Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Comparison of artery-ligating and artery-preserving varicocelectomy: effect on post-operative spermatogenesis. | To evaluate the effects of ligature of the internal spermatic artery at varicocelectomy on fertility, we conducted a prospective randomized study for comparison of two surgical methods (artery-ligated and artery-preserved). A total of 66 infertile patients with palpable varicocele was randomly assigned to an artery-lig... | ['Adult', 'Arteries', 'Female', 'Humans', 'Infertility, Male', 'Ligation', 'Male', 'Pregnancy', 'Spermatogenesis', 'Testis', 'Varicocele'] | 7,755,188 | [['M01.060.116'], ['A07.015.114'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365.700'], ['E04.426'], ['G08.686.784.769'], ['G04.152.650.624', 'G08.686.784.310.760'], ['A05.360.444.849', 'A05.360.576.782', 'A06.300.312.782'], ['C12.294.936', 'C14.907.903']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Renal artery thrombosis: a cause of reversible acute renal failure. | Acute renal failure can be produced by interruption of the arterial blood supply. We describe a case of acute renal failure that developed owing to thrombosis of the renal artery of the only functioning kidney. This thrombosis occurred in an artery that was stenosed probably by an arteriosclerotic plaque. The blood flo... | ['Acute Kidney Injury', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Renal Artery Obstruction', 'Renal Circulation', 'Thrombosis'] | 7,154,188 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700'], ['C12.777.419.775', 'C13.351.968.419.775', 'C14.907.137.727'], ['G08.852.725', 'G09.330.100.812'], ['C14.907.355.830']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Unexpected up-regulation of gene expression by cyclosporin A and FK-506 in a T-cell lymphoma: both immunosuppressants augment Ly-6E antigen induction by interferon-gamma in the presence of ionomycin. | Cyclosporin A (CsA) and FK-506 inhibit lymphokine gene activation in T-cells. In the present study, we investigated the effects of these immunosuppressants on the regulation of a non-lymphokine molecule, the Ly-6E surface antigen, in the YAC-1 T-cell lymphoma. These cells do not normally express Ly-6E mRNA or Ly-6E sur... | ['Animals', 'Antigens, Ly', 'Cyclosporine', 'Gene Expression Regulation, Neoplastic', 'In Vitro Techniques', 'Interferon-gamma', 'Ionomycin', 'Lymphoma, T-Cell', 'Mice', 'Mice, Inbred BALB C', 'T-Lymphocytes', 'Tacrolimus', 'Transcriptional Activation', 'Tumor Cells, Cultured', 'Up-Regulation'] | 1,726,093 | [['B01.050'], ['D23.050.301.264.920', 'D23.101.100.920'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['G05.308.370'], ['E05.481'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615.350'], ['D10.251.355.39... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Load cycling enhances bioactivity at the resin-dentin interface. | OBJECTIVES: The purpose of this study was to evaluate if mechanical loading promotes bioactivity at the resin interface after bonding with three different adhesive approaches.METHODS: Dentin surfaces were subjected to three different treatments: demineralisation by (1) 37% phosphoric acid (PA) followed by application o... | ['Acid Etching, Dental', 'Adult', 'Dentin', 'Humans', 'In Vitro Techniques', 'Materials Testing', 'Microscopy, Atomic Force', 'Microscopy, Confocal', 'Resin Cements', 'Spectrum Analysis, Raman', 'Young Adult'] | 24,630,703 | [['E06.931.475.111'], ['M01.060.116'], ['A14.549.167.900.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['E05.570'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['E01.370.350.515.395', 'E05.595.395'], ['D05.750.716.822.730', 'D25.339.291.750', 'D25.720.716.822.730', 'J01.637.051.339.291.750', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Microwave-assisted one-pot synthesis of 1-indanones from arenes and alpha,beta-unsaturated acyl chlorides. | A series of 1-indanones were synthesized in good yields via tandem Friedel-Crafts acylation and Nazarov cyclization of arenes and alpha,beta-unsaturated acyl chlorides in the presence of aluminum chloride under microwave irradiation. | ['Chlorides', 'Indans', 'Microwaves', 'Molecular Structure'] | 16,709,078 | [['D01.210.450.150', 'D01.248.497.158.215'], ['D02.455.426.559.847.486.487', 'D04.615.486.487'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['G02.111.570', 'G02.466']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Orthostatic hypotension and cerebral blood flow velocity in the rehabilitation of stroke patients. | The objective of this study was to investigate the results of transcranial Doppler monitoring during tilt table tests in stroke patients with and without orthostatic hypotension. In stroke patients without orthostatic hypotension, the mean flow velocity was almost similar in both middle cerebral arteries and was stable... | ['Acute Disease', 'Blood Flow Velocity', 'Brain Ischemia', 'Cerebrovascular Circulation', 'Female', 'Humans', 'Hypotension, Orthostatic', 'Male', 'Middle Aged', 'Middle Cerebral Artery', 'Oxygen', 'Prospective Studies', 'Stroke', 'Stroke Rehabilitation', 'Tilt-Table Test', 'Ultrasonography, Doppler, Transcranial'] | 17,106,353 | [['C23.550.291.125'], ['E01.370.370.130', 'G09.330.380.630.080'], ['C10.228.140.300.150', 'C14.907.253.092'], ['G09.330.100.159'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.177.575.600.450', 'C14.907.514.482'], ['M01.060.116.630'], ['A07.015.114.228.550'], ['D01.268.185.550', 'D01.362.670'], ['E05.318.372.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Serum adipokine levels modified by donepezil treatment in Alzheimer's disease. | Neurotransmitter enhancement therapy with acetylcholinesterase inhibitors (AChEIs) is a clinically proven approach for patients with Alzheimer's disease (AD). Donepezil is one of the three currently approved AChEIs for treating AD symptoms delaying the decline in cognitive function. In addition to cholinergic hypofunct... | ['Adipokines', 'Adiponectin', 'Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Cholinesterase Inhibitors', 'Cognition', 'Donepezil', 'Female', 'Humans', 'Indans', 'Male', 'Neuropsychological Tests', 'Piperidines', 'Prospective Studies', 'Time Factors'] | 23,979,024 | [['D06.472.699.042', 'D12.644.276.024', 'D12.644.548.011', 'D12.776.467.024', 'D23.529.024'], ['D06.472.699.042.249', 'D12.644.276.024.249', 'D12.644.548.011.249', 'D12.776.467.024.249', 'D23.529.024.249'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D2... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Naturally safe: Cellular noise for document security. | Modern document protection relies on the simultaneous combination of many optical features with micron and submicron structures, whose complexity is the main obstacle for unauthorized copying. In that sense, documents are best protected by the diffractive optical elements generated lithographically and mass-produced by... | ['Animals', 'Biomimetics', 'Butterflies', 'Documentation', 'Optical Phenomena', 'Safety', 'Wings, Animal'] | 31,452,335 | [['B01.050'], ['H01.158.550.100', 'J01.897.120.100'], ['B01.050.500.131.617.720.500.500.937.200'], ['L01.453.245'], ['G01.590'], ['N06.850.135.060.075'], ['A13.395.823']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Parity effects on maternal behaviour are not related to circulating oestradiol concentrations in two breeds of sheep. | Primiparous females of many species, including the sheep, do not show as competent maternal behaviour as multiparous mothers. In this study we investigated whether circulating concentrations of oestradiol might be related to this response, since breed differences in oestradiol concentrations have been shown to correlat... | ['Animals', 'Estradiol', 'Female', 'Maternal Behavior', 'Parity', 'Practice, Psychological', 'Pregnancy', 'Progesterone', 'Sheep', 'Species Specificity'] | 17,884,115 | [['B01.050'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['F01.829.263.370.215'], ['G08.686.677', 'G08.686.784.769.472', 'N06.850.490.812.600'], ['F02.463.425.674'], ['G08.686.784.769'], ['D04.210.500.745.745.654.829', 'D06.472.334.734.623', 'D06.472.334.851.687.750'], ['B01.050.150.900.649.313.500.380.791... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The voltage dependent anion selective channel family in Drosophila melanogaster. | VDACs (voltage-dependent anion-selective channels) or mitochondrial PORINS are transmembrane proteins forming pores in the outer membrane. In eukaryotic genomes multiple genes coding for VDAC homologues have been discovered, but the functional meaning of this gene redundancy is unknown. In Drosophila melanogasterthree ... | ['Amino Acid Sequence', 'Animals', 'Computational Biology', 'Drosophila Proteins', 'Drosophila melanogaster', 'Immunoblotting', 'Immunoprecipitation', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Protein Structure, Secondary', 'Sequence Homology, Amino Acid', 'Voltage-Dependent Anion Channel 1', 'Voltage-De... | 19,192,627 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['H01.158.273.180', 'L01.313.124'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['E05.478.566.320', 'E05.601.470.320'], ['E05.196.150.639', 'E05.478.605'], ['L01.453.245.667'], ['E05.393.620.500'], ['G02.111.570.820.709.600'], [... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Neuroprotective evaluation of extract of ginger (Zingiber officinale) root in monosodium glutamate-induced toxicity in different brain areas male albino rats. | In this study, the neuroprotective effect of the extract of ginger (Zingiber officinale) was investigated against MSG-induced neurotoxicity of male albino rat. The daily dose (4 mg kg(-1) b.wt.) i.p. injection of pure monosodium glutamate (MSG) for 30 days and subsequent withdrawal caused a significant decrease in epin... | ['Animals', 'Brain', 'Ginger', 'Humans', 'Male', 'Neuroprotective Agents', 'Plant Roots', 'Rats', 'Sodium Glutamate'] | 19,579,948 | [['B01.050'], ['A08.186.211'], ['B01.650.940.800.575.912.250.618.937.900.444'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.706.548', 'D27.505.954.427.575'], ['A18.400'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.125.067.625.349.850', 'D12.125.119.409.349.575']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA). | OBJECTIVES: The aims of the Online Latin American Survey of Anaphylaxis (OLASA) were to identify the main clinical manifestations, triggers, and treatments of severe allergic reactions in patients who were seen by allergists from July 2008 to June 2010 in 15 Latin American countries and Portugal (n =634).RESULTS: Of al... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Anaphylaxis', 'Anti-Allergic Agents', 'Child', 'Child, Preschool', 'Epinephrine', 'Female', 'Health Surveys', 'Humans', 'Infant', 'Latin America', 'Male', 'Middle Aged', 'Portugal', 'Time Factors', 'Treatment Outcome', 'Young Adult'] | 21,808,856 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C20.543.480.099'], ['D27.505.954.016'], ['M01.060.406'], ['M01.060.406.448'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.55... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Cholesterol: a useful parameter for distinguishing between pleural exudates and transudates. | Previously established criteria were used to classify 253 pleural effusions as transudates (65 cases), neoplastic exudates (67 cases), tuberculous exudates (65 cases), or miscellaneous exudate (56 cases). The parameters pleural LDH (PLDH), pleural LDH/serum LDH ratio (P/SLDH), and pleural protein/serum protein ratio (P... | ['Adult', 'Aged', 'Cholesterol', 'Diagnosis, Differential', 'Exudates and Transudates', 'Female', 'Humans', 'L-Lactate Dehydrogenase', 'Male', 'Middle Aged', 'Pleural Effusion', 'Pleural Effusion, Malignant', 'Sensitivity and Specificity', 'Tuberculosis, Pleural'] | 2,019,164 | [['M01.060.116'], ['M01.060.116.100'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['E01.171'], ['A12.