Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Analytical functions to predict cosmic-ray neutron spectra in the atmosphere. | Estimation of cosmic-ray neutron spectra in the atmosphere has been an essential issue in the evaluation of the aircrew doses and the soft-error rates of semiconductor devices. We therefore performed Monte Carlo simulations for estimating neutron spectra using the PHITS code in adopting the nuclear data library JENDL-H... | ['Algorithms', 'Atmosphere', 'Computer Simulation', 'Cosmic Radiation', 'Models, Theoretical', 'Neutrons', 'Radiation Dosage', 'Radiation Monitoring', 'Spectrum Analysis'] | 16,953,673 | [['G17.035', 'L01.224.050'], ['G16.500.275.063', 'N06.230.300.100'], ['L01.224.160'], ['G01.060.185', 'G01.750.750.235', 'G16.500.200', 'N06.230.300.100.300'], ['E05.599'], ['G01.249.660.250'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['E05.799.638', 'N06.850.780.375.700', 'N06.850.810.370'], ['E05.196.867']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Mechanism for inactivation of the mitotic inhibitory kinase Wee1 at M phase. | Wee1, the inhibitory kinase of cyclin B/Cdc2, undergoes a phosphorylation-dependent catalytic inactivation at M phase of the mitotic cell cycle, but the precise mechanism for this inactivation is not known. Using Xenopus egg and extract systems, we show here that the kinase activity of Xenopus somatic Wee1 (XeWee1B) is... | ['Amino Acid Motifs', 'Amino Acid Sequence', 'Animals', 'Catalytic Domain', 'Cell Cycle Proteins', 'Cell Division', 'Gene Expression Regulation', 'Insecta', 'Mitosis', 'Molecular Sequence Data', 'NIMA-Interacting Peptidylprolyl Isomerase', 'Oocytes', 'Peptidylprolyl Isomerase', 'Phosphorylation', 'Protein Binding', 'Pr... | 17,360,425 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D12.776.167'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G05.308'], ['B01.050.500.131.617'], ['G04.144... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
'Poor me' versus 'bad me' paranoia and the instability of persecutory ideation. | OBJECTIVES: To investigate whether there are two stable types of paranoia, 'poor me' and 'bad me', as described by Trower and Chadwick (1995), and whether beliefs about the deservedness of persecution are associated with psychological measures.METHODS: In-patients experiencing persecutory delusions were assigned either... | ['Adult', 'Delusions', 'Family', 'Female', 'Humans', 'Individuality', 'Male', 'Object Attachment', 'Paranoid Disorders', 'Personality Tests', 'Psychiatric Status Rating Scales', 'Psychotic Disorders', 'Schizophrenic Psychology', 'Self Concept'] | 16,774,723 | [['M01.060.116'], ['F01.145.126.200'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.488'], ['F02.739.794.624'], ['F03.700.450'], ['F04.711.647'], ['F04.711.513.653'], ['F03.700.675'], ['F04.824'], ['F01.752.747.792']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Magnetic Resonance Imaging of the Lung as an Alternative for a Pregnant Woman with Pulmonary Tuberculosis. | We report a case of a pregnant 21-year-old woman with pulmonary tuberculosis in which magnetic resonance imaging of the lung was used to assess the extent and characteristics of the pathological changes. Although the lung has been mostly ignored in magnetic resonance imaging for many decades, today technical developmen... | ['Antitubercular Agents', 'Diagnosis, Differential', 'Female', 'Humans', 'Lung', 'Magnetic Resonance Imaging', 'Pregnancy', 'Treatment Outcome', 'Tuberculosis, Pulmonary', 'Young Adult'] | 26,622,928 | [['D27.505.954.122.085.255'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['E01.370.350.825.500'], ['G08.686.784.769'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['C01.150.252.410.040.552.846.899', 'C01.748.939', 'C08.381.922', 'C08.730.939'], ['M01.060.116.815']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Thinking of something to say: public and private narratives of infertility. | Autobiographical narratives of infertility are situated in both the private and public domains, particularly since the advent of assisted reproductive technology. Narratives of infertility told by 31 Australian women reveal that the tension between the public and the private is an uncomfortable one for the narrators. I... | ['Communication', 'Female', 'Humans', 'Infertility, Female', 'Interpersonal Relations', 'Privacy'] | 12,141,845 | [['F01.145.209', 'L01.143'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['F01.829.401'], ['I01.880.604.473.352.500', 'N03.706.437.352.500', 'N03.706.615.862']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Synthesis of novel 2'-deoxy type trans-3',4'-bridged nucleic acid. | We newly designed and synthesized a 2'-deoxy type trans-3',4'-bridged nucleic acid (trans-3',4'-BNA) analogues bearing a 4,7-dioxabicyclo[4.3.0]nonane structure. The synthesis of the trans-3',4'-BNA was carried out successfully from thymidine over 21 steps. The structure of trans-3',4'-BNA was confirmed by x-ray crysta... | ['Bridged Bicyclo Compounds', 'Crystallography, X-Ray', 'Deoxyribonucleosides', 'Drug Design', 'Methods', 'Molecular Conformation', 'Molecular Structure', 'Stereoisomerism'] | 18,058,540 | [['D02.455.426.100.080', 'D04.075.080'], ['E05.196.309.742.225'], ['D13.570.230'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['E05.581'], ['G02.111.570.820'], ['G02.111.570', 'G02.466'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Combined bromocriptine-levodopa therapy early in Parkinson's disease. | Compared with levodopa, treatment of parkinsonism for 3 years with bromocriptine alone resulted in less fluctuation and peak-dose dyskinesia, but also less improvement in parkinsonian disability. Only a few of the 76 patients had long-term benefit on chronic bromocriptine therapy. However, combined bromocriptine and le... | ['Bromocriptine', 'Disability Evaluation', 'Dose-Response Relationship, Drug', 'Drug Combinations', 'Female', 'Humans', 'Levodopa', 'Male', 'Middle Aged', 'Parkinson Disease', 'Time Factors'] | 4,022,354 | [['D03.132.327.412.100', 'D03.633.400.439.131', 'D03.633.400.562.100'], ['E01.370.400'], ['G07.690.773.875', 'G07.690.936.500'], ['D26.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.311.200.480', 'D02.455.426.559.389.657.166.175.200.480', 'D12.125.072.050.685.400.500', 'D12.125.072.050.875.130.500'],... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evolutionary history of the vertebrate period genes. | Circadian clock genes are remarkably conserved between eucoelomates. Although Drosophila has one copy of each major component, vertebrates have two or (in the case of the Period genes) three paralogs (Per1-3). We investigated the possibility that the vertebrate Per genes arose through two genome duplications during the... | ['Alternative Splicing', 'Animals', 'Biological Clocks', 'Conserved Sequence', 'Drosophila', 'Evolution, Molecular', 'Exons', 'Eye Proteins', 'Gene Duplication', 'Humans', 'Nuclear Proteins', 'Period Circadian Proteins', 'Phylogeny', 'Transcription Factors', 'Zebrafish', 'Zebrafish Proteins'] | 16,752,210 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['B01.050'], ['G07.180.562.094'], ['G02.111.570.580'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.024.340.137.232'], ['D12.776.306'], ['G05.365.590.320', 'G05.558.320'], ['B01.050.150.900.649.313.988.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A human monoclonal antibody which inhibits the coaggregation activity of Porphyromonas gingivalis. | A B-cell line producing a human monoclonal antibody (HuMAb) against a recombinant 40-kDa outer membrane protein (OMP) of Porphyromonas gingivalis was constructed by in vivo immunization of a severe combined immunodeficiency C.B.-17/Icr mouse, which had been injected with human peripheral blood lymphocytes, with recombi... | ['Animals', 'Antibodies, Bacterial', 'Antibodies, Monoclonal', 'Antigens, Bacterial', 'Bacterial Adhesion', 'Bacterial Outer Membrane Proteins', 'Cell Transformation, Viral', 'Herpesvirus 4, Human', 'Humans', 'Mice', 'Mice, SCID', 'Porphyromonas gingivalis', 'Recombinant Proteins'] | 9,284,182 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.161'], ['G06.099.050'], ['D12.776.097.120', 'D12.776.543.100'], ['C04.697.098.500.160', 'C23.550.727.098.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitation of the release of doxorubicin from colloidal dosage forms using dynamic dialysis. | The release of doxorubicin from submicrometer bovine serum albumin (BSA) microspheres has been quantitated using dynamic dialysis. Mathematical models have been proposed based on zero- or first-order release of drug from solid colloidal matrices. The models also account for the permeability constant of the dialysis mem... | ['Colloids', 'Delayed-Action Preparations', 'Dialysis', 'Doxorubicin', 'Kinetics', 'Microspheres', 'Models, Chemical', 'Serum Albumin, Bovine', 'Solubility'] | 3,572,752 | [['D20.280', 'D26.255.165'], ['D26.255.210', 'E02.319.300.253'], ['E05.196.353', 'G02.186'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['G01.374.661', 'G02.111.490'], ['E07.565'], ['E05.599.495'], ['D12.776.034.841.540', 'D12.776.124.727.875'], ['G02.805']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pulmonary contusion is associated with toll-like receptor 4 upregulation and decreased susceptibility to pseudomonas pneumonia in a mouse model. | Pulmonary contusion is a major cause of respiratory failure in trauma patients. This injury frequently leads to immune suppression and infectious complications such as pneumonia. The mechanism whereby trauma leads to an immune-suppressed state is poorly understood. To further study this phenomenon, we developed an anim... | ['Animals', 'Bronchoalveolar Lavage Fluid', 'Disease Susceptibility', 'Flow Cytometry', 'Hypersensitivity, Delayed', 'Lung Injury', 'Male', 'Mice', 'Mice, Inbred Strains', 'Pneumonia, Bacterial', 'Pseudomonas Infections', 'Pseudomonas aeruginosa', 'Toll-Like Receptor 2', 'Toll-Like Receptor 4', 'Up-Regulation'] | 22,392,148 | [['B01.050'], ['E05.927.100.500'], ['C23.550.291.687', 'G07.100.250'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['C20.543.418'], ['C08.381.520', 'C26.891.554'], ['B01.050.150.900.649.313.992... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interventions to promote healthy environments in family child care homes in Oklahoma-Happy Healthy Homes: study protocol for a randomized controlled trial. | BACKGROUND: Early childhood is a critical period of development. Caregivers, including providers of early care and education (ECE), have a substantial influence on the health of young children. Family child care homes (FCCHs), which are small, licensed ECE businesses operated out of the residences of providers, are imp... | ['Child', 'Child Care', 'Environmental Health', 'Family', 'Happiness', 'Humans', 'Outcome Assessment, Health Care', 'Randomized Controlled Trials as Topic'] | 31,470,886 | [['M01.060.406'], ['I01.880.787.293.360', 'N02.421.088'], ['H02.229'], ['F01.829.263', 'I01.880.853.150'], ['F01.470.516'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Motor paresis improved by sympathetic block. A motor form of reflex sympathetic dystrophy? | Four patients had a characteristic motor paresis that was dramatically improved by sympathetic block. The cause of this paresis could not be determined by the usual neurological examinations. It was similar to reflex sympathetic dystrophy in that the patients experienced severe pain, swelling, coldness, and muscle atro... | ['Adult', 'Autonomic Nerve Block', 'Blepharoptosis', 'Blood Pressure', 'Epinephrine', 'Female', 'Humans', 'Male', 'Middle Aged', 'Muscles', 'Paralysis', 'Reflex Sympathetic Dystrophy'] | 2,730,381 | [['M01.060.116'], ['E03.155.086.711.299', 'E04.525.210.550.500'], ['C11.338.204'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparing the utility of 30- and 60-minute cortisol levels after the standard short synacthen test to determine adrenal insufficiency: A retrospective cross-sectional study. | Short Synacthen test (SST) involves measuring the baseline, 30-, and 60-minute serum cortisol levels, after injecting 250 ìg of synthetic adrenocorticotropic hormone or Synacthen (ACTH). This study aimed to review the current clinical practice of performing SST to establish a standardized test protocol and to additiona... | ['Adrenal Insufficiency', 'Adult', 'Aged', 'Cross-Sectional Studies', 'False Positive Reactions', 'Female', 'Humans', 'Hydrocortisone', 'Male', 'Middle Aged', 'Reproducibility of Results', 'Retrospective Studies', 'Time Factors'] | 33,120,750 | [['C19.053.500'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.354.506'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['M01.060.116.630'], ['E05.318.3... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In vitro and in vivo antitumor activity of benzyl isothiocyanate: a natural product from Tropaeolum majus. | Cultured cells of Tropaeolum majus produce significant amounts of benzyl glucosinolate which, through enzymatic hydrolysis, results in the production of benzyl isothiocyanate (BITC). This study reports on the in vitro anticancer properties of BITC against a variety of human and murine tumor cell lines by four independe... | ['Animals', 'Antineoplastic Agents', 'Cell Line', 'Female', 'Humans', 'Isothiocyanates', 'Leukemia L1210', 'Lung Neoplasms', 'Mice', 'Mice, Inbred BALB C', 'Ovarian Neoplasms', 'Plants, Medicinal', 'Plasmacytoma', 'Tumor Cells, Cultured', 'Tumor Stem Cell Assay'] | 7,617,765 | [['B01.050'], ['D27.505.954.248'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.500.375', 'D02.886.250'], ['C04.557.337.372.594', 'C04.619.531.594'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.15... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Older Mexican-American women and cancer screening: progress toward targets for healthy people 2000. | BACKGROUND: Published information about cancer screening in older Mexican-American women is scarce. This study reported the patterns of mammogram and Pap test use among older Mexican-American women. The patterns and associated factors were examined and compared with Healthy People 2000 targets.METHODS: Data were obtain... | ['Aged', 'Female', 'Humans', 'Mammography', 'Mass Screening', 'Mexican Americans', 'Neoplasms', 'Risk Factors', 'Southwestern United States', 'Vaginal Smears'] | 11,763,289 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500'], ['M01.686.754.441.500'], ['C04'], ['E05.318.740.600.800.725', 'N05.715.350.2... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Spatial rotational alignment of identical particles in the case of (almost) coaxial projections. | Knowledge of projection directions is essential to the 3D reconstruction of biological objects from electron micrographs. In the general case, mutual orientation of the particles lying randomly on a support film can be found by the geometrical method described elsewhere. In the case of coaxial projections, the geometri... | ['Computers', 'Mathematics', 'Microscopy, Electron', 'Proteins', 'Ribosomes'] | 2,749,921 | [['L01.224.230.260'], ['H01.548'], ['E01.370.350.515.402', 'E05.595.402'], ['D12.776'], ['A11.284.430.214.190.875.811']] | ['Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Aspects of the testicular toxicity of phthalate esters. | Di(2-ethylhexyl) phthalate (DEHP) produced seminiferous tubular atrophy and reductions in seminal vesicle and prostate weight in 4-week-old, but not in 15-week-old rats. Di-n-pentyl phthalate (DPP) did produce atrophy in the older rats but this developed more slowly than in young animals. Coadministration of testostero... | ['Age Factors', 'Androgen-Binding Protein', 'Animals', 'Cells, Cultured', 'Gonadotropins, Equine', 'Male', 'Organ Size', 'Phthalic Acids', 'Rats', 'Seminiferous Tubules', 'Sertoli Cells', 'Spermatocytes', 'Spermatogonia', 'Testis'] | 3,709,446 | [['N05.715.350.075', 'N06.850.490.250'], ['D12.776.157.065'], ['B01.050'], ['A11.251'], ['D06.472.699.322.451', 'D06.472.699.649.451', 'D12.644.548.726.451', 'D12.776.780.451'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690'], ['D02.241.223.805'], ['B01.050.150.900.649.313.992.635.5... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Can noncontrast helical computed tomography replace intravenous urography for evaluation of patients with acute urinary tract colic? | The objective of this study was to determine whether helical computed tomography (CT) performed without oral or intravenous contrast agents is accurate in the evaluation of patients with suspected acute renal colic. One hundred consecutive patients with suspected renal colic or ureteral colic were referred by our insti... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Colic', 'Humans', 'Kidney Calculi', 'Middle Aged', 'Sensitivity and Specificity', 'Technology Assessment, Biomedical', 'Tomography, X-Ray Computed', 'Ureteral Calculi', 'Urography', 'Urologic Diseases'] | 10,195,491 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['C16.614.166'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.600.500', 'C12.777.967.249.500', 'C12.777.967.500.503', 'C13.351.968.419.600.500', 'C13.351.968.967.249.500', 'C13.351.96... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Polymorphic oxidation of debrisoquine in lung cancer patients. | Oxidative polymorphism of debrisoquine (DBQ) was assessed in 84 patients (81 male) with histologically proven bronchogenic carcinoma and in 143 healthy male smokers. 80 (95%) patients and 133 (93%) controls, with a metabolic ratio (MR) below 12.6, were classified as extensive metabolisers of DBQ (no significant differe... | ['Aged', 'Carcinoma, Bronchogenic', 'Debrisoquin', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Oxidation-Reduction', 'Polymorphism, Genetic', 'Risk Factors', 'Smoking'] | 1,827,280 | [['M01.060.116.100'], ['C04.588.894.797.520.109.220', 'C08.381.540.140', 'C08.785.520.100.220'], ['D03.633.100.531.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['G02.700', 'G03.295.531'], ['G05.365.795'], ['E05.318.740.600.800.725', ... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Graves' ophthalmopathy: low-dose dexamethasone reduces retinoic acid receptor-alpha gene expression in orbital fibroblasts. | OBJECTIVE: Graves' ophthalmopathy (GO) is an autoimmune disease that leads to ocular proptosis caused by fat accumulation and inflammation, and the main treatment is corticosteroid therapy. Retinoid acid receptor-alpha (RARá) seems to be associated with inflammation and adipocyte differentiation. This study aimed to as... | ['Dexamethasone', 'Fibroblasts', 'Gene Expression', 'Glucocorticoids', 'Graves Ophthalmopathy', 'Humans', 'Orbit', 'Retinoic Acid Receptor alpha', 'Severity of Illness Index'] | 29,791,662 | [['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['A11.329.228'], ['G05.297'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['C11.270.240', 'C11.675.349.500.500', 'C16.320.347', 'C19.874.283.605.500', 'C19.874.397.370.500', 'C20.111.555.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.78... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Association between Bmi1 and clinicopathological status of esophageal squamous cell carcinoma. | AIM: To investigate the clinicopathological roles of Bmi1 in esophageal squamous cell carcinoma (ESCC).METHODS: Quantitative real-time polymerase chain reaction and immunohistochemical staining for Bmi1 were performed in cancerous and adjacent non-cancerous paraffin-embedded esophageal specimens.RESULTS: The Bmi1 expre... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Squamous Cell', 'Esophageal Neoplasms', 'Esophagus', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nuclear Proteins', 'Polycomb Repressive Complex 1', 'Polymerase Chain Reaction', 'Proto-Oncogene Proteins', 'Repressor Proteins'] | 19,452,584 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['A03.556.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D12.776.660'],... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Simultaneous analysis of prednisone, prednisolone and their major hydroxylated metabolites in urine by high-performance liquid chromatography. | A high-performance liquid chromatographic technique for the simultaneous determination of prednisone, prednisolone and their major hydroxylated metabolites, viz., 20 beta-hydroxyprednisone, 6 beta-, 20 alpha- and 20 beta-hydroxyprednisolone, in human urine is presented. The retention times were 6.5, 11.4, 18.1, 24.2, 3... | ['Chromatography, High Pressure Liquid', 'Humans', 'Hydroxylation', 'Male', 'Prednisolone', 'Prednisone', 'Spectrophotometry, Ultraviolet'] | 1,918,259 | [['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.385', 'G02.607.348', 'G03.425'], ['D04.210.500.745.432.769.795'], ['D04.210.500.745.432.719.702'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of a 48-h fast on heart rate variability and cortisol levels in healthy female subjects. | BACKGROUND/OBJECTIVES: The physiological changes that occur during fasting are not completely understood, regardless of the cause for fasting (for example, medical, lifestyle, religious, political or famine). The purpose of this study was to examine the effects of a 48-h fast on heart rate variability (HRV) and cortiso... | ['Adolescent', 'Adult', 'Body Mass Index', 'Body Weight', 'Fasting', 'Female', 'Heart Rate', 'Humans', 'Hydrocortisone', 'Linear Models', 'Rest', 'Young Adult'] | 23,403,876 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['E01.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Topographical projections from the medial septum-diagonal band complex to the hippocampus: a retrograde tracing study with multiple fluorescent dyes in rats. | Direct projections from the medial septum-diagonal band complex (MS-DB) to the hippocampus were studied in rats using the retrograde labeling method with fluorescent dyes. In the first series of experiments, the distribution patterns of retrogradely labeled cells in the MS-DB were examined in sagittal sections, followi... | ['Animals', 'Brain', 'Fluorescent Dyes', 'Hippocampus', 'Histocytochemistry', 'Male', 'Nerve Fibers', 'Neural Pathways', 'Rats', 'Rats, Wistar', 'Spinal Cord'] | 7,753,501 | [['B01.050'], ['A08.186.211'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['A08.675.542', 'A11.671.501'], ['... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Biosynthetic incorporation of [3H]ethanolamine into protein synthesis elongation factor 1 alpha reveals a new post-translational protein modification. | Biosynthetic incorporation of [3H]ethanolamine into proteins was assessed in the human erythroleukemia cell line K562. A single predominant labeled protein of about 50 kDa was observed following electrophoresis of cell extracts on polyacrylamide gels in the presence of sodium dodecyl sulfate. Subcellular fractionation ... | ['Animals', 'Blotting, Western', 'Electrophoresis, Gel, Two-Dimensional', 'Ethanolamine', 'Ethanolamines', 'Humans', 'In Vitro Techniques', 'Isoelectric Point', 'Molecular Weight', 'Peptide Elongation Factor 1', 'Peptide Elongation Factors', 'Peptide Fragments', 'Protein Processing, Post-Translational', 'Rabbits', 'Sub... | 2,708,357 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.196.401.250', 'E05.301.300.230'], ['D02.033.100.291.375', 'D02.033.375.291.375', 'D02.092.063.291.375'], ['D02.033.100.291', 'D02.033.375.291', 'D02.092.063.291'], ['B01.050.150.900.649.313.988.400.1... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comparative study on the efficacy of 10% hypertonic saline and equal volume of 20% mannitol in the treatment of experimentally induced cerebral edema in adult rats. | BACKGROUND: Hypertonic saline and mannitol are commonly used in the treatment of cerebral edema and elevated intracranial pressure (ICP) at present. In this connection, 10% hypertonic saline (HS) alleviates cerebral edema more effectively than the equal volume of 20% mannitol. However, the exact underlying mechanism fo... | ['Animals', 'Brain Edema', 'Disease Models, Animal', 'Infarction, Middle Cerebral Artery', 'Male', 'Mannitol', 'Osmotic Pressure', 'Rats', 'Rats, Sprague-Dawley', 'Saline Solution, Hypertonic'] | 21,143,951 | [['B01.050'], ['C10.228.140.187'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.228.140.300.150.477.200.450', 'C10.228.140.300.510.200.387', 'C10.228.140.300.775.200.200.450', 'C14.907.253.092.477.200.450', 'C14.907.253.560.200.387', 'C14.907.253.855.200.200.450', 'C23.550.513.355.250.200.450', 'C23.550.717.489... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reduction of free radicals in multiple sclerosis: effect of glatiramer acetate (Copaxone). | Free radicals have been found in high concentrations within inflammatory multiple sclerosis (MS) lesions. The superoxide anion (O(2)(-)) reacts rapidly with nitric oxide (NO), producing peroxynitrite (ONOO(-)). Glatiramer acetate (GA) is a specific MS immunomodulator that induces the synthesis of Th2 cytokines, and red... | ['Adult', 'Cells, Cultured', 'Female', 'Free Radicals', 'Glatiramer Acetate', 'Humans', 'Immunosuppressive Agents', 'Leukocytes, Mononuclear', 'Lipopolysaccharides', 'Male', 'Middle Aged', 'Multiple Sclerosis, Relapsing-Remitting', 'Nitric Oxide', 'Nitric Oxide Synthase Type II', 'Oxidative Stress', 'Peptides', 'Supero... | 18,505,779 | [['M01.060.116'], ['A11.251'], ['D01.339', 'D02.389'], ['D12.644.219'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.490.555'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['M01.060.116.630'... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The relationship between gastro-oesophageal reflux symptoms and achalasia. | BACKGROUND AND AIMS: Patients with achalasia can experience heartburn, which may be misinterpreted as gastro-oesophageal reflux disease (GORD), leading to a delay in diagnosis and subsequent treatment. We investigated the relationship between gastro-oesophageal reflux (GOR) and reflux symptoms in a large cohort of pati... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Diagnosis, Differential', 'Esophageal Achalasia', 'Female', 'Gastroesophageal Reflux', 'Heartburn', 'Humans', 'Male', 'Manometry', 'Middle Aged', 'Retrospective Studies'] | 16,538,107 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['E01.171'], ['C06.405.117.119.500.432'], ['C06.405.117.119.500.484'], ['C23.888.821.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.559'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.75... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evolution and genetic architecture of chromatin accessibility and function in yeast. | Chromatin accessibility is an important functional genomics phenotype that influences transcription factor binding and gene expression. Genome-scale technologies allow chromatin accessibility to be mapped with high-resolution, facilitating detailed analyses into the genetic architecture and evolution of chromatin struc... | ['Biological Evolution', 'Chromatin', 'Chromosome Mapping', 'Chromosome Structures', 'Gene Expression Regulation', 'Phenotype', 'Promoter Regions, Genetic', 'Protein Biosynthesis', 'Regulatory Elements, Transcriptional', 'Saccharomyces cerevisiae', 'Transcription Factors'] | 24,992,477 | [['G05.045', 'G16.075'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['E05.393.183'], ['A11.284.430.106.279.345.190.160', 'G05.360.160'], ['G05.308'], ['G05.695'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['G02.111.660.871', 'G03.734.871',... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gaze and retinal-image-stability in two kinds of sequential looking tasks. | UNLABELLED: Eye and head movements used to keep the gaze on target were examined as unrestrained seated subjects performed two tasks: (1) tapping sequences of 3-D targets; and (2) only looking at sequences of 3-D targets. Large differences were observed in the head/eye coordination patterns used in each task. During ta... | ['Algorithms', 'Eye Movements', 'Fixation, Ocular', 'Head Movements', 'Humans', 'Psychophysics', 'Retina', 'Time Factors'] | 9,893,806 | [['G17.035', 'L01.224.050'], ['G11.427.410.140', 'G14.350'], ['G14.350.253'], ['G11.427.410.478'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.685', 'F04.096.753'], ['A09.371.729'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
DNA sequences showing a delay in cytosine methylation after replication. Time course of methylation in synchronized mammalian cell populations and relationship to DNAase I sensitive domains. | We have shown that in several mammalian cell lines a minor fraction of cytosine methylation is delayed for up to several hours after strand synthesis and that different methylases performed the immediate and the delayed classes of DNA methylation. To investigate the time course of this delayed methylation we have used ... | ['Animals', 'Cell Line', 'Cricetinae', 'Cricetulus', 'Cytosine', 'DNA', 'DNA (Cytosine-5-)-Methyltransferases', 'DNA Replication', 'DNA, Neoplasm', 'Deoxyribonuclease I', 'Endodeoxyribonucleases', 'Female', 'Flow Cytometry', 'Humans', 'Kinetics', 'Leukemia, Lymphoid', 'Methionine', 'Methylation', 'Ovary'] | 6,225,463 | [['B01.050'], ['A11.251.210'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['D03.383.742.698.421'], ['D13.444.308'], ['D08.811.913.555.500.350.100.500'], ['G02.111.225', 'G05.226'], ['D13.444.308.425'], ['D08.811.277.352.335.350.250'], ['D08.811.277.352.335.350', 'D08.8... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human identification through frontal sinus 3D superimposition: Pilot study with Cone Beam Computer Tomography. | As a unique anatomical feature of the human body, the frontal sinus morphology has been used for identification of unknown bodies with many techniques, mostly using 2D postero-anterior X-rays. With the increase of the use of Cone-Beam Computer Tomography (CBCT), the availability of this exam as ante-mortem records shou... | ['Adult', 'Cone-Beam Computed Tomography', 'Female', 'Forensic Anthropology', 'Frontal Sinus', 'Humans', 'Imaging, Three-Dimensional', 'Male', 'Pilot Projects', 'Reproducibility of Results', 'Software', 'Young Adult'] | 26,408,391 | [['M01.060.116'], ['E01.370.350.700.810.810.490', 'E01.370.350.825.810.810.399'], ['I01.076.368.400', 'I01.198.780.750'], ['A04.531.621.387'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E05.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Psychiatric history modifies the gender ratio of suicide: an East and West comparison. | OBJECTIVE: Gender ratios of suicide rates differ greatly across countries. Victoria has a high male:female ratio in suicide that is typical in English-speaking and European countries, while in Hong Kong the low ratio is similar to other SouthEast Asian countries. This study investigates the effect of gender in the psyc... | ['Cross-Cultural Comparison', 'Data Collection', 'Female', 'Hong Kong', 'Humans', 'Male', 'Mental Disorders', 'Prevalence', 'Sex Distribution', 'Suicide', 'Victoria'] | 18,661,085 | [['I01.076.201.450.281', 'I01.880.853.100.257'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['Z01.252.474.164.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['I0... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Hydrodynamic drag on non-spherical floc and free-settling test. | This work numerically investigates the hydrodynamic drag force exerted on a porous spheroid floc moving steadily through a quiescent Newtonian fluid over a wide range of the Reynolds number. The flow patterns for a highly porous spheroid moving at an elevated Reynolds number are basically the same as those at a low Rey... | ['Flocculation', 'Friction', 'Mathematics', 'Oxygen', 'Particle Size', 'Sewage', 'Solutions'] | 11,487,120 | [['E05.196.150.347', 'G02.159.347'], ['G01.374.618'], ['H01.548'], ['D01.268.185.550', 'D01.362.670'], ['G02.712'], ['D20.944.932.500'], ['D26.776']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Estimating Aquifer Properties Using Derivative Analysis of Water Level Time Series from Active Well Fields. | Water level time series from groundwater production wells offer a transient dataset that can be used to estimate aquifer properties in areas with active groundwater development. This article describes a new parameter estimation method to infer aquifer properties from such datasets. Specifically, the method analyzes lon... | ['Colorado', 'Groundwater', 'Water', 'Water Movements', 'Water Supply'] | 26,340,251 | [['Z01.107.567.875.760.210'], ['G01.311.355'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925'], ['G16.500.971', 'N06.230.132.644.750', 'N06.230.850'], ['J01.293.821.500']] | ['Geographicals [Z]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Hemangiopericytoma of the tongue: report of case. | A case of hemangiopericytoma of the tongue is reported. A comprehensive literature review regarding hemangiopericytoma of the tongue has been presented. Only ten cases of hemangiopericytoma of the tongue have been reported in the literature, including the present case, a 29-year-old male. | ['Adult', 'Cytoplasm', 'Hemangiopericytoma', 'Humans', 'Male', 'Organoids', 'Tongue Neoplasms'] | 6,592,243 | [['M01.060.116'], ['A11.284.430.214'], ['C04.557.645.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.802'], ['C04.588.443.591.925', 'C07.465.530.925', 'C07.465.910.470']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pseudomonas poae-Associated Fatal Septic Transfusion Reaction, Peoria, Illinois, USA, 2017. | In the United States, fatal transfusion-transmitted infections from red blood cell units are rare. Although this pattern mostly reflects how inhospitable refrigerated red blood cell units are to contaminant growth, fatalities caused by microorganisms that can grow at storage temperature (4°C), but not in standard clini... | ['Blood Transfusion', 'Erythrocyte Transfusion', 'Fatal Outcome', 'Female', 'Humans', 'Illinois', 'Middle Aged', 'Multilocus Sequence Typing', 'Phylogeny', 'Pseudomonas', 'Pseudomonas Infections', 'RNA, Ribosomal, 16S', 'Sepsis', 'Transfusion Reaction'] | 31,310,217 | [['E02.095.135'], ['E02.095.135.140.275'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.350.350', 'Z01.107.567.875.510.350'], ['M01.060.116.630'], ['E01.370.225.875.150.125.457.500', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Validity and power of association testing in family-based sampling designs: evidence for and against the common wisdom. | Current common wisdom posits that association analyses using family-based designs have inflated type 1 error rates (if relationships are ignored) and independent controls are more powerful than familial controls. We explore these suppositions. We show theoretically that family-based designs can have deflated type-error... | ['Analysis of Variance', 'Case-Control Studies', 'Family', 'Female', 'Genome-Wide Association Study', 'Humans', 'Likelihood Functions', 'Male', 'Models, Genetic', 'Models, Statistical', 'Molecular Epidemiology', 'Pedigree', 'Reproducibility of Results'] | 21,328,615 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['F01.829.263', 'I01.880.853.150'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Premature vertebral endplate ossification and mild disc degeneration in mice after inactivation of one allele belonging to the Col2a1 gene for Type II collagen. | STUDY DESIGN: Skeletal tissues of mice with an inactivated allele of the Col2a1 gene for Type II collagen ("heterozygous knockout") were studied.OBJECTIVE: To determine whether a heterozygous inactivation of the Col2a1 gene has a role in the etiology of spine disorders such as disc degeneration.SUMMARY OF BACKGROUND DA... | ['Aging', 'Alleles', 'Animals', 'Bone and Bones', 'Collagen Type II', 'Gene Silencing', 'Glycosaminoglycans', 'Heterozygote', 'Intervertebral Disc', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Motor Activity', 'Ossification, Heterotopic', 'Radiography', 'Reference Values', 'Skull', 'Spinal Diseases', 'Spine', 'Tis... | 11,725,236 | [['G07.345.124'], ['G05.360.340.024.340.030'], ['B01.050'], ['A02.835.232', 'A10.165.265'], ['D05.750.078.280.300.200', 'D12.776.860.300.250.300.200'], ['G05.308.203.374'], ['D09.698.373'], ['G05.380.383'], ['A02.165.308.410', 'A02.835.232.834.432', 'A10.165.382.350.050'], ['B01.050.150.900.649.313.992.635.505.500'], [... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative uptake, retention and action of vincristine, vinblastine and vindesine on murine leukaemic lymphoblasts sensitive and resistant to vincristine. | 1. The uptake and retention of vincristine (VCR), vinblastine (VBL) and vindesine (VDS) were evaluated comparatively with respect to their cytotoxic action on a murine lymphoblastic leukaemia (L5178Y). 2. The same parameters were measured on a derived subline of cells resistant to VCR (L5178Y/r) in order to determine w... | ['Animals', 'Body Water', 'Drug Resistance', 'Leukemia L5178', 'Leukemia, Experimental', 'Lymphocytes', 'Mice', 'Tumor Cells, Cultured', 'Vinblastine', 'Vinca Alkaloids', 'Vincristine', 'Vindesine'] | 3,390,658 | [['B01.050'], ['A12.207.200'], ['G07.690.773.984'], ['C04.557.337.372.602', 'C04.619.531.602'], ['C04.557.337.372', 'C04.619.531', 'E05.598.500.496.500'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.251.860'], ['D03.132.436.681.827.650', ... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prospective analysis of the use of OnabotulinumtoxinA (BOTOX) in the treatment of chronic migraine; real-life data in 254 patients from Hull, U.K. | BACKGROUND: Chronic migraine affects 2% of the population. It results in substantial disability and reduced quality of life. Medications used for prophylaxis in episodic migraine may also work in chronic migraine. The efficacy and safety of OnabotulinumtoxinA (BOTOX) in adults with chronic migraine was confirmed in the... | ['Adult', 'Aged', 'Analgesics', 'Botulinum Toxins, Type A', 'Chronic Disease', 'Female', 'Humans', 'Male', 'Middle Aged', 'Migraine Disorders', 'Prospective Studies', 'Quality of Life', 'Treatment Outcome', 'Young Adult'] | 25,178,393 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.140.546.39... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Effect of inpatient versus outpatient measurement protocol on resting metabolic rate and respiratory exchange ratio. | Resting metabolic rate (RMR) and respiratory exchange ratio (RER) were measured, using indirect calorimetry, in 9 healthy, male subjects (28.6 +/- 3.3 years) under three conditions: (1) an inpatient, meal-controlled protocol (IPM) in which subjects were fed an evening meal and slept overnight in the laboratory prior to... | ['Adult', 'Ambulatory Care', 'Analysis of Variance', 'Basal Metabolism', 'Body Composition', 'Calorimetry, Indirect', 'Diet', 'Hospitalization', 'Humans', 'Male', 'Pulmonary Gas Exchange'] | 8,470,869 | [['M01.060.116'], ['E02.760.106', 'N02.421.585.106'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G03.295.154'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E05.196.131.655'], ['G07.203.650.240'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.38... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Elaboration of ammonio methacrylate copolymer based spongy cationic particles via double emulsion solvent evaporation process. | The aim of present work is to investigate systematic study of the preparation of biodegradable particles via double emulsion solvent evaporation technique. The used formation is based on cationic ammonium methacrylate copolymer Eudragit® RS 100, without the use of any stabilizer. The effect of process parameters like u... | ['Acrylic Resins', 'Ammonium Compounds', 'Biodegradable Plastics', 'Methacrylates'] | 26,838,828 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['D01.625.062'], ['D05.750.716.195', 'D25.720.716.195', 'J01.637.051.720.716.195'], ['D02.241.081.069.600']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Radiographic absorptiometry: a simple method for determination of bone mass. | Bone mass measurements have been shown to be useful determinants of the risk of development of osteoporotic fractures and may help identify individuals who are most likely to benefit from both primary and secondary prevention of osteoporosis. As standard bone density measurements are not available to all physicians, th... | ['Absorptiometry, Photon', 'Bone Density', 'Bone and Bones', 'Female', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests'] | 1,790,418 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['G11.427.100'], ['A02.835.232', 'A10.165.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enhancement of stent-induced thromboembolism by residual stenoses: contribution of hemodynamics. | In vitro stent-induced thromboembolism was altered by the presence of residual stenoses placed upstream or placed upstream and downstream of the stent. Heparinized (3 micro/ml) bovine blood was gravity fed through a conduit with a deployed coronary stent. Embolism was continuously monitored using a light-scattering mic... | ['Animals', 'Blood Flow Velocity', 'Cattle', 'Computer Simulation', 'Constriction, Pathologic', 'Hemodynamics', 'Models, Cardiovascular', 'Stents', 'Stress, Mechanical', 'Thromboembolism', 'Viscosity'] | 10,710,190 | [['B01.050'], ['E01.370.370.130', 'G09.330.380.630.080'], ['B01.050.150.900.649.313.500.380.271'], ['L01.224.160'], ['C23.300.287'], ['G09.330.380'], ['E05.599.395.161'], ['E07.695.750'], ['G01.374.835'], ['C14.907.355.590'], ['G02.930']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Frequency of sex chromosome nondisjunction as affected by microtubule destabilization and heat shock in various lines of Drosophila melanogaster]. | Vinblastine (Vb), a drug belonging to a group of mitotic poisons, was shown to induce sexual chromosome nondisjunction and loss (SCNL) in oogenesis of different strains of Drosophila melanogaster. Heat shock (37 degrees C, 45 min) decreases the frequency of these events. The highest level of nondisjunction was demonstr... | ['Animals', 'Colchicine', 'Drosophila melanogaster', 'Female', 'Griseofulvin', 'Heat-Shock Response', 'Microtubules', 'Mitosis', 'Nondisjunction, Genetic', 'Oogenesis', 'Sex Chromosomes', 'Species Specificity', 'Vinblastine'] | 10,519,067 | [['B01.050'], ['D03.132.225'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['D03.633.100.127.275'], ['G07.775.500'], ['A11.284.430.214.190.750.602'], ['G04.144.220.220.781', 'G05.113.220.781'], ['C23.550.210.645', 'G05.113.220.625.620', 'G05.558.620'], ['G04.152.650.249', 'G08.686.784.310.500'], ['A11.284.187.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evolution of sensitivity to Hymenoptera venom in 200 allergic patients followed for up to 3 years. | Duration of venom immunotherapy still remains questionnable, since some patients outgrow their sensitivity. Two hundred venom-allergic patients (4 to 82 years; mean +/- SD, 37.3 +/- 14.2 years) who were first observed with systemic reactions (SRs) were investigated yearly for up to 3 years. Among these patients, 72 wer... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Animals', 'Bee Venoms', 'Child', 'Child, Preschool', 'Follow-Up Studies', 'Humans', 'Hymenoptera', 'Hypersensitivity', 'Immunoglobulin G', 'Immunotherapy', 'Insect Bites and Stings', 'Middle Aged', 'Radioallergosorbent Test', 'Skin Tests'] | 2,600,326 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050'], ['D20.888.065.115', 'D23.946.833.065.115'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B0... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Meningoencephalitis: an atypical presentation of herpes simplex type 2 central nervous system infection. | Encephalitis is the best recognized form of central nervous system (CNS) infection with the herpes simplex virus. We present a case of meningoencephalitis with a benign course caused by herpes simplex virus type 2. The patient had no focal abnormalities on either brain magnetic resonance imaging scan or electroencephal... | ['Diagnosis, Differential', 'Female', 'Herpes Genitalis', 'Herpesvirus 2, Human', 'Humans', 'Immunologic Deficiency Syndromes', 'Meningoencephalitis', 'Middle Aged'] | 9,584,606 | [['E01.171'], ['C01.221.812.640.350', 'C01.778.640.350', 'C01.925.256.466.382.290', 'C01.925.813.350', 'C12.294.329', 'C13.351.500.342'], ['B04.280.382.100.750.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.673'], ['C01.207.245.550', 'C01.207.570', 'C10.228.140.430.550', 'C10.228.228.245.550', 'C10.228.2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Late ureteric obstruction in renal transplantation. | 5 cases of ureteric obstruction occurring in renal allotransplant recipients who had received their grafts more than 3 years prior to presentation are reviewed. | ['Adult', 'Female', 'Humans', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Time Factors', 'Transplantation, Homologous', 'Ureteral Obstruction'] | 322,786 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['M01.060.116.630'], ['G01.910.857'], ['E04.936.864'], ['C12.777.725.776', 'C13.351.968.725.776']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Acceptability of an Opioid Relapse Prevention Text-message Intervention for Emergency Department Patients. | OBJECTIVE: To explore whether a text message-based relapse prevention intervention (Preventing and Interrupting Early Relapse [PIER]1) is acceptable to treatment-seeking adults with opioid use disorder (OUD) after Emergency Department (ED) discharge using mixed-methods design.METHODS: Adults seeking care in an urban ED... | ['Adult', 'Aftercare', 'Emergency Service, Hospital', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Opioid-Related Disorders', 'Outcome and Process Assessment, Health Care', 'Patient Acceptance of Health Care', 'Patient Discharge', 'Secondary Prevention', 'Social Support', 'Text Messaging', 'Young Adult'] | 28,858,888 | [['M01.060.116'], ['E02.760.169.063', 'N02.421.585.169.063', 'N04.590.233.727.210.063'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C25.775.643.