Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Self-judged comprehension in adults: effects of age and skill. | We used an error detection paradigm to examine the effects of skill on young (M = 23.74) and old (M = 68.87) adults' self-judged comprehension of texts. Skill was defined as the ability to evaluate comprehension by detecting text problems. Multiple regression results indicated that problematic texts produced lower comp... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Aptitude', 'Humans', 'Language Tests', 'Middle Aged', 'Self Concept', 'Self-Evaluation Programs'] | 1,446,692 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['F02.784.629.131'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513.240'], ['M01.060.116.630'], ['F01.752.747.792'], ['I02.399.780']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Combination of 5-fluorouracil and recombinant interferon alpha-2B in advanced gastric cancer. A phase I study. | Based on recent preclinical data suggesting synergism between 5-fluorouracil (5-FU) and interferon alpha (IFN-alpha) and clinical activity of the combination therapy in colon cancer, 14 patients with advanced gastric cancer were treated with combination therapy of 5-FU and recombinant interferon alpha-2b (rIFN alpha-2b... | ['Adult', 'Antineoplastic Combined Chemotherapy Protocols', 'Drug Administration Schedule', 'Drug Evaluation', 'Drug Synergism', 'Female', 'Fluorouracil', 'Humans', 'Infusions, Intravenous', 'Injections, Intravenous', 'Interferon alpha-2', 'Interferon-alpha', 'Male', 'Middle Aged', 'Recombinant Proteins', 'Stomach Neop... | 1,553,902 | [['M01.060.116'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.319.283'], ['E05.290.625', 'E05.337.425'], ['G07.690.773.968.477'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['E02.319.267.082.750', 'E02.319.267.530.54... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antigenic variation in alkaline deoxyribonuclease induced by three different strains of Epstein-Barr virus. | To determine whether biological and/or biochemical variants exist between strains of Epstein-Barr virus (EBV), we superinfected Raji cells with the nontransforming lytic strain of EBV (HR-1), and two isolates that both transform B-lymphocytes and superinfect Raji cells, B95-8, and NPC-EBV. The superinfected cells were ... | ['Antigenic Variation', 'Antigens, Viral', 'Cell Line', 'Deoxyribonucleases', 'Electrophoresis, Polyacrylamide Gel', 'Herpesvirus 4, Human', 'Humans', 'Neutralization Tests'] | 2,846,779 | [['G05.365.073', 'G12.500.249'], ['D23.050.327'], ['A11.251.210'], ['D08.811.277.352.335'], ['E05.196.401.402', 'E05.301.300.319'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.735.550', 'E05.200.812.735.550', 'E05.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Detached ciliary tufts in pouch of Douglas fluid. | Detached ciliary tufts were observed in fluid obtained during laparoscopy from the pouch of Douglas of a young woman with secondary infertility. Previous reports of this finding are reviewed, and various etiologic factors in the production of these structures are discussed. This phenomenon appears to be a normal physio... | ['Adult', 'Body Fluids', 'Cilia', "Douglas' Pouch", 'Epithelium', 'Female', 'Humans', 'Infertility', 'Laparoscopy'] | 2,943,105 | [['M01.060.116'], ['A12.207'], ['A11.284.180.165'], ['A01.923.047.025.600.225'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365', 'C13.351.500.365'], ['E01.370.388.250.520', 'E04.502.250.520']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Histology and histochemistry of the testis and ovary of the platyfish, Xiphophorus maculatus, from birth to sexual maturity. | The gonads of 3-day- to 7-month-old male and female platyfish (Xiphophorus maculatus) were examined for the presence of delta 5-3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) and glucose-6-phosphate dehydrogenase (G6PD) by histochemical means. In 3-day-old males a positive response for both enzymes is localized in th... | ['3-Hydroxysteroid Dehydrogenases', 'Animals', 'Female', 'Fishes', 'Glucosephosphate Dehydrogenase', 'Granulosa Cells', 'Leydig Cells', 'Male', 'Ovary', 'Sertoli Cells', 'Sexual Maturation', 'Testis'] | 6,954,006 | [['D08.811.682.047.436.350'], ['B01.050'], ['B01.050.150.900.493'], ['D08.811.682.047.150.300'], ['A05.360.319.114.630.535.200', 'A06.300.312.497.535.300', 'A11.382.812', 'A11.436.329'], ['A05.360.444.849.513', 'A06.300.312.782.513', 'A11.382.906', 'A11.436.513'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The inhibitory interaction between human corneal and conjunctival sensory channels. | PURPOSE: To explore human corneal and conjunctival sensory channels at suprathreshold level.METHODS: Ten healthy human subjects participated in the study. The Belmonte pneumatic esthesiometer was used to apply mechanical and chemical stimuli to the central cornea and temporal conjunctiva of the left eye. Stimuli were a... | ['Adult', 'Conjunctiva', 'Cornea', 'Female', 'Humans', 'Ion Channels', 'Male', 'Ophthalmic Nerve', 'Physical Stimulation', 'Sensation', 'Stimulation, Chemical'] | 15,790,886 | [['M01.060.116'], ['A09.371.060.200', 'A09.371.337.168'], ['A09.371.060.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['A08.800.800.120.760.650'], ['E05.723'], ['F02.830.816', 'G11.561.790'], ['G07.690.773.996']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Synthesis, mass spectral characterization and immunoadjuvant activity of some novel lipophilic derivatives of muramyl dipeptides. | Some novel lipophilic derivatives of N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP) have been prepared and rigorously evaluated by spectroscopic means. Fast atom bombardment and field desorption mass spectrometry provided information about both molecular weight and structural detail. The new MDP derivatives have been te... | ['Acetylmuramyl-Alanyl-Isoglutamine', 'Adjuvants, Immunologic', 'Animals', 'Female', 'Guinea Pigs', 'Indicators and Reagents', 'Magnetic Resonance Spectroscopy', 'Male', 'Mass Spectrometry', 'Pyrogens', 'Rabbits', 'Spectrophotometry, Infrared', 'Structure-Activity Relationship'] | 3,815,623 | [['D09.067.550.050', 'D09.811.522.050', 'D12.644.233.050'], ['D27.505.696.477.067'], ['B01.050'], ['B01.050.150.900.649.313.992.550'], ['D27.720.470.410'], ['E05.196.867.519'], ['E05.196.566'], ['D27.888.569.673'], ['B01.050.150.900.649.313.968.700'], ['E05.196.712.726.676', 'E05.196.867.826.676'], ['G02.111.830', 'G07... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Impact of Sleep Debt on Excess Adiposity and Insulin Sensitivity in Patients with Early Type 2 Diabetes Mellitus. | STUDY OBJECTIVES: We examined cross-sectional and prospective associations between sleep debt and adiposity measures, as well as homeostatic model assessment-insulin resistance (HOMA-IR) in early type 2 diabetes.METHODS: Prospective data analysis from participants of a randomized controlled trial based on an intensive ... | ['Adiposity', 'Body Mass Index', 'Comorbidity', 'Cross-Sectional Studies', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Insulin Resistance', 'Life Style', 'Male', 'Middle Aged', 'Obesity', 'Prospective Studies', 'Sleep', 'Sleep Deprivation', 'Time Factors', 'United Kingdom'] | 26,943,711 | [['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.45... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Persisting learning deficits in rats after exposure to Pfiesteria piscicida. | Pfiesteria piscicida and other toxic Pfiesteria-like dinoflagellates have been implicated as a cause of fish kills in North Carolina estuaries and elsewhere. Accidental laboratory exposure of humans to P. piscicida has been reported to cause a complex syndrome including cognitive impairment. The current project was con... | ['Animals', 'Dinoflagellida', 'Female', 'Learning Disabilities', 'Maze Learning', 'Motor Activity', 'Protozoan Infections, Animal', 'Rats', 'Rats, Sprague-Dawley'] | 9,405,328 | [['B01.050'], ['B01.043.214'], ['C10.597.606.150.550', 'C23.888.592.604.150.550', 'F03.625.562'], ['F02.463.425.874.500'], ['F01.145.632', 'G11.427.410.698'], ['C01.610.701.688', 'C01.610.752.625', 'C22.674.710'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750']] | ['Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A relationship between functional age and health status in female subjects. | A multiple regression equation was used to predict age from seven clinical variables in 1080 apparently well female subjects. A multiple correlation coefficient of R = 0.77 was achieved by five of the variables: timed forced expiratory volume, systolic blood pressure, plasma urea nitrogen, cholesterol, and alkaline pho... | ['Adult', 'Age Factors', 'Aged', 'Aging', 'Alkaline Phosphatase', 'Blood Glucose', 'Blood Sedimentation', 'Female', 'Health Status Indicators', 'Health Surveys', 'Humans', 'Male', 'Middle Aged', 'Regression Analysis', 'Smoking', 'Triglycerides'] | 950,448 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['G07.345.124'], ['D08.811.277.352.650.035'], ['D09.947.875.359.448.500'], ['E01.370.225.625.125', 'E05.200.625.125'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['E05.318.308.980.438', 'N05.71... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Nd:YAG laser with sapphire tip combined with balloon angioplasty in peripheral arterial occlusions. Long-term results. | In 167 patients with complete occlusion (greater than 3 cm) of the femoropopliteal artery, percutaneous transluminal laser angioplasty (PTLA) was performed after an unsuccessful attempt at crossing with a guide wire and was immediately followed by balloon dilatation. An Nd-YAG laser and an optical fiber delivery system... | ['Aged', 'Angioplasty, Balloon', 'Angioplasty, Laser', 'Arterial Occlusive Diseases', 'Aspirin', 'Dipyridamole', 'Female', 'Femoral Artery', 'Follow-Up Studies', 'Humans', 'Male', 'Phenprocoumon', 'Popliteal Artery', 'Recurrence', 'Time Factors'] | 1,824,621 | [['M01.060.116.100'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['E02.148.050.075', 'E02.594.060', 'E04.014.520.060', 'E04.100.814.529.124.075', 'E04.502.382.124.075', 'E05.157.016.075'], ['C14.907.137'], ['D02.455.426.559.389.657.410.595.176'], ['D03.383.742.175'], ['A07... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Total contribution of airborne lead to blood lead. | A nine year study of blood lead concentrations and isotope ratios carried out on a married couple shows that pulmonary deposition cannot account for all the airborne lead in blood; that lead from bone may comprise 70% of blood lead; and that during pregnancy blood lead may double due to mobilisation of lead from bone. | ['Adult', 'Air Pollutants', 'Bone and Bones', 'Diet', 'Female', 'Humans', 'Isotopes', 'Lead', 'Male', 'Pregnancy', 'Respiration', 'Time Factors'] | 3,970,881 | [['M01.060.116'], ['D27.888.284.101'], ['A02.835.232', 'A10.165.265'], ['G07.203.650.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.496'], ['D01.268.556.435', 'D01.552.544.435'], ['G08.686.784.769'], ['G09.772.705'], ['G01.910.857']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Human immunodeficiency virus transmission at each step of the care continuum in the United States. | IMPORTANCE: Human immunodeficiency virus (HIV) transmission risk is primarily dependent on behavior (sexual and injection drug use) and HIV viral load. National goals emphasize maximizing coverage along the HIV care continuum, but the effect on HIV prevention is unknown.OBJECTIVES: To estimate the rate and number of HI... | ['Adult', 'Aged', 'Anti-HIV Agents', 'Continuity of Patient Care', 'Disease Transmission, Infectious', 'Female', 'HIV Infections', 'Homosexuality, Male', 'Humans', 'Male', 'Middle Aged', 'Models, Statistical', 'Population Surveillance', 'Risk-Taking', 'Sexual Behavior', 'Substance Abuse, Intravenous', 'United States', ... | 25,706,928 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.388.077.088'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['N06.850.335'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['F01.145.802.975.500.600', 'G08.686.867.500.600... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Highly repetitive DNA sequence in parthenogenetic Artemia. | The study of the structural organization of the eukaryotic genome is one of the most important tools for disclosing the evolutionary relationships between species. Artemia (Crustacea, Phyllopoda) offers a very interesting model for speciation studies. The genus, distributed all over the world, comprises both bisexual s... | ['Animals', 'Artemia', 'Base Sequence', 'Biological Evolution', 'Chromosome Aberrations', 'Cloning, Molecular', 'DNA', 'Gene Frequency', 'Molecular Sequence Data', 'Parthenogenesis', 'Repetitive Sequences, Nucleic Acid', 'Restriction Mapping', 'Sex Characteristics'] | 1,901,366 | [['B01.050'], ['B01.050.500.131.365.060.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045', 'G16.075'], ['C23.550.210', 'G05.365.590.175'], ['E05.393.220'], ['D13.444.308'], ['G05.330'], ['L01.453.245.667'], ['G08.686.784.830.500', 'G15.547'], ['G02.111.570.080.708', 'G05.360.080.708'], ['E05.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Advanced glycation end products in idiopathic frozen shoulders. | BACKGROUND: The pathophysiologic mechanisms behind proliferation of fibroblasts and deposition of dense collagen matrix in idiopathic frozen shoulder remain unclear. Accumulation of advanced glycation end products (AGEs) with cross-linking and stabilization of collagen has been hypothesized to contribute to this pathop... | ['Adipocytes', 'Adolescent', 'Adult', 'Aged', 'Bursitis', 'Case-Control Studies', 'Cell Count', 'Cell Proliferation', 'Female', 'Fibroblasts', 'Glycation End Products, Advanced', 'Humans', 'Immunohistochemistry', 'Joint Instability', 'Male', 'Middle Aged', 'Prospective Studies', 'Range of Motion, Articular', 'Rotator C... | 26,776,943 | [['A11.329.114'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C05.550.251'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.329.228'], ['D12.776.643.500'], ['B... | ['Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of the Efficacy of a Diabetes Education Programme for Type 1 Diabetes (PRIMAS) in a Randomised Controlled Trial Setting and the Effectiveness in a Routine Care Setting: Results of a Comparative Effectiveness Study. | BACKGROUND: The effectiveness of an intervention in clinical practice is often reduced compared to the efficacy demonstrated in a randomised controlled trial (RCT). In this comparative effectiveness study, the RCT-proven efficacy of a diabetes education programme for type 1 diabetic patients (PRIMAS) was compared to th... | ['Adult', 'Comparative Effectiveness Research', 'Diabetes Mellitus, Type 1', 'Female', 'Glycated Hemoglobin A', 'Humans', 'Hypoglycemia', 'Male', 'Middle Aged', 'Patient Education as Topic', 'Treatment Outcome'] | 26,799,064 | [['M01.060.116'], ['H01.770.644.145.360.500', 'N05.425.157'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.984'], ['M01.060.116.630'], ['I02.233.332.... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
[Study of the host glycosyl component of the influenza virus using monoclonal antibodies]. | The crossreacting glycosylated host component (COHC) of influenza virus propagated in chick embryo has been studied using the monoclonal antibodies (MA). The specificity of MA to COHC has been demonstrated by different methods. Both MA of clones A9 and B7 react with the spatially overlapping antigenic sites of oligosac... | ['Animals', 'Antibodies, Monoclonal', 'Chick Embryo', 'Epitopes', 'Glycoproteins', 'Immunoenzyme Techniques', 'Influenza A virus', 'Oligosaccharides'] | 2,437,446 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A13.350.150', 'A16.331.200'], ['D23.050.550'], ['D09.400.430', 'D12.776.395'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['B04.820.480.968.405.400'], ['D09.698.629']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of human atrial natriuretic peptide on renal function and vasopressin release. | To assess the effects of atrial natriuretic peptide (ANP) on the renal function, cardiovascular system, renin-angiotensin-aldosterone system, and vasopressin release, synthetic human ANP (alpha-hANP) was administered at a dose of 0.08 microgram X kg-1 X min-1 iv for 40 min into anesthetized dogs (n = 6). In the control... | ['Aldosterone', 'Animals', 'Arginine Vasopressin', 'Atrial Natriuretic Factor', 'Blood Pressure', 'Diuresis', 'Dogs', 'Female', 'Glomerular Filtration Rate', 'Heart Rate', 'Humans', 'Kidney', 'Natriuresis', 'Potassium', 'Renal Circulation', 'Renin'] | 2,939,732 | [['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['B01.050'], ['D06.472.699.631.692.781.100', 'D12.644.400.900.100', 'D12.644.456.925.100', 'D12.644.548.691.692.781.100', 'D12.776.631.650.937.100'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G08.852.179'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Covalent changes in MIP26K during aging of the human lens membrane. | Rabbit antisera have been made to the C-terminal octapeptide of bovine MIP26K (residues 256-263) and to an octapeptide near the C-terminus (residues 252-259). Use of these antisera in Western blot analysis of membrane from young vs old human lenses, and from cortex vs nucleus of old human lenses, suggest age-related co... | ['Aging', 'Antibodies', 'Aquaporins', 'Eye Proteins', 'Humans', 'Lens, Crystalline', 'Membrane Glycoproteins', 'Membranes'] | 3,949,474 | [['G07.345.124'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.157.530.400.500.040', 'D12.776.543.550.450.730.040', 'D12.776.543.585.400.730.040'], ['D12.776.306'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.060.500'], ['D12.776.395.550', 'D12.776.543.550'... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nitric oxide mediates the inhibition of neutrophil migration induced by systemic administration of LPS. | To investigate the role of NO in the inhibition of neutrophil migration by circulating endotoxin, mice were pretreated with NO synthase inhibitors or with a free radical scavenger (D-penicillamine), before intravenous LPS injection. LPS dose-dependently inhibited the thioglycollate-induced neutrophil migration into the... | ['Animals', 'Chemotaxis, Leukocyte', 'Cytokines', 'Dose-Response Relationship, Drug', 'Enzyme Inhibitors', 'Guanidines', 'Lipopolysaccharides', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Neutrophils', 'Nitrates', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type II', 'Penicillamine'] | 11,580,101 | [['B01.050'], ['G04.198.424.233'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.389'], ['D02.078.370'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antitumor efficacy of 34.5ENVE: a transcriptionally retargeted and "Vstat120"-expressing oncolytic virus. | Here, we describe the construction and testing of a novel herpes simplex virus type 1 (HSV-1) derived oncolytic virus (OV): 34.5ENVE (viral ICP34.5 Expressed by Nestin promotor and Vstat120 Expressing), for the treatment of cancer. This virus showed significant glioma-specific killing and antiangiogenic effects in vitr... | ['Animals', 'Cell Line', 'Cell Movement', 'Cytopathogenic Effect, Viral', 'Endothelial Cells', 'Female', 'Gene Expression', 'Gene Order', 'Genetic Therapy', 'Genetic Vectors', 'Glioma', 'Herpesvirus 1, Human', 'Humans', 'Intermediate Filament Proteins', 'Mice', 'Mice, Nude', 'Necrosis', 'Neoplasms', 'Neovascularization... | 22,031,239 | [['B01.050'], ['A11.251.210'], ['G04.198', 'G07.568.500.180'], ['E01.370.225.500.384.235', 'E05.200.500.384.235', 'E05.242.384.235', 'G06.920.190'], ['A11.436.275'], ['G05.297'], ['G05.340'], ['E02.095.301', 'E05.393.420.301'], ['G05.360.337'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Experimental papillary necrosis of the kidney. II. Electron microscopic and histochemical studies. | Renal papillary necrosis was induced in rats by bromoethylamine hydrobromide and studied electron microscopically and histochemically. Morphologic changes appear to develop in vessels and tubules simultaneously, rather than tubular lesions preceding and leading to vascular lesions, or vice versa. Abnormalities are reco... | ['Adenosine Triphosphatases', 'Animals', 'Basement Membrane', 'Blood Platelets', 'Bromine', 'Cell Nucleus', 'Culture Techniques', 'Cytoplasm', 'Disease Models, Animal', 'Ethylamines', 'Female', 'Fibrin', 'Histocytochemistry', 'Kidney', 'Kidney Papillary Necrosis', 'L-Lactate Dehydrogenase', 'Microscopy, Electron', 'Rat... | 4,261,830 | [['D08.811.277.040.025'], ['B01.050'], ['A10.272.220', 'A10.615.179'], ['A11.118.188', 'A15.145.229.188'], ['D01.268.380.112'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E05.481.500'], ['A11.284.430.214'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.092.471'], ['D12.776.124.270'], ['E01.370.225.500... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Cases of numerous diffuse plaques in the neocortex but without severe senile changes in the hippocampus]. | Using modified Bielschowsky method, we studied neuropathologically 159 aged subjects autopsied during the period from 1976 to 1988, of which we found 19 cases (average age at death: 82.6 ys) with numerous diffuse plaques in the frontal and temporal neocortex and no severe senile changes in H1-H3 of Ammon's horn (dp gro... | ['Aged', 'Aged, 80 and over', 'Dementia', 'Female', 'Frontal Lobe', 'Hippocampus', 'Humans', 'Male', 'Temporal Lobe'] | 2,279,358 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380', 'F03.615.400'], ['A08.186.211.200.885.287.500.270'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.186.211.200.885.287.500.863']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Response to antiretroviral therapy after a single, peripartum dose of nevirapine. | BACKGROUND: A single dose of nevirapine during labor reduces perinatal transmission of human immunodeficiency virus type 1 (HIV-1) but often leads to viral nevirapine resistance mutations in mothers and infants.METHODS: We studied the response to nevirapine-based antiretroviral treatment among women and infants who had... | ['Adult', 'Anti-Retroviral Agents', 'Double-Blind Method', 'Drug Resistance, Viral', 'Drug Therapy, Combination', 'Female', 'Genotype', 'HIV Infections', 'HIV-1', 'Humans', 'Infant, Newborn', 'Infectious Disease Transmission, Vertical', 'Kaplan-Meier Estimate', 'Labor, Obstetric', 'Mutation', 'Nevirapine', 'Pregnancy',... | 17,215,531 | [['M01.060.116'], ['D27.505.954.122.388.077'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['G06.225.420', 'G06.920.225', 'G07.690.773.984.269.420'], ['E02.319.310'], ['G05.380'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Utilization of 5-bromouracil by thymineless bacteria. | Several thymineless Escherichia coli strains have been examined for their ability to replicate their deoxyribonucleic acid when bromouracil is substituted for thymine. The procedure we describe was used to identify a thymineless strain with characteristics relatively favorable to its use in bromouracil labeling experim... | ['Bromine', 'Carbon Isotopes', 'DNA, Bacterial', 'Escherichia coli', 'Mutation', 'Thymine', 'Tritium', 'Ultracentrifugation', 'Uracil'] | 5,335,905 | [['D01.268.380.112'], ['D01.268.150.075', 'D01.496.123'], ['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.365.590'], ['D03.383.742.698.875.899'], ['D01.268.406.875', 'D01.362.340.875', 'D01.496.749.925'], ['E05.181.724', 'E05.196.941'], ['D03.383.742.698.875']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Familial idiopathic gonadotropin deficiency: a hypothalamic form of hypogonadism. | To date, familial idiopathic gonadotropin deficiency (FIGD) has not been delineated as either a hypothalamic or a pituitary form of hypogonadism. Leydig cell sensitivity to human chorionic gonadotropin (HCG) has also been suggested as subnormal in FIGD. Also, in a few previously reported families the Kallmann syndrome ... | ['Female', 'Follicle Stimulating Hormone', 'Gonadotropin-Releasing Hormone', 'Gonadotropins', 'Humans', 'Hypogonadism', 'Hypothalamus', 'Luteinizing Hormone', 'Male', 'Sex Characteristics', 'Syndrome'] | 6,410,916 | [['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['D06.472.699.