Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Mechanism of nasal absorption of drugs. II: Absorption of L-tyrosine and the effect of structural modification on its absorption. | The nasal absorption of L-tyrosine and the effect of structural modification on that absorption have been studied using an in-situ experimental technique. The extent of nasal absorption of the amino acid was found to be the same at pH values of 4.0 and 7.4 but dependent on concentration in the range of 2.8 X 10(-4)-2.2... | ['Absorption', 'Animals', 'Hydrogen-Ion Concentration', 'Hydrolysis', 'Kinetics', 'Male', 'Nasal Mucosa', 'Rats', 'Rats, Inbred Strains', 'Solubility', 'Tyrosine'] | 4,087,196 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['B01.050'], ['G02.300'], ['G02.380'], ['G01.374.661', 'G02.111.490'], ['A04.531.520', 'A04.760.600', 'A10.615.550.760.600'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['G... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Uptake of dehydroepiandrosterone-3-sulfate by isolated trophoblasts from human term placenta, JEG-3, BeWo, Jar, BHK cells, and BHK cells transfected with human sterylsulfatase-cDNA. | The human placenta lacks the enzyme 17alpha-hydroxylase/17-20-lyase, and is thus unable to convert cholesterol into estrogens. Therefore estrogen synthesis of trophoblast cells depends on the supply of precursors such as dehydroepiandrosterone-3-sulfate (DHEA-S) and 16alpha-hydroxy-dehydroepiandrosterone-3-sulfate by m... | ['Arylsulfatases', 'Biological Transport', 'Cell Line', 'DNA, Complementary', 'Dehydroepiandrosterone Sulfate', 'Female', 'Humans', 'Kinetics', 'Placenta', 'Steryl-Sulfatase', 'Taurocholic Acid', 'Transfection', 'Trophoblasts', 'Tumor Cells, Cultured'] | 10,704,909 | [['D08.811.277.352.827.070'], ['G03.143'], ['A11.251.210'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D04.210.500.054.079.429.625.300', 'D04.210.500.578.502.400.300', 'D06.472.040.502.400.300', 'D06.472.334.851.968.952.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evolution of distinct EGF domains with specific functions. | EGF domains are extracellular protein modules cross-linked by three intradomain disulfides. Past studies suggest the existence of two types of EGF domain with three-disulfides, human EGF-like (hEGF) domains and complement C1r-like (cEGF) domains, but to date no functional information has been related to the two differe... | ['Amino Acid Sequence', 'Complement C1r', 'Databases, Protein', 'Epidermal Growth Factor', 'Evolution, Molecular', 'Glycosylation', 'Humans', 'Hydroxylation', 'Intracellular Signaling Peptides and Proteins', 'Latent TGF-beta Binding Proteins', 'Models, Molecular', 'Molecular Sequence Data', 'Protein Structure, Tertiary... | 15,772,310 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D08.811.277.300.280', 'D12.776.124.486.274.045.280', 'D12.776.124.486.274.050.280'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.46... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[The Spanish Society of Cytology: Quality control program of gynecological cytology]. | INTRODUCTION: In Spain, the guidelines for cervical cancer screening include a recommendation to enroll in external quality control programs. The Spanish Society of Cytology (SEC) has initiated its own quality control program of gynecological cytology (QCPGC).AIM: To describe and discuss the results of the second round... | ['Cytodiagnosis', 'Female', 'Genital Diseases, Female', 'Humans', 'Program Evaluation', 'Quality Control', 'Societies, Medical', 'Spain'] | 29,602,377 | [['E01.370.225.500.384', 'E05.200.500.384', 'E05.242.384'], ['C13.351.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['J01.897.608'], ['N03.540.828.589'], ['Z01.542.846']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Quantification of radioactivity by planar gamma-camera images, a promoted method of absorbed dose in the thyroid after iodine-131 treatment. | Iodine-131 (131I) is an essential and widely used radioisotope in thyroid diseases and animal experiments. Planar imaging has been considered the most popular method for 131I thyroid uptake radioactive activity quantification. The ROI defining section is essential and can affect the accuracy of quantitative results. Ho... | ['Absorption, Radiation', 'Animals', 'Dose-Response Relationship, Radiation', 'Iodine Radioisotopes', 'Male', 'Models, Biological', 'Radioactivity', 'Radionuclide Imaging', 'Rats, Sprague-Dawley', 'Reference Standards', 'Thyroid Gland'] | 29,977,082 | [['G01.015.249.500', 'G01.750.124', 'G02.010.500.500'], ['B01.050'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['E05.599.395'], ['G01.828'], ['E01.370.350.710', 'E01.370.384.730'], ['B01.050.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Optic cup and facial patterning defects in ocular ectoderm beta-catenin gain-of-function mice. | BACKGROUND: The canonical Wnt signaling pathway has a number of critical functions during embryonic development and, when activated aberrantly, in the genesis of cancer. Current evidence suggests that during eye development, regulation of Wnt signaling is critical for patterning the surface ectoderm that will contribut... | ['Animals', 'Body Patterning', 'Ectoderm', 'Embryo, Mammalian', 'Face', 'Gene Expression Regulation, Developmental', 'Lens, Crystalline', 'Mice', 'Mice, Transgenic', 'Mutation', 'Signal Transduction', 'Time Factors', 'Transgenes', 'Wnt Proteins', 'beta Catenin'] | 16,539,717 | [['B01.050'], ['G07.345.500.100'], ['A16.504.273'], ['A16.254'], ['A01.456.505'], ['G05.308.310'], ['A09.371.060.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['G05.365.590'], ['G02.111.820', 'G04.835'], ['G01.910.857'], ['G05.360.340.024.340... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Social problem-solving in depressed, conduct-disordered, and normal adolescents. | Although past theory and research implicate social problem-solving deficits in both depression and aggressive disorders, research examining carefully diagnosed groups of adolescent depressed and conduct-disordered groups had not previously been conducted. In the current study three groups of adolescents (major depressi... | ['Adolescent', 'Aggression', 'Depressive Disorder', 'Female', 'Humans', 'Male', 'Personality Development', 'Personality Inventory', 'Problem Solving', 'Social Behavior'] | 2,266,226 | [['M01.060.057'], ['F01.145.126.125', 'F01.145.813.045'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.747'], ['F04.711.647.513'], ['F02.463.425.725', 'F02.463.785.810'], ['F01.145.813']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
White blood cell-reduced platelet concentrates prepared by filtration using the Sepacell PL 5 II/10 II filter. | The further developed adsorption filter Sepacell PL 5/10 II has been evaluated for the white blood cell (WBC) removal from platelet concentrates (PCs) collected using a blood cell separator Fresenius AS 104 (F) or Haemonetics PCS Plus (H). Filtration was carried out according to the manufacturer's instructions by gravi... | ['Cytapheresis', 'Filtration', 'Humans', 'Leukocytes', 'Plateletpheresis'] | 9,422,102 | [['E02.095.160', 'E02.120.285', 'E05.200.500.363.171', 'E05.242.363.171'], ['E05.196.454', 'G01.280', 'G02.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['E02.095.160.790', 'E02.120.285.790', 'E05.200.500.363.171.790', 'E05.242.363.171.790']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of total and direct bilirubins in serum with sodium dodecyl sulfate as an accelerator. | A new method for the determination of total and conjugated bilirubins in serum with use of sodium dodecyl sulfate (SDS) is described. In the presence of SDS, the reaction of bilirubin with diazotized sulfanilic acid proceeded smoothly and was completed within 15 min at room temperature, thus resulting in a clear soluti... | ['Ascorbic Acid', 'Azo Compounds', 'Bilirubin', 'Humans', 'Methods', 'Sodium Dodecyl Sulfate'] | 679,483 | [['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['D02.172'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['D02.033.415.220.720', 'D02.886.645.600.055.050.632', 'D10.289.220.720']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Limitations to the use of a sensitive assay for serum thyrotropin in the assessment of thyroid status. | In the majority of clinical settings, a suppressed serum thyrotropin (s-TSH) level determined by the new sensitive assays is diagnostic of thyrotoxicosis. This has led to its proposed use as a screen for thyroid disease. However, s-TSH may be suppressed in conditions other than thyrotoxicosis. We retrospectively review... | ['Adult', 'Aged', 'Female', 'Humans', 'Hyperthyroidism', 'Hypothyroidism', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Retrospective Studies', 'Thyroid Diseases', 'Thyroid Hormones', 'Thyrotropin'] | 2,916,881 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.397'], ['C19.874.482'], ['M01.060.116.630'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Developmental changes in multispecific organic anion transporter 1 expression in the rat kidney. | BACKGROUND: The cDNA of the multispecific organic anion transporter 1 (OAT1) responsible for the tubular secretion of organic anions was recently isolated. In the current study, we investigated the developmental changes in OAT1 expression in the rat kidney.METHODS: Ontogenic expression of rat OAT1 was investigated by N... | ['Aging', 'Animals', 'Animals, Newborn', 'Anion Transport Proteins', 'Blotting, Northern', 'Blotting, Western', 'Carrier Proteins', 'Immunohistochemistry', 'In Situ Hybridization', 'In Vitro Techniques', 'Kidney', 'Male', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'p-Aminohippuric Acid'] | 10,760,096 | [['G07.345.124'], ['B01.050'], ['B01.050.050.282'], ['D12.776.157.530.450.074', 'D12.776.543.585.450.074'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.157'], ['E01.370.225.500.607.512', 'E01.370.22... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Neuropsychiatric disorders in algodysmenorrhea in puberty]. | Fifty-two patients with algodysmenorrhea aged 12-16 years were examined with the help of clinical, psychopathologic and psychologic techniques. The author identified the syndrome of fear (n = 22), as well as depressive dysthymic (n = 18) and senestopathic-hypochondriac (n = 12) syndromes. Clinical variability of border... | ['Adolescent', 'Child', 'Dysmenorrhea', 'Female', 'Humans', 'Mental Disorders', 'Nervous System Diseases', 'Neurocognitive Disorders', 'Personality', 'Pregnancy', 'Pregnancy Complications', 'Prenatal Exposure Delayed Effects', 'Puberty', 'Syndrome'] | 3,618,048 | [['M01.060.057'], ['M01.060.406'], ['C23.550.568.750', 'C23.888.592.612.944.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['C10'], ['F03.615'], ['F01.752'], ['G08.686.784.769'], ['C13.703'], ['C13.703.824.500'], ['G08.686.760', 'G08.686.841.374'], ['C23.550.288.500']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Combination of alpha-interferon with lamivudine reduces viral breakthrough during long-term therapy. | BACKGROUND AND AIM: Viral breakthrough is frequently encountered during long-term lamivudine therapy, mostly associated with YMDD mutants. In this study, we investigated the effects of alpha-interferon (IFN-alpha) combined with lamivudine on the occurrence of viral breakthrough during long-term lamivudine therapy.METHO... | ['Adult', 'Antiviral Agents', 'Drug Therapy, Combination', 'Female', 'Hepatitis B, Chronic', 'Humans', 'Interferon-alpha', 'Lamivudine', 'Male', 'Reverse Transcriptase Inhibitors', 'Time Factors'] | 15,610,309 | [['M01.060.116'], ['D27.505.954.122.388'], ['E02.319.310'], ['C01.221.250.500.100', 'C01.925.256.430.400.100', 'C01.925.440.435.100', 'C06.552.380.350.100', 'C06.552.380.705.437.