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Clozapine effects on positive and negative symptoms: a six-month trial in treatment-refractory schizophrenics.
Fifteen DSM-III-R diagnosed schizophrenics characterized by long-term neuroleptic nonresponse and significant negative symptoms were evaluated with the Positive and Negative Syndrome Scale, a well-operationalized measure of psychopathology, on a baseline neuroleptic and weekly thereafter across 26 weeks of clozapine tr...
['Adult', 'Clozapine', 'Female', 'Humans', 'Male', 'Psychological Tests', 'Schizophrenia', 'Time Factors', 'Treatment Failure']
8,027,417
[['M01.060.116'], ['D03.633.300.240.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711'], ['F03.700.750'], ['G01.910.857'], ['E01.789.800.760', 'N04.761.559.590.800.760', 'N05.715.360.575.575.800.760']]
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
0
1
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Capsid proteins from field strains of foot-and-mouth disease virus confer a pathogenic phenotype in cattle on an attenuated, cell-culture-adapted virus.
Chimeric foot-and-mouth disease viruses (FMDVs) have been generated from plasmids containing full-length FMDV cDNAs and characterized. The parental virus cDNA was derived from the cell-culture-adapted O1Kaufbeuren B64 (O1K B64) strain. Chimeric viruses, containing capsid coding sequences derived from the O/UKG/34/2001 ...
['Animals', 'Capsid Proteins', 'Cattle', 'Cattle Diseases', 'Cell Culture Techniques', 'Cells, Cultured', 'Cricetinae', 'Foot-and-Mouth Disease Virus', 'Phenotype', 'Recombinant Proteins', 'Virulence Factors']
21,270,284
[['B01.050'], ['D12.776.964.970.600.550'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.251'], ['B01.050.150.900.649.313.992.635.075.250'], ['B04.820.578.750.070.250'], ['G05.695'], ['D12.776.828'], ['D23.946.896']]
['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]']
1
1
1
1
1
0
1
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0
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Effects of toothbrush design and brushing proficiency on plaque removal.
A single-blind, short-term cross-over clinical trial compared the plaque removal performance of three commercially available manual toothbrushes. A sample of 25 dental hygiene students, 19 to 42 years old, served as participants. On 3 separate occasions, participants were instructed to refrain from toothbrushing or flo...
['Adult', 'Analysis of Variance', 'Cross-Over Studies', 'Dental Plaque', 'Dental Plaque Index', 'Equipment Design', 'Humans', 'Single-Blind Method', 'Toothbrushing']
9,534,367
[['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['C07.793.208.377'], ['E05.318.308.980.438.300.300', 'E06.208.250', 'N05.715.360.300.800.438.300.325', 'N06.850.520.308.980.438.300.300', 'N06.890.160.090'], ['E05.320'...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]']
0
1
1
0
1
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2D NMR of paramagnetic metalloenzymes: cyanide-inhibited horseradish peroxidase.
Two-dimensional (2D) proton NMR correlation spectroscopy, COSY, and nuclear Overhauser spectroscopy, NOESY, have been used to explore the applicability of these methods for the moderately large (42 KDa), paramagnetic cyanide-inhibited derivative of horseradish peroxidase, HRP-CN. The target resonances are those in the ...
['Binding Sites', 'Cyanides', 'Heme', 'Horseradish Peroxidase', 'Magnetic Resonance Spectroscopy', 'Metalloproteins', 'Models, Molecular', 'Protein Conformation']
1,841,693
[['G02.111.570.120'], ['D01.248.497.158.291', 'D01.625.400.100'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['D08.811.682.732.512'], ['E05.196.867.519'], ['D12.776.556'], ['E05.599.595'], ['G02.111.570.820.709']]
['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
0
0
1
1
0
1
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Pathema: a clade-specific bioinformatics resource center for pathogen research.
Pathema (http://pathema.jcvi.org) is one of the eight Bioinformatics Resource Centers (BRCs) funded by the National Institute of Allergy and Infectious Disease (NIAID) designed to serve as a core resource for the bio-defense and infectious disease research community. Pathema strives to support basic research and accele...
['Amino Acid Sequence', 'Animals', 'Bacterial Infections', 'Communicable Diseases', 'Computational Biology', 'Databases, Genetic', 'Genome, Bacterial', 'Humans', 'Information Storage and Retrieval', 'Internet', 'Molecular Sequence Data', 'National Institute of Allergy and Infectious Diseases (U.S.)', 'Sequence Homology...
19,843,611
[['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['C01.150.252'], ['C01.221', 'C23.550.291.531'], ['H01.158.273.180', 'L01.313.124'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['G05.360.340.358.207'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500.750.280', 'L01.470'], ['L01.2...
['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]']
0
1
1
0
0
0
1
1
1
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Mammalian translesion DNA synthesis across an acrolein-derived deoxyguanosine adduct. Participation of DNA polymerase eta in error-prone synthesis in human cells.
alpha-OH-PdG, an acrolein-derived deoxyguanosine adduct, inhibits DNA synthesis and miscodes significantly in human cells. To probe the cellular mechanism underlying the error-free and error-prone translesion DNA syntheses, in vitro primer extension experiments using purified DNA polymerases and site-specific alpha-OH-...
['Acrolein', 'Cell Line', 'Cell Line, Transformed', 'DNA', 'DNA Adducts', 'DNA Primers', 'DNA-Directed DNA Polymerase', 'Deoxyguanosine', 'Humans', 'Models, Chemical', 'Oligonucleotide Probes', 'Oligonucleotides', 'Plasmids', 'Proliferating Cell Nuclear Antigen']
12,584,190
[['D02.047.122'], ['A11.251.210'], ['A11.251.210.172'], ['D13.444.308'], ['D13.444.308.135', 'G05.200.104'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D08.811.913.696.445.308.300'], ['D03.633.100.759.590.454.240', 'D13.570.230.360', 'D13.570.583.454.240'], ['B01.050.150.900.649.313.988.400.112.400.4...