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['M01.060.116.630'], ['C08.528.652'], ['C04.588.894.797.640.700', 'C08.528.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of k-space-weighted image contrast and ultrasound focus size on the accuracy of proton resonance frequency thermometry. | PURPOSE: To construct a predictive model that describes how the duration and symmetry of a k-space-weighted image contrast (KWIC) window affects the temporal resolution of differently sized ultrasound foci when using a pseudo-golden angle stack-of-stars acquisition.METHODS: We performed a modulation analysis of proton ... | ['Acoustics', 'Algorithms', 'Artifacts', 'Breast', 'Computer Simulation', 'Diagnostic Imaging', 'Female', 'Fourier Analysis', 'Humans', 'Image Interpretation, Computer-Assisted', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Magnetic Resonance Imaging', 'Normal Distribution', 'Phantoms, Imaging'... | 30,058,224 | [['H01.671.031'], ['G17.035', 'L01.224.050'], ['E05.047'], ['A01.236'], ['L01.224.160'], ['E01.370.350'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['L01.224.308'], ['E01.370.350.400', 'L01.224.308.410']... | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Mutagenicity of natural anthraquinones from Rubia tinctorum in the Drosophila wing spot test. | Mutagenicity of anthraquinone aglycones from Rubia tinctorum L. (Rubiaceae) was examined using the somatic mutation and recombination test in Drosophila melanogaster. Larvae heterozygous for recessive wing trichome mutations, multiple wing hairs (mwh), and flare (flr3) were exposed to test compounds and wings of emerge... | ['Animals', 'Anthraquinones', 'Drosophila melanogaster', 'Larva', 'Molecular Structure', 'Mutagenicity Tests', 'Mutagens', 'Plant Roots', 'Plants, Medicinal', 'Pyrans', 'Recombination, Genetic', 'Rubiaceae', 'Wings, Animal'] | 11,301,857 | [['B01.050'], ['D02.455.426.559.847.117.159', 'D02.806.100', 'D04.615.117.159'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G02.111.570', 'G02.466'], ['E05.393.560', 'E05.940.560'], ['D27.888.569.468'], ['A18.400'], ['B01.650.560'], ['D03.383.663'], ['G05.728'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
How useful is the Mantoux test in the diagnosis of doubtful cases of cutaneous tuberculosis? | BACKGROUND: Diagnostic tests are critical to management when the clinical picture is unclear. We analyzed the records of patients in whom the initial diagnosis of cutaneous tuberculosis was doubtful to evaluate the utility of the Mantoux test in this setting.MATERIALS AND METHODS: Of 375 patients with cutaneous tubercu... | ['Adolescent', 'Adult', 'Aged', 'Antitubercular Agents', 'Biopsy', 'Child', 'Child, Preschool', 'Ethambutol', 'Female', 'Humans', 'Isoniazid', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Pyrazinamide', 'ROC Curve', 'Rifampin', 'Tuberculin Test', 'Tuberculosis, Cutaneous', 'Young Adult'] | 22,004,492 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.085.255'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['M01.060.406'], ['M01.060.406.448'], ['D02.092.782.258.368.265'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of unstable shoulders by computed tomography. A preliminary study. | Three patients who had various types of glenohumeral joint instability, and in whom computed tomography (CT) was utilized as an additional diagnostic modality, are presented. In two of the three patients, routine radiography supplemented with special views documented the presence of a Hill-Sachs lesion; in the third, a... | ['Adult', 'Humans', 'Humerus', 'Male', 'Recurrence', 'Shoulder Dislocation', 'Tomography, X-Ray Computed'] | 7,114,347 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.087.090.400'], ['C23.550.291.937'], ['C05.550.518.750', 'C26.289.750', 'C26.803.125'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multiple encephalitogenic peptides of myelin basic protein in A.CA mice. | Experimental allergic encephalomyelitis (EAE) is an autoimmune disease of the central nervous system. It is mediated by T cells and is an animal model for the human disease multiple sclerosis. In most mouse strains that are susceptible to induction of EAE by myelin basic protein, a dominant peptide of myelin basic prot... | ['Amino Acid Sequence', 'Animals', 'Encephalomyelitis, Autoimmune, Experimental', 'Epitopes', 'Immunization, Passive', 'Lymph Nodes', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred A', 'Molecular Sequence Data', 'Myelin Basic Protein', 'Peptides', 'T-Lymphocytes'] | 7,680,964 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.314.350.250', 'C20.111.258.625.300', 'E05.598.500.500.500'], ['D23.050.550'], ['E02.095.465.425.400.330', 'E05.478.550.520'], ['A10.549.400', 'A15.382.520.604.412'], ['E01.370.225.812.482', 'E05.200.812.482', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Tinea nigra: treatment with topical ketoconazole. | Tinea nigra is a relatively uncommon fungal infection presenting as a pigmented macule of the palms or soles. Since the lesion can easily mimic a melanocytic process, it is important to recognize the infection before recommending unnecessary surgical procedures. A case of tinea nigra that responded to treatment with to... | ['Administration, Topical', 'Animals', 'Dermatomycoses', 'Exophiala', 'Female', 'Foot Dermatoses', 'Humans', 'Ketoconazole', 'Middle Aged'] | 8,261,805 | [['E02.319.267.120'], ['B01.050'], ['C01.150.703.302', 'C01.800.200', 'C17.800.838.208'], ['B01.300.107.366', 'B01.300.381.355'], ['C17.800.321.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.606.560'], ['M01.060.116.630']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mixed-model reanalysis of primate data suggests tissue and species biases in oligonucleotide-based gene expression profiles. | An emerging issue in evolutionary genetics is whether it is possible to use gene expression profiling to identify genes that are associated with morphological, physiological, or behavioral divergence between species and whether these genes have undergone positive selection. Some of these questions were addressed in a r... | ['Animals', 'Brain', 'Gene Expression', 'Gene Expression Profiling', 'Genetics, Medical', 'Humans', 'Liver', 'Mice', 'Organ Specificity', 'Pan troglodytes', 'Pongo pygmaeus', 'RNA, Messenger', 'Species Specificity'] | 14,573,485 | [['B01.050'], ['A08.186.211'], ['G05.297'], ['E05.393.332'], ['H01.158.273.343.385.500', 'H02.403.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['G07.650'], ['B01.050.150.900.649.313.988.400.112.400.620'], ['B01.050.150.900.649.313.988.400.112.400.635.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
An unusual cause of facial pain: malignant change in a calcified pleomorphic adenoma in the deep lobe of the parotid gland. | We describe a case of a malignant change in a calcified pleomorphic adenoma of the deep lobe of the parotid gland in a patient whose initial symptom was facial pain. We also discuss the relative merits of the different imaging modalities as they apply to the parotid gland. | ['Adenoma, Pleomorphic', 'Calcinosis', 'Facial Pain', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Middle Aged', 'Parotid Neoplasms', 'Tomography, X-Ray Computed'] | 14,503,101 | [['C04.557.435.090', 'C04.557.470.035.155'], ['C18.452.174.130'], ['C23.888.592.612.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C04.588.443.591.824.695', 'C07.465.530.824.695', 'C07.465.815.470.770', 'C07.465.815.718.589'], ['E01.370.350.350.810', 'E01.370.350... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Participation of liver progenitor cells in liver regeneration: lack of evidence in the AAF/PH rat model. | When hepatocyte proliferation is impaired, liver progenitor cells (LPC) are activated to participate in liver regeneration. We used the 2-acetaminofluorene/partial hepatectomy (AAF/PH) model to evaluate the contribution of LPC to liver cell replacement and function restoration. Fischer rats subjected to AAF/PH (or PH a... | ['2-Acetylaminofluorene', 'AC133 Antigen', 'Animals', 'Antigens, CD', 'Glycoproteins', 'Hepatectomy', 'Keratin-19', 'Liver', 'Liver Regeneration', 'Male', 'Models, Animal', 'Peptides', 'Rats', 'Rats, Inbred F344', 'Stem Cells'] | 21,912,377 | [['D02.065.064.150', 'D02.241.081.018.110.080', 'D02.455.426.559.847.389.050', 'D04.615.389.050'], ['D12.776.395.550.007', 'D12.776.543.550.023'], ['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D09.400.430', 'D12.776.395'], ['E04.210.556'], ['D05.750.078.593.450.300.900', 'D12.776.220.475.450.300.900', 'D12... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Understanding rice plant resistance to the Brown Planthopper (Nilaparvata lugens): a proteomic approach. | Engineering and breeding resistant plant varieties are the most effective and environmentally friendly ways to control agricultural pests and improve crop performance. However, the mechanism of plant resistance to pests is poorly understood. Here we used a quantitative mass-spectrometry-based proteomic approach for com... | ['Animals', 'Cyclopentanes', 'Gene Expression Profiling', 'Gene Expression Regulation, Plant', 'Hemiptera', 'Mass Spectrometry', 'Oryza', 'Oxidative Stress', 'Oxylipins', 'Plant Leaves', 'Plant Proteins'] | 19,405,033 | [['B01.050'], ['D02.455.426.392.368.450'], ['E05.393.332'], ['G05.308.375'], ['B01.050.500.131.617.412'], ['E05.196.566'], ['B01.650.940.800.575.912.250.822.616'], ['G03.673', 'G07.775.750'], ['D10.251.355.645'], ['A18.024.812'], ['D12.776.765']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
HLA-B13 and chronic calcific pancreatitis. | In view of a possible role of genetic factors in the etiology of chronic calcific pancreatitis, we undertook a study of the frequency of HLA antigens in this disease. Sixty-four patients with chronic calcific pancreatitis were typed for the HLA-A, -B and -C loci. Fourteen of these 64 patients (21.9%) were found to have... | ['Adolescent', 'Adult', 'Aged', 'Calcinosis', 'Chronic Disease', 'Female', 'HLA Antigens', 'HLA-B Antigens', 'Histocompatibility Testing', 'Humans', 'Male', 'Middle Aged', 'Pancreatitis'] | 6,951,694 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C18.452.174.130'], ['C23.550.291.500'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['D12.776.395.550.489.500', 'D12.776.543.550.439.500', 'D23.050.301.500.100.500', 'D23.050.301.500.450.380', 'D23.050.705.552.100.500', 'D23.050.705.552.450.380'], ['E01.370.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The clinical significance of fibrinogen plasma levels in patients with diffuse large B cell lymphoma. | BACKGROUND: Fibrinogen plays a crucial role in the pathophysiology of tumour cell growth, invasion and metastasis. The aim of this study was to evaluate the prognostic significance of pretreatment plasma fibrinogen levels in patients with diffuse large B cell lymphoma (DLBCL) METHODS: Data from 372 patients with DLBCL,... | ['Adult', 'Aged', 'Area Under Curve', 'Biomarkers, Tumor', 'Disease-Free Survival', 'Female', 'Fibrinogen', 'Humans', 'Kaplan-Meier Estimate', 'Lymphoma, Large B-Cell, Diffuse', 'Male', 'Middle Aged', 'Prognosis', 'Proportional Hazards Models', 'ROC Curve', 'Retrospective Studies'] | 26,644,520 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D23.101.140'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['D12.776.124.050.250', 'D12.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
