A11.251.210'], ['A11.251'], ['G04.043'], ['D02.092.471.562.369', 'D02.886.489.472.369'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phosphatidylkojibiosyl diglyceride. The covalently linked lipid constituent of the membrane lipoteichoic acid from Streptococcus faecalis (faecium) ATCC 9790. | Water-soluble [14C]glycerol-labeled lipoteichoic acid isolated from the membrane preparations of Streptococcus faecalis (faecium) ATCC 9790 released chloroform-soluble radioactivity upon mild acid hydrolysis. Chromatography of the radioactive, chloroform-extractable material revealed the presence of a very polar lipid ... | ['Carbon Radioisotopes', 'Cell Membrane', 'Chromatography, Gel', 'Diglycerides', 'Disaccharides', 'Enterococcus faecalis', 'Glycerol', 'Glycolipids', 'Lipopolysaccharides', 'Phosphatidylglycerols', 'Phospholipids', 'Spectrophotometry, Ultraviolet', 'Teichoic Acids'] | 803,497 | [['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['A11.284.149'], ['E05.196.181.400.250'], ['D10.351.303'], ['D09.698.629.305', 'D09.947.750'], ['B03.353.750.250.250.280', 'B03.510.550.250.250.280'], ['D02.033.800.875.500', 'D09.853.875.500'], ['D09.400.410', 'D10.390'], ['D09.400.500', 'D09.698.718.450'... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Identification of metabolites of epiberberine in rat liver microsomes and its inhibiting effects on CYP2D6]. | Epiberberine, one of the most important isoquinoline alkaloid in Coptidis Rhizoma, possesses extensive pharmacological activities. In this paper, the liquid chromatography-tandem mass spectrometry (LC-MS/MS) was used to study phase I and phase II metabolites. A Thermo HPLC system (including Surveyor AS, Surveyor LC Pum... | ['Animals', 'Berberine', 'Chromatography, High Pressure Liquid', 'Cytochrome P-450 CYP2D6', 'Cytochrome P-450 CYP2D6 Inhibitors', 'Drugs, Chinese Herbal', 'Male', 'Microsomes, Liver', 'Molecular Structure', 'Rats', 'Rats, Sprague-Dawley', 'Tandem Mass Spectrometry'] | 25,612,454 | [['B01.050'], ['D03.132.098.057.100', 'D03.633.400.168.100'], ['E05.196.181.400.300'], ['D08.244.453.005.600', 'D08.244.453.491.372', 'D08.811.682.690.708.170.010.600', 'D08.811.682.690.708.170.450.368', 'D12.776.422.220.453.010.600', 'D12.776.422.220.453.491.368'], ['D27.505.389.500.368', 'D27.505.519.389.335.368'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Functional consequences of detubulation of isolated rat ventricular myocytes. | OBJECTIVE: Recent work has suggested that Na(+)/Ca(2+) exchange (NCX) and L-type Ca(2+) current (I(Ca)) are located predominantly in the t-tubules of cardiac ventricular myocytes, which therefore represent a microdomain for the regulation of intracellular Na(+) (Na(i)) and Ca(2+) (Ca(i)). The aim of this study was to i... | ['Animals', 'Calcium', 'Cell Size', 'Cells, Cultured', 'Heart Ventricles', 'Male', 'Microscopy, Fluorescence', 'Muscle Fibers, Skeletal', 'Myocytes, Cardiac', 'Rats', 'Rats, Wistar', 'Sarcolemma', 'Sodium', 'Stimulation, Chemical', 'Strophanthidin', 'Tetrodotoxin'] | 15,158,145 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.325'], ['A11.251'], ['A07.541.560'], ['E01.370.350.515.458', 'E05.595.458'], ['A10.690.552.500.500', 'A11.620.249'], ['A07.541.704.570', 'A10.690.552.750.570', 'A11.620.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.31... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Two-dimensional NMR analysis of Angiopteris evecta rhizome and improved extraction method for angiopteroside. | INTRODUCTION: The rhizome of Angiopteris evecta is of academic interest in Kalimantan, Indonesia, from an ethnobotanical perspective. Angiopteroside is a substance of pharmaceutical importance that is found in the rhizome of A. evecta.OBJECTIVE: The aims of this research are to improve the extraction method for angiopt... | ['Anti-Bacterial Agents', 'Bacillus subtilis', 'Chromatography, Liquid', 'Escherichia coli', 'Klebsiella pneumoniae', 'Lignin', 'Magnetic Resonance Spectroscopy', 'Mass Spectrometry', 'Microbial Sensitivity Tests', 'Molecular Structure', 'Rhizome', 'Sugars', 'Tracheophyta'] | 30,255,625 | [['D27.505.954.122.085'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['E05.196.181.400'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B03.440.450.425.425.600', 'B03.660.250.150.400.590'], ['D05.750.07... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
USB-based Personal Health Records: an analysis of features and functionality. | PURPOSE: To determine the features of commercially available USB-based Personal Health Records (PHR) devices, and compare the commercial state of the art to recommendations made by certification committees.METHODS: Thirteen USB-based PHRs were identified and analyzed based on data elements used and features provided. M... | ['Computer Security', 'Confidentiality', 'Databases, Factual', 'Health Records, Personal', 'Humans', 'Medical Records Systems, Computerized', 'Quality Assurance, Health Care'] | 20,053,582 | [['L01.224.134', 'N04.452.910.200'], ['F04.096.544.335.240', 'I01.880.604.473.650.500', 'I01.880.604.583.080', 'N03.706.437.650.124', 'N03.706.535.230'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E05.318.308.940.968.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.940.968.625', 'L01.313... | ['Information Science [L]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice. | Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative condition characterized by motoneuron degeneration and muscle paralysis. Although the precise pathogenesis of ALS remains unclear, mutations in Cu/Zn superoxide dismutase (SOD1) account for approximately 20-25% of familial ALS cases, and transgenic mice o... | ['Amyotrophic Lateral Sclerosis', 'Animals', 'Axonal Transport', 'Axons', 'Disease Models, Animal', 'Disease Progression', 'Dyneins', 'Female', 'Humans', 'Male', 'Mice', 'Mice, Neurologic Mutants', 'Mice, Transgenic', 'Motor Neurons', 'Mutation', 'Nerve Degeneration', 'Recovery of Function', 'Superoxide Dismutase', 'Su... | 15,911,875 | [['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['B01.050'], ['G03.143.355.040', 'G04.392.040', 'G11.561.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.291.656'], ['D08.811.27... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
It's plain and simple: transparency is good for science and in the public interest. | In the past couple of years, there has been a growing focus on the need to make scientific output accessible to a greater number of people, especially in the field of clinical research. The public are being urged to become more well-informed and to ask their doctors about taking part in clinical trials. A key finding o... | ['Access to Information', 'Biomedical Research', 'Clinical Trials as Topic', 'Comprehension', 'Disclosure', 'Guidelines as Topic', 'Health Knowledge, Attitudes, Practice', 'Health Literacy', 'Humans', 'Language', 'Public Opinion', 'Research Design', 'Research Subjects'] | 23,849,479 | [['I01.880.604.473.352.500.030', 'L01.143.024', 'L01.737.030'], ['H01.770.644.145'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['F02.463.188.357'], ['F01.829.401.046', 'I01.880.604.583.080.134', 'L01.143.335'], ['N04.761.700.350', 'N05.700.350'], ['F01.100.150.500', 'N05.300.150.410... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
[A case of bilateral atrial myxoma]. | A case of 47-year-old female who underwent the surgery for the bilateral atrial myxoma two times was reported. At the first operation both tumors were attached to the same level of the atrial septum and were removed simultaneously followed by the resection of the left atrial wall. Six months later, she complained of dy... | ['Female', 'Heart Atria', 'Heart Neoplasms', 'Humans', 'Middle Aged', 'Myxoma', 'Neoplasm Recurrence, Local', 'Reoperation'] | 2,352,401 | [['A07.541.358'], ['C04.588.894.309', 'C14.280.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.450.565.550'], ['C04.697.655', 'C23.550.727.655'], ['E04.690']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Direct effects of fermented cow's milk product with Lactobacillus paracasei CBA L74 on human enterocytes. | Cow's milk fermented with Lactobacillus paracasei CBA L74 (FM-CBAL74) exerts a preventive effect against infectious diseases in children. We evaluated if this effect is at least in part related to a direct modulation of non-immune and immune defence mechanisms in human enterocytes. Human enterocytes (Caco-2) were stimu... | ['Antimicrobial Cationic Peptides', 'Caco-2 Cells', 'Cell Differentiation', 'Cell Proliferation', 'Cultured Milk Products', 'Enterocytes', 'Gene Expression Regulation', 'Humans', 'Lactobacillus paracasei', 'Mucin-2', 'Occludin', 'Probiotics', 'Tight Junctions', 'Toll-Like Receptors', 'Zonula Occludens-1 Protein', 'beta... | 29,065,709 | [['D12.644.050', 'D12.776.543.695.054'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['G07.203.200.500', 'G07.203.300.350.300', 'J02.350.500', 'J02.500.350.300'], ['A03.556.124.369.290', 'A10.615.550.444.290', 'A11.436.290'], ['G05.308'], ['B01.050... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
