Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Using cavity theory to describe the dependence on detector density of dosimeter response in non-equilibrium small fields. | The dose imparted by a small non-equilibrium photon radiation field to the sensitive volume of a detector located within a water phantom depends on the density of the sensitive volume. Here this effect is explained using cavity theory, and analysed using Monte Carlo data calculated for schematically modelled diamond an... | ['Monte Carlo Method', 'Phantoms, Imaging', 'Photons', 'Radiation Dosage', 'Radiometry', 'Water'] | 23,574,749 | [['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['E07.671'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['E05.799'], ['D01.045.250.875', 'D01.248.497.158.459.650', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Simple and sensitive aptasensor based on quantum dot-coated silica nanospheres and the gold screen-printed electrode. | A novel electrochemical aptasensor involving quantum dots-coated silica nanospheres (QDs/Si) and the screen-printed gold electrodes (SPGE) was developed for the detection of thrombin. The screen-printed electrodes with several advantages, including low cost, versatility, miniaturization, and mechanical regeneration aft... | ['Aptamers, Nucleotide', 'Base Sequence', 'Biosensing Techniques', 'Dielectric Spectroscopy', 'Electrochemistry', 'Electrodes', 'Enzymes, Immobilized', 'Gold', 'Humans', 'Nanoparticles', 'Printing', 'Quantum Dots', 'Silicon Dioxide', 'Surface Properties', 'Thrombin'] | 22,967,605 | [['D13.695.578.424.224'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.601.043'], ['E05.196.867.335'], ['H01.181.529.307'], ['E07.305.250'], ['D08.811.180', 'D12.776.463.500'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.637.512.6... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Trends in Operating Room Assistance for Major Urologic Surgical Procedures: An Increasing Role for Advanced Practice Providers. | OBJECTIVE: To characterize changes in surgical assistance patterns over time for commonly performed urologic operations.MATERIALS AND METHODS: This study used the Medicare Physician/Supplier Procedure Summary Master File to identify cases performed by urologists from 2003 to 2014. Current Procedural Terminology modifie... | ['Humans', 'Operating Rooms', 'Physician Assistants', 'Professional Role', 'Retrospective Studies', 'United States', 'Urologic Surgical Procedures', 'Urologists', 'Workforce', 'Workload'] | 28,499,759 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.700'], ['M01.526.485.067.740', 'N02.360.067.740'], ['F01.829.316.616.625'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ... | ['Organisms [B]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Increased motor drive and sleep loss in mice lacking Kv3-type potassium channels. | The voltage-gated potassium channels Kv3.1 and Kv3.3 are widely expressed in the brain, including areas implicated in the control of motor activity and in areas thought to regulate arousal states. Although Kv3.1 and Kv3.3-single mutants show some physiological changes, previous studies revealed relatively subtle behavi... | ['Animals', 'Behavior, Animal', 'Heterozygote', 'Homozygote', 'Hyperkinesis', 'Male', 'Mice', 'Mice, Knockout', 'Motor Activity', 'Myoclonus', 'Neuropeptides', 'Potassium Channels', 'Potassium Channels, Voltage-Gated', 'Shaw Potassium Channels', 'Sleep', 'Stereotyped Behavior'] | 15,005,717 | [['B01.050'], ['F01.145.113'], ['G05.380.383'], ['G05.380.554'], ['C10.597.350.350', 'C23.888.592.350.350'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.313.992.635.505.500.800.500'], ['F01.145.632', 'G11.427.410.698'],... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Low dosages of exogenous growth hormone and its effect on growth in an animal model of suboptimal nutrition. | In a previous study, weight gain, insulin growth factor-1 (IGF-1) and insulin growth factor binding protein-3 (IGFBP-3) were increased in rats fed suboptimal levels of energy and administered 0.1 mg/100 g of body weight of recombinant human growth hormone (rhGH). Our objective was to determine whether these anabolic ef... | ['Animals', 'Energy Metabolism', 'Food Deprivation', 'Growth Hormone', 'Insulin-Like Growth Factor Binding Protein 3', 'Insulin-Like Growth Factor I', 'Male', 'Models, Animal', 'Rats', 'Rats, Sprague-Dawley', 'Weight Gain'] | 11,118,828 | [['B01.050'], ['G03.295'], ['F01.658.433'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['D12.776.157.420.270'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['E05.598'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development and Psychometric Evaluation of Health Protective Sexual Communication Content Discussed Scale for Young Women in Gaborone, Botswana. | Health protective sexual communication can reduce HIV transmission, but women in Botswana find it difficult because of cultural barriers, suggesting the need for relevant measures. A Health Protective Sexual Communication Content Discussed Scale was developed and tested among young women aged 21-35 years in Gaborone, B... | ['Adult', 'Botswana', 'Female', 'Humans', 'Psychometrics', 'Reproducibility of Results', 'Risk Reduction Behavior', 'Sex Education', 'Sexually Transmitted Diseases', 'Surveys and Questionnaires', "Women's Health", 'Young Adult'] | 28,714,446 | [['M01.060.116'], ['Z01.058.290.175.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['F01.145.699'], ['F04.096.837.500', 'I02.233.332.749'], ['C01.221.812', 'C01.778', 'C12.294.668', 'C13.351.500.711', 'C23.550.29... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The control of confounding by intermediate variables. | In epidemiologic studies of the effect of an exposure on disease, the crude association of exposure with disease may fail to reflect a causal association due to confounding by one or more covariates. Most previous discussions of confounding in the epidemiologic literature have considered only point exposure studies, th... | ['Data Interpretation, Statistical', 'Epidemiologic Methods', 'Epidemiology', 'Humans', 'Longitudinal Studies', 'Mathematics', 'Models, Statistical', 'Random Allocation', 'Risk Factors'] | 2,749,074 | [['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['E05.318', 'N06.850.520'], ['H02.403.720.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['H01.548'], ['E05.31... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Direct computation of long time processes in peptides and proteins: reaction path study of the coil-to-helix transition in polyalanine. | The MaxFlux reaction path algorithm was used to isolate optimal transition pathways for the coil-to-helix transition in polyalanine. Eighteen transition pathways, each connecting one random coil configuration with an ideal alpha-helical configuration, were computed and analyzed. The transition pathway energetics and me... | ['Algorithms', 'Computer Simulation', 'Hydrogen Bonding', 'Kinetics', 'Models, Molecular', 'Peptides', 'Protein Denaturation', 'Protein Folding', 'Protein Structure, Secondary', 'Proteins', 'Solvents', 'Temperature', 'Thermodynamics', 'Water'] | 10,398,371 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['G02.282'], ['G01.374.661', 'G02.111.490'], ['E05.599.595'], ['D12.644'], ['G01.154.651.750.500', 'G02.111.688.750.500'], ['G01.154.651', 'G02.111.688'], ['G02.111.570.820.709.600'], ['D12.776'], ['D27.720.844'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
CM-Pf deep brain stimulation and the long term management of motor and psychiatric symptoms in a case of Tourette syndrome. | Tourette syndrome is a rare neuropsychiatric disorder affecting the cortico-striato-thalamo-cortical system. The disease manifests in childhood with tics and various psychiatric comorbidities. Cases of refractory Tourette syndrome are valuable candidates for functional neurosurgery. The thalamic centromedian-parafascic... | ['Adult', 'Deep Brain Stimulation', 'Humans', 'Male', 'Thalamus', 'Tourette Syndrome'] | 30,612,913 | [['M01.060.116'], ['E02.331.300', 'E04.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.186.211.200.317.826'], ['C10.228.140.079.898', 'C10.228.662.825.800', 'C10.574.500.850', 'C16.320.400.820', 'F03.625.992.850']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identification and characterization of antigenic determinants of Mycobacterium leprae that react with antibodies in sera of leprosy patients. | Antigenic determinants of Mycobacterium leprae were identified by screening a lambda gt11::M. leprae genomic library with two separate pools of sera from leprosy patients. A total of 45 recombinant clones were detected with pooled sera from 21 lepromatous (LL) leprosy patients and 5 additional clones specified polypept... | ['Antibodies, Bacterial', 'Antigens, Bacterial', 'Bacterial Proteins', 'Blotting, Western', 'Cloning, Molecular', 'Epitopes', 'Gene Library', 'Humans', 'Leprosy', 'Mycobacterium leprae'] | 1,691,143 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D23.050.161'], ['D12.776.097'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.393.220'], ['D23.050.550'], ['G05.360.325'], ['B01.050.150.900.649.313.988.400.112.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of flow for the deposition of platelets. | Implants inside the cardiovascular system are subjected to blood flow. Platelet deposition usually takes place, eventually leading to thrombus formation. Tests must be performed in order to select a suitable biomaterial, but no generally accepted test method exists for biomaterials in contact with blood. At a first gla... | ['Blood Platelets', 'Cell Adhesion', 'Hemorheology', 'Thrombosis'] | 26,984,235 | [['A11.118.188', 'A15.145.229.188'], ['G04.022'], ['E05.830.250', 'G09.188.370', 'G09.330.380.630'], ['C14.907.355.830']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biphasic pattern of bacterial infection in multiple myeloma. | Since the 1960s, gram-negative bacilli have become commoner pathogens than Streptococcus pneumoniae in multiple myeloma. To investigate this trend, we analyzed 75 bacterial infections in 57 patients with myeloma. Episodes of infection with Streptococcus pneumoniae and Haemophilus influenzae occurred at presentation, ea... | ['Aged', 'Bacterial Infections', 'Female', 'Haemophilus Infections', 'Haemophilus influenzae', 'Humans', 'Immunoglobulins', 'Leukocyte Count', 'Male', 'Multiple Myeloma', 'Neutrophils', 'Pneumococcal Infections', 'Retrospective Studies', 'Staphylococcal Infections', 'Staphylococcus aureus', 'Streptococcus pneumoniae'] | 6,976,144 | [['M01.060.116.100'], ['C01.150.252'], ['C01.150.252.400.700.433'], ['B03.440.450.600.450.330', 'B03.660.250.550.290.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485', 'D12.776.124.790.651', 'D12.776.377.715.548'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Site-specific programming of the host epithelial transcriptome by the gut microbiota. | BACKGROUND: The intestinal epithelium separates us from the microbiota but also interacts with it and thus affects host immune status and physiology. Previous studies investigated microbiota-induced responses in the gut using intact tissues or unfractionated epithelial cells, thereby limiting conclusions about regional... | ['Animals', 'Epithelial Cells', 'Gastrointestinal Microbiome', 'Gastrointestinal Tract', 'Gene Expression Regulation', 'Immune System', 'Mice', 'Microarray Analysis', 'Microbiota', 'Signal Transduction', 'Transcriptome'] | 25,887,251 | [['B01.050'], ['A11.436'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['A03.556'], ['G05.308'], ['A15.382'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.588.570'], ['G06.591', 'G16.500.275.157.049.100.500', 'N06.230.124.049.100.500'], ['G02.111.820', 'G04.835'], ['G02.111.