POLR1D promotes colorectal cancer progression and predicts poor prognosis of patients. | RNA polymerase I subunit D (POLR1D), which is involved in synthesis of ribosomal RNA precursors and small RNAs, has been shown to be overexpressed in several human cancer types. Nevertheless, the role of POLR1D in the progression of colorectal cancer (CRC) remains unknown. The following study aimed to investigate the r... | ['Adenocarcinoma', 'Aged', 'Animals', 'Apoptosis', 'Biomarkers, Tumor', 'Cell Movement', 'Cell Proliferation', 'Colorectal Neoplasms', 'DNA-Directed RNA Polymerases', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lymphatic Metastasis', 'Male', 'Mice', 'Mice, ... | 30,582,221 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['B01.050'], ['G04.146.954.035'], ['D23.101.140'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['D08.... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Risk factors for infection and evaluation of Sepsis-3 in patients with trauma. | BACKGROUND: We aim to examine the risk factors associated with infection in trauma patients and the Sepsis-3 definition.METHODS: This was a retrospective cohort study of adult trauma patients admitted to a Level I trauma center between January 2014 and January 2016.RESULTS: A total of 1499 trauma patients met inclusion... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Hospital Mortality', 'Humans', 'Injury Severity Score', 'Logistic Models', 'Male', 'Middle Aged', 'Organ Dysfunction Scores', 'Prognosis', 'Retrospective Studies', 'Risk Factors', 'Sepsis', 'Wounds and Injuries', 'Young Adult'] | 30,885,453 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.940.968.875.500', 'E05.944.600', 'N04.452.859.564.800.500', 'N... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tandem mass spectrometry for the direct assay of enzymes in dried blood spots: application to newborn screening for mucopolysaccharidosis II (Hunter disease). | BACKGROUND: A treatment for mucopolysaccharidosis II (Hunter syndrome) has recently become available. Therefore, we developed a high-throughput assay method appropriate for newborn screening for the relevant enzyme, iduronate 2-sulfatase.METHODS: We synthesized a new iduronate 2-sulfatase substrate that can be used to ... | ['Blood Specimen Collection', 'Clinical Enzyme Tests', 'Glycoproteins', 'Humans', 'Infant, Newborn', 'Mass Spectrometry', 'Mucopolysaccharidosis II', 'Neonatal Screening'] | 17,082,248 | [['E01.370.225.998.110', 'E04.665.150', 'E05.200.998.110'], ['E01.370.225.124.200', 'E05.196.427.200', 'E05.200.124.200'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E05.196.566'], ['C10.597.606.360.455.750', 'C16.320.322.500.750', 'C16.320.400.525.750', 'C16... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Insecticide resistance monitoring and correlation analysis of insecticides in field populations of the brown planthopper Nilaparvata lugens (st?l) in China 2012-2014. | The brown planthopper is a serious rice pest in China. Chemical insecticides have been considered a satisfactory means of controlling the brown planthopper. In the present study, we determined the susceptibility of twenty-one populations of Nilaparvata lugens to eleven insecticides by a rice-stem dipping method from 20... | ['Animals', 'Carbamates', 'China', 'Chlorpyrifos', 'Guanidines', 'Hemiptera', 'Imidazoles', 'Insecticide Resistance', 'Insecticides', 'Neonicotinoids', 'Nitro Compounds', 'Oxazines', 'Pyrazoles', 'Pyrethrins', 'Pyridines', 'Thiadiazines', 'Thiamethoxam', 'Thiazines', 'Thiazoles'] | 27,521,908 | [['B01.050'], ['D02.241.081.251'], ['Z01.252.474.164'], ['D02.705.400.625.100', 'D02.705.539.345.100', 'D02.886.300.692.100'], ['D02.078.370'], ['B01.050.500.131.617.412'], ['D03.383.129.308'], ['G07.690.773.984.491'], ['D27.720.031.700.491', 'D27.888.723.491'], ['D03.383.464'], ['D02.640'], ['D03.383.533'], ['D03.383.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Use of extended right grafts from in situ split livers in adult liver transplantation: a comparison with whole-liver transplants. | INTRODUCTION: We report our experience of in situ split-liver transplantation (SLT) for adult patients and compare the results with those achieved with whole-liver transplantation (WLT).METHOD: From November 1997 to December 2003, 109 liver transplantation were performed in 104 adult patients including 90 WLT (83%) and... | ['Adult', 'Aged', 'Child', 'Child, Preschool', 'Female', 'Health Care Rationing', 'Hemodynamics', 'Hepatectomy', 'Humans', 'Liver Diseases', 'Liver Function Tests', 'Liver Transplantation', 'Male', 'Middle Aged', 'Organ Size', 'Reoperation', 'Retrospective Studies', 'Tissue and Organ Harvesting', 'Treatment Outcome'] | 15,848,657 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['I01.261.750.500', 'N03.349.270', 'N05.300.430.375'], ['G09.330.380'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552'], ['E01.370.372.460'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Induction of a peptide with activity against a broad spectrum of pathogens in the Aedes aegypti salivary gland, following Infection with Dengue Virus. | The ultimate stage of the transmission of Dengue Virus (DENV) to man is strongly dependent on crosstalk between the virus and the immune system of its vector Aedes aegypti (Ae. aegypti). Infection of the mosquito's salivary glands by DENV is the final step prior to viral transmission. Therefore, in the present study, w... | ['Aedes', 'Animals', 'Cell Survival', 'Circular Dichroism', 'Dengue', 'Dengue Virus', 'Female', 'HEK293 Cells', 'Haplorhini', 'Host-Pathogen Interactions', 'Humans', 'Insect Proteins', 'Insect Vectors', 'Kidney', 'Peptide Biosynthesis', 'Salivary Glands'] | 21,249,175 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['G04.346'], ['E05.196.867.151'], ['C01.920.500.270', 'C01.925.081.270', 'C01.925.782.350.250.214', 'C01.925.782.417.214'], ['B04.820.578.344.350.270'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400'], ['G06.462', 'G16.52... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Expression of mouse membrane-associated prostaglandin E2 synthase-2 (mPGES-2) along the urogenital tract. | Prostaglandin E(2) (PGE(2)) is the most common prostanoid and has a variety of bioactivities including a crucial role in urogenital function. Multiple enzymes are involved in its biosynthesis. Among 3 PGE(2) terminal synthetic enzymes, membrane-associated PGE(2) synthase-2 (mPGES-2) is the most recently identified, and... | ['Animals', 'Base Sequence', 'Binding Sites', 'Chromosome Mapping', 'DNA, Complementary', 'Female', 'Gene Expression', 'Genitalia, Female', 'Genitalia, Male', 'Intramolecular Oxidoreductases', 'Male', 'Membranes', 'Mice', 'Mice, Inbred C57BL', 'Molecular Sequence Data', 'Promoter Regions, Genetic', 'Prostaglandin-E Syn... | 17,064,959 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['E05.393.183'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G05.297'], ['A05.360.319'], ['A05.360.444'], ['D08.811.399.475'], ['A10.615'], ['B01.050.150.900.649.313.992.635.505.500'], ['B0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparison of antimicrobial susceptibility patterns among coagulase-negative staphylococci. | Coagulase-negative staphylococci, identified as S. epidermidis, S. saprophyticus, S. haemolyticus, S. hominis, and S. warneri, were tested for susceptibility to a number of antimicrobial agents by disk agar diffusion and broth microdilution methods, S. warneri and S. saprophyticus were found to be the most susceptible,... | ['Anti-Bacterial Agents', 'Coagulase', 'Microbial Sensitivity Tests', 'Staphylococcus'] | 7,103,446 | [['D27.505.954.122.085'], ['D08.811.277.656.300.174', 'D12.776.097.181'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['B03.300.390.400.800.750', 'B03.353.500.750.750', 'B03.510.100.750.750', 'B03.510.400.790.750']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phenotype and genotype predictors of BMI variability among European adults. | BACKGROUND/OBJECTIVE: Obesity is a complex and multifactorial disease resulting from the interactions among genetics, metabolic, behavioral, sociocultural and environmental factors. In this sense, the aim of the present study was to identify phenotype and genotype variables that could be relevant determinants of body m... | ['Adult', 'Age Factors', 'Alpha-Ketoglutarate-Dependent Dioxygenase FTO', 'Apolipoproteins E', 'Body Mass Index', 'Europe', 'Exercise', 'Female', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Male', 'Middle Aged', 'PPAR alpha', 'PPAR gamma', 'Phenotype', 'Polymorphism, Singl... | 29,795,275 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['D08.811.074.062.968', 'D08.811.682.662.582.242', 'D08.811.682.690.416.139.992'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['Z01.542'], ['G11... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Electrochemical detection of catecholamine release using planar iridium oxide electrodes in nanoliter microfluidic cell culture volumes. | Release of neurotransmitters and hormones by calcium regulated exocytosis is a fundamental cellular/molecular process that is disrupted in a variety of psychiatric, neurological, and endocrine disorders. Therefore, this area represents a relevant target for drug and therapeutic development, efforts that will be aided b... | ['Aptamers, Nucleotide', 'Biosensing Techniques', 'Catecholamines', 'Chromaffin Cells', 'Electrochemical Techniques', 'Equipment Design', 'Exocytosis', 'Humans', 'Iridium', 'Luminescence', 'Microelectrodes', 'Microfluidics', 'Thrombin'] | 22,398,270 | [['D13.695.578.424.224'], ['E05.601.043'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['A06.224.161', 'A11.299'], ['E05.301'], ['E05.320'], ['G04.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.401', 'D01.268.956.280', 'D01.552.544.401'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Extrasynaptic receptors on cell bodies of neurons in central nervous system of the leech. | 1. A systematic study has been made of the sensitivity of identified sensory and motoneurons in the leech central nervous system to chemical transmitter substances. 2. The following substances elicited responses from the cell bodies of individual neurons: acetylcholine, 5-hydroxytryptamine, gamma-aminobutyric acid, glu... | ['Animals', 'Glutamates', 'Glycine', 'Leeches', 'Motor Neurons', 'Neurons', 'Neurons, Afferent', 'Neurotransmitter Agents', 'Receptors, Neurotransmitter', 'Stimulation, Chemical'] | 15,048 | [['B01.050'], ['D12.125.067.625', 'D12.125.119.409'], ['D12.125.481'], ['B01.050.500.091.426'], ['A08.675.655.500', 'A11.671.655.500'], ['A08.675', 'A11.671'], ['A08.675.650', 'A11.671.650'], ['D27.505.519.625', 'D27.505.696.577'], ['D12.776.543.750.720'], ['G07.690.773.996']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Solution structure of an extracellular domain containing the WSxWS motif of the granulocyte colony-stimulating factor receptor and its interaction with ligand. | We have determined the NMR structure of a ligand-binding domain of the granulocyte colony-stimulating factor (G-CSF) receptor, containing the highly conserved WSxWS motif. The domain consists of seven beta-strands with the fibronectin type III-like topology seen in several cytokine receptors. Comparisons between the sp... | ['Amino Acid Sequence', 'Animals', 'Binding Sites', 'Conserved Sequence', 'Evolution, Molecular', 'Granulocyte Colony-Stimulating Factor', 'Humans', 'Ligands', 'Magnetic Resonance Spectroscopy', 'Mice', 'Models, Molecular', 'Molecular Sequence Data', 'Protein Conformation', 'Receptors, Cytokine', 'Receptors, Granulocyt... | 9,187,659 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['G02.111.570.580'], ['G05.045.250', 'G16.075.250'], ['D12.644.276.374.410.240.350', 'D12.776.395.240.200', 'D12.776.467.374.410.240.350', 'D23.529.374.410.240.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.480'], ['E0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
