Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peripheral clocks and the regulation of cardiovascular and metabolic function. | Circadian rhythms generated by cell autonomous biological clocks allow for the appropriate temporal synchronization of physiology and behavior, optimizing the efficiency of biological systems. Circadian oscillators and functions have been uncovered in both central and peripheral tissues. This article describes methodol... | ['ARNTL Transcription Factors', 'Animals', 'Aorta, Thoracic', 'Basic Helix-Loop-Helix Transcription Factors', 'Biological Clocks', 'Blood Glucose', 'Blood Pressure', 'Cardiovascular Physiological Phenomena', 'Chromatin Immunoprecipitation', 'Circadian Rhythm', 'Diabetes Mellitus', 'Glucose Tolerance Test', 'Insulin', '... | 15,817,310 | [['D12.644.360.138.049', 'D12.776.260.103.249', 'D12.776.476.156.100', 'D12.776.930.125.249'], ['B01.050'], ['A07.015.114.056.372'], ['D12.776.260.103', 'D12.776.930.125'], ['G07.180.562.094'], ['D09.947.875.359.448.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.330'], ['E05.393.170', 'E05.478.605.160'], ['G0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sexually transmitted pathogens in pregnant women in a rural South African community. | One hundred and ninety three consecutive pregnant women attending peripheral antenatal clinics attached to Ngwelezana Hospital, Empangeni, Kwa-Zulu, were examined for evidence of sexually transmitted pathogens. The following incidences were found: Trichomonas vaginalis 49.2% (95), Candida spp 38.3% (74), Chlamydia trac... | ['Adolescent', 'Adult', 'Female', 'Humans', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Rural Health', 'Sexually Transmitted Diseases', 'South Africa'] | 2,807,289 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['C01.674', 'C13.703.700'], ['N01.400.548.750'], ['C01.221.812', 'C01.778', 'C12.294.668', 'C13.351.500.711', 'C23.550.291.531.937'], ['Z01.058.290.175.735']] | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Early care of acute myocardial infarction. | A fixed life support station (LSS) was established in the emergency department of a community hospital in order to provide early care for patients with suspected acute myocardial infarction (MI). Prospective studies were conducted on 154 patients with verified acute MI. Median time from onset of symptoms to electrocard... | ['Acute Disease', 'Adult', 'Age Factors', 'Aged', 'Arrhythmias, Cardiac', 'Coronary Care Units', 'Critical Care', 'Heart Failure', 'Humans', 'Life Support Systems', 'Myocardial Infarction', 'New York', 'Shock, Cardiogenic'] | 962,455 | [['C23.550.291.125'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C14.280.067', 'C23.550.073'], ['N02.278.388.493.211'], ['E02.760.190', 'N02.421.585.190'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.230.150.391'], ['C14.280.647.500', 'C14.907.585.500', '... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Adenosine Monophosphate Binding Stabilizes the KTN Domain of the Shewanella denitrificans Kef Potassium Efflux System. | Ligand binding is one of the most fundamental properties of proteins. Ligand functions fall into three basic types: substrates, regulatory molecules, and cofactors essential to protein stability, reactivity, or enzyme-substrate complex formation. The regulation of potassium ion movement in bacteria is predominantly und... | ['Adenosine Monophosphate', 'Potassium-Hydrogen Antiporters', 'Protein Binding', 'Protein Domains', 'Protein Folding', 'Protein Multimerization', 'Protein Stability', 'Protein Structure, Quaternary', 'Shewanella'] | 28,656,748 | [['D03.633.100.759.646.138.180', 'D13.695.667.138.180', 'D13.695.827.068.180'], ['D12.776.157.530.450.162.276', 'D12.776.543.550.190.442', 'D12.776.543.585.450.162.276'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.275.750', 'G02.111.570.820.709.610.500'], ['G01.154.651', 'G02.111.688'], ['G02.111.694'], ['G02.11... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bad drivers: identification of a target group for alcohol-related prevention and early intervention. | Individuals arrested for driving while intoxicated (DWI) have been targeted for preventive intervention of alcohol-related problems. However, high rates of diagnosed alcoholism among DWI arrestees suggest a need to identify individuals at risk earlier in the developmental process. The present study investigates one suc... | ['Adult', 'Alcohol Drinking', 'Alcoholic Intoxication', 'Automobile Driving', 'Female', 'Humans', 'Male', 'Risk Factors'] | 2,308,351 | [['M01.060.116'], ['F01.145.317.269'], ['C25.775.100.175', 'F03.900.100.300'], ['I03.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Identification of canine saliva using mRNA-based assay. | A dog saliva analysis in addition to a bite-mark analysis may be important for evidence when a crime involves a dog bite. In this study, the utility of detecting canine saliva-specific mRNAs to identify canine saliva was evaluated. Canine saliva swabs (n = 20), urine swabs (n = 20), body surface swabs (n = 20), whole b... | ['Animals', 'Carbonic Anhydrases', 'Dogs', 'Genetic Markers', 'Glyceraldehyde-3-Phosphate Dehydrogenases', 'Humans', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'Saliva', 'Salivary Proteins and Peptides'] | 27,225,391 | [['B01.050'], ['D08.811.520.241.300.150'], ['B01.050.150.900.649.313.750.250.216.200'], ['D23.101.387', 'G05.695.450'], ['D08.811.682.657.163.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.444.735.544'], ['E05.393.620.500.706'], ['A12.200.666'], ['D12.644.848', 'D12.776.850']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recurrent condylomata acuminata treated with recombinant interferon alpha-2a. A multicenter double-blind placebo-controlled clinical trial. Condylomata International Collaborative Study Group. | A randomized, double-blind, placebo-controlled, international multicenter trial was conducted, using 1.5 MIU subcutaneous interferon alpha-2a 3 times a week for 4 weeks in 170 patients (interferon, n = 125 or placebo, n = 45) with condylomata acuminata who had failed to respond to standard therapies. There was no diffe... | ['Adolescent', 'Adult', 'Aged', 'Anus Diseases', 'Condylomata Acuminata', 'Double-Blind Method', 'Female', 'Genital Diseases, Female', 'Genital Diseases, Male', 'Humans', 'Interferon alpha-2', 'Interferon-alpha', 'Male', 'Middle Aged', 'Recombinant Proteins', 'Recurrence'] | 8,105,627 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C06.405.469.860.101'], ['C01.221.812.640.220', 'C01.778.640.220', 'C01.925.256.650.810.217', 'C01.925.813.220', 'C01.925.825.810.110', 'C01.925.928.914.217', 'C17.800.838.790.810.110'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.4... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Economic burden of gastro-oesophageal reflux disease and dyspepsia: A community-based study. | BACKGROUND AND STUDY AIMS: Gastro-oesophageal reflux disease (GERD) and dyspepsia are common digestive disorders that inflict serious harm, burden and economic consequences on individuals worldwide. The aim of this study was to estimate the direct and indirect economic burden of GERD and dyspepsia in the whole populati... | ['Adult', 'Aged', 'Cost of Illness', 'Dyspepsia', 'Efficiency', 'Gastroesophageal Reflux', 'Health Care Costs', 'Hospitalization', 'Humans', 'Iran', 'Male', 'Middle Aged', 'Office Visits', 'Prevalence', 'Surveys and Questionnaires'] | 21,684,479 | [['M01.060.116'], ['M01.060.116.100'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['C23.888.821.236'], ['F02.784.692.351', 'N04.452.209'], ['C06.405.117.119.500.484'], ['N03.219.151.400', 'N05.300.375'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.40... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Green Hydroselenation of Aryl Alkynes: Divinyl Selenides as a Precursor of Resveratrol. | A simple and efficient protocol to prepare divinyl selenides has been developed by the regio- and stereoselective addition of sodium selenide species to aryl alkynes. The nucleophilic species was generates in situ, from the reaction of elemental selenium with NaBH₄, utilizing PEG-400 as the solvent. Several divinyl sel... | ['Alkynes', 'Catalysis', 'Chemistry Techniques, Synthetic', 'Organoselenium Compounds', 'Resveratrol', 'Selenium', 'Stilbenes', 'Tellurium'] | 28,230,754 | [['D02.455.326.397'], ['G02.130'], ['E05.197', 'J01.897.836.249'], ['D02.731'], ['D02.455.426.559.389.150.700.725.875', 'D02.455.426.559.389.657.715.500'], ['D01.268.185.850', 'D01.578.700'], ['D02.455.426.559.389.150.700'], ['D01.268.185.950', 'D01.268.513.968']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Blunt bowel and mesenteric injury: diagnostic performance of CT signs. | PURPOSE: Our goal was to determine the sensitivity and specificity of various CT signs of blunt bowel and mesenteric injury.METHOD: The CT findings of 31 patients with blunt abdominal trauma were retrospectively assessed by three observers in consensus. All patients had laparotomy within 24 h of CT. The study group con... | ['Abdominal Injuries', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Air', 'Ascitic Fluid', 'Contrast Media', 'Contusions', 'Female', 'Hematoma', 'Humans', 'Intestines', 'Iothalamate Meglumine', 'Kidney', 'Laparotomy', 'Liver', 'Male', 'Mesentery', 'Middle Aged', 'Retrospective Studies', 'Rupture', 'Sensitivity ... | 9,294,556 | [['C26.017'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G16.500.275.063.150', 'N06.230.300.100.150'], ['A12.207.119'], ['D27.505.259.500', 'D27.720.259'], ['C26.974.250'], ['C23.550.414.838'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124'], ['D02.033.800.813.550... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Disseminated mycobacteriosis with M. kansasii in a case of AIDS without HIV infection]. | M. kansasii is an environmental Mycobacterium that causes disease mainly in patients with local or systemic immunodeficiency. We present a case with disseminated M. kansasii infection which led to a severe febrile illness lasting for 9 months. The patient had a combined acquired immunodeficiency syndrome (AIDS) which i... | ['AIDS-Related Opportunistic Infections', 'Antitubercular Agents', 'CD4 Lymphocyte Count', 'Combined Modality Therapy', 'Diagnosis, Differential', 'Drug Therapy, Combination', 'Female', 'Humans', 'Immunization, Passive', 'Lymphocyte Transfusion', 'Middle Aged', 'Mycobacterium Infections, Nontuberculous'] | 9,333,940 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['D27.505.954.122.085.255'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A fast and efficient segmentation scheme for cell microscopic image. | Microscopic cellular image segmentation schemes must be efficient for reliable analysis and fast to process huge quantity of images. Recent studies have focused on improving segmentation quality. Several segmentation schemes have good quality but processing time is too expensive to deal with a great number of images pe... | ['Algorithms', 'Artificial Intelligence', 'Color', 'Computational Biology', 'Cytodiagnosis', 'Image Processing, Computer-Assisted', 'Staining and Labeling'] | 17,531,140 | [['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['G01.590.540.199'], ['H01.158.273.180', 'L01.313.124'], ['E01.370.225.500.384', 'E05.200.500.384', 'E05.242.384'], ['L01.224.308'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.500.620.670', 'E05.200.750.600.670']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Description of the motor development of 3-12 month old infants with Down syndrome: the influence of the postural body position. | The purpose of the present study was to describe the rate of motor development in infants with Down syndrome in the age range of 3-12 months and identify the difficulties both in performance and acquiring motor skills in prone, supine, sitting and standing positions. Nineteen infants with Down syndrome and 25 healthy f... | ['Child Development', 'Down Syndrome', 'Humans', 'Infant', 'Longitudinal Studies', 'Motor Skills', 'Posture', 'Prone Position', 'Supine Position'] | 21,367,575 | [['F01.525.200', 'G07.345.374.750'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['F02.808.260'], ['G11.427.695'], ['G11.427.... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