First-trimester prenatal diagnosis of hypophosphatasia: experience with 16 cases. | We have carried out first-trimester prenatal diagnosis of hypophosphatasia in 16 pregnancies with a 1 in 4 risk of this condition. The liver/bone/kidney isoenzyme of alkaline phosphatase was measured in chorionic villus samples using a specific monoclonal antibody and an enzymatic amplification system. Fifteen of the 1... | ['Alkaline Phosphatase', 'Antibodies, Monoclonal', 'Chorionic Villi Sampling', 'Female', 'Humans', 'Hypophosphatasia', 'Pregnancy', 'Pregnancy Trimester, First', 'Reproducibility of Results'] | 1,924,179 | [['D08.811.277.352.650.035'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E01.370.225.500.384.100.149', 'E01.370.225.998.054.149', 'E01.370.378.630.150', 'E01.370.388.100.150', 'E04.074.149', 'E05.200.500.384.100.149', 'E05.200.998.054.149', 'E05.242.384.100.149'], [... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Burnout and perceived social support: The mediating role of secondary traumatization in nurses vs. physicians. | AIMS: The study aimed to examine differences between paediatric nurses and physicians regarding burnout syndrome, secondary traumatic stress (STS) and perceived social support (PSS).BACKGROUND: Paediatric nurses and physicians encounter cumulative effects of treating sick and injured children and helping their families... | ['Adult', 'Burnout, Professional', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nurses', 'Physicians', 'Social Support', 'Young Adult'] | 31,231,845 | [['M01.060.116'], ['C24.580.500', 'F01.145.126.990.367.500', 'F02.830.900.333.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.526.485.650', 'N02.360.650'], ['M01.526.485.810', 'N02.360.810'], ['I01.880.853.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Effects of cerium nitrate bathing and prompt burn wound excision on IL-6 and TNF-alpha levels in burned rats. | The physiopathological events following thermal injury are not limited to the surface effects of heat but are also related to acute inflammatory reactions. Both tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) are important mediators of the acute and severe inflammatory reaction in thermal injury. Surg... | ['Animals', 'Anti-Infective Agents, Local', 'Baths', 'Burns', 'Cerium', 'Debridement', 'Interleukin-6', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Tumor Necrosis Factor-alpha'] | 10,630,318 | [['B01.050'], ['D27.505.954.122.187'], ['E02.056.110'], ['C26.200'], ['D01.268.558.362.249', 'D01.552.550.399.249'], ['E04.176'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['D12.644.276.374... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Stress-Metabolic Syndrome Relationship in Adolescents: An Examination of the Moderating Potential of Physical Activity. | BACKGROUND: The role of psychosocial stress in the development of obesity and metabolic syndrome is receiving increased attention and has led to examination of whether physical activity may moderate the stress-metabolic syndrome relationship. The current study examined relationships among physical activity, stress, and... | ['Adolescent', 'Anthropometry', 'Blood Pressure', 'Body Height', 'Body Mass Index', 'Child', 'Exercise', 'Female', 'Humans', 'Male', 'Metabolic Syndrome', 'Regression Analysis', 'Stress, Psychological', 'Waist Circumference'] | 27,254,850 | [['M01.060.057'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Intravenous versus oral ganciclovir: European/Australian comparative study of efficacy and safety in the prevention of cytomegalovirus retinitis recurrence in patients with AIDS. The Oral Ganciclovir European and Australian Cooperative Study Group. | OBJECTIVES: To evaluate the efficacy and safety of oral ganciclovir for the maintenance treatment of cytomegalovirus (CMV) retinitis in patients with AIDS.DESIGN: A 20-week, randomized, multicentre, open-label study. Progression of retinitis was assessed by funduscopy and masked reading of fundus photographs.METHODS: A... | ['AIDS-Related Opportunistic Infections', 'Administration, Oral', 'Adult', 'Australia', 'Cytomegalovirus Retinitis', 'Diarrhea', 'Disease Progression', 'Drug Evaluation', 'Europe', 'Female', 'Ganciclovir', 'Humans', 'Injections, Intravenous', 'Male', 'Middle Aged', 'Neutropenia', 'Recurrence', 'Time Factors', 'Treatmen... | 7,639,972 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['E02.319.267.100'], ['M01.060.116'], ['Z01.639.100', 'Z01.678.100.373'], ['C01.375.725.270', 'C01.925.256.466.245.150', 'C01.925.325.270', 'C11.294.800.270', 'C11.768.773.360'], ['C23.888.82... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Efficacy and outcomes of transobturator tension-free vaginal tape with or without concomitant pelvic floor repair surgery for urinary stress incontinence: five-year follow-up. | OBJECTIVES: To compare the 5-year subjective and objective outcomes of transobturator tension-free vaginal tape alone versus the same procedure with concomitant pelvic floor repair surgery for pelvic organ prolapse in women with urinary stress incontinence.DESIGN: Prospective cohort study.SETTING: Urogynaecology unit a... | ['Adult', 'Aged', 'Female', 'Follow-Up Studies', 'Humans', 'Middle Aged', 'Pelvic Floor', 'Pelvic Organ Prolapse', 'Prospective Studies', 'Suburethral Slings', 'Treatment Outcome', 'Urinary Incontinence, Stress', 'Vagina'] | 26,183,453 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A01.923.600.600', 'A02.633.567.050.750'], ['C23.300.842.624'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.65... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Trauma-Informed Care Is the Best Clinical Practice in Rehabilitation Nursing. | PURPOSE: This clinical article explores how trauma-informed care (TIC) can be used by rehabilitation nurses with patients who have experienced pervasive adverse childhood experiences (ACEs).METHOD (INTERVENTION STRATEGIES): This clinical article gives suggestions for using the five guiding principles of TIC: safety, tr... | ['Humans', 'Life Change Events', 'Practice Guidelines as Topic', 'Rehabilitation Nursing', 'Wounds and Injuries'] | 29,499,004 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458.410'], ['N04.761.700.350.650', 'N05.700.350.650'], ['H02.478.676.789', 'N02.421.533.889'], ['C26']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Impact of extreme prematurity on families of adolescent children. | OBJECTIVES: To compare the impact of burden of illness on families of teenaged children who were extremely low birth weight (ELBW) with that of members of a term control group (C) and to determine whether the attitudes toward active treatment of very immature infants differ between the 2 cohorts.DESIGN: In a cross-sect... | ['Adaptation, Psychological', 'Adolescent', 'Cohort Studies', 'Cost of Illness', 'Cross-Sectional Studies', 'Decision Making', 'Developmental Disabilities', 'Ethics, Medical', 'Family', 'Humans', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Infant, Premature', 'Intensive Care, Neonatal'] | 11,060,538 | [['F01.058'], ['M01.060.057'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F02.463.785.373'], ['F03.625.421'], ['... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Prospective 3D analysis of facial soft tissue augmentation with calcium hydroxylapatite. | BACKGROUND: Facial rejuvenation is an expanding field with an increasing number of treatment modalities. Several non-autologous filler materials are available for soft tissue augmentation. Calcium hydroxylapatite (CaOH) is aimed at increasing collagen neosynthesis and thereby producing long-term augmentation effects. D... | ['Aged', 'Aging', 'Dermal Fillers', 'Durapatite', 'Face', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Middle Aged', 'Patient Satisfaction', 'Photography', 'Rejuvenation', 'Time Factors'] | 28,328,289 | [['M01.060.116.100'], ['G07.345.124'], ['D27.720.102.461'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Structural basis for the temperature-induced transition of D-amino acid oxidase from pig kidney revealed by molecular dynamic simulation and photo-induced electron transfer. | The structural basis for the temperature-induced transition in the D-amino acid oxidase (DAAO) monomer from pig kidney was studied by means of molecular dynamic simulations (MDS). The center to center (Rc) distances between the isoalloxazine ring (Iso) and all aromatic amino acids (Trp and Tyr) were calculated at 10 °C... | ['Animals', 'D-Amino-Acid Oxidase', 'Electrons', 'Hydrogen Bonding', 'Kidney', 'Molecular Dynamics Simulation', 'Photochemistry', 'Protein Conformation', 'Temperature'] | 22,273,818 | [['B01.050'], ['D08.811.682.664.500.125'], ['G01.249.335', 'G01.358.500.750'], ['G02.282'], ['A05.810.453'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['H01.181.529.711'], ['G02.111.570.820.709'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
A Cross-Correlated Delay Shift Supervised Learning Method for Spiking Neurons with Application to Interictal Spike Detection in Epilepsy. | This study introduces a novel learning algorithm for spiking neurons, called CCDS, which is able to learn and reproduce arbitrary spike patterns in a supervised fashion allowing the processing of spatiotemporal information encoded in the precise timing of spikes. Unlike the Remote Supervised Method (ReSuMe), synapse de... | ['Action Potentials', 'Cerebral Cortex', 'Epilepsy', 'Humans', 'Neural Inhibition', 'Neural Networks, Computer', 'Neurons', 'Supervised Machine Learning', 'Synapses', 'Time Factors', 'Wavelet Analysis'] | 27,785,934 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['A08.186.211.200.885.287.500'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.265.755', 'G11.561.616'], ['G17.485', 'L01.224.050.375.605'], ['A08.675', 'A11.671'], ['G17.035.250.500.500', 'L01.224.050.375.530.500'], ['A08.850', 'A11.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Regional variations of muscle fibre characteristic in m. semitendinosus of growing cattle. | The objectives of the present study were to elaborate an intra-muscular profile of metabolic enzyme equipment, contractile and morphometric features along the longitudinal axis of m. semitendinosus at various ages throughout the growth phase. Thirty-seven male Montb?liard cattle, about half of them castrated, were repr... | ['Aging', 'Animals', 'Cattle', 'Enzyme-Linked Immunosorbent Assay', 'Isocitrate Dehydrogenase', 'L-Lactate Dehydrogenase', 'Male', 'Muscle Fibers, Skeletal', 'Myosin Heavy Chains'] | 9,147,993 | [['G07.345.124'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D08.811.682.047.820.475'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['A10.690.552.500.500', 'A11.620.249'], ['D05.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transplants of fetal neural tissue and autologous peripheral nerves in an attempt to repair spinal cord injuries in the adult rat. An overall view. | Embryonic neurons and autologous peripheral nerve segments constitute selected materials for studying central nervous system plasticity and repair in adult mammals. Transplanted to the brain or the spinal cord, the former are possible substitutes designed to replace lost or deficient host neurons while the latter have ... | ['Animals', 'Fetal Tissue Transplantation', 'Nerve Tissue', 'Neurons', 'Peripheral Nerves', 'Rats', 'Spinal Cord Injuries', 'Transplantation, Autologous'] | 1,886,729 | [['B01.050'], ['E02.095.147.725.300', 'E04.936.580.300'], ['A10.755'], ['A08.675', 'A11.671'], ['A08.800.800'], ['B01.050.150.900.649.313.992.635.505.700'], ['C10.228.854.763', 'C10.900.850', 'C26.819'], ['E04.936.664']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Sp1 transcription factor is essential for the expression of gliostatin/thymidine phosphorylase in rheumatoid fibroblast-like synoviocytes. | INTRODUCTION: Gliostatin/thymidine phosphorylase (GLS/TP) has angiogenic and arthritogenic activities, and aberrant GLS production has been observed in the active synovial membranes of rheumatoid arthritis (RA) patients. The human GLS gene promoter contains at least seven consensus binding sites for the DNA binding pro... | ['Aged', 'Arthritis, Rheumatoid', 'Cells, Cultured', 'Female', 'Fibroblasts', 'Gene Expression Regulation', 'Humans', 'Male', 'Middle Aged', 'Promoter Regions, Genetic', 'Sp1 Transcription Factor', 'Synovial Fluid', 'Thymidine Phosphorylase'] | 22,534,375 | [['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['A11.251'], ['A11.329.228'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['D12.776.260.522.750.249', ... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The action of scopolamine on retrieval and memory storage in rats evaluated in the staircase maze. | Rats were trained to run on staircase stopping on the 3rd, 6th, 9th, and 12th steps (correct responses). Stopping on any other step was considered an error. The acute administration of scopolamine (1.5 mg/kg) 20 min before the trial caused a reduction of the correct responses. An interruption of the daily training for ... | ['Animals', 'Behavior, Animal', 'Conditioning, Psychological', 'Discrimination Learning', 'Male', 'Memory', 'Rats', 'Scopolamine'] | 8,442,729 | [['B01.050'], ['F01.145.113'], ['F02.463.425.179'], ['F02.463.425.280'], ['F02.463.425.540'], ['B01.050.150.900.649.313.992.635.505.700'], ['D02.145.074.722.822.775', 'D03.132.760.180.848', 'D03.132.889.601.775', 'D03.605.084.500.722.822.775', 'D03.605.869.822.775']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Auditory evoked potentials compared with bispectral index for monitoring of midazolam and propofol sedation during colonoscopy. | OBJECTIVES: The purpose of this study was to evaluate and compare Bispectral index (BIS) and A-line auditory evoked potential index (AAI) for monitoring depth of low-dose midazolam and propofol sedation during colonoscopy.METHODS: A total of 115 consecutive patients (ASA I-IV), receiving low-dose midazolam and propofol... | ['Adult', 'Aged', 'Aged, 80 and over', 'Awareness', 'Colonoscopy', 'Conscious Sedation', 'Consciousness', 'Electroencephalography', 'Evoked Potentials, Auditory', 'Female', 'Humans', 'Hypnotics and Sedatives', 'Male', 'Midazolam', 'Middle Aged', 'Monitoring, Intraoperative', 'Propofol', 'Prospective Studies', 'Young Ad... | 19,190,608 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F02.463.188.150'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['E03.250'], ['F02.463.188.409', 'F02.830.233'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500.370', 'G07.888.250... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Consecutive Inhibition of ISG15 Expression and ISGylation by Cytomegalovirus Regulators. | Interferon-stimulated gene 15 (ISG15) encodes an ubiquitin-like protein that covalently conjugates protein. Protein modification by ISG15 (ISGylation) is known to inhibit the replication of many viruses. However, studies on the viral targets and viral strategies to regulate ISGylation-mediated antiviral responses are l... | ['Cell Line', 'Cytokines', 'Cytomegalovirus', 'Cytomegalovirus Infections', 'Fluorescent Antibody Technique', 'Gene Expression Regulation, Viral', 'Host-Parasite Interactions', 'Humans', 'Immunoblotting', 'Immunoprecipitation', 'Polymerase Chain Reaction', 'Transfection', 'Two-Hybrid System Techniques', 'Ubiquitins', '... | 27,564,865 | [['A11.251.210'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B04.280.382.150.150'], ['C01.925.256.466.245'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['G05.308.385'], ['G16.527.200.400'], ['B01.050.150.900.649.