In vivo potentiation of atracurium neuromuscular blockade by nimodipine in rabbits. | The interaction between nimodipine, a calcium channel blocker, used for the treatment of subarachnoid haemorrhage, and atracurium, was studied in rabbits. An intravenous dose of 0.1 mg.kg-1 of nimodipine given over 3 min caused a potentiation of the neuromuscular blocking action of atracurium (administered at an infusi... | ['Animals', 'Atracurium', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Drug Synergism', 'Muscle Contraction', 'Muscles', 'Neuromuscular Blocking Agents', 'Neuromuscular Junction', 'Nimodipine', 'Rabbits', 'Sciatic Nerve', 'Synaptic Transmission', 'Time Factors'] | 1,311,493 | [['B01.050'], ['D03.633.100.531.085.061'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['G07.690.773.968.477'], ['G11.427.494'], ['A02.633', 'A10.690'], ['D27.505.696.663.700.710'], ['A08.800.550.550.550', 'A08.850.550.550', 'A11.284.149.165.420.780.550.550'], ['D03.383.725.203.570', 'D03.383.725.547.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pre-existing renal failure worsens the outcome after intestinal ischaemia and reperfusion in rats. | BACKGROUND: Chronic kidney disease (CKD) serves as a risk factor in the development of acute kidney injury (AKI) requiring renal replacement therapy. Furthermore, superimposed AKI on CKD is associated with an increased mortality and risk of progression to end-stage renal disease. We aim to examine whether CKD increases... | ['Acute Kidney Injury', 'Acute-Phase Proteins', 'Animals', 'Blood Pressure', 'Chronic Disease', 'Disease Models, Animal', 'Heart Rate', 'Intestines', 'Ischemia', 'Kidney Diseases', 'Lipocalin-2', 'Lipocalins', 'Male', 'Multiple Organ Failure', 'Nephrectomy', 'Proto-Oncogene Proteins', 'Rats', 'Reperfusion Injury'] | 20,525,977 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['D12.776.124.050'], ['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C23.550.291.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.600.875.500', 'G09.330.380.500'], ['A03.556.124'], ['C23.550.513'], ['C12.777.419', 'C13.351.968.419'], ['D12.7... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mitochondria-targeted antioxidant promotes recovery of skeletal muscle mitochondrial function after burn trauma assessed by in vivo 31P nuclear magnetic resonance and electron paramagnetic resonance spectroscopy. | Burn injury causes a major systemic catabolic response that is associated with mitochondrial dysfunction in skeletal muscle. We investigated the effects of the mitochondria-targeted peptide antioxidant Szeto-Schiller 31 (SS-31) on skeletal muscle in a mouse burn model using in vivo phosphorus-31 nuclear magnetic resona... | ['Aconitate Hydratase', 'Adenosine Triphosphate', 'Animals', 'Antioxidants', 'Burns', 'Citric Acid Cycle', 'Electron Spin Resonance Spectroscopy', 'Magnetic Resonance Spectroscopy', 'Male', 'Mice', 'Mitochondria, Muscle', 'Muscle, Skeletal', 'Oligopeptides', 'Oxidation-Reduction', 'Oxidative Stress'] | 23,482,635 | [['D08.811.520.241.300.050'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C26.200'], ['G02.111.165', 'G03.295.342', 'G03.493.170'], ['E05.196.867.519.274'], ['E05.196.867.519'], ['B01.050.150.900.649.313.992... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Seasonal dynamics of nitrogen- and phosphorus absorption efficiency of wetland plants in Minjiang River estuary]. | Taking the native Phragmites australis and invasive Spartina alterniflora in Minjiang River estuary as test objectives, this paper studied the seasonal dynamics of their biomass and nitrogen- and phosphorus absorption efficiency. A typical single-peak curve was presented for the seasonal dynamics of aboveground biomass... | ['Absorption', 'China', 'Nitrogen', 'Phosphorus', 'Poaceae', 'Rivers', 'Seasons', 'Water Pollutants, Chemical', 'Wetlands'] | 19,795,639 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['Z01.252.474.164'], ['D01.268.604', 'D01.362.625'], ['D01.268.666'], ['B01.650.940.800.575.912.250.822'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['D27.888.284... | ['Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
First cleft branchial fistula in a child--a modified surgical technique. | Congenital first branchial cleft fistulae, their embryology, anomalies, varied relationships to the facial nerve and surgical techniques for their excision have been well described in the literature. We report a case of a type II first cleft fistula in a three-year-old child which required a modification of the standar... | ['Branchioma', 'Child, Preschool', 'Facial Nerve', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Neck'] | 7,861,086 | [['C04.182.117'], ['M01.060.406.448'], ['A08.800.050.050.275', 'A08.800.050.600.149', 'A08.800.800.060.275', 'A08.800.800.120.250'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.598']] | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bipyrimidine photoproducts rather than oxidative lesions are the main type of DNA damage involved in the genotoxic effect of solar UVA radiation. | Exposure to solar UV radiation gives rise to mutations that may lead to skin cancer. UVA (320-340 nm) constitutes the large majority of solar UV radiation but is less effective than UVB (290-320 nm) at damaging DNA. Although UVA has been implicated in photocarcinogenesis, its contribution to sunlight mutagenesis has no... | ['Animals', 'CHO Cells', 'Cricetinae', 'Cyclobutanes', 'DNA', 'DNA Damage', 'Isomerism', 'Mutagenesis', 'Oxidation-Reduction', 'Photons', 'Pyrimidine Dimers', 'Sunlight', 'Thymine', 'Ultraviolet Rays'] | 12,885,257 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250'], ['D02.455.426.392.368.201'], ['D13.444.308'], ['G05.200'], ['G02.111.570.685', 'G02.607.445'], ['G05.558'], ['G02.700', 'G03.295.531'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The molecular and electronic structure of the electron transfer series [Fe2(NO)2(S2C2R2)3](z) (z = 0, -1, -2; R = phenyl, p-tolyl, p-tert-butylphenyl). | Three dinuclear (nitrosyl)iron complexes containing three 1,2-di(phenyl)ethylene-1,2-dithiolate ligands have been prepared ([Fe2(NO)2(S2C2R2)3]0 (R = phenyl, 1a; p-tolyl, 2a; (4-tert-butyl)phenyl, 3a)). Each of these compounds represents the first member of a three-membered electron-transfer series: [Fe2(NO)2(S2C2R2)3]... | ['Crystallography, X-Ray', 'Electron Spin Resonance Spectroscopy', 'Electrons', 'Ferric Compounds', 'Ligands', 'Models, Molecular', 'Molecular Structure'] | 17,305,334 | [['E05.196.309.742.225'], ['E05.196.867.519.274'], ['G01.249.335', 'G01.358.500.750'], ['D01.490.100'], ['D27.720.470.480'], ['E05.599.595'], ['G02.111.570', 'G02.466']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of CPP-ACP and Nd:YAG laser on the bond strength of softened dentin. | The purpose of this study was to investigate the effect of CPP-ACP treatment and Nd:YAG laser on microtensile bond strength (µTBS) of softened dentin. Sixty samples were obtained from thirty sound third molars. All samples were submitted to dentin softening procedure, by the immersion of the specimens in 30 mL of Sprit... | ['Analysis of Variance', 'Caseins', 'Chelating Agents', 'Composite Resins', 'Dental Bonding', 'Dental Restoration Failure', 'Dentin', 'Dentin-Bonding Agents', 'Humans', 'Immersion', 'Lasers, Solid-State', 'Materials Testing', 'Random Allocation', 'Reproducibility of Results', 'Resin Cements', 'Statistics, Nonparametric... | 26,083,086 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.095'], ['E06.323.400', 'E06.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
HIV risk behaviors and sociodemographic features of HIV-infected Latinos residing in a new Latino settlement area in the Southeastern United States. | The Southeastern United States (US) has a rapidly growing Latino population, yet little is known about HIV-infected Latinos in the region. To help inform future prevention studies, we compared sociodemographic, clinical, and behavioral characteristics between immigrant and US-born HIV-infected Latinos using face-to-fac... | ['Adult', 'CD4 Lymphocyte Count', 'Emigrants and Immigrants', 'Female', 'HIV Infections', 'Hispanic Americans', 'Humans', 'Male', 'Middle Aged', 'North Carolina', 'Poverty', 'Risk Factors', 'Risk-Taking', 'Southeastern United States', 'Surveys and Questionnaires', 'Unsafe Sex'] | 23,384,328 | [['M01.060.116'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500.150', 'G04.140.107.595.500.150', 'G09.188.105.595.500.150'], ['M01.189'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Development of knowledge tests for multi-disciplinary emergency training: a review and an example. | BACKGROUND: The literature is sparse on written test development in a post-graduate multi-disciplinary setting. Developing and evaluating knowledge tests for use in multi-disciplinary post-graduate training is challenging. The objective of this study was to describe the process of developing and evaluating a multiple-c... | ['Anesthesiology', 'Clinical Competence', 'Educational Measurement', 'Emergencies', 'Humans', 'Obstetrics'] | 25,363,488 | [['H02.403.066'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.399'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.450']] | ['Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
The 'present state' examination and the structured clinical interview in Zulu. | The language, cultural and reality factors found to be important in the Zulu translation of the 'present state' examination (PSE) and the structured clinical interview for the Diagnostic and Statistical Manual of Mental Disorders (SCID) are discussed and compared with a previous translation of the PSE in Xhosa. The psy... | ['African Americans', 'African Continental Ancestry Group', 'Cultural Characteristics', 'Humans', 'Interview, Psychological', 'Language', 'Psychopathology', 'South Africa', 'Surveys and Questionnaires'] | 1,989,098 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.686.508.100'], ['I01.076.201.450.324', 'I01.880.853.100.329'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.669.599'], ['F01.145.209.399', 'L01.559'], ['F04.096.670'], ['Z01.058.290.175.735'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Coronary artery aneurysms in Wegener's granulomatosis. | Atherosclerosis is the main cause of coronary artery aneurysm, however they can be observed in connective tissue diseases such as systemic lupus erythematosus and vasculitis. Kawasaki's disease and polyarteritis nodosa (PAN) are the systemic vasculitis that more often present coronary artery aneurysms. There are descri... | ['Adult', 'Antibodies, Antineutrophil Cytoplasmic', 'Coronary Aneurysm', 'Coronary Angiography', 'Cyclophosphamide', 'Glucocorticoids', 'Granulomatosis with Polyangiitis', 'Humans', 'Male', 'Methylprednisolone', 'Myeloblastin', 'Myocardial Infarction', 'Treatment Outcome'] | 21,195,005 | [['M01.060.116'], ['D12.776.124.486.485.114.323.190', 'D12.776.124.790.651.114.323.190', 'D12.776.377.715.548.114.323.190', 'D23.101.050'], ['C14.280.647.250.250', 'C14.907.055.395', 'C14.907.585.250.250'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['D02.455.526.