What Sways People's Judgment of Sleep Quality? A Quantitative Choice-Making Study With Good and Poor Sleepers. | Study objectives: We conceptualized sleep quality judgment as a decision-making process and examined the relative importance of 17 parameters of sleep quality using a choice-based conjoint analysis.Methods: One hundred participants (50 good sleepers; 50 poor sleepers) were asked to choose between 2 written scenarios to... | ['Adolescent', 'Adult', 'Affect', 'Choice Behavior', 'Female', 'Humans', 'Judgment', 'Male', 'Reproducibility of Results', 'Self Report', 'Sleep', 'Sleep Initiation and Maintenance Disorders', 'Surveys and Questionnaires', 'Time Factors', 'Young Adult'] | 28,525,617 | [['M01.060.057'], ['M01.060.116'], ['F01.470.047'], ['F02.463.785.373.346'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.785.626'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.308.980.500', 'N05.715.360.300.800.500', 'N06.850.520.308.980.500'], ['F02.830.85... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Bayes' formula used for diagnosis of causalgia]. | 285 patients complain for pain in the oral mucosa. 92 patients characterized the pain as causalgia. The informations from the history taken were estimated by Bayes' formula. The results from this study showed there is possibility to be causalgia the pain in the oral mucosa characterized as burning, smarting or both of ... | ['Bayes Theorem', 'Burning Mouth Syndrome', 'Humans', 'Mouth Diseases', 'Mouth Mucosa'] | 2,640,743 | [['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['C07.465.114'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.465'], ['A10.615.550.599', 'A14.549.512']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Transcriptional regulation of human polyomavirus JC: evidence for a functional interaction between RelA (p65) and the Y-box-binding protein, YB-1. | The transcriptional control region of the human neurotropic polyomavirus JC virus contains a consensus NF-kappa B site which has been shown to enhance both basal and extracellular stimulus-induced levels of transcription of JC promoters. Here, we show that the expression of JC late promoter constructs containing the NF... | ['Base Sequence', 'Binding Sites', 'CCAAT-Enhancer-Binding Proteins', 'Chloramphenicol O-Acetyltransferase', 'Consensus Sequence', 'DNA-Binding Proteins', 'Gene Expression Regulation, Viral', 'Humans', 'JC Virus', 'Macromolecular Substances', 'Molecular Sequence Data', 'NF-kappa B', 'NFI Transcription Factors', 'Nuclea... | 8,709,216 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D12.776.260.108.124', 'D12.776.660.167', 'D12.776.930.127.124'], ['D08.811.913.050.134.170'], ['G02.111.570.580.175'], ['D12.776.260'], ['G05.308.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.280.210.700.615.400', 'B04.61... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[A technic for culturing bone cells]. | A technique of osseous cells culture has been perfected through discontinuous enzymatic digestion of young Mice prietal bones and using a chemically defined medium buffered by means of hepes. The cultural characteristics observed seem to correspond to those of osteogenic cells. | ['Animals', 'Cells, Cultured', 'Culture Media', 'Mice', 'Osteoclasts', 'Parietal Bone'] | 825,303 | [['B01.050'], ['A11.251'], ['D27.720.470.305', 'E07.206'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.329.372.700', 'A11.627.482.700'], ['A02.835.232.781.651']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Peritoneal dialysis in the nursing home. | UNLABELLED: The mean age of patients with end-stage renal disease increases steadily. The elderly on dialysis have significant comorbidity and require extra attention to meet their dialysis, dietary, and social needs, and some may need to be treated at a long-term care facility such as a nursing home (NH). Providing di... | ['Aged', 'Female', 'Humans', 'Male', 'Nursing Homes', 'Peritoneal Dialysis', 'Retrospective Studies'] | 20,174,996 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.825.610'], ['E02.870.300.650', 'E02.912.800.650'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825']] | ['Named Groups [M]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impacts of temperature on evolution of char structure during pyrolysis of lignin. | This study investigated the pyrolysis of lignin pyrolysis in a temperature region from 200 to 800 °C, aiming to understand influence of pyrolysis temperature on evolution of structures of the resulting char. The results showed that fusion of the ring structure initiated at 200 °C, where the C/H ratio in the char was eq... | ['Biofuels', 'Biomass', 'Charcoal', 'Hot Temperature', 'Lignin', 'Pyrolysis', 'Temperature'] | 31,677,466 | [['D20.147', 'N06.230.132.644.124'], ['G16.500.275.157.100', 'N06.230.124.100'], ['D01.268.150.150'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['D05.750.078.562.180.515', 'D05.750.078.687', 'D20.538', 'D25.720.099.687', 'J01... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Spatial Structure Can Decrease Symbiotic Cooperation. | Mutualisms occur when at least two species provide a net fitness benefit to each other. These types of interactions are ubiquitous in nature, with more being discovered regularly. Mutualisms are vital to humankind: Pollinators and soil microbes are critical in agriculture, bacterial microbiomes regulate our health, and... | ['Biological Evolution', 'Computer Simulation', 'Host-Parasite Interactions', 'Models, Biological', 'Spatial Analysis', 'Symbiosis'] | 30,681,912 | [['G05.045', 'G16.075'], ['L01.224.160'], ['G16.527.200.400'], ['E05.599.395'], ['E05.318.740.933', 'N05.715.360.750.746', 'N06.850.520.830.933'], ['G06.550.800', 'G16.840']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Description of the male, larva and nymphal stages of Cryptocellus iaci (Arachnida, Ricinulei), with an overview of tarsal sensilla and other integumental structures. | The male, larva and nymphal stages of Cryptocellus iaci Tourinho, Lo Man-Hung & Bonaldo, 2010, a species previously known only from a single female, are described based on specimens from around the type locality, in an area of both Terra Firme forest and igap? (flooded forests), at the Jufari River, Roraima State, Braz... | ['Animals', 'Arachnida', 'Body Size', 'Brazil', 'Female', 'Integumentary System', 'Larva', 'Male', 'Microscopy, Electron, Scanning', 'Nymph', 'Organ Size', 'Sensilla'] | 26,240,902 | [['B01.050'], ['B01.050.500.131.166'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['Z01.107.757.176'], ['A17'], ['B05.500.500', 'G07.345.500.550.500.500'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['B05.500.650', 'G07.345.500.550.500.650'], ['E01.370.600.115.100.660', '... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
[Vaccination against human papilloma virus and cervical cancer]. | The human papilloma virus family (HPV], mainly HPV 16, 18 but less HPV 31, 45 were proven to be the cause of cervical intraepithelial neoplasia and cancer. Following natural infection, only half of the infected women develop neutralizing antibodies and even these were of a very Low titer and found to be ineffective. He... | ['Cervical Intraepithelial Neoplasia', 'Female', 'Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18', 'Humans', 'Israel', 'Papillomaviridae', 'Papillomavirus Infections', 'Papillomavirus Vaccines', 'Uterine Cervical Neoplasms'] | 21,449,154 | [['C04.557.470.200.240.250'], ['D20.215.894.815.455', 'D20.215.894.899.498.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.375'], ['B04.280.210.655', 'B04.613.204.655'], ['C01.925.256.650', 'C01.925.928.725'], ['D20.215.894.899.498'], ['C04.588.945.418.948.850', 'C13.351.500.852.593.131', 'C13... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Pulmonary function in chronic renal failure patients managed by continuous ambulatory peritoneal dialysis. | The influence of intraperitoneal fluid on pulmonary function was studied in 20 unselected continuous ambulatory peritoneal dialysis (CAPD) patients, all but one of whom had at least one cardiorespiratory disorder. Measurements of pulmonary function were made with the abdomen empty and following the instillation of 2 1 ... | ['Adult', 'Aged', 'Diaphragm', 'Female', 'Humans', 'Hypertension', 'Kidney Failure, Chronic', 'Lung', 'Lung Diseases, Obstructive', 'Male', 'Methods', 'Middle Aged', 'Muscle Contraction', 'Peritoneal Dialysis, Continuous Ambulatory', 'Pressure'] | 3,459,092 | [['M01.060.116'], ['M01.060.116.100'], ['A02.633.567.900.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['A04.411'], ['C08.381.495'], ['E05.581'], ['M01.060.116.630'], ['G11.427.494'], ['E02.760.106.500', 'E02.870.300.650.500', 'E02.9... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
"Young women": the meaning of a collaborative program supporting young women's rehabilitation and reintegration into the labor market. | Women are at a higher risk for long-term sick leaves and mental ill health. The aim of this study was to explore a supportive program's meaning for women with anxiety/stress/depression problems that are unemployed and/or on a sick leave, and for the personnel involved. Seven women and the personnel (n = 5) were intervi... | ['Adult', 'Anxiety', 'Cooperative Behavior', 'Depression', 'Female', 'Follow-Up Studies', 'Humans', 'Program Evaluation', 'Qualitative Research', 'Return to Work', 'Sick Leave', 'Stress, Psychological', 'Sweden', 'Unemployment', 'Young Adult'] | 24,074,131 | [['M01.060.116'], ['F01.470.132'], ['F01.145.813.115'], ['F01.145.126.350'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['H01.770.644.241.850'], ['I03.946.449', 'N01.824.24... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
A virtual interface for interactions with 3D models of the human body. | The developed system is the first prototype of a virtual interface designed to avoid contact with the computer so that the surgeon is able to visualize 3D models of the patient's organs more effectively during surgical procedure or to use this in the pre-operative planning. The doctor will be able to rotate, to transla... | ['Computer Simulation', 'Human Body', 'Humans', 'Imaging, Three-Dimensional', 'User-Computer Interface'] | 19,377,116 | [['L01.224.160'], ['I01.076.201.450.560', 'K01.093.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['L01.224.900.910']] | ['Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