['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
0
1
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STAT1-mediated upregulation of lncRNA LINC00174 functions a ceRNA for miR-1910-3p to facilitate colorectal carcinoma progression through regulation of TAZ.
Several of the thousands of human long noncoding RNAs (lncRNAs) have been functionally characterized, yet their potential involvement in colorectal carcinoma (CRC) remains poorly understood. In present study, we aim to investigate the role of lncRNA LINC00174 in CRC carcinogenesis. We observed that increased expression...
['Cell Line, Tumor', 'Colorectal Neoplasms', 'CpG Islands', 'DNA Methylation', 'Disease Progression', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Kaplan-Meier Estimate', 'MicroRNAs', 'Prognosis', 'RNA Interference', 'RNA, Long Noncoding', 'STAT1 Transcription Fa...
29,729,381
[['A11.251.210.190', 'A11.251.860.180'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G...
['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
1
1
1
1
1
0
1
0
0
0
0
0
1
0
Healthcare-associated Staphylococcus aureus bloodstream infection: length of stay, attributable mortality, and additional direct costs.
This study aimed to determine the excess length of stay, extra expenditures, and attributable mortality to healthcare-associated S. aureus bloodstream infection (BSI) at a teaching hospital in central Brazil. The study design was a matched (1:1) case-control. Cases were defined as patients >13 years old, with a healthc...
['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bacteremia', 'Brazil', 'Case-Control Studies', 'Cross Infection', 'Female', 'Hospital Costs', 'Hospital Mortality', 'Hospitals, Teaching', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Staphylococcal Infections', 'Staphylococcus aureus', 'Young Adult']
23,158,266
[['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['Z01.107.757.176'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C01.248', 'C23.550.291.875.500'], ['N03.219.151.400.687', 'N03.219.262.500...
['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]']
0
1
1
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1
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The vestibular aqueduct sign: Magnetic resonance imaging can detect abnormalities in both ears of patients with unilateral Meniere's disease.
BACKGROUND AND PURPOSE: In patients with Meniere's disease (MD), saccular hydrops can only be studied by magnetic resonance imaging (MRI) at a late stage when the disease is already responsible for moderate to severe hearing loss. However, these patients may also present vestibular aqueduct (VA) abnormalities.MATERIALS...
['Aged', 'Contrast Media', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Meniere Disease', 'Middle Aged', 'Prospective Studies', 'Sensitivity and Specificity', 'Vestibular Aqueduct']
30,423,380
[['M01.060.116.100'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C09.218.568.217.500'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', '...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]']
1
1
1
1
1
0
1
0
0
0
0
1
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0
Aging of a hard-sphere glass: effect of the microscopic dynamics.
We present simulations of the aging of a quasi-hard-sphere glass, with Newtonian and Brownian microscopic dynamics. The system is equilibrated at the desired density (above the glass transition in hard spheres) with short-range attractions, which are removed at t = 0. The structural part of the decay of the density cor...
['Algorithms', 'Biophysics', 'Computer Simulation', 'Glass', 'Hardness', 'Models, Chemical', 'Models, Statistical', 'Oscillometry', 'Phase Transition', 'Physics', 'Time Factors']
21,389,455
[['G17.035', 'L01.224.050'], ['H01.158.344', 'H01.671.100'], ['L01.224.160'], ['J01.637.437'], ['G01.374.647'], ['E05.599.495'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.654'], ['G01.645', 'G02.734'], ['H01.671'], ['G01.910.857']]
['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
0
0
0
0
1
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1
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Random-effects models in investigating the effect of vitamin A in childhood diarrhea.
PURPOSE: By adopting more appropriate and powerful statistical methods that fully exploit longitudinal structure, we re-analyze and extend previously published results from a large community trial to investigate the effect of vitamin A supplementation on the prevalence and severity of diarrhea in young children.METHODS...
['Bayes Theorem', 'Brazil', 'Child, Preschool', 'Data Interpretation, Statistical', 'Diarrhea, Infantile', 'Double-Blind Method', 'Female', 'Humans', 'Infant', 'Linear Models', 'Longitudinal Studies', 'Male', 'Time Factors', 'Vitamin A']
16,303,315
[['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['Z01.107.757.176'], ['M01.060.406.448'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['C23.888.821.214.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Named Groups [M]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]']
0
1
1
1
1
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0
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1
[ISnowmobiles and serious injuries in Western Finnmark].
BACKGROUND: Snowmobiles are increasingly popular. In Western Finnmark, Norway, there is now one snowmobile per five inhabitants, in the rest of Norway only one for each 110 inhabitants. Our clinical impression was that the frequency of injuries had increased. The aim of this study was to describe frequency and severity...
['Accidents', 'Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Female', 'Fractures, Bone', 'Humans', 'Injury Severity Score', 'Male', 'Middle Aged', 'Multiple Trauma', 'Norway', 'Off-Road Motor Vehicles', 'Prospective Studies', 'Wounds and Injuries']
16,327,846
[['N06.850.135'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.940.968.875.500', 'E05.944.600', 'N04.452.859.564.800.500', 'N05.715.360.300.715.500.800.400'], ['M01.060.116.630'], ['C26.640'], ['Z...
['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]']
0
1
1
0
1
0
0
0
0
1
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1
1
Mycotic aneurysm of the petrous portion of the internal carotid artery.
A case of a mycotic aneurysm of the petrous portion of the internal carotid artery is presented. This entity is extremely rare and the problems associated with the diagnosis and clinical management are discussed.
['Adult', 'Aneurysm, Infected', 'Carotid Artery Diseases', 'Carotid Artery, Internal', 'Female', 'Humans', 'Petrous Bone', 'Tomography, X-Ray Computed']
2,921,541
[['M01.060.116'], ['C01.069', 'C14.907.055.131'], ['C10.228.140.300.200', 'C14.907.253.123'], ['A07.015.114.186.200.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.885.681'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.3...