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Study on prolonged action cefotoxime]. | A prolonged action cephalosporin was prepared by the reaction of cefotaxime sodium (CTX) with N,N-dibenzylethylene diamine acetate. It is reasonable to consider the resultant as benzathine cefotaxime (BCTX) by means of elemental analysis, DSC, UV spectra, IR spectra, NMR spectra and mass spectra. In contrast to CTX, BC... | ['Animals', 'Cefotaxime', 'Delayed-Action Preparations', 'Rabbits'] | 2,239,322 | [['B01.050'], ['D02.065.589.099.249.190.190', 'D02.886.665.074.190.190', 'D03.633.100.300.249.190.190'], ['D26.255.210', 'E02.319.300.253'], ['B01.050.150.900.649.313.968.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Ultrasound diagnosis of the locomotor system]. | Improvements of ultrasound technology with knew equipments allowed enormous advances in all fields of medicine during the last years. Several conditions concerning technical equipment and training of the operator have to be fulfilled to guarantee sufficient quality of the diagnostic information obtained in musculoskele... | ['Contrast Media', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Joint Diseases', 'Magnetic Resonance Imaging', 'Musculoskeletal Diseases', 'Sensitivity and Specificity', 'Ultrasonography', 'Ultrasonography, Doppler', 'Ultrasonography, Interventional'] | 12,428,436 | [['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.400', 'L01.224.308.410'], ['C05.550'], ['E01.370.350.825.500'], ['C05'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.52... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Age polyethism drives community structure of the bacterial gut microbiota in the fungus-cultivating termite Odontotermes formosanus. | Fungus-cultivating termites (Macrotermitinae) possess an elaborate strategy of lignocellulose digestion. It involves a lignocellulose-degrading fungal symbiont (genus Termitomyces), a diverse gut microbiota and a characteristic labour division in food processing. In this study, using pyrotag sequencing and electron mic... | ['Aging', 'Animals', 'Bacteria', 'Digestive System', 'Fungi', 'Gastrointestinal Microbiome', 'Isoptera'] | 26,346,907 | [['G07.345.124'], ['B01.050'], ['B03'], ['A03'], ['B01.300'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['B01.050.500.131.617.485']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Sodium bicarbonate abuse: a case report. | Sodium bicarbonate abuse is unusual, and rarely reported. A patient was extensively investigated at several hospitals for a recurrent hypokalaemic metabolic alkalosis; it transpired that she had been abusing sodium bicarbonate for 8 years and had gained hospital admission at will by taking large amounts. She also showe... | ['Adult', 'Alkalosis', 'Bicarbonates', 'Female', 'Humans', 'Hypokalemia', 'Munchausen Syndrome', 'Sodium', 'Sodium Bicarbonate', 'Substance-Related Disorders'] | 3,028,562 | [['M01.060.116'], ['C18.452.076.354'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.950.565'], ['F03.875.375.600'], ['D01.268.549.750', 'D01.268.557.650', 'D01.552.528.850', 'D01.552.547.725'], ['D01.200.275.150.100.800', 'D01.857.625'], ['C25.775', 'F03... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Synthesis, antifungal and antimicrobial activity of alkylphospholipids. | The antifungal, antibacterial and haemolytic activity of a series of alkylphosphocholines (e.g., miltefosine) and alkylglycerophosphocholines (e.g., edelfosine) has been investigated. These compound classes exhibit significant antifungal and moderate antibacterial activities. Several new alkylphosphocholine derivatives... | ['Anti-Bacterial Agents', 'Antifungal Agents', 'Bacteria', 'Erythrocytes', 'Fungi', 'Molecular Structure', 'Phospholipids', 'Structure-Activity Relationship'] | 17,532,639 | [['D27.505.954.122.085'], ['D27.505.954.122.136'], ['B03'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.300'], ['G02.111.570', 'G02.466'], ['D10.570.755'], ['G02.111.830', 'G07.690.773.997']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cyclooxygenase selectivity of nonsteroidal anti-inflammatory drugs in canine blood. | OBJECTIVE: To evaluate cyclooxygenase (COX) selectivity of several nonsteroidal anti-inflammatory drugs (NSAID) in canine blood in vitro.ANIMALS: 11 healthy adult male hound crosses.PROCEDURE: 9 NSAID were studied at 5 concentrations. Thromboxane B2 (TxB2) was assayed as a measure of COX-1 activity in clotted blood. Pr... | ['Animals', 'Cross-Over Studies', 'Cyclooxygenase 1', 'Cyclooxygenase 2', 'Cyclooxygenase 2 Inhibitors', 'Cyclooxygenase Inhibitors', 'Dinoprostone', 'Dogs', 'Dose-Response Relationship, Drug', 'Gene Expression Regulation, Enzymologic', 'Male', 'Prostaglandin-Endoperoxide Synthases', 'Thromboxane B2'] | 16,206,787 | [['B01.050'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D08.811.600.720.500'], ['D08.811.600.720.750'], ['D27.505.519.389.310.500', 'D27.505.696.663.850.014.040.500.500.500', 'D27.505.954.158.030.500.500', 'D27.505.954.329.030.500.500'], ['D27.505.519.389.310', 'D27.505.696.663.850.014.040.50... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
VEGF and VEGFR1 levels in different regions of the normal and preeclampsia placentae. | Altered placental angiogenesis is implicated in the pathophysiology of preeclampsia. We have earlier reported placental regional differences in oxidative stress markers and neurotrophins. Oxidative stress and neurotrophins are reported to regulate angiogenesis. This study aims to examine protein and mRNA levels of vasc... | ['Adolescent', 'Adult', 'Cross-Sectional Studies', 'Female', 'Humans', 'Placenta', 'Pre-Eclampsia', 'Pregnancy', 'Vascular Endothelial Growth Factor A', 'Vascular Endothelial Growth Factor Receptor-2'] | 28,770,473 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A16.710'], ['C13.703.395.249'], ['G08.686.784.769'], ['D12.644.276.100.800.200', 'D12.776.467.100.800.200', 'D23.529.100.800.200'], ['D08.811.913.696.620.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
LORETA indicates frequency-specific suppressions of current sources within the cerebrums of blindfolded subjects from patterns of blue light flashes applied over the skull. | An array of eight cloistered (completely covered) 470-nm LEDs was attached to the right caudal scalp of subjects while each sat blindfolded within a darkened chamber. The LEDs were activated by a computer-generated complex (frequency-modulated) temporal pattern that, when applied as weak magnetic fields, has elicited s... | ['Adult', 'Alpha Rhythm', 'Analysis of Variance', 'Beta Rhythm', 'Electromagnetic Fields', 'Gamma Rhythm', 'Hippocampus', 'Humans', 'Male', 'Photic Stimulation', 'Skull', 'Temporal Lobe', 'Tomography, X-Ray Computed'] | 26,276,250 | [['M01.060.116'], ['E01.370.376.300.150.374', 'E01.370.405.245.287.374', 'G07.265.087.500', 'G11.561.127.500'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.376.300.150.750', 'E01.370.405.245.287.750', 'G07.265.087.750', 'G11.561.127.750'], ['G01.358.500.260', 'G01.358.750.500'], ['E01.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ethanol alters cellular activation and CD14 partitioning in lipid rafts. | Alcohol consumption interferes with innate immunity. In vivo EtOH administration suppresses cytokine responses induced through Toll-like receptor 4 (TLR4) and inhibits TLR4 signaling. Actually, EtOH exhibits a generalized suppressive effect on signaling and cytokine responses induced by through most TLRs. However, the ... | ['Animals', 'Cell Line', 'Dose-Response Relationship, Drug', 'Ethanol', 'Lipopolysaccharide Receptors', 'Lipopolysaccharides', 'Macrophages', 'Membrane Microdomains', 'Mice', 'Receptors, Immunologic', 'Signal Transduction', 'Toll-Like Receptor 4', 'Tumor Necrosis Factor-alpha', 'beta-Cyclodextrins'] | 15,896,296 | [['B01.050'], ['A11.251.210'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.033.375'], ['D12.776.395.550.448.100', 'D12.776.543.484.500.100', 'D12.776.543.550.418.100', 'D12.776.543.750.705.045', 'D23.050.301.264.900.045', 'D23.101.100.900.045'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D2... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genistein inhibits cell growth by modulating various mitogen-activated protein kinases and AKT in cervical cancer cells. | Genistein, a soy-derived isoflavone, inhibits growth of tumor cells from various malignancies. Here we investigated the effect of genistein on the growth of cervical cancer cells (HeLa and CaSki) and its possible mechanism. Genistein significantly suppressed cell growth of HeLa and CaSki cells at concentrations of 20 a... | ['Androstadienes', 'Anthracenes', 'Anticarcinogenic Agents', 'Blotting, Western', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Dose-Response Relationship, Drug', 'Enzyme Inhibitors', 'Female', 'Flavonoids', 'Genistein', 'HeLa Cells', 'Humans', 'Imidazoles', 'JNK Mitogen-Activated Protein Kinases', 'Mitog... | 19,723,095 | [['D04.210.500.054.079.129'], ['D02.455.426.559.847.117', 'D04.615.117'], ['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750']... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sacrococcygeal pilonidal disease. | BACKGROUND: Sacrococcygeal pilonidal is a common disease in active young adults. Many surgical methods have been proposed, although no clear consensus as to the optimal treatment has been reported. This review looks at the different surgical techniques available and examines the reported results of primary healing, rec... | ['Adolescent', 'Ambulatory Surgical Procedures', 'Humans', 'Meta-Analysis as Topic', 'Pilonidal Sinus', 'Randomized Controlled Trials as Topic', 'Surgical Flaps', 'Suture Techniques', 'Wound Healing', 'Young Adult'] | 18,384,421 | [['M01.060.057'], ['E04.030'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.500', 'E05.581.500.501', 'N05.715.360.325.515', 'N06.850.520.445.500'], ['C04.182.710'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500'], ['A10.850.710', 'E07.862.710'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Histopathological features predictive of a clinical diagnosis of ophthalmic granulomatosis with polyangiitis (GPA). | BACKGROUND: The limited form of Granulomatosis with Polyangiitis (GPA), formerly known as Wegener's Granulomatosis (WG) primarily involves the head and neck region, including the orbit, but is often a diagnostic challenge, particularly as it commonly lacks positive anti-neutrophil cytoplasm antibody (ANCA) titres or cl... | ['Antibodies, Antineutrophil Cytoplasmic', 'Eosinophils', 'Female', 'Granulomatosis with Polyangiitis', 'Humans', 'Male', 'Middle Aged', 'Necrosis', 'Neutrophil Infiltration', 'Neutrophils', 'Orbital Diseases', 'Retrospective Studies', 'Vasculitis'] | 22,977,665 | [['D12.776.124.486.485.114.323.190', 'D12.776.124.790.651.114.323.190', 'D12.776.377.715.548.114.323.190', 'D23.101.050'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['C08.381.483.950', 'C14.907.940.897.249.750', 'C20.111.193.875'], ['B01.050.150.900.649.313.988.400.11... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sequential Integration of Fuzzy Clustering and Expectation Maximization for Transcription Factor Binding Site Identification. | The identification of transcription factor binding sites (TFBSs) is a problem for which computational methods offer great hope. Thus far, the expectation maximization (EM) technique has been successfully utilized in finding TFBSs in DNA sequences, but inappropriate initialization of EM has yielded poor performance or r... | ['Algorithms', 'Binding Sites', 'Chromatin Immunoprecipitation', 'Cluster Analysis', 'Computational Biology', 'Fuzzy Logic', 'Humans', 'Nucleotide Motifs', 'Protein Binding', 'Sequence Analysis, DNA', 'Transcription Factors'] | 30,133,315 | [['G17.035', 'L01.224.050'], ['G02.111.570.120'], ['E05.393.170', 'E05.478.605.160'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['H01.158.273.180', 'L01.313.124'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.080.611',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Humanities [K]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Ghrelin inhibits insulin secretion through the AMPK-UCP2 pathway in beta cells. | Ghrelin inhibits insulin secretion partly via induction of IA-2beta. However, the orexigenic effect of ghrelin is mediated by the AMP-activated protein kinase (AMPK)-uncoupling protein 2 (UCP2) pathway. Here, we demonstrate that ghrelin's inhibitory effect on insulin secretion also occurs through the AMPK-UCP2 pathway.... | ['AMP-Activated Protein Kinases', 'Animals', 'Cell Line', 'Enzyme Activation', 'Ghrelin', 'Glucose', 'Insulin', 'Insulin Secretion', 'Insulin-Secreting Cells', 'Ion Channels', 'Mice', 'Mitochondrial Proteins', 'Receptor-Like Protein Tyrosine Phosphatases, Class 8', 'Signal Transduction', 'Uncoupling Protein 2', 'Up-Reg... | 20,206,170 | [['D08.811.913.696.620.682.700.085', 'D12.644.360.062', 'D12.776.476.062'], ['B01.050'], ['A11.251.210'], ['G02.111.263', 'G03.328'], ['D06.472.699.301', 'D12.644.548.322'], ['D09.947.875.359.448'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['A03.734.414.131', 'A06.300.414.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coexistent sarcoidosis and HIV infection: an immunological paradox? | The CD4 lymphocyte plays a pivotal role in both sarcoidosis and HIV infection. Caring for a patient with both conditions represents a diagnostic and therapeutic challenge. We describe a patient, previously diagnosed with sarcoidosis, who subsequently contracted HIV infection. Manifestations of sarcoidosis were clinical... | ['Adult', 'Anti-HIV Agents', 'Antiretroviral Therapy, Highly Active', 'Female', 'HIV Infections', 'Humans', 'Prednisone', 'Sarcoidosis'] | 16,083,964 | [['M01.060.116'], ['D27.505.954.122.388.077.088'], ['E02.319.310.075'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.432.719.702'], ['C15.604.515.827']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of nurse staffing on hospital-acquired conditions and length of stay in community hospitals. | BACKGROUND: Error-free care is the goal of health care professionals, consumers, and public policy makers. Because nurses can be the last barrier between a patient and an error, there is a need to examine this pressing nursing issue-nurse staffing.PURPOSE: This research examined the predictive relationships between nur... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Cross Infection', 'Cross-Sectional Studies', 'Databases as Topic', 'Hospitals, Community', 'Humans', 'Infant', 'Infant, Newborn', 'Length of Stay', 'Middle Aged', "Nurse's Role", 'Nursing Staff, Hospital', 'Public Policy', 'Young Adult'] | 20,351,541 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['C01.248', 'C23.550.291.875.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['L01.313.500.750.300.188', 'L01.470.750'], ['N02.278.421.306'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Extra-oral fistula caused by a dental implant. | Dental implantation has become an important procedure for both dental treatment and head and neck reconstructive surgery. However, this useful technique sometimes results in peri-implantitis. We describe a rare complication of peri-implantitis in the maxilla which extended to the soft tissue and caused an extra-oral fi... | ['Aged', 'Cutaneous Fistula', 'Dental Fistula', 'Dental Implants', 'Female', 'Humans', 'Maxillary Diseases', 'Osteolysis', 'Peri-Implantitis'] | 20,545,551 | [['M01.060.116.100'], ['C17.800.135', 'C23.300.575.150'], ['C07.465.614.187', 'C23.300.575.500.275'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.500.693', 'C07.320.660'], ['C05.116.264.579', 'G11.427.213.150.570'], ['C07.465.714.282']... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Multiple activation of chloroform in hepatic microsomes from uninduced B6C3F1 mice. | The covalent binding of 14C-label to proteins and lipids was measured after incubation of hepatic microsomes from B6C3F1 mice with different concentrations of [14C]chloroform and oxygen. The effect of reduced glutathione on the covalent binding curves was also investigated. The results indicated that chloroform is acti... | ['Animals', 'Chloroform', 'Cytochrome P-450 Enzyme System', 'Dose-Response Relationship, Drug', 'Glutathione', 'Lipid Metabolism', 'Mice', 'Mice, Inbred Strains', 'Microsomes, Liver', 'Oxygen', 'Proteins'] | 2,385,839 | [['B01.050'], ['D02.455.526.439.224', 'D02.455.526.913.810'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.644.456.448'], ['G03.458'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The putative rat choline transporter CHOT1 transports creatine and is highly expressed in neural and muscle-rich tissues. | A rabbit homolog of the putative rat choline transporter CHOT1 has recently been shown to mediate creatine transport (Guimbal and Kilimann, J. Biol. Chem., 1993). Here, the functional properties of the CHOT1 cDNA were studied by heterologous expression in HEK-293 cells. After transfection, the cells displayed a 7-8fold... | ['Animals', 'Base Sequence', 'Biological Transport', 'Blotting, Northern', 'Brain', 'Brain Chemistry', 'Carrier Proteins', 'Cell Line', 'Creatinine', 'DNA, Complementary', 'Guanidines', 'Humans', 'In Situ Hybridization', 'Molecular Sequence Data', 'Muscles', 'Nerve Tissue Proteins', 'Plasma Membrane Neurotransmitter Tr... | 8,297,374 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G03.143'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['A08.186.211'], ['G02.111.150', 'G03.185'], ['D12.776.157'], ['A11.251.210'], ['D03.383.129.308.207'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Spectroscopic Properties of Amine-substituted Analogues of Firefly Luciferin and Oxyluciferin. | Spectroscopic and photophysical properties of firefly luciferin and oxyluciferin analogues with an amine substituent (NH2 , NHMe and NMe2 ) at the C6' position were studied based on absorption and fluorescence measurements. Their ð-electronic properties were investigated by DFT and TD-DFT calculations. These compounds ... | ['Amines', 'Firefly Luciferin', 'Indoles', 'Luciferases, Firefly', 'Luminescence', 'Proton Magnetic Resonance Spectroscopy', 'Pyrazines', 'Solvents', 'Spectrometry, Fluorescence', 'Spectrometry, Mass, Electrospray Ionization', 'Spectrophotometry, Ultraviolet'] | 27,796,043 | [['D02.092'], ['D02.886.675.298', 'D03.383.129.708.298'], ['D03.633.100.473'], ['D08.811.682.517.750', 'D12.776.093.500.577', 'D12.776.532.510.500'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.750.250.650.665', 'G01.750.770.578.665'], ['E05.196.867.519.775'], ['D03.383.679'], ['D27.720.844'], ['E05.196.712.516... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Noncurative Resection for Gastric Cancer Patients: Who Could Benefit? : Determining Prognostic Factors for Patient Selection. | BACKGROUND: Resections have long been recommended for patients with incurable gastric cancer. However, high morbidity rates and more efficient chemotherapy regimens have demanded more accurate patient selection. The aim of this study was to analyze the results of gastric cancer patients treated with noncurative resecti... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Follow-Up Studies', 'Gastrectomy', 'Humans', 'Lymph Node Excision', 'Male', 'Middle Aged', 'Morbidity', 'Neoplasm Staging', 'Neoplasm, Residual', 'Patient Selection', 'Prognosis', 'Retrospective Studies', 'Stomach Neoplasms', 'Survival Rate', 'Time Fac... | 26,542,593 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.446'], ['M01.060.116.630'], ['E05.318.308.985.525', 'N01.224.935.597... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of vitamin B-6 deficiency on preference for several taste solutions in the rat. | The effect of dietary-induced vitamin B-6 (B-6) deficiency on the intake of the taste solutions, sodium chloride (NaCl), sodium saccharin (NaSacc), quinine sulfate (QS), and hydrochloric acid (HCl) was studied using a 48 hour, two-bottle choice technique. The B-6 deficient group demonstrated increased preference to 1.5... | ['Adrenal Glands', 'Hydrochloric Acid', 'Hypertrophy', 'Pyridoxine', 'Quinine', 'Saccharin', 'Sodium', 'Sodium Chloride', 'Taste', 'Vitamin B 6 Deficiency', 'Zinc'] | 430,235 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Towards understanding the mechanism of action of antibacterial N-alkyl-3-hydroxypyridinium salts: Biological activities, molecular modeling and QSAR studies. | In this study, we have carried out a combined experimental and computational investigation to elucidate several bred-in-the-bone ideas standing out in rational design of novel cationic surfactants as antibacterial agents. Five 3-hydroxypyridinium salts differing in the length of N-alkyl side chain have been synthesized... | ['Animals', 'Anti-Bacterial Agents', 'Bacteria', 'CHO Cells', 'Cell Survival', 'Cricetinae', 'Cricetulus', 'Fungi', 'Hydrophobic and Hydrophilic Interactions', 'Molecular Conformation', 'Molecular Dynamics Simulation', 'Pyridines', 'Quantitative Structure-Activity Relationship'] | 27,341,309 | [['B01.050'], ['D27.505.954.122.085'], ['B03'], ['A11.251.210.200', 'A11.436.155'], ['G04.346'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['B01.300'], ['G02.409'], ['G02.111.570.820'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D03.383.725'], ['G02.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Early diagnosis of herpes simplex virus encephalitis by single photon emission computed tomography (SPECT) in patients with normal MRI]. | Since treatment of herpes simplex virus encephalitis (HSVE) is most effective when started early, a sensitive and specific method for early diagnosis would be of great benefit. MRI and CT are commonly used for this purpose. In this study, we presented two patients who had serologically confirmed HSVE and had normal CT ... | ['Encephalitis, Viral', 'Herpes Simplex', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Tomography, Emission-Computed, Single-Photon'] | 8,741,353 | [['C01.207.245.340', 'C01.207.399.750', 'C01.925.182.525', 'C10.228.140.430.520.750', 'C10.228.228.245.340', 'C10.228.228.399.750'], ['C01.925.256.466.382', 'C01.925.825.320', 'C17.800.838.790.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E01.370.350.350.800.800... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Visual servoing for intraoperative positioning and repositioning of mobile C-arms. | The problem of positioning mobile C-arms, e.g. for down the beam techniques, as well as repositioning during surgical procedures currently requires time, skill and additional radiation. This paper uses a Camera-Augmented Mobile C-arm (CAMC) to speed up the procedure, simplify its execution and reduce the necessary radi... | ['Algorithms', 'Ankle', 'Artificial Intelligence', 'Humans', 'Imaging, Three-Dimensional', 'Motion', 'Pattern Recognition, Automated', 'Radiographic Image Enhancement', 'Radiographic Image Interpretation, Computer-Assisted', 'Reproducibility of Results', 'Robotics', 'Sensitivity and Specificity', 'Tomography, X-Ray Com... | 17,354,934 | [['G17.035', 'L01.224.050'], ['A01.378.610.050'], ['G17.035.250', 'L01.224.050.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['G01.482'], ['L01.399.750'], ['E01.370.350.600.350.700', 'E01.370.350.700.700', 'L01.224.308.380.600'], ['E01.158.600.680', 'E01.370.350.350.700... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Double-level "orthogonal" dynamic combinatorial libraries on transition metal template. | Dynamic combinatorial libraries are mixtures of compounds that exist in a dynamic equilibrium and can be driven to compositional self adaptation via selective binding of a specific assembly of certain components to a molecular target. We present here an extension of this initial concept to dynamic libraries that consis... | ['Aldehydes', 'Cobalt', 'Ethers', 'Hydrazones', 'Imines', 'Ligands', 'Molecular Structure', 'Pyridines'] | 11,171,953 | [['D02.047'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['D02.355'], ['D02.442.288'], ['D02.491'], ['D27.720.470.480'], ['G02.111.570', 'G02.466'], ['D03.383.725']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Traffic-related air pollution is related to interrupter resistance in 4-year-old children. | Outdoor air pollution has been associated with decrements in lung function and growth of lung function in school-age children. Lung function effects have not been examined in preschoolers, with the exception of one study on minute ventilation in newborns. Our goal was to assess the relationship between long- and short-... | ['Air Pollutants', 'Air Pollution', 'Asthma', 'Child, Preschool', 'Cohort Studies', 'Environmental Exposure', 'Environmental Monitoring', 'Female', 'Humans', 'Male', 'Nitrogen Dioxide', 'Particulate Matter', 'Regression Analysis', 'Respiratory Function Tests', 'Respiratory Sounds', 'Sensitivity and Specificity', 'Soot'... | 23,143,551 | [['D27.888.284.101'], ['N06.850.460.100'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N06.850.460.350'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.649.313.988.400.112.... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chronic Statin Use and Long-Term Rates of Sepsis: A Population-Based Cohort Study. | PURPOSE: "Statins" have immunomodulatory and anti-inflammatory effects and may attenuate the risk of infections. We sought to determine the association between chronic statin use and long-term rates of sepsis events.MATERIALS AND METHODS: We used data from 30 183 adult (?45 years old) community-dwelling participants in... | ['Aged', 'C-Reactive Protein', 'Cohort Studies', 'Female', 'Hospitalization', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Male', 'Middle Aged', 'Proportional Hazards Models', 'Risk Factors', 'Sepsis', 'United States'] | 25,223,827 | [['M01.060.116.100'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.505.954... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Electron microscopic studies of plasmic degradation products of fibrinogen. Implications for the disulfide structure of fibrinogen. | Fibrinogen, coagulable plasmic derivatives (Fragments X) and Fragments Y, D and E were studied by negative staining electron microscopy. Fragment X obtained from Stage 1 digests and fibrinogen were both globular, while Fragment X of Stage 2 digests appeared as a nodular filament. The Stage 1 and Stage 2 Fragment X prep... | ['Binding Sites', 'Blood Coagulation Tests', 'Disulfides', 'Fibrinogen', 'Fibrinolysin', 'Humans', 'Microscopy, Electron', 'Peptide Fragments', 'Protein Binding', 'Protein Conformation'] | 126,081 | [['G02.111.570.120'], ['E01.370.225.625.115', 'E05.200.625.115'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['D08.811.277.656.300.760.330', 'D08.811.277.656.959.350.330'], ['B01.050.150.900.649.313.988.400.112... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
'Slowing down when you should': initiators and influences of the transition from the routine to the effortful. | BACKGROUND: 'Slowing down when you should' has been described as marking the transition from 'automatic' to 'effortful' functioning in professional practice. The ability to 'slow down' is hypothesized as an important factor in expert judgment. This study explored the nature of the 'slowing down' phenomenon intraoperati... | ['Attitude of Health Personnel', 'Clinical Competence', 'Hospitals, University', 'Humans', 'Judgment', 'Medical Errors', 'Problem Solving', 'Surgical Procedures, Operative', 'Urban Population'] | 20,309,647 | [['F01.100.050', 'N05.300.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.785.626'], ['N02.421.450'], ['F02.463.425.725', 'F02.463.785.810'], ['E04'], ['N01.600.900']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Primary diffuse leptomeningeal gliomatosis. | BACKGROUND: Primary diffuse leptomeningeal gliomatosis (PDLG) is a rare presentation of a primary central nervous system glial tumor.METHODS: Four case reports of PDLG in young males aged 14-24 years are presented. These reports are discussed in the context of the existing literature.RESULTS: The clinical presentation ... | ['Adolescent', 'Antineoplastic Agents, Alkylating', 'Brain', 'Dacarbazine', 'Diagnosis, Differential', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Meningeal Neoplasms', 'Meninges', 'Meningitis', 'Neoplasms, Neuroepithelial', 'Perfusion Imaging', 'Spinal Cord', 'Temozolomide', 'Treatment Outcome', 'Young Adult'] | 19,407,451 | [['M01.060.057'], ['D27.505.519.124.035', 'D27.505.954.248.150', 'D27.888.569.035.035'], ['A08.186.211'], ['D02.925.200', 'D03.383.129.308.240'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C04.588.614.250.580', 'C10.551.240.500'], ['A08.186.566'], ['C10.228.614'], ['C04.557... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enhancement of transcriptional activity of the Escherichia coli trp promoter by upstream A + T-rich regions. | The Escherichia coli trp promoter has two A + T-rich blocks in the upstream region. The deletion of the segments containing these blocks resulted in a decrease in promoter strength. By replacing the upstream region of trp promoter with one or two large A + T-rich blocks of the major leftward lambda promoter (pL), modif... | ['Adenine', 'Base Composition', 'Base Sequence', 'Enhancer Elements, Genetic', 'Escherichia coli', 'Genes, Regulator', 'Plasmids', 'Promoter Regions, Genetic', 'Thymine', 'Transcription, Genetic', 'Tryptophan'] | 3,533,725 | [['D03.633.100.759.138'], ['G02.111.080'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.080.689.330', 'G05.360.080.689.330', 'G05.360.340.024.340.137.750.249'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.425'], ['G05.360.600'], ['G02.111.570.080.689.675', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A comparison of three formulations of TAC (tetracaine, adrenalin, cocaine) for anesthesia of minor lacerations in children. | A randomized, prospective, double-blind study comparing three formulations of the topical anesthetic solution TAC for laceration repair was undertaken in 250 children. The children's wounds were anesthetized with either TAC I (original formulation--0.5% tetracaine, 1:2000 Adrenalin, 11.8% cocaine), TAC II (1.0% tetraca... | ['Adolescent', 'Analysis of Variance', 'Anesthetics, Local', 'Child', 'Child, Preschool', 'Cocaine', 'Double-Blind Method', 'Drug Combinations', 'Drug Evaluation', 'Epinephrine', 'Female', 'Humans', 'Infant', 'Male', 'Postoperative Complications', 'Prospective Studies', 'Skin', 'Tetracaine'] | 2,290,723 | [['M01.060.057'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['M01.060.406'], ['M01.060.406.448'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['E05.318.370.300', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation. | Transforming growth factor-beta (TGF-beta) plays a central role in the pathogenesis of inflammatory and fibrotic diseases, including radiation-induced fibrosis. We previously reported that mice null for Smad3, a key downstream mediator of TGF-beta, show accelerated healing of cutaneous incisional wounds with reduced in... | ['Animals', 'Cell Survival', 'DNA-Binding Proteins', 'Fibroblasts', 'Gamma Rays', 'Keratinocytes', 'Mice', 'Mice, Knockout', 'Radiation Injuries, Experimental', 'Skin', 'Smad3 Protein', 'Trans-Activators', 'Transforming Growth Factor beta'] | 11,891,202 | [['B01.050'], ['G04.346'], ['D12.776.260'], ['A11.329.228'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['A11.409.500', 'A11.436.397'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.313.992.635.505.500... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Moderate to severe periodic limb movement disorder in childhood and adolescence. | The purpose of this study is to review clinical features of children with moderate to severe Periodic Limb Movement Disorder (PLMD). Because of our interest in both Restless Legs Syndrome (RLS) and Attention-Deficit Hyperactivity Disorder (ADHD), many of our patients had one or both of these conditions. We did a retros... | ['Adolescent', 'Child', 'Female', 'Humans', 'Male', 'Movement Disorders', 'Polysomnography', 'Psychiatric Status Rating Scales', 'Retrospective Studies', 'Sleep'] | 10,341,379 | [['M01.060.057'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.662'], ['E01.370.520.625'], ['F04.711.513.653'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transcriptome changes in age-related macular degeneration. | Age-related macular degeneration (AMD) is a debilitating, common cause of visual impairment. While the last decade has seen great progress in understanding the pathophysiology of AMD, the molecular changes that occur in eyes with AMD are still poorly understood. In the current issue of Genome Medicine, Newman and colle... | ['Eye', 'Gene Expression Profiling', 'Humans', 'Macular Degeneration', 'Protein Interaction Maps', 'Transcriptome'] | 22,369,667 | [['A01.456.505.420', 'A09.371'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.768.585.439'], ['G03.493.750'], ['G02.111.873.750', 'G05.297.700.750', 'G05.360.920']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Residues affecting hydrolysis of soy isoflavone glycosides, stability and catalytic properties of Thermotoga maritime â-glucosidase]. | The thermostable â-glucosidase A (TmBglA) from Thermotoga maritime is a promising biocatalyst for production of isoflavone aglycones. Use of enzymes with high specificity for soy isoflavone conjugates is however essential for efficient hydrolysis. The effect of the amino acids located in the aglycone binding pocket wit... | ['Amino Acid Substitution', 'Bacterial Proteins', 'Benzyl Alcohols', 'Catalysis', 'Enzyme Stability', 'Glucosides', 'Isoflavones', 'Mutation, Missense', 'Recombinant Proteins', 'Soybeans', 'Thermotoga maritima', 'beta-Glucosidase'] | 25,474,868 | [['E05.393.420.601.035', 'G05.558.109'], ['D12.776.097'], ['D02.033.160', 'D02.455.426.559.389.140.200'], ['G02.130'], ['E05.916.360', 'G02.111.700.500'], ['D09.408.348'], ['D03.383.663.283.266.450.400', 'D03.633.100.150.266.450.400'], ['G05.365.590.650'], ['D12.776.828'], ['B01.650.940.800.575.912.250.401.750'], ['B03... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Volume, nature and potential impact of advertisements on Facebook and YouTube by food brands popular in New Zealand. | AIM: To analyse extent, nature and potential impact of marketing by food and beverage brands popular in New Zealand on Facebook and YouTube.METHOD: Popular food and beverage brands in New Zealand were selected from Socialbakers. Posts on Facebook pages of 45 packaged food, beverage and fast food companies over two mont... | ['Advertising', 'Food', 'Humans', 'New Zealand', 'Social Media'] | 29,649,193 | [['J01.219.687.274', 'L01.143.050'], ['G07.203.300', 'J02.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.639.760.747', 'Z01.678.100.747'], ['L01.178.751', 'L01.224.230.110.500.750']] | ['Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 |