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Acaricide resistance in Rhipicephalus microplus collected from selected districts of Madhya Pradesh, Uttar Pradesh and Punjab states of India. | The isolates of Rhipicephalus microplus collected from Madhya Pradesh (MP), Punjab (PJB) and Uttar Pradesh (UP) states of India were characterized using laboratory standardized adult immersion test (AIT) against macrocyclic lactone (ivermectin), synthetic pyrethroids (cypermethrin and deltamethrin), organophosphates (c... | ['Acaricides', 'Animal Distribution', 'Animals', 'India', 'Insecticide Resistance', 'Rhipicephalus'] | 31,463,660 | [['D27.720.031.700.071', 'D27.888.723.071'], ['F01.145.113.069', 'G16.049'], ['B01.050'], ['Z01.252.245.393'], ['G07.690.773.984.491'], ['B01.050.500.131.166.132.832.400.712']] | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Improving the accuracy of a fluid transport method. | AIM: To compare the sealing ability of the same root fillings when measured by a conventional fluid transport method that uses water or by a modified fluid transport method that uses a wetting fluid as tracer.METHODOLOGY: The amount of fluid transport along the same root fillings (AH26, cold lateral compaction of gutta... | ['Analysis of Variance', 'Bismuth', 'Cross-Over Studies', 'Epoxy Resins', 'Gutta-Percha', 'Humans', 'Hydrodynamics', 'Root Canal Filling Materials', 'Root Canal Irrigants', 'Root Canal Obturation', 'Silver', 'Titanium', 'Wettability', 'Wetting Agents'] | 23,013,159 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D01.268.271.245', 'D01.268.556.100', 'D01.496.749.305.245', 'D01.552.544.100'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D05.750.716.822.461', 'D25.720.716.822.461', 'J01.637.051.720.716.822.461'], ['D20.215.721.061', 'D25... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Prolonged remission in a child with chronic myeloid leukemia following Parvo virus B19 (B19V) infection. | Parvovirus B19 (B19V) has been associated with a wide spectrum of clinico-pathological disorders in human beings depending upon the host immunity. The present report describes a child with chronic myeloid leukemia ( CML) on hydroxyurea in haematological remission, who developed profound erythroid suppression following ... | ['Antibodies, Viral', 'Bone Marrow', 'Child', 'Humans', 'Inclusion Bodies, Viral', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Male', 'Microscopy', 'Parvoviridae Infections', 'Parvovirus B19, Human', 'Remission, Spontaneous'] | 26,068,352 | [['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['A15.382.216'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.420.390', 'G06.920.400'], ['C04.557.337.539.250', 'C15.378.190.636.370'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['C01.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Pharmacology of the peptidomimetic, MEN 11149, a new potent, selective and orally effective tachykinin NK1 receptor antagonist. | In this study we investigated the pharmacological properties of MEN 11149, 2-(2-naphthyl)-1-N-[(1R,2S)-2-N-[1(H)indol-3-ylcarbonyl]aminocy clohexanecarbonyl]-1-[N'-methyl-N'-(4-methylphenylacetyl)]di aminoethane, a novel partially retro-inverse pseudo peptide antagonist of tachykinin NK1 receptors. MEN 11149 potently i... | ['Administration, Oral', 'Animals', 'Blood Proteins', 'Bronchoconstriction', 'Guinea Pigs', 'Humans', 'Ileum', 'Indoles', 'Ion Channels', 'Male', 'Muscle Contraction', 'Naphthalenes', 'Receptors, Tachykinin', 'Substance P', 'Tachykinins', 'Tumor Cells, Cultured'] | 9,543,241 | [['E02.319.267.100'], ['B01.050'], ['D12.776.124'], ['G09.772.705.700.080'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684.249', 'A03.556.249.124'], ['D03.633.100.473'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['G11.427.494'], ['D0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of Priming on Patient-Reported Outcome Measures: A Randomized Controlled Trial. | BACKGROUND: Patient-reported outcome measures (PROMs) are influenced by psychosocial factors, but it is unknown whether we can influence PROM scores by modifying the mindset of the patient.PURPOSE: We assessed whether priming affects scores on PROMs.METHODS: In all, 168 patients with musculoskeletal illness participate... | ['Adult', 'Aged', 'Arm Injuries', 'Carpal Tunnel Syndrome', 'Catastrophization', 'Depression', 'Double-Blind Method', 'Female', 'Hand Injuries', 'Humans', 'Male', 'Middle Aged', 'Pain', 'Pain Measurement', 'Patient Reported Outcome Measures', 'Repetition Priming', 'Surveys and Questionnaires', 'Trigger Finger Disorder'... | 26,683,347 | [['M01.060.116'], ['M01.060.116.100'], ['C26.088'], ['C10.668.829.500.500.200', 'C10.668.829.550.200', 'C26.844.150.206'], ['F01.100.575', 'F01.470.132.225'], ['F01.145.126.350'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C26.448'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reading visually embodied meaning from the brain: Visually grounded computational models decode visual-object mental imagery induced by written text. | Embodiment theory predicts that mental imagery of object words recruits neural circuits involved in object perception. The degree of visual imagery present in routine thought and how it is encoded in the brain is largely unknown. We test whether fMRI activity patterns elicited by participants reading objects' names inc... | ['Brain Mapping', 'Cerebral Cortex', 'Concept Formation', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Imagination', 'Magnetic Resonance Imaging', 'Male', 'Models, Theoretical', 'Pattern Recognition, Visual', 'Reading', 'Semantics'] | 26,188,260 | [['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['F02.463.785.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['F02.463.188.634'], ['E01.370.350.825.500'], ['E05.599'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['L01.559.423.557... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Tubeless percutaneous nephrolithotomy for geriatric patients. | AIM: To evaluate the safety of tubeless percutaneous nephrolithotomy (PCNL) in geriatric patients.MATERIALS AND METHOD: This is a retrospective review of 401 patients who received tubeless PCNL in a single institute. Among these, 50 were performed in patients aged older than 70 years (group 1), while 351 were performed... | ['Adult', 'Aged', 'Aged, 80 and over', 'Health Services for the Aged', 'Humans', 'Middle Aged', 'Nephrostomy, Percutaneous', 'Patient Selection', 'Retrospective Studies', 'Risk Assessment', 'Time Factors', 'Treatment Outcome', 'Urolithiasis'] | 19,440,026 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N02.421.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.390.550', 'E04.579.642', 'E04.950.774.739.500', 'E04.950.774.852.642'], ['E05.581.500.653', 'N04.590.731'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.75... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Effects of Nd:YAG laser irradiation on ventricular myocardium in dogs using an artificial sapphire tip contact laser catheter]. | To apply Nd:YAG laser irradiation through a new sapphire tip contact laser method to catheter ablation in treatment of tachy-arrhythmias, effects of laser irradiation on ventricular myocardium were investigated in 10 mongrel dogs. Nd:YAG lase (1064nm) discharges were delivered to different sites on the endomyocardium a... | ['Animals', 'Catheter Ablation', 'Dogs', 'Lasers', 'Myocardium', 'Tachycardia, Ventricular'] | 1,439,268 | [['B01.050'], ['E02.808.750.500', 'E04.014.760.500'], ['B01.050.150.900.649.313.750.250.216.200'], ['E07.632.490', 'E07.710.520'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['C14.280.067.845.940', 'C14.280.123.875.940', 'C23.550.073.845.940']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Cardiopulmonary by-pass with cardiac arrest and deep hypothermia for the surgical treatment of tumor thrombi in the vena cava caused by kidney carcinoma]. | The by-pass technique with controlled cardiac arrest and hypothermia is probably the best method for an extirpation of intracava tumoral thrombi in renal tumours. The technique is easy to perform, represents a great help in the extirpation of thrombi regardless their size and location, and avoids massive bleeding. | ['Adult', 'Aged', 'Cardiopulmonary Bypass', 'Heart Arrest, Induced', 'Humans', 'Hypothermia, Induced', 'Kidney Neoplasms', 'Middle Aged', 'Neoplasm Invasiveness', 'Thrombosis', 'Venae Cavae'] | 2,288,250 | [['M01.060.116'], ['M01.060.116.100'], ['E04.292.413'], ['E04.100.376.374', 'E04.928.220.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.258.750'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['M01.060.116.630'], ['C04.697.645', 'C23.550.727... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Requirement for neo1p in retrograde transport from the Golgi complex to the endoplasmic reticulum. | Neo1p from Saccharomyces cerevisiae is an essential P-type ATPase and potential aminophospholipid translocase (flippase) in the Drs2p family. We have previously implicated Drs2p in protein transport steps in the late secretory pathway requiring ADP-ribosylation factor (ARF) and clathrin. Here, we present evidence that ... | ['Adenosine Triphosphatases', 'Amino Acid Sequence', 'COP-Coated Vesicles', 'Cell Membrane Structures', 'Cloning, Molecular', 'Endoplasmic Reticulum', 'Glycosylation', 'Golgi Apparatus', 'Membrane Proteins', 'Membrane Transport Proteins', 'Microscopy, Electron', 'Models, Molecular', 'Molecular Sequence Data', 'Phosphol... | 12,960,419 | [['D08.811.277.040.025'], ['G02.111.570.060', 'L01.453.245.667.060'], ['A11.284.430.214.190.875.190.880.180.180'], ['A11.284.149.165'], ['E05.393.220'], ['A11.284.430.214.190.875.248'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['A11.284.430.214.190.875.336'], ['D12.776.543'], ['D12.776.157.530', 'D12.776.543.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Enhanced expression of Gqá and PLC-â1 proteins contributes to vascular smooth muscle cell hypertrophy in SHR: role of endogenous angiotensin II and endothelin-1. | Vascular Gqá signaling has been shown to contribute to cardiac hypertrophy. In addition, angiotensin II (ANG II) was shown to induce vascular smooth muscle cell (VSMC) hypertrophy through Gqá signaling; however, the studies on the role of Gqá and PLC-â1 proteins in VSMC hypertrophy in animal model are lacking. The pres... | ['Angiotensin II', 'Animals', 'Cells, Cultured', 'Disease Models, Animal', 'Endothelin-1', 'Extracellular Signal-Regulated MAP Kinases', 'GTP-Binding Protein alpha Subunits, Gq-G11', 'Hypertension', 'Hypertrophy', 'Male', 'Muscle, Smooth, Vascular', 'Myocytes, Smooth Muscle', 'NF-kappa B', 'Phospholipase C beta', 'Phos... | 24,760,983 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['A11.251'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.644.276.400.225', 'D12.776.467.400.225', 'D23.529.400.225'], ['D08.811.913.696.620.682.700.567.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tetrahymena eukaryotic translation elongation factor 1A (eEF1A) bundles filamentous actin through dimer formation. | Eukaryotic translation elongation factor 1A (eEF1A) is known to be a multifunctional protein. In Tetrahymena, eEF1A is localized to the division furrow and has the character to bundle filamentous actin (F-actin). eEF1A binds F-actin and the ratio of eEF1A and actin is approximately 1:1 (Kurasawa et al., 1996). In this ... | ['Actins', 'Animals', 'Calmodulin', 'Chromatography, Gel', 'Dimerization', 'Electrophoresis, Polyacrylamide Gel', 'Immunoblotting', 'Microscopy, Electron', 'Peptide Elongation Factor 1', 'Tetrahymena'] | 16,877,446 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['E05.196.181.400.250'], ['G02.206', 'G03.230'], ['E05.196.401.402', 'E05.301.300.319'], ['E05.478.566.320', 'E05.601.470.320'], ['E01.370.350.515.402', 'E05.59... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Complete Genome of Bacillus velezensis CMT-6 and Comparative Genome Analysis Reveals Lipopeptide Diversity. | The complete genome sequence of Bacillus velezensis type strain CMT-6 is presented for the first time. A comparative analysis between the genome sequences of CMT-6 with the genome of Bacillus amyloliquefaciens DSM7T, B. velezensis FZB42, and Bacillus subtilis 168 revealed major differences in the lipopeptide synthesis ... | ['Bacillus', 'Bacterial Proteins', 'Genetic Variation', 'Genome, Bacterial', 'Lipopeptides', 'Peptide Synthases', 'Whole Genome Sequencing'] | 31,098,827 | [['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['D12.776.097'], ['G05.365'], ['G05.360.340.358.207'], ['D10.477', 'D12.644.365'], ['D08.811.464.259.850'], ['E05.393.760.700.825']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transcatheter renal artery embolization in the treatment of infected cutaneous ureterostomy. | Palliative renal ablation by means of transcatheter embolization is described. A patient with left cutaneous ureterostomy suffered from urosepsis. The left kidney was embolized using isobutyl-2-cyanoacrylate and Lipiodol in order to stop infected urine excretion. Complete recovery was achieved. | ['Dermatologic Surgical Procedures', 'Embolization, Therapeutic', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Pseudomonas Infections', 'Renal Artery', 'Urinary Diversion'] | 4,019,094 | [['E04.680.275'], ['E02.520.360', 'E02.926.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['C01.150.252.400.739'], ['A07.015.114.745'], ['E04.950.774.852']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Validity and reliability of the ten-item Connor-Davidson Resilience Scale (CD-RISC10) instrument in patients with axial spondyloarthritis (axSpA) in Singapore. | We aimed to assess the validity and reliability of the ten-item Connor-Davidson Resilience Scale (CD-RISC10) in patients with axial spondyloarthritis (axSpA) in Singapore. We used cross-sectional data from 108 patients with axSpA recruited from a dedicated axSpA clinic in a Singapore tertiary referral hospital from 201... | ['Adult', 'Aged', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Psychometrics', 'Reproducibility of Results', 'Resilience, Psychological', 'Singapore', 'Spondylarthritis', 'Surveys and Questionnaires', 'Translations'] | 30,523,476 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['F02.940'], ['Z01.252.145.774'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
In vivo effect of copper status on cisplatin-induced nephrotoxicity. | Cisplatin is a widely used antitumor agent; however, tumor resistance and severe side effects limit its use. It is well accepted that cisplatin toxicity can be modulated in vitro in cell cultures by copper salts. In the present work, mice with different blood serum copper status were treated with a single intraperitone... | ['Animals', 'Antineoplastic Agents', 'Cisplatin', 'Copper Sulfate', 'Injections, Intraperitoneal', 'Kidney', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Platinum', 'Proteinuria', 'Tissue Distribution'] | 27,481,100 | [['B01.050'], ['D27.505.954.248'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D01.875.800.800.850.150'], ['E02.319.267.530.490'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D01.268.556.690', 'D01.268.956.734',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of extracellular bicarbonate on the short-circuit current and intracellular free calcium of human cultured sweat duct cells. | Transepithelial short-circuit current (Iscc) and intracellular free Ca2+ (Ca2+i) was studied in monolayers of cultured human sweat duct cells (CSDCs) in the presence or absence of HCO3- (and CO2) in the bathing solutions. Addition of HCO3- (and CO2) increased the control Iscc by more than 50%. The effect of HCO3- (and ... | ['Amiloride', 'Bicarbonates', 'Buffers', 'Calcium', 'Cells, Cultured', 'Electrophysiology', 'Extracellular Space', 'Humans', 'Intracellular Membranes', 'Methacholine Chloride', 'Sweat Glands'] | 1,489,544 | [['D03.383.679.149'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['D27.720.470.280'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251'], ['H01.158.344.528', 'H01.158.782.236'], ['A10.082.500', 'A11.284.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.149.450', 'A11.284.835.514... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Selective Separation of Isomeric Dicarboxylic Acid by the Preferable Crystallization of Metal-Organic Frameworks. | Simple and effective separation of isomeric organic molecules is an important but challenging task. Herein, we successfully developed a selective crystallization strategy to separate the mixtures of isomeric dicarboxylic acids (DCAs) for the first time. The target DCAs could be preferably combined with crystallization ... | ['Crystallization', 'Dicarboxylic Acids', 'Metal-Organic Frameworks', 'Molecular Structure', 'Powder Diffraction', 'Zirconium'] | 30,444,305 | [['E05.196.300', 'G02.171'], ['D02.241.081.337'], ['D02.691.638', 'D05.750.215'], ['G02.111.570', 'G02.466'], ['E05.196.309.711'], ['D01.268.556.950', 'D01.268.956.937', 'D01.552.544.950']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stable Regulation of Senescence-Related Genes in Galactose-alpha1,3-galactose Epitope Knockout and Human Membrane Cofactor Protein hCD46 Pig. | BACKGROUND: Pigs are considered suitable animal donor models for xenotransplantation. For successful organ transplantation, immune rejection must be overcome. Xenotransplantation has recently been successfully performed using galactose-alpha1,3-galactose epitopes knockout (GalTKO) and a human membrane cofactor protein ... | ['Aging', 'Animals', 'Animals, Genetically Modified', 'Child, Preschool', 'Disease Models, Animal', 'Epitopes', 'Galactose', 'Galactosyltransferases', 'Gene Knockout Techniques', 'Graft Survival', 'Heterografts', 'Humans', 'Membrane Cofactor Protein', 'Middle Aged', 'Swine', 'Swine, Miniature', 'Transplantation, Hetero... | 31,399,182 | [['G07.345.124'], ['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['M01.060.406.448'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D23.050.550'], ['D09.947.875.359.377'], ['D08.811.913.400.450.400'], ['E05.393.335.750'], ['G12.875.545.340'], ['A01.941.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bioaccessibility of barium from barite contaminated soils based on gastric phase in vitro data and plant uptake. | Barite contamination of soil commonly occurs from either barite mining or explorative drilling operations. This work reported in vitro data for barite contaminated soils using the physiologically based extraction test (PBET) methodology. The existence of barite in plant tissue and the possibility of 'biomineralised' zo... | ['Barium', 'Barium Sulfate', 'Biological Availability', 'Child', 'Child, Preschool', 'Humans', 'Risk Assessment', 'Soil Pollutants', 'South Australia', 'Spinacia oleracea', 'Stomach'] | 26,495,826 | [['D01.268.552.050', 'D01.268.556.062', 'D01.552.539.124', 'D01.552.544.062'], ['D01.103.075', 'D01.875.800.800.850.075'], ['G03.787.151', 'G07.690.725.129'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.69... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hybrid cysts: a clinicopathological study of seven cases. | Hybrid cysts develop from more than two components of the pilosebaceous unit. The pathogenesis of this unusual disease has not yet been elucidated. The aim of this study was to assess the clinical and histopathological features of hybrid cysts. Histological sections of seven cases indexed as hybrid cysts were reviewed ... | ['Adolescent', 'Adult', 'Child', 'Epidermal Cyst', 'Female', 'Hair Diseases', 'Humans', 'Male', 'Middle Aged', 'Pilomatrixoma', 'Retrospective Studies', 'Skin Neoplasms'] | 22,309,332 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['C04.182.254'], ['C17.800.329'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.470.565.625'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.5... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Isomalt production by cloning, purifying and expressing of the MDH gene from Pseudomonas fluorescens DSM 50106 in different strains of E. coli. | A NADH-dependent mannitol dehydrogenase gene (mtlD) was cloned from Pseudomonas fluorescens, subcloned into an expression vector (pDEST110) and entered into different strains of E. coli to compare their protein expression and the enzyme specific activity. Purifications were accomplished by Ni(2+)-NTA affinity chromatog... | ['Base Sequence', 'Chromatography, High Pressure Liquid', 'Chromatography, Thin Layer', 'Cloning, Molecular', 'Escherichia coli', 'Gene Expression', 'Genetic Vectors', 'Isoenzymes', 'Mannitol Dehydrogenases', 'Models, Molecular', 'Molecular Sequence Data', 'NAD', 'Protein Structure, Tertiary', 'Pseudomonas fluorescens'... | 19,266,906 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.181.400.300'], ['E05.196.181.400.537'], ['E05.393.220'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.297'], ['G05.360.337'], ['D08.811.348', 'D12.776.800.300'], ['D08.811.682.047.150.700.649'], ['E05.599.595'], ['L01.453.245.667'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Out-of-pocket healthcare expenditure and chronic disease - do Australians forgo care because of the cost? | Although we do know that out-of-pocket healthcare expenditure is relatively high in Australia, little is known about what health conditions are associated with the highest out-of-pocket expenditure, and whether the cost of healthcare acts as a barrier to care for people with different chronic conditions. Cross-sectiona... | ['Adult', 'Aged', 'Asthma', 'Australia', 'Chronic Disease', 'Cross-Sectional Studies', 'Female', 'Financing, Personal', 'Health Expenditures', 'Humans', 'Male', 'Middle Aged', 'Pulmonary Disease, Chronic Obstructive', 'Pulmonary Emphysema', 'Risk Factors'] | 28,442,033 | [['M01.060.116'], ['M01.060.116.100'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['Z01.639.100', 'Z01.678.100.373'], ['C23.550.291.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N03.219.559'], ['N03.219.151.450', 'N05.300.385'], ['B01.050.150.900.... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Repeatability of Brain Volume Measurements Made with the Atlas-based Method from T1 | PURPOSE: An understanding of the repeatability of measured results is important for both the atlas-based and voxel-based morphometry (VBM) methods of magnetic resonance (MR) brain volumetry. However, many recent studies that have investigated the repeatability of brain volume measurements have been performed using stat... | ['Adult', 'Anatomy, Artistic', 'Atlases as Topic', 'Brain', 'Cerebellum', 'Cerebrospinal Fluid', 'Female', 'Gray Matter', 'Hippocampus', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Organ Size', 'Prefrontal Cortex', 'White Matter', ... | 26,841,856 | [['M01.060.116'], ['H01.158.100.091', 'K01.093.410.100'], ['L01.178.682.192.836.147'], ['A08.186.211'], ['A08.186.211.132.810.428.200'], ['A12.207.270.210'], ['A08.186.211.168', 'A08.186.854.348'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Humanities [K]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