['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
1
0
1
0
0
0
0
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1
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Culex coronator Dyar and Knab: a new Florida species record.
We report the first finding of Culex coronator Dyar and Knab in Florida, based on multiple adult collections from several locations in the western panhandle of Florida. GPS coordinates and habitat descriptions are given and disease implications are discussed. These records extend the known distribution of Cx. coronator...
['Animals', 'Culex', 'Florida']
16,878,419
[['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.225'], ['Z01.107.567.875.750.350']]
['Organisms [B]', 'Geographicals [Z]']
0
1
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0
0
0
0
0
0
0
0
0
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1
VEGF internalization is not required for VEGFR-2 phosphorylation in bioengineered surfaces with covalently linked VEGF.
Vascular endothelial growth factor (VEGF) is known to activate proliferation, migration, and survival pathways in endothelial cells through phosphorylation of VEGF receptor-2 (VEGFR-2). VEGF has been incorporated into biomaterials through encapsulation, electrostatic sequestration, and covalent attachment, but the effe...
['Biocompatible Materials', 'Biomedical Engineering', 'Endocytosis', 'Extracellular Matrix', 'Heparin', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'Immobilized Proteins', 'Optical Tweezers', 'Phosphorylation', 'Protein Stability', 'Solubility', 'Surface Properties', 'Vascular Endothelial Growth Factor A', 'Vas...
21,826,315
[['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['H02.070', 'J01.293.140'], ['G04.417'], ['A11.284.295.310'], ['D09.698.373.400'], ['A11.436.275.682'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.463'], ['E05.650'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['G02.111.700'], ['G02.805'], ['G02.860'],...
['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
0
1
1
0
1
1
0
1
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0
0
0
Quinotrierixin inhibits proliferation of human retinal pigment epithelial cells.
PURPOSE: To investigate the effect of quinotrierixin, a previously reported inhibitor of X-box binding protein 1 (XBP1), on cell proliferation and viability in human retinal pigment epithelium (RPE) cells.METHODS: Subconfluent human RPE cells (ARPE-19) were exposed to quinotrierixin for 16-24 h. Cell proliferation was ...
['Apoptosis', 'Cell Line', 'Cell Proliferation', 'Cell Survival', 'DNA-Binding Proteins', 'Endoplasmic Reticulum Stress', 'Epithelial Cells', 'Humans', 'RNA Splicing', 'Regulatory Factor X Transcription Factors', 'Retinal Pigment Epithelium', 'Rifabutin', 'Thapsigargin', 'Transcription Factor CHOP', 'Transcription Fact...
23,335,849
[['G04.146.954.035'], ['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['D12.776.260'], ['G04.434'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.760.700', 'G03.839.700', 'G05.308.700.700'], ['D12.776.260.950.624', 'D12.776.930.977.624'], ['A09.371.670.500', 'A09.371.729....
['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]']
1
1
1
1
0
0
1
0
0
0
0
0
0
0
Effect of CC chemokines on mediator release from human skin mast cells and basophils.
Chemokines are considered important mediators of various inflammatory processes. In human basophils, different CC chemokines are known to stimulate release of histamine and generation of leukotriene (LT)C4. In the present study, we have evaluated the effect of RANTES (regulated upon activation, normal T cell expressed ...
['Basophils', 'Cells, Cultured', 'Chymases', 'Cytokines', 'Histamine Release', 'Humans', 'Mast Cells', 'Prostaglandin D2', 'Serine Endopeptidases', 'Skin', 'Tryptases']
7,580,286
[['A11.118.637.415.120', 'A11.627.340.120', 'A15.145.229.637.415.120', 'A15.382.490.315.120'], ['A11.251'], ['D08.811.277.656.300.760.103', 'D08.811.277.656.959.350.103'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G12.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.427', 'A15.382.652'],...
['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]']
1
1
0
1
0
0
1
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[Vascular access surgery--technique and teamwork].
With the growing number of diabetics and patients with multiple problems vascular access surgery increases and therapies become more challenging. If haemodialysis is the therapy of choice for renal failure, veins of the patient's upper limbs should be preserved. Autologic fistula of the upper limb--most commonly betwee...
['Arteriovenous Shunt, Surgical', 'Diabetes Complications', 'Humans', 'Radial Artery', 'Renal Dialysis', 'Renal Insufficiency', 'Ultrasonography, Doppler, Duplex']
19,358,419
[['E04.035.087', 'E04.100.814.868.249'], ['C19.246.099'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.740'], ['E02.870.300', 'E02.912.800'], ['C12.777.419.780', 'C13.351.968.419.780'], ['E01.370.350.850.850.850']]
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
0
1
0
0
0
0
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Radiologic-pathologic conference of Children's Hospital Boston: pineal region mass in a neonate.
Prenatal ultrasound examination of a fetus revealed a pineal region mass. Shortly after birth the baby was evaluated with MRI and ultrasound of the brain. The clinical history and the MRI, operative, and histological findings are presented and discussed.
['Boston', 'Brain Neoplasms', 'Craniotomy', 'Diagnosis, Differential', 'Down Syndrome', 'Female', 'Follow-Up Studies', 'Humans', 'Infant, Newborn', 'Magnetic Resonance Imaging', 'Pineal Gland', 'Radiography', 'Teratoma', 'Ultrasonography, Prenatal']
9,323,255
[['Z01.107.567.875.550.510.210', 'Z01.433.210'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E04.525.190'], ['E01.171'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01...
['Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]']
1
1
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1
1
Toward shrimp consumption without chemicals: Combined effects of freezing and modified atmosphere packaging (MAP) on some quality characteristics of Giant Red Shrimp (Aristaeomorpha foliacea) during storage.
The combined effects of freezing and modified atmosphere packaging (MAP) (100% N2 and 50% N2+50% CO2) on some quality characteristics of Giant Red Shrimp (GRS) (Aristaeomorpha foliacea) was studied during 12-month storage. In particular, the quality characteristics determined proximal and gas compositions, melanosis sc...