Dietary intake of the short-chain triglyceride triacetin vs. long-chain triglycerides decreases adipocyte diameter and fat deposition in rats. | Diets containing either triacetin (the water-soluble triglyceride of acetate) or long-chain triglycerides (LCT) were fed to rats for 30 d to determine the effect on body weight gain and adipose tissue cellularity. Male Sprague-Dawley rats were allowed free access to one of three diets: a control diet containing 5% of e... | ['Adipocytes', 'Animals', 'Body Composition', 'Body Weight', 'Cell Count', 'Dietary Fats', 'Lipid Metabolism', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Triacetin', 'Triglycerides'] | 7,738,686 | [['A11.329.114'], ['B01.050'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['G03.45... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Peroxisomal-proliferator-activated receptor alpha activates transcription of the rat hepatic malonyl-CoA decarboxylase gene: a key regulation of malonyl-CoA level. | MCD (malonyl-CoA decarboxylase), which catalyses decarboxylation of malonyl-CoA, is known to play an important role in the regulation of malonyl-CoA concentration. Recently, it has been observed that the expression of MCD is significantly decreased in the hearts of the PPARalpha (peroxisome-proliferator-activated recep... | ['Animals', 'Base Sequence', 'Binding Sites', 'Carboxy-Lyases', 'Cell Line', 'Cell Line, Tumor', 'Fenofibrate', 'Gene Expression Regulation, Enzymologic', 'Liver', 'Malonyl Coenzyme A', 'Molecular Sequence Data', 'Promoter Regions, Genetic', 'Pyrimidines', 'RNA, Messenger', 'Rats', 'Rats, Inbred OLETF', 'Receptors, Cyt... | 14,641,110 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D08.811.520.224.125'], ['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.241.081.114.968.500.625', 'D02.355.726.305.625', 'D02.455.426.559.389.134.750', 'D02.455.426.559.389.657.654.305.625', 'D02.522.223.750'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Bacterial Autoimmunity Due to a Restriction-Modification System. | Restriction-modification (RM) systems represent a minimal and ubiquitous biological system of self/non-self discrimination in prokaryotes [1], which protects hosts from exogenous DNA [2]. The mechanism is based on the balance between methyltransferase (M) and cognate restriction endonuclease (R). M tags endogenous DNA ... | ['Autoimmunity', 'Bacteriophages', 'DNA Repair', 'DNA Restriction-Modification Enzymes', 'Escherichia coli'] | 26,804,559 | [['G12.450.192'], ['B04.123'], ['G02.111.222', 'G05.219'], ['D08.811.150'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regression of pulmonary metastases from renal carcinoma. | This article describes a patient who had a nephrectomy and hormone therapy for renal carcinoma. There was roentgenographic evidence of pulmonary metastases at the time of surgery. He was alive and showed no clinical or roentgenographic evidence of pulmonary metastases six and one-half years after treatment. | ['Adenocarcinoma', 'Follow-Up Studies', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Metastasis', 'Neoplasm Regression, Spontaneous', 'Nephrectomy', 'Radiography', 'Testosterone', 'Time Factors'] | 1,258,244 | [['C04.557.470.200.025'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['C04.697.650', 'C23.550.727.650'], ['C04.697.670', 'C23.550.727.670', 'G16.76... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Superficial veins of the human spinal cord. An attempt at classification]. | By studying the systematization of superficial veins in 70 human spinal cords, it is possible to recognize three different systems: anterior, posterior and lateral. The anterior spinal venous system is formed by an antero-medial trunk extending from the filum terminale to the medulla oblongata, and by two antero-latera... | ['Collateral Circulation', 'Histological Techniques', 'Humans', 'Spinal Cord', 'Spinal Nerve Roots', 'Veins'] | 6,764,347 | [['G09.330.100.248'], ['E01.370.225.750', 'E05.200.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.186.854'], ['A08.800.800.720.725'], ['A07.015.908']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Understanding and predicting the diffusivity of organic compounds in polydimethylsiloxane material for passive sampler applications using a simple quantitative structure-property relationship model. | The diffusivity of 145 compounds in polydimethylsiloxane (PDMS) material was determined in the laboratory using a film stacking technique. The results were pooled with available literature data, providing a final data set of 198 compounds with diffusivity (DPDMS ) spanning over approximately 5 log units. The principal ... | ['Diffusion', 'Dimethylpolysiloxanes', 'Environmental Monitoring', 'Models, Theoretical', 'Normal Distribution', 'Quantitative Structure-Activity Relationship'] | 29,359,815 | [['G01.202', 'G02.196'], ['D02.756.650.700.150', 'D05.750.900.850.150', 'D25.720.900.850.150', 'J01.637.051.720.900.850.150'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E05.599'], ['E05.318.740.994.500', 'G17.820.500', 'N05.715.360.750.750.565', 'N06.850.520.830.994.500'], ['G02.111.830.500', 'G07.690.773.997.500']... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The sCEA molecule suppressive role in NK and TH1 cell functions in colorectal cancer. | The soluble form of carcinoembryonic antigen (sCEA), an oncofetal glycoprotein, is frequently produced by human epithelial-tumor cells, particularly of colorectal origin, and evaluated as a prognostic index of tumor progression and patient survival. sCEA molecules are often present at high concentrations in the periphe... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoembryonic Antigen', 'Colorectal Neoplasms', 'Female', 'Humans', 'Killer Cells, Natural', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Th1 Cells'] | 10,851,473 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.18... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Level dependent signal flow in the light pupil reflex. I. Latency of time domain responses to transient stimuli. | Latency of pupillary responses to light stimuli are smaller for larger steps of light, and larger for smaller steps of light (Alpern 1954; Lowenstein et al. 1964; Lee et al. 1969; Terdiman et al. 1969; Cibis et al. 1977; and many others). Miller and Thompson (1978), however, reported negligible change in pupil cycle ti... | ['Accommodation, Ocular', 'Cybernetics', 'Humans', 'Light', 'Models, Neurological', 'Photic Stimulation', 'Reflex, Pupillary', 'Time Factors'] | 8,452,891 | [['G14.010'], ['L01.906.099'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E05.599.395.642'], ['E05.723.729'], ['E01.370.376.550.650.690', 'E01.370.600.550.650.690', 'G11.561.731.705'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Complications of bioabsorbable orbital implants and fixation plates. | After orbital floor and trimalar fracture repair with the use of a bioabsorbable maxillofacial implant, a patient had eyelid retraction with a thickened, immobile eyelid. We observed a dense, fibrous scar and encapsulation at the implantation site. | ['Absorbable Implants', 'Biocompatible Materials', 'Bone Plates', 'Cicatrix', 'Eyelid Diseases', 'Humans', 'Internal Fixators', 'Lactic Acid', 'Male', 'Middle Aged', 'Orbital Fractures', 'Polyglycolic Acid', 'Polylactic Acid-Polyglycolic Acid Copolymer', 'Polymers'] | 14,752,321 | [['E07.695.025'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['C11.338'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.370', 'E07.858.442.660.460', 'E07.858.690.725... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Determination of batroxobin levels in the plasma of guinea pigs after epicutaneous and intravenous applications. | An enzyme immunoassay has been set up to measure batroxobin levels in plasma. This assay allowed the detection of amounts of batroxobin greater than 0.5 ng/ml plasma. After the epicutaneous application of 50 or 100 batroxobin units (BU)/kg body weight, no batroxobin could be detected in plasma samples taken 15, 30, 60,... | ['Animals', 'Batroxobin', 'Guinea Pigs', 'Immunoenzyme Techniques', 'Injections, Intravenous', 'Male', 'Serine Endopeptidases', 'Skin Absorption'] | 3,059,582 | [['B01.050'], ['D08.811.277.656.300.760.955.135', 'D08.811.277.656.959.350.955.135', 'D20.888.850.960.200.105', 'D23.946.833.850.960.200.105'], ['B01.050.150.900.649.313.992.550'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['D08.811.277.656.300.760', 'D08... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measurement of propranolol, 4-hydroxypropranolol and propranolol glycol in human plasma. | An HPLC method for the quantitative determination of propranolol, 4-hydroxypropranolol, and propranolol glycol in human plasma is described. The limits of sensitivity for the method were: 1 ng/ml propranolol; 5 ng/ml 4-hydroxypropranolol; and 1 ng/ml propranolol glycol. Data obtained from 6 healthy volunteers given a s... | ['Chromatography, High Pressure Liquid', 'Fluorometry', 'Glycols', 'Humans', 'Hydroxylation', 'Methods', 'Propranolol'] | 432,438 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison between linear and nonlinear in-season training programs in freshman football players. | The purpose of this study was to compare linear (LT) with nonlinear (NL) in-season training programs in freshman football players during the course of 2 separate seasons. During the first year (n = 14, mean +/- SD = 177.3 +/- 4.8 cm, 88.0 +/- 9.7 kg), the LT program was employed 2 days per week. In the second year (n =... | ['Adolescent', 'Analysis of Variance', 'Anthropometry', 'Football', 'Humans', 'Male', 'Physical Education and Training'] | 12,930,187 | [['M01.060.057'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['I03.450.642.845.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.233.543']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Clinical oxygen enhancement ratio of tumors in carbon ion radiotherapy: the influence of local oxygenation changes. | The effect of carbon ion radiotherapy on hypoxic tumors has recently been questioned because of low linear energy transfer (LET) values in the spread-out Bragg peak (SOBP). The aim of this study was to investigate the role of hypoxia and local oxygenation changes (LOCs) in fractionated carbon ion radiotherapy. Three-di... | ['Carbon', 'Cell Hypoxia', 'Cell Survival', 'Computer Simulation', 'Dose Fractionation, Radiation', 'Heavy Ion Radiotherapy', 'Heavy Ions', 'Linear Energy Transfer', 'Models, Biological', 'Models, Statistical', 'Neoplasms', 'Oxygen', 'Oxygen Consumption', 'Treatment Outcome'] | 24,728,013 | [['D01.268.150'], ['G03.197.300', 'G04.270.300'], ['G04.346'], ['L01.224.160'], ['E02.815.639.200'], ['E02.815.250'], ['G01.249.467'], ['G01.154.240.400', 'G02.111.255.400', 'G02.216.400'], ['E05.599.395'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['C04'], ['D01.268.185.550', 'D... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Alcohol-related attendances at an accident and emergency department. | Using a self-administered alcohol-related questionnaire and the clinical records a survey was made of the prevalence and severity of alcohol-related problems in the accident and emergency department at the Belfast City Hospital. Of 10,410 consecutive attendances during three months, 6,625 completed a questionnaire: 4,3... | ['Adolescent', 'Adult', 'Alcohol Drinking', 'Attitude to Health', 'Emergency Medical Services', 'Emergency Service, Hospital', 'Female', 'Humans', 'Male', 'Middle Aged', 'Northern Ireland', 'Prevalence', 'Surveys and Questionnaires', 'Wounds and Injuries'] | 8,516,977 | [['M01.060.057'], ['M01.060.116'], ['F01.145.317.269'], ['F01.100.150', 'N05.300.150'], ['N02.421.297'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.542.363.602'], ['E05.318.308.985.525.750', 'N01.224.935.597.750'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Translocation (3;8;8)(p22 or p23;p23;q12) in a case of pleomorphic adenoma: similarity to a primary cytogenetic abnormality detected in an endometrial adenocarcinoma. | Cytogenetic findings on the recurrence of a pleomorphic adenoma of the parotid gland are herein reported. The tumor showed an abnormal chromosome #8, which was very similar to a marker chromosome recently described as the sole abnormality in an endometrial adenocarcinoma. | ['Adenocarcinoma', 'Adenoma, Pleomorphic', 'Chromosome Banding', 'Chromosomes, Human, Pair 3', 'Chromosomes, Human, Pair 8', 'Female', 'Genetic Markers', 'Humans', 'Karyotyping', 'Male', 'Middle Aged', 'Parotid Neoplasms', 'Translocation, Genetic', 'Uterine Neoplasms'] | 3,034,396 | [['C04.557.470.200.025'], ['C04.557.435.090', 'C04.557.470.035.155'], ['E01.370.225.500.385.130', 'E01.370.225.500.620.670.130', 'E01.370.225.750.600.670.130', 'E05.200.500.385.130', 'E05.200.500.620.670.130', 'E05.200.750.600.670.130', 'E05.242.385.130', 'E05.393.285.130'], ['A11.284.187.520.300.235.250', 'G05.360.162... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mini-laparoscopic versus robotic radical hysterectomy plus systematic pelvic lymphadenectomy in early cervical cancer patients. A multi-institutional study. | OBJECTIVE: The aim of this study was to verify possible differences in terms of perioperative outcomes and complications between mini-laparoscopic radical hysterectomy with lymphadenectomy (mLRH) and robotic radical hysterectomy with lymphadenectomy (RRH) in patients with early cervical cancer (ECC).MATERIAL AND METHOD... | ['Adenocarcinoma', 'Adenocarcinoma, Clear Cell', 'Adult', 'Aged', 'Aged, 80 and over', 'Blood Loss, Surgical', 'Carcinoma, Adenosquamous', 'Carcinoma, Squamous Cell', 'Conversion to Open Surgery', 'Female', 'Humans', 'Hysterectomy', 'Laparoscopy', 'Length of Stay', 'Lymph Node Excision', 'Lymph Nodes', 'Middle Aged', '... | 25,468,748 | [['C04.557.470.200.025'], ['C04.557.470.200.025.045'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.414.300', 'C23.550.505.300'], ['C04.557.435.250', 'C04.557.470.200.150'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E04.502.250.155'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Selective apoptosis of breast cancer cells by siRNA targeting of BORIS. | Brother of the regulator of imprinted sites (BORIS) is an epigenetically acting transcription factor which represses the tumor inhibitor functions of the tumor suppressor protein CTCF. BORIS expression has not been documented in adult females, making it an exciting molecular target for drug development in breast cancer... | ['Apoptosis', 'Base Sequence', 'Breast Neoplasms', 'Caspase 3', 'Caspase 7', 'Cell Line, Tumor', 'Cell Survival', 'DNA-Binding Proteins', 'Female', 'Humans', 'Molecular Sequence Data', 'RNA, Small Interfering', 'Transfection'] | 18,355,444 | [['G04.146.954.035'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.588.180', 'C17.800.090.500'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D08.811.277.656.262.500.126.350.700', 'D08.811.277.656.300.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Histochemical and histopathological liver aspects during pneumocystosis. | 124 liver fragments taken on autopsy from children presenting pneumocystosis in the final stage were histochemically and histopathologically studied. There were predominantly metabolic disturbances (albuminous degeneration and fatty changes of hepatocytes) and reduced inflammatory cell infiltrates. Histochemically ther... | ['Adipose Tissue', 'Child, Preschool', 'Cholestasis', 'Humans', 'Infant', 'Infant, Newborn', 'Liver', 'Necrosis', 'Pneumonia, Pneumocystis', 'Reticulin'] | 6,457,985 | [['A10.165.114'], ['M01.060.406.448'], ['C06.130.120.135'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['A03.620'], ['C23.550.717'], ['C01.150.703.534.700', 'C01.150.703.770.700', 'C01.748.435.700', 'C01.748.610.675', 'C08.381.472.700', 'C08.381.677.675', 'C08.730.435.700', '... | ['Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The large data base file structure dilemma. | This paper first presents a brief tutorial on the principal random file organization methods for handling two major applications--Transaction oriented systems and information storage and retrieval systems. It then addresses a particular large data base dilemma, not satisfactorily resolved by any of these methods, and w... | ['Computers', 'Electronic Data Processing', 'Information Systems', 'Statistics as Topic'] | 1,127,028 | [['L01.224.230.260'], ['L01.224.085'], ['L01.313.500.750.300'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Locomotor activity and discriminative stimulus effects of a novel series of synthetic cathinone analogs in mice and rats. | RATIONALE: Recent years have seen an increase in the recreational use of novel, synthetic psychoactive substances. There are little or no data on the abuse liability of many of the newer compounds.OBJECTIVES: The current study investigated the discriminative stimulus and locomotor effects of a series of synthetic analo... | ['Alkaloids', 'Amphetamines', 'Animals', 'Discrimination Learning', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Illicit Drugs', 'Locomotion', 'Male', 'Methamphetamine', 'Mice', 'Propiophenones', 'Psychotropic Drugs', 'Pyrrolidines', 'Rats', 'Rats, Sprague-Dawley', 'Thiophenes'] | 28,210,779 | [['D03.132'], ['D02.092.471.683.152'], ['B01.050'], ['F02.463.425.280'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G07.690.936.500'], ['D26.878'], ['G07.568.500', 'G11.427.410.568'], ['D02.092.471.683.152.619'], ['B01.050.150.900.649.313.992.635.505.500'], ['D02.522.818'], ['D27.505.954.427.70... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Complementation analysis of the murine scid cell line. | It has been shown that several X-ray-sensitive Chinese hamster cell mutants defective in repair of DNA double-strand breaks (DSBs) are also impaired in the process of V(D)J recombination. The hamster mutants with this phenotype represent three distinct complementation groups, represented by the xrs series, XR-1 and V-3... | ['Animals', 'Cell Line', 'Chromosomes, Human, Pair 8', 'Cricetinae', 'DNA Damage', 'DNA Repair', 'Genetic Complementation Test', 'Humans', 'Mice', 'Mice, SCID', 'Mutation'] | 7,652,160 | [['B01.050'], ['A11.251.210'], ['A11.284.187.520.300.325.340', 'G05.360.162.520.300.325.340'], ['B01.050.150.900.649.313.992.635.075.250'], ['G05.200'], ['G02.111.222', 'G05.219'], ['E05.393.281.526'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.31... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Expression of HMGB1 protein in breast cancer and its clinicopathological significance]. | Objective: To investigate the expression and clinicopathological significance of high mobility group box protein B1 (HMGB1) protein in breast cancer. Methods: The expression of HMGB1 protein in 26 normal breast tissues and 417 invasive breast cancer tissues diagnosed at Dongyang People's Hospital, Zhejiang Province fro... | ['Biomarkers, Tumor', 'Breast Neoplasms', 'HMGB1 Protein', 'Humans', 'Prognosis', 'Receptors, Estrogen'] | 31,914,536 | [['D23.101.140'], ['C04.588.180', 'C17.800.090.500'], ['D12.776.260.356.300', 'D12.776.660.235.400.600.300', 'D12.776.664.235.400.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789'], ['D12.776.826.750.350', 'D12.776.930.778.350']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distribution of DNA damage in the sperm nucleus: A study of zebrafish as a model of histone-packaged chromatin. | Reproductive defects can occur when the integrity of the male gamete genome is affected. Sperm chromatin is not homogeneous, having relaxed regions which are more accessible to the transcription machinery in the embryo, and thought to be specially sensitive to DNA damage. The level of damage in specific genes located i... | ['Animals', 'Cell Nucleus', 'Chromatin', 'DNA Damage', 'DNA Fragmentation', 'Histones', 'Hydrogen Peroxide', 'In Situ Nick-End Labeling', 'Male', 'Models, Genetic', 'Spermatozoa', 'Zebrafish'] | 30,245,333 | [['B01.050'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['G05.200'], ['G05.200.230'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', ... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prehypertension: a literature-documented public health concern. | PURPOSE: To provide nurse practitioners (NPs) with an overview of prehypertension identification and management. Additionally, the article serves to highlight the prevalence and impact of prehypertension in the United States.DATA SOURCES: A comprehensive review of the literature was conducted using multiple databases, ... | ['Health Promotion', 'Humans', 'Nurse Practitioners', 'Prehypertension', 'Public Health', 'United States'] | 22,243,675 | [['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.650.640', 'N02.360.650.640'], ['C14.907.653'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Protein Immobilization onto Cationic Spherical Polyelectrolyte Brushes Studied by Small Angle X-ray Scattering. | The immobilization of bovine serum albumins (BSA) onto cationic spherical polyelectrolyte brushes (SPB) consisting of a solid polystyrene (PS) core and a densely grafted poly(2-aminoethyl methacrylate hydrochloride) (PAEMH) shell was studied by small-angle X-ray scattering (SAXS). The observed dynamics of adsorption of... | ['Cations', 'Immobilized Proteins', 'Methacrylates', 'Polyelectrolytes', 'Scattering, Small Angle', 'Serum Albumin, Bovine', 'X-Rays'] | 28,398,743 | [['D01.248.497.300'], ['D12.776.463'], ['D02.241.081.069.600'], ['D01.248.700', 'D05.750.230'], ['E05.196.822.830', 'G01.867.755'], ['D12.776.034.841.540', 'D12.776.124.727.875'], ['G01.358.500.505.970', 'G01.750.250.970', 'G01.750.750.918']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Insulin immunohistochemistry of rodent CNS: apparent species differences but good correlation with radioimmunological data. | Using an indirect immunofluorescence technique the distribution of insulin was mapped in brains of Wistar strain rats and mice. Insulin immunoreactivity was found to be widely distributed throughout mouse CNS, whereas in rat brain a restriction of immunoreactive material to cerebral blood vessels and ependymal cells an... | ['Animals', 'Brain Chemistry', 'Diabetes Mellitus, Experimental', 'Fluorescent Antibody Technique', 'Histocytochemistry', 'Insulin', 'Mice', 'Mice, Inbred C57BL', 'Radioimmunoassay', 'Rats', 'Species Specificity'] | 7,021,484 | [['B01.050'], ['G02.111.150', 'G03.185'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Toward a mechanistic explanation of phenotypic evolution: The need for a theory of theory integration. | Reconciling different underlying ontologies and explanatory contexts has been one of the main challenges and impediments for theory integration in biology. Here, we analyze the challenge of developing an inclusive and integrative theory of phenotypic evolution as an example for the broader challenge of developing a the... | ['Animals', 'Biological Evolution', 'Informatics', 'Logic', 'Models, Biological'] | 29,356,321 | [['B01.050'], ['G05.045', 'G16.075'], ['L01.313'], ['K01.752.448'], ['E05.599.395']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The pharmacokinetic-pharmacodynamic