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890.250', 'D12.776.467.374.440.890.250', 'D23.529.374.440.890.25... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Optimization of lipase-catalyzed biodiesel by isopropanolysis in a continuous packed-bed reactor using response surface methodology. | Isopropanolysis reactions were performed using triglycerides with immobilized lipase in a solvent-free environment. This study modeled the degree of isopropanolysis of soybean oil in a continuous packed-bed reactor when Novozym 435 was used as the biocatalyst. Response surface methodology (RSM) and three-level-three-fa... | ['2-Propanol', 'Analysis of Variance', 'Biocatalysis', 'Biofuels', 'Bioreactors', 'Biotechnology', 'Conservation of Natural Resources', 'Esters', 'Lipase', 'Models, Biological', 'Reproducibility of Results', 'Rheology', 'Temperature'] | 19,646,554 | [['D02.033.755.615'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G02.111.086', 'G02.130.500', 'G03.105'], ['D20.147', 'N06.230.132.644.124'], ['E07.115', 'J01.897.120.115'], ['H01.158.550', 'J01.897.120'], ['J01.256', 'N06.230.080'], ['D02.241.400'], ['D08.811.277.352.100.400'], ['E05.599.395'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Functional significance of the mandibular symphysis. | The purpose of this investigation was to relate the morphology of connective tissues in the mandibular symphysis to the behavioral and experimental evidence for mobility and mechanical stress at the symphysis. The anatomy of the symphysis was examined histologically in 6 mammalian orders encompassing 22 species. Behavi... | ['Animals', 'Cineradiography', 'Connective Tissue', 'Dental Stress Analysis', 'Ligaments', 'Mammals', 'Mandible', 'Mastication', 'Masticatory Muscles', 'Movement', 'Periosteum', 'Rats', 'Species Specificity', 'Stress, Mechanical', 'Tensile Strength', 'Tooth'] | 423,251 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sorting nexin 17 regulates ApoER2 recycling and reelin signaling. | ApoER2 is a member of the low density-lipoprotein receptor (LDL-R) family. As a receptor for reelin, ApoER2 participates in neuronal migration during development as well as synaptic plasticity and survival in the adult brain. A previous yeast two-hybrid screen showed that ApoER2 is a binding partner of sorting nexin 17... | ['Amyloid Precursor Protein Secretases', 'Animals', 'Cell Adhesion Molecules, Neuronal', 'Escherichia coli', 'Extracellular Matrix Proteins', 'Flow Cytometry', 'HEK293 Cells', 'HeLa Cells', 'Humans', 'Immunoprecipitation', 'LDL-Receptor Related Proteins', 'Lentivirus', 'Nerve Tissue Proteins', 'Neurons', 'Rats', 'Serin... | 24,705,369 | [['D08.811.277.656.300.032'], ['B01.050'], ['D12.776.395.550.200.250', 'D12.776.543.550.200.250', 'D23.050.301.350.250'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.860.300'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Anxiolytic effect of the dehydroepiandrosterone sulfate: mu-opioid mechanism]. | Effects of dehydroepiandrosterone sulfate (DHEAS, 30 mg/kg, i/p, 4 and 28 hours after injection) on CBA/Lac male mice with increased level of anxiety resulting from chronic (20-days) social confrontations in two behavioral anxiety-estimated tests, were studied. The anxiolytic effect of DHEAS was discovered within 4 hou... | ['Aggression', 'Animals', 'Anti-Anxiety Agents', 'Anxiety', 'Competitive Behavior', 'Dehydroepiandrosterone Sulfate', 'Dominance-Subordination', 'Male', 'Mice', 'Mice, Inbred CBA', 'Mice, Inbred Strains', 'Naltrexone', 'Narcotic Antagonists', 'Receptors, Opioid, mu', 'Social Dominance', 'Stress, Psychological'] | 14,502,980 | [['F01.145.126.125', 'F01.145.813.045'], ['B01.050'], ['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['F01.470.132'], ['F01.145.813.105'], ['D04.210.500.054.079.429.625.300', 'D04.210.500.578.502.400.300', 'D06.472.040.502.400.300', 'D06.472.334.851.968.952.300'], ['F01.145.8... | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Autoradiography of the olfactory-hippocampal pathway in the cat with special reference to the perforant path. | The anatomical pathway from the prepyriform cortex to the hippocampus in the cat was traced autoradiographically by means of anterograde transport of [3H] leucine. A direct projection from the prepyriform cortex to the lateral entorhinal area was confirmed in the cat: the termination of these fibers was largely confine... | ['Animals', 'Autoradiography', 'Cats', 'Central Nervous System', 'Cerebral Cortex', 'Dendrites', 'Hippocampus', 'Neural Pathways', 'Olfactory Pathways'] | 7,371,730 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.186'], ['A08.186.211.200.885.287.500'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['A08.612'], ['A08.186.211.180.699', 'A08... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fractal characterisation of boundary irregularity in skin pigmented lesions. | A growing literature shows researcher's interest in fractal analysis, arising from its ability to describe and characterise quantitatively the complexity of several tumour profiles. The aim of the work was to investigate the fractal properties of skin pigmented lesion boundaries. Although melanoma is one of the most ag... | ['Diagnosis, Differential', 'Fractals', 'Humans', 'Image Processing, Computer-Assisted', 'Melanoma', 'Nevus, Pigmented', 'Skin Diseases'] | 16,255,424 | [['E01.171'], ['E05.599.125', 'G17.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['C04.557.665.560.615'], ['C17.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Canalization of Language Structure From Environmental Constraints: A Computational Model of Word Learning From Multiple Cues. | There is substantial variation in language experience, yet there is surprising similarity in the language structure acquired. Constraints on language structure may be external modulators that result in this canalization of language structure, or else they may derive from the broader, communicative environment in which ... | ['Algorithms', 'Computer Simulation', 'Cues', 'Environment', 'Humans', 'Language Development', 'Models, Psychological', 'Verbal Learning'] | 27,989,019 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['F02.463.425.234'], ['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.525.200.310'], ['E05.599.695'], ['F02.463.425.952']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Influence of auto-cross-linked hyaluronic acid gel on pregnancy rate and hysteroscopic outcomes following surgical removal of intra-uterine adhesions. | OBJECTIVE: To determine the effect of the use of auto-cross-linked hyaluronic acid (ACP) gel following hysteroscopic surgery on the prevention of intra-uterine adhesions (IUAs) and the pregnancy rate.STUDY DESIGN: An observational retrospective study of 90 patients who underwent hysteroscopic removal of IUAs was conduc... | ['Adult', 'Case-Control Studies', 'Female', 'Follow-Up Studies', 'Gels', 'Humans', 'Hyaluronic Acid', 'Hysteroscopy', 'Infertility, Female', 'Polysaccharides', 'Pregnancy', 'Pregnancy Rate', 'Recurrence', 'Retrospective Studies', 'Severity of Illness Index', 'Tissue Adhesions', 'Uterine Diseases'] | 26,246,163 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D20.280.320', 'D26.255.165.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.475'], ['E01.370.378.330', 'E01.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dietary cholesterol and its effect on tau protein: a study in apolipoprotein E-deficient and P301L human tau mice. | Apolipoprotein E (ApoE) is the major cholesterol transporter in the brain. There is epidemiological and experimental evidence for involvement of cholesterol metabolism in the development and progression of Alzheimer disease. A dietary effect on tau phosphorylation or aggregation, or a role of apoE in tau metabolism, ha... | ['Animals', 'Apolipoproteins E', 'Brain Chemistry', 'Cell Count', 'Cholesterol', 'Cholesterol, Dietary', 'Diet', 'Genotype', 'Humans', 'Immunohistochemistry', 'Lipids', 'Mice', 'Mice, Knockout', 'Mice, Transgenic', 'Phosphorylation', 'Protein Conformation', 'tau Proteins'] | 21,412,171 | [['B01.050'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['G02.111.150', 'G03.185'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.225', 'D10.212.302.347', 'D10.570.938.20... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Basement membrane components are potent promoters of rat intestinal epithelial cell differentiation in vitro. | Basement membranes have been implicated in morphogenesis and cell differentiation. In this study, the effect of basement membrane components on intestinal epithelial cell maturation in a mesenchyme-free environment was investigated. Fetal rat small intestinal epithelial cells (from the 14th-17th day of gestation) were ... | ['Animals', 'Basement Membrane', 'Cell Differentiation', 'Cell Division', 'Collagen', 'Epithelial Cells', 'Extracellular Matrix', 'In Vitro Techniques', 'Intestine, Small', 'Membrane Glycoproteins', 'Microvilli', 'Rats', 'Rats, Inbred Strains'] | 2,295,387 | [['B01.050'], ['A10.272.220', 'A10.615.179'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D05.750.078.280', 'D12.776.860.300.250'], ['A11.436'], ['A11.284.295.310'], ['E05.481'], ['A03.556.124.684'], ['D12.776.395.550', 'D12.776.543.550'], ['A11.284.180.565'], ['B01.050.150.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Borrelia sp. in the common tick (Ixodes ricinus) from the Prague area]. | In the course of 1988 almost 3000 ticks were collected from various localities on the territory of Prague and examined by the method of indirect immunofluorescence (IFA) for the presence of Borrelia. The immunity rate of ticks varies between 1.9-22.0%. Positive ticks were found also in some areas practically in the cen... | ['Animals', 'Borrelia', 'Czechoslovakia', 'Ticks'] | 2,139,810 | [['B01.050'], ['B03.440.425.410.711.193', 'B03.851.595.193'], ['Z01.586.250'], ['B01.050.500.131.166.132.832']] | ['Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Beta2-microglobulin levels of serum and ascites in malignant diseases. | Serum beta2-microglobulin levels were measured by radioimmunoassay in patients with various malignant neoplasms, ascitic patients, and also patients with definite or suspected hepatoma showing variable levels of serum alpha-fetoprotein. Elevated serum beta2-microglobulin levels greater than 2.5 mg/liter were found in v... | ['Adult', 'Ascitic Fluid', 'Beta-Globulins', 'Carcinoma, Hepatocellular', 'Female', 'Humans', 'Liver Neoplasms', 'Male', 'Multiple Myeloma', 'Neoplasms', 'Radioimmunoassay', 'alpha-Fetoproteins', 'beta 2-Microglobulin'] | 80,342 | [['M01.060.116'], ['A12.207.119'], ['D12.776.124.790.223', 'D12.776.377.715.182'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['C04.557.595.500', 'C14.907.454.460', 'C15.378... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Discovery of (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2-(dimethylamino)ethanone (CHMFL-FLT3-122) as a Potent and Orally Available FLT3 Kinase Inhibitor for FLT3-ITD Positive Acute Myeloid Leukemia. | FLT3-ITD mutant has been observed in about 30% of AML patients and extensively studied as a drug discovery target. On the basis of the structure of PCI-32765 (ibrutinib), a BTK kinase inhibitor that was recently reported to bear FLT3 kinase activity through a structure-guided drug design approach, we have discovered co... | ['Administration, Oral', 'Animals', 'Antineoplastic Agents', 'Biological Availability', 'Cell Line, Tumor', 'Drug Screening Assays, Antitumor', 'Female', 'Heterografts', 'Humans', 'Leukemia, Myeloid, Acute', 'Male', 'Mice, Nude', 'Molecular Docking Simulation', 'Mutation', 'Neoplasm Transplantation', 'Pyrazoles', 'Pyri... | 26,630,553 | [['E02.319.267.100'], ['B01.050'], ['D27.505.954.248'], ['G03.787.151', 'G07.690.725.129'], ['A11.251.210.190', 'A11.251.860.180'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['A01.941.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.275'], ['B01.050.150.900.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Substrate-dependent differences in growth and biological properties of fibroblasts and epithelial cells grown in microcarrier culture. | Normal diploid human fibroblasts and first passage monkey kidney epithelial cells were examined for growth and metabolic activity on microcarriers made from glass and on microcarriers made from DEAE-dextran. The cells grew to a higher density (cells cm2 of surface area) on the glass microcarriers made from glass and on... | ['Animals', 'Cells, Cultured', 'Chlorocebus aethiops', 'Cytological Techniques', 'DEAE-Dextran', 'Epithelial Cells', 'Fibroblasts', 'Humans', 'Microscopy, Electron, Scanning', 'Peptide Hydrolases', 'Prostaglandin-Endoperoxide Synthases', 'Prostaglandins', 'Simplexvirus', 'Substrate Specificity', 'Time Factors', 'Trypsi... | 2,985,616 | [['B01.050'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['E01.370.225.500', 'E05.200.500', 'E05.242'], ['D09.698.365.272.250'], ['A11.436'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D08.811.277.656'], ['D08.811.600.72... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domain. | Emerging data have indicated that hepatitis C virus (HCV) subverts the host antiviral response to ensure its persistence. We previously demonstrated that HCV protein expression suppresses type I interferon (IFN) signaling by leading to the reduction of phosphorylated STAT1 (P-STAT1). We also demonstrated that HCV core ... | ['Cell Line, Tumor', 'Hepacivirus', 'Humans', 'Interferons', 'Models, Genetic', 'Phosphorylation', 'Point Mutation', 'Protein Binding', 'Protein Structure, Tertiary', 'STAT1 Transcription Factor', 'Signal Transduction', 'Transcription, Genetic', 'Viral Core Proteins', 'src Homology Domains'] | 16,940,534 | [['A11.251.210.190', 'A11.251.860.180'], ['B04.450.380', 'B04.820.578.344.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440', 'D12.776.467.374.440', 'D23.529.374.440'], ['E05.599.395.397'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['G05.365.590.675'], ['G02.111.679', 'G03.808'], ['G02.111.... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Obesity prevalence among healthcare professionals in England: a cross-sectional study using the Health Survey for England. | OBJECTIVE: To estimate obesity prevalence among healthcare professionals in England and compare prevalence with those working outside of the health services.DESIGN: Cross-sectional study based on data from 5 years (2008-2012) of the nationally representative Health Survey for England.SETTING: England.PARTICIPANTS: 20 1... | ['Adult', 'Body Mass Index', 'Cross-Sectional Studies', 'England', 'Female', 'Health Personnel', 'Health Surveys', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Obesity', 'Prevalence', 'Socioeconomic Factors', 'Young Adult'] | 29,203,505 | [['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542.363.300'], ['M01.526.485', 'N02.360'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Rearrangements and addition reactions of biarylazacyclooctynones and the implications to copper-free click chemistry. | Highly strained biarylazacyclooctynone (BARAC) and analogous bioconjugation reagents were shown to undergo novel rearrangement and addition reactions leading to tetracyclic products. This may limit their practical applicability as bioorthogonal reporters for imaging biomolecules within living systems. | ['Aza Compounds', 'Click Chemistry', 'Copper', 'Cyclization', 'Magnetic Resonance Spectroscopy', 'Molecular Structure', 'Nitrogen Oxides'] | 23,629,512 | [['D02.145'], ['E05.197.124', 'J01.897.836.249.124'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['G02.111.180', 'G02.607.133', 'G03.208'], ['E05.196.867.519'], ['G02.111.570', 'G02.466'], ['D01.362.635', 'D01.625.550', 'D01.650.550.587']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Determination of the circulation in the human retina using image analysis of video-angiograms]. | A method is described to determine the total retinal blood flow. Intravenous fluorescence angiography is the clinical procedure used, together with digital image processing methods. Our system consists of a standard fundus camera, a highly sensitive sensor with a low-light-level intensifier (micro-channal plate) and a ... | ['Blood Flow Velocity', 'Fluorescein Angiography', 'Humans', 'Image Processing, Computer-Assisted', 'Retinal Artery', 'Retinal Diseases', 'Video Recording'] | 2,737,572 | [['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['A07.015.114.765', 'A07.015.611.647'], ['C11.768'], ['L01.280.960']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Tryptophan and depressive illness. | Plasma free tryptophan is significantly decreased in monopolar, depressed patients. No evidence was found to suggest that poor nutritional history prior to hospital admission was responsible for these low levels. Factors known to influence tryptophan-albumin binding in plasma, e.g. concentration of plasma proteins, alb... | ['Blood Proteins', 'Clinical Trials as Topic', 'Clofibrate', 'Depression', 'Dietary Proteins', 'Double-Blind Method', 'Estrogens, Conjugated (USP)', 'Fatty Acids, Nonesterified', 'Female', 'Humans', 'Menopause', 'Middle Aged', 'Protein Binding', 'Tryptophan'] | 204,954 | [['D12.776.124'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D02.241.081.114.968.500.500.195', 'D02.355.726.305.500.195', 'D02.455.426.559.389.657.654.305.500.195'], ['F01.145.126.350'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['E05.318.370.300', 'E05.581.500.300', 'N05.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
[A case of multiple myeloma showing intracranial hypertension due to large cranial mass lesions]. | It is well known that the case of multiple myeloma shows punched-out lesions of the cranium without intracranial hypertension. In this paper a case of multiple myeloma is reported showing intracranial hypertension due to a large tumor that developed in the left parietal bone. There are only 13 case reports about crania... | ['Female', 'Humans', 'Middle Aged', 'Multiple Myeloma', 'Parietal Bone', 'Pseudotumor Cerebri', 'Skull Neoplasms'] | 3,756,028 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.595.500', 'C14.907.454.460', 'C15.378.147.780.650', 'C15.378.463.515.460', 'C20.683.515.845', 'C20.683.780.650'], ['A02.835.232.781.651'], ['C10.228.140.631.750'], ['C04.588.149.721', 'C05.116.231.754']] | ['Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Combination of propofol-sufentanil on somatosensory evoked potentials in surgery of the spine]. | OBJECTIVES: Most anaesthetics depress cortical somatosensory evoked potentials (CSEPs). However, the modification of CSEPs during total intravenous anaesthesia using propofol remaining still unknown, justified this trial.TYPE OF STUDY: Open, prospective, clinical study.METHODS: Nine consecutive patients requiring CSEPs... | ['Adult', 'Aged', 'Analgesics, Opioid', 'Anesthetics, Intravenous', 'Evoked Potentials, Somatosensory', 'Humans', 'Middle Aged', 'Monitoring, Intraoperative', 'Propofol', 'Prospective Studies', 'Spine', 'Sufentanil'] | 8,572,387 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['D27.505.696.277.100.035.075', 'D27.505.954.427.210.100.035.075'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Production and Characterization of Nanosilica from Bagasse Through Biosynthesis Using Lactobacilus bulgaricus. | Bagasse has a potential as natural resource of nanosilica. Nanosilica biosynthetic production method is better than chemical or physical methods. The aim of this study is to determine the potential of Lactobacillus bulgaricus in nanosilica synthesis, the effect of the long incubation, and the effect of freeze drying to... | ['Air', 'Cellulose', 'Freeze Drying', 'Lactobacillus', 'Nanoparticles', 'Nanotechnology', 'Silicon Dioxide', 'Temperature'] | 27,427,679 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['E01.370.225.500.620.760.160.260', 'E01.370.225.750.600.760.160.260', 'E02.792.156.260', 'E05.200.500.620.760.160.260', 'E05.200.750.600.760.160.260', 'E05.760.156.260'], ['B03.353... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Regulation of immune complexes during infection of mice with lactate dehydrogenase-elevating virus: studies with interferon-gamma gene knockout and tolerant mice. | Mice persistently infected with lactate dehydrogenase-elevating virus (LDV) develop circulating IgG-containing hydrophobic immune complexes, with a molecular mass of 150 to 300 kd, which bind to the surfaces of high-capacity enzyme-linked immunosorbent assay (ELISA) plates. LDV infection also stimulates polyclonal B-ce... | ['Animals', 'Animals, Newborn', 'Antibodies, Viral', 'Antigen-Antibody Complex', 'Arterivirus Infections', 'Immune Tolerance', 'Immunoglobulin G', 'In Situ Hybridization', 'Interferon-gamma', 'Lactate dehydrogenase-elevating virus', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Viremia', 'Virus Replication'] | 10,413,362 | [['B01.050'], ['B01.050.050.282'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['C01.925.782.600.100'], ['G12.535.425'], ['D12.776.124.486.485.114.619.393', 'D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phonosurgery in gender dysphoria. | A particular type of phonosurgery is voice change surgery in cases of gender dysphoria. This paper presents a review of the surgical techniques available for raising or lowering speaking fundamental frequency. A cricothyroid approximation to raise the vocal pitch is the most common procedure. This procedure results in ... | ['Cricoid Cartilage', 'Humans', 'Male', 'Thyroid Cartilage', 'Transsexualism', 'Voice'] | 10,925,714 | [['A02.165.257.625.211', 'A02.165.407.500.211', 'A04.329.591.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.165.257.625.870', 'A02.165.407.500.870', 'A04.329.591.870'], ['F01.145.802.975.750'], ['G09.772.925']] | ['Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prolonged ventilation and intact survival in very low birth weight infants. | UNLABELLED: A requirement for prolonged ventilation (>28 days) has been associated with a poor outcome in infants. We postulated that in the present population of infants who usually receive antenatal steroids and post-natal surfactant, prolonged ventilation in discrete episodes, i.e. discontinuous intermittent positiv... | ['Chi-Square Distribution', 'Developmental Disabilities', 'Gestational Age', 'Humans', 'Infant Mortality', 'Infant, Newborn', 'Infant, Premature', 'Infant, Very Low Birth Weight', 'Intermittent Positive-Pressure Ventilation', 'Motor Activity', 'Nervous System Diseases', 'Prospective Studies', 'Statistics, Nonparametric... | 12,548,379 | [['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['F03.625.421'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.550.475', 'N01.224.935.698.489', 'N06.850.505.400.975.550.475', 'N06.850.520.308.985.550.475'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Assessment of myocardial viability by using newly developed myocardial SPECT imaging. | Thallium myocardial imaging has been widely available for the detection of myocardial ischemia and assessment of myocardial viability in coronary artery diseases. However, myocardial imaging using SPECT and gamma-emitting radiopharmaceuticals has been developed for accurate evaluation of myocardial infarction and ische... | ['3-Iodobenzylguanidine', 'Aged', 'Coronary Disease', 'Fatty Acids', 'Female', 'Heart', 'Humans', 'Iodine Radioisotopes', 'Iodobenzenes', 'Male', 'Middle Aged', 'Sympathetic Nervous System', 'Tomography, Emission-Computed, Single-Photon'] | 1,625,365 | [['D02.078.370.510', 'D02.455.426.559.389.454.300', 'D02.455.526.581.496.300'], ['M01.060.116.100'], ['C14.280.647.250', 'C14.907.585.250'], ['D10.251'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['D02.455.426.559.389.454', 'D02.455.