['Animals', 'Atmosphere', 'Food Packaging', 'Food Preservation', 'Food Storage', 'Freezing', 'Nitrogen', 'Penaeidae', 'Shellfish', 'Vacuum']
26,616,991
[['B01.050'], ['G16.500.275.063', 'N06.230.300.100'], ['J01.576.423.200.375', 'J01.576.423.850.600', 'J01.576.761.400'], ['J01.576.423.850.700'], ['J01.576.423.200.387'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['D01.268.604', 'D01.362.625'], ['B01.050.500.131.365.190.660'], ['G07.203.300.600.875.700', '...
['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]']
0
1
0
1
0
0
1
0
0
1
0
0
1
0
Video-assisted thoracoscopic surgery segmentectomy: a safe and effective procedure.
BACKGROUND: Anatomic sublobar resection is currently being assessed as an alternative to lobectomy for primary lung cancers less than 2 cm in size. Open segmentectomy is a proven oncologic procedure for patients with reduced cardiopulmonary reserve and significant comorbidities. With the increased use of thoracoscopy, ...
['Aged', 'Carcinoma, Non-Small-Cell Lung', 'Cohort Studies', 'Disease-Free Survival', 'Female', 'Follow-Up Studies', 'Hospital Mortality', 'Humans', 'Length of Stay', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Minimally Invasive Surgical Procedures', 'Neoplasm Recurrence, Local', 'Pneumonectomy', 'Postoperative Complica...
20,417,779
[['M01.060.116.100'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06...
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]']
0
1
1
0
1
0
1
0
0
0
0
1
1
0
PAQR3 modulates blood cholesterol level by facilitating interaction between LDLR and PCSK9.
OBJECTIVE: Low-density lipoprotein cholesterol (LDL-C) is the hallmark of atherosclerotic cardiovascular diseases. The hepatic LDL receptor (LDLR) plays an important role in clearance of circulating LDL-C. PCSK9 facilitates degradation of LDLR in the lysosome and antagonizing PCSK9 has been successfully used in the cli...
['Animals', 'Cholesterol', 'Cholesterol, LDL', 'Hep G2 Cells', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Liver', 'Membrane Proteins', 'Mice', 'Proprotein Convertase 9', 'Protein Binding', 'Receptors, LDL']
30,831,144
[['B01.050'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360', 'D12.776.476'], ['A03.62...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]']
1
1
0
1
0
0
1
0
0
0
0
0
0
0
Electrophysiologic features of torsades de pointes: insights from a new isolated rabbit heart model.
INTRODUCTION: The exact electrophysiologic mechanism of torsades de pointes (TdP) is under intense investigation. No isolated animal heart model of this particular arrhythmia exists.METHODS AND RESULTS: In isolated rabbit hearts, TdP was induced by means of bradycardia in the presence of a high concentration of d-sotal...
['Action Potentials', 'Adrenergic beta-Antagonists', 'Animals', 'Arrhythmias, Cardiac', 'Disease Models, Animal', 'Electrocardiography', 'Electrophysiology', 'Heart', 'In Vitro Techniques', 'Magnesium', 'Potassium', 'Rabbits', 'Sotalol', 'Torsades de Pointes']
9,363,818
[['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['B01.050'], ['C14.280.067', 'C23.550.073'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.370.380.240', 'E01.370.405.240'], ['H01.158.344.528', 'H01.158.782.236'], ['A07.541'], ['E05.481']...
['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]']
1
1
1
1
1
0
1
1
0
0
0
0
0
0
Multi trigger responsive, surface active lipid nanovesicle aerosols for improved efficacy of paclitaxel in lung cancer.
The present study focuses on the development of multi-trigger responsive surface active lipid nanovesicles encapsulating paclitaxel with the hypothesis that pulmonary surfactant mimetic lipid vesicles sensitive to temperature and enzyme simultaneously will offer synergistic advantage towards improved therapeutic effica...
['Aerosols', 'Antineoplastic Agents, Phytogenic', 'Cell Line, Tumor', 'Delayed-Action Preparations', 'Humans', 'Lipids', 'Lung Neoplasms', 'Nanocapsules', 'Paclitaxel', 'Surface Properties', 'Treatment Outcome']
22,911,380
[['D20.280.055', 'D26.255.165.055'], ['D27.505.954.248.179'], ['A11.251.210.190', 'A11.251.860.180'], ['D26.255.210', 'E02.319.300.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['D26.255.260.575', 'E02.319.300.380.575', 'J01.637.512.600.575'], ['...
['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]']
1
1
1
1
1
0
1
0
0
1
0
0
1
0
Similarities between insulin, hydrogen peroxide, concanavalin A, and anti-insulin receptor antibody stimulated glucose transport: increase in the number of transport sites.
Plasma membranes from insulin or insulin mimicker (hydrogen peroxide, anti-insulin receptor antibody, and concanavalin A) treated adipocytes showed an increase in glucose transport compared to control cells due to an increase in Vmax and not due to alteration in Km. Arrhenius plots showed no difference in the energy of...
['Adipose Tissue', 'Animals', 'Antibodies', 'Biological Transport, Active', 'Cell Membrane', 'Concanavalin A', 'Glucose', 'Hydrogen Peroxide', 'Insulin', 'Kinetics', 'Receptor, Insulin']
7,043,172
[['A10.165.114'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G03.143.310'], ['A11.284.149'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D09.947.875.359.448'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], [...
['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]']
1
1
0
1
0
0
1
0
0
0
0
0
0
0
Microbubble-enhanced ultrasound for vascular gene delivery.
Progress in cardiovascular gene therapy has been hampered by concerns over the safety and practicality of viral vectors and the inefficiency of current nonviral transfection techniques. We have previously reported that ultrasound exposure (USE) enhances transgene expression in vascular cells by up to 10-fold after nake...