model of azithromycin for lipopolysaccharide-induced depressive-like behavior in mice. | A mechanism-based model was developed to describe the time course of lipopolysaccharide-induced depressive-like behavior and azithromycin pharmacodynamics in mice. The lipopolysaccharide-induced disease progression was monitored by lipopolysaccharide, proinflammatory cytokines, and kynrenine concentration in plasma. Th... | ['Animals', 'Anti-Bacterial Agents', 'Azithromycin', 'Behavior, Animal', 'Depression', 'Lipopolysaccharides', 'Mice', 'Stress, Physiological'] | 23,358,536 | [['B01.050'], ['D27.505.954.122.085'], ['D02.540.576.500.992.050'], ['F01.145.113'], ['F01.145.126.350'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['G07.775']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Possibility and clinical significance of reservation middle turbinate in endoscopic sinus surgery]. | OBJECTIVE: To study the possibility and significance or reservation of the middle turbinate in endoscopic sinus surgery for sinusitis and/or nasal polyps.METHODS: (1) The morphology and mucosal ultrastructure of middle turbinate were observed preoperatively and postoperatively by nasal endoscopy and scanning electron m... | ['Adolescent', 'Adult', 'Child', 'Endoscopy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nasal Polyps', 'Sinusitis', 'Turbinates'] | 12,764,792 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C08.460.572', 'C09.603.557', 'C23.300.825.557'], ['C01.748.749', 'C08.460.692.752', 'C08.730.749', 'C09.603.692.752'], ['A02.835.232.781.324.948', 'A04.531.898'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Alleviation of asthma-related symptoms by a derivative of L-allo threonine. | Chronic asthma is characterized by inflammatory cell infiltration and tissue remodeling, leading to subepithelial inflammation. In order to evaluate the anti-asthmatic activity of LX519290, a derivative of L-allo threonine, we performed several in vitro and in vivo anti-asthmatic assays. Using ovalbumin (OVA)-sensitize... | ['Animals', 'Anti-Asthmatic Agents', 'Asthma', 'Cell Line', 'Cell Survival', 'Cytokines', 'Humans', 'Hydrazines', 'Immunohistochemistry', 'Lung', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Ovalbumin', 'Pneumonia', 'Polymerase Chain Reaction', 'Signal Transduction', 'Threonine'] | 23,381,610 | [['B01.050'], ['D27.505.954.796.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['A11.251.210'], ['G04.346'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.442'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Prolongation of life span in hypertensive rats by dietary interventions. Effects of garlic and linseed oil. | The effects of long-term dietary application of garlic (dried powder, 0.5% in weight of standard chow; G group) or linseed oil (2.5%; L group) as well as a combination of both interventions (L + G group) on the life span of hypertensive rats (SHR SP) was investigated. A further group fed with standard chow served as co... | ['Animals', 'Blood Pressure', 'Cathartics', 'Disease Models, Animal', 'Garlic', 'Heart Rate', 'Hypertension', 'Hypertrophy, Left Ventricular', 'Linseed Oil', 'Longevity', 'Male', 'Plants, Medicinal', 'Random Allocation', 'Rats', 'Rats, Inbred SHR'] | 9,342,429 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D27.505.954.483.396'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.650.940.800.575.912.250.618.100.050.060.300'], ['E01.370.600.875.500', 'G09.330.380.500'], ['C14.907.489'], ['C14.280.195.400', 'C23.300.775.250.400'], ['D10.212.507.550', 'D10.627.700... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Neurotensin-SPDP-poly-L-lysine conjugate: a nonviral vector for targeted gene delivery to neural cells. | We report herein the synthesis of a novel DNA delivery system and in vitro evidence of its ability to transfect cell lines by binding to the high-affinity neurotensin receptor and subsequent internalization of ligand-receptor complexes. The targeting vehicle consisted of neurotensin crosslinked with poly-L-lysine via N... | ['Animals', 'Chloramphenicol O-Acetyltransferase', 'Cross-Linking Reagents', 'DNA-Binding Proteins', 'Endocytosis', 'Gene Targeting', 'Genetic Code', 'Genetic Vectors', 'Neuroblastoma', 'Neurons', 'Neurotensin', 'Polylysine', 'Rats', 'Succinimides', 'Tumor Cells, Cultured'] | 10,366,746 | [['B01.050'], ['D08.811.913.050.134.170'], ['D27.720.470.410.210'], ['D12.776.260'], ['G04.417'], ['E05.393.335'], ['G05.360.335'], ['G05.360.337'], ['C04.557.465.625.600.590.650.550', 'C04.557.470.670.590.650.550', 'C04.557.580.625.600.590.650.550'], ['A08.675', 'A11.671'], ['D12.644.400.550', 'D12.776.631.650.550'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Trillium-coated oxygenators in adult open-heart surgery: a prospective randomized trial. | This randomized, prospective clinical trial examines the impact of the use of Trillium biopassive surface coating on clinical outcomes after cardiopulmonary bypass (CPB) that may be induced by contact of blood elements with foreign surfaces. The study consisted of 98 consecutive patients randomly assigned to either a C... | ['Aged', 'Cardiopulmonary Bypass', 'Coated Materials, Biocompatible', 'Female', 'Humans', 'Male', 'Middle Aged', 'Oxygenators', 'Postoperative Care', 'Prospective Studies', 'Treatment Outcome', 'Trillium', 'United States'] | 12,533,060 | [['M01.060.116.100'], ['E04.292.413'], ['D25.130.420', 'J01.637.051.130.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.652'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.722.700'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E01.78... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
q-space and conventional diffusion imaging of axon and myelin damage in the rat spinal cord after axotomy. | Parallel and perpendicular diffusion properties of water in the rat spinal cord were investigated 3 and 30 days after dorsal root axotomy, a specific insult resulting in early axonal degeneration followed by later myelin damage in the dorsal column white matter. Results from q-space analysis (i.e., the diffusion probab... | ['Animals', 'Axons', 'Axotomy', 'Diffusion Magnetic Resonance Imaging', 'Female', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Myelin Sheath', 'Rats', 'Rats, Inbred Lew', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Spinal Cord Injuries'] | 20,432,303 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['E04.525.210.158'], ['E01.370.350.825.500.150'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['A08.637.600.500', 'A08.637.800.500', 'A08.675.542.512.560', 'A08.800.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Low vector competence in sylvatic mosquitoes limits Zika virus to initiate an enzootic cycle in South America. | Zika virus (ZIKV) has spread in the Americas since 2015 and the potential establishment of a sylvatic transmission cycle in the continent has been hypothesized. We evaluated vector competence of five sylvatic Neotropical mosquito species to two ZIKV isolates. Distinct batches of Haemagogus leucoceleanus, Sabethes albip... | ['Animals', 'Disease Vectors', 'Humans', 'Mosquito Vectors', 'Public Health Surveillance', 'South America', 'Viral Load', 'Zika Virus', 'Zika Virus Infection'] | 31,882,976 | [['B01.050'], ['N06.850.335.188', 'N06.850.520.203.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.188.100.500.500', 'N06.850.520.203.375.100.500.500'], ['E05.318.308.980.438.700.324', 'N05.715.360.300.800.438.625.324', 'N06.850.520.308.980.438.700.324', 'N06.850.780.675.487'], ['Z01.107.757'], ['... | ['Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Damage to the corneal endothelium during Nd/YAG photodisruption. | Damage to the human corneal endothelium, as seen by specular microscopy, associated with short pulsed neodymium: yttrium-aluminium-garnet (Nd/YAG) laser iridotomy and capsulotomy, is described. A specular and scanning electron microscopical study of fresh in vitro rabbit eyes submitted to Nd/YAG iridotomy was performed... | ['Animals', 'Cataract Extraction', 'Child', 'Cornea', 'Corneal Injuries', 'Endothelium', 'Glaucoma', 'Humans', 'In Vitro Techniques', 'Iris', 'Lasers', 'Male', 'Microscopy, Electron, Scanning', 'Rabbits'] | 3,838,136 | [['B01.050'], ['E04.540.825.249'], ['M01.060.406'], ['A09.371.060.217'], ['C10.900.300.284.250.124', 'C11.204.284', 'C11.297.374', 'C26.915.300.425.250.124'], ['A10.272.491'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A09.371.060.450', 'A09.371.894.513'], ['E07.632.490', 'E07.710.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Nebivolol prevents vascular oxidative stress and hypertension in rats chronically treated with ethanol. | BACKGROUND AND AIMS: Chronic ethanol consumption is associated with hypertension and atherosclerosis. Vascular oxidative stress is described as an important mechanism whereby ethanol predisposes to atherosclerosis. We hypothesized that nebivolol would prevent ethanol-induced hypertension and vascular oxidative stress.M... | ['Adrenergic beta-1 Receptor Antagonists', 'Animals', 'Antihypertensive Agents', 'Aorta, Thoracic', 'Arterial Pressure', 'Biomarkers', 'Catalase', 'Disease Models, Animal', 'Epinephrine', 'Ethanol', 'Hypertension', 'Lipid Peroxidation', 'Male', 'NADPH Oxidases', 'Nebivolol', 'Nitric Oxide', 'Norepinephrine', 'Oxidative... | 29,753,230 | [['D27.505.519.625.050.200.200.100', 'D27.505.696.577.050.200.200.100'], ['B01.050'], ['D27.505.954.411.162'], ['A07.015.114.056.372'], ['G09.330.380.076.347'], ['D23.101'], ['D08.811.682.732.332'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dietary modulation of estrous cyclicity in singly and multiply housed C57BL/6J mice. | Two commercial diets differed markedly in their ability to support estrous cyclicity in both singly and multiply housed, 3- to 4-month-old virgin C57BL/6J mice. When fed a breeder diet developed to promote reproduction, mice had shorter cycles and a decreased number of acyclic intervals than when fed a standard diet. I... | ['Animal Feed', 'Animals', 'Estrus', 'Female', 'Mice', 'Mice, Inbred Strains', 'Pregnancy', 'Reproduction', 'Social Environment'] | 6,539,404 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['G08.686.195.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ['G08.686.784.769'], ['G08.686.784'], ['I01.880.853.500']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