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vitro assessment of vancomycin HCl compatibility after coinfusion with a specialized amino acid formulation. | Vancomycin usage at British Columbia's Children's Hospital has increased substantially in the Special Care Nursery as a consequence of a study demonstrating a reduced morbidity and mortality in neonates with necrotizing enterocolitis when treated with vancomycin and cefotaxime. The inability to place more than one peri... | ['Amino Acids', 'Chromatography, High Pressure Liquid', 'Drug Stability', 'Humans', 'Hydrogen-Ion Concentration', 'In Vitro Techniques', 'Infant, Newborn', 'Infusions, Intravenous', 'Parenteral Nutrition', 'Vancomycin'] | 1,942,466 | [['D12.125'], ['E05.196.181.400.300'], ['E05.916.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E05.481'], ['M01.060.703.520'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['E02.421.505', 'E02.642.500.505'], ['D09.400.420.925', 'D12.644.233.925']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Quantitative cell-free circulating BRAFV600E mutation analysis by use of droplet digital PCR in the follow-up of patients with melanoma being treated with BRAF inhibitors. | BACKGROUND: Around 50% of cutaneous melanomas harbor the BRAF(V600E) mutation and can be treated with BRAF inhibitors. DNA carrying this mutation can be released into circulation as cell-free BRAF(V600E) (cfBRAF(V600E)). Droplet digital PCR (ddPCR) is an analytically sensitive technique for quantifying small concentrat... | ['Antineoplastic Agents', 'DNA', 'DNA Mutational Analysis', 'Disease-Free Survival', 'Female', 'Follow-Up Studies', 'Humans', 'Imidazoles', 'Indoles', 'Kaplan-Meier Estimate', 'Male', 'Melanoma', 'Middle Aged', 'Mutation', 'Oximes', 'Polymerase Chain Reaction', 'Proto-Oncogene Proteins B-raf', 'Sulfonamides', 'Treatmen... | 25,411,185 | [['D27.505.954.248'], ['D13.444.308'], ['E05.393.760.700.300'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Primary hepatic carcinoid with production of gastrin: a case report. | A case of small primary hepatic carcinoid is reported. The tumor was solid, and lower in echogenicity than the hepatic parenchyma on ultrasonography. It was homogeneously stained on enhanced computed tomography, and showed tumor blush without malignant neovascularity on hepatic arteriography. The tumor removed was 2.0 ... | ['Adult', 'Carcinoid Tumor', 'Diagnostic Imaging', 'Female', 'Gastrins', 'Humans', 'Liver', 'Liver Neoplasms'] | 8,372,237 | [['M01.060.116'], ['C04.557.465.625.650.200', 'C04.557.470.200.025.200', 'C04.557.580.625.650.200'], ['E01.370.350'], ['D06.472.317.413', 'D06.472.699.280', 'D12.644.400.320', 'D12.644.548.280', 'D12.776.631.650.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['C04.588.274.623', 'C06.301.623', 'C06... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sensory input enhances synaptogenesis of adult-born neurons. | The adult mammalian brain maintains a prominent stem cell niche in the subventricular zone supplying new neurons to the olfactory bulb. We examined the dynamics of synaptogenesis by imaging the formation and elimination of clusters of a postsynaptic marker (PSD95), genetically targeted to adult-born neurons. We imaged ... | ['Adult Stem Cells', 'Animals', 'Brain', 'Cell Differentiation', 'Cell Proliferation', 'Dendrites', 'Disks Large Homolog 4 Protein', 'Green Fluorescent Proteins', 'Guanylate Kinases', 'Intracellular Signaling Peptides and Proteins', 'Membrane Proteins', 'Mice', 'Mice, Inbred BALB C', 'Mice, Transgenic', 'Microscopy, Co... | 19,129,387 | [['A11.872.040'], ['B01.050'], ['A08.186.211'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['D08.811.913.696.650.450.750', 'D12.644.360.265', 'D12.776.476.265', 'D12.776.543.219', 'D12.776.631.224'], ['D12.776.532.265'], ['D08.811.913.696.650.450'], ['D12.644... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Calcium intake and osteoporosis]. | It has been well known that calcium (Ca) deficiency is a major risk factor for osteoporosis. However, few reliable evidences were available regarding the beneficial effect of increased dietary Ca in osteoporosis. Meta-analysis of the recently reported randomized clinical trials revealed that the beneficial effect of in... | ['Calcium, Dietary', 'Fractures, Bone', 'Humans', 'Osteoporosis', 'Randomized Controlled Trials as Topic'] | 15,577,166 | [['D01.146.395'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.198.579', 'C18.452.104.579'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pond4Kids - an multi-site online Pediatric Oncology Research Database for collaborative protocol research. | Abstract: The Pediatric Oncology Networked Database (POND4Kids) is an online, multilingual database for pediatric hematology/oncology patients. Its purpose is to improve the care of pediatric oncology patients in countries with limited resources by the exchange of information and experience between oncologists in diver... | ['Child', 'Cooperative Behavior', 'Databases, Factual', 'Humans', 'Medical Oncology', 'Medical Records Systems, Computerized', 'Online Systems', 'Pediatrics', 'Systems Integration'] | 16,779,377 | [['M01.060.406'], ['F01.145.813.115'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.429.515'], ['E05.318.308.940.968.625', 'L01.313.500.750.300.695', 'N04.452.859.564.650', 'N05.715.360.300.715.500.530', 'N06.850.520.308.940.968.625'], ['L01.313.500.750.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Reactions of papain and of low-molecular-weight thiols with some aromatic disulphides. 2,2'-Dipyridyl disulphide as a convenient active-site titrant for papain even in the presence of other thiols. | 1. The u.v.-spectral characteristics of 5,5'-dithiobis-(2-nitrobenzoic acid) (Nbs(2)), 2,2'-dipyridyl disulphide (2-Py-S-S-2-Py), 4,4'-dipyridyl disulphide (4-Py-S-S-4-Py), 5-mercapto-2-nitrobenzoic acid (Nbs), 2-thiopyridone (Py-2-SH) and 4-thiopyridone (Py-4-SH) were determined over a wide range of pH and used to cal... | ['Benzoates', 'Binding Sites', 'Cysteine', 'Disulfides', 'Hydrogen-Ion Concentration', 'Kinetics', 'Mathematics', 'Mercaptoethanol', 'Molecular Weight', 'Nitro Compounds', 'Papain', 'Protein Binding', 'Pyridines', 'Pyridones', 'Spectrophotometry, Ultraviolet', 'Structure-Activity Relationship', 'Time Factors'] | 4,721,623 | [['D02.241.223.100', 'D02.455.426.559.389.127'], ['G02.111.570.120'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['H01.548'], ['D02.033.375.534', 'D02.886.489.409'], ['G... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Supramolecular dioxygen receptors composed of an anionic water-soluble porphinatoiron(II) and cyclodextrin dimers. | Three types of per-O-methylated â-cyclodextrin dimers, Im2CD, Im3NHCD and Py3NHCD, were prepared as globin models. Im2CD was synthesized by the condensation reaction of mono(2(A)-amino)-per-O-methylated â-cyclodextrin with 3-(1H-imidazol-1-yl)pentanedioic acid. Im3NHCD and Py3NHCD were obtained through the S(N)2 reacti... | ['Coordination Complexes', 'Crystallography, X-Ray', 'Cyclodextrins', 'Dimerization', 'Hemeproteins', 'Imidazoles', 'Ligands', 'Metalloporphyrins', 'Models, Molecular', 'Molecular Structure', 'Oxidation-Reduction', 'Oxygen', 'Pyridines', 'Solubility', 'Spectrophotometry, Ultraviolet', 'Water'] | 22,041,783 | [['D01.234', 'D02.257'], ['E05.196.309.742.225'], ['D04.345.103', 'D09.301.915.400.375', 'D09.698.365.855.400.375'], ['G02.206', 'G03.230'], ['D12.776.422'], ['D03.383.129.308'], ['D27.720.470.480'], ['D02.257.250', 'D03.383.129.578.840.500.640', 'D03.633.400.909.500.640', 'D04.345.783.500.640', 'D23.767.727.640'], ['E... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of CCl4 metabolism by oxygen varies between isoenzymes of cytochrome P-450. | Oxygen inhibition of CCl4 metabolism by different isoenzymes of cytochrome P-450 was assessed by studying liver microsomes isolated from control rats and rats treated with phenobarbital or isoniazid. Rates of CCl4 metabolism were similar for all microsomes under a nitrogen atmosphere. An air atmosphere inhibited metabo... | ['Animals', 'Carbon Tetrachloride', 'Carbon Tetrachloride Poisoning', 'Cytochrome P-450 Enzyme System', 'Isoenzymes', 'Isoniazid', 'Male', 'Microsomes, Liver', 'Oxygen', 'Phenobarbital', 'Rats', 'Rats, Inbred Strains'] | 3,377,780 | [['B01.050'], ['D02.455.526.439.150'], ['C25.723.177'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D08.811.348', 'D12.776.800.300'], ['D02.442.436', 'D03.066.349.410', 'D03.383.725.394.582'], ['A11.284.835.540.541'], ['D01.268.185.550', 'D01.362.670'], ['D03.383.742.698.253.650'], ['B01.050.15... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Epithelial-mesenchymal transition events during human embryonic stem cell differentiation. | Epithelial-mesenchymal transition (EMT) occurs during embryonic development and may also be associated with the metastatic spread of epithelial tumors. During EMT, E-cadherin is down-regulated and this correlates with increased motility and invasion of cells. We show that differentiation of human embryonic stem (ES) ce... | ['Actins', 'Blotting, Western', 'Cadherins', 'Cell Differentiation', 'Cell Movement', 'Cells, Cultured', 'Cytoskeleton', 'Embryonic Stem Cells', 'Epithelium', 'Humans', 'Matrix Metalloproteinases', 'Membrane Glycoproteins', 'Mesoderm', 'Reverse Transcriptase Polymerase Chain Reaction', 'Snail Family Transcription Facto... | 18,056,451 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['G04.152'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['A11.284.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Solid-phase extraction of fluoxetine and norfluoxetine from serum with gas chromatography-electron-capture detection. | A rapid, selective, and sensitive method is described for the purification and analysis of fluoxetine and norfluoxetine using a solid-phase extraction column and gas chromatography-electron-capture detection. Linear quantitative response curves for fluoxetine and norfluoxetine are generated over a concentration range o... | ['Chromatography, Gas', 'Fluoxetine', 'Humans'] | 2,056,002 | [['E05.196.181.349'], ['D02.092.831.280'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ultrasonographic measurement of endometrial thickness during hormonal replacement therapy in postmenopausal women. | The objective of this study was to measure endometrial thickness by transvaginal ultrasonography during two regimens of hormonal replacement therapy (HRT) in postmenopausal women and to compare these data with endometrial histology. Transvaginal ultrasonographic evaluation of endometrial thickness and endometrial biops... | ['Biopsy, Needle', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Endometrium', 'Estradiol', 'Estrogen Replacement Therapy', 'Female', 'Humans', 'Medrogestone', 'Middle Aged', 'Postmenopause', 'Progesterone Congeners', 'Sensitivity and Specificity', 'Ultrasonography', 'Vagina'] | 9,644,774 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['A05.360.319.679.490'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis and biological evaluation of trehalose analogs as potential inhibitors of mycobacterial cell wall biosynthesis. | Analogs of trehalose are reported that were designed to interfere with mycolylation pathways in the mycobacterial cell wall. Several derivatives of 6,6'-dideoxytrehalose, including N,N'-dialkylamino and 6,6'-bis(sulfonamido) analogs, were prepared and evaluated for antimycobacterial activity against Mycobacterium tuber... | ['Antitubercular Agents', 'Cell Wall', 'Cord Factors', 'Microbial Sensitivity Tests', 'Mycobacterium tuberculosis', 'Sulfonamides'] | 11,814,442 | [['D27.505.954.122.085.255'], ['A11.284.183'], ['D10.390.240', 'D23.946.123.208'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['D02.065.884', 'D02.886.590.700']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Collagen polymorphism in the normal and diseased blood vessel wall. Investigation of collagens types I, III and V. | Estimation of collagens types I and III in pepsin digests and by analysis of specific cyanogen-bromide derived peptides by SDS-polyacrylamide gel electrophoresis, has indicated that both the undiseased human aortic media and the atherosclerotic plaque of the diseased intima contain more type I collagen than type III. T... | ['Adult', 'Aged', 'Animals', 'Aorta', 'Arteriosclerosis', 'Collagen', 'Cyanogen Bromide', 'Electrophoresis, Polyacrylamide Gel', 'Humans', 'Middle Aged', 'Swine'] | 7,082,417 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['A07.015.114.056'], ['C14.907.137.126'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D01.139.300.050.100', 'D01.625.175'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['B01.050.150.900.649.313.500.88... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Growing and developing Dictyostelium cells express different ras genes. | The expression of ras-related protein in the cellular slime mold Dictyostelium discoideum is developmentally regulated. It was previously reported that Dictyostelium possesses a single ras gene (Ddras) that is maximally expressed during the pseudoplasmodial stage of development. We have isolated a series of cDNA clones... | ['Amino Acid Sequence', 'Base Sequence', 'Cloning, Molecular', 'Dictyostelium', 'Fungal Proteins', 'Genes', 'Genes, Fungal', 'Genes, ras', 'Molecular Sequence Data', 'RNA, Messenger', 'Restriction Mapping', 'Transcription, Genetic', 'ras Proteins'] | 2,644,652 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['B01.046.550.200.300'], ['D12.776.354'], ['G05.360.340.024.340'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['G05.360.340.024.340.375.500.791.550'], ['L0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Hepatitis B prevention measures in chronic kidney disease patients]. | Hepatitis B virus infection is a major cause of morbidity and mortality among patients on dialysis, that are a target for vaccination. However, due to the poor immunogenicity of all types of vaccines in dialysis patients the collaboration between general practitioners, nephrologists and vaccination centers is essential... | ['Hepatitis B', 'Humans', 'Renal Dialysis', 'Renal Insufficiency, Chronic'] | 23,073,379 | [['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.300', 'E02.912.800'], ['C12.777.419.780.750', 'C13.351.968.419.780.750']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interhospital transfers by helicopter: the first 50 patients of the Careflight project. | An interhospital helicopter transfer service was set up using a dedicated helicopter fitted with medical equipment and staffed by anaesthetists. The system proved to be safe and practical. Fifty patients were referred from 38 hospitals throughout the UK, with 84% of transfers preplanned. Patients were transferred a mea... | ['Aircraft', 'Critical Illness', 'Hospitalization', 'Humans', 'Patient Transfer', 'Time Factors', 'Transportation of Patients', 'United Kingdom'] | 1,548,652 | [['J01.937.285.100'], ['C23.550.291.625'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.169.624', 'E02.760.400.630', 'N02.421.585.169.624', 'N02.421.585.400.630', 'N04.590.233.727.210.624'], ['G01.910.857'], ['E02.365.839', 'N02.421.297.879'], ['Z01.542.363']] | ['Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Variations of the circadian rhythm of cAMP in bronchial asthma after administration of fenoterol. | In the study of the physiology and therapeutic response of bronchial asthma the evaluation of adrenergic activity is of fundamental importance. References in the literature indicate a reduction of the intracellular concentration of cyclic AMP in asthmatic patients, as well as a reduction in the response to beta-adrener... | ['Adolescent', 'Adult', 'Asthma', 'Circadian Rhythm', 'Cyclic AMP', 'Ethanolamines', 'Female', 'Fenoterol', 'Humans', 'Male'] | 6,258,414 | [['M01.060.057'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['G07.180.562.190'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D02.033.100.291', 'D02.033.375.291', 'D02.092.063.291'], ['D02.033.100.291.465.300', 'D02.... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Stability of diagnosis of obsessive-compulsive disorder in the Epidemiologic Catchment Area study. | OBJECTIVE: This study examined the 1-year temporal stability of a National Institute of Mental Health Diagnostic Interview Schedule (DIS) lifetime diagnosis of obsessive-compulsive disorder in the Epidemiologic Catchment Area (ECA) study.METHOD: In that study, 20,862 individuals, aged 18 years and over, at five sites w... | ['Adolescent', 'Adult', 'Age Factors', 'Age of Onset', 'Catchment Area, Health', 'Comorbidity', 'Confidence Intervals', 'Data Collection', 'Educational Status', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Male', 'Mental Disorders', 'National Institute of Mental Health (U.S.)', 'Obsessive-Compulsive Disorder'... | 9,167,511 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['N01.224.791.200', 'N03.349.650.095', 'N06.850.505.400.800.200'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E05.318.308', 'L01.39... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Corticosteroid-induced leukocytosis in pregnancy: A prospective observational study. | BACKGROUND: In the course of managing preterm labour, increasing trends of total white cell count raises concern for the obstetrician, suggesting a possible underlying infectious aetiology. Although mild leukocytosis is expected in pregnancy, the patterns of increment after corticosteroid administration are not well de... | ['Adult', 'Dexamethasone', 'Female', 'Glucocorticoids', 'Humans', 'Leukocytosis', 'Obstetric Labor, Premature', 'Pregnancy', 'Prospective Studies', 'Young Adult'] | 29,197,879 | [['M01.060.116'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.378.553.475', 'C23.550.526'], ['C13.703.420.491'], ['G08.686.784.769'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Profiling hospitals for length of stay for treatment of psychiatric disorders. | Managed behavioral health care organizations (MBHOs) often profile hospitals on length of stay (LOS) and other performance measures. However, previous research has suggested that most of the variation in utilization for general medical conditions is attributable to case-mix indicators and random sources rather than ind... | ['Adolescent', 'Adult', 'Aged', 'Bipolar Disorder', 'Depressive Disorder', 'Diagnosis, Dual (Psychiatry)', 'Diagnosis-Related Groups', 'Female', 'Hospitals, Psychiatric', 'Humans', 'Length of Stay', 'Male', 'Managed Care Programs', 'Middle Aged', 'Pennsylvania', 'Schizophrenia', 'Substance-Related Disorders'] | 14,722,481 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F03.084.500'], ['F03.600.300'], ['E01.190'], ['N03.219.521.710.305.200.080'], ['N02.278.421.556.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['N03.219.521.576.343.800', 'N04.590.374.410'], ['M01.060.116.630'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Bypassing the rRNA processing endonucleolytic cleavage at site A2 in Saccharomyces cerevisiae. | Rrp5p is the only ribosomal RNA processing trans-acting factor that is required for the synthesis of both 18S and 5.8S rRNAs in Saccharomyces cerevisiae. Mutational analyses have characterized modified forms of Rrp5p that either affect formation of 18S rRNA by inhibiting cleavage at sites A0/A1/A2, or synthesis of 5.8S... | ['Fungal Proteins', 'Nuclear Proteins', 'Operon', 'RNA Precursors', 'RNA, Fungal', 'RNA, Ribosomal, 18S', 'RNA, Ribosomal, 5.8S', 'RNA-Binding Proteins', 'Ribosomes', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins'] | 11,105,750 | [['D12.776.354'], ['D12.776.660'], ['G05.360.340.024.686', 'G05.360.340.358.207.500'], ['D13.400.730', 'D13.444.735.640'], ['D13.444.735.500'], ['D13.444.735.686.675'], ['D13.444.735.686.660'], ['D12.776.157.725', 'D12.776.664.962'], ['A11.284.430.214.190.875.811'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s. | The conformationally coupled mechanism by which ATP is utilized by yeast Hsp90 is now well characterized. In contrast, ATP utilization by human Hsp90s is less well studied, and appears to operate differently. To resolve these conflicting models, we have conducted a side-by-side biochemical analysis in a series of mutan... | ['Adenosine Triphosphatases', 'Calorimetry', 'Cytoplasm', 'Dimerization', 'HSP90 Heat-Shock Proteins', 'Humans', 'Kinetics', 'Models, Molecular', 'Mutagenesis', 'Protein Conformation', 'Recombinant Proteins', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins'] | 19,032,597 | [['D08.811.277.040.025'], ['E05.196.131'], ['A11.284.430.214'], ['G02.206', 'G03.230'], ['D12.776.580.216.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['E05.599.595'], ['G05.558'], ['G02.111.570.820.709'], ['D12.776.828'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
NOTCH2 is neither rearranged nor mutated in t(1;19) positive oligodendrogliomas. | The combined deletion of 1p and 19q chromosomal arms is frequent in oligodendrogliomas (OD) and has recently been shown to be mediated by an unbalanced t(1;19) translocation. Recent studies of 1p/19q co-deleted OD suggest that the NOTCH2 gene is implicated in oligodendrocyte differentiation and may be involved in this ... | ['Base Sequence', 'Brain Neoplasms', 'Chromosomes, Human, Pair 1', 'Chromosomes, Human, Pair 19', 'DNA Mutational Analysis', 'Gene Rearrangement', 'Humans', 'Molecular Sequence Data', 'Mutation', 'Oligodendroglioma', 'Oligonucleotide Array Sequence Analysis', 'Receptor, Notch2', 'Translocation, Genetic'] | 19,119,320 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['A11.284.187.520.300.235.240', 'G05.360.162.520.300.235.240'], ['A11.284.187.520.300.460.465', 'G05.360.162.520.300.460.465'], ['E05.393.760.700.300'], ['G05.344'], ['B01.050.150.900.649.313.988.4... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
phs Locus of Escherichia coli, a mutation causing pleiotropic lesions in metabolism, is an rpoA allele. | The phs mutation, which causes a pleiotropic growth defect, has been mapped and shown to be an allele of rpoA, the gene for the alpha subunit of RNA polymerase. The mutation is shown to cause a transcription defect in the arabinose operon, araBAD. | ['Alleles', 'Arabinose', 'Bacteriophage lambda', 'Chromosome Mapping', 'Chromosomes, Bacterial', 'Coliphages', 'DNA-Directed RNA Polymerases', 'Escherichia coli', 'Genes, Bacterial', 'Genetic Complementation Test', 'Lysogeny', 'Mutation', 'Operon', 'Phenotype', 'Transcription, Genetic', 'Transduction, Genetic'] | 2,932,430 | [['G05.360.340.024.340.030'], ['D09.947.875.627.166'], ['B04.123.150.800.230', 'B04.123.205.230', 'B04.280.090.800.230'], ['E05.393.183'], ['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['B04.123.205'], ['D08.811.913.696.445.735.270'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.36... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cholesterol homeostasis in T cells. Methyl-beta-cyclodextrin treatment results in equal loss of cholesterol from Triton X-100 soluble and insoluble fractions. | Methyl-beta-cyclodextrin (MBCD) is frequently used to acutely deplete cells of cholesterol. A widespread assumption is that MBCD preferentially targets cholesterol in lipid rafts and that sensitivity to MBCD is proof of lipid raft involvement in a cellular process. To analyse any MBCD preference systematically, progres... | ['Cell Compartmentation', 'Cholesterol', 'Homeostasis', 'Humans', 'Jurkat Cells', 'Octoxynol', 'Solubility', 'Surface-Active Agents', 'T-Lymphocytes', 'Temperature', 'beta-Cyclodextrins'] | 18,373,974 | [['G04.128'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['G07.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.495', 'A11.251.860.180.495', 'A15.382.490.555.567.569.440'], ['D02.033.455.250.700.660', 'D05.750.741.610', 'D25.720.741.610', 'J01.637.051.720.741.610... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