['Albumins', 'Angioplasty, Balloon, Coronary', 'Cell Adhesion', 'Contrast Media', 'Coronary Disease', 'Endothelium, Vascular', 'Fluorocarbons', 'Gene Expression', 'Gene Targeting', 'Genetic Therapy', 'Graft Occlusion, Vascular', 'Humans', 'Hydrogen Peroxide', 'Indicators and Reagents', 'Liposomes', 'Luciferases', 'Musc...
11,175,314
[['D12.776.034'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['G04.022'], ['D27.505.259.500', 'D27.720.259'], ['C14.280.647.250', 'C14.907.585.250'], ['A07.015.7...
['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]']
1
1
1
1
1
0
1
1
0
1
0
0
0
0
Impact of Preoperative Atrial Fibrillation on Postoperative Thromboembolic Events After Left Ventricular Assist Device Implantation.
BACKGROUND: The incidence of atrial fibrillation (AF) among patients undergoing left ventricular assist device (LVAD) implantation is high. However, the impact of AF on clinical outcomes has not been clarified. We reviewed our 9-year experience of continuous flow (CF) LVADs to determine the impact of preoperative AF on...
['Adult', 'Aged', 'Anticoagulants', 'Atrial Appendage', 'Atrial Fibrillation', 'Disease Susceptibility', 'Equipment Failure', 'Female', 'Heart Failure', 'Heart-Assist Devices', 'Humans', 'Incidence', 'Intensive Care Units', 'Kaplan-Meier Estimate', 'Length of Stay', 'Male', 'Middle Aged', 'Proportional Hazards Models',...
27,469,338
[['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.502.119'], ['A07.541.358.100'], ['C14.280.067.198', 'C23.550.073.198'], ['C23.550.291.687', 'G07.100.250'], ['E05.325'], ['C14.280.434'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]']
1
1
1
1
1
0
1
0
0
0
0
1
1
0
A three gene-based risk score predicts prognosis of resected non-small-cell lung cancer.
BACKGROUND: To study the prognosis-predicting value of a risk score based on phosphorylated At (p-Akt), vascular endothelial growth factor (VEGF), and Nin one binding (NOB1) expression in patients with resected non-small-cell lung cancer (NSCLC).METHODS: A prospective cohort among 98 consecutive patients with resected ...
['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Carcinoma, Non-Small-Cell Lung', 'Decision Support Techniques', 'Disease-Free Survival', 'Female', 'Humans', 'Immunohistochemistry', 'Kaplan-Meier Estimate', 'Lung Neoplasms', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm S...
26,884,885
[['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E05.245', 'L01.313.500.750.190'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.75...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]']
0
1
1
1
1
0
1
1
0
0
1
1
1
0
Simultaneous recording of mechanical and intracellular electrical activity in guinea-pig urinary bladder smooth muscle: a comparison with human detrusor contraction.
OBJECTIVES: To study the relationship between the electrical and mechanical activity of guinea-pig detrusor muscle and compare this with the results obtained in human tissue. The guinea pig is the most used model to study the electrical basis of human bladder contraction.METHODS: We simultaneously recorded the mechanic...
['Animals', 'Evoked Potentials', 'Female', 'Guinea Pigs', 'In Vitro Techniques', 'Male', 'Membrane Potentials', 'Models, Animal', 'Muscle Contraction', 'Muscle, Smooth', 'Receptors, Muscarinic', 'Urinary Bladder']
11,018,641
[['B01.050'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.992.550'], ['E05.481'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['E05.598'], ['G11.427.494'], ['A02.633.570', 'A10.690.467'], ['D12.776.543.750.695.475', 'D12.776.543.750.720.360.500'], ['A05.810.890']]
['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Feedlot performance and carcass characteristics of Holstein steers as affected by source of dietary protein and level of ruminally protected lysine and methionine.
The objective of this study was to determine the effects of source of dietary CP and level of ruminally protected lysine and methionine (RPLM) on feedlot performance and carcass characteristics of Holstein steers during a growing-finishing trial (266 d). A total of 168 Holstein steers (182.7 +/- 27.5 kg) were used in a...
['Animal Feed', 'Animals', 'Body Composition', 'Cattle', 'Dietary Proteins', 'Food, Fortified', 'Lysine', 'Male', 'Meat', 'Methionine', 'Plant Proteins, Dietary', 'Soybean Proteins', 'Urea']
8,655,422
[['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['B01.050.150.900.649.313.500.380.271'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.300.515', 'J02.500.515'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['G07.203.300.600', 'J02.500.600...
['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]']
0
1
0
1
0
0
1
0
0
1
0
0
0
0
Alfentanil/etomidate anaesthesia for endolaryngeal microsurgery.
Anaesthesia for laryngeal microsurgery by laser was conducted using etomidate and alfentanil. Patients' lungs were ventilated with air to avoid the danger of fire during the use of the laser. Thirty one patients received fentanyl/droperidol or pethidine for premedication. Anaesthesia was induced with etomidate 300 micr...
['Acid-Base Equilibrium', 'Adult', 'Alfentanil', 'Analgesics, Opioid', 'Anesthesia, General', 'Anesthesia, Intravenous', 'Carbon Dioxide', 'Etomidate', 'Fentanyl', 'Hemodynamics', 'Humans', 'Imidazoles', 'Laryngeal Diseases', 'Laser Therapy', 'Microsurgery', 'Middle Aged', 'Oxygen', 'Partial Pressure', 'Positive-Pressu...
6,135,369
[['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['M01.060.116'], ['D03.383.621.265.100'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E03.155.197'], ['E03.155.308'], ['D01.200.200', 'D01.362.150', 'D01.650.550....
['Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]']
0
1
1
1
1
0
1
0
0
0
0
1
0
0
Testing a theory of organizational culture, climate and youth outcomes in child welfare systems: a United States national study.