Tracking nickel-adaptive biomarkers in Pisolithus albus from New Caledonia using a transcriptomic approach. | The fungus Pisolithus albus forms ectomycorrhizal (ECM) associations with plants growing on extreme ultramafic soils, which are naturally rich in heavy metals such as nickel. Both nickel-tolerant and nickel-sensitive isolates of P. albus are found in ultramafic soils in New Caledonia, a biodiversity hotspot in the Sout... | ['Adaptation, Physiological', 'Basidiomycota', 'Biodiversity', 'Biomarkers', 'Ecosystem', 'Gene Expression Regulation, Fungal', 'Genetic Variation', 'Molecular Sequence Annotation', 'Mycorrhizae', 'New Caledonia', 'Nickel', 'Phylogeny', 'Plants', 'Sequence Analysis, DNA', 'Soil Microbiology', 'Transcriptome'] | 22,429,322 | [['G07.025', 'G16.012.500'], ['B01.300.179'], ['G16.500.275.157.049', 'N06.230.124.049'], ['D23.101'], ['G16.500.275.157', 'N06.230.124'], ['G05.308.330'], ['G05.365'], ['E05.393.760.479', 'L01.453.245.667.580'], ['A18.400.525', 'A19.690', 'B01.300.655', 'B05.550'], ['Z01.639.760.590.620'], ['D01.268.556.607', 'D01.268... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Insulin binding to microvascular endothelium of intact heart: a kinetic and morphometric analysis. | We have studied insulin binding to blood vessels of the intact, beating heart. The beating hearts were perfused with [125I]iodoinsulin (3 X 10(-10) M) followed by perfusion with unlabeled insulin. The unlabeled insulin displaced the bound [125I]iodoinsulin in direct proportion to the concentration of the unlabeled horm... | ['Animals', 'Autoradiography', 'Capillaries', 'Coronary Vessels', 'Heart', 'Insulin', 'Iodine Radioisotopes', 'Kinetics', 'Male', 'Microscopy, Electron', 'Perfusion', 'Rats', 'Receptor, Insulin'] | 6,342,413 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['A07.015.461.165'], ['A07.015.114.269', 'A07.015.908.194'], ['A07.541'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['G01.374.661', 'G02.111.490'], ['E01.370.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The painful shoulder: MR imaging of the glenohumeral joint. | We used magnetic resonance imaging in 41 patients with shoulder pain. Magnetic resonance was found useful in depicting the spectrum of rotator cuff abnormalities associated with mechanical impingement including both large and small rotator cuff tears as well as tendinitis. Abnormalities of the capsular mechanism, osseo... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bursitis', 'Humans', 'Image Enhancement', 'Magnetic Resonance Imaging', 'Middle Aged', 'Pain', 'Reference Values', 'Shoulder Joint', 'Tendinopathy'] | 3,183,135 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C05.550.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E05.978.810'], ['A02.8... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Measuring the nursing workload in intensive care with the Nursing Activities Score (NAS): A prospective study in 16 hospitals in Belgium. | PURPOSE: The evaluation of nursing workload is a common practice in intensive care units (ICUs). It allows the calculation of an optimal nurse/patient ratio (N/P) which is a major challenge to ensuring the quality of care while controlling the costs of health care. The objectives of this study were, therefore, to evalu... | ['Algorithms', 'Belgium', 'Critical Care Nursing', 'Female', 'Humans', 'Intensive Care Units', 'Male', 'Middle Aged', 'Nursing Staff, Hospital', "Practice Patterns, Nurses'", 'Prospective Studies', 'Workload'] | 31,521,017 | [['G17.035', 'L01.224.050'], ['Z01.542.115'], ['H02.478.676.175', 'N02.421.533.149'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['M01.060.116.630'], ['M01.526.485.680.490', 'M01.526.485.740.523', 'N02.360.680.490', 'N02.360.740.523'], ['N04.590.374.553', 'N05.300.581'], ['E05.318.372.500.750... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Immunogenic proteins specific to different bird species in bird fancier's lung. | Bird fancier's lung (BFL) is a disease produced by exposure to avian proteins present in droppings, blooms, and serum of a variety of birds. Although serological test results are currently used to confirm clinical diagnosis of the disease, bird species specificity is poorly understood. This study aimed to contribute to... | ['Animals', 'Antigens', "Bird Fancier's Lung", 'Chickens', 'Columbidae', 'Electrophoresis, Polyacrylamide Gel', 'Humans', 'Melopsittacus', 'Species Specificity'] | 24,786,679 | [['B01.050'], ['D23.050'], ['C08.381.483.125.125', 'C08.674.055.125', 'C20.543.480.680.075.125', 'C24.125'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['B01.050.150.900.248.165.150'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.248.710... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid emergence of resistance in Pseudomonas aeruginosa in cystic fibrosis patients due to in-vivo selection of stable partially derepressed beta-lactamase producing strains. | The development of significant mechanisms of resistance to beta-lactam antibiotics in Pseudomonas aeruginosa in cystic fibrosis (CF) patients have been studied in ten CF patients during a two week course of anti-pseudomonal beta-lactam antibiotic therapy. Sputum samples were collected on days 1, 7 and 15. Entire homoge... | ['Adolescent', 'Adult', 'Anti-Bacterial Agents', 'Child', 'Cystic Fibrosis', 'Drug Resistance, Microbial', 'Female', 'Humans', 'Male', 'Penicillanic Acid', 'Pseudomonas aeruginosa', 'Sputum', 'Tazobactam', 'beta-Lactamase Inhibitors', 'beta-Lactamases'] | 2,170,321 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.085'], ['M01.060.406'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['G06.225', 'G07.690.773.984.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.589.099.750.687', 'D02.886.108.750.687', 'D03.633.100.300.750.687'], ['B03.440.400.425... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Columella pressure necrosis: a method of surgical reconstruction and its long-term outcome. | Nasal continuous positive airway pressure (nCPAP) in premature babies may rarely lead to necrosis of the columella. Subsequent functional and cosmetic impairments require surgical corrections to restore nasal anatomy and architecture. The objective of this report is to document the technique of reconstruction in a baby... | ['Continuous Positive Airway Pressure', 'Follow-Up Studies', 'Humans', 'Infant', 'Male', 'Nose Diseases', 'Pressure Ulcer', 'Rhinoplasty', 'Time Factors'] | 25,096,650 | [['E02.041.625.790.259', 'E02.880.820.790.259'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C08.460', 'C09.603'], ['C17.800.893.665'], ['E02.218.755', 'E04.580.392.500', 'E04.680.650'], ['G01.910.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of the accreditation council for graduate medical education duty hour limits on sleep, work hours, and safety. | OBJECTIVE: To mitigate the risks of fatigue-related medical errors, the Accreditation Council for Graduate Medical Education introduced work hour limits for resident physicians in 2003. Our goal was to determine whether work hours, sleep, and safety changed after implementation of the Accreditation Council for Graduate... | ['Accreditation', 'Adult', 'Cohort Studies', 'Education, Medical, Graduate', 'Female', 'Guideline Adherence', 'Guidelines as Topic', 'Humans', 'Internship and Residency', 'Male', 'Medical Errors', 'Personnel Staffing and Scheduling', 'Probability', 'Prospective Studies', 'Safety', 'Sleep Deprivation', 'United States', ... | 18,676,540 | [['N03.706.110.070', 'N05.700.200.100'], ['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['I02.358.337.350', 'I02.358.399.350'], ['N04.761.337', 'N05.715.360.395'], ['N04.761.700.350', 'N05.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500'... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Hospitalization by cytotoxic chemotherapy regimen among older women with stage IV breast cancer. | BACKGROUND: Older patients with cancer are at risk for increased side effects of treatment. Our goal was to inform treatment for older patients by analyzing the relationship between chemotherapy regimen and hospitalization among older women receiving palliative cytotoxic chemotherapy for breast cancer.METHOD: We identi... | ['Aged', 'Aged, 80 and over', 'Antineoplastic Agents', 'Breast Neoplasms', 'Capecitabine', 'Cyclophosphamide', 'Deoxycytidine', 'Docetaxel', 'Doxorubicin', 'Female', 'Hospitalization', 'Humans', 'Linear Models', 'Neoplasm Staging', 'Retrospective Studies', 'SEER Program', 'Survival Analysis'] | 30,264,853 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['D03.383.742.680.245.500.425', 'D03.383.742.698.875.404.425', 'D13.570.230.329.313', 'D13.570.685.245.500.425'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D03.383.742.680.245.500', 'D13.570.230.329',... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evidence of Objective Memory Impairments in Deployed Gulf War Veterans With Subjective Memory Complaints. | INTRODUCTION: Despite the fact that many veterans returned from the 1991 Gulf War (GW) with complaints of memory difficulties, most neuropsychological studies to date have found little evidence of a correspondence between subjective and objective measures of cognitive function in GW veterans. However, if GW veterans co... | ['Adult', 'Anxiety', 'California', 'Chemical Warfare Agents', 'Fatigue', 'Female', 'Gulf War', 'Humans', 'Male', 'Memory Disorders', 'Middle Aged', 'Musculoskeletal Pain', 'Neuropsychological Tests', 'Organophosphorus Compounds', 'Persian Gulf Syndrome', 'Sarin', 'Stress Disorders, Post-Traumatic', 'Veterans'] | 29,087,904 | [['M01.060.116'], ['F01.470.132'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['D27.720.777.300', 'D27.888.569.612.150', 'J01.637.870.900.200'], ['C23.888.369'], ['I01.880.735.950.250.657', 'K01.400.504.968.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.525', 'C23.888.592.604.529', '... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 |
Self-report and objective measures of ADHD-related behaviors in parents of preschool children at risk for ADHD. | OBJECTIVE: Few studies have used a combination of objective and self-report measures to examine neuropsychological and behavioral functioning in parents of children with attention-deficit/hyperactivity disorder (ADHD). This study examined attention and inhibitory control in the parents of preschool children who were ra... | ['Adult', 'Attention Deficit Disorder with Hyperactivity', 'Child', 'Child of Impaired Parents', 'Cognition Disorders', 'Humans', 'Neuropsychological Tests', 'Parents', 'Risk Factors', 'Self-Assessment'] | 15,337,861 | [['M01.060.116'], ['F03.625.094.150'], ['M01.060.406'], ['M01.106'], ['F03.615.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Fingolimod-induced leukoencephalopathy in a patient with neuromyelitis optica spectrum disorder. | Fingolimod (FTY720) is used for reducing the annualized relapse rate and slowing progression of neurological disability in relapsing-remitting forms of multiple sclerosis (MS). However, its safety is not confirmed in patients with neuromyelitis optica spectrum disorder (NMOSD), who characteristically have positive aqua... | ['Aquaporin 4', 'Brain', 'Female', 'Fingolimod Hydrochloride', 'Humans', 'Immunosuppressive Agents', 'Leukoencephalopathies', 'Magnetic Resonance Imaging', 'Middle Aged', 'Neuromyelitis Optica', 'Spinal Cord'] | 27,237,757 | [['D12.776.157.530.400.500.040.468', 'D12.776.543.550.450.730.040.468', 'D12.776.543.585.400.730.040.577'], ['A08.186.211'], ['D02.033.100.700.350', 'D02.033.455.706.431', 'D02.092.063.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['C10.228.140.695'], ['E01.370.350.825.500'], ['M0... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Systematic review and network meta-analysis of first-line therapy for advanced EGFR | Here, we compare the relative clinical efficacy of EGFR-targeted tyrosine kinase inhibitors (EGFR TKIs) for EGFR-positive advanced non-small-cell lung cancer (NSCLC). The authors systematically searched 11 electronic databases from January 2004 to August 2018 for randomized controlled trials measuring clinical efficacy... | ['Bayes Theorem', 'Carcinoma, Non-Small-Cell Lung', 'Disease-Free Survival', 'ErbB Receptors', 'Humans', 'Lung Neoplasms', 'Network Meta-Analysis', 'Protein Kinase Inhibitors'] | 31,298,572 | [['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Gastroesophageal reflux disease and mucosal injury with emphasis on short-segment Barrett's esophagus and duodenogastroesophageal reflux. | Gastroeosphageal reflux disease has been associated with long segments of Barrett's esophagus </=3 cm), but little is known about its association with shorter segments. The aim of this study was to evaluate anatomic and physiologic alterations of the cardia and esophageal exposure to gastric and duodenal juice in patie... | ['Adult', 'Aged', 'Aged, 80 and over', 'Barrett Esophagus', 'Bilirubin', 'Cardia', 'Chi-Square Distribution', 'Esophagitis', 'Esophagogastric Junction', 'Esophagoscopy', 'Female', 'Gastroesophageal Reflux', 'Humans', 'Hydrogen-Ion Concentration', 'Intestines', 'Male', 'Manometry', 'Metaplasia', 'Middle Aged', 'Statisti... | 10,457,313 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.834.154', 'C06.405.117.102'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['A03.556.875.875.163'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'],... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Increased hydrogen peroxide in the exhaled breath of uraemic patients unaffected by haemodialysis. | BACKGROUND: Uraemia is accompanied by conditions favouring the rise of H2O2 activity in body fluids. This results from the increased release of H2O2 by polymorphonuclear leukocytes and decreased plasma glutathione peroxidase activity. The purpose of this study was to determine if patients on chronic haemodialysis (HD) ... | ['Adult', 'Breath Tests', 'Female', 'Humans', 'Hydrogen Peroxide', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Renal Dialysis', 'Uremia'] | 14,671,051 | [['M01.060.116'], ['E01.370.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630'], ['E02.870.300', 'E02.912.800'], ['C12.777.419.936', 'C13.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Assessing impairment and disability of facial paralysis in patients with vestibular schwannoma. | OBJECTIVE: To evaluate facial impairment and disability with respect to quality of life in patients with facial paresis after vestibular schwannoma surgery.DESIGN: Cross-sectional observational study.SETTING: Academic, tertiary care hospital.PATIENTS: All consecutive patients during a 5-year period who underwent vestib... | ['Cross-Sectional Studies', 'Face', 'Facial Paralysis', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neuroma, Acoustic', 'Postoperative Complications', 'Quality of Life', 'Surveys and Questionnaires'] | 17,224,525 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['A01.456.505'], ['C07.465.327', 'C10.597.622.214', 'C23.888.592.636.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.465.625.650.595.610', 'C04.557.580.600.610.595.610', 'C04.557.580.625.650.595.610', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Temporal and spatial biomonitoring of heavy metals in eastern Aegean coastal waters using Amphibalanus amphitrite. | This biomonitoring study presents the spatial and temporal distributions of heavy metals in the soft tissues of a major fouling species Amphibalanus amphitrite living on hard substrate at different sites along the eastern Aegean coast. A. amphitrite has been chosen as a strong candidate for monitoring heavy metals. Sed... | ['Analysis of Variance', 'Animals', 'Data Collection', 'Environmental Monitoring', 'Environmental Pollutants', 'Geologic Sediments', 'Mediterranean Sea', 'Metals, Heavy', 'Seawater', 'Spectrophotometry, Atomic', 'Thoracica', 'Turkey'] | 21,920,561 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D27.888.284'], ['G01.311.330', 'G16.500.320'], ['Z01.756.592'], ['D01.268.556', 'D01.552.544'], ['G16.500.275.725.500'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Modulation of the CD40-CD40 ligand interaction using human anti-CD40 single-chain antibody fragments obtained from the n-CoDeR phage display library. | CD40 plays a central regulatory role in the immune system and antibodies able to modulate CD40 signalling may consequently have a potential in immunotherapy, in particular for treatment of lymphomas and autoimmune disease like multiple sclerosis. As a first step to achieve this goal, we describe the selection and chara... | ['Antibody Specificity', 'Apoptosis', 'B-Lymphocytes', 'Binding, Competitive', 'CD40 Antigens', 'CD40 Ligand', 'Cell Division', 'Epitope Mapping', 'Humans', 'Immunoglobulin Fragments', 'Lymphocyte Activation', 'Peptide Library', 'Polymerase Chain Reaction'] | 12,153,507 | [['G12.100'], ['G04.146.954.035'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D12.776.465.750', 'D12.776.543.750.705.852.760.097', 'D23.050.301.264.051.140', 'D23.101.100.150.140'], ['D... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Minimally invasive perventricular device closure of ventricular septal defect in infants under transthoracic echocardiograhic guidance: feasibility and comparison with transesophageal echocardiography. | BACKGROUND: A hybrid approach to minimally invasive perventricular closure of VSD in infants is safe and effective, and has been performed under guidance of transesophageal echocardiography (TEE). We applied transthoracic echocardiographic (TTE) guidance to this hybrid approach, and compare results guided by TTE with t... | ['Echocardiography', 'Echocardiography, Transesophageal', 'Female', 'Follow-Up Studies', 'Heart Septal Defects, Ventricular', 'Heart Ventricles', 'Humans', 'Infant', 'Male', 'Minimally Invasive Surgical Procedures', 'Monitoring, Intraoperative', 'Prosthesis Design', 'Retrospective Studies', 'Septal Occluder Device', 'T... | 23,497,100 | [['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C14.240.400.560.540', 'C14.280.400.560.540', 'C16.131.240.400.560.540'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Lower concentrations of thrombin-antithrombin complex (TAT) correlate to higher recanalisation rates among ischaemic stroke patients treated with t-PA. | An elevated concentration of the thrombin-antithrombin complex (TAT) has been associated with high mortality rates and poor outcome in ischaemic stroke patients treated with tissue plasminogen activator (t-PA). Moreover, antithrombin drugs have been tested in combination with t-PA in the acute phase of ischaemic stroke... | ['Aged', 'Aged, 80 and over', 'Antithrombin III', 'Biomarkers', 'Brain Ischemia', 'Female', 'Fibrinolytic Agents', 'Humans', 'Infarction, Middle Cerebral Artery', 'Male', 'Middle Aged', 'Peptide Hydrolases', 'Prognosis', 'Protein Binding', 'Risk Factors', 'Stroke', 'Thrombin', 'Tissue Plasminogen Activator', 'Treatment... | 19,806,263 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.644.861.060.500', 'D12.776.124.790.106.125', 'D12.776.377.715.085.125', 'D12.776.872.060.500', 'D23.113.025'], ['D23.101'], ['C10.228.140.300.150', 'C14.907.253.092'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Immunogenetic analysis of successful and rejected bone marrow grafts within one family. | We report the case of an Indonesian patient who required urgent bone marrow transplantation for acute leukaemia and who received successive transplants from two siblings. The first transplant failed while the second was successful. There were some uncertainties in serological typing due to the presence of cross-reactin... | ['Adult', 'Australia', 'Bone Marrow Transplantation', 'Female', 'Graft Rejection', 'Graft Survival', 'Haplotypes', 'Histocompatibility Testing', 'Humans', 'Indonesia', 'Leukemia, Megakaryoblastic, Acute', 'Major Histocompatibility Complex', 'Male', 'Myelodysplastic Syndromes', 'Nuclear Family', 'Polymerase Chain Reacti... | 9,098,445 | [['M01.060.116'], ['Z01.639.100', 'Z01.678.100.373'], ['E02.095.147.725.040', 'E04.936.580.040'], ['G12.875.545.328'], ['G12.875.545.340'], ['G05.380.360'], ['E01.370.225.812.385', 'E05.200.812.385', 'E05.478.594.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.145.380', 'Z01.639.580'], ['C04.557.337.5... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Electrocatalytic degradation of perfluoroocatane sulfonate (PFOS) on a 3D graphene-lead dioxide (3DG-PbO2 | In this work, a three-dimension grapnene-PbO2 (3DG-PbO2) composite anode was prepared using coelectrodeposition technology for electrocatalytic oxidation of perfluorooctane sulfonate (PFOS). The effect of 3DG on the surface morphology, structure and electrocatalytic activity of PbO2 electrode was investigated. The resu... | ['Alkanesulfonic Acids', 'Animals', 'Electrochemical Techniques', 'Electrodes', 'Electroplating', 'Embryo, Nonmammalian', 'Fluorocarbons', 'Graphite', 'Lead', 'Nanocomposites', 'Oxidation-Reduction', 'Oxides', 'Titanium', 'Water Pollutants, Chemical', 'Zebrafish'] | 32,663,673 | [['D02.455.326.146.100', 'D02.886.645.600.055'], ['B01.050'], ['E05.301'], ['E07.305.250'], ['E05.301.250.348'], ['A13.350', 'A16.331'], ['D02.455.526.510.435'], ['D01.268.150.300', 'D01.578.300'], ['D01.268.556.435', 'D01.552.544.435'], ['J01.637.512.150'], ['G02.700', 'G03.295.531'], ['D01.248.497.158.685', 'D01.650.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Drug absorption from inhalation aerosols administered by positive-pressure ventilation. I: Administration of a characterized, solid disodium fluorescein aerosol under a controlled respiratory regime to the beagle dog. | An apparatus and novel method is described for administration of well-characterized inhalation aerosols, under strictly controlled respiratory regimes, direct to the respiratory tract (RT) of the beagle dog by positive-pressure ventilation. The method enables the study of systemic absorption kinetics of compounds deliv... | ['Absorption', 'Aerosols', 'Animals', 'Dogs', 'Fluorescein', 'Fluoresceins', 'Kinetics', 'Male', 'Particle Size', 'Positive-Pressure Respiration', 'Time Factors'] | 3,906,083 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['D20.280.055', 'D26.255.165.055'], ['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['D02.455.426.779.347.390', 'D03.633.300.953.275.390', 'D04.711.347.390'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['G01.374.661', 'G... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitation of homoharringtonine in plasma by high-performance liquid chromatography with amperometric detection. | A high-performance liquid chromatographic procedure was developed for the quantitation of homoharringtonine in plasma. Harringtonine was used as an internal standard, and 1 ml of sample was required. The single-step extraction with dichloromethane resulted in almost 100% recovery for homoharringtonine and harringtonine... | ['Alkaloids', 'Antineoplastic Agents, Phytogenic', 'Chemical Phenomena', 'Chemistry', 'Chromatography, High Pressure Liquid', 'Electrochemistry', 'Harringtonines', 'Homoharringtonine', 'Humans', 'Leukemia', 'Oxidation-Reduction'] | 2,592,509 | [['D03.132'], ['D27.505.954.248.179'], ['G02'], ['H01.181'], ['E05.196.181.400.300'], ['H01.181.529.307'], ['D03.132.420', 'D03.633.100.079.533', 'D03.633.400.624'], ['D03.132.420.500', 'D03.633.100.079.533.500', 'D03.633.400.624.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337'], ['G02.700', 'G03.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Stressful life events and minor psychiatric disorders: an estimate of the population attributable fraction in a Brazilian community-based study. | OBJECTIVE: A population-based survey was conducted in Pelotas, southern Brazil, to assess the specific and the combined contribution of life events and socioeconomic factors on the overall prevalence of minor psychiatric disorders (MPD).METHODS: The study covered a representative sample of the population aged fifteen y... | ['Adolescent', 'Adult', 'Brazil', 'Female', 'Humans', 'Life Change Events', 'Male', 'Mental Disorders', 'Middle Aged', 'Stress, Psychological'] | 8,877,488 | [['M01.060.057'], ['M01.060.116'], ['Z01.107.757.