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Physicians and fund development. Part II. Cultivating donors. Physicians as an essential link. | Physicians have a vested interest in the outcome of philanthropic activities that advance programs and services at your institution. This Top 10 list will help you discover the project or area that excites a physician's passion and ultimately gets them involved in fund development. | ['Altruism', 'Fund Raising', 'Governing Board', 'Hospital Planning', 'Hospitals, Voluntary', 'Humans', 'Interprofessional Relations', "Physician's Role", 'Planning Techniques', 'United States', 'Volunteers'] | 12,048,759 | [['F01.145.813.090'], ['N03.219.463.360'], ['N04.452.394'], ['N03.349.650.250.200'], ['N02.278.421.481.800'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205'], ['F01.829.316.616.625.600'], ['N04.452.718'], ['Z01.107.567.875'], ['M01.955']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cancer treatment summaries and follow-up care instructions: which cancer survivors receive them? | PURPOSE: Medically underserved subgroups of survivors bear a disproportionate burden of cancer-related health problems. Treatment summaries and follow-up care instructions are one possible strategy to address disparities in cancer-related health among cancer survivors. However, it is not known which cancer survivors re... | ['Adolescent', 'Adult', 'Aged', 'Delivery of Health Care', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasms', 'Survivors'] | 23,385,334 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['N04.590.374', 'N05.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Three dimensional structures of pulmonary elastin; airway vs vascular elastin. | Elastin is known to occur in the lung parenchyma and pleura as well as in the pulmonary vessels, but no detailed studies of this elastin's linkage between them have been done in three dimensions. For many years we have known that there is abundant elastin in the mammalian lungs, which may be associated with etiology of... | ['Animals', 'Blood Vessels', 'Corrosion Casting', 'Dogs', 'Elastin', 'Lung', 'Microscopy, Electron, Scanning', 'Pulmonary Alveoli', 'Rabbits', 'Swine'] | 7,871,852 | [['B01.050'], ['A07.015'], ['E01.370.225.500.620.620.150', 'E01.370.225.750.600.620.150', 'E05.200.500.620.620.150', 'E05.200.750.600.620.150'], ['B01.050.150.900.649.313.750.250.216.200'], ['D05.750.078.421', 'D12.776.860.300.350'], ['A04.411'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['A04.411.715'], ['B01.05... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pathways Governing Polyethylenimine Polyplex Transfection in Microporous Annealed Particle Scaffolds. | Gene delivery using injectable hydrogels can serve as a potential method for regulated tissue regeneration in wound healing. Our microporous annealed particle (MAP) hydrogel has been shown to promote cellular infiltration in both skin and brain wounds, while reducing inflammation. Although the scaffold itself can promo... | ['Cell Line', 'Endocytosis', 'Fibroblasts', 'Humans', 'Hydrogels', 'Plasmids', 'Polyethyleneimine', 'Porosity', 'Tissue Scaffolds', 'Transfection'] | 30,513,197 | [['A11.251.210'], ['G04.417'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.280.320.375', 'D26.255.165.320.375'], ['G05.360.600'], ['D02.455.326.271.665.550.600', 'D02.491.650', 'D05.750.716.507.600', 'D25.720.716.507.600', 'J01.637.051.720.716.507.600'], ['G01.374.710'], ['E07.206.627', 'E07... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Detection of polyamines by a new enzymatic differential assay. (4). Fundamental study on a new enzymatic differential assay of blood]. | The enzymatic method for isolation and determination of urinary polyamines was modified to measure the polyamines in the blood. High recovery rates of polyamine in blood by enzymatic hydrolyzation were obtained, namely, 101.9 +/- 4.4% for diamine, 96.0 +/- 5.4% for spermidine and 104.1 +/- 3.3% for spermine. Furthermor... | ['Chromatography, High Pressure Liquid', 'Diamines', 'Humans', 'Methods', 'Oxidoreductases Acting on CH-NH Group Donors', 'Polyamines', 'Spermidine', 'Spermine'] | 3,776,770 | [['E05.196.181.400.300'], ['D02.092.782.258'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['D08.811.682.662'], ['D02.092.782'], ['D02.092.211.415.701.801', 'D02.092.782.677'], ['D02.092.211.415.701.801.821', 'D02.092.782.802']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of citalopram and escitalopram together with their active main metabolites desmethyl(es-)citalopram in human serum by column-switching high performance liquid chromatography (HPLC) and spectrophotometric detection. | We established a method for automated quantitative analysis of (es-)citalopram and desmethyl(es-)citalopram in serum using column-switching high performance liquid chromatography (HPLC). For sample clean-up serum was injected onto a LiChrospher CN 20 microm precolumn using 8% acetonitrile in deionized water. Drugs were... | ['Chromatography, High Pressure Liquid', 'Citalopram', 'Humans', 'Reproducibility of Results', 'Spectrophotometry, Ultraviolet', 'Stereoisomerism'] | 17,112,793 | [['E05.196.181.400.300'], ['D02.092.831.170', 'D02.626.320', 'D03.633.100.127.187'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['G02.607.445.682']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Rapid identification of Enterococcus hirae and Enterococcus durans by PCR and detection of a homologue of the E. hirae mur-2 Gene in E. durans. | During an evaluation of PCR for identification of isolates of Enterococcus hirae, a homologue with 82% identity to E. hirae mur-2 was identified in Enterococcus durans and was named mur-2(ed). PCR using primers for two genes (copY and murG) of E. hirae strains showed amplification with E. hirae strains only. PCR (under... | ['Bacterial Outer Membrane Proteins', 'Bacterial Typing Techniques', 'DNA, Bacterial', 'Enterococcus', 'Genes, Bacterial', 'N-Acetylglucosaminyltransferases', 'Polymerase Chain Reaction'] | 16,597,896 | [['D12.776.097.120', 'D12.776.543.100'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['D13.444.308.212'], ['B03.353.750.250.250', 'B03.510.550.250.250'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['D08.811.913.400.100.250'], ['E05.393.620.500']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Are Skin Fiducials Comparable to Bone Fiducials for Registration When Planning Navigation-assisted Musculoskeletal Tumor Resections in a Cadaveric Simulated Tumor Model? | BACKGROUND: To improve and achieve adequate bony surgical margins, surgeons may consider computer-aided navigation a promising intraoperative tool, currently applied to a relatively few number of patients in whom freehand resections might be challenging. Placing fiducials (markers) in the bone, identifying specific ana... | ['Bone Neoplasms', 'Cadaver', 'Fiducial Markers', 'Humans', 'Imaging, Three-Dimensional', 'Margins of Excision', 'Osteotomy', 'Pilot Projects', 'Skin', 'Surgery, Computer-Assisted', 'Tomography, X-Ray Computed'] | 31,764,337 | [['C04.588.149', 'C05.116.231'], ['C23.550.260.224'], ['E05.978.808.249', 'E07.695.237', 'E07.710.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['A10.830', 'C23.149.625'], ['E04.555.580'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'],... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Kindling as a model of temporal lobe epilepsy induces bilateral changes in spontaneous striatal activity. | Basal ganglia are engaged in seizure propagation, control of seizures, and in epilepsy-induced neuroplasticity. Here, we tested the hypothesis that previously observed histological and neurochemical changes in the striatum of amygdala-kindled rats as a model of temporal lobe epilepsy are reflected in alterations of spo... | ['Action Potentials', 'Amygdala', 'Animals', 'Corpus Striatum', 'Disease Models, Animal', 'Epilepsy, Temporal Lobe', 'Female', 'Functional Laterality', 'Kindling, Neurologic', 'Nerve Net', 'Neural Inhibition', 'Neural Pathways', 'Neuronal Plasticity', 'Neurons', 'Rats', 'Rats, Wistar', 'Substantia Nigra', 'Synaptic Tra... | 20,005,953 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['B01.050'], ['A08.186.211.200.885.287.249.487'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.228.140.490.360.290', 'C10.228.140.490.493.375'], ['F02.830.297.425', 'G11.561.225.425'], ['G11.561.4... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modeling the aminogenic potential of Enterococcus faecalis EF37 in dry fermented sausages through chemical and molecular approaches. | Amino acid decarboxylase activity of the Enterococcus faecalis strain EF37 was monitored during fermentation and ripening of a traditional dry fermented sausage from Northern Italy (Salame Veronese) by means of microbiological, chemical, and molecular approaches in relation to three technological factors: fermentation ... | ['Anti-Bacterial Agents', 'Bacterial Proteins', 'Colony Count, Microbial', 'DNA, Bacterial', 'Enterococcus faecalis', 'Fermentation', 'Glucose', 'Italy', 'Meat Products', 'Phenethylamines', 'Polymerase Chain Reaction', 'RNA, Messenger', 'Sodium Chloride', 'Temperature', 'Tyramine', 'Tyrosine Decarboxylase'] | 18,296,537 | [['D27.505.954.122.085'], ['D12.776.097'], ['E01.370.225.875.220', 'E05.200.875.220'], ['D13.444.308.212'], ['B03.353.750.250.250.280', 'B03.510.550.250.250.280'], ['G02.111.158.249', 'G03.191.249'], ['D09.947.875.359.448'], ['Z01.542.489'], ['G07.203.300.600.500', 'J02.500.600.500'], ['D02.092.471.683'], ['E05.393.620... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