Theories of organizational culture and climate (OCC) applied to child welfare systems hypothesize that strategic dimensions of organizational culture influence organizational climate and that OCC explains system variance in youth outcomes. This study provides the first structural test of the direct and indirect effects...
['Adolescent', 'Caregivers', 'Child', 'Child Behavior', 'Child Welfare', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Models, Theoretical', 'Multilevel Analysis', 'Organizational Culture', 'Outcome Assessment, Health Care', 'United States']
24,094,999
[['M01.060.057'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['M01.060.406'], ['F01.145.179'], ['I01.880.787.293'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.599'], ['N06.850.520.830.562'], ['N04.452.606'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.57...
['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]']
0
1
0
0
1
1
0
1
1
0
0
1
1
1
On the mechanism of NO release from sydnonimines.
The vasodilator and antiaggregatory properties of sydnonimines like SIN-1 are thought to be due to their marked stimulatory action on soluble guanylate cyclase. Enzyme activation and consecutive cyclic GMP accumulation is mediated by the liberation of nitric oxide (NO) from the open-ring A forms of sydnonimines. The pu...
['Animals', 'Enzyme Activation', 'Guanylate Cyclase', 'Liver', 'Molsidomine', 'Nitrates', 'Nitric Oxide', 'Nitrites', 'Oxygen Consumption', 'Rats', 'Superoxides']
2,484,692
[['B01.050'], ['G02.111.263', 'G03.328'], ['D08.811.520.650.600', 'D12.644.360.350', 'D12.776.476.350'], ['A03.620'], ['D03.383.129.462.580.693.450', 'D03.383.533.640.362'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D01.248.497...
['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]']
1
1
0
1
0
0
1
0
0
0
0
0
0
0
Upregulation of erythropoietin receptor during postnatal and postpneumonectomy lung growth.
Circulating erythropoietin (EPO) stimulates erythrocytosis, whereas organ-specific local EPO receptor (EPOR) expression has been linked to angiogenesis, tissue growth, and development. On the basis of the observation of concurrent enhancement of lung growth and erythrocyte production during exposure to chronic hypoxia,...
['Aging', 'Animals', 'Animals, Newborn', 'Cell Membrane', 'Cytosol', 'Dogs', 'Immunohistochemistry', 'Lung', 'Pneumonectomy', 'Receptors, Erythropoietin', 'Up-Regulation']
15,286,000
[['G07.345.124'], ['B01.050'], ['B01.050.050.282'], ['A11.284.149'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.23...
['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]']
1
1
0
1
1
0
1
1
0
0
0
0
0
0
Genomic expression changes induced by topical N-acetyl glucosamine in skin equivalent cultures in vitro.
N-acetyl glucosamine (NAG) has been shown to be effective in reducing the appearance of hyperpigmented spots. From published in vitro mechanistic testing, glucosamine inhibits enzymatic glycosylation, a required processing step in converting inactive human pro-tyrosinase to the active tyrosinase, a key enzyme in the pr...
['Acetylglucosamine', 'Administration, Cutaneous', 'Dermatologic Agents', 'Dose-Response Relationship, Drug', 'Gene Expression Regulation', 'Humans', 'Hyperpigmentation', 'Melanins', 'Skin', 'Tissue Culture Techniques']
18,047,607
[['D09.067.342.531.050'], ['E02.319.267.120.060'], ['D27.505.954.444'], ['G07.690.773.875', 'G07.690.936.500'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.621.430'], ['D12.125.072.050.875.379', 'D23.767.620'], ['A17.815'], ['E05.481.500.617']]
['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]']
1
1
1
1
1
0
1
0
0
0
0
0
0
0
SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis.
SEK1 (MKK4/JNKK) is a mitogen-activated protein kinase activator that has been shown to participate in vitro in two stress-activated cascades terminating with the SAPK and p38 kinases. To define the role of SEK1 in vivo, we studied stress-induced signaling in SEK1(-/-) embryonic stem and fibroblast cells and evaluated ...
['Animals', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Fibroblasts', 'Gene Expression Regulation, Developmental', 'Liver', 'MAP Kinase Kinase 4', 'Mice', 'Mice, Knockout', 'Mitogen-Activated Protein Kinase Kinases', 'Protein Kinases', 'Signal Transduction', 'Stem Cells']
9,618,507
[['B01.050'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['A11.329.228'], ['G05.308.310'], ['A03.620'], ['D08.811.913.696.620.682.700.565.400', 'D08.811.913.696.620.682.725.200.400', 'D12.644.360.440.400', 'D12.776.476.440.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]']
1
1
0
1
0
0
1
0
0
0
0
0
0
0
Management of advanced pancreatic cancer in daily clinical practice.
PURPOSE: The aim of this outcome study was to evaluate the management of advanced pancreatic cancer in a real-world clinical practice; few such experiences have been reported in the literature.METHODS: A retrospective analysis was performed of all consecutive patients with advanced pancreatic ductal adenocarcinoma foll...
['Adult', 'Aged', 'Aged, 80 and over', 'Antimetabolites, Antineoplastic', 'Antineoplastic Combined Chemotherapy Protocols', 'Deoxycytidine', 'Disease Management', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Organoplatinum Compounds', 'Pain', 'Pancreatic Neoplasms', 'Prognosis', 'Retrospective Studi...
26,429,644
[['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D03.383.742.680.245.500', 'D13.570.230.329', 'D13.570.685.245.500'], ['N04.590.607'], ['E05.318.372.500.750.249', 'N05.715.3...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]']
0
1
1
1
1
1
1
0
0
0
0
1
1
0
Upregulation of miR-23a-27a-24-2 cluster induces caspase-dependent and -independent apoptosis in human embryonic kidney cells.
miRNAs have emerged as important players in the regulation of gene expression and their deregulation is a common feature in a variety of diseases, especially cancer. Currently, many efforts are focused on studying miRNA expression patterns, as well as miRNA target validation. Here, we show that the over expression of m...