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.391.482'], ['A08.18... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Partial structural analysis of concanavalin A binding glycopeptides of large size from human teratocarcinoma-derived cells: cleavage by hydrazinolysis and alkaline borohydride. | Pronase digests of cultured teratocarcinoma-derived cells (PA 1) of human origin have been previously shown to contain large-sized glycopeptides (relative mass (Mr) greater then 7400), of which 15-23% are retained by columns of concanavalin A (Con A) - Sepharose and can be eluted with 10 mM methyl alpha-D-mannopyranosi... | ['Borohydrides', 'Cell Line', 'Chemical Phenomena', 'Chemistry', 'Female', 'Humans', 'Hydrazines', 'Hydrogen-Ion Concentration', 'Oligosaccharides', 'Ovarian Neoplasms', 'Receptors, Concanavalin A', 'Teratoma'] | 7,116,211 | [['D01.132.105.050', 'D02.203.087.050'], ['A11.251.210'], ['G02'], ['H01.181'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.442'], ['G02.300'], ['D09.698.629'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705'], ['D12.776.543.750.705.880.600'], ['C04.557.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Single-molecule imaging of a three-component ordered actin disassembly mechanism. | The mechanisms by which cells destabilize and rapidly disassemble filamentous actin networks have remained elusive; however, Coronin, Cofilin and AIP1 have been implicated in this process. Here using multi-wavelength single-molecule fluorescence imaging, we show that mammalian Cor1B, Cof1 and AIP1 work in concert throu... | ['Actin Cytoskeleton', 'Animals', 'Cofilin 1', 'Escherichia coli', 'Humans', 'Mice', 'Microfilament Proteins', 'Microscopy, Fluorescence', 'Rabbits', 'ras GTPase-Activating Proteins'] | 25,995,115 | [['A11.284.430.214.190.750.050'], ['B01.050'], ['D05.750.078.730.212.500', 'D12.776.220.525.212.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['D05.750.078.730', 'D12.776.220.525'], ['E01.370.350.515.458', 'E0... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predictors of oral health counseling by WIC providers. | PURPOSE: The purpose of this study was to assess selected predictors for the inclusion of oral health counseling by Illinois Women, Infants, and Children (WIC) providers.METHODS: A questionnaire was developed and mailed to all 166 WIC sites to assess attitudes towards oral health counseling. Variables that revealed sig... | ['Adult', 'Age Factors', 'Attitude to Health', 'Child', 'Child Health Services', 'Counseling', 'Educational Status', 'Female', 'Health Education, Dental', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Illinois', 'Infant', 'Male', 'Maternal Health Services', 'Middle Aged', 'Nurses', 'Nutritional Sciences', 'Oral H... | 17,367,031 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.100.150', 'N05.300.150'], ['M01.060.406'], ['N02.421.143.130'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['N01.824.196'], ['I02.233.332.374', 'N02.421.726.407.457', 'N06.890.410'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
cfDNA as a Prognostic Marker of Response to Taxane Based Chemotherapy in Patients with Prostate Cancer. | PURPOSE: Chemotherapy is an integral part of the treatment of castration resistant prostate cancer. With the introduction of new drugs the need to identify nonresponders is increasing. To our knowledge there are no prognostic parameters to date for use upon the initiation of any treatment.MATERIALS AND METHODS: cfDNA w... | ['Aged', 'Antineoplastic Agents', 'Biomarkers, Tumor', 'Bridged-Ring Compounds', 'DNA, Neoplasm', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Prostate-Specific Antigen', 'Prostatic Neoplasms, Castration-Resistant', 'Retrospective Studies', 'Survival Rate', 'Taxoids'] | 25,896,555 | [['M01.060.116.100'], ['D27.505.954.248'], ['D23.101.140'], ['D02.455.426.100', 'D04.075'], ['D13.444.308.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789'], ['D08.811.277.656.300.760.442.750', 'D08.811.277.656.959.350.442.750', 'D12.776.866.249.500', 'D23.050.285.625', 'D23.101.14... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Electrocardiographic changes in lepra reaction. | The electrocardiographic (E.C.G.) changes were evaluated in 54 patients of lepra reaction. Abnormalities of the E.C.G. observed were in the form of prolongation of QTc in 24 (44.44%), ST-T changes in a (16.66%), bundle branch block and ventricular extrasystoles in 2 each (3.70%). The mean QTc interval in 64 normal adul... | ['Adolescent', 'Adult', 'Electrocardiography', 'Female', 'Humans', 'Leprosy', 'Male', 'Middle Aged'] | 6,632,779 | [['M01.060.057'], ['M01.060.116'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.410.040.552.475.371'], ['M01.060.116.630']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ganciclovir-mediated elimination of HSV-Tk+ T cells and cure of graft-vs-host disease in an allogeneic bone marrow transplantation model in the rat. | OBJECTIVE: Suicide gene therapy for leukemia aims to benefit from T cells in the BM graft, by reducing the probability of leukemia relapse (GVL), while severe complications of graft-vs-host disease (GVHD) may be avoided. In an allogeneic rat BMT model we defined the conditions to induce a lethal GVHD with HSV-Tk gene-t... | ['Animals', 'Bone Marrow Transplantation', 'Ganciclovir', 'Genes, Transgenic, Suicide', 'Genetic Therapy', 'Graft vs Host Disease', 'Lymphocyte Depletion', 'Models, Animal', 'Rats', 'Rats, Inbred Strains', 'T-Lymphocytes', 'Transduction, Genetic', 'Transplantation, Homologous'] | 15,504,552 | [['B01.050'], ['E02.095.147.725.040', 'E04.936.580.040'], ['D03.633.100.759.758.399.454.250.300'], ['G05.360.340.024.340.825.500'], ['E02.095.301', 'E05.393.420.301'], ['C20.452'], ['E02.095.465.425.450.521', 'E05.478.610.570'], ['E05.598'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
New Fully Automated Method for Segmentation of Breast Lesions on Ultrasound Based on Texture Analysis. | The study described here explored a fully automatic segmentation approach based on texture analysis for breast lesions on ultrasound images. The proposed method involves two main stages: (i) In lesion region detection, the original gray-scale image is transformed into a texture domain based on log-Gabor filters. Local ... | ['Breast', 'Breast Neoplasms', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Pattern Recognition, Automated', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Ultrasonography, Mammary'] | 27,095,150 | [['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['L01.399.750'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Effect of PEEP on regional ventilation and perfusion in the mechanically ventilated preterm lamb. | Improvement of gas exchange through closer matching of regional ventilation (V) and lung perfusion (Q) with the application of positive end-expiratory pressure (PEEP) was evaluated in vivo in six mechanically ventilated preterm lambs (107-126 days/145 days gestation). Changes in V and Q were determined from in vivo sci... | ['Animals', 'Animals, Newborn', 'Krypton Radioisotopes', 'Lung', 'Positive-Pressure Respiration', 'Radionuclide Imaging', 'Sheep', 'Technetium Tc 99m Aggregated Albumin', 'Ventilation-Perfusion Ratio'] | 2,666,596 | [['B01.050'], ['B01.050.050.282'], ['D01.496.749.540'], ['A04.411'], ['E02.041.625.790', 'E02.880.820.790'], ['E01.370.350.710', 'E01.370.384.730'], ['B01.050.150.900.649.313.500.380.791'], ['D02.691.825.375', 'D12.776.034.900'], ['E01.370.386.700.650.900', 'G09.772.920']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Accumulation and distribution of dietary nickel in lake whitefish (Coregonus clupeaformis). | Benthic-feeding fish residing in Ni-contaminated systems are exposed to Ni through ingestion of contaminated food items and sediments. Lake whitefish (Coregonus clupeaformis) were fed diets at a ration of 0.5% of body weight three times a week containing 0, 10, 100, and 1000 microg Ni/g (as NiSO(4)) for 10, 31, and 104... | ['Administration, Oral', 'Animals', 'Biological Availability', 'Dose-Response Relationship, Drug', 'Environmental Exposure', 'Fresh Water', 'Nickel', 'Salmonidae', 'Tissue Distribution', 'Water Pollutants, Chemical'] | 12,007,878 | [['E02.319.267.100'], ['B01.050'], ['G03.787.151', 'G07.690.725.129'], ['G07.690.773.875', 'G07.690.936.500'], ['N06.850.460.350'], ['G16.500.275.280', 'N06.230.232'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.607'], ['B01.050.150.900.493.817.750'], ['G03.787.917', 'G07.690.725.949'], ['D27.888.284.903.655']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A Novel Rabbit Model for In-Stent Neoatherosclerosis. | In-stent neoatherosclerosis is an important problem after percutaneous coronary intervention. To explore the mechanisms and treatment of in-stent neoatherosclerosis, an animal model is needed. To avoid the disadvantages of current animal models, such as excessive use of X-rays and a high mortality rate, we attempted to... | ['Animals', 'Coronary Restenosis', 'Coronary Stenosis', 'Disease Models, Animal', 'Humans', 'Male', 'Neointima', 'Observer Variation', 'Percutaneous Coronary Intervention', 'Prosthesis Failure', 'Rabbits', 'Random Allocation', 'Risk Factors', 'Statistics, Nonparametric', 'Stents', 'Survival Rate', 'Tomography, Optical ... | 31,484,855 | [['B01.050'], ['C14.280.647.250.285.200', 'C14.907.585.250.285.200'], ['C14.280.647.250.285', 'C14.907.585.250.285'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.722'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E04.1... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Can NHS politics, power and conflict ever be a good thing for nurses? | This article explores how organisational politics, power and conflict have a positive role to play for nurses in NHS organisational change and improvement, rather than always leading to disagreement and dispute. | ['Dissent and Disputes', 'Health Care Reform', 'Humans', "Nurse's Role", 'Nurses', 'Politics', 'Power, Psychological', 'Quality Improvement', 'State Medicine', 'United Kingdom'] | 27,409,782 | [['F01.829.401.094', 'F02.463.785.373.476'], ['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.316.616.625.450', 'N05.300.100.337'], ['M01.526.485.650', 'N02.360.650'], ['I01.... | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Zebra mussel antifouling activity of the marine natural product aaptamine and analogs. | Several aaptamine derivatives were selected as potential zebra mussel (Dreissena polymorpha) antifoulants because of the noteworthy absence of fouling observed on Aaptos sponges. Sponges of the genus Aaptos collected in Manado, Indonesia consistently produce aaptamine-type alkaloids. To date, aaptamine and its derivati... | ['Animals', 'Araceae', 'Biological Products', 'Dreissena', 'Ecosystem', 'Inhibitory Concentration 50', 'Naphthyridines', 'Porifera', 'Survival Analysis', 'Time Factors', 'Toxicity Tests'] | 16,718,618 | [['B01.050'], ['B01.650.940.800.575.912.250.618.050.750'], ['D20.215'], ['B01.050.500.644.080.225'], ['G16.500.275.157', 'N06.230.124'], ['E05.940.350', 'G07.690.936.563'], ['D03.633.100.612'], ['B01.050.500.802'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.850.520.830.998'], ['G01.910.857'], ['E05.940']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A critical study on RO-4-1284 antagonism in mice. | Ro-4-1284 is found to produce ptosis, hypothermia, sedation and miosis in mice, and the antagonsim to these symptoms is investigated. The study reports the differential effects of various pharmacologically distinct classes of compounds. The relevance of this type of experiments to possible antidepressant drug activity ... | ['2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-', 'Analgesics', 'Animals', 'Antidepressive Agents, Tricyclic', 'Antihypertensive Agents', 'Body Temperature', 'Histamine H1 Antagonists', 'Male', 'Mice', 'Mice, Inbred Strains', 'Monoamine Oxidase Inhibitors', 'Motor Activity', 'Mu... | 240,331 | [['D03.633.100.834.700'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['D27.505.954.427.700.122.055'], ['D27.505.954.411.162'], ['E01.370.600.875.374', 'G07.110'], ['D27.505.519.625.375.425.400', 'D27.505.696.577.375.425.