The effects of daily injections of L-dihydroxyphenylalanine and 5-hydroxytryptophan in different temporal relationships on thyroid-gonadal interaction in an Indian finch, spotted munia, Lonchura punctulata. | Daily injection of L-dihydroxyphenylalanine (L-DOPA, a dopamine precursor) given 12 hr after 5-hydroxytryptophan (5-HTP, a serotonin precursor) stimulated testicular growth and body weight increase in the spotted munia Lonchura punctulata. Daily injections of the same drugs given 8 hr apart had the opposite effect, inh... | ['5-Hydroxytryptophan', 'Animals', 'Birds', 'Body Weight', 'Female', 'Levodopa', 'Light', 'Male', 'Sexual Behavior, Animal', 'Testis', 'Thyroid Gland', 'Thyroidectomy', 'Thyroxine'] | 1,397,999 | [['D12.125.072.050.850.479'], ['B01.050'], ['B01.050.150.900.248'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D02.092.311.200.480', 'D02.455.426.559.389.657.166.175.200.480', 'D12.125.072.050.685.400.500', 'D12.125.072.050.875.130.500'], ['G01... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Health research systems: promoting health equity or economic competitiveness? | International collaborative health research is justifiably expected to help reduce global health inequities. Investment in health policy and systems research in developing countries is essential to this process but, currently, funding for international research is mainly channelled towards the development of new medica... | ['Competitive Behavior', 'Global Health', 'Health Policy', 'Health Promotion', 'Health Services Research', 'Health Status Disparities', 'Humans', 'International Cooperation', 'Internationality', 'Private Sector', 'Public Health', 'Public Sector', 'Technology Transfer'] | 22,271,965 | [['F01.145.813.105'], ['H02.403.371', 'N01.400.337'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['I02.233.332.445', 'N02.421.726.407.579'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['B01.050.150.900.649.313.988... | ['Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 |
How hydrophobic drying forces impact the kinetics of molecular recognition. | A model of protein-ligand binding kinetics, in which slow solvent dynamics results from hydrophobic drying transitions, is investigated. Molecular dynamics simulations show that solvent in the receptor pocket can fluctuate between wet and dry states with lifetimes in each state that are long enough for the extraction o... | ['Hydrophobic and Hydrophilic Interactions', 'Kinetics', 'Ligands', 'Models, Chemical', 'Molecular Dynamics Simulation', 'Protein Binding', 'Water'] | 23,901,110 | [['G02.409'], ['G01.374.661', 'G02.111.490'], ['D27.720.470.480'], ['E05.599.495'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G02.111.679', 'G03.808'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Laparoscopic management of malignant ovarian cysts: a 78-case national survey. Part 2: Follow-up and final treatment. | This paper reports a retrospective multi-institutional French survey carried out in 1992 to determine the incidence of laparoscopic management of malignant ovarian cysts. Of 5307 ovarian lesions treated endoscopically, 78 were malignant (1.47%) including 60 borderline tumours (77%) and 18 ovarian cancers (23%). Laparos... | ['Female', 'France', 'Health Surveys', 'Humans', 'Laparoscopy', 'Laparotomy', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Ovarian Cysts', 'Ovarian Neoplasms', 'Retrospective Studies'] | 7,556,836 | [['Z01.542.286'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E04.406'], ['C04.697.655', 'C23.550.727.655'], ['E01.789.625'], ['C04.182.612', 'C13.351.500.056.630.580', 'C19.391.630.580'], [... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Fluorometric determination of "albumin-titratable bilirubin" in the jaundiced neonate. | We report a fluorometric technique for determination of albumin-titratable bilirubin in the jaundiced neonate. Although bilirubin alone has very little native fluorescence, considerable emission is observed in the presence of albumin under acid conditions. Analysis of the plasma sample alone and in the presence of exce... | ['Bilirubin', 'Female', 'Fetal Blood', 'Humans', 'Infant, Newborn', 'Jaundice, Neonatal', 'Kinetics', 'Pregnancy', 'Protein Binding', 'Serum Albumin'] | 1,164,793 | [['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614.451.500', 'C23.550.429.249.500'], ['G01.374.661', 'G02.111.490'], ['G08.686.784.769'],... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Hyperuricemia is associated with the development of the composite outcomes of new cardiovascular events and chronic allograft nephropathy. | BACKGROUND: To investigate the prevalence and the predictors for the development of hyperuricemia at 6 months after kidney transplantation, and its association with clinical outcomes including patient and graft survival, the development of new cardiovascular events and chronic allograft nephropathy (CAN).MATERIALS AND ... | ['Adult', 'Aged', 'Biopsy', 'Cardiovascular Diseases', 'Female', 'Graft Survival', 'Humans', 'Hyperuricemia', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Odds Ratio', 'Patient Selection', 'Postoperative Complications', 'Retrospective Studies', 'Time Factors', 'Transplantation, Homologous'] | 18,791,445 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C14'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.449'], ['E02.870.500', 'E04.936.450.485', 'E04.95... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Copper-64 Labeled PEGylated Exosomes for In Vivo Positron Emission Tomography and Enhanced Tumor Retention. | Exosomes have attracted tremendous attention due to their important role in physiology, pathology, and oncology, as well as promising potential in biomedical applications. Although great efforts have been dedicated to investigating their biological properties and applications as natural cancer drug-delivery systems, th... | ['Animals', 'Cell Line, Tumor', 'Copper Radioisotopes', 'Exosomes', 'Mice', 'Polyethylene Glycols', 'Positron-Emission Tomography', 'Tissue Distribution'] | 31,560,538 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['D01.496.749.270'], ['A11.284.295.588.750', 'A11.284.430.214.190.875.190.880.495'], ['B01.050.150.900.649.313.992.635.505.500'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399',... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Gammaherpesvirus persistence alters key CD8 T-cell memory characteristics and enhances antiviral protection. | In herpesvirus infections, the virus persists for life but is contained through T-cell-mediated immune surveillance. How this immune surveillance operates is poorly understood. Recent studies of other persistent infections have indicated that virus persistence is associated with functional deficits in the CD8(+) T-cell... | ['Animals', 'CD8-Positive T-Lymphocytes', 'Gammaherpesvirinae', 'Herpesviridae Infections', 'Immunologic Memory', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Virus Latency'] | 16,912,282 | [['B01.050'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['B04.280.210.400', 'B04.280.382.400', 'B04.613.204.500'], ['C01.925.256.466'], ['G12.450.050.500'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['B01.050... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Local variation in the tearing strength of chemically modified pericardium. | Forty squares of tissue, 40 mm X 40 mm, were harvested from bovine pericardium fixed in glutaraldehyde free of tension. Two parallel dumb-bell specimens were excised from each square. In 20 pairs of adjacent samples, two 1 mm cuts were introduced into one of the samples at the centre of the dumb-bell. The other 20 pair... | ['Animals', 'Bioprosthesis', 'Cattle', 'Elasticity', 'Heart Valve Prosthesis', 'In Vitro Techniques', 'Materials Testing', 'Pericardium', 'Tensile Strength'] | 2,742,950 | [['B01.050'], ['E07.695.100'], ['B01.050.150.900.649.313.500.380.271'], ['G01.374.590'], ['E07.695.310'], ['E05.481'], ['E05.570'], ['A07.541.795', 'A10.615.789.470'], ['G01.374.850']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: modulation of spontaneous 60-kDa heat shock protein autoimmunity. | Nonobese diabetic (NOD) mice develop insulitis and diabetes through a process involving autoimmunity to the 60-kDa heat shock protein (HSP60). Treatment of NOD mice with HSP60 or with peptides derived from HSP60 inhibits this diabetogenic process. We now report that NOD diabetes can be inhibited by vaccination with a D... | ['Adjuvants, Immunologic', 'Amino Acid Sequence', 'Animals', 'Autoantibodies', 'Autoantigens', 'Chaperonin 60', 'CpG Islands', 'Diabetes Mellitus, Type 1', 'Female', 'Growth Inhibitors', 'Heat-Shock Proteins', 'Humans', 'Hypoglycemic Agents', 'Immunization Schedule', 'Immunoglobulin G', 'Immunoglobulin Isotypes', 'Immu... | 11,086,048 | [['D27.505.696.477.067'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D23.050.422'], ['D08.811.277.040.025.142.500.500', 'D12.776.580.216.210.590.750'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.3... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Chemotherapy Immunophenoprofiles in Non-Small-Cell Lung Cancer by Personalized Membrane Proteomics. | OBJECTIVES: No study has addressed how the immune status at the molecular level is affected by first-line pemetrexed and cisplatin (PEM-CIS) combination therapy in patients with non-small-cell lung cancer (NSCLC). Thus, we aimed to identify the immune status from membrane proteome alterations in patients with NSCLC upo... | ['Aged', 'Carcinoma, Non-Small-Cell Lung', 'Cell Membrane', 'Female', 'Humans', 'Leukocytes, Mononuclear', 'Lung Neoplasms', 'Male', 'Membrane Proteins', 'Middle Aged', 'Phenotype', 'Proteomics'] | 29,278,294 | [['M01.060.116.100'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['A11.284.149'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.490.555'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['D12.776.543'], ['M01.060.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
GATA1 Expression in BCR/ABL1-negative Myeloproliferative Neoplasms. | BACKGROUND: This study aimed to determine GATA1 expression levels to better characterize subgroups in BCR/ABL1-negative myeloproliferative neoplasms (MPNs).METHODS: This study enrolled 49 patients diagnosed as having BCR/ABL1-negative MPN on the basis of the 2016 World Health Organization classification : nine polycyth... | ['Alleles', 'Bone Marrow', 'Cytogenetic Analysis', 'Fusion Proteins, bcr-abl', 'GATA1 Transcription Factor', 'Gene Expression', 'Humans', 'Immunohistochemistry', 'Janus Kinase 2', 'Myeloproliferative Disorders', 'Polymorphism, Single Nucleotide', 'Primary Myelofibrosis', 'Severity of Illness Index', 'Thrombocythemia, E... | 29,611,379 | [['G05.360.340.024.340.030'], ['A15.382.216'], ['E01.370.225.500.385', 'E05.200.500.385', 'E05.242.385', 'E05.393.285'], ['D08.811.913.696.620.682.725.500.500', 'D12.776.602.500.500.100', 'D12.776.624.664.500.100', 'D12.776.624.664.700.171.500'], ['D12.776.260.235.500', 'D12.776.260.257.100', 'D12.776.930.216.500', 'D1... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Expression of apoptosis-related genes in chronic cyclosporine nephrotoxicity in mice. | To define the mechanism of cyclosporine (CsA)-induced apoptosis, we investigated the expression of apoptosis-related genes in experimental chronic CsA nephrotoxicity. Mice on a low-salt (0.01%) diet were given vehicle (VH, olive oil, 1 mg/kg/day), or CsA (30 mg/kg/day), and sacrificed at 1 and 4 weeks. Apoptosis was de... | ['Animals', 'Apoptosis', 'Blood Pressure', 'Body Weight', 'Caspase 1', 'Caspase 3', 'Caspases', 'Chronic Disease', 'Cyclosporine', 'Fas Ligand Protein', 'Immunohistochemistry', 'Immunosuppressive Agents', 'Kidney Diseases', 'Male', 'Membrane Glycoproteins', 'Mice', 'Mice, Inbred ICR', 'Proto-Oncogene Proteins', 'Proto-... | 12,123,203 | [['B01.050'], ['G04.146.954.035'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D08.811.277.656.262.500.126.550.100', 'D08.811.277.656.300.200.126.550.100', 'D12.644.360.075.405.550.100', 'D12.776.476.0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A community level syphilis prevention programme: outcome data from a controlled trial. | OBJECTIVES: This study investigated the impact of a small media campaign to reduce syphilis through testing, treatment, and condom use in two urban predominantly African-American communities with high syphilis rates.METHODS: Data were collected from intervention and comparison zip codes using cross sectional street int... | ['African Americans', 'Condoms', 'Cross-Sectional Studies', 'Female', 'Health Promotion', 'Humans', 'Male', 'Mass Media', 'Poverty Areas', 'Sexual Behavior', 'Syphilis', 'Texas', 'Treatment Outcome', 'Urban Health'] | 15,054,168 | [['M01.686.508.100.100', 'M01.686.754.100'], ['E07.190.270.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.590'], ['I01.880.853.996.535.550', 'N01.824.600.550'], ['F01.145.802'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