['Animals', 'Apoptosis', 'Caspases', 'Cell Line', 'Cell Line, Tumor', 'Cytochromes c', 'Gene Expression Regulation, Developmental', 'Humans', 'Kidney', 'Membrane Potentials', 'MicroRNAs', 'Rats', 'Tumor Necrosis Factor-alpha', 'Up-Regulation']
19,513,126
[['B01.050'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['D08.244.286.100', 'D12.776.422.220.286.100'], ['G05.308.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A0...
['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]']
1
1
0
1
0
0
1
0
0
0
0
0
0
0
[Rademaker and Garcin syndrome associated with pallidal calcifications].
We report gait abnormalities with exaggerated support against gravity in a 76 year-old woman. This exaggeration, and its demonstration by ankle dorsiflexion in supine position, was first described by Rademaker and Garcin (1933) as probably resulting from cerebellar and brainstem lesions. In the present case, quantitati...
['Aged', 'Basal Ganglia Diseases', 'Brain Diseases', 'Calcinosis', 'Electromyography', 'Female', 'Gait', 'Globus Pallidus', 'Humans', 'Radiography', 'Syndrome']
1,494,726
[['M01.060.116.100'], ['C10.228.140.079'], ['C10.228.140'], ['C18.452.174.130'], ['E01.370.405.255', 'E01.370.530.255'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['A08.186.211.200.885.287.249.487.397'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['C23.550.288.500']]
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]']
1
1
1
0
1
0
1
0
0
0
0
1
0
0
Changes in brain alpha-adrenergic receptors after alpha-methyldopa administration to spontaneously hypertensive rats.
The hypotensive action of methyldopa has been linked to production of the metabolites methyldopamine and methylnorepinephrine in brain. We have studied the effect of long-term (72 hour) intravenous infusions of methyldopa to awake restrained spontaneously hypertensive rats and normotensive Wistar-Kyoto control animals ...
['Animals', 'Brain', 'Deoxyepinephrine', 'Dopamine', 'Hypertension', 'Hypothalamus', 'Male', 'Medulla Oblongata', 'Methyldopa', 'Nordefrin', 'Norepinephrine', 'Pons', 'Rats', 'Rats, Inbred SHR', 'Rats, Inbred WKY', 'Receptors, Adrenergic, alpha']
6,094,347
[['B01.050'], ['A08.186.211'], ['D02.092.311.342.300', 'D02.092.311.461.200', 'D02.455.426.559.389.657.166.175.342.300', 'D02.455.426.559.389.657.166.175.461.200'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['C14.907.489'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['A...
['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]']
1
1
1
1
0
0
0
0
0
0
0
0
0
0
Prevalence of different strains of Candida albicans in patients with denture-induced stomatitis.
Eighteen resistogram strains of Candida albicans were found among isolates obtained from 10 oral sites sampled prior to treatment in 22 patients with denture stomatitis. Eight strains were isolated from single patients, but two were found in four patients and one was found in five patients. Fifteen of the 18 strains we...
['Candida albicans', 'Candidiasis, Oral', 'Humans', 'Mouth Mucosa', 'Stomatitis', 'Stomatitis, Denture']
6,367,101
[['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['C01.150.703.160.180', 'C07.465.130'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.615.550.599', 'A14.549.512'], ['C07.465.864'], ['C07.465.864.875']]
['Organisms [B]', 'Diseases [C]', 'Anatomy [A]']
1
1
1
0
0
0
0
0
0
0
0
0
0
0
Thoracic hyperextension injury with opening wedge distraction fracture in DISH -consideration of surgical strategy based on intraoperative pathological findings.
Diffuse idiopathic skeletal hyperostosis (DISH) is a well-recognized disease characterized by calcifications and ossifications of the entheses mainly in the spine. Patients with DISH are prone to sustaining spinal injuries even after minor trauma because of the long-lever arm mechanism induced by any type of force acti...
['Aged', 'Female', 'Fracture Fixation, Internal', 'Humans', 'Hyperostosis, Diffuse Idiopathic Skeletal', 'Lumbar Vertebrae', 'Monitoring, Intraoperative', 'Spinal Fractures', 'Thoracic Vertebrae']
32,178,994
[['M01.060.116.100'], ['E04.555.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.540.410', 'C05.116.900.815.651'], ['A02.835.232.834.519'], ['E01.370.520.510', 'E04.510'], ['C26.117.500.500', 'C26.404.812'], ['A02.835.232.834.892']]
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]']
1
1
1
0
1
0
0
0
0
0
0
1
0
0
First clinical experience with Molecular Adsorbent Recirculating System (MARS) in six patients with severe acute on chronic liver failure.
UNLABELLED: Despite recent advances in general supportive care, the mortality rate of patients with severe liver insufficiency remains high. Recently a new artificial liver support system MARS has been used for selective removal of albumin-bound toxins.AIM: To assess the safety and efficacy of MARS treatment in patient...
['Acute Disease', 'Adult', 'Blood Coagulation Disorders', 'Chronic Disease', 'Female', 'Humans', 'Liver Failure, Acute', 'Liver Transplantation', 'Male', 'Middle Aged', 'Prospective Studies', 'Renal Dialysis', 'Sorption Detoxification', 'Treatment Outcome']
12,220,307
[['C23.550.291.125'], ['M01.060.116'], ['C15.378.100'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.308.500.750'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.52...
['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
0
1
1
0
1
0
0
0
0
0
0
1
1
0
Factors associated with initiation on clozapine and on other antipsychotics among Medicaid enrollees.
OBJECTIVE: Demographic and clinical factors associated with starting clozapine and other antipsychotics were examined.METHODS: New York State Medicaid claims from 2008 to 2009 identified individuals with a schizophrenia spectrum disorder, continuous Medicaid eligibility during the study, and at least one clinic service...