FUS-DDIT3 prevents the development of adipocytic precursors in liposarcoma by repressing PPARgamma and C/EBPalpha and activating eIF4E. | BACKGROUND: FUS-DDIT3 is a chimeric protein generated by the most common chromosomal translocation t(12;16)(q13;p11) linked to liposarcomas, which are characterized by the accumulation of early adipocytic precursors. Current studies indicate that FUS-DDIT3- liposarcoma develops from uncommitted progenitors. However, th... | ['Adipocytes', 'Animals', 'CCAAT-Enhancer-Binding Protein-alpha', 'Cell Line', 'Eukaryotic Initiation Factor-4E', 'Humans', 'Liposarcoma', 'Mice', 'Mice, Transgenic', 'Mutant Chimeric Proteins', 'Oncogene Proteins, Fusion', 'PPAR gamma', 'Stem Cells', 'Up-Regulation'] | 18,596,980 | [['A11.329.114'], ['B01.050'], ['D12.776.260.108.124.500', 'D12.776.660.167.500', 'D12.776.930.127.124.500'], ['A11.251.210'], ['D12.776.157.725.750.374', 'D12.776.835.725.868.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.550.420', 'C04.557.450.795.465'], ['B01.050.150.900.649.313.992.635.50... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reported infections after human tissue transplantation before and after new Food and Drug Administration (FDA) regulations, United States, 2001 through June, 2010. | Processors distributed about 1.5 million human tissue allografts in the U.S. in 2007. The potential for transmitting infections through allografts concerns clinicians and patients. In 2005, FDA implemented Current Good Tissue Practice (CGTP) rules requiring tissue establishments to report to FDA certain serious infecti... | ['Death', 'Hospitalization', 'Humans', 'Infections', 'Research Report', 'Social Control, Formal', 'Time Factors', 'Transplantation, Homologous', 'Transplants', 'United States', 'United States Food and Drug Administration'] | 21,479,712 | [['C23.550.260'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01'], ['H01.770.644.864', 'L01.559.423.906.769'], ['I01.880.604', 'N03.706'], ['G01.910.857'], ['E04.936.864'], ['A01.941'], ['Z01.107.567.875'], ['I01.409.418.750.600.650.760', 'N03.540.348.500.500.600.650.760']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
Nonviability of cells with oxidative defects in galactose medium: a screening test for affected patient fibroblasts. | Diagnosis of respiratory chain defects in cultured skin fibroblasts is a difficult diagnostic procedure. We investigated the feasibility of using survival of skin fibroblasts in culture medium with galactose as the major carbon source as a method of quickly diagnosing cell lines that were compromised in oxidative metab... | ['Cell Line', 'Cell Survival', 'Cells, Cultured', 'Cytochrome-c Oxidase Deficiency', 'Fibroblasts', 'Galactose', 'Humans', 'Kearns-Sayre Syndrome', 'MELAS Syndrome', 'Mitochondria', 'Optic Atrophies, Hereditary', 'Pyruvate Decarboxylase', 'Pyruvate Dehydrogenase Complex', 'Pyruvate Dehydrogenase Complex Deficiency Dise... | 1,329,873 | [['A11.251.210'], ['G04.346'], ['A11.251'], ['C16.320.565.240', 'C18.452.660.195'], ['A11.329.228'], ['D09.947.875.359.377'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.651.460.700.500', 'C10.292.562.750.250.500', 'C10.597.622.447.511.500', 'C10.668.491.500.700.500', 'C11.590.472.250.500', 'C11.768.585.658.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Forensic dental and medical response to the Bali bombing. A personal perspective. | After the Bali bombing on 12 October 2002, once the survivors had been treated or evacuated, many dead, severely burned and fragmented bodies were left. Formal identification was required before any remains could be released to grieving families. Australia sent a team to assist the Indonesians in this daunting and dist... | ['Australia', 'Forensic Dentistry', 'Forensic Medicine', 'Humans', 'Indonesia', 'International Cooperation', 'Terrorism'] | 14,503,901 | [['Z01.639.100', 'Z01.678.100.373'], ['H02.163.285', 'I01.198.780.875'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.145.380', 'Z01.639.580'], ['I01.615.500'], ['I01.198.240.856.800', 'I01.880.735.900.800']] | ['Geographicals [Z]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 |
Prostaglandin accumulation by isolated uterine endometrical epithelial cells from six-day pregnant rabbits. | Endometrial epithelial cell plaques were enzymatically isolated from rabbit uteri 6 days after artificial insemination. These cells were judged viable by exclusion of [3H]mannitol, trypan blue and [57Co]EDTA, and contained receptors for the ligand, [3H]quinuclidinyl benzilate (QNB). The cell plaques were evaluated for ... | ['Animals', 'Endometrium', 'Epithelium', 'Female', 'Hydrogen-Ion Concentration', 'Pregnancy', 'Pregnancy, Animal', 'Prostaglandins', 'Quinuclidinyl Benzilate', 'Rabbits', 'Temperature', 'Time Factors'] | 6,652,186 | [['B01.050'], ['A05.360.319.679.490'], ['A10.272'], ['G02.300'], ['G08.686.784.769'], ['G08.686.784.769.498'], ['D10.251.355.255.550', 'D23.469.050.175.725'], ['D02.241.223.601.238.306.740', 'D02.241.511.085.740', 'D03.605.687.800'], ['B01.050.150.900.649.313.968.700'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.5... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A protease inhibitor, NCO-700, improves the contractile function in stunned canine myocardium. | To explore the role of calcium-dependent protease in the stunned myocardium, open-chest dogs underwent 15 min of left anterior descending coronary artery occlusion followed by 2 h of reperfusion. Dogs received a single bolus intravenous injection of either the protease inhibitor NCO-700 (n = 6) or saline (n = 6) 1 min ... | ['Animals', 'Dogs', 'Hemodynamics', 'Injections, Intravenous', 'Myocardial Contraction', 'Myocardial Stunning', 'Piperazines', 'Protease Inhibitors'] | 7,967,015 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['G09.330.380'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['G09.330.580', 'G11.427.494.570'], ['C14.280.671', 'C23.888.582'], ['D03.383.606'], ['D27.505.519.389.745']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serotonin 5-HT1A and 5-HT3 receptors in an impulsive-aggressive phenotype. | In adult male hamsters, individual differences in offensive aggression are correlated with differences in impulsive choice and decreased serotonin (5-HT) innervation. As serotonin 1A (5-HT1A) receptors participate in the inhibition of aggression, whereas 5-HT3 receptor activation facilitates aggression, the authors hyp... | ['Aggression', 'Analysis of Variance', 'Animals', 'Brain', 'Conditioning, Psychological', 'Cricetinae', 'Fluoxetine', 'Immunohistochemistry', 'Impulsive Behavior', 'Male', 'Mesocricetus', 'Phenotype', 'Photomicrography', 'Receptor, Serotonin, 5-HT1A', 'Receptors, Serotonin, 5-HT3', 'Reward', 'Serotonin', 'Serotonin Upt... | 19,485,565 | [['F01.145.126.125', 'F01.145.813.045'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A08.186.211'], ['F02.463.425.179'], ['B01.050.150.900.649.313.992.635.075.250'], ['D02.092.831.280'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The regulation of miRNAs by reconstituted high-density lipoproteins in diabetes-impaired angiogenesis. | Diabetic vascular complications are associated with impaired ischaemia-driven angiogenesis. We recently found that reconstituted high-density lipoproteins (rHDL) rescue diabetes-impaired angiogenesis. microRNAs (miRNAs) regulate angiogenesis and are transported within HDL to sites of injury/repair. The role of miRNAs i... | ['Animals', 'Cell Line', 'Diabetes Mellitus, Experimental', 'Diabetic Angiopathies', 'Humans', 'Lipoproteins, HDL', 'Male', 'Mice', 'MicroRNAs', 'Neovascularization, Physiologic'] | 30,206,364 | [['B01.050'], ['A11.251.210'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C14.907.320', 'C19.246.099.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.532.432', 'D12.776.521.479'], ['B01.050.150.900.649.313.992.635.505.500'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Eccrine syringofibroadenomatosis in two patients with bullous pemphigoid. | A 67-year-old man and an 84-year-old woman developed palmoplantar erythema following resolution of bullous pemphigoid (BP). Clinical manifestations of the palmoplantar lesions in these 2 patients ranged from prominent, well-demarcated erythematous areas with focal erosions and fissures to mild erythema. On histological... | ['Actin Cytoskeleton', 'Adenoma, Sweat Gland', 'Aged', 'Aged, 80 and over', 'Basement Membrane', 'Cell Division', 'Cell Nucleus', 'Cytoplasm', 'Desmosomes', 'Eccrine Glands', 'Epidermis', 'Erythema', 'Female', 'Fibroadenoma', 'Foot Diseases', 'Hand', 'Humans', 'Male', 'Microscopy, Electron', 'Microvilli', 'Pemphigoid, ... | 9,529,566 | [['A11.284.430.214.190.750.050'], ['C04.557.470.035.175', 'C04.557.470.550.175'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A10.272.220', 'A10.615.179'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.214'], ['A11.284.149... | ['Anatomy [A]', 'Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Treatment of patients with arterial hypertension and other stroke risk factors in clinical practice. The PROGNOS program]. | AIM: To analyse recent data on the treatment of arterial hypertension (AH) with other risk factors (RF) of cerebral stroke in the Russian Federation, assessment of effects of antihypertensive treatment with a combined drug Hyzaar on the risk of cardiovascular complications (including cerebral stroke), on affection of t... | ['Aged', 'Drug Combinations', 'Female', 'Humans', 'Hydrochlorothiazide', 'Hypertension', 'Losartan', 'Male', 'Middle Aged', 'Risk Factors', 'Stroke'] | 19,827,647 | [['M01.060.116.100'], ['D26.