The dendroanalysis of oak trees as a method of biomonitoring past and recent contamination in an area influenced by uranium mining. | We reconstructed the contamination history of an area influenced by 40 years of uranium mining and subsequent remediation actions using dendroanalysis (i.e., the determination of the elemental content of tree rings). The uranium content in the tree rings of four individual oak trees (Quercus sp.) was determined by lase... | ['Environmental Monitoring', 'Environmental Restoration and Remediation', 'Mining', 'Quercus', 'Soil Pollutants', 'Uranium'] | 26,104,903 | [['N06.850.460.350.080', 'N06.850.780.375'], ['N06.230.080.600', 'N06.850.460.375'], ['J01.576.655.875.500'], ['B01.650.940.800.575.912.250.859.750.300.500'], ['D27.888.284.756'], ['D01.268.271.100.950', 'D01.268.556.900', 'D01.496.749.305.100.950', 'D01.552.020.940', 'D01.552.544.900']] | ['Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
A simple model for learning stereotactic skills in ultrasound-guided amniocentesis. | BACKGROUND: Amniocentesis is an important procedure for antenatal diagnosis but requires stereotactic skill acquisition that may be facilitated by the use of a model.TECHNIQUE: A model using a gelatin mold with "targets" within is created. The model is used to facilitate development of stereotactic skills and to demons... | ['Amniocentesis', 'Gynecology', 'Models, Biological', 'Obstetrics', 'Ultrasonography, Prenatal'] | 9,699,771 | [['E01.370.225.500.384.050', 'E01.370.225.998.329.309', 'E01.370.378.630.050', 'E04.665.600.309', 'E05.200.500.384.050', 'E05.200.998.329.309', 'E05.242.384.050'], ['H02.403.763.750', 'H02.403.810.310'], ['E05.599.395'], ['H02.403.810.450'], ['E01.370.350.850.865', 'E01.370.378.630.865']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Market research surveys in the marketing of consumer products. | To achieve commercial success, any skin care product having given functional properties will on the consumer market also depend on a high degree of attraction, comfort and effective marketing. To accomplish this, consumer surveys are necessary in the various stages of product development and the marketing process. A br... | ['Adult', 'Aged', 'Commerce', 'Consumer Product Safety', 'Data Collection', 'Dermatologic Agents', 'Economic Competition', 'Emollients', 'Female', 'Humans', 'Middle Aged', 'Skin Diseases'] | 1,466,186 | [['M01.060.116'], ['M01.060.116.100'], ['J01.219'], ['N06.850.210'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['D27.505.954.444'], ['N03.219.188'], ['D27.505.954.444.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C17.800']] | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Improved cardiac performance through pacing-induced diaphragmatic stimulation: a novel electrophysiological approach in heart failure management? | AIMS: Pharmacological conditioning of the phrenic nerve can positively influence systolic performance, and diaphragm activation improves ventilatory function. Here we investigate whether pacing-induced diaphragmatic stimulation (PIDS) may improve left ventricular (LV) systolic function.METHODS AND RESULTS: We studied a... | ['Aged', 'Cardiac Pacing, Artificial', 'Diaphragm', 'Electrodes', 'Electrophysiologic Techniques, Cardiac', 'Female', 'Heart Failure, Systolic', 'Hemodynamics', 'Humans', 'Kinetocardiography', 'Male', 'Middle Aged', 'Treatment Outcome', 'Ventricular Dysfunction, Left'] | 19,168,496 | [['M01.060.116.100'], ['E02.331.200'], ['A02.633.567.900.300'], ['E07.305.250'], ['E01.370.370.380.245', 'E01.370.405.267'], ['C14.280.434.676'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.370.380.450'], ['M01.060.116.630'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.80... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
ALK-1 mutations in liver transplanted patients with hereditary hemorrhagic telangiectasia. | Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominantly inherited disorder characterized by cutaneous and mucosal telangiectasias, epistaxis and arteriovenous malformations in lung, liver, central nervous system, and gastrointestinal tract. Mutations in the genes for endoglin (ENG) and for activin A rec... | ['Activin Receptors, Type I', 'Activin Receptors, Type II', 'Adult', 'Antigens, CD', 'Endoglin', 'Female', 'Humans', 'Liver Transplantation', 'Male', 'Middle Aged', 'Mutation', 'Pedigree', 'Prognosis', 'Receptors, Cell Surface', 'Telangiectasia, Hereditary Hemorrhagic', 'Vascular Cell Adhesion Molecule-1'] | 16,123,970 | [['D08.811.913.696.620.682.700.062.500', 'D12.776.543.750.750.400.820.500.500'], ['D08.811.913.696.620.682.700.062.750', 'D12.776.543.750.750.400.820.500.750'], ['M01.060.116'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D12.776.543.750.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.147.725.490', ... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Treatment of recurrent peripheral nerve entrapment problems: role of scar formation and its possible treatment. | Surgical management of peripheral nerve entrapment syndromes is usually successful, but the recurrence of symptoms after initial improvement can and does occur. Extraneural fibrosis is one possible cause of recurrent peripheral nerve problems as a result of nerve compression or tethering. Several approaches to prevent ... | ['Animals', 'Carbohydrates', 'Cicatrix', 'Decompression, Surgical', 'Humans', 'Nerve Compression Syndromes', 'Polymers', 'Postoperative Complications', 'Rats', 'Recurrence', 'Reoperation'] | 11,525,211 | [['B01.050'], ['D09'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['E04.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.668.829.550'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['C23.550.767'], ['B01.050.150.900.649.313.992.635.505.700'], ['C23.550.291.937'], ['E04.690']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Diabetic Myonecrosis: A Rare Complication of Diabetes Mellitus Mimicking Deep Vein Thrombosis. | BACKGROUND Diabetic myonecrosis is an uncommon complication of long-standing poorly controlled diabetes mellitus. It presents as acute non-traumatic swelling and pain of the lower extremity, which can mimic deep vein thrombosis (DVT). The clinical course is usually self-limiting and patients respond well to supportive ... | ['Anti-Inflammatory Agents, Non-Steroidal', 'Biomarkers', 'Blood Glucose', 'Diabetes Mellitus, Type 2', 'Drug Therapy, Combination', 'Humans', 'Leg', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Necrosis', 'Platelet Aggregation Inhibitors', 'Predictive Value of Tests', 'Risk Factors', 'Sens... | 28,074,044 | [['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D23.101'], ['D09.947.875.359.448.500'], ['C18.452.394.750.149', 'C19.246.300'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['A02.633.567', 'A10.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Perturbation of the growth kinetics of C3H mouse mammary carcinoma by irradiation of tumour and host and by attempted pre-immunization of host. | The kinetics of development and subsequent growth of a C3H mouse mammary tumour after implantation of 10(6) cells was quantified by observation and statistical analysis of latent period and growth rate for different categories of tumour. These comprised control tumours, tumours recurring after large single doses of X-r... | ['Adenocarcinoma', 'Animals', 'Dose-Response Relationship, Radiation', 'Immunization', 'Mammary Neoplasms, Experimental', 'Mice', 'Misonidazole', 'Neoplasm Recurrence, Local', 'Neoplasm Transplantation', 'Time Factors', 'Transplantation, Homologous'] | 7,387,855 | [['C04.557.470.200.025'], ['B01.050'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['B01.050... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Knock-down of PQBP1 impairs anxiety-related cognition in mouse. | PQBP1 (polyglutamine tract-binding protein 1) is a causative gene for a relatively frequent X-linked syndromic and non-syndromic mental retardation (MR). To analyze behavioral abnormalities of these patients from molecular basis, we developed a knock-down (KD) mouse model. The KD mice possess a transgene expressing 498... | ['Animals', 'Anxiety', 'Carrier Proteins', 'Cognition', 'DNA-Binding Proteins', 'Disease Models, Animal', 'Female', 'Gene Expression', 'Gene Knockdown Techniques', 'Humans', 'Male', 'Maze Learning', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Nuclear Proteins'] | 19,661,183 | [['B01.050'], ['F01.470.132'], ['D12.776.157'], ['F02.463.188'], ['D12.776.260'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.297'], ['E05.393.335.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.874.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.0... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nitrogen removal and N2 | Nitrogen removal, N2O emission and nitrogen removal functional gene abundances in intermittent aerated (IA) and non-aerated (NA) subsurface wastewater infiltration systems (SWISs) under different organic loading rates (OLRs) were investigated. Aeration successfully created aerobic condition at 50cm depth and did not ch... | ['Biological Oxygen Demand Analysis', 'Denitrification', 'Nitrogen', 'Waste Water'] | 28,777,994 | [['N06.850.460.350.080.500', 'N06.850.780.375.349'], ['G02.111.587.250', 'G02.607.560.250', 'G16.500.768.249'], ['D01.268.604', 'D01.362.625'], ['D20.944.932', 'N06.850.460.710.865']] | ['Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Study of booster doses of two Haemophilus influenzae type b conjugate vaccines including their interchangeability. | A prospective, two center study of 319 children was undertaken to assess responses to booster immunization in healthy 18-month-olds who completed primary immunization 12 months earlier with Haemophilus influenzae type b (Hib) conjugate vaccine (either HbOC or PRP-T). Interchangeability of these products as boosters was... | ['Antibodies', 'Bacterial Proteins', 'Erythema', 'Female', 'Haemophilus Infections', 'Haemophilus Vaccines', 'Humans', 'Immunoglobulin G', 'Infant', 'Male', 'Prospective Studies', 'Tetanus Toxoid', 'Vaccines, Conjugate', 'Vaccines, Synthetic'] | 8,994,313 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.097'], ['C17.800.229', 'C23.888.885.328'], ['C01.150.252.400.700.433'], ['D20.215.894.135.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of influenza A (H7N9) viruses isolated from human cases imported into Taiwan. | A novel avian influenza A (H7N9) virus causes severe human infections and was first identified in March 2013 in China. The H7N9 virus has exhibited two epidemiological peaks of infection, occurring in week 15 of 2013 and week 5 of 2014. Taiwan, which is geographically adjacent to China, faces a large risk of being affe... | ['Evolution, Molecular', 'Female', 'Humans', 'Influenza A Virus, H7N9 Subtype', 'Influenza, Human', 'Male', 'Taiwan'] | 25,748,033 | [['G05.045.250', 'G16.075.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400.800'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['Z01.252.474.872', 'Z01.639.850']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