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458.410'], ['F03'], ['M01.060.116.630'], ['F01.145.126.990', 'F02.830.900']] | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Effectiveness of tapentadol prolonged release for the management of painful mucositis in head and neck cancers during intensity modulated radiation therapy. | PURPOSE: To evaluate the effectiveness and tolerability profile of tapentadol prolonged release (PR) in a cohort of head and neck cancer (HNC) patients affected by background pain due to painful mucositis during intensity modulated radiation therapy with or without cisplatin with definitive and adjuvant intent.MATERIAL... | ['Adult', 'Aged', 'Aged, 80 and over', 'Chronic Pain', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Male', 'Middle Aged', 'Mucositis', 'Phenols', 'Radiotherapy, Intensity-Modulated', 'Retrospective Studies', 'Tapentadol'] | 27,448,104 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.888.592.612.274'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C06.405.205.798', 'C07.465.584'], ['D02.455.426.559.389.657'], ['E02.815.635.700.700', 'L01.313.500.750.100.710.600.550.700'], ['E05.318.372.5... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Ultrasound and cone beam CT fusion for liver ablation: technical note. | PURPOSE: To assess the feasibility of fusion imaging between intraprocedural ultrasound (US) and contrast-enhanced cone-beam CT (CBCT) for small (< 2 cm) hepatocellular carcinoma (HCC).MATERIALS AND METHODS: Six patients (five males, one female, age range 58-80, mean 69 years), with small (mean diameter 16.8 mm) HCC po... | ['Aged', 'Aged, 80 and over', 'Catheter Ablation', 'Cone-Beam Computed Tomography', 'Female', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Retrospective Studies', 'Ultrasonography'] | 30,204,007 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.808.750.500', 'E04.014.760.500'], ['E01.370.350.700.810.810.490', 'E01.370.350.825.810.810.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hospital use of antipsychotic agents in 1989 and 1993: stable dosing with decreased length of stay. | OBJECTIVE: This study evaluated recent and current use of antipsychotics by psychiatric inpatients.METHOD: Computer-based hospital pharmacy records identified prescriptions for antipsychotics in 1993. Medical records were reviewed to verify prescription and clinical data, and these were compared with similar data from ... | ['Adult', 'Age Factors', 'Anticonvulsants', 'Antipsychotic Agents', 'Clozapine', 'Drug Administration Schedule', 'Drug Prescriptions', 'Drug Therapy, Combination', 'Drug Utilization', 'Female', 'Hospitalization', 'Humans', 'Length of Stay', 'Lithium', 'Male', 'Mental Disorders', 'Pharmacy Service, Hospital'] | 7,793,440 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['D27.505.954.427.080'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['D03.633.300.240.220'], ['E02.319.283'], ['E02.319.307', 'N02.421.668.778.500'], ['E02.319.310'], ['N04.452.706.477'], ['E02.760.400', 'N02.421.5... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A mutation within exon 14 of the TGFBI (BIGH3) gene on chromosome 5q31 causes an asymmetric, late-onset form of lattice corneal dystrophy. | PURPOSE: Two forms of autosomal-dominant lattice corneal dystrophy (LCD), types I and IIIA, have previously been shown to be caused by different mutations within the transforming growth factor, beta-induced (TGFBI) gene. A clinical and molecular analysis of three unrelated kindreds with a clinically distinct late-onset... | ['Adult', 'Age of Onset', 'Chromosomes, Human, Pair 5', 'Cornea', 'Corneal Dystrophies, Hereditary', 'DNA', 'DNA Mutational Analysis', 'DNA Primers', 'Exons', 'Extracellular Matrix Proteins', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Proteins', 'Pedigree', 'Point Mutation', 'Polymerase Chain Reaction', 'Poly... | 10,328,397 | [['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['A11.284.187.520.300.280.290', 'G05.360.162.520.300.280.290'], ['A09.371.060.217'], ['C11.204.236', 'C11.270.162', 'C16.320.290.162'], ['D13.444.308'], ['E05.393.760.700.300'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.360.340.02... | ['Named Groups [M]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of 3D TOF-MRA and 3D CE-MRA at 3T for imaging of intracranial aneurysms. | PURPOSE: To compare 3T elliptical-centric CE MRA with 3T TOF MRA for the detection and characterization of unruptured intracranial aneurysms (UIAs), by using digital subtracted angiography (DSA) as reference.MATERIALS AND METHODS: Twenty-nine patients (12 male, 17 female; mean age: 62 years) with 41 aneurysms (34 saccu... | ['Adult', 'Aged', 'Algorithms', 'Female', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Intracranial Aneurysm', 'Magnetic Resonance Angiography', 'Male', 'Middle Aged', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 24,103,356 | [['M01.060.116'], ['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.400', 'L01.224.308.410'], ['C10.228.140.300.510.600', 'C14.907.055.635', 'C14.9... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Family planning and parenthood needs of women with severe mental illness: clinicians' perspective. | Family planning and parenthood are important issues for women with severe and persistent mental illness (SPMI). The role of adult mental health clinicians with regard to these issues has been under investigated. Clinicians treating patients with SPMI at a large community health center completed survey forms on 419 wome... | ['Adult', 'Aged', 'Aged, 80 and over', 'Catchment Area, Health', 'Community Mental Health Services', 'Family Planning Services', 'Female', 'Health Personnel', 'Health Services Needs and Demand', 'Humans', 'Mental Disorders', 'Middle Aged', 'Parenting', 'Pennsylvania', 'Severity of Illness Index'] | 10,452,703 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N01.224.791.200', 'N03.349.650.095', 'N06.850.505.400.800.200'], ['F04.408.307', 'N02.421.143.183', 'N02.421.461.232'], ['N02.421.143.401', 'N02.421.800.249'], ['M01.526.485', 'N02.360'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Changes in bone mass and bone turnover following distal forearm fracture. | Bone loss occurs close to a fracture and is associated with increased bone turnover. Fracture healing itself results in increased markers of bone turnover. But the exact patterns of these changes after different fractures are unclear. We aimed to investigate the changes in bone density and biochemical markers following... | ['Acid Phosphatase', 'Aged', 'Alkaline Phosphatase', 'Amino Acids', 'Analysis of Variance', 'Area Under Curve', 'Biomarkers', 'Bone Density', "Colles' Fracture", 'Female', 'Fingers', 'Humans', 'Isoenzymes', 'Middle Aged', 'Osteocalcin', 'Osteoporosis', 'Peptide Fragments', 'Procollagen', 'Reflex Sympathetic Dystrophy',... | 10,591,838 | [['D08.811.277.352.650.025'], ['M01.060.116.100'], ['D08.811.277.352.650.035'], ['D12.125'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D23.101'], ['G11.427.100'], ['C05.550.518.336.500', 'C26.289.336.500', 'C26.404.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effort-reward imbalance at work is predicted by temporal and energetic characteristics of behavior: a population-based study. | OBJECTIVE: Personality dispositions may influence perceptions of work stress. The paper examines the relationship between temperament in terms of Strelau’s Regulative Theory of Temperament and the effort-reward imbalance and its components.MATERIAL AND METHODS: There were 890 participants (360 men) aged 37.9 years on a... | ['Adult', 'Arousal', 'Character', 'Female', 'Humans', 'Male', 'Middle Aged', 'Perception', 'Salaries and Fringe Benefits', 'Surveys and Questionnaires', 'Temperament', 'Workload'] | 23,959,687 | [['M01.060.116'], ['F02.830.104', 'G11.561.035'], ['F01.752.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.463.593'], ['N01.824.417.700', 'N04.452.677.800'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['F01.752.898'], ['I03.946.225.500', 'N04.452.677.650.500']... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Developing and Implementing Major League Baseball's Health and Injury Tracking System. | In 2010, Major League Baseball and the Major League Baseball Players Association reached an agreement regarding the development and implementation of an electronic medical record system and a new league-wide injury surveillance system. The systems were developed to create a more efficient method to track medical histor... | ['Baseball', 'Epidemiologic Studies', 'Humans', 'Male', 'Occupational Injuries', 'Risk Management', 'Sentinel Surveillance', 'United States'] | 26,874,305 | [['I03.450.642.845.110'], ['E05.318.372.500', 'N05.715.360.330.500', 'N06.850.520.450.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.716'], ['N03.219.463.800', 'N04.452.871'], ['E05.318.308.980.438.700.650', 'E05.318.650', 'N05.715.360.300.800.438.625.650', 'N06.850.520.308.980.438.700.650', 'N06.850.520... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
The association of urinary tract infection with sexual intercourse. | To assess the significance of sexual intercourse as a precipitating factor of urinary tract infection in premenopausal women with recurrent infection, 15 patients were monitored with daily dipslides and calendar recording of intercourse episodes after antimicrobial prophylaxis was discontinued. Eleven patients experien... | ['Adult', 'Anti-Infective Agents, Urinary', 'Coitus', 'Female', 'Humans', 'Menstruation', 'Middle Aged', 'Urinary Tract Infections'] | 7,130,747 | [['M01.060.116'], ['D27.505.954.122.237', 'D27.505.954.613.056'], ['F01.145.802.188', 'G08.686.784.041'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.605.428'], ['M01.060.116.630'], ['C01.915', 'C12.777.892', 'C13.351.968.892']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bioinformatics Pipeline for Transcriptome Sequencing Analysis. | The development of High Throughput Sequencing (HTS) for RNA profiling (RNA-seq) has shed light on the diversity of transcriptomes. While RNA-seq is becoming a de facto standard for monitoring the population of expressed transcripts in a given condition at a specific time, processing the huge amount of data it generates... | ['Computational Biology', 'Gene Expression Profiling', 'High-Throughput Nucleotide Sequencing', 'Humans', 'K562 Cells', 'Sequence Analysis, RNA', 'Workflow'] | 27,662,878 | [['H01.158.273.180', 'L01.313.124'], ['E05.393.332'], ['E05.393.760.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.510', 'A11.251.860.180.510', 'A11.443.240.497.480'], ['E05.393.760.710'], ['L01.906.893']] | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of Posture and Body Mass Index on Body Girth Assessment. | BACKGROUND: The present study aimed to evaluate the effect of posture on body girth assessment among hospitalized adults and older adults. We further explored the influence of body mass index (BMI) on this effect.MATERIALS AND METHODS: A cross-sectional study was conducted among hospitalized adult patients. Arm, waist,... | ['Aged', 'Anthropometry', 'Body Composition', 'Body Mass Index', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Posture'] | 26,888,857 | [['M01.060.116.100'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.