['Adult', 'African Americans', 'Antipsychotic Agents', 'Clozapine', 'European Continental Ancestry Group', 'Female', 'Hispanic Americans', 'Humans', 'Insurance Claim Review', 'Logistic Models', 'Male', 'Medicaid', 'Middle Aged', 'New York', 'Schizophrenia', 'United States', 'Young Adult']
23,117,514
[['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['D03.633.300.240.220'], ['M01.686.508.400'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.215'], ['E05.318.740.500.525', 'E...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]']
0
1
0
1
1
1
0
0
0
0
0
1
1
1
Cloning and sequencing of Vibrio cholerae mannose-sensitive haemagglutinin pilin gene: localization of mshA within a cluster of type 4 pilin genes.
The mannose-sensitive haemagglutinin (MSHA) pilus that is associated with Vibrio cholerae strains of El Tor biotype has been shown to be a potential colonization factor and protective antigen. The gene encoding the structural subunit of MSHA pili was cloned from size-fractionated SacI-cleaved chromosomal DNA in the exp...
['Amino Acid Sequence', 'Antigens, Bacterial', 'Bacterial Adhesion', 'Bacterial Proteins', 'Base Sequence', 'Cloning, Molecular', 'Endopeptidases', 'Escherichia coli', 'Fimbriae Proteins', 'Fimbriae, Bacterial', 'Genes, Bacterial', 'Hemagglutinins', 'Mannose', 'Mannose-Binding Lectin', 'Molecular Sequence Data', 'Multi...
7,984,085
[['G02.111.570.060', 'L01.453.245.667.060'], ['D23.050.161'], ['G06.099.050'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D08.811.277.656.300'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.120.425', 'D12.776.543.100.300'], ['A11.284.180.285',...
['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]']
1
1
0
1
1
0
1
0
0
0
1
0
0
0
Reactive changes in pulmonary parenchyma after bilobectomy: a scanning electron microscopic investigation.
This study describes the morphology of the adaptive response of the pulmonary parenchyma after the resection of lung tissue. Rats aged 23 days were subjected to the bilobectomy of the right upper and middle lobes representing 25% of the total lung volume. On the postoperative Days 1, 4, 6, 9, 12, 18, and 30, the lungs ...
['Animals', 'Male', 'Microscopy, Electron, Scanning', 'Models, Biological', 'Pneumonectomy', 'Pulmonary Alveoli', 'Rats', 'Time Factors']
7,169,060
[['B01.050'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E05.599.395'], ['E04.620', 'E04.928.600.600'], ['A04.411.715'], ['B01.050.150.900.649.313.992.635.505.700'], ['G01.910.857']]
['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]']
1
1
0
0
1
0
1
0
0
0
0
0
0
0
A case-control study of laparoscopy-assisted and open distal gastrectomy for advanced gastric cancer.
BACKGROUND: The application of laparoscopy-assisted gastric surgery has been increasing rapidly for the treatment of early gastric cancer. However, there were few reports of laparoscopic surgery in the management of advanced gastric cancer (AGC), especially with T3 depth of invasion. The aim of this study was to compar...
['Adult', 'Female', 'Follow-Up Studies', 'Gastrectomy', 'Humans', 'Laparoscopy', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Retrospective Studies', 'Stomach Neoplasms', 'Treatment Outcome', 'Young Adult']
20,967,510
[['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['E01.789.625'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]']
0
1
1
0
1
0
0
0
0
0
0
1
1
0
Contribution of glomerular filtration rate to 10-year cardiovascular and mortality risk among hypertensive adults: Tehran lipid and glucose study.
The authors tested the hypotheses that (1) estimated glomerular filtration rate (eGFR) predicts cardiovascular disease (CVD) or mortality risk among hypertensive patients, (2) associations are curvilinear, and (3) diabetes modifies these associations. Data from a 10-year follow-up of 3179 hypertensive patients 18 years...
['Adult', 'Aged', 'Cardiovascular Diseases', 'Diabetes Complications', 'Female', 'Follow-Up Studies', 'Glomerular Filtration Rate', 'Humans', 'Hypertension', 'Incidence', 'Iran', 'Male', 'Middle Aged', 'Proportional Hazards Models', 'Prospective Studies', 'Residence Characteristics', 'Risk Factors', 'Surveys and Questi...
23,614,851
[['M01.060.116'], ['M01.060.116.100'], ['C14'], ['C19.246.099'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.85...
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]']
0
1
1
0
1
0
1
0
0
0
0
1
1
1
Broxaterol: a double-blind clinical trial comparing broxaterol and salbutamol.
10 patients with reversible bronchospasm received by the oral route in a double-blind fashion broxaterol, Z. 1170, 0.250 and 0.500 mg in comparison with salbutamol 4 mg as base and a placebo. Measurements of FEV1, heart rate and arterial pressure were performed before and 0.5, 1, 2, 4, 6 h after each treatment. Z. 1170...
['Adrenergic beta-Agonists', 'Adult', 'Aged', 'Albuterol', 'Asthma', 'Blood Pressure', 'Bronchitis', 'Clinical Trials as Topic', 'Double-Blind Method', 'Female', 'Forced Expiratory Volume', 'Heart Rate', 'Humans', 'Isoxazoles', 'Male', 'Middle Aged', 'Oxazoles', 'Pulse', 'Random Allocation', 'Spirometry', 'Time Factors...
2,861,630
[['D27.505.519.625.050.100.200', 'D27.505.696.577.050.100.200'], ['M01.060.116'], ['M01.060.116.100'], ['D02.033.100.291.057', 'D02.092.063.291.057', 'D02.092.471.683.061'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C01.748.099', 'C08.127.446...
['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]']
0
1
1
1
1
0
1
0
0
0
0
1
1
0
Invasive sino-orbital aspergillosis: surgical decisions and dilemmas.
Invasive aspergillosis, one of the common paranasal sinus fungal infections, often secondarily involves the orbit. We report six such cases with orbital