[The naloxone test in patients with varicocele]. | AIM: Is there any influence of naloxone administration on plasma levels of hypophyseal and gonadal hormones in varicocele patients?MATERIAL AND METHODS: The naloxone test (0.4 mg i.v.) was performed in 15 varicocele patients The plasma FSH, LH, prolactin, testosterone and estradiol levels were determined before and 30,... | ['Adult', 'Estradiol', 'Follicle Stimulating Hormone', 'Humans', 'Luteinizing Hormone', 'Male', 'Naloxone', 'Narcotic Antagonists', 'Prolactin', 'Retrospective Studies', 'Testosterone', 'Varicocele'] | 9,695,347 | [['M01.060.116'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.343.463', 'D12.644.548.691.525.343.463'], ['D03.132.577.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Concurrent lung cancer in non-tuberculous mycobacteriosis: case report. | An 82-year-old woman was admitted to our hospital after multiple round opacities were detected in chest X-rays performed during a routine health screening. Mycobacterium avium complex (MAC) was found in sputum cultures, and compatible pathological findings on biopsy confirmed pulmonary MAC infection, whereas biopsies f... | ['Adenocarcinoma', 'Adenocarcinoma of Lung', 'Aged, 80 and over', 'Female', 'Humans', 'Lung', 'Lung Neoplasms', 'Mycobacterium avium Complex', 'Mycobacterium avium-intracellulare Infection', 'Tomography, X-Ray Computed'] | 22,531,123 | [['C04.557.470.200.025'], ['C04.557.470.200.025.022', 'C04.588.894.797.520.055'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['B03.510.024.962.500.720.100', 'B03.510.460.400.410.552.552.720.100'], ['C01.150.252.410.040.55... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Filled and glycosylated carbon nanotubes for in vivo radioemitter localization and imaging. | Functionalization of nanomaterials for precise biomedical function is an emerging trend in nanotechnology. Carbon nanotubes are attractive as multifunctional carrier systems because payload can be encapsulated in internal space whilst outer surfaces can be chemically modified. Yet, despite potential as drug delivery sy... | ['Acetylglucosamine', 'Carbohydrate Metabolism', 'Glycosylation', 'Humans', 'Isotope Labeling', 'Microscopy, Electron, Scanning Transmission', 'Nanotechnology', 'Nanotubes, Carbon', 'Oxidation-Reduction', 'Radioisotopes', 'Stomach', 'Thyroid Gland', 'Tissue Distribution', 'Tomography, X-Ray Computed'] | 20,473,287 | [['D09.067.342.531.050'], ['G02.111.158', 'G03.191'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.522'], ['E01.370.350.515.402.580.480', 'E05.595.402.580.480'], ['H01.603', 'J01.897.520.600'], ['D01.268.150.250.500', 'J01.637.512.850.500'], ['G02.700', 'G03.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Genetic variation in PRL and PRLR, and relationships with serum prolactin levels and breast cancer risk: results from a population-based case-control study in Poland. | INTRODUCTION: Studies suggest that high circulating levels of prolactin increase breast cancer risk. It is unclear if genetic variations in prolactin (PRL) or prolactin receptor (PRLR) genes also play a role. Thus, we examined the relationship between single nucleotide polymorphisms (SNPs) in PRL and PRLR, serum prolac... | ['Adult', 'Aged', 'Breast Neoplasms', 'Case-Control Studies', 'Female', 'Genotype', 'Humans', 'Middle Aged', 'Poland', 'Polymorphism, Single Nucleotide', 'Postmenopause', 'Premenopause', 'Prolactin', 'Receptors, Prolactin', 'Risk Factors'] | 21,470,416 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.542.248.679'], ['G05.365.795.598'], ['G08.686.157.500.625', 'G08.686.841.249.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Use of maximal expiratory flow-volume curves with air and helium-oxygen in the detection of ventilatory abnormalities in population surveys. | Flow-volume curves with air and helium, and spirometry were obtained in 423 subjects during epidemiologic health surveys; subjects were divided into 4 groups: nonsmokers and smokers not exposed to air pollutants at work, and nonsmoking and smoking grain elevator workers. The data obtained from 78 healthy nonsmokers who... | ['Air Pollutants, Occupational', 'Forced Expiratory Flow Rates', 'Health Surveys', 'Helium', 'Humans', 'Male', 'Maximal Expiratory Flow-Volume Curves', 'Oxygen', 'Respiration Disorders', 'Smoking', 'Spirometry'] | 7,235,364 | [['D27.888.284.101.268'], ['E01.370.386.700.660.225', 'G09.772.650.300'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['D01.268.613.350', 'D01.362.641.352'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.700.660.225.505', 'G09.772.650.300.630'], ['D01.268.185.550', 'D... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence. | Fluid shear stress promotes the emergence of hematopoietic stem cells (HSCs) in the aorta-gonad-mesonephros (AGM) of the developing mouse embryo. We determined that the AGM is enriched for expression of targets of protein kinase A (PKA)-cAMP response element-binding protein (CREB), a pathway activated by fluid shear st... | ['Animals', 'Bone Morphogenetic Proteins', 'Cyclic AMP Response Element-Binding Protein', 'Cyclic AMP-Dependent Protein Kinases', 'Embryo, Mammalian', 'Endothelial Cells', 'Hematopoietic Stem Cells', 'Mesonephros', 'Mice', 'Mice, Mutant Strains', 'Signal Transduction', 'Sodium-Calcium Exchanger'] | 25,870,201 | [['B01.050'], ['D12.644.276.954.200', 'D12.776.467.942.200', 'D23.529.942.200'], ['D12.776.260.108.184', 'D12.776.930.127.184'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['A16.254'], ['A11.436.275'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['A16.599'], ['B01.050.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Twenty-one-gene recurrence score assay in BRCA-associated versus sporadic breast cancers: Differences based on germline mutation status. | BACKGROUND: Biological differences between BRCA-associated breast cancer and sporadic breast cancer may warrant different adjuvant chemotherapy (ACRx) recommendations despite similar phenotypic features. A 21-gene expression profile (Oncotype DX) generates a prognostic recurrence score (RS) that predicts the ACRx benef... | ['Adult', 'Aged', 'Breast Neoplasms', 'Cohort Studies', 'Databases, Factual', 'Disease-Free Survival', 'Female', 'Gene Expression Profiling', 'Genes, BRCA1', 'Genes, BRCA2', 'Genetic Predisposition to Disease', 'Germ-Line Mutation', 'Humans', 'Logistic Models', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Recurren... | 26,859,126 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Comparison of Bloodmeal Digestion and the Peritrophic Matrix in Four Sand Fly Species Differing in Susceptibility to Leishmania donovani. | The early stage of Leishmania development in sand flies is closely connected with bloodmeal digestion. Here we compared various parameters of bloodmeal digestion in sand flies that are either susceptible (Phlebotomus argentipes and P. orientalis) or refractory (P. papatasi and Sergentomyia schwetzi) to Leishmania donov... | ['Animals', 'Blood', 'Digestion', 'Disease Susceptibility', 'Eating', 'Feces', 'Female', 'Insect Vectors', 'Leishmania donovani', 'Leishmaniasis, Visceral', 'Membranes', 'Proteolysis', 'Psychodidae', 'Species Specificity'] | 26,030,610 | [['B01.050'], ['A12.207.152', 'A15.145'], ['G07.203.650.250', 'G10.261.190'], ['C23.550.291.687', 'G07.100.250'], ['G07.203.650.283', 'G10.261.330'], ['A12.459'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['B01.268.475.868.488.230'], ['C01.610.752.300.500.510', 'C01.920.813.510'], ['A10.615'], ['G02.1... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The effects of cerebral sensory and motor cortical lesions on conditioned tactile placing in cats with pyramid section. | Cats after unilateral bulbar pyramid section showed permanent loss of tactile placing in the contralateral limbs. However, the cats could be trained to place the forelimb following light touch in a conditioning situation with food as a reward. Subsequent unilateral or bilateral cerebral cortical lesions involving senso... | ['Animals', 'Cats', 'Conditioning, Classical', 'Conditioning, Operant', 'Dominance, Cerebral', 'Locomotion', 'Motor Cortex', 'Posture', 'Pyramidal Tracts', 'Somatosensory Cortex', 'Touch'] | 6,880,871 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['F02.463.425.179.308'], ['F02.463.425.179.509'], ['F02.830.297', 'G11.561.225'], ['G07.568.500', 'G11.427.410.568'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['G11.427.695'], ['A08.186.854.300', 'A08.612.380.730'], ['... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Temporal variation and persistence of bacteria in streams. | Better understanding of bacterial fate and transport in watersheds is necessary for improved regulatory management of impaired streams. Novel statistical time series analyses of coliform data can be a useful tool for evaluating the dynamics of temporal variation and persistence of bacteria within a watershed. For this ... | ['Bacteria', 'Water Microbiology'] | 18,574,188 | [['B03'], ['H01.158.273.540.274.777', 'N06.850.425.450']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Moment analysis of near-equilibrium binding interactions during electrophoresis. | The electrophoretic transport of three chemically reacting species, two of which can bind reversibly to form the third, is analyzed mathematically. The species are assumed to move horizontally through a long channel with different electrophoretic mobilities and diffusion coefficients. By considering small perturbations... | ['Binding Sites', 'Biopolymers', 'Computer Simulation', 'Electrophoresis', 'Microfluidics', 'Models, Chemical'] | 18,233,702 | [['G02.111.570.120'], ['D05.750.078', 'D25.720.099', 'J01.637.051.720.099'], ['L01.224.160'], ['E05.196.401', 'E05.301.300'], ['E05.830.666', 'H01.671.808.500', 'J01.897.520.500.500'], ['E05.599.495']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Myomectomy during caesarean: a retrospective evaluation of 16 cases. | AIM: To evaluate the results and complications of myomectomy carried out during caesarean section.MATERIALS AND METHOD: A retrospective study of 16 patients who underwent myomectomy concurrently with caesarean section in our clinic between January 2009 and September 2012 was conducted. The pre- and postoperative haemog... | ['Adult', 'Cesarean Section', 'Female', 'Humans', 'Leiomyoma', 'Length of Stay', 'Postoperative Complications', 'Pregnancy', 'Retrospective Studies', 'Treatment Outcome', 'Uterine Myomectomy', 'Uterine Neoplasms'] | 24,013,433 | [['M01.060.116'], ['E04.520.252.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.590.450'], ['E02.760.400.480', 'N02.421.585.400.480'], ['C23.550.767'], ['G08.686.784.769'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Rare presentations of hyperthyroidism--Basedow's paraplegia and pancytopenia. | Typical presentations of hyperthyroidism are palpitation, nervousness, tremor, malaise, and weight loss. Hyperthyroidism affects nearly every system in the body, and some patients may manifest neurologic or hematologic symptoms. Atypical presentations of hyperthyroidism often pose a great challenge in diagnosis and tre... | ['Adrenergic beta-Antagonists', 'Adult', 'Antithyroid Agents', 'Female', 'Humans', 'Hyperthyroidism', 'Methimazole', 'Pancytopenia', 'Paraplegia', 'Propranolol'] | 19,371,562 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['D06.347.100', 'D27.505.696.399.450.