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Route learning and shortcut performance in adults with intellectual disability: a study with virtual environments. | The ability to learn routes though a virtual environment (VE) and to make a novel shortcut between two locations was assessed in 18 adults with intellectual disability and 18 adults without intellectual disability matched on chronological age. Participants explored two routes (A ? B and A ? C) until they reached a lear... | ['Adult', 'Computer-Assisted Instruction', 'Cues', 'Education of Intellectually Disabled', 'Environment', 'Female', 'Humans', 'Intellectual Disability', 'Male', 'Maze Learning', 'Space Perception', 'User-Computer Interface'] | 21,084,172 | [['M01.060.116'], ['I02.903.771.500.208'], ['F02.463.425.234'], ['F02.784.629.375', 'I02.233.213.400'], ['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['F02.463.425.874.500'], ['F02.463.593.778'], ['L01.224.900.910']... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Continuous peritoneal dialysis compared with daily hemodialysis in patients with acute kidney injury. | BACKGROUND: In some parts of the world, peritoneal dialysis is widely used for renal replacement therapy (RRT) in acute kidney injury (AKI), despite concerns about its inadequacy. It has been replaced in recent years by hemodialysis and, most recently, by continuous venovenous therapies. We performed a prospective stud... | ['Acid-Base Equilibrium', 'Acute Kidney Injury', 'Aged', 'Blood Urea Nitrogen', 'Brazil', 'Creatinine', 'Female', 'Follow-Up Studies', 'Glomerular Filtration Rate', 'Humans', 'Male', 'Middle Aged', 'Peritoneal Dialysis, Continuous Ambulatory', 'Renal Dialysis', 'Retrospective Studies', 'Time Factors', 'Treatment Outcom... | 19,270,234 | [['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116.100'], ['E01.370.225.124.100.115', 'E01.370.390.400.100', 'E05.200.124.100.115'], ['Z01.107.757.176'], ['D03.383.129.308.207'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Alcohol modulation of cloned GABAA receptor-channel complex expressed in human kidney cell lines. | The effects of n-octanol on GABA-induced currents were examined on the alpha 1 beta 2 gamma 2s and alpha 1 beta 2 combinations of GABAA receptor subunits expressed in a human kidney cell line (HEK 293), using the whole-cell variation of the patch clamp technique. The EC50 of the GABA dose-response curve for the alpha 1... | ['1-Octanol', 'Cell Line', 'Chlordiazepoxide', 'Cloning, Molecular', 'Dose-Response Relationship, Drug', 'Electrophysiology', 'Humans', 'Ion Channels', 'Kidney', 'Octanols', 'Receptors, GABA', 'gamma-Aminobutyric Acid'] | 7,507,787 | [['D02.033.415.600.600', 'D10.289.600.610'], ['A11.251.210'], ['D03.633.100.079.080.150'], ['E05.393.220'], ['G07.690.773.875', 'G07.690.936.500'], ['H01.158.344.528', 'H01.158.782.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['A05.810.45... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Cleavage at Arg-1689 influences heavy chain cleavages during thrombin-catalyzed activation of factor VIII. | The procofactor, factor VIII, is activated by thrombin or factor Xa-catalyzed cleavage at three P1 residues: Arg-372, Arg-740, and Arg-1689. The catalytic efficiency for thrombin cleavage at Arg-740 is greater than at either Arg-1689 or Arg-372 and influences reaction rates at these sites. Because cleavage at Arg-372 a... | ['Arginine', 'Catalysis', 'Enzyme-Linked Immunosorbent Assay', 'Factor VIII', 'Factor Xa', 'Humans', 'Kinetics', 'Mutation', 'Protein Binding', 'Protein Structure, Tertiary', 'Recombinant Proteins', 'Thrombin', 'Time Factors'] | 19,240,027 | [['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G02.130'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D12.776.124.125.350', 'D12.776.811.286', 'D23.119.350'], ['D08.811.277.656.300.760.315', 'D08.811.277.656.959.350.315', 'D12.776... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
RNA-transfected CD40-activated B cells induce functional T-cell responses against viral and tumor antigen targets: implications for pediatric immunotherapy. | Vaccination with antigen-presenting cells (APCs) engineered to mimic mechanisms of immune stimulation represents a promising approach for cancer immunotherapy. Dendritic cell vaccines have entered phase 3 testing in adult malignancies, but such vaccines in children have been limited. We demonstrate that CD40-activated ... | ['Adult', 'Age Factors', 'Animals', 'Antigens, Neoplasm', 'Antigens, Viral', 'B-Lymphocytes', 'CD40 Antigens', 'Cancer Vaccines', 'Child', 'Electroporation', 'Humans', 'Immunotherapy', 'In Vitro Techniques', 'Influenza, Human', 'Lymphocyte Activation', 'MART-1 Antigen', 'Mice', 'NIH 3T3 Cells', 'Neoplasm Proteins', 'RN... | 14,630,810 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['D23.050.285'], ['D23.050.327'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D12.776.465.750', 'D12.776.543.750.705.852.760.097', 'D23.050.301.264.051.140', 'D23.101.100... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Morphological aspects of the kidney: can normality be predicted? | PURPOSE: Our study aimed to assess the normal parameters of renal parenchyma and upper urinary tract from a contrast enhanced computed tomography assessment in order to create a mathematical model of normal kidney.PATIENTS AND METHODS: We conducted a retrospective observation study on 520 patients with a normal abdomin... | ['Adult', 'Aged', 'Aged, 80 and over', 'Body Height', 'Body Mass Index', 'Female', 'Humans', 'Kidney', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Organ Size', 'Radiography', 'Young Adult'] | 22,203,941 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Use of hemodialysis in intensive care of organophosphorus insecticide poisoning]. | A total of 163 hemoperfusions carried out in order to remove poison in patients with acute poisoning with organophosphorous insecticides (OPI) showed that this treatment modality effectively removes OPI from te organism. In patients with the most severe forms of acute poisoning hemoperfusion may be effectively combined... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Critical Care', 'Hemoperfusion', 'Humans', 'Insecticides', 'Middle Aged', 'Organophosphorus Compounds', 'Peritoneal Dialysis', 'Renal Dialysis', 'Sorption Detoxification'] | 9,173,829 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.760.190', 'N02.421.585.190'], ['E02.870.244', 'E02.912.430', 'E04.292.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.031.700.491', 'D27.888.723.491'], ['M01.060.116.630'], ['D02.705'], ['E02.870.300.650', 'E02.912.800.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Five year long term results of total joint arthroplasties in the treatment of trapeziometacarpal osteoarthritis. | INTRODUCTION: Trapeziometacarpal (TMC) osteoarthritis is a common disease. Patients with advanced disease who have failed conservative treatment have different surgical options, including total joint prosthesis. The aim of this study was to investigate the long-term outcome and complications of trapeziometacarpal (TMC)... | ['Aged', 'Arthroplasty, Replacement', 'Carpometacarpal Joints', 'Female', 'Humans', 'Male', 'Middle Aged', 'Osteoarthritis', 'Postoperative Complications', 'Retrospective Studies', 'Time Factors', 'Trapezium Bone', 'Treatment Outcome'] | 31,910,169 | [['M01.060.116.100'], ['E04.555.110.110', 'E04.650.110', 'E04.680.101.110'], ['A02.835.583.405.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.550.114.606', 'C05.799.613'], ['C23.550.767'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Serial micropuncture analysis of glomerular function in two rat models of glomerular sclerosis. | We have recently developed a micropuncture technique to assess repeatedly function of the same nephrons in chronic renal disease and subsequently examine the morphology of their glomeruli by serial thin-section histological analysis. Using this approach, a potential causal linkage between early functional patterns and ... | ['Animals', 'Blood Pressure', 'Blood Urea Nitrogen', 'Body Weight', 'Chronic Disease', 'Disease Models, Animal', 'Doxorubicin', 'Glomerular Filtration Rate', 'Glomerulonephritis', 'Glomerulosclerosis, Focal Segmental', 'Kidney Glomerulus', 'Microsurgery', 'Proteinuria', 'Punctures', 'Puromycin Aminonucleoside', 'Rats',... | 3,392,211 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.225.124.100.115', 'E01.370.390.400.100', 'E05.200.124.100.115'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C23.550.291.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of the PAR4 thrombin receptor in stabilizing platelet-platelet aggregates as revealed by a patient with Hermansky-Pudlak syndrome. | Individuals with Hermansky-Pudlak Syndrome (HPS) lack platelet dense granules and have no ADP-autocrine response. Despite these platelet deficiencies, HPS patients exhibit a surprisingly mild bleeding phenotype. We hypothesize that activation of the PAR4 thrombin receptor compensates for the lack of an ADP-autocrine re... | ['Adenosine Monophosphate', 'Adult', 'Amino Acid Sequence', 'Antibodies, Monoclonal', 'Female', 'Hermanski-Pudlak Syndrome', 'Humans', 'Membrane Proteins', 'Models, Biological', 'Molecular Sequence Data', 'Oligopeptides', 'Peptide Fragments', 'Platelet Aggregation', 'Puerto Rico', 'Purinergic P2 Receptor Antagonists', ... | 12,008,957 | [['D03.633.100.759.646.138.180', 'D13.695.667.138.180', 'D13.695.827.068.180'], ['M01.060.116'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C11.270.040.545.400', 'C15.378.100.100.515', 'C15.378.100.685.400', 'C15.378.140.7... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Analysis of the ribosome large subunit assembly and 23 S rRNA stability in vivo. | The ability of mutant 23 S ribosomal RNA to form particles with proteins of the large ribosomal subunit in vivo was studied. A series of overlapping deletions covering the entire 23 S rRNA, were constructed in the plasmid copy of an E. coli 23 S rRNA gene. The mutant genes were expressed in vivo using an inducible tac ... | ['Binding Sites', 'Escherichia coli', 'RNA, Ribosomal, 16S', 'RNA, Ribosomal, 23S', 'Ribosomal Proteins', 'Ribosomes', 'Sequence Deletion'] | 8,918,596 | [['G02.111.570.120'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D13.444.735.686.670'], ['D13.444.735.686.680'], ['D12.776.835'], ['A11.284.430.214.190.875.811'], ['G05.365.590.762', 'G05.558.800']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dietary trans and saturated fatty acids effects on semen quality, hormonal levels and expression of genes related to steroid metabolism in mouse adipose tissue. | Our objectives were to assess sperm alteration and adipose tissue (AT) genes expression related to steroid metabolism subsequent to fatty acids consumption. Twenty-nine mature male mice were divided into: fat diet (FD; n = 15) and the control group (n = 14). FD group was fed with low level of trans and saturated fatty ... | ['Adipose Tissue', 'Androgens', 'Animals', 'Diet, High-Fat', 'Dietary Fats', 'Estrogens', 'Fatty Acids', 'Male', 'Mice', 'Models, Animal', 'Sperm Count', 'Steroids'] | 30,873,638 | [['A10.165.114'], ['D27.505.696.399.472.161'], ['B01.050'], ['G07.203.650.240.267'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D27.505.696.399.472.277'], ['D10.251'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.598'], ['E01.370.225.500.195.870', 'E01.370.225.992.624', 'E05.200.500.195.870', 'E05.200.9... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Evaluation of the relative cost-effectiveness of treatments for infertility in the UK. | This paper aims to complement existing clinical guidelines by providing evidence of the relative cost-effectiveness of treatments for infertility in the UK. A series of decision-analytical models have been developed to reflect current diagnostic and treatment pathways for the five main causes of infertility. Data to po... | ['Cost-Benefit Analysis', 'Diathermy', 'Fallopian Tube Diseases', 'Female', 'Fertilization in Vitro', 'Humans', 'Infertility', 'Insemination, Artificial', 'Laparoscopy', 'Male', 'Models, Biological', 'Models, Statistical', 'Ovulation', 'Polycystic Ovary Syndrome', 'Pregnancy', 'Reproductive Techniques', 'Sperm Injectio... | 10,611,196 | [['N03.219.151.125'], ['E02.565.280'], ['C13.351.500.056.390'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365', 'C13.351.500.365'], ['E02.875.800.937', 'E05.820.800.937', 'G08.686.784.363.492'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E05.599.395'], ['E05.3... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Plasma zinc, copper, selenium, ferritin and whole blood manganese concentrations in children with kwashiorkor in the acute stage and during refeeding. | Plasma zinc, copper, selenium, ferritin and whole blood manganese concentrations were measured in 22 children with kwashiorkor on admission to hospital and on days 5, 10 and 30 of refeeding. Twenty similarly aged, healthy, well nourished children served as controls. The mean (SEM) zinc, copper and selenium concentratio... | ['Acute Disease', 'Body Weight', 'Ceruloplasmin', 'Child, Preschool', 'Copper', 'Ferritins', 'Humans', 'Infant', 'Kwashiorkor', 'Manganese', 'Selenium', 'Zinc'] | 1,376,581 | [['C23.550.291.125'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D08.811.682.226', 'D12.776.124.050.130', 'D12.776.124.790.106.214', 'D12.776.157.160', 'D12.776.377.715.085.214', 'D12.776.556.151'], ['M01.060.406.448'], ['D01.268.556.195', 'D01... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Impact of achieved blood pressures on mortality risk and end-stage renal disease among a large, diverse hypertension population. | BACKGROUND: Medical data or clinical guidelines have not adequately addressed the ideal blood pressure (BP) treatment targets for survival and renal outcome.OBJECTIVES: This study sought to evaluate ranges of treated BP in a large hypertension population and compare risk of mortality and end-stage renal disease (ESRD).... | ['Aged', 'Blood Pressure', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Humans', 'Hypertension', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Population Surveillance', 'Retrospective Studies', 'Risk Factors', 'Survival Rate'] | 25,104,529 | [['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C12.777.419.780.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gender differences in endothelial progenitor cells and cardiovascular risk profile: the role of female estrogens. | OBJECTIVE: Endothelial progenitor cells (EPCs) participate in vascular homeostasis and angiogenesis. The aim of the present study was to explore EPC number and function in relation to cardiovascular risk, gender, and reproductive state.METHODS AND RESULTS: As measured by flow-cytometry in 210 healthy subjects, CD34(+)K... | ['Adult', 'Aged', 'Animals', 'Ataxin-1', 'Ataxins', 'Cardiovascular Diseases', 'Cell Adhesion', 'Cell Proliferation', 'Cells, Cultured', 'Endothelium, Vascular', 'Estradiol', 'Estrogens', 'Female', 'Homeostasis', 'Humans', 'Infant, Newborn', 'Male', 'Menstrual Cycle', 'Mesenchymal Stem Cells', 'Middle Aged', 'Neovascul... | 18,276,910 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['D12.776.631.069.500', 'D12.776.660.075.500'], ['D12.776.631.069', 'D12.776.660.075'], ['C14'], ['G04.022'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['A07.015.700.500', 'A10.272.491.355'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D27.505... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Manipulation Under Anesthesia as a Treatment of Posttraumatic Elbow Stiffness. | OBJECTIVES: Evaluate the safety and efficacy of manipulation under anesthesia (MUA) for posttraumatic elbow stiffness.DESIGN: Retrospective, case series.SETTING: Single institution; level 1 trauma center.PATIENTS/PARTICIPANTS: Chart review of 45 patients over a 10-year period treated with MUA for posttraumatic elbow st... | ['Adolescent', 'Adult', 'Aged', 'Anesthesia', 'Contracture', 'Elbow Joint', 'Female', 'Follow-Up Studies', 'Forecasting', 'Humans', 'Joint Diseases', 'Male', 'Middle Aged', 'Musculoskeletal Manipulations', 'Range of Motion, Articular', 'Recovery of Function', 'Retrospective Studies', 'Treatment Outcome', 'Young Adult'] | 30,028,796 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E03.155'], ['C05.550.323', 'C05.651.197'], ['A02.835.583.290'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550'], ['M01.060.116.630'], ['E02.190.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Helix-capping interaction in lambda Cro protein: a free energy simulation analysis. | The stability mutant Tyr-26-->Asp was studied in the Cro protein from bacteriophage lambda using free energy molecular dynamics simulations. The mutant was calculated to be more stable than the wild type by 3.0 +/- 1.7 kcal/mol/monomer, in reasonable agreement with experiment (1.4 kcal/mol/monomer). Moreover, the aspar... | ['Aspartic Acid', 'Bacteriophage lambda', 'Computer Simulation', 'DNA-Binding Proteins', 'Hydrogen Bonding', 'Models, Molecular', 'Mutation', 'Protein Structure, Secondary', 'Repressor Proteins', 'Thermodynamics', 'Tyrosine', 'Viral Proteins', 'Viral Regulatory and Accessory Proteins', 'Water'] | 7,984,627 | [['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['B04.123.150.800.230', 'B04.123.205.230', 'B04.280.090.800.230'], ['L01.224.160'], ['D12.776.260'], ['G02.282'], ['E05.599.595'], ['G05.365.590'], ['G02.111.570.820.709.600'], ['D12.776.260.703', 'D12.776.930.780'], ['G01.906'], ['D12.125.072.050.875'], ['D12... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Measuring multimorbidity in a working population: the effect on incident sickness absence. | PURPOSE: Multimorbidity research typically focuses on chronic and common diseases in patient and/or older populations. We propose a multidimensional multimorbidity score (MDMS) which incorporates chronic conditions, symptoms, and health behaviors for use in younger, presumably healthier, working populations.METHODS: Cr... | ['Adult', 'Aged', 'Cardiovascular Diseases', 'Chronic Disease', 'Comorbidity', 'Cross-Sectional Studies', 'Fatigue', 'Female', 'Headache', 'Health Behavior', 'Humans', 'Low Back Pain', 'Male', 'Middle Aged', 'Neck Pain', 'Occupational Health', 'Pain', 'Prevalence', 'Sex Factors', 'Sick Leave', 'Sleep Wake Disorders', '... | 26,615,549 | [['M01.060.116'], ['M01.060.116.100'], ['C14'], ['C23.550.291.500'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C23.888.369'], ['C23.888.592.612.441'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.40... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Amadori adducts activate nuclear factor-kappaB-related proinflammatory genes in cultured human peritoneal mesothelial cells. | Diabetes mellitus leads to a high incidence of several so-called complications, sharing similar pathophysiological features in several territories. Previous reports points at early nonenzymatic glycosylation products (Amadori adducts) as mediators of diabetic vascular complications. In the present study, we analysed a ... | ['Blotting, Western', 'Cells, Cultured', 'Cytokines', 'Electrophoretic Mobility Shift Assay', 'Epithelial Cells', 'Epithelium', 'Gene Expression', 'Glycated Hemoglobin A', 'Glycation End Products, Advanced', 'Humans', 'Inflammation', 'Luciferases', 'NF-kappa B', 'Nitric Oxide', 'Nitrites', 'Peritoneum', 'Plasmids', 'Re... | 15,997,235 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['E05.196.401.500'], ['A11.436'], ['A10.272'], ['G05.297'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The antioxidant potential of the New Zealand surf clams. | The antioxidant action of three New Zealand surf clams was evaluated for the first time. Aqueous (cd) and ethanolic extracts from Diamond shell - Crassula aequilatera, Storm shell - Mactra murchisoni, and Tua tua - Paphies donacina were studied for their antioxidant potentials using two in vitro assays. The ethanolic e... | ['Animals', 'Antioxidants', 'Bivalvia', 'New Zealand'] | 26,988,487 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B01.050.500.644.080'], ['Z01.639.760.747', 'Z01.678.100.747']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Infective endocarditis in New Zealand children 1994-2012. | BACKGROUND: New Zealand is a developed country with high incidence of bacterial infections and postinfectious sequelae including rheumatic heart disease. We sought to describe the clinical and microbiology features of children with infective endocarditis (IE) between 1994 and 2012.METHODS: Retrospective review of patie... | ['Adolescent', 'Child', 'Child, Preschool', 'Corynebacterium diphtheriae', 'Endocarditis', 'Female', 'Gram-Positive Bacterial Infections', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'New Zealand', 'Prevalence', 'Risk Factors', 'Staphylococcus aureus', 'Streptococcus pyogenes', 'Survival Analysis'] | 24,378,941 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['B03.510.024.250.150', 'B03.510.460.400.400.200.150'], ['C14.280.282'], ['C01.150.252.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['Z01.639.760.747', 'Z01.678.100.747'], ['E05.318.308.985.525.750', 'N01.224.935.59... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Lipid composition of the plasma membrane isolated from hyperplastic nodules of rat liver. | Hyperplastic nodules and hepatomas were induced in livers of rats fed a diet containing 0.05% N-2-fluorenylacetamide (2-FAA). The lipid contents, and phospholipid and fatty acid compositions were analyzed in plasma membranes (PM's) isolated from these tissues and normal rat liver, and the following trends were observed... | ['Animals', 'Chemical Phenomena', 'Chemistry', 'Cholesterol', 'Fatty Acids', 'Hyperplasia', 'Liver', 'Liver Neoplasms, Experimental', 'Male', 'Membrane Lipids', 'Phospholipids', 'Plasmalogens', 'Rats', 'Rats, Inbred Strains'] | 4,019,434 | [['B01.050'], ['G02'], ['H01.181'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D10.251'], ['C23.550.444'], ['A03.620'], ['C04.588.274.623.460', 'C04.619.540', 'C06.301.623.460', 'C06.552.697.580', 'E05.598.500.496.750'], ['D10.570'], ['D10.570.755'], ['D10.570.755.375.760.400.985.820']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-acting propranolol in the prophylaxis of migraine: a comparative study of two doses. | A randomized double-blind, cross-over study using treatment periods of 12 weeks with a 2-week washout, comparing two long-acting formulations of propranolol ('Inderal' LA 160 mg daily and Half-'Inderal' LA 80 mg daily) was performed after a placebo run-in of 4 weeks on 51 patients. The study indicated that both long-ac... | ['Adolescent', 'Adult', 'Delayed-Action Preparations', 'Double-Blind Method', 'Humans', 'Middle Aged', 'Migraine Disorders', 'Propranolol', 'Randomized Controlled Trials as Topic'] | 2,193,712 | [['M01.060.057'], ['M01.060.116'], ['D26.255.210', 'E02.319.300.253'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.140.546.399.750'], ['D02.033.100.624.698.711', 'D02.033.755.624.698.711', 'D02.092.