Infectious diseases in competitive sports. | OBJECTIVE: Participation in competitive sports is popular and widely encouraged throughout the United States. Reports of infectious disease outbreaks among competitive athletes and recent publicity regarding infectious disease concerns in sports underscore the need to better characterize the occurrence of these problem... | ['Communicable Disease Control', 'Communicable Diseases', 'Data Collection', 'Disease Outbreaks', 'HIV Infections', 'Humans', 'Information Systems', 'MEDLINE', 'Newspapers as Topic', 'Sports', 'United States'] | 8,114,242 | [['N06.850.780.200'], ['C01.221', 'C23.550.291.531'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N06.850.290'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.... | ['Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Providing a genitourinary medicine colposcopy service. | Between 15 and 30 years ago, the management of women with abnormal cervical cytology fell within the remit of GU Medicine. This involved performing colposcopy. With the introduction of certification for colposcopists in 1998, most GU Medicine clinicians stopped providing a colposcopy service. As certification is not re... | ['Adolescent', 'Adult', 'Cervix Uteri', 'Colposcopy', 'Female', 'Female Urogenital Diseases', 'Humans', 'Metrorrhagia', 'Middle Aged', 'Practice Guidelines as Topic', 'Referral and Consultation', 'United Kingdom'] | 23,893,915 | [['M01.060.057'], ['M01.060.116'], ['A05.360.319.679.256'], ['E01.370.378.150', 'E01.370.388.250.150', 'E04.502.250.150', 'E04.520.150', 'E04.950.300.210'], ['C13.351'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.852.691.622', 'C23.550.414.993.700'], ['M01.060.116.630'], ['N04.761.700.350.650', 'N05... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Double branched flicker fusion curves from the all-rod skate retina. | Electrical responses from the skate retina will only follow flicker up to frequencies of 5 hertz when intensities are below rod saturation. At greater luminances, the eye responds to rates as high as 30 hertz. As a result, a plot of critical flicker fusion as a function of intensity is a double branched curve. It seems... | ['Animals', 'Aspartic Acid', 'Fishes', 'Flicker Fusion', 'Membrane Potentials', 'Photoreceptor Cells'] | 1,215,989 | [['B01.050'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['B01.050.150.900.493'], ['E01.370.380.245', 'F02.463.593.932.458', 'G14.370'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['A08.675.650.850.625', 'A08.675.650.915.937', 'A08.800.950.937', 'A09.371.729.831.625', 'A11.671.650.850.625... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Surgical evaluation of a liver transplant program. Experiences with the first 45 cases]. | The cumulative experience in liver transplantation since the introduction of cyclosporine A has confirmed its efficacy in the treatment of diverse liver diseases in children and adults. In the present study we review the surgical aspects of 45 transplants performed in 39 patients (17 children and 22 adults). Immunosupp... | ['Adolescent', 'Adult', 'Anastomosis, Surgical', 'Child', 'Child, Preschool', 'Choledochostomy', 'Evaluation Studies as Topic', 'Female', 'Hepatectomy', 'Hepatic Artery', 'Hepatic Veins', 'Humans', 'Infant', 'Liver Transplantation', 'Male', 'Middle Aged', 'Portal Vein'] | 2,672,181 | [['M01.060.057'], ['M01.060.116'], ['E04.035'], ['M01.060.406'], ['M01.060.406.448'], ['E04.035.200', 'E04.210.120.200'], ['E05.337', 'N05.715.360.335'], ['E04.210.556'], ['A07.015.114.407'], ['A07.015.908.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.095.147.725.490', 'E04.210.650', 'E... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Percutaneous fenestration of dissecting intima with a transseptal needle. A new therapeutic technique for visceral ischemia complicating acute aortic dissection. | Noncardiac visceral ischemia is a major complication with acute aortic dissection and is caused by obstruction of the major visceral arteries by dissecting intima. Two patients with this condition underwent emergency percutaneous fenestration of dissecting intima, and the blood flow to the lower extremity and kidney wa... | ['Aneurysm, Dissecting', 'Angioplasty, Balloon', 'Aorta, Abdominal', 'Aorta, Thoracic', 'Aortic Aneurysm', 'Aortography', 'Catheters, Indwelling', 'Emergencies', 'Female', 'Humans', 'Ischemia', 'Kidney', 'Leg', 'Male', 'Middle Aged', 'Needles', 'Postoperative Complications'] | 1,535,024 | [['C14.907.055.050'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['A07.015.114.056.205'], ['A07.015.114.056.372'], ['C14.907.055.239', 'C14.907.109.139'], ['E01.370.350.700.060.070', 'E01.370.370.050.070'], ['E07.132.500'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.3... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Age and hearing loss and the use of acoustic cues in fricative categorization. | This study examined the use of fricative noise information and coarticulatory cues for categorization of word-final fricatives [s] and [f] by younger and older Dutch listeners alike. Particularly, the effect of information loss in the higher frequencies on the use of these two cues for fricative categorization was inve... | ['Acoustic Stimulation', 'Age Factors', 'Aged', 'Cues', 'Female', 'Hearing Loss', 'Humans', 'Male', 'Models, Biological', 'Netherlands', 'Phonetics', 'Sound Spectrography', 'Speech', 'Young Adult'] | 26,428,779 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['F02.463.425.234'], ['C09.218.458.341', 'C10.597.751.418.341', 'C23.888.592.763.393.341'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['Z01.542.651'], ['L01.559.598.518'], ['E05.855'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
DNA damage induced by seven N-nitroso compounds in primary cultures of human and rat kidney cells. | Seven N-nitroso compounds (NOC), known to induce kidney tumors in rats, were assayed for DNA-damaging activity in primary cultures of human and rat kidney cells. DNA fragmentation was measured by the alkaline elution technique. Positive responses were obtained in cells of both species with N-nitrosodimethylamine (32 mM... | ['Animals', 'Biotransformation', 'Carcinogens', 'Cells, Cultured', 'DNA Damage', 'Humans', 'Kidney', 'Male', 'Nitroso Compounds', 'Rats', 'Rats, Sprague-Dawley'] | 8,637,509 | [['B01.050'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['D27.888.569.100'], ['A11.251'], ['G05.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['D02.654'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of various carbon sources on cholinesterase formation by Arthrobacter simplex var. cholinesterasus]. | The effect of carbohydrates, aromatic alcohols, choline and acetylcholine on the biomass production and biosynthesis of choline esterase was studied with Arthrobacter simplex var. cholinesterasus. Fructose was found to be the best carbon source for the biomass accumulation and synthesis of choline esterase. Almost the ... | ['Acetylcholine', 'Alcohols', 'Arthrobacter', 'Carbon', 'Choline', 'Cholinesterases', 'Enzyme Induction', 'Fructose', 'Glucose', 'Maltose'] | 1,004,262 | [['D02.092.211.111'], ['D02.033'], ['B03.510.024.850.050', 'B03.510.460.400.400.049.074'], ['D01.268.150'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['D08.811.277.352.100.170'], ['G05.308.320.200'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['D09.947.875.359.448'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Behavioral thermoregulation of the toad, Bufo marinus: effects of air humidity. | Two experiments were performed. The first tested the hypothesis that the toad, Bufo marinus, will select a lower ambient temperature under dry environmental conditions. This behavioral response would reduce evaporative water loss and facilitate survival on land. The second experiment measured the effects of temperature... | ['Animals', 'Behavior, Animal', 'Body Temperature Regulation', 'Body Water', 'Bufo marinus', 'Data Interpretation, Statistical', 'Environment', 'Temperature'] | 1,909,745 | [['B01.050'], ['F01.145.113'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['A12.207.200'], ['B01.050.150.900.090.180.210.580'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['G16.500.275', 'N06.230'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Evaluation of the Bladder Stimulation Technique to Collect Midstream Urine in Infants in a Pediatric Emergency Department. | OBJECTIVE: Midstream clean-catch urine is an accepted method to diagnose urinary tract infection but is impracticable in infants before potty training. We tested the bladder stimulation technique to obtain a clean-catch urine sample in infants.MATERIALS AND METHODS: We included 142 infants under walking age who require... | ['Cross-Sectional Studies', 'Emergency Service, Hospital', 'Female', 'France', 'Hospitals, Pediatric', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Odds Ratio', 'Risk Factors', 'Urinary Bladder', 'Urinary Tract Infections', 'Urine Specimen Collection'] | 27,031,953 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['Z01.542.286'], ['N02.278.421.556.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.740.600.600', 'G17.680.500... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Perceived suprathreshold depth under conditions that elevate the stereothreshold. | PURPOSE: Previous studies considered the possibility that individuals with impaired stereoacuity can be identified by estimating the perceived depth of a target with a suprathreshold retinal image disparity. These studies showed that perceived suprathreshold depth is reduced when the image presented to one eye is blurr... | ['Adult', 'Depth Perception', 'Female', 'Humans', 'Male', 'Middle Aged', 'Sensory Thresholds', 'Vision Disparity', 'Vision, Binocular', 'Visual Acuity', 'Young Adult'] | 23,160,439 | [['M01.060.116'], ['F02.463.593.200', 'F02.463.593.778.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.463.593.710'], ['F02.463.593.778.255.780', 'F02.463.593.932.877', 'G14.930'], ['F02.463.593.932.885'], ['E01.370.380.850.950', 'F02.463.593.932.901', 'G14.940'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multiple interactions among the components of the recombinational DNA repair system in Schizosaccharomyces pombe. | Schizosaccharomyces pombe Rhp55 and Rhp57 are RecA-like proteins involved in double-strand break (DSB) repair. Here we demonstrate that Rhp55 and Rhp57 proteins strongly interact in vivo, similar to Saccharomyces cerevisiae Rad55p and Rad57p. Mutations in the conserved ATP-binding/hydrolysis folds of both the Rhp55 and... | ['Adenosine Triphosphatases', 'Adenosine Triphosphate', 'Alleles', 'Animals', 'Chromosomes', 'DNA', 'DNA Helicases', 'DNA Repair', 'DNA-Binding Proteins', 'Dimerization', 'Evolution, Molecular', 'Fungal Proteins', 'Gene Deletion', 'Hydrolysis', 'Methyl Methanesulfonate', 'Mice', 'Models, Biological', 'Mutagens', 'Mutat... | 11,560,889 | [['D08.811.277.040.025'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G05.360.340.024.340.030'], ['B01.050'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['D13.444.308'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['G02.111.222', 'G05.219'], ['D12.776.260'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gene mapping in Alport families with different basement membrane antigenic phenotypes. | The present study was undertaken to determine whether differences among Alport kindreds in the antigenic phenotypes of their basement membranes result from defects at distinct genetic loci or from allelic mutations at a single locus. We analyzed linkage of the Alport gene to polymorphic loci on the X chromosome in thre... | ['Antibodies', 'Antigens', 'Autoantibodies', 'Basement Membrane', 'Chromosome Mapping', 'Collagen', 'Female', 'Genetic Linkage', 'Humans', 'Kidney Glomerulus', 'Male', 'Nephritis, Hereditary', 'Phenotype', 'X Chromosome'] | 2,266,677 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D23.050'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['A10.272.220', 'A10.615.179'], ['E05.393.183'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G05.348'], ['B01.050.150.900.649.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A case report: ulcerative colitis, treatment with an antibody against tumor necrosis factor (infliximab), and subsequent liver necrosis. | In recent years, the use of antibodies against tumor necrosis factor á (TNFá) has expanded in rheumatology, gastroenterology, and dermatology. In addition to the more common side effects such as infections and hypersensitivity reactions, elevations of liver enzymes have been reported during anti-TNFá therapy, although ... | ['Anti-Inflammatory Agents', 'Antibodies, Monoclonal', 'Chemical and Drug Induced Liver Injury', 'Colitis, Ulcerative', 'Female', 'Humans', 'Infliximab', 'Liver Failure, Acute', 'Middle Aged', 'Necrosis'] | 22,398,069 | [['D27.505.954.158'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