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.397'], ['D02.886.489.600', 'D03.383.129.308.535'], ['C15.378.700'], ['C10.597.622.669', 'C23.888.592.636.637'], ['D02.033.100.624.698.7... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Eating and activity habits of overweight children on weekdays and weekends. | OBJECTIVE: To determine whether eating, sedentary, and physical activity behaviors differ on weekdays and weekends in a sample of children who are overweight and obese.METHODS: Eighty-one children aged 6-9 years old who were overweight or obese and enrolled in a weight management program completed three-day food diarie... | ['Child', 'Energy Intake', 'Exercise', 'Feeding Behavior', 'Female', 'Humans', 'Male', 'Overweight', 'Time Factors'] | 21,774,578 | [['M01.060.406'], ['G07.203.650.240.340'], ['G11.427.410.698.277', 'I03.350'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.144.699', 'E01.370.600.115.100.160.120.699', 'G07.100.100.160.120.699'], ['G01.910.857']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Sequence analysis of the 47-kilodalton major integral membrane immunogen of Treponema pallidum. | The complete primary amino acid sequence for the 47-kilodalton (kDa) major integral membrane immunogen of Treponema pallidum subsp. pallidum was obtained by using a combined strategy of DNA sequencing (of the cloned gene in Escherichia coli) and N-terminal amino acid sequencing of the native (T. pallidum subsp. pallidu... | ['Amino Acid Sequence', 'Antigens, Bacterial', 'Antigens, Surface', 'Bacterial Proteins', 'Base Sequence', 'Cloning, Molecular', 'DNA, Bacterial', 'Genes, Bacterial', 'Membrane Proteins', 'Molecular Sequence Data', 'Molecular Weight', 'Peptide Fragments', 'Treponema pallidum'] | 2,642,466 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D23.050.161'], ['D23.050.301'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308.212'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['D12.776.543'], ['L01.453.245.667'], ['... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Characteristics and prognosis of lone atrial fibrillation. 30-year follow-up in the Framingham Study. | In 30 years of follow-up of 5,209 participants in the Framingham Study, 193 men and 183 women developed atrial fibrillation (AF). Among this group, "lone" AF occurred in 32 men and 11 women free of coronary heart disease, congestive heart failure, rheumatic heart disease, and hypertensive cardiovascular disease. To det... | ['Adult', 'Aged', 'Atrial Fibrillation', 'Cerebrovascular Disorders', 'Cholesterol', 'Coronary Disease', 'Electrocardiography', 'Female', 'Follow-Up Studies', 'Heart Failure', 'Humans', 'Male', 'Middle Aged', 'Prognosis'] | 4,068,186 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.067.198', 'C23.550.073.198'], ['C10.228.140.300', 'C14.907.253'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.372.500.750.249', 'N05.715.360.330.5... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Changes of serum anti-thyroid antibodies during and after pregnancy in autoimmune thyroid diseases. | Changes of serum anti-thyroglobulin haemagglutination antibodies (TGHA) and anti-thyroid microsomal haemagglutination antibodies (MCHA) were observed during pregnancy and after delivery in Graves' disease and autoimmune thyroiditis. Both TGHA and MCHA decreased as pregnancy progressed, and sometimes they became negativ... | ['Abortion, Spontaneous', 'Adolescent', 'Adult', 'Antibodies', 'Autoimmune Diseases', 'Female', 'Hemagglutination Tests', 'Humans', 'Postpartum Period', 'Pregnancy', 'Pregnancy Complications', 'Thyroglobulin', 'Thyroid Diseases', 'Thyroid Gland', 'Time Factors'] | 639,347 | [['C13.703.039', 'G08.686.784.769.496.125'], ['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['C20.111'], ['E01.370.225.812.735.050.375', 'E05.200.812.735.050.375', 'E05.478.594.760.050.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Orosomucoid content of pleural and peritoneal effusions. | 22 nonneoplastic, noninflammatory effusions (cirrhosis and congestive heart failure), 12 non-neoplastic inflammatory effusions (tuberculosis, lupus erythematosus, rheumatoid arthritis, and idiopathic pleuropericarditis), and 58 neoplastic effusions (cancer of lung, breast, ovary, and pancreas, and lymphoma) were analyz... | ['Albumins', 'Ascitic Fluid', 'Carbohydrates', 'Chemical Phenomena', 'Chemistry', 'Chromatography, Gel', 'Electrophoresis, Polyacrylamide Gel', 'Globulins', 'Humans', 'Immunodiffusion', 'Neoplasms', 'Orosomucoid', 'Pleural Effusion'] | 4,209,434 | [['D12.776.034'], ['A12.207.119'], ['D09'], ['G02'], ['H01.181'], ['E05.196.181.400.250'], ['E05.196.401.402', 'E05.301.300.319'], ['D12.776.377'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.735.645.350', 'E05.200.812.735.645.350', 'E05.478.594.760.645.350', 'E05.478.605.492.350'], ['C04'], ['D1... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of in vitro fermentation techniques upon kinetics of fiber digestion. | Three in vitro fermentation experiments were conducted to examine the impact on kinetics of fiber digestion of microminerals and tryptone addition, media reduction, fermentation vessel, CO2 gassing regimen, and buffer type. Alfalfa and bromegrass hays were incubated for 0, 4, 8, 12, 18, 24, 30, 36, 48, 72, and 96 h and... | ['Animals', 'Buffers', 'Carbon Dioxide', 'Cattle', 'Dietary Fiber', 'Digestion', 'Female', 'Fermentation', 'Hydrogen-Ion Concentration', 'In Vitro Techniques', 'Kinetics', 'Medicago sativa', 'Poaceae', 'Rumen'] | 1,317,894 | [['B01.050'], ['D27.720.470.280'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['B01.050.150.900.649.313.500.380.271'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['G07.203.650.250', 'G10.261.190'], ['G02.111.158.249', 'G03.191.249'], ['G02.300'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['B01.650.94... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of reduced air pressure on dye penetration in standardized voids. | OBJECTIVE: This study determined the correlation between the degree of dye penetration in standardized voids to various reduced pressures.STUDY DESIGN: Standardized voids of 0.50 and 0.22 mm in diameter were created in 60 human roots; specimens were divided into five groups. Four groups were subjected to a 2% filtered ... | ['Air Pressure', 'Analysis of Variance', 'Coloring Agents', 'Dental Leakage', 'Dental Pulp Cavity', 'Dentin Permeability', 'Ethanol', 'Humans', 'Methylene Blue', 'Porosity', 'Solvents', 'Water'] | 8,680,981 | [['G16.500.750.274.100', 'N06.230.300.100.185.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.720.233'], ['C07.793.221'], ['A14.549.167.900.265'], ['G10.549.845.461'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.369.517', 'D03.633.300.783.517'], ['G01.374.... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Suppression of Basic Fibroblast Growth Factor Expression by Antisense Oligonucleotides Inhibits Neural Stem Cell Proliferation and Differentiation in Rat models With Focal Cerebral Infarction. | This study is designed to investigate the role of basic fibroblast growth factor (bFGF) antisense oligonucleotide (ASODN) on the proliferation and differentiation of neural stem cells (NSCs) in rat models with focal cerebral infarction (CI). Seventy-five Sprague-Dawlay (SD) rats were randomly divided into the control, ... | ['Animals', 'Cell Differentiation', 'Cell Proliferation', 'Cerebral Infarction', 'Fibroblast Growth Factor 2', 'Gene Expression Regulation', 'Neural Stem Cells', 'Oligodeoxyribonucleotides, Antisense', 'Rats', 'Rats, Sprague-Dawley'] | 28,390,174 | [['B01.050'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['G05.308'], [... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human-Bat Interactions in Rural West Africa. | Because some bats host viruses with zoonotic potential, we investigated human-bat interactions in rural Ghana during 2011-2012. Nearly half (46.6%) of respondents regularly visited bat caves; 37.4% had been bitten, scratched, or exposed to bat urine; and 45.6% ate bat meat. Human-bat interactions in rural Ghana are fre... | ['Animal Diseases', 'Animals', 'Chiroptera', 'Coronavirus Infections', 'Diet, Paleolithic', 'Disease Reservoirs', 'Disease Vectors', 'Ghana', 'Humans', 'Rural Population', 'Zoonoses'] | 26,177,344 | [['C22'], ['B01.050'], ['B01.050.150.900.649.313.937'], ['C01.925.782.600.550.200'], ['E02.642.249.275', 'G07.203.650.240.275'], ['N06.850.520.203.250'], ['N06.850.335.188', 'N06.850.520.203.375'], ['Z01.058.290.190.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.600.725'], ['C01.973', 'C22.969']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Predictive factors for metastatic infection in patients with bacteremia caused by methicillin-sensitive Staphylococcus aureus. | BACKGROUND: Metastatic infections such as infective endocarditis and psoas abscess are serious complications of Staphylococcus aureus bacteremia because failure to identify these infections may result in bacteremia relapse or poor prognosis. In the present study, we determined the predictive factors for metastatic infe... | ['Aged', 'Anti-Bacterial Agents', 'Bacteremia', 'C-Reactive Protein', 'Catheter-Related Infections', 'Female', 'Fever', 'Humans', 'Japan', 'Male', 'Methicillin', 'Retrospective Studies', 'Staphylococcal Infections', 'Staphylococcus aureus'] | 25,250,988 | [['M01.060.116.100'], ['D27.505.954.122.085'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['C01.195'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['D02.065.589.099.750.50... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Duration of the local anesthetic effect of tetracaine hydrochloride solutions and tetracaine in microspheres. | The local anesthetic effect of tetracaine in polylactic acid microspheres was compared with that of tetracaine hydrochloride solutions. As a first step, the local anesthetic effect of 0.1 ml tetracaine hydrochloride solutions was examined at four concentrations in vivo. Then, the local anesthetic effect of 0.2 ml tetra... | ['Anesthetics, Local', 'Animals', 'Delayed-Action Preparations', 'Guinea Pigs', 'Lactates', 'Lactic Acid', 'Male', 'Microspheres', 'Polyesters', 'Polymers', 'Solutions', 'Tetracaine', 'Time Factors'] | 7,077,517 | [['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['B01.050'], ['D26.255.210', 'E02.319.300.253'], ['B01.050.150.900.649.313.992.550'], ['D02.241.511.459'], ['D02.241.511.459.450'], ['E07.565'], ['D05.750.728', 'D25.720.728', 'J01.637.051.720.728'], ['D05.750', 'D25.720', 'J01.637.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Dependence of Ca2+ release from intracellular stores on NADH and FAD levels in fertilized and unfertilized bovine oocytes]. | Relation between NADH and FAD concentrations and the quantity of calcium released from intracellular stores in fertilized and unfertilized bovine oocytes was investigated using luminescent analysis. Inhibition of Ca2+ exit from intracellular stores was detected in degenerative oocytes at metaphase II and 2-cell embryos... | ['Animals', 'Biological Transport', 'Calcium', 'Cattle', 'Chlortetracycline', 'Female', 'Fertilization', 'Flavin-Adenine Dinucleotide', 'In Vitro Techniques', 'NAD', 'Oocytes'] | 16,706,214 | [['B01.050'], ['G03.143'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.500.380.271'], ['D02.455.426.559.847.562.900.146', 'D04.615.562.900.146'], ['G08.686.784.277'], ['D03.633.100.733.315.650.249', 'D03.633.100.759.646.138.506', 'D03.633.300.507.650.249', 'D08.211.474.650.249', 'D1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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