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Treatment of patients with thermal lesions with ointments on water-soluble base]. | Treatment of patients with thermal burns by ointments prepared on a water-soluble base (Dioxidine and Dioxicol) makes it possible to reduce the bacterial dissemination within a short time and prepare the wound for autodermoplasty which, in turn, reduces the danger of the development of infectious complications. In addi... | ['Adult', 'Anti-Infective Agents', 'Burns', 'Drug Combinations', 'Humans', 'Male', 'Ointment Bases', 'Ointments', 'Polyethylene Glycols', 'Quinoxalines', 'Solubility', 'Trimecaine', 'Uracil', 'Wound Healing'] | 2,214,573 | [['M01.060.116'], ['D27.505.954.122'], ['C26.200'], ['D26.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.650.523', 'D27.720.744.523'], ['D26.255.640'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['D03.633.100.857'], ['G02.805'], ['D02.065.199.092.900', 'D02.092.146.113.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Long-term arthroscopic assessment of intra-articular allografts for treatment of spontaneous cranial cruciate ligament rupture in the dog. | OBJECTIVE: To assess the 12-month survival of intra-articular, decellularized allografts for the treatment of cranial cruciate ligament disease (CCLD) in dogs.STUDY DESIGN: Prospective case series.ANIMALS: Twenty client-owned dogs with spontaneous CCL rupture.METHODS: Affected stifles were treated solely by implantatio... | ['Allografts', 'Animals', 'Anterior Cruciate Ligament', 'Anterior Cruciate Ligament Injuries', 'Arthroscopy', 'Dogs', 'Prospective Studies'] | 31,957,897 | [['A01.941.500'], ['B01.050'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['C26.558.554.213'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650']] | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Differential role of diphenyleneiodonium, a flavoenzyme inhibitor, on p53-dependent and -independent cell cycle progression. | We investigated the differential role of diphenyleneiodonium (DPI), which is widely used as an inhibitor of NADPH oxidase, on the activation of cell cycle regulators in the cell cycle progression. DPI efficiently blocked the transition from G0/G1 to S phase by serum stimulation in quiescent HCT-116 (wild-type p53) and ... | ['Cell Cycle', 'Cell Proliferation', 'Cell Survival', 'Cyclin D1', 'Cyclin-Dependent Kinase Inhibitor p21', 'Dose-Response Relationship, Drug', 'Enzyme Inhibitors', 'Extracellular Signal-Regulated MAP Kinases', 'HCT116 Cells', 'HL-60 Cells', 'Humans', 'NADPH Oxidases', 'Neoplasms', 'Onium Compounds', 'RNA Interference'... | 19,020,764 | [['G04.144'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['D12.644.360.262.150.100', 'D12.776.167.218.150.100', 'D12.776.476.262.150.100', 'D12.776.624.664.700.100'], ['D12.644.360.225.500', 'D12.776.157.687.250', 'D12.776.167.187.500', 'D12.776.476.225.500', 'D12.776.624.776.355.500', 'D12.776.660.720.250'],... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Memisa: surgical help in Cambodia]. | In 1995 the activities of M?decins sans Fronti?res in the Province of Kampot, Cambodia, were handed to Memisa Medicus Mundi. This happened as a part of the co-operation between the two relief agencies. Following a request from the Cambodian Ministry of Health, Memisa sent a Dutch surgeon to Kampot in order to make an i... | ['Adult', 'Cambodia', 'Child', 'Female', 'Femoral Fractures', 'Fracture Fixation', 'Humans', 'Male', 'Netherlands', 'Relief Work', 'Tibial Fractures', 'Traction', 'Traumatology', 'Voluntary Health Agencies', 'Wounds, Gunshot'] | 10,221,125 | [['M01.060.116'], ['Z01.252.145.182'], ['M01.060.406'], ['C26.404.061', 'C26.558.276'], ['E04.555.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.651'], ['I01.880.787.839', 'N06.230.100.300'], ['C26.404.875', 'C26.558.857'], ['E04.555.720'], ['H02.403.810.850'], ['N03.540.630.780'], ['C26.986.900']] | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Rapid and high sensitivity test for direct detection of bovine herpesvirus-1 genome in clinical samples. | A procedure for direct detection of the BHV-1 genome in clinical samples, including semen, was developed. The method is based on the PCR amplification of a highly conserved DNA fragment within the glycoprotein gI sequence of the virus (323 bp between nt 1491 to nt 1814). The method is rapid and highly specific for all ... | ['Animals', 'Base Sequence', 'Cattle', 'Cattle Diseases', 'Cell Line', 'Conserved Sequence', 'DNA, Viral', 'Genome, Viral', 'Herpesviridae Infections', 'Herpesvirus 1, Bovine', 'Polymerase Chain Reaction', 'Sensitivity and Specificity', 'Viral Proteins'] | 8,861,645 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['A11.251.210'], ['G02.111.570.580'], ['D13.444.308.568'], ['G05.360.340.358.840'], ['C01.925.256.466'], ['B04.280.382.100.900.400'], ['E05.393.620.500'], ['E05.318.370.800', 'E05.318.740.872',... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Effects of emulsifying salts on the turbidity and calcium-phosphate-protein interactions in casein micelles. | Influence of emulsifying salts (ES) on some physical properties of casein micelles was investigated. A reconstituted milk protein concentrate (MPC) solution (5% wt/wt) was used as the protein source and the effects of ES [0 to 2.0% (wt/wt)] were estimated by measuring turbidity, acid-base titration curves and amount of... | ['Animals', 'Buffers', 'Calcium', 'Caseins', 'Diphosphates', 'Emulsifying Agents', 'Hydrogen-Ion Concentration', 'Micelles', 'Milk Proteins', 'Nephelometry and Turbidimetry', 'Phosphates', 'Solutions'] | 16,107,395 | [['B01.050'], ['D27.720.470.280'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['D01.029.260.700.675.374.775.150', 'D01.248.497.158.730.650.200', 'D01.695.625.675.650.775.150'], ['D27.720.877.383'], ['G02.300'], ['D05.374', 'D26.255.560'], ['A12.790.520', 'D12.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Screening of fungal beta-xylanases for production of acidic xylooligosaccharides using in situ reduced 4-O-methylglucuronoxylan as substrate. | Fungal beta xylanases were screened for production of acidic xylooligomers from 4-O-methylglucuronoxylan. In situ reduced hardwood xylan was used as substrate because the products of neutral- and acidic-branched xylooligomers help define substrate specificity of the enzymes. Borohydride reduction in situ transformed 30... | ['Basidiomycota', 'Carbohydrate Sequence', 'Chromatography, High Pressure Liquid', 'Chromatography, Ion Exchange', 'Fungi', 'Hydrolysis', 'Hypocreales', 'Molecular Sequence Data', 'Oligosaccharides', 'Spectrophotometry, Ultraviolet', 'Time Factors', 'Trees', 'Trichoderma', 'Xylan Endo-1,3-beta-Xylosidase', 'Xylans', 'X... | 9,291,623 | [['B01.300.179'], ['G02.111.570.160', 'L01.453.245.667.160'], ['E05.196.181.400.300'], ['E05.196.181.400.383'], ['B01.300'], ['G02.380'], ['B01.300.107.501'], ['L01.453.245.667'], ['D09.698.629'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['G01.910.857'], ['B01.650.915'], ['B01.300.381.910'], ['D08.811.277.450.95... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The saddle connective tissue graft: a periodontal plastic surgery technique to obtain soft tissue coronal gain on immediate implants. A case report. | Based on recent studies regarding the advantages of flapless immediate implants on the maintenance of the soft tissue architecture (especially at papillae level) in those situations where it is necessary to extract an anterior tooth, this case report describes a clinical procedure designed to replace a hopeless central... | ['Adult', 'Esthetics, Dental', 'Female', 'Humans', 'Periodontium', 'Surgery, Plastic', 'Young Adult'] | 26,171,446 | [['M01.060.116'], ['E06.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A14.549.167.646'], ['H02.403.810.788'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Aroma Characterization and Safety Assessment of a Beverage Fermented by Trametes versicolor. | A cereal-based beverage was developed by fermentation of wort with the basidiomycete Trametes versicolor. The beverage possessed a fruity, fresh, and slightly floral aroma. The volatiles of the beverage were isolated by liquid-liquid extraction (LLE) and additionally by headspace solid phase microextraction (HS-SPME). ... | ['Animals', 'Beverages', 'Fermentation', 'Flavoring Agents', 'Hazard Analysis and Critical Control Points', 'Hepatocytes', 'Hypericum', 'Odorants', 'Rats', 'Trametes', 'Volatile Organic Compounds'] | 26,189,508 | [['B01.050'], ['G07.203.100', 'J02.200'], ['G02.111.158.249', 'G03.191.249'], ['D26.650.294', 'D27.720.372.300.353', 'D27.720.744.294', 'G07.203.300.514.500.400', 'J02.500.514.500.400'], ['J01.576.423.850.730.500.750', 'N06.850.135.060.075.299', 'N06.850.601.500.750'], ['A11.436.348'], ['B01.650.940.800.575.912.250.859... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Family resources and parental health in families of children with Duchenne muscular dystrophy. | BACKGROUND: This study was based on two models, namely, the resiliency model of family stress, adjustment, and adaptation and the model for family stressors, resources, and function. Family resources, such as family hardiness and support, have previously been shown to improve family adaptation. There is little evidence... | ['Adult', 'Child', 'Family Health', 'Female', 'Humans', 'Linear Models', 'Male', 'Multivariate Analysis', 'Muscular Dystrophy, Duchenne', 'Parents', 'Resilience, Psychological', 'Social Support', 'Taiwan'] | 21,139,443 | [['M01.060.116'], ['M01.060.406'], ['N01.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['E05.318.740.150.500', 'N05.715.360.750.125... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Electrophoresis or iontophoresis in dentistry. 2. Theoretical aspects]. | The Authors, in this second note of study about odontoiatric ionophoresis, define the theoretical side of the ionophoretic separation method. | ['Blood Proteins', 'Densitometry', 'Dentistry', 'Electrophoresis', 'Humans', 'Iontophoresis', 'Spectrophotometry'] | 2,638,551 | [['D12.776.124'], ['E05.196.712.224'], ['E06', 'H02.163'], ['E05.196.401', 'E05.301.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.650', 'E05.301.300.575'], ['E05.196.712.726', 'E05.196.867.826']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Single step selection of cis-diamminedichloroplatinum(II) resistant mutants from a human ovarian carcinoma cell line. | We have shown that cis diamminedichloroplatinum-(II) (DDP) resistant mutants can be isolated from the human ovarian carcinoma cell line A2780 using a single-step selection protocol with DDP. DDP resistant colonies were calculated to be present at a frequency of 1.7 x 10(-6)/viable cell using a fluctuation analysis. The... | ['Aphidicolin', 'Buthionine Sulfoximine', 'Cell Survival', 'Cisplatin', 'Diterpenes', 'Drug Resistance', 'Female', 'Humans', 'Methionine Sulfoximine', 'Mutation', 'Ovarian Neoplasms', 'Phenotype', 'Tumor Cells, Cultured', 'Tumor Stem Cell Assay'] | 1,901,242 | [['D02.455.849.291.075'], ['D02.886.030.676.620.125', 'D12.125.166.676.620.125'], ['G04.346'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D02.455.849.291'], ['G07.690.773.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.030.676.620', 'D12.125.166.676.620'], ['G05.365.590'], ['C04.588.322.455', 'C... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of cycling competition type on effort based on heart rate and session rating of perceived exertion. | AIM: The aim of this study was to compare the exercise intensity and competition load during Time Trial (TT), Flat (FL), Medium Mountain (MM) and High Mountain (HM) stages based heart rate (HR) and session rating of perceived exertion (RPE).METHODS: We monitored both HR and RPE of 12 professional cyclists during two co... | ['Adult', 'Analysis of Variance', 'Athletic Performance', 'Bicycling', 'Competitive Behavior', 'Heart Rate', 'Humans', 'Male', 'Perception', 'Physical Exertion'] | 23,584,322 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['I03.450.642.845.054'], ['I03.450.642.845.140'], ['F01.145.813.105'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593'], ['G11.427.683']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Co-occurrence of celiac disease and other autoimmune diseases in celiacs and their first-degree relatives. | The occurrence of other autoimmune diseases in celiac disease families has not been previously reported in a North American population. We investigated the familial aggregation of rheumatoid arthritis (RA), juvenile rheumatoid arthritis/juvenile idiopathic arthritis (JRA/JIA), hypothyroidism, insulin dependent diabetes... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Autoimmune Diseases', 'Canada', 'Celiac Disease', 'Child', 'Child, Preschool', 'Comorbidity', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Surveys and Questionnaires', 'United States'] | 18,692,362 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C20.111'], ['Z01.107.567.176'], ['C06.405.469.637.250', 'C18.452.603.250'], ['M01.060.406'], ['M01.060.406.448'], ['N05.715.350.225', 'N06.850.490.687'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Sourcing of the WHO human papillomavirus type 18 international standards for HPV antibody levels. | BACKGROUND: HPV serology is important for studies of vaccine immunogenicity, but can not be performed in a comparable manner without international standardisation.OBJECTIVES: To find suitable candidate sera from naturally infected persons for use as International Standards (IS) for antibodies to high-risk HPVs, with pr... | ['Adolescent', 'Adult', 'Aged', 'Antibodies, Viral', 'Cohort Studies', 'Female', 'Human papillomavirus 18', 'Humans', 'Immunoassay', 'Middle Aged', 'Papillomavirus Infections', 'Reference Standards', 'Seroepidemiologic Studies', 'Thailand', 'Young Adult'] | 27,002,710 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B04.280.210.655.050.618', 'B04.613.204.655.050.618'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Color Doppler evaluation of the influence of type of delivery, sex, postnatal age and time post feeding on full term healthy newborns cerebral blood flow. | OBJECTIVE: The purpose of this study was to evaluate with Color Doppler the influence of type of delivery, sex, postnatal age and time post feeding on full term healthy newborns cerebral blood flow.METHOD: 50 newborns were studied. The Doppler parameters, peak-systolic velocity, end-diastolic velocity, mean velocity, p... | ['Age Factors', 'Blood Flow Velocity', 'Cerebrovascular Circulation', 'Delivery, Obstetric', 'Female', 'Humans', 'Infant, Newborn', 'Male', 'Sex Factors', 'Ultrasonography, Doppler, Color', 'Ultrasonography, Doppler, Transcranial'] | 19,623,445 | [['N05.715.350.075', 'N06.850.490.250'], ['E01.370.370.130', 'G09.330.380.630.080'], ['G09.330.100.159'], ['E04.520.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['N05.715.350.675', 'N06.850.490.875'], ['E01.370.350.850.850.850.850'], ['E01.370.350.578.937.260.850', 'E01.370.350.700.560.2... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Anterior approach to the cervicothoracic junction without sternotomy: a report of 37 cases. | STUDY DESIGN: Description of a new anterior approach to the cervicothoracic junction and retrospective study of results.OBJECTIVE: To propose a less invasive anterior approach and report the preliminary results of this technique.SUMMARY OF BACKGROUND DATA: Different partial sternotomies with or without associated clavi... | ['Blood Loss, Surgical', 'Cervical Vertebrae', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Minimally Invasive Surgical Procedures', 'Osteotomy', 'Retrospective Studies', 'Spinal Cord Compression', 'Spinal Injuries', 'Spinal Neoplasms', 'Sternum', 'Thoracic Vertebrae', 'Time Factors', 'Tomo... | 18,246,011 | [['C23.550.414.300', 'C23.550.505.300'], ['A02.835.232.834.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E04.502'], ['E04.555.580'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Radiation induced malignant schwannoma arising in a neurofibroma. | Radiation induced sarcomas offer diagnostic and therapeutic challenges. The authors report an unusual case of radiation induced sarcoma arising 9 years after radiation therapy for chordoma. The location of this mass in the retroperitoneum and its intimate involvement with the spine raised difficult management issues. A... | ['Chordoma', 'Follow-Up Studies', 'Humans', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Neoplasms, Radiation-Induced', 'Neoplasms, Second Primary', 'Neurilemmoma', 'Retroperitoneal Neoplasms', 'Sacrum', 'Spinal Neoplasms'] | 8,998,885 | [['C04.557.465.220'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['C04.682', 'C26.733.476', 'G01.750.748.500.476'], ['C04.692'], ['C04.557.465.625.650.595', 'C04.557.580.600.610... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Liver injury induced in Balb/c mice by PM2.5 | Accumulating evidence has suggested a strong link between exposure to air pollution and public health. In particular, inhaled airborne particulate matter <2.5 ìm in aerodynamic diameter (PM2.5) can rapidly diffuse from the lungs to the systemic blood circulation and accumulate in the liver. In this study, we used a Bal... | ['Air Pollutants', 'Animals', 'Chemical and Drug Induced Liver Injury', 'Inhalation Exposure', 'Liver Function Tests', 'Mice, Inbred BALB C', 'Oils, Volatile', 'Particulate Matter', 'Plants, Medicinal', 'Protective Agents'] | 29,890,467 | [['D27.888.284.101'], ['B01.050'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['N06.850.460.350.112'], ['E01.370.372.460'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['D10.627.675'], ['D20.633'], ['B01.650.560'], ['D27.505.696.706', 'D27.720.799']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Intensive chemotherapy and low-dose radiotherapy for the treatment of advanced-stage Hodgkin's disease in pediatric patients: a Pediatric Oncology Group study. | Sixty-two patients with advanced-stage Hodgkin's disease and a median age of 12 years (range, 3 to 22 years) were treated with four cycles of mechlorethamine, vincristine, procarbazine, and prednisone (MOPP) alternating with four cycles of doxorubicin, vinblastine, bleomycin, and dacarbazine (ABVD) followed by low-dose... | ['Adolescent', 'Adult', 'Antineoplastic Combined Chemotherapy Protocols', 'Bleomycin', 'Child', 'Child, Preschool', 'Combined Modality Therapy', 'Dacarbazine', 'Doxorubicin', 'Female', 'Hodgkin Disease', 'Humans', 'Male', 'Mechlorethamine', 'Neoplasm Staging', 'Prednisone', 'Procarbazine', 'Prognosis', 'Remission Induc... | 1,714,950 | [['M01.060.057'], ['M01.060.116'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D09.400.420.110', 'D12.644.233.110'], ['M01.060.406'], ['M01.060.406.448'], ['E02.186'], ['D02.925.200', 'D03.383.129.308.240'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
R102Q mutation shifts the salt-bridge network and reduces the structural flexibility of human neuronal calcium sensor-1 protein. | Neuronal calcium sensor-1 (NCS-1) protein has a variety of different neuronal functions and interacts with multiple binding partners mostly through a large solvent-exposed hydrophobic crevice (HC). A single R102Q mutation in human NCS-1 protein was demonstrated to be associated with autism disease. Solution NMR study r... | ['Amino Acid Sequence', 'Amino Acid Substitution', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Molecular Dynamics Simulation', 'Molecular Sequence Data', 'Neuronal Calcium-Sensor Proteins', 'Neuropeptides', 'Nuclear Magnetic Resonance, Biomolecular', 'Protein Structure, Tertiary', 'Salts', 'Thermodynamics'] | 25,343,687 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.409'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['L01.453.245.667'], ['D12.644.360.372.500', 'D12.776.157.125.412.500', 'D12.776.476.387.500', 'D12.776.631.645'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The Src family of tyrosine kinases is important for embryonic stem cell self-renewal. | cYes, a member of the Src family of non-receptor tyrosine kinases, is highly expressed in mouse and human embryonic stem (ES) cells. We demonstrate that cYes kinase activity is regulated by leukemia inhibitory factor (LIF) and serum and is down-regulated when cells differentiate. Moreover, selective chemical inhibition... | ['Animals', 'Base Sequence', 'Cell Differentiation', 'Cell Division', 'Cell Line', 'DNA Primers', 'Gene Expression', 'Humans', 'Interleukin-6', 'Leukemia Inhibitory Factor', 'MAP Kinase Signaling System', 'Mice', 'Pluripotent Stem Cells', 'Proteins', 'RNA, Small Interfering', 'src-Family Kinases'] | 15,148,312 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Antipyrine clearance in liver resections]. | We studied antipyrine clearance (APC1) in 19 healthy controls, 10 cirrhotic patients, 20 patients undergoing partial hepatectomy for liver tumors (14 with cirrhosis and 6 without cirrhosis). The aim of the study was to evaluate if the test represents a measure of the residual hepatic function and a useful index of surg... | ['Adult', 'Aged', 'Antipyrine', 'Female', 'Hepatectomy', 'Humans', 'Liver', 'Liver Cirrhosis', 'Liver Function Tests', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Spectrophotometry'] | 2,089,284 | [['M01.060.116'], ['M01.060.116.100'], ['D03.383.129.539.850.088'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['C06.552.630', 'C23.550.355.412'], ['E01.370.372.460'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.060.116.630'], ['E05.196.712.726', 'E05.196.867.826']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Complexation between á-cyclodextrin and PEGylated-PAMAM dendrimers at low and high pH values. | Poly(ethylene glycol)-grafted-poly(amido amine) (PEGylated-PAMAM) dendrimers have attracted increasing amounts of attention because of their improved stability, toxicity, and better particle drug leakage property. The complexation of á-cyclodextrin (á-CD) with grafted PEG segments on the surface of PAMAM dendrimers was... | ['Amines', 'Calorimetry', 'Chemistry', 'Dendrimers', 'Drug Delivery Systems', 'Hydrogen Bonding', 'Hydrogen-Ion Concentration', 'Light', 'Polyethylene Glycols', 'Scattering, Radiation', 'Static Electricity', 'alpha-Cyclodextrins'] | 21,038,877 | [['D02.092'], ['E05.196.131'], ['H01.181'], ['D05.750.327', 'E02.319.300.380.200', 'J01.637.512.600.200'], ['E02.319.300'], ['G02.282'], ['G02.300'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['E05.196.822'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Novel monomeric luciferase enzymes as tools to study plant gene regulation in vivo. | Taking advantage of a specially constructed vector, luciferase LuxA and LuxB subunits were connected in frame to different amino acid linkers to reproduce a series of monomeric luciferase enzymes. A comparison of their activities in E. coli cells demonstrated that the length of the linkers positively affected activity.... | ['Amino Acid Sequence', 'Base Sequence', 'Escherichia coli', 'Gene Expression Regulation', 'Genes, Bacterial', 'Genetic Vectors', 'Luciferases', 'Macromolecular Substances', 'Molecular Sequence Data', 'Plants', 'Plants, Toxic', 'Plasmids', 'Restriction Mapping', 'Tobacco', 'Vibrio'] | 2,186,598 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.360.337'], ['D08.811.682.517', 'D12.776.532.510'], ['D... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Organizational technologies of chronic disease management programs in large rural multispecialty group practice systems. | Four large rural multispecialty group practice systems employ a mix of organizational technologies to provide chronic disease management with measurable impacts on their patient populations and costs. Four technologies-administrative, clinical, information, and social-are proposed as key dimensions for examining diseas... | ['Chronic Disease', 'Disease Management', 'Group Practice', 'Humans', 'Medicine', 'Rural Health Services', 'Specialization', 'Technology', 'United States'] | 15,968,213 | [['C23.550.291.500'], ['N04.590.607'], ['N04.452.758.244'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403'], ['N02.421.816'], ['H02.811'], ['J01.897'], ['Z01.107.567.875']] | ['Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