T-cell prolymphocytic leukemia: an aggressive T cell malignancy with frequent cutaneous tropism. | BACKGROUND: T-cell prolymphocytic leukemia (T-PLL), formerly categorized as T-cell chronic lymphocytic leukemia, is a rare and aggressive hematologic malignancy. Although the skin is characteristically involved, it is not a well-recognized entity in the dermatologic literature.METHODS: Six cases of cutaneous T-PLL are ... | ['Aged', 'Aged, 80 and over', 'Aneuploidy', 'Antigens, CD', 'Antigens, Neoplasm', 'CD4-Positive T-Lymphocytes', 'CD52 Antigen', 'CD8-Positive T-Lymphocytes', 'Cytogenetic Analysis', 'Face', 'Female', 'Gene Amplification', 'Gene Rearrangement', 'Glycoproteins', 'Humans', 'In Situ Hybridization, Fluorescence', 'Leukemia,... | 16,908,353 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.285'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['D12.776.395.550.448.190', 'D12.776.543.484.500.190',... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neuroplasticity in dynamic neural networks comprised of neurons attached to adaptive base plate. | In this paper, a learning algorithm is developed for Dynamic Plastic Continuous Neural Networks (DPCNNs) to improve their learning of highly nonlinear time dependent problems. A DPCNN is comprised of a base medium, which is nonlinear and plastic, and a number of neurons that are attached to the base by wire-like connec... | ['Adaptation, Physiological', 'Algorithms', 'Brain', 'Computer Simulation', 'Humans', 'Neural Networks, Computer', 'Neuronal Plasticity', 'Neurons', 'Nonlinear Dynamics'] | 26,722,981 | [['G07.025', 'G16.012.500'], ['G17.035', 'L01.224.050'], ['A08.186.211'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17.485', 'L01.224.050.375.605'], ['G11.561.638'], ['A08.675', 'A11.671'], ['E05.599.850', 'H01.548.675']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Cerebellar soluble lectin and its glycoprotein ligands in the developing brain of control and dysmyelinating mutant mice. | The levels of an endogenous lectin, the cerebellar soluble lectin (CSL) and of its endogenous glycoprotein ligands were studied using immunoblotting and affinoblotting techniques in the forebrain of quaking, shiverer and jimpy dysmyelinating mutant mice and their respective control littermates during the postnatal deve... | ['Aging', 'Alkaline Phosphatase', 'Animals', 'Avidin', 'Biotin', 'Brain', 'Demyelinating Diseases', 'Glycoproteins', 'Immunoblotting', 'Lectins', 'Mice', 'Mice, Neurologic Mutants', 'Molecular Weight'] | 8,439,766 | [['G07.345.124'], ['D08.811.277.352.650.035'], ['B01.050'], ['D12.776.034.614.300', 'D12.776.256.159.157.663.300', 'D12.776.290.663.100', 'D12.776.395.175'], ['D03.383.129.308.080', 'D08.211.096'], ['A08.186.211'], ['C10.314'], ['D09.400.430', 'D12.776.395'], ['E05.478.566.320', 'E05.601.470.320'], ['D12.776.503'], ['B... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The dual control of TFIIB recruitment by NC2 is gene specific. | Negative co-factor 2 (NC2) is a conserved eukaryotic complex composed of two subunits, NC2alpha (Drap1) and NC2beta (Dr1) that associate through a histone-fold motif. In this work, we generated mutants of NC2, characterized target genes for these mutants and studied the assembly of NC2 and general transcription factors... | ['Dimerization', 'Gene Expression Regulation', 'Heat-Shock Proteins', 'Heat-Shock Response', 'Mutation', 'Oligonucleotide Array Sequence Analysis', 'Phosphoproteins', 'Promoter Regions, Genetic', 'Protein Structure, Tertiary', 'Protein Subunits', 'RNA, Messenger', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae P... | 18,048,413 | [['G02.206', 'G03.230'], ['G05.308'], ['D12.776.580.216'], ['G07.775.500'], ['G05.365.590'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['D12.776.744'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['G02.111.570.820.709.610'], ['D12.776.813'], ['D... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Combined immunohistochemistry for gonadotropin-releasing hormone (GnRH) and pro-GnRH, and in situ hybridization for GnRH messenger ribonucleic acid in rat brain. | Experiments were performed to explore the distribution of neurons containing pro-GnRH and GnRH in the rat brain and to determine the correspondence of immunoreactive peptides and pro-GnRH mRNA. Using avidin-biotin immunohistochemistry on free floating vibratome sections it was found that pro-GnRH- and GnRH-containing c... | ['Animals', 'Brain Chemistry', 'Female', 'Immunohistochemistry', 'Male', 'Neurons', 'Nucleic Acid Hybridization', 'Pituitary Hormone-Releasing Hormones', 'Protein Precursors', 'RNA, Messenger', 'Rats', 'Rats, Inbred Strains'] | 2,651,908 | [['B01.050'], ['G02.111.150', 'G03.185'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['A08.675', 'A11.671'], ['E05.393.661', 'G... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Parkin Protects against Oxygen-Glucose Deprivation/Reperfusion Insult by Promoting Drp1 Degradation. | Ischemic stroke results in severe brain damage and remains one of the leading causes of death and disability worldwide. Effective neuroprotective therapies are needed to reduce brain damage resulting from ischemic stroke. Mitochondria are crucial for cellular energy production and homeostasis. Modulation of mitochondri... | ['Animals', 'Apoptosis', 'Cell Hypoxia', 'Cell Line, Tumor', 'Dynamins', 'Gene Expression Regulation', 'Glucose', 'Mice', 'Mitochondria', 'Neurons', 'Oxygen', 'Proteasome Endopeptidase Complex', 'Proteolysis', 'RNA Interference', 'Reperfusion Injury', 'Signal Transduction', 'Transfection', 'Ubiquitin-Protein Ligases', ... | 27,597,885 | [['B01.050'], ['G04.146.954.035'], ['G03.197.300', 'G04.270.300'], ['A11.251.210.190', 'A11.251.860.180'], ['D08.811.277.040.330.200', 'D12.776.220.600.450.200', 'D12.776.543.990.400'], ['G05.308'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Complete factor I deficiency due to dysfunctional factor I with recurrent aseptic meningo-encephalitis. | PURPOSE: Complement regulators control the activated complement system. Defects in this homeostasis can result in tissue damage and autoimmune diseases with a heterogeneity in clinical presentation. Complement factor I (FI), a serine protease, is an important regulator of alternative pathway activation. We report a dia... | ['Complement Activation', 'Complement Factor I', 'Hemolysis', 'Humans', 'Meningitis, Aseptic', 'Meningoencephalitis', 'Recurrence', 'Sequence Analysis, DNA'] | 24,142,231 | [['G12.274'], ['D08.811.277.656.300.760.210', 'D08.811.277.656.959.350.210', 'D12.776.124.486.274.920.325.210'], ['C23.550.403', 'G12.122.545'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.614.220'], ['C01.207.245.550', 'C01.207.570', 'C10.228.140.430.550', 'C10.228.228.245.550', 'C10.228.228.570', 'C10.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hippocampal adult neurogenesis is enhanced by chronic eszopiclone treatment in rats. | The adult hippocampal dentate gyrus (DG) exhibits cell proliferation and neurogenesis throughout life. We examined the effects of daily administration of eszopiclone (Esz), a commonly used hypnotic drug and gamma-aminobutyric acid (GABA) agonist, compared with vehicle, on DG cell proliferation and neurogenesis, and on ... | ['Animals', 'Azabicyclo Compounds', 'Cell Count', 'Cell Survival', 'Eszopiclone', 'Hippocampus', 'Hypnotics and Sedatives', 'Male', 'Neurogenesis', 'Piperazines', 'Rats', 'Rats, Sprague-Dawley', 'Sleep', 'Time Factors'] | 20,408,925 | [['B01.050'], ['D02.145.074', 'D03.605.084.500'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.346'], ['D03.383.606.398', 'D03.383.679.600', 'D03.383.725.322'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D27.505.696.277.350', 'D27.505.954.427.210.350'], ['G04.152.912', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunolocalization of the PmSUC1 sucrose transporter in Plantago major flowers and reporter-gene analyses of the PmSUC1 promoter suggest a role in sucrose release from the inner integument. | This paper presents a detailed analysis of the PmSUC1 gene from plantago major, of its promoter activity in Arabidopsis, and of the tissue specific localization of the encoded protein in Plantago. PmSUC1 promoter activity was detected in the innermost layer of the inner integument (the endothel) of Arabidopsis plants e... | ['Arabidopsis', 'Blotting, Western', 'Exons', 'Flowers', 'Green Fluorescent Proteins', 'Immunohistochemistry', 'Introns', 'Membrane Transport Proteins', 'Microscopy, Confocal', 'Microscopy, Fluorescence', 'Plant Proteins', 'Plantago', 'Plants, Genetically Modified', 'Pollen', 'Pollen Tube', 'Promoter Regions, Genetic',... | 17,236,100 | [['B01.650.940.800.575.912.250.157.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G05.360.340.024.340.137.232'], ['A18.024.249.500'], ['D12.776.532.265'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', '... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Enumeration and characterization of DJH structures in mouse fetal liver. | The primary immunoglobulin (Ig) repertoire in the mouse develops during fetal life in the liver. The first Ig gene rearrangement--the joining of a DH to a JH gene segment--contributes largely to the diversity found in CDR3, as well as potentially encoding the D mu protein which is believed to function in the developmen... | ['Animals', 'Base Sequence', 'Blotting, Southern', 'Cloning, Molecular', 'DNA', 'Gene Rearrangement', 'Genes, Immunoglobulin', 'Liver', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Molecular Sequence Data', 'Polymerase Chain Reaction'] | 1,582,417 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['E05.393.220'], ['D13.444.308'], ['G05.344'], ['G05.360.340.024.340.335', 'G12.500.299'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.15... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Routine use of ultraviolet light in medicolegal examinations to evaluate stains and skin trauma. | The use of ultraviolet light induced fluorescence as an aid in forensic medical examinations of rape victims was evaluated preliminarily in a retrospective, non-consecutive study. In a four-month period, 17 cases were referred by the police for examinations at the Institute of Forensic Pathology. Ultraviolet light illu... | ['Aged', 'Child', 'Denmark', 'Female', 'Forensic Medicine', 'Humans', 'Male', 'Physical Examination', 'Rape', 'Saliva', 'Semen', 'Ultraviolet Rays'] | 7,776,867 | [['M01.060.116.100'], ['M01.060.406'], ['Z01.542.816.124'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.600'], ['I01.198.240.748.640', 'I01.198.240.856.744', 'I01.880.735.900.772'], ['A12.200.666'], ['A12.200.732'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.7... | ['Named Groups [M]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
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