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Screening of reference genes and quantitative real-time PCR detection and verification in Dermatophagoides farinae under temperature stress. | Dermatophagoides farinae is an important source of indoor allergens that shows strong tolerance to external temperatures. However, the regularity and mechanism of tolerance are still unclear. Based on our previous RNA-seq and annotation of D. farinae under temperature stress, it is planned to identify differentially ex... | ['Animals', 'Antigens, Dermatophagoides', 'Calreticulin', 'DNA Primers', 'Dermatophagoides farinae', 'Female', 'Gene Amplification', 'Gene Expression Profiling', 'Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)', 'Molecular Sequence Annotation', 'RNA', 'Real-Time Polymerase Chain Reaction', 'Ribosomal Protei... | 31,473,211 | [['B01.050'], ['D23.050.181'], ['D12.644.360.372.374', 'D12.776.157.125.412.374', 'D12.776.476.387.374', 'D12.776.503.303'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B01.050.500.131.166.132.419.600.200'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['E05.393.332'], ['D08.811.682.657.163.750.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Analysis of the interaction of the human immunodeficiency virus type 1 gp120 envelope glycoprotein with the gp41 transmembrane glycoprotein. | The human immunodeficiency virus type 1 (HIV-1) gp120 exterior envelope glycoprotein interacts with the viral receptor (CD4) and with the gp41 transmembrane envelope glycoprotein. To study the interaction of the gp120 and gp41 envelope glycoproteins, we compared the abilities of anti-gp120 monoclonal antibodies to bind... | ['CD4 Antigens', 'Cell Line, Transformed', 'Epitopes', 'Gene Products, env', 'HIV Envelope Protein gp120', 'HIV Envelope Protein gp41', 'HIV-1', 'Humans', 'Recombinant Fusion Proteins', 'Sequence Deletion', 'Solubility', 'env Gene Products, Human Immunodeficiency Virus'] | 9,371,638 | [['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.894.100', 'D23.101.100.894.100'], ['A11.251.210.172'], ['D23.050.550'], ['D12.776.775.320', 'D12.776.964.775.325', 'D12.776.964.970.880.325'], ['D12.776.964.775.325.164.249', 'D12.776.964.775.562.500.500', 'D12.776.964.970.880.325.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determinants of oral self-care in the Brazilian adult population: a national cross-sectional study. | This study aims to investigate variables related to adherence to oral self-care in the Brazilian adult population. It is an exploratory study, using secondary data from a population-based survey on a representative sample of the adult population of the entire Brazilian territory (n=60202). The sample was selected using... | ['Adolescent', 'Adult', 'Age Factors', 'Brazil', 'Cross-Sectional Studies', 'Dental Health Surveys', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', 'Oral Health', 'Patient Compliance', 'Self Care', 'Sex Factors', 'Socioeconomic Factors', 'Young Adult'] | 29,267,676 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['Z01.107.757.176'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308.980.438.300', 'E06.208', 'N05.715.360.300.800.438.300', 'N06.850.520.308.980.438.300', 'N06.890.160'], ['F01.100.150.500', 'N05.300... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Responses to walking-speed instructions: implications for health promotion for older adults. | This study examined the effect of age on descriptive walking-speed instructions commonly used in health promotion. Participants were 9 young (20-23 years) and 9 older (75-83 years) women. Oxygen uptake and walking speed were measured in response to descriptive walking instructions ("slow," "comfortable," "brisk," and "... | ['Aged', 'Communication', 'Female', 'Health Promotion', 'Humans', 'Oxygen Consumption', 'Walking'] | 15,995,263 | [['M01.060.116.100'], ['F01.145.209', 'L01.143'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.680'], ['G11.427.410.568.900', 'G11.427.410.698.277.937', 'I03.350.937', 'I03.450.642.845.940']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
First report of Pennella balaenopterae Koren and Danielssen, 1877 (Copepoda: Pennelidae) from Turkey. | A parasitic copepod, Pennella balaenopterae Koren and Danielssen, 1877 (Copepoda: Pennelidae), has been reported from the fin whale, Balaenoptera physalus (Cetacaea: Mysticeti), which was found dead on the Avluk beach (Yumurtalik seaport, Iskenderun Bay, Northeastern Mediterranean coast of Turkey) in 6 May, 2002. This ... | ['Animals', 'Copepoda', 'Ectoparasitic Infestations', 'Female', 'Fin Whale', 'Male', 'Oceans and Seas', 'Turkey'] | 17,918,069 | [['B01.050'], ['B01.050.500.131.365.160'], ['C01.610.858.211'], ['B01.050.150.900.649.313.875.865.100.350'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.756'], ['Z01.252.245.500.850']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Inflamm-aging does not simply reflect increases in pro-inflammatory markers. | Many biodemographic studies use biomarkers of inflammation to understand or predict chronic disease and aging. Inflamm-aging, i.e. chronic low-grade inflammation during aging, is commonly characterized by pro-inflammatory biomarkers. However, most studies use just one marker at a time, sometimes leading to conflicting ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Female', 'Humans', 'Inflammation', 'Inflammation Mediators', 'Italy', 'Male', 'Middle Aged'] | 25,011,077 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['D23.469'], ['Z01.542.489'], ['M01.060.116.630']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Bastadin 12 and ryanodine reveal similarities between thapsigargin- and tetrabromobisphenol A-induced intracellular Ca(2+) release in cultured cerebellar granule cells. | Tetrabromobisphenol A (TBBPA) is a commonly used brominated flame retardant with recognized neuro- and cytotoxic properties that are presumably mediated by intracellular Ca(2+) release. Other studies have demonstrated that ryanodine is able to inhibit Ca(2+) efflux from skeletal sarcoplasmic reticulum (SR) membranes in... | ['Animals', 'Calcium', 'Cells, Cultured', 'Cerebellum', 'Halogenated Diphenyl Ethers', 'Peptides, Cyclic', 'Polybrominated Biphenyls', 'Rats, Wistar', 'Ryanodine', 'Thapsigargin'] | 25,371,527 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251'], ['A08.186.211.132.810.428.200'], ['D02.355.726.601', 'D02.455.426.559.389.657.654.601'], ['D04.345.566', 'D12.644.641'], ['D02.455.426.559.389.185.680', 'D02.455.526.368.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D02.455.84... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of acute administration of chlorinated water on liver lipids. | An acute administration of chlorinated water to rats caused "fatty liver" and indicated a more than 2-fold increase in liver triacylglycerols at 2 days after administration. The acyl group composition of triacylglycerols and phospholipids in both liver mitochondria and liver whole homogenate were also altered by the ch... | ['Animals', 'Fatty Acids, Unsaturated', 'Liver', 'Male', 'Phosphatidylcholines', 'Phospholipids', 'Rats', 'Sodium Hypochlorite', 'Triglycerides'] | 7,253,842 | [['B01.050'], ['D10.251.355'], ['A03.620'], ['D10.570.755.375.760.400.800'], ['D10.570.755'], ['B01.050.150.900.649.313.992.635.505.700'], ['D01.210.465.800', 'D01.650.550.400.800', 'D01.857.750'], ['D10.351.801']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Drug Distribution and Basic Pharmacology of Paclitaxel/Resveratrol-Coated Balloon Catheters. | PURPOSE: To experimentally investigate a new homogenously paclitaxel/resveratrol-coated balloon catheter in terms of transport of the coating to the treated tissue and local effects including histology and functional tests.METHODS: Adherence of the coating to the balloon was explored by in vitro simulation of its passa... | ['Angioplasty, Balloon', 'Angioplasty, Balloon, Coronary', 'Animals', 'Coated Materials, Biocompatible', 'In Vitro Techniques', 'Neointima', 'Paclitaxel', 'Resveratrol', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Stilbenes', 'Swine'] | 29,968,090 | [['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['B01.050'], ['D25.130.420'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
1HNMR-Based metabolomic profiling method to develop plasma biomarkers for sensitivity to chronic heat stress in growing pigs. | The negative impact of heat stress (HS) on the production performances in pig faming is of particular concern. Novel diagnostic methods are needed to predict the robustness of pigs to HS. Our study aimed to assess the reliability of blood metabolome to predict the sensitivity to chronic HS of 10 F1 (Large White ? Creol... | ['Animals', 'Biomarkers', 'Body Temperature Regulation', 'Climate', 'Heat Stress Disorders', 'Metabolomics', 'Proton Magnetic Resonance Spectroscopy', 'Swine'] | 29,176,781 | [['B01.050'], ['D23.101'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['G16.500.275.071', 'N06.230.300.100.250'], ['C26.522'], ['H01.158.201.586', 'H01.158.273.180.599', 'H01.181.122.638'], ['E05.196.867.519.775'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Noninvasive detection of fetal subchromosomal abnormalities by semiconductor sequencing of maternal plasma DNA. | Noninvasive prenatal testing (NIPT) using sequencing of fetal cell-free DNA from maternal plasma has enabled accurate prenatal diagnosis of aneuploidy and become increasingly accepted in clinical practice. We investigated whether NIPT using semiconductor sequencing platform (SSP) could reliably detect subchromosomal de... | ['Cell-Free System', 'Chromosome Aberrations', 'Chromosome Deletion', 'Chromosome Duplication', 'Comparative Genomic Hybridization', 'DNA', 'Female', 'Fetus', 'Humans', 'Molecular Weight', 'Pregnancy', 'Prenatal Diagnosis', 'Semiconductors', 'Sequence Analysis, DNA'] | 26,554,006 | [['A11.284.835.168'], ['C23.550.210', 'G05.365.590.175'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['C23.550.210.182', 'G05.365.590.175.183', 'G05.558.164'], ['E05.393.285.240', 'E05.393.520.500', 'E05.393.661... | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of process variables on photosynthetic algal hydrogen production. | Chlamydomonas reinhardtii is a green alga that can use the sun's energy to split water into O(2) and H(2). This is accomplished by means of a two-phase cycle, an aerobic growth phase followed by an anaerobic hydrogen production phase. The effects of process variables on hydrogen production are examined here. These vari... | ['Animals', 'Bioreactors', 'Cell Culture Techniques', 'Chlamydomonas', 'Combinatorial Chemistry Techniques', 'Dose-Response Relationship, Radiation', 'Hydrogen', 'Light', 'Photosynthesis', 'Temperature'] | 15,176,910 | [['B01.050'], ['E07.115', 'J01.897.120.115'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['B01.650.940.150.385'], ['E05.197.312', 'J01.897.836.249.249'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['D01.268.406', 'D01.362.34... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Topical Antibiotic Use Coselects for the Carriage of Mobile Genetic Elements Conferring Resistance to Unrelated Antimicrobials in Staphylococcus aureus. | Topical antibiotics, such as mupirocin and fusidic acid, are commonly used in the prevention and treatment of skin infections, particularly those caused by staphylococci. However, the widespread use of these agents is associated with increased resistance to these agents, potentially limiting their efficacy. Of particul... | ['Administration, Topical', 'Anti-Bacterial Agents', 'Bayes Theorem', 'Drug Resistance, Multiple, Bacterial', 'Fusidic Acid', 'Genome, Bacterial', 'Humans', 'Microbial Sensitivity Tests', 'Mupirocin', 'New Zealand', 'Staphylococcal Infections', 'Staphylococcal Skin Infections', 'Staphylococcus aureus'] | 29,229,636 | [['E02.319.267.120'], ['D27.505.954.122.085'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['D04.210.500.247.222.222.347.389', 'D04.210.500.247.808.489', 'D10.570.938.515'], ['G05.360.340... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Vulnerability to DNA damage in the aging rat substantia nigra: a study with the comet assay. | Oxidative DNA damage was measured in the substantia nigra (SN), cortex, hippocampus, striatum and hypothalamus of 3- and 24-month-old rats, using single-cell gel electrophoresis (SCGE, 'comet' assay) which allows the detection of DNA breaks and oxidized bases. A significant increase in basal DNA damage was selectively ... | ['Aging', 'Animals', 'Brain', 'Comet Assay', 'DNA Damage', 'DNA-Formamidopyrimidine Glycosylase', 'Male', 'N-Glycosyl Hydrolases', 'Nerve Degeneration', 'Rats', 'Rats, Wistar'] | 12,676,385 | [['G07.345.124'], ['B01.050'], ['A08.186.211'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.560.150'], ['G05.200'], ['D08.811.074.249.500', 'D08.811.277.450.430.099.500'], ['D08.811.277.450.430'], ['C23.550.737'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prospective randomized clinical trial comparing nitrous oxide and carbon dioxide pneumoperitoneum for laparoscopic surgery. | BACKGROUND: Recent publications demonstrating the safety and advantages of N2O for pneumoperitoneum (PP) prompted us to reconsider N2O as an agent for PP in general surgical laparoscopy. The purpose of this prospective, double-blind, randomized clinical trial was to determine whether N2O PP has any benefits over CO2 PP... | ['Adult', 'Aged', 'Carbon Dioxide', 'Double-Blind Method', 'Female', 'Fundoplication', 'Hemodynamics', 'Humans', 'Laparoscopy', 'Male', 'Middle Aged', 'Nitrous Oxide', 'Pain Measurement', 'Pneumoperitoneum, Artificial', 'Prospective Studies', 'Reoperation'] | 12,168,963 | [['M01.060.116'], ['M01.060.116.100'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E04.210.390'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The reactivity of human platelets in the 125I-labelled staphylococcal protein A test. | Stored platelets have been employed in the testing of various antiplatelet antibodies and platelet unrelated immune complexes. The antisera included sera containing ABO-,HLA- or platelet specific (ZWa) antibodies and serum from an adult patient with idiopathic thrombocytopenic purpura (ITP). Use was made of 125I-labell... | ['ABO Blood-Group System', 'Antigen-Antibody Complex', 'Blood Platelets', 'Cell Survival', 'Chromatography, Ion Exchange', 'Formaldehyde', 'HLA Antigens', 'Humans', 'Immune Sera', 'Immunoglobulin G', 'Indicators and Reagents', 'Iodine Radioisotopes', 'Neuraminidase', 'Purpura, Thrombocytopenic', 'Radioimmunoassay', 'St... | 568,872 | [['D23.050.301.290.031', 'D23.050.705.230.031'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['A11.118.188', 'A15.145.229.188'], ['G04.346'], ['E05.196.181.400.383'], ['D02.047.407'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['B01.050.150.900.649.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predictability of conjunctival-M?ellerectomy for blepharoptosis repair. | PURPOSE: To assess the predictability of the algorithm used to determine the amount of tissue resection for conjunctival-M?ellerectomy during blepharoptosis repair.METHODS: A consecutive case series of all patients undergoing conjunctival-M?ellerectomy during blepharoptosis repair between July 2001 and February 2005. A... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Algorithms', 'Blepharoplasty', 'Blepharoptosis', 'Child', 'Conjunctiva', 'Eyelids', 'Facial Muscles', 'Female', 'Humans', 'Male', 'Middle Aged', 'Phenylephrine', 'Treatment Outcome'] | 18,097,957 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G17.035', 'L01.224.050'], ['E04.540.104', 'E04.680.275.090'], ['C11.338.204'], ['M01.060.406'], ['A09.371.060.200', 'A09.371.337.168'], ['A01.456.505.420.504', 'A09.371.337'], ['A02.633.567.400', 'A14.363'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Quality assurance of digital mammography X-ray system]. | OBJECTIVE: To improve the performance quality of mammography X-ray system, and to decrease misdiagnoses.METHODS: Quality assurance was tested and controlled from such aspect as measurement of half value layer, beam quality assessment, breast entrance exposure average glandular dose, tube tunsion accuracy and reproducib... | ['Humans', 'Image Enhancement', 'Mammography', 'Quality Control', 'Radiographic Image Enhancement'] | 20,448,366 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.370.350.700.500'], ['J01.897.608'], ['E01.370.350.600.350.700', 'E01.370.350.700.700', 'L01.224.308.380.600']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Nicotine gum and theophylline metabolism. | When cigarette smokers with chronic lung disease stop smoking, they may do so with the aid of chewing nicotine gum. Smoking is known to accelerate the metabolism of theophylline, but the effects of nicotine gum on theophylline metabolism have not been determined. We studied the effects of nicotine and placebo gum on th... | ['Adult', 'Chewing Gum', 'Half-Life', 'Humans', 'Male', 'Middle Aged', 'Nicotine', 'Theophylline'] | 2,730,948 | [['M01.060.116'], ['D05.750.078.739.249', 'D09.698.700.249', 'D20.215.721.249.249', 'G07.203.300.140.200', 'J02.500.140.200'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D03.132.760.570', 'D03.383.725.518'], ['D03.132.960.751', 'D03.633.100.759.758.824.751']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Impact of physical therapist-directed exercise counseling combined with fitness center-based exercise training on muscular strength and exercise capacity in people with type 2 diabetes: a randomized clinical trial. | BACKGROUND: Assessing muscular strength (force-generating capacity) and exercise capacity in response to an intervention for people with type 2 diabetes is clinically important in the prevention of type 2 diabetes-related complications.OBJECTIVE: The purpose of this study was to investigate the impact of physical thera... | ['Adult', 'Aged', 'Analysis of Variance', 'Arkansas', 'Counseling', 'Diabetes Mellitus, Type 2', 'Exercise Therapy', 'Female', 'Fitness Centers', 'Humans', 'Male', 'Middle Aged', 'Muscle Strength', 'Physical Endurance', 'Physical Therapy Modalities', 'Resistance Training', 'Treatment Outcome', 'Universities'] | 19,589,851 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['Z01.107.567.875.750.110'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['C18.452.394.750.149', 'C19.246.300'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['J03.925.38... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Soci... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Characterization of a negative transcriptional element in the BRCA1 promoter. | INTRODUCTION: Decreased transcription of the BRCA1 gene has previously been observed to occur in sporadic breast tumours, making elucidation of the mechanisms regulating the expression of this gene important for our understanding of the etiology of the disease.METHODS: Transcriptional elements involved in the regulatio... | ['BRCA1 Protein', 'Blotting, Western', 'Breast Neoplasms', 'Chromatin Immunoprecipitation', 'DNA Methylation', 'DNA, Neoplasm', 'E2F6 Transcription Factor', 'GA-Binding Protein Transcription Factor', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Promoter Regions, Genetic', 'Regulatory Sequences, Nucleic Acid', '... | 17,663,789 | [['D12.776.313.125', 'D12.776.624.776.100', 'D12.776.660.100', 'D12.776.744.100', 'D12.776.930.137'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.588.180', 'C17.800.090.500'], ['E05.393.170', 'E05.478.605.160'], ['G02.111.035.538.161', 'G02.111.218', 'G03.0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Desmocytes in the calicoblastic epithelium of the stony coral Mycetophyllia reesi and their attachment to the skeleton. | Desmocytes scattered over the surface of the corallum of the scleractinian Mycetophyllia reesi attach the calicoblastic tissue to the skeleton. The structure of the desmocyte is generally consistent with that of other scleractinians except for their more rectangular profiles and greater size. However, the extent of att... | ['Animals', 'Basement Membrane', 'Cnidaria', 'Coloring Agents', 'Cytoskeleton', 'Epithelial Cells', 'Extracellular Matrix', 'Hemidesmosomes', 'Histological Techniques', 'Microscopy, Electron, Scanning', 'Ruthenium Red'] | 11,521,955 | [['B01.050'], ['A10.272.220', 'A10.615.179'], ['B01.050.500.308'], ['D27.720.233'], ['A11.284.430.214.190.750'], ['A11.436'], ['A11.284.295.310'], ['A11.284.149.165.165.360'], ['E01.370.225.750', 'E05.200.750'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D01.210.837', 'D01.625.800', 'D01.765.765']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Navigable networks as Nash equilibria of navigation games. | Common sense suggests that networks are not random mazes of purposeless connections, but that these connections are organized so that networks can perform their functions well. One function common to many networks is targeted transport or navigation. Here, using game theory, we show that minimalistic networks designed ... | ['Brain', 'Computer Communication Networks', 'Game Theory', 'Humans', 'Internet', 'Language', 'Protein Interaction Maps', 'Transportation'] | 26,138,277 | [['A08.186.211'], ['L01.224.230.110'], ['G17.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['F01.145.209.399', 'L01.559'], ['G03.493.750'], ['J01.937']] | ['Anatomy [A]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Performance improvement of raw water pretreatment process with pre-inoculation biofilm: feasibility and limiting factors. | The initial formation of biofilm and the removal performance of pollutants in biological pretreatment process for polluted raw water were limited due to the oligotrophic niche in raw water. In this study, the feasibility of using pre-inoculation biofilm formed under nutrients enhanced condition for polluted raw water t... | ['Biodegradation, Environmental', 'Biofilms', 'Bioreactors', 'Feasibility Studies', 'Risk Assessment', 'Rivers', 'Water Pollutants, Chemical', 'Water Purification'] | 27,913,890 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['A20.593', 'G06.120'], ['E07.115', 'J01.897.120.115'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['G0... | ['Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Core transcription factors, Oct4, Sox2 and Nanog, individually form complexes with nucleophosmin (Npm1) to control embryonic stem (ES) cell fate determination. | Embryonic stem (ES) cells have therapeutic potential in regenerative medicine, although the molecular mechanism controlling their pluripotency is not completely understood. Depending on interaction partners most proteins can be involved in several different cellular mechanisms. We screened for novel protein-protein int... | ['Animals', 'Biomarkers, Tumor', 'Cell Differentiation', 'Embryonic Stem Cells', 'Homeodomain Proteins', 'Mice', 'Multiprotein Complexes', 'Nanog Homeobox Protein', 'Nuclear Proteins', 'Octamer Transcription Factor-3', 'Protein Interaction Mapping', 'RNA, Small Interfering', 'SOXB1 Transcription Factors'] | 21,076,177 | [['B01.050'], ['D23.101.140'], ['G04.152'], ['A11.872.700.250'], ['D12.776.260.