The effects of calcitonin on acute bone loss after pertrochanteric fractures. A prospective, randomised trial. | We investigated the effect of calcitonin in the prevention of acute bone loss after a pertrochanteric fracture and its ability to reduce the incidence of further fractures in the same patient. Fifty women aged between 70 and 80 years who had a pertrochanteric fracture of the hip were randomly allocated to group A (200 ... | ['Acute Disease', 'Administration, Intranasal', 'Aged', 'Aged, 80 and over', 'Alkaline Phosphatase', 'Biomarkers', 'Bone Density', 'Calcitonin', 'Collagen', 'Collagen Type I', 'Female', 'Hip Fractures', 'Humans', 'Hydroxyproline', 'Osteocalcin', 'Osteolysis', 'Peptides', 'Prospective Studies', 'Recurrence'] | 15,125,121 | [['C23.550.291.125'], ['E02.319.267.120.655.500'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.277.352.650.035'], ['D23.101'], ['G11.427.100'], ['D06.472.699.150', 'D06.472.931.052', 'D12.644.400.095', 'D12.644.548.150', 'D12.776.631.650.095'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D05.750.078.280.3... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The prevalence of distraction among passenger vehicle drivers: a roadside observational approach. | OBJECTIVE: Distracted driving contributes to a large proportion of motor vehicle crashes, yet little is known about the prevalence of distracted driving and the specific types of distracting behaviors. The objective of this study was to estimate the prevalence of driver distraction using a roadside observational study ... | ['Adult', 'Attention', 'Automobile Driving', 'Cell Phone', 'Cross-Sectional Studies', 'Female', 'Humans', 'Interpersonal Relations', 'Male', 'Middle Aged', 'Prevalence', 'Text Messaging'] | 24,761,827 | [['M01.060.116'], ['F02.830.104.214'], ['I03.125'], ['L01.178.847.698.300'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.7... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Accounting for station connections, optional payment in revenues and related capital costs, customer provided equipment and sale of terminal equipment--Federal Communications Commission. Order on reconsideration and clarification of first report and order. | This document sets for the Commissions response to a petition for clarification and a petition for reconsideration of its First Report and Order, Commonly known as "Expensing of Station Connections". The First Report and Order, published in the Federal Register at 456 FR 18481, March 31, 1981, adopted changes to the Co... | ['Accounting', 'Telephone', 'United States'] | 10,255,076 | [['N03.219.463.030'], ['L01.178.847.698'], ['Z01.107.567.875']] | ['Health Care [N]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Dual-tree complex wavelet transform and image block residual-based multi-focus image fusion in visual sensor networks. | This paper presents a novel framework for the fusion of multi-focus images explicitly designed for visual sensor network (VSN) environments. Multi-scale based fusion methods can often obtain fused images with good visual effect. However, because of the defects of the fusion rules, it is almost impossible to completely ... | ['Algorithms', 'Humans', 'Image Interpretation, Computer-Assisted', 'Image Processing, Computer-Assisted', 'Visual Perception', 'Wavelet Analysis'] | 25,587,878 | [['G17.035', 'L01.224.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['L01.224.308'], ['F02.463.593.932'], ['E05.959', 'G17.915', 'L01.224.800.750']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The difficult gall bladder: Outcomes following laparoscopic cholecystectomy and the need for open conversion. | INTRODUCTION: Surgery for the difficult gallbladder (DGB) is associated with increased risk compared to more routine laparoscopic cholecystectomies (LC). Laparoscopic "damage control" methods including cholecystostomy, fundus-down approach and subtotal cholecystectomy (SC) have been proposed to avoid conversion to open... | ['Aged', 'Cholecystectomy, Laparoscopic', 'Conversion to Open Surgery', 'Female', 'Gallbladder Diseases', 'Humans', 'Male', 'Retrospective Studies'] | 28,340,928 | [['M01.060.116.100'], ['E04.210.120.172.140', 'E04.502.250.520.160'], ['E04.502.250.155'], ['C06.130.564'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.45... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Smart poly(N-isopropylacrylamide) containing iridium(III) complexes as water-soluble phosphorescent probe for sensing and bioimaging of homocysteine and cysteine. | Homocysteine (Hcy) and cysteine (Cys) are two important kinds of amino acids in human bodies. Herein, we synthesized an iridium(III) complex-functionalized poly(N-isopropylacrylamide) and its hydrogel, which could be used as the excellent phosphorescent bioprobe for sensing Hcy and Cys. Their detection can be realized ... | ['Acrylamides', 'Acrylic Resins', 'Cell Line, Tumor', 'Cell Survival', 'Coordination Complexes', 'Cysteine', 'Fluorescent Dyes', 'Homocysteine', 'Humans', 'Hydrogel, Polyethylene Glycol Dimethacrylate', 'Iridium', 'Microscopy, Confocal', 'Polymers', 'Temperature', 'Water'] | 23,060,120 | [['D02.065.122', 'D02.241.081.069.094'], ['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['D01.234', 'D02.257'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D27.720.233.348', 'D27.720.470.410.505.500'... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Skin changes following defibrillation. The effect of high voltage direct current. | Previously, electrical injuries have been suggested caused only by the concomitant heat developed during the passage of an electrical current. Recent experimental studies on fully anesthetized pigs and the study of one human case have, however, shown typical electrical alterations. The purpose of the present study was ... | ['Biopsy', 'Burns, Electric', 'Cytoplasm', 'Electric Countershock', 'Electrodes', 'Humans', 'Keratinocytes', 'Necrosis', 'Skin', 'Ultrasonography'] | 12,850,408 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C26.200.239', 'C26.324.323'], ['A11.284.430.214'], ['E02.331.350'], ['E07.305.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.409.500', 'A11.436.397'], ['C23.55... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of the lipid profile in type 2 diabetes mellitus patients in Greece. | BACKGROUND: Diabetes mellitus (DM) is one of the most serious global health problems. In Greece, DM constitutes a public health problem and is highly associated with decreasing levels of physical activity, increasing obesity rates, population ageing, and unhealthy lifestyle and dietary behaviors.MATERIALS: In this stud... | ['Area Under Curve', 'Biomarkers', 'Blood Glucose', 'Case-Control Studies', 'Chi-Square Distribution', 'Diabetes Mellitus, Type 2', 'Dyslipidemias', 'Female', 'Glycated Hemoglobin A', 'Greece', 'Humans', 'Linear Models', 'Lipids', 'Logistic Models', 'Male', 'Prevalence', 'ROC Curve', 'Sex Factors'] | 25,651,703 | [['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D23.101'], ['D09.947.875.359.448.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C18.452.394.750.149', 'C... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Branch retinal vein occlusion: the pathogenetic role of blood viscosity. | The pathogenesis of branch retinal vein occlusion has not been completely clarified. The role of abnormal blood viscosity in the appearance and evolution of the disease has recently been advocated. We studied 54 patients with long-standing branch retinal vein occlusion from a hemorrheologic point of view. Depending on ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Blood Viscosity', 'Diabetes Mellitus, Type 2', 'Erythrocyte Deformability', 'Female', 'Fibrinogen', 'Fluorescein Angiography', 'Fundus Oculi', 'Hematocrit', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Retinal Vein Occlusion'] | 2,221,710 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G09.188.370.124', 'G09.330.380.630.110'], ['C18.452.394.750.149', 'C19.246.300'], ['G09.188.370.249'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['E01.370.370.050.350', 'E01.370.380.250'], ['A09.371.729.313'], ['E0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neuro-fuzzy technology as a predictor of parathyroid hormone level in hemodialysis patients. | Measuring the plasma parathyroid hormone (PTH) concentration is crucial to evaluate renal bone disease in patients with renal failure. Although frequent measurement is needed to avoid inadequate prescription of phosphate binders and vitamin D preparations, artificial intelligence can repeatedly perform the forecasting ... | ['Aged', 'Algorithms', 'Alkaline Phosphatase', 'Blood Chemical Analysis', 'Calcium', 'Female', 'Fuzzy Logic', 'Humans', 'Hyperparathyroidism, Secondary', 'Male', 'Middle Aged', 'Neural Networks, Computer', 'Parathyroid Hormone', 'Phosphorus', 'Radioimmunoassay', 'Regression Analysis', 'Renal Dialysis', 'Renal Insuffici... | 17,202,775 | [['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['D08.811.277.352.650.035'], ['E01.370.225.124.100', 'E05.200.124.100'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.642.355.480'], ['M01.060.116... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Colonic metastases from lobular carcinoma of the breast. Report of a case. | Metastatic involvement of the gastrointestinal tract secondary to breast cancer is rare. A case of diffuse infiltration of the colon by metastatic infiltrating lobular breast cancer is reported. Awareness of this condition may lead to proper investigations including intestinal biopsy, thus avoiding unnecessary surgery. | ['Breast Neoplasms', 'Carcinoma', 'Colonic Neoplasms', 'Female', 'Humans', 'Middle Aged'] | 3,366,041 | [['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Metabolic profiles of the Flos Abelmoschus manihot extract by intestinal bacteria from the normal and CKD model rats based on UPLC-Q-TOF/MS. | Flos Abelmoschus manihot is a traditional herbal medicine widely used in clinical practice to tackle chronic kidney disease (CKD) for thousands of years. Nowadays, many studies indicate that gut bacteria are closely related to the progression of CKD and CKD-related complications. In this study, a UPLC-Q-TOF/MS method c... | ['Abelmoschus', 'Animals', 'Chromatography, High Pressure Liquid', 'Drugs, Chinese Herbal', 'Flavonoids', 'Intestinal Mucosa', 'Intestines', 'Male', 'Malvaceae', 'Mass Spectrometry', 'Metabolome', 'Quercetin', 'Rats', 'Rats, Sprague-Dawley', 'Renal Insufficiency, Chronic'] | 27,451,133 | [['B01.650.940.800.575.912.250.859.821.500.100'], ['B01.050'], ['E05.196.181.400.300'], ['D20.215.784.500.350', 'D26.335'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124'], ['B01.650.940.800.575.912.250.859.821.500'], ['E05.196.566'], ['G03.500'], ['D03.38... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Two Gamispatulus Thatcher amp; Boger, 1984 (Cyclopoida: Ergasilidae) from Schizodon intermedius Garavello amp; Britski (Actinopterygii: Anostomidae), with description of a new species. | A parasitological survey of fishes from two tributaries (Veados and Paranapananema Rivers) of the Jurumirim Reservoir, Upper Paranapanema River, S?o Paulo State, Brazil, was carried out a during a sampling survey in 2011 and 2012. Several ectoparasitic copepods were found inside the nostrils of the freshwater anostomid... | ['Animals', 'Characiformes', 'Copepoda', 'Fish Diseases', 'Rivers'] | 33,056,005 | [['B01.050'], ['B01.050.150.900.493.130'], ['B01.050.500.131.365.160'], ['C22.362'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The protonmotive force in bovine heart submitochondrial particles. Magnitude, sites of generation and comparison with the phosphorylation potential. | 1. The magnitude of the protonmotive force in respiring bovine heart submitochondrial particles was estimated. The membrane-potential component was determined from the uptake of S14CN-ions, and the pH-gradient component from the uptake of [14C]methylamine. In each case a flow-dialysis technique was used to monitor upta... | ['Adenosine Triphosphate', 'Animals', 'Ascorbic Acid', 'Cattle', 'Electrochemistry', 'In Vitro Techniques', 'Membrane Potentials', 'Mitochondria', 'Mitochondria, Heart', 'NAD', 'Osmolar Concentration', 'Phosphorylation', 'Protons', 'Submitochondrial Particles', 'Succinates'] | 212,021 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['B01.050.150.900.649.313.500.380.271'], ['H01.181.529.307'], ['E05.481'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['A11.284.430.214.190.875.564',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Evidence for the involvement of several intracellular domains in the coupling of oxytocin receptor to G alpha(q/11). | In order to probe the nature of oxytocin receptor (OTR)/G alpha(q/11) protein coupling, we examined the effect of co-expression of OTR intracellular domains on oxytocin-stimulated phosphoinositide turnover in COSM6 cells overexpressing OTR and G alpha(q). Co-expression of G alpha(q) enhanced the oxytocin response maxim... | ['Amino Acid Sequence', 'Animals', 'Binding Sites', 'COS Cells', 'GTP-Binding Proteins', 'Humans', 'Molecular Sequence Data', 'Phosphatidylinositols', 'Receptors, Oxytocin', 'Recombinant Proteins', 'Transfection'] | 9,481,484 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['A11.251.210.172.500', 'A11.329.228.220'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['D10.570.755.375.760.400.942'], ['D12.776.543.750.695.630', 'D12.776.543.750.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effective knock down of very high ABCG2 expression by a hammerhead ribozyme. | BACKGROUND: Ribozymes are an effective tool to reduce the mRNA levels of specific target genes. Overexpression of the drug transport protein, ABCG2, has been associated with multidrug resistance in cancer cells.MATERIALS AND METHODS: An expression plasmid encoding a hammerhead ribozyme against the ABCG2 gene was stably... | ['ATP Binding Cassette Transporter, Subfamily G, Member 2', 'ATP-Binding Cassette Transporters', 'Antineoplastic Agents', 'Breast Neoplasms', 'Cell Line, Tumor', 'Drug Resistance, Neoplasm', 'Humans', 'Methotrexate', 'Mitoxantrone', 'Neoplasm Proteins', 'RNA, Catalytic', 'Reverse Transcriptase Polymerase Chain Reaction... | 15,330,166 | [['D12.776.157.530.100.228.500', 'D12.776.395.550.020.457.500', 'D12.776.543.550.192.457.500', 'D12.776.543.585.100.228.500'], ['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Utilization of Fourier transform-Raman spectroscopy for the study of pharmaceutical crystal forms. | It is well understood that the solid state physical characterization of a drug substance is necessary for successful development and approval of a pharmaceutical product AAPS [1]. Physical analytical techniques used include: XRD, IR, DSC, TG, and NMR. Recently, Fourier transform (FT) Raman spectroscopy has become a mor... | ['Crystallography', 'Fourier Analysis', 'Spectrophotometry, Infrared', 'Spectrum Analysis, Raman'] | 9,547,695 | [['E05.196.309', 'H01.181.529.240'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['E05.196.712.726.676', 'E05.196.867.826.676'], ['E05.196.822.860', 'E05.196.867.890']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Central pontine myelinolysis manifested by temporary blindness: a possible complication of lithium toxicity. | Central pontine myelinolysis (CPM) is removal of myelin material from neural elements in a way that is not clearly known as yet. In this case of CPM, blindness was encountered and was thought to be "hysterical." The blindness went away after four months. After reviewing the literature we suggest the CPM was a complicat... | ['Adult', 'Antimanic Agents', 'Bipolar Disorder', 'Blindness', 'Delirium', 'Female', 'Follow-Up Studies', 'Geniculate Bodies', 'Humans', 'Intracranial Pressure', 'Lithium Compounds', 'Low Back Pain', 'Magnetic Resonance Imaging', 'Myelinolysis, Central Pontine', 'Neurologic Examination', 'Tegmentum Mesencephali'] | 12,630,660 | [['M01.060.116'], ['D27.505.696.277.950.025', 'D27.505.954.427.210.950.025', 'D27.505.954.427.700.872.025'], ['F03.084.500'], ['C10.597.751.941.162', 'C11.966.075', 'C23.888.592.763.941.162'], ['C10.597.606.337.500', 'C23.888.592.604.339.500', 'F01.700.250.500', 'F03.615.350'], ['E05.318.372.500.750.249', 'N05.715.360.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Medical themes in a literature classroom: An alternate perspective on Medical Humanities pedagogy in India. | This article examines the transferability of conversations in literary studies to a more sensitive, holistic, ethically informed, medical education. The article begins with a discussion of a class assignment on medical humanities in a literature course. The assignment enabled an immersive engagement with medical discou... | ['Curriculum', 'Education, Medical, Undergraduate', 'Humanities', 'Humans', 'India', 'Learning', 'Narration', 'Professional Competence', 'Reading', 'Students, Medical', 'Teaching'] | 30,156,557 | [['I02.158'], ['I02.358.399.450'], ['K01'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['F02.463.425', 'F02.784.629.529'], ['E05.318.308.502', 'F01.145.209.459', 'L01.399.250.660', 'N05.715.360.300.480', 'N06.850.520.308.502'], ['I02.399.630'], ['L01.559.423.557'], ['M01.848.769.602'], ['I02.... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Expression and functional activity of isotype and subclass switched human monoclonal antibody reactive with the base of the V3 loop of HIV-1 gp120. | Immunoglobulins undergo isotype switching in response to antigenic stimulation. The C(H) domains, in particular the hinge region, impose structural constraints on the interaction of antibody with antigen, especially multivalent antigens such as HIV. We previously showed that switching the IgG1 anti-HIV human monoclonal... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Antibody Specificity', 'Antigen-Antibody Reactions', 'Base Sequence', 'Cloning, Molecular', 'Epitopes', 'Genes, Immunoglobulin', 'HIV Antibodies', 'HIV Antigens', 'HIV Envelope Protein gp120', 'HIV-1', 'Humans', 'Hybridomas', 'Immunoglobulin A', 'Immunoglobu... | 12,908,937 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.100'], ['G12.122'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D23.050.550'], ['G05.360.340.024.340.335', 'G12.500.299'], ['D1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Psychotherapy and the aged. | Psychotherapy for ageing or old people is defined and described, and certain theoretical and practical aspects are dealt with. Special emphasis is laid on the direction and movement of a series of therapeutic encounters, so as to make clear, even to the non-specialist reader, what the patient might expect to gain from ... | ['Aged', 'Attitude to Death', 'Conflict, Psychological', 'Geriatric Psychiatry', 'Hate', 'Humans', 'Physician-Patient Relations', 'Psychotherapy'] | 1,224,279 | [['M01.060.116.100'], ['F01.100.125', 'N05.300.125'], ['F01.658.209'], ['F04.096.544.380', 'H02.403.690.260'], ['F01.470.548'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.650.675', 'N05.300.660.625'], ['F04.754']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
The variable transformation in metastases from testicular germ cell tumors: the need for selective biopsy. | The propensity for metastatic testicular teratocarcinoma to undergo differentiation, particularly when associated with successful cancer chemotherapy, means that the histology of residual disease following chemotherapy cannot be assumed without biopsy. We present 4 cases in which biopsy of a metastasis was important in... | ['Adolescent', 'Adult', 'Biopsy', 'Humans', 'Male', 'Teratoma', 'Testicular Neoplasms'] | 7,253,077 | [['M01.060.057'], ['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.910'], ['C04.588.322.762', 'C04.588.945.440.915', 'C12.294.260.937', 'C12.758.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The correlation between milk flow, vacuum fluctuations and decrease in vacuum in the long milk tube at the claw in different milking machines. An introductory examination (author's transl)]. | Four different milking machines have been examined for vacuum fluctuations and vacuum decrease in the long milk tube at the claw. Measurements were performed in 3 cows milked with Alfa-Laval high line HP 100, 11 cows in 3 herds milked with Alfa-Laval high line Duovac 300, 5 cows milked with Erland low line milking equi... | ['Animals', 'Cattle', 'Dairying', 'Milk'] | 7,232,139 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['J01.040.246'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525']] | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Acceptability of the consumer-centric u-health services for patients with chronic obstructive pulmonary disease. | OBJECTIVES: We developed and implemented a system for u-health (ubiquitous healthcare) services for patients with chronic obstructive pulmonary disease (COPD) and studied the level of acceptability by the patients in the context of home visits and telephone education.SUBJECTS AND METHODS: To determine its effectiveness... | ['Cell Phone', 'Home Care Services', 'Humans', 'Monitoring, Ambulatory', 'Patient Education as Topic', 'Patient Satisfaction', 'Pulmonary Disease, Chronic Obstructive', 'Telemedicine'] | 22,510,084 | [['L01.178.847.698.300'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.520.500'], ['I02.233.332.500', 'N02.421.726.407.680'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600'], ['C08.381.495.389'], ['H02.403.... | ['Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Endoscopic ablation of esophageal malignancies with the neodymium-YAG laser and electrofulguration. | The case reports of 40 patients with obstructive esophageal cancer treated with electrofulguration (EF) or neodymium (Nd)-YAG laser were reviewed. Surgery was contraindicated because of advanced carcinoma (17 patients), recurrence after resection (13 patients), recurrence after irradiation (four patients), and poor med... | ['Adult', 'Aged', 'Aged, 80 and over', 'Electrosurgery', 'Endoscopy', 'Esophageal Neoplasms', 'Female', 'Humans', 'Laser Therapy', 'Male', 'Middle Aged', 'Palliative Care', 'Retrospective Studies'] | 2,464,983 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.262'], ['E01.370.388.250', 'E04.502.250'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['M01.060.116.630'], ['E02.76... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Treatment-resistant schizophrenia]. | Schizophrenia is a psychiatric disorder that causes severe cognitive, behavioral and social dysfunction, responsible for a shortening of the life expectancy of patients, with an increased risk of suicide, cardiovascular disease and cancer. The management of patient with schizophrenia is global and atypical antipsychoti... | ['Antipsychotic Agents', 'Brief Psychiatric Rating Scale', 'Clozapine', 'Drug Resistance', 'Humans', 'Receptors, Muscarinic', 'Receptors, N-Methyl-D-Aspartate', 'Receptors, Serotonin', 'Schizophrenia', 'Treatment Outcome'] | 25,102,584 | [['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F04.711.513.653.083'], ['D03.633.300.240.220'], ['G07.690.773.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.750.695.475', 'D12.776.543.750.720.360.500'], ['D12.776.157.530.400.400.500.500', 'D12.776.543... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Insulin clamp-derived measurements of insulin sensitivity and insulin secretion in lean and obese asian type 2 diabetic patients. | BACKGROUND: The aim of this study was to investigate insulin sensitivity and secretion in lean and obese Asian (Thai) type 2 diabetic patients.METHODS: Insulin sensitivity and insulin secretion was assessed with the hyperinsulinemic euglycemic (80 mU/m(2) per min) and hyperglycemic clamp technique in 9 lean and 10 obes... | ['Adult', 'Asian Continental Ancestry Group', 'Diabetes Mellitus, Type 2', 'Female', 'Glucose Clamp Technique', 'Humans', 'Insulin', 'Insulin Resistance', 'Insulin Secretion', 'Male', 'Middle Aged', 'Obesity', 'Thinness'] | 20,059,360 | [['M01.060.116'], ['M01.686.508.200'], ['C18.452.394.750.149', 'C19.246.300'], ['E01.370.225.124.100.350', 'E05.196.500', 'E05.200.124.100.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['G03.442', '... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Assessing guideline adherence and patient outcomes in cervical cancer. | AIM: To investigate adherence to clinical practice guidelines (CPGs) in cervical cancer and the correlation with clinical outcomes.METHODS: A retrospective analysis was conducted using patient information from a population-based cancer registry (2005-2011, n = 208). Compliance to 10 widely accepted CPGs was assessed. U... | ['Cohort Studies', 'Female', 'Guideline Adherence', 'Gynecology', 'Humans', 'Medical Oncology', 'Retrospective Studies', 'Treatment Outcome', 'Uterine Cervical Neoplasms'] | 27,726,297 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N04.761.337', 'N05.715.360.395'], ['H02.403.763.750', 'H02.403.810.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.429.515'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Use of the diaphragm to reinforce anastomosis of the intestines. | Use of a diaphragmatic flap to buttress and help secure persistent intestinal fistula is described. The potential for the use of muscle flaps in the management of recurrent intestinal fistula is presented. | ['Anastomosis, Surgical', 'Diaphragm', 'Humans', 'Intestinal Fistula', 'Intestines', 'Surgical Flaps'] | 2,006,461 | [['E04.035'], ['A02.633.567.900.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.267.550', 'C06.405.469.471', 'C23.300.575.185.550'], ['A03.556.124'], ['A10.850.710', 'E07.862.710']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association between institutional procedural preference and in-hospital outcomes in laparoscopic surgeries; Insights from a retrospective cohort analysis of a nationwide surgical database in Japan. | OBJECTIVE: To assess the use of laparoscopic surgeries (LS) and the association between its performance and hospitals' preference for LS over open surgeries.SUMMARY BACKGROUND DATA: LS is increasingly used in many abdominal surgeries, albeit both with and without solid guideline recommendations. To date, the hospitals'... | ['Colectomy', 'Databases, Factual', 'Female', 'Gastrectomy', 'Humans', 'Japan', 'Laparoscopy', 'Male', 'Models, Biological', 'Practice Guidelines as Topic', 'Registries', 'Retrospective Studies'] | 29,505,561 | [['E04.210.219'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E05.599.395'], ['N04.761.700.350.650', 'N05.700.350.650'], ['E05.318.308.970', 'N04.452.859.819', 'N05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Effect of hydration in metHb: reversible changes monitored by ESR of iron. | The dehydration of human and bovine methemoglobins was monitored using ESR spectroscopy of the iron signal. The interconversion of the Fe(III) signal between the high spin form (at g approximately 6) in solution and low spin form (at g approximately 2) was quantitatively studied as a function of hydration. The dehydrat... | ['Animals', 'Cattle', 'Cysteine', 'Electron Spin Resonance Spectroscopy', 'Ethylmaleimide', 'Ferric Compounds', 'Ferrous Compounds', 'Freeze Drying', 'Hemeproteins', 'Hemoglobins', 'Humans', 'Iron', 'Methemoglobin', 'Protein Conformation', 'Water'] | 1,964,956 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['E05.196.867.519.274'], ['D02.241.081.337.502.524.418', 'D02.478.440.418', 'D03.383.129.578.399.418'], ['D01.490.100'], ['D01.490.200'], ['E01.370.225.500.620.760.160.260', 'E01.370.225.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cloning and expression of the metE gene in Escherichia coli. | A lambda-transducing phage was isolated that contains the metE gene. This gene codes for N5-methyl-H4-folate:homocysteine methyltransferase (EC 2.1.1.14), an enzyme that catalyzes the terminal reaction in methionine biosynthesis. A 9.1-kb EcoR1 fragment of this phage, containing the metE gene, was then cloned into pBR3... | ['Bacteriophage lambda', 'Centrifugation, Density Gradient', 'Cloning, Molecular', 'DNA Restriction Enzymes', 'Escherichia coli', 'Gene Expression Regulation', 'Genes, Bacterial', 'Methyltransferases', 'Microscopy, Electron', 'Phenotype', 'Plasmids', 'Transduction, Genetic'] | 2,988,449 | [['B04.123.150.800.230', 'B04.123.205.230', 'B04.280.090.800.230'], ['E05.181.724.336', 'E05.196.941.336'], ['E05.393.220'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308'], ['G05.360.340.024.340.364.249', 'G05.360.34... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Therapeutic Hypothermia and Stent Thrombosis: A Nationwide Analysis. | OBJECTIVES: This study sought to determine whether "real-world" data supported the hypothesis that therapeutic hypothermia (TH) led to increased rates of stent thrombosis.BACKGROUND: TH, which is often instituted after cardiac arrest (CA) to improve neurologic outcomes, alters pharmacokinetics of antiplatelet medicatio... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Chi-Square Distribution', 'Coronary Thrombosis', 'Databases, Factual', 'Female', 'Heart Arrest', 'Hospital Mortality', 'Humans', 'Hypothermia, Induced', 'Incidence', 'Length of Stay', 'Linear Models', 'Logistic Models', 'Male', 'Middle Aged', 'Myocardial Infarction'... | 27,609,254 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C14.280.647.250.290', 'C14.907.355.830.220', 'C14.907.585.250.290'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['C14.280.383'], ['E05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Resection of endobronchial tumors using a tracheoscope and neodymium:YAG laser. | A modified technique for palliative resections of malignant endobronchial tumors with the Nd:YAG laser is described. A special tracheoscope was used in conjunction with the instrument guide of a laser bronchoscope. The main advantage of this technique is easy and simultaneous access to both lungs for ventilation and su... | ['Bronchial Neoplasms', 'Bronchoscopy', 'Endoscopes', 'Humans', 'Laser Therapy', 'Palliative Care', 'Trachea'] | 1,706,825 | [['C04.588.894.797.520.109', 'C08.127.265', 'C08.785.520.100'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['E07.230.220', 'E07.858.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['E02.760.666', 'N02.421.585.666'], ['A04.889']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Predation by beetles (Carabidae, Staphylinidae) on eggs and juveniles of the Iberian slug Arion lusitanicus in the laboratory. | Arion lusitanicus has become a major pest species in western Norway in the last few years. This species originates from southern Europe but has been spread by humans over large parts of central and northern Europe during recent decades. Slugs have traditionally been controlled by the use of molluscicides; but, as these... | ['Animals', 'Body Size', 'Coleoptera', 'Food Preferences', 'Gastropoda', 'Ovum', 'Pest Control, Biological', 'Predatory Behavior', 'Species Specificity'] | 20,158,927 | [['B01.050'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['B01.050.500.131.617.720.500.500.375'], ['F01.145.407.516', 'G07.203.650.353.516'], ['B01.050.500.644.400'], ['A05.360.490.690', 'A11.497.497', 'A16.690'], ['N06.850.780.200.650.650'], ['F01.145.113.111.600', 'F01.145.1... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The prevalence of erectile dysfunction among Brazilian men screened for prostate cancer. | OBJECTIVE: To determine the prevalence of erectile dysfunction (ED) in a large cohort of Brazilian men who were screened for prostate cancer, and to determine risk factors in this population, as there are large cultural differences among countries in reporting the frequency of ED, and it is likely that the prevalence o... | ['Aged', 'Aged, 80 and over', 'Body Mass Index', 'Brazil', 'Epidemiologic Methods', 'Humans', 'Impotence, Vasculogenic', 'Male', 'Mass Screening', 'Middle Aged', 'Obesity', 'Prostatic Neoplasms', 'Prostatism', 'Quality of Life'] | 19,426,190 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['Z01.107.757.176'], ['E05.318', 'N06.850.520'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.644.486.500'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Community perception and risk reduction practices toward malaria and dengue: A mixed-method study in slums of Chetla, Kolkata. | Background: Globally, vector-borne diseases account for 17% of infectious disease burden. In India, despite accelerated efforts, both malaria and dengue are major public health concern. Understanding local community perspectives is essential to strengthen ongoing program activities.Objectives: The study aimed to assess... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Communicable Disease Control', 'Community Participation', 'Cross-Sectional Studies', 'Dengue', 'Environment', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'India', 'Insect Repellents', 'Insecticide-Treated Bednets', 'Malaria', 'Male', 'Middle Aged', 'Mosqu... | 31,552,845 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['N06.850.780.200'], ['N02.421.143.212', 'N03.540.245.360'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C01.920.500.270', 'C01.925.081.270', 'C01.925.782.350.250.214', 'C01.925.782.417.2... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]',... | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
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