[Clinical significance of echography in the diagnosis of portal circulatory disorders]. | Forty-one patients with the endoscopically diagnosed varicose veins of the esophagus and stomach were examined. The echograms of 32 patients with liver cirrhosis showed the impoverishment of the vascular pattern of the liver parenchyma, dilatation of the portal, superior mesenterial and splenic veins, enlargement of th... | ['Adult', 'Aged', 'Cholestasis', 'Common Bile Duct Neoplasms', 'Humans', 'Hypertension, Portal', 'Liver Cirrhosis', 'Mesenteric Veins', 'Middle Aged', 'Pancreatic Neoplasms', 'Portal System', 'Portal Vein', 'Splenic Vein', 'Ultrasonography', 'Umbilical Veins', 'Vascular Diseases'] | 3,518,124 | [['M01.060.116'], ['M01.060.116.100'], ['C06.130.120.135'], ['C04.588.274.120.250.250', 'C06.130.120.120.280', 'C06.130.120.250.280', 'C06.130.320.120.280', 'C06.301.120.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.494'], ['C06.552.630', 'C23.550.355.412'], ['A07.015.908.670.385'], ['M01.060.11... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Changes in the adhesive phenotype of regional lymphocytes in rats with adjuvant arthritis: alteration by cyclophosphamide. | A quantitative spectrophotometrical method was used to study the adhesive phenotype of lymphocytes from regional lymph nodes of rats with early stage adjuvant-induced arthritis (AA), pretreated or not with cyclophosphamide (CY). The results showed that adhesion of lymphocytes from AA-sensitized lymph nodes to gelatin a... | ['Animals', 'Arthritis, Experimental', 'Cell Adhesion', 'Cyclophosphamide', 'Lymph Nodes', 'Lymphocytes', 'Male', 'Phenotype', 'Rats', 'Rats, Inbred Strains', 'Time Factors'] | 1,875,775 | [['B01.050'], ['C05.550.114.015', 'E05.598.500.249'], ['G04.022'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['A10.549.400', 'A15.382.520.604.412'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['G05.695'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.76... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Construction of the discourse on dengue fever in the media. | The aim of this paper was to understand how the media in the state of Pernambuco portrays dengue fever, a disease that is affecting more and more Brazilians. Taking the explosive epidemic of 2002 as the starting point, we tried to understand the effects of meaning produced by the press in a comparative discourse strate... | ['Brazil', 'Dengue', 'Humans', 'Journalism', 'Newspapers as Topic'] | 22,450,493 | [['Z01.107.757.176'], ['C01.920.500.270', 'C01.925.081.270', 'C01.925.782.350.250.214', 'C01.925.782.417.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.737.498'], ['L01.178.682.829.481']] | ['Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations. | Amyotrophic lateral sclerosis (ALS) is a fatal, adult-onset, progressive neurodegenerative disorder with no known cure. Cu/Zn-superoxide dismutase (SOD1) was the first identified protein associated with familial ALS (fALS). Recently, TAR DNA-binding protein 43 (TDP-43) has been found to be a principal component of ubiq... | ['Amyotrophic Lateral Sclerosis', 'Animals', 'Cell Line', 'DNA-Binding Proteins', 'Disease Models, Animal', 'Humans', 'Mice', 'Motor Neurons', 'Mutation', 'Nerve Degeneration', 'Neuroglia', 'Phosphorylation', 'Superoxide Dismutase-1'] | 29,982,983 | [['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['B01.050'], ['A11.251.210'], ['D12.776.260'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['A08.675.655.500', 'A11.671.6... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association between side air bags and risk of injury in motor vehicle collisions with near-side impact. | BACKGROUND: Side air bags (SABs) have been introduced in an attempt to reduce the risk of injury in near-side-impact motor vehicle collisions (MVCs). The impact of SABs on MVC-related mortality and morbidity has yet to be evaluated with a large population-based study. The objective of this study was to assess the effec... | ['Accidents, Traffic', 'Adult', 'Air Bags', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Risk Factors', 'Wounds and Injuries'] | 14,501,882 | [['N06.850.135.392'], ['M01.060.116'], ['E07.700.100', 'J01.637.708.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.82... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Overexpression of amyloid precursor protein increases copper content in HEK293 cells. | Amyloid precursor protein (APP) is a transmembrane glycoprotein widely expressed in mammalian tissues and plays a central role in Alzheimer's disease. However, its physiological function remains elusive. Cu(2+) binding and reduction activities have been described in the extracellular APP135-156 region, which might be r... | ['Amyloid beta-Protein Precursor', 'Cell Line', 'Copper', 'Homeostasis', 'Humans', 'Oxidation-Reduction', 'Peptide Fragments'] | 19,318,086 | [['D12.776.049.407.249', 'D12.776.543.039', 'D12.776.645.468.500', 'D12.776.811.050'], ['A11.251.210'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['G07.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.700', 'G03.295.531'], ['D12.644.541']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A novel forward projection-based metal artifact reduction method for flat-detector computed tomography. | Metallic implants generate streak-like artifacts in flat-detector computed tomography (FD-CT) reconstructed volumetric images. This study presents a novel method for reducing these disturbing artifacts by inserting discarded information into the original rawdata using a three-step correction procedure and working direc... | ['Algorithms', 'Artifacts', 'Brain', 'Cadaver', 'Computer Graphics', 'Computers', 'Humans', 'Metals', 'Models, Statistical', 'Pattern Recognition, Automated', 'Phantoms, Imaging', 'Radiographic Image Interpretation, Computer-Assisted', 'Reproducibility of Results', 'Tomography, X-Ray Computed'] | 19,826,202 | [['G17.035', 'L01.224.050'], ['E05.047'], ['A08.186.211'], ['C23.550.260.224'], ['L01.224.108', 'L01.296.110'], ['L01.224.230.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.552'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['L01.399.750'], ['E07.671'], ['E01.158.600... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Lysis of osteoblastic lesions in prostatic cancer: a sign of progression. | Osteoblastic metastases from prostatic cancer often increase in density after successful endocrine treatment. Regrowth of malignancy, at the time of relapse, may cause osteolytic changes in previously stable sclerotic lesions. Four illustrative case reports are presented. Fading of sclerotic lesions on radiographs, acc... | ['Adenocarcinoma', 'Aged', 'Bone Neoplasms', 'Humans', 'Male', 'Middle Aged', 'Osteoma, Osteoid', 'Prostatic Neoplasms', 'Radiography'] | 6,609,604 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['C04.588.149', 'C05.116.231'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.450.565.575.625.625'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E01.370.350.700']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bacteriology of chronic maxillary sinusitis in relation to sinoscopic appearance. | BACKGROUND: The bacteriology of chronic maxillary sinusitis in relation to different sinoscopic appearances is reported in this study.METHODS: When transantral sinoscopy via an anterior wall puncture was used to examine the maxillary antra in patients with chronic maxillary sinusitis, the sinoscopic appearances were di... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bacteria, Aerobic', 'Bacteria, Anaerobic', 'Child', 'Chronic Disease', 'Endoscopy', 'Female', 'Humans', 'Male', 'Maxillary Sinusitis', 'Middle Aged', 'Nasal Mucosa', 'Retrospective Studies', 'Specimen Handling'] | 12,422,968 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B03.120'], ['B03.130'], ['M01.060.406'], ['C23.550.291.500'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.748.749.578', 'C08.460.692.752.578', 'C08.730.749.578', 'C09.603.692.752.578'], ['M0... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A central circuit of the mind. | The methodologies of cognitive architectures and functional magnetic resonance imaging can mutually inform each other. For example, four modules of the ACT-R (adaptive control of thought - rational) cognitive architecture have been associated with four brain regions that are active in complex tasks. Activity in a later... | ['Basal Ganglia', 'Brain', 'Brain Mapping', 'Caudate Nucleus', 'Cognition', 'Gyrus Cinguli', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Magnetic Resonance Imaging', 'Mental Recall', 'Nerve Net', 'Neural Networks, Computer', 'Parietal Lobe', 'Prefrontal Cortex', 'Problem Solving', 'T... | 18,329,948 | [['A08.186.211.200.885.287.249'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.249.487.550.184'], ['F02.463.188'], ['A08.186.211.180.590.500', 'A08.186.211.200.885.287.500.382.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308']... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Action plan for a tobacco-free Europe: implementation in central and eastern Europe, 1993-94. WHO Regional Office for Europe. | Major political and social changes in central and eastern European (CEE) countries offer new opportunities and challenges in tobacco control. Action against tobacco in CEE countries is part of an overall European strategy, the action plan for a tobacco-free Europe. Several CEE countries have voiced their concern about ... | ['Environmental Health', 'Europe', 'Europe, Eastern', 'Health Education', 'Health Planning', 'Health Policy', 'Health Promotion', 'Humans', 'Information Services', 'Plants, Toxic', 'Policy Making', 'Smoke', 'Smoking Cessation', 'Smoking Prevention', 'Tobacco', 'World Health Organization'] | 8,461,862 | [['H02.229'], ['Z01.542'], ['Z01.542.248'], ['I02.233.332', 'N02.421.726.407'], ['N03.349', 'N03.706.615.302'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453'], ['B01.650.660'], ['N03.706.... | ['Disciplines and Occupations [H]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
Giving voice to the lifeworld. More humane, more effective medical care? A qualitative study of doctor-patient communication in general practice. | Mishler (The discourse of medicine. The dialectics of medical interviews. Norwood, NJ: Ablex), applying Habermas's theory of Communicative Action to medical encounters. showed how the struggle between the voice of medicine and the voice of the lifeworld fragmented and suppressed patients' multi-faceted, contextualised ... | ['Adult', 'Aged', 'Communication', 'Family Practice', 'Female', 'Holistic Health', 'Humans', 'Male', 'Medical History Taking', 'Middle Aged', 'Patient Participation', 'Patient-Centered Care', 'Physician-Patient Relations'] | 11,459,399 | [['M01.060.116'], ['M01.060.116.100'], ['F01.145.209', 'L01.143'], ['H02.403.340.500'], ['E02.190.321', 'K01.752.667.710', 'N01.400.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.510'], ['M01.060.116.630'], ['F01.100.150.750.500.620', 'F01.145.488.887.500.620', 'N02.421.143.212.300', 'N03.540.245.360... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Electrogenerated chemiluminescence of ZnO nanorods and its sensitive detection of cytochrome C. | Various kinds of ZnO nanoparticles have been successfully used in gas sensing applications, however, these nanomaterials have been rarely investigated in electrogenerated chemiluminescence (ECL). In the present work, ZnO nanorods (ZnONRs) were synthesized by hydrothermal method, and characterized by field emission scan... | ['Cytochromes c', 'Electrochemical Techniques', 'Electrodes', 'Humans', 'Hydrogen-Ion Concentration', 'Limit of Detection', 'Luminescence', 'Luminescent Measurements', 'Metal Nanoparticles', 'Nanotubes', 'Potassium Compounds', 'Sulfates', 'Zinc Oxide'] | 29,310,213 | [['D08.244.286.100', 'D12.776.422.220.286.100'], ['E05.301'], ['E07.305.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.750.250.650.665', 'G01.750.770.578.665'], ['E05.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.