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['D05.500'], ['D12.776.260.400.530', 'D12.776.930.542'], ['D12.776.660'], ['D12.776.260.655.500.300', 'D12.776.930.710.500.300'], ['E05.601.690'], ['D13.150.650.700', 'D13.444.735.150.700',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment of stage IIIA Hodgkin's disease. | Current treatment for stage IIIA Hodgkin's disease consists of total nodal radiation therapy or a combination of radiation therapy (RT) and chemotherapy. In most series, 50%-65% of stage III2A patients receiving RT alone have a 5-year disease-free survival (DFS); when chemotherapy is added to RT, the percent of patient... | ['Antineoplastic Agents', 'Drug Therapy, Combination', 'Hodgkin Disease', 'Humans', 'Radiotherapy', 'Recurrence'] | 7,074,654 | [['D27.505.954.248'], ['E02.319.310'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.815'], ['C23.550.291.937']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ligand binding to transmembrane receptors on intact cells or membrane vesicles measured in a homogeneous 1-microliter assay format. | We have developed homogeneous miniaturized assays to measure ligand binding to either intact cells or receptor-containing membrane fragments by analysis of particle brightness. As an example, the affinities and inhibition constants of fluorescently labeled interleukin-8 (IL-8) and a low-molecular-weight antagonist towa... | ['Animals', 'CHO Cells', 'Cell Membrane', 'Cell Survival', 'Cell-Free System', 'Cricetinae', 'Heterotrimeric GTP-Binding Proteins', 'Interleukin-8', 'Kinetics', 'Ligands', 'Liposomes', 'Miniaturization', 'Receptors, Cell Surface', 'Receptors, Interleukin-8A', 'Sensitivity and Specificity'] | 11,689,112 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['A11.284.149'], ['G04.346'], ['A11.284.835.168'], ['B01.050.150.900.649.313.992.635.075.250'], ['D08.811.277.040.330.300.200', 'D12.644.360.360', 'D12.776.157.325.332', 'D12.776.476.375', 'D12.776.543.325'], ['D12.644.276.374.200.120.800', 'D12.644.276.374.465.312', 'D... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Anti-endothelial cell antibodies from patients with thrombotic thrombocytopenic purpura specifically activate small vessel endothelial cells. | Thrombotic thrombocytopenic purpura (TTP) is an uncommon disease of an unknown etiology, characterized by consumptive thrombocytopenia, microangiopathic hemolytic anemia, fever and acute thrombotic complications, especially within the cerebral circulation. Although anti-endothelial cell antibodies (AECA) have occasiona... | ['Antibody Specificity', 'Autoantibodies', 'Binding Sites, Antibody', 'Biomarkers', 'Bone Marrow Cells', 'Cell Adhesion', 'Cell Line', 'Cell Line, Transformed', 'Endothelium, Vascular', 'Humans', 'Interleukin-6', 'Microcirculation', 'Monocytes', 'Purpura, Thrombotic Thrombocytopenic', 'Thrombomodulin', 'von Willebrand ... | 11,157,853 | [['G12.100'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['G02.111.570.060.425.079', 'G02.111.570.120.408', 'G12.122.232', 'G12.125'], ['D23.101'], ['A11.148', 'A15.378.316'], ['G04.022'], ['A11.251.210'], ['A11.251.210.172'], ['A07.015.700.500', 'A10.272.491.355'], [... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Therapy with immunoglobulin suppresses myocarditis in a murine coxsackievirus B3 model. Antiviral and anti-inflammatory effects. | BACKGROUND: The treatment of some inflammatory diseases (eg, Kawasaki disease) with immunoglobulin has been demonstrated to be effective. Accordingly, to elucidate the mechanism underlying such actions of immunoglobulin, we examined its effects on murine coxsackievirus B3 (CB3) myocarditis.METHODS AND RESULTS: An in vi... | ['Animals', 'Antibodies, Viral', 'B-Lymphocytes', 'Coxsackievirus Infections', 'Enterovirus B, Human', 'Immunization, Passive', 'Male', 'Mice', 'Mice, Inbred C3H', 'Myocarditis'] | 7,664,447 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['C01.925.782.687.359.213'], ['B04.820.578.750.284.182'], ['E02.095.465.425.400.330', 'E05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anisotropic freeze-cast collagen scaffolds for tissue regeneration: How processing conditions affect structure and properties in the dry and fully hydrated states. | Few systematic structure-property-processing correlations for directionally freeze-cast biopolymer scaffolds are reported. Such correlations are critical to enable scaffold design with attractive structural and mechanical cues in vivo. This study focuses on freeze-cast collagen scaffolds with three different applied co... | ['Anisotropy', 'Biocompatible Materials', 'Collagen', 'Freezing', 'Mechanical Phenomena', 'Regeneration', 'Structure-Activity Relationship', 'Tissue Engineering', 'Tissue Scaffolds'] | 30,399,564 | [['G01.590.040', 'G02.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['G01.374'], ['G16.762'], ['G02.111.830', 'G07.690.773.997'], ['E05.481.500.311.500', 'J01.293.069.249.500'], ['E07.206.627', 'E07.695.825']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Immobilization of Clostridium thermocellum cells on bituminous coal particles. | The immobilization isotherms of Clostridium thermocellum cells on bituminous coal particles of approximately 0.15- to 0.18-mm diameter were experimentally measured at 60, 45, and 30 degrees C with a pH value of 7.0 and with pH values of 6.0 and 5.0 at 60 degrees C. The immobilization data were correlated into Langmuir ... | ['Adsorption', 'Bacteriological Techniques', 'Clostridium', 'Coal', 'Thermodynamics'] | 6,344,692 | [['G01.030', 'G02.020'], ['E01.370.225.875.150', 'E05.200.875.150'], ['B03.300.390.400.200', 'B03.353.625.375.500', 'B03.510.415.400.200'], ['D20.345.108', 'N06.230.132.258.108'], ['G01.906']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Impaired dendritic-cell function in ectodermal dysplasia with immune deficiency is linked to defective NEMO ubiquitination. | Ectodermal dysplasia with immune deficiency (EDI) is caused by alterations in NEMO (nuclear factor [NF]-kappaB essential modulator). Most genetic mutations are located in exon 10 and affect the C-terminal zinc finger domain. However, the biochemical mechanism by which they cause immune dysfunction remains undetermined.... | ['Arginine', 'CD3 Complex', 'CD40 Antigens', 'Cell Proliferation', 'Cysteine', 'Dendritic Cells', 'Ectodermal Dysplasia', 'Exons', 'Humans', 'I-kappa B Kinase', 'Immunologic Deficiency Syndromes', 'Mutation', 'Protein Structure, Tertiary', 'Ubiquitin', 'Zinc Fingers'] | 16,794,254 | [['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D23.050.301.264.894.095', 'D23.101.100.894.095'], ['D12.776.465.750', 'D12.776.543.750.705.852.760.097', 'D23.050.301.264.051.140', 'D23.101.100.150.140'], ['G04.161.750', 'G07.345.249.410.750'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Developmental and health services in head start preschools: a tiered approach to early intervention. | OBJECTIVE: To describe a tiered approach to identifying and addressing developmental and health concerns among low-income preschool children in Head Start.METHODS: Analytic sample consisted of 3- to 5-year-old Head Start students (n = 1171) from 14 centers in Los Angeles County serving predominantly Latino families dur... | ['Child Health Services', 'Child, Preschool', 'Developmental Disabilities', 'Early Intervention, Educational', 'Education, Special', 'Female', 'Humans', 'Logistic Models', 'Los Angeles', 'Male', 'Mass Screening', 'Mental Health Services', 'Needs Assessment', 'Odds Ratio', 'Referral and Consultation', 'Risk Assessment',... | 23,498,081 | [['N02.421.143.130'], ['M01.060.406.448'], ['F03.625.421'], ['N02.421.143.130.320', 'N02.421.726.320'], ['I02.233.213'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450',... | ['Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Using surface-enhanced Raman spectroscopy and electrochemically driven melting to discriminate Yersinia pestis from Y. pseudotuberculosis based on single nucleotide polymorphisms within unpurified polymerase chain reaction amplicons. | The development of sensors for the detection of pathogen-specific DNA, including relevant species/strain level discrimination, is critical in molecular diagnostics with major impacts in areas such as bioterrorism and food safety. Herein, we use electrochemically driven denaturation assays monitored by surface-enhanced ... | ['Bacterial Proteins', 'Base Sequence', 'Chaperonin 60', 'DNA, Bacterial', 'DNA, Single-Stranded', 'Electrochemistry', 'Genome, Bacterial', 'Molecular Sequence Data', 'Plague', 'Polymerase Chain Reaction', 'Polymorphism, Single Nucleotide', 'Species Specificity', 'Spectrum Analysis, Raman', 'Yersinia pestis', 'Yersinia... | 25,551,670 | [['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.277.040.025.142.500.500', 'D12.776.580.216.210.590.750'], ['D13.444.308.212'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['H01.181.529.307'], ['G05.360.340.358.207'], ['L01.453.245.667'], ['C01.150.252.400.31... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
CD40-CD40L interactions induce chemokine expression by human microglia: implications for human immunodeficiency virus encephalitis and multiple sclerosis. | CD40 is a protein on microglia that is up-regulated with interferon (IFN)-gamma and is engaged by CD40L, found on CD4+ T cells, B cells, and monocytes. These interactions may be important in central nervous system inflammatory diseases. Microglia have been shown to be a source of chemokines, whose expression plays a ke... | ['Adolescent', 'Adult', 'Antigens, CD', 'Antigens, Differentiation, Myelomonocytic', 'Brain', 'CD40 Antigens', 'CD40 Ligand', 'Cells, Cultured', 'Chemokines', 'Child', 'Encephalitis, Viral', 'Female', 'HIV Infections', 'Humans', 'Infant', 'Interferon-gamma', 'Male', 'Microglia', 'Middle Aged', 'Mitogen-Activated Protei... | 11,839,576 | [['M01.060.057'], ['M01.060.116'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.900', 'D23.101.100.900'], ['A08.186.211'], ['D12.776.465.750', 'D12.776.543.750.705.852.760.097', 'D23.050.301.264.051.140', 'D23.101.100.150.140'], ['D12.644.276.374.750.124', 'D12.776.395.550.185', 'D12.776.467.374.750.12... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Light-to-moderate alcohol drinking reduces the impact of obesity on the risk of diabetes mellitus. | OBJECTIVE: Light-to-moderate alcohol drinking has been shown to reduce the risk of type 2 diabetes, for which obesity is a primary risk factor. The aim of this study was to determine whether drinking alcohol influences the relationship between obesity and hyperglycemia.METHOD: The relationships of adiposity indices wit... | ['Adult', 'Alcohol Drinking', 'Body Mass Index', 'Diabetes Mellitus, Type 2', 'Glycated Hemoglobin A', 'Humans', 'Hyperglycemia', 'Male', 'Middle Aged', 'Obesity', 'Risk Factors', 'Waist Circumference'] | 25,343,662 | [['M01.060.116'], ['F01.145.317.269'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C18.452.394.750.149', 'C19.246.300'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Use of weight-for-height indices in children to predict adult overweight: the Bogalusa Heart Study. | OBJECTIVE: To compare the body mass index (BMI) (weight/height2) and the Ponderal index (PI) (weight/height3) in childhood as predictors of adult overweight in a biracial group of children.DESIGN: Prospective, 15-y follow-up.SUBJECTS: 835 children aged 10-15 y at baseline.MEASUREMENTS: Weight in kg and height in m.OUTC... | ['Adolescent', 'Adult', 'African Continental Ancestry Group', 'Aging', 'Anthropometry', 'Body Height', 'Body Mass Index', 'Body Weight', 'Child', 'European Continental Ancestry Group', 'Humans', 'Louisiana', 'Obesity', 'Predictive Value of Tests', 'Prospective Studies', 'Regression Analysis', 'Risk Factors'] | 8,856,393 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.100'], ['G07.345.124'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The effects of systemic administration and local microinjection into the central nervous system of the selective serotonin 5-HT2C receptor agonist RO-600175 on sleep and wakefulness in the rat. | The effects of RO-600175, a selective 5-HT2C receptor agonist, were studied in adult rats implanted for chronic sleep recordings. Intraperitoneal administration of RO-600175 (4 mg/kg) during the light phase of the light-dark cycle significantly increased wakefulness and reduced slow wave sleep and rapid-eye-movement sl... | ['Animals', 'Cerebral Cortex', 'Dorsal Raphe Nucleus', 'Electrodes, Implanted', 'Ethylamines', 'Indoles', 'Male', 'Microinjections', 'Photoperiod', 'Rats, Wistar', 'Receptor, Serotonin, 5-HT2C', 'Serotonin 5-HT2 Receptor Agonists', 'Sleep', 'Tegmentum Mesencephali', 'Wakefulness'] | 25,932,720 | [['B01.050'], ['A08.186.211.200.885.287.500'], ['A08.186.211.132.659.413.875.618.249'], ['E07.305.250.319', 'E07.695.202'], ['D02.092.471'], ['D03.633.100.473'], ['E02.319.267.530.690', 'E05.591.570'], ['G01.910.675'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D12.776.543.750.670.800.200.200', 'D12.776.543.750... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Safe handling of chemotherapy in the perioperative setting. | Safe handling of chemotherapeutic agents during administration and disposal is critical. Most antineoplastic agents are toxic compounds that are carcinogenic, mutagenic, or teratogenic. Direct contact may cause irritation of the skin, eyes, and mucous membranes. Perioperative personnel should know how to handle hazardo... | ['Antineoplastic Agents', 'Documentation', 'Drug Labeling', 'Evidence-Based Practice', 'Hazardous Substances', 'Humans', 'Intraoperative Care', 'Medical Waste Disposal', "Nurse's Role", 'Nursing Records', 'Occupational Exposure', 'Occupational Health', 'Operating Room Nursing', 'Patient Care Planning', 'Patient Educati... | 20,362,210 | [['D27.505.954.248'], ['L01.453.245'], ['E05.916.310', 'J01.576.655.750.321.400', 'J01.576.761.300.400'], ['H02.249'], ['D27.888.426'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.731.400', 'E04.604.249', 'N02.421.585.722.400'], ['D20.944.460.300', 'N06.850.460.710.460.300', 'N06.850.860.510.900.600.600'... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Soc... | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 |
Diagnosis of biceps tendon dislocation by kinematic magnetic resonance imaging. | Biceps tendon dislocation is an uncommon condition that may be overlooked due to its association with more common shoulder pathology. Diagnosis may be further obscured by the difficulty of palpating the biceps tendon in a muscular or obese patient. We present a patient with a dislocating biceps tendon in which the diag... | ['Adult', 'Arm', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Palpation', 'Range of Motion, Articular', 'Recurrence', 'Rotation', 'Tendon Injuries'] | 8,922,171 | [['M01.060.116'], ['A01.378.800.075'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E01.370.600.600'], ['E01.370.600.700', 'G11.427.760'], ['C23.550.291.937'], ['G01.482.703'], ['C26.874']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Variability and predictors of urinary phthalate metabolites in Spanish pregnant women. | Developmental exposure to phthalates may be associated with adverse health outcomes but information on the variability and predictors of urinary phthalate metabolite concentrations during pregnancy is limited. We evaluated in Spanish pregnant women (n=391) the reproducibility of urinary phthalate metabolite concentrati... | ['Adolescent', 'Adult', 'Body Mass Index', 'Cohort Studies', 'Cosmetics', 'Creatinine', 'Drinking Water', 'Eating', 'Educational Status', 'Female', 'Food Packaging', 'Household Products', 'Humans', 'Life Style', 'Linear Models', 'Maternal Exposure', 'Phthalic Acids', 'Pregnancy', 'Pregnancy Trimester, First', 'Pregnanc... | 25,558,797 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D27.720.269', 'J01.516.213'], ['D03.383.129.308.207'], ['D01.045.250.875.300', 'D01.248.497.158.459.650.300', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenome... | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Immediate radical cystectomy vs conservative management for high grade cT1 bladder cancer: is there a survival difference? | OBJECTIVE: To determine whether a survival difference exists between patients with high grade (HG) cT1 urothelial cell carcinoma (UCC) receiving immediate radical cystectomy (IRC) as opposed to those choosing bladder-sparing therapy.PATIENTS AND METHODS: Between January 1990 and August 2010, 349 patients were retrospec... | ['Administration, Intravesical', 'Aged', 'BCG Vaccine', 'Carcinoma, Transitional Cell', 'Cystectomy', 'Disease-Free Survival', 'Female', 'Humans', 'Male', 'Neoplasm Recurrence, Local', 'Survival Rate', 'Urinary Bladder Neoplasms'] | 22,487,512 | [['E02.319.267.120.505'], ['M01.060.116.100'], ['D20.215.894.135.825.100'], ['C04.557.470.200.430'], ['E04.950.774.150'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
HLA DR4 and rheumatoid arthritis in Japanese people. | Eighty-eight Japanese patients with rheumatoid arthritis and 104 normal Japanese persons were typed for HLA A, B, C, and DR antigens. The frequency of HLA DR4 was 70.5% in patients compared with 46.1% in normal controls (P less than 0.001). However, a sex difference in the frequency of HLA DR4 in patients was noted. HL... | ['Adult', 'Aged', 'Arthritis, Rheumatoid', 'Asian Continental Ancestry Group', 'Female', 'HLA Antigens', 'HLA-DR4 Antigen', 'Histocompatibility Antigens Class II', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Sex Factors'] | 6,972,742 | [['M01.060.116'], ['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['M01.686.508.200'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['D12.776.395.550.509.400.440.400.040', 'D12.776.543.550.440.400.440.400.040', 'D23.050.301.500.400.400.440.400.040', 'D23.050.301.500.450.400... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Could capillary zone electrophoresis of tryptic peptides be used for the characterization of hemoglobin variants? | The present article describes a simple and rapid new peptide mapping procedure that could be used to assist identification of rare hemoglobin variants in clinical laboratories. Four hemoglobin variants were taken as example, namely Hb D-Ouled Rabah, Hb Marseille, Hb G-Philadelphia, and Hb Ube-2, and isolated by electro... | ['Amino Acid Sequence', 'Electrophoresis, Capillary', 'Genetic Variation', 'Globins', 'Hemoglobins, Abnormal', 'Humans', 'Peptide Fragments', 'Peptide Mapping', 'Reproducibility of Results', 'Trypsin'] | 11,570,719 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.401.190', 'E05.301.300.190'], ['G05.365'], ['D12.776.422.316'], ['D12.776.124.400.463', 'D12.776.422.316.762.426'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.541'], ['E05.196.181.400.454.720', 'E05.196.401.319.720', 'E05.196.700', 'E05.393.760.705.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Osteon remodeling dynamics in the Cayo Santiago Macaca mulatta: The effect of matriline. | At the microstructural level, bones remodel throughout life. This process is recorded in bone cortex as osteons. A more comprehensive understanding of the interaction between genetic regulation and environmental factors in osteon remodeling will increase the value of this skeletal record and enable more accurate recons... | ['Age Factors', 'Analysis of Variance', 'Animals', 'Bone Remodeling', 'Female', 'Femur', 'Haversian System', 'Inheritance Patterns', 'Macaca mulatta', 'Male', 'Sex Factors'] | 12,884,317 | [['N05.715.350.075', 'N06.850.490.250'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G11.427.213', 'G16.762.150'], ['A02.835.232.043.150'], ['A10.165.265.521.500'], ['G05.420'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['N05.715.350.675', 'N06.850.490.875']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Factors associated with failed treatment: an analysis of 121,744 women embarking on their first IVF cycles. | BACKGROUND: In-vitro fertilization (IVF) is the treatment of choice for unresolved infertility. It comprises a number of key steps, each of which has to be negotiated before the next is attempted, but the factors which are associated with failure at each stage have not been reported.METHODS AND FINDINGS: We analyzed an... | ['Embryo Transfer', 'Female', 'Fertilization in Vitro', 'Humans', 'Live Birth', 'Male', 'Oocytes', 'Ovary', 'Pregnancy', 'Pregnancy Tests', 'Risk Factors', 'Spermatozoa', 'Treatment Failure'] | 24,349,236 | [['E02.875.800.500', 'E05.820.800.500'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.496.249'], ['A05.360.490.690.680', 'A11.497.497.600'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['G08.686.784.769'], ['E01.370.225.970', 'E01.370.378.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Relationship between the prognostic and predictive value of the intrinsic subtypes and a validated gene profile predictive of loco-regional control and benefit from post-mastectomy radiotherapy in patients with high-risk breast cancer. | BACKGROUND: Breast cancer is characterized by great molecular heterogeneity demonstrated, e.g. by the intrinsic subtypes. Administration of post-mastectomy radiotherapy (PMRT) does, however, not reflect this heterogeneity. A gene profile (DBCG-RT profile) has recently been developed and validated, and has shown prognos... | ['Antineoplastic Agents, Hormonal', 'Antineoplastic Combined Chemotherapy Protocols', 'Breast Neoplasms', 'Chemoradiotherapy', 'Cyclophosphamide', 'ErbB Receptors', 'Female', 'Fluorouracil', 'Gene Expression Profiling', 'Humans', 'Immunohistochemistry', 'Ki-67 Antigen', 'Lymph Node Excision', 'Mastectomy', 'Methotrexat... | 24,957,550 | [['D27.505.954.248.169'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.180', 'C17.800.090.500'], ['E02.186.079', 'E02.319.164', 'E02.815.160'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Specific antibody modulates absorptive transport and metabolic activation of benzo[a]pyrene across Caco-2 monolayers. | It has been shown that oral anticarcinogen antibodies can decrease intestinal absorption of procarcinogens. So far, no attempts have been made to understand the potential modulatory effect of such antibodies on metabolic activation at mucosal surfaces. Moreover, the influence of naturally induced serosal-specific antib... | ['Absorption', 'Animals', 'Antibodies, Monoclonal', 'Antibodies, Neoplasm', 'Antibody Specificity', 'Benzo(a)pyrene', 'Biological Transport', 'Biotransformation', 'Caco-2 Cells', 'Carcinogens', 'Epithelium', 'Humans', 'Intracellular Space', 'Mice'] | 15,665,140 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.240', 'D12.776.124.790.651.114.240', 'D12.776.377.715.548.114.240'], ['G12.100'], ['D02.455.426.559.847.799.306.300'... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Is Circular Fibrin Sealing of Low Rectal Anastomosis Able to Prevent Leakage in 21-Day Follow-up? Randomized Experimental Trial in Pigs. | Purpose. Clinically apparent anastomotic leakage (AL) after low anterior rectal resection (LAR; <7 cm from anal verge) using circular double-stapled anastomosis without defunctioning stoma is up to 37.5%. However, it is unclear whether there is reduction of LAR after 21 postoperative days without defunctioning stoma bu... | ['Anastomosis, Surgical', 'Anastomotic Leak', 'Animals', 'Fibrin Tissue Adhesive', 'Models, Animal', 'Rectum', 'Surgical Stapling', 'Swine'] | 31,056,009 | [['E04.035'], ['C23.550.767.071'], ['B01.050'], ['D12.776.124.270.305'], ['E05.598'], ['A03.556.124.526.767', 'A03.556.249.249.767'], ['E04.987.775.800'], ['B01.050.150.900.649.313.500.880']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Manganese superoxide dismutase protects mitochondrial complex I against adriamycin-induced cardiomyopathy in transgenic mice. | Adriamycin (ADR) is a potent anticancer drug that causes severe cardiomyopathy. We have previously demonstrated that ADR-induced ultrastructural mitochondrial injury in the heart was attenuated in manganese superoxide dismutase (MnSOD) transgenic mice. To further investigate the biochemical mechanisms by which MnSOD pr... | ['Animals', 'Cardiomyopathies', 'Creatine Kinase', 'Doxorubicin', 'Electron Transport', 'Enzyme Activation', 'Mice', 'Mice, Inbred C3H', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Mitochondria, Heart', 'Myocardium', 'NAD(P)H Dehydrogenase (Quinone)', 'Oxygen Consumption', 'Superoxide Dismutase'] | 9,917,329 | [['B01.050'], ['C14.280.238'], ['D08.811.913.696.640.150'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['G02.111.263', 'G03.328'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.388', 'B01.050.... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Optic Radiation Diffusion Tensor Imaging Tractography: An Alternative and Simple Technique for the Accurate Detection of Meyer's Loop. | BACKGROUND: The optic radiation (OR) is a white matter bundle with a very complex anatomy. Its anterior component bends sharply around the tip of the temporal horn, forming the Meyer's loop (ML), the sparing of which during surgery is crucial to preserve visual function. Defining its exact anatomy and accurately identi... | ['Adult', 'Aged', 'Brain Diseases', 'Brain Mapping', 'Diffusion Tensor Imaging', 'Female', 'Geniculate Bodies', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Nerve Fibers', 'Neurosurgical Procedures', 'Organ Sparing Treatments', 'Temporal Lobe', 'Treatment Outcome', 'Visual Pathways', 'White Matter'] | 29,857,218 | [['M01.060.116'], ['M01.060.116.100'], ['C10.228.140'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E01.370.350.578.750', 'E01.370.350.825.500.150.500', 'E01.370.376.537.500', 'E05.629.750'], ['A08.186.211.200.317.826.701.444'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Silent aortic insufficiency mimicking dilated cardiomyopathy]. | The authors report 6 cases of severe and silent aortic insufficiency having simulated in all aspects the picture of a dilated cardiomyopathy at the stage of cardiac insufficiency with primary manifestations. They insist on signs leading to the diagnosis of this clinical entity: past history of rheumatism, signs of elec... | ['Aortic Valve Insufficiency', 'Cardiomyopathy, Dilated', 'Diagnosis, Differential', 'Humans', 'Male', 'Middle Aged'] | 3,592,558 | [['C14.280.484.048.500'], ['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Determination of dengue virus serotypes in Thailand using PCR based method. | A reverse transcriptase-polymerase chain reaction (RT-PCR) and a single-tube multiplex PCR assay was modified for typing of dengue virus in different geographical areas of Thailand during 2000-2001. A set of primers (D1 and D2) was used to generate the RT-PCR product of 511 bp in size which subsequently underwent a sin... | ['DNA Primers', 'Dengue', 'Dengue Virus', 'Humans', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sensitivity and Specificity', 'Seroepidemiologic Studies', 'Serotyping', 'Thailand'] | 15,115,087 | [['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['C01.920.500.270', 'C01.925.081.270', 'C01.925.782.350.250.214', 'C01.925.782.417.214'], ['B04.820.578.344.350.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.620.500.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Atypical cilia in testicular cells from normal rats. | During our observations solitary cilia have been noted in Sertoli cells, fibroblasts and myoid cells of the rat testes. They mostly presented a 9 + 0 pattern and appeared similar to those previously reported in other cell types. In the present report, we describe their structure and analyze their putative functional si... | ['Animals', 'Cilia', 'Male', 'Rats', 'Rats, Wistar', 'Sertoli Cells', 'Testis'] | 9,267,039 | [['B01.050'], ['A11.284.180.165'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['A05.360.444.849.789', 'A11.382.952', 'A11.436.837'], ['A05.360.444.849', 'A05.360.576.782', 'A06.300.312.782']] | ['Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Negative confounding by essential fatty acids in methylmercury neurotoxicity associations. | BACKGROUND: Methylmercury, a worldwide contaminant of fish and seafood, can cause adverse effects on the developing nervous system. However, long-chain n-3 polyunsaturated fatty acids in seafood provide beneficial effects on brain development. Negative confounding will likely result in underestimation of both mercury t... | ['Attention', 'Child', 'Cohort Studies', 'Denmark', 'Fatty Acids, Essential', 'Fatty Acids, Omega-3', 'Female', 'Fetal Blood', 'Food Contamination', 'Humans', 'Infant, Newborn', 'Male', 'Mental Recall', 'Methylmercury Compounds', 'Neuropsychological Tests', 'Neurotoxins', 'Pregnancy', 'Prenatal Exposure Delayed Effects... | 24,561,639 | [['F02.830.104.214'], ['M01.060.406'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['Z01.542.816.124'], ['D10.251.355.310'], ['D10.212.302.380.410', 'D10.251.355.337', 'D10.627.430.450'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['J01.576.423.850.730.500.249', 'N06.850.460.4... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
The structure of variation and its influence on the estimation of status: indicators of condition of lakes in the Northeast, U.S.A. | One goal of regional-scale sample surveys is to estimate the status of a resource of interest from a statistically drawn representative sample of that resource. An expression of status is the frequency distribution of indicator scores capturing variability of attributes of interest. However, extraneous variability inte... | ['Analysis of Variance', 'Animals', 'Biodiversity', 'Crustacea', 'Environmental Monitoring', 'Fishes', 'Fresh Water', 'Linear Models', 'New England', 'Population Dynamics', 'Zooplankton'] | 15,473,526 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G16.500.275.157.049', 'N06.230.124.049'], ['B01.050.500.131.365'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.493'], ['G16.500.275.280', 'N06.230.232'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Synthesis and structural characterization of mixed-metal complexes of Cu(I) with MOS3 cores (M = Mo, W) and of an unusual polymeric AgI/mercaptoimidazole complex with five different Ag(I) coordination environments. | Reaction of (NH(4))(2)[MO(2)S(2)] (M = Mo or W) with KI, CuCl and 1,3-diazepane-2-thione (Diap) in acetone affords air- and moisture-stable mixed-metal cluster compounds [MOS(3)(CuDiap)(3)]I (1 and 2). Attempts to produce [WS(4)Ag(2)(Mim(Ph))(4)] (Mim(Ph) = 2-mercapto-1-phenylimidazole) led to the unexpected polymeric ... | ['Coordination Complexes', 'Copper', 'Crystallography, X-Ray', 'Hydrogen Bonding', 'Imidazoles', 'Molecular Conformation', 'Molybdenum', 'Polymers', 'Silver', 'Tungsten'] | 21,301,738 | [['D01.234', 'D02.257'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['E05.196.309.742.225'], ['G02.282'], ['D03.383.129.308'], ['G02.111.570.820'], ['D01.268.556.555', 'D01.268.956.500', 'D01.552.544.555'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.81... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The effect of hyperbaric oxygen on intraocular pressure. | The effects of hyperoxia on intraocular pressure (IOP) have been studied in experiments on human beings and animals. The changes occurring in IOP in patients during routine HBO2 therapy are unknown. In this study we investigated IOP changes arising during the HBO2 therapy at 2.5 ATA. Fifty-six patients receiving HBO2 t... | ['Adult', 'Analysis of Variance', 'Female', 'Humans', 'Hyperbaric Oxygenation', 'Intraocular Pressure', 'Male', 'Middle Aged', 'Partial Pressure'] | 16,602,250 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.880.690.490'], ['G14.440'], ['M01.060.116.630'], ['G01.374.715.714']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Expression and diagnosis value of Fascin in non-small cell lung cancer patients]. | OBJECTIVE: To evaluate the diagnostic significance of Fascin protein in non-small cell lung cancer (NSCLC) patients.METHODS: Among 110 cases of NSCLC patients and 50 cases of healthy controls, double antibody sandwich enzyme-linked immunosorbent assay (ELISA) was employed to measure the serum levels of Fascin protein, ... | ['Adult', 'Aged', 'Biomarkers, Tumor', 'Carcinoma, Non-Small-Cell Lung', 'Carrier Proteins', 'Case-Control Studies', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Microfilament Proteins', 'Middle Aged'] | 24,300,277 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['D12.776.157'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Localization of bovine liver aldehyde dehydrogenase isozymes and their immunological properties. | Evidence supporting the existence of three aldehyde dehydrogenases in bovine liver has been confirmed and the immunological properties of these isozymes have been compared. 1. The cytoplasmic and mitochondrial aldehyde dehydrogenases were distinguished in size by subjecting the bovine liver crude extract to Sephadex G-... | ['Acetaldehyde', 'Aldehyde Dehydrogenase', 'Aldehyde Oxidoreductases', 'Animals', 'Cattle', 'Cytoplasm', 'Immunodiffusion', 'Isoenzymes', 'Liver', 'Microsomes, Liver', 'Molecular Weight', 'Submitochondrial Particles'] | 6,788,756 | [['D02.047.064'], ['D08.811.682.657.163.249'], ['D08.811.682.657.163'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.284.430.214'], ['E01.370.225.812.735.645.350', 'E05.200.812.735.645.350', 'E05.478.594.760.645.350', 'E05.478.605.492.350'], ['D08.811.348', 'D12.776.800.300'], ['A03.620'], ['A11.284.835.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Physiological and behavioral responses in offspring mice following maternal exposure to sulfamonomethoxine during pregnancy. | Sulfamonomethoxine (SMM), a veterinary antibiotic, is widely used in China. However, the impacts of maternal SMM exposure on neurobehavioral development in early life remain little known. In this study, we investigated the effects of maternal SMM exposure during pregnancy on behavioral and physiological responses in of... | ['Animals', 'Anti-Infective Agents', 'Anxiety', 'Behavior, Animal', 'Blood Glucose', 'Body Weight', 'Brain-Derived Neurotrophic Factor', 'Female', 'Male', 'Maternal Exposure', 'Maze Learning', 'Mice', 'Mice, Inbred ICR', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Serotonin', 'Sulfamonomethoxine', 'Thyroxine', '... | 27,173,165 | [['B01.050'], ['D27.505.954.122'], ['F01.470.132'], ['F01.145.113'], ['D09.947.875.359.448.500'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['N06.850.460.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
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