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.590.700.135.261.476', 'D02.886.655.500.261.476', 'D03.633.100.174.261.476'], ['C14.907.489'], ['D02.455.426.559.389.185.475', 'D03.383.129.308.507', 'D03.383.129.617.467'], ['M01.060.116.630'], ['E05.318.740.600.800.725', 'N05... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Analysing eucalypt expansion in Portugal as a fire-regime modifier. | Eucalypts, especially blue gum (Eucalyptus globulus), have been extensively planted in Portugal and nowadays dominate most of its forest landscapes. Large-scale forestation programs can intensify fire activity, and blue gum plantations are often viewed as highly flammable due to the nature and structure of the fuel com... | ['Environmental Monitoring', 'Eucalyptus', 'Forestry', 'Forests', 'Portugal', 'Wildfires'] | 30,797,129 | [['N06.850.460.350.080', 'N06.850.780.375'], ['B01.650.940.800.575.912.250.773.366'], ['J01.576.430'], ['G16.500.275.157.437', 'N06.230.124.343'], ['Z01.542.727'], ['G01.311.988', 'N06.230.100.230.925', 'N06.230.216.875']] | ['Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Biliary stenting for unresectable cholangiocarcinoma: A population-based study of long-term outcomes and hospital costs in Taiwan. | Few studies have compared percutaneous biliary stenting (PBS) and endoscopic biliary stenting (EBS) in terms of long-term effects on cholangiocarcinoma (CC), and few have systematically evaluated outcome associations in Taiwan. This study aimed to compare long-term outcomes between two treatments for unresectable CC: P... | ['Aged', 'Bile Ducts, Intrahepatic', 'Cholangiocarcinoma', 'Endoscopy', 'Female', 'Hospital Costs', 'Humans', 'Length of Stay', 'Linear Models', 'Male', 'Middle Aged', 'Propensity Score', 'Proportional Hazards Models', 'Stents', 'Survival Analysis', 'Taiwan', 'Time Factors', 'Treatment Outcome'] | 26,162,818 | [['M01.060.116.100'], ['A03.159.183.158', 'A03.620.150'], ['C04.557.470.200.025.450'], ['E01.370.388.250', 'E04.502.250'], ['N03.219.151.400.687', 'N03.219.262.500', 'N05.300.375.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['E05.318.740.500.500', 'E05.318.740.750.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Evaluation of a "walk-through" ladder top design during ladder-roof transitioning tasks. | This study evaluated the effect of an extension ladder "walk-through" top design on kinetic and kinematic behaviors and the outward destabilizing forces induced on the ladder during transitioning at elevation. Thirty-two male participants performed stepping tasks between a ladder top and a roof at simulated elevation i... | ['Accidental Falls', 'Adult', 'Biomechanical Phenomena', 'Computer Simulation', 'Equipment Design', 'Friction', 'Humans', 'Male', 'Middle Aged', 'Safety', 'Task Performance and Analysis', 'User-Computer Interface', 'Walking', 'Young Adult'] | 27,890,159 | [['N06.850.135.122'], ['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['L01.224.160'], ['E05.320'], ['G01.374.618'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N06.850.135.060.075'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600'], ['L01.224.900.910'], ['G11.427.410.568.900', 'G11.42... | ['Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
[Doctor or technician? Reflections on the medical professional today]. | Medicine is an outstanding example of an empirical science in theory and practice. In every stage of his work a doctor should be ready to pick up signs of possible scientific progress. Being constantly attentive and able to see anything new occurring, however difficult it may be to discern, should remain the basis of a... | ['Clinical Medicine', 'Physicians'] | 18,034,410 | [['H02.403.200'], ['M01.526.485.810', 'N02.360.810']] | ['Disciplines and Occupations [H]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Should liquid-based cytology be repeated at the time of colposcopy? | OBJECTIVE: To evaluate the usefulness of repeated liquid cytology at the time of colposcopy.MATERIALS AND METHODS: We screened 5,100 women with liquid-based cytology and human papillomavirus (HPV) DNA testing. Women with any abnormal cytology result including atypical squamous cells of undetermined significance (ASCUS)... | ['Adolescent', 'Adult', 'Colposcopy', 'Cytodiagnosis', 'DNA, Viral', 'Female', 'Humans', 'Mass Screening', 'Middle Aged', 'Papillomaviridae', 'Sensitivity and Specificity', 'Uterine Cervical Neoplasms'] | 15,870,528 | [['M01.060.057'], ['M01.060.116'], ['E01.370.378.150', 'E01.370.388.250.150', 'E04.502.250.150', 'E04.520.150', 'E04.950.300.210'], ['E01.370.225.500.384', 'E05.200.500.384', 'E05.242.384'], ['D13.444.308.568'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Desensitization to a whole egg by rush oral immunotherapy improves the quality of life of guardians: A multicenter, randomized, parallel-group, delayed-start design study. | BACKGROUND: Patients with food allergies and their families have a significantly reduced health-related quality of life (QOL).METHODS: We performed a multicenter, randomized, parallel-group, delayed-start design study to clarify the efficacy and safety of rush oral immunotherapy (rOIT) and its impact on the participant... | ['Administration, Oral', 'Adolescent', 'Caregivers', 'Child', 'Child, Preschool', 'Desensitization, Immunologic', 'Egg Hypersensitivity', 'Egg White', 'Female', 'Humans', 'Male', 'Quality of Life', 'Treatment Outcome'] | 28,778,455 | [['E02.319.267.100'], ['M01.060.057'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['M01.060.406'], ['M01.060.406.448'], ['E02.095.465.425.450.310', 'E05.478.610.310'], ['C20.543.480.370.150'], ['G07.203.300.470.700', 'J02.500.470.700'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.800', 'K01.752.400.750',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
[Molecular targeted cancer therapy and genetic tests --chairman's introductory remarks]. | Genetic tests for individualized cancer therapy are now expanding their repertoire as pharmacogenomics biomarkers, coupled with advances in molecular targeted therapy. These tests were considered special in the 1990s, because they were almost entirely limited to hematopoietic tumors and other rare tumors. Molecular tar... | ['Biomarkers, Tumor', 'Genetic Testing', 'Humans', 'Molecular Targeted Therapy', 'Neoplasms'] | 23,323,461 | [['D23.101.140'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.574'], ['C04']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Clinical features of IgG4-related dacryoadenitis. | BACKGROUND: To elucidate the clinical characteristics of IgG4-related dacryoadenitis.METHODS: Clinical features, laboratory findings, radiological findings, associated diseases, treatment, and prognosis were prospectively examined in 12 patients (seven men, five women; mean age, 60.9 ± 15.1 years) with IgG4-related dac... | ['Adult', 'Aged', 'Autoimmune Diseases', 'Corneal Diseases', 'Dacryocystitis', 'Diplopia', 'Eye Diseases', 'Eyelid Diseases', 'Female', 'Glucocorticoids', 'Humans', 'Immunoglobulin G', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Ocular Motility Disorders', 'Oculomotor Muscles', 'Optic Neuritis', 'Prospective ... | 24,318,531 | [['M01.060.116'], ['M01.060.116.100'], ['C20.111'], ['C11.204'], ['C11.496.221'], ['C10.597.751.941.339', 'C11.966.339', 'C23.888.592.763.941.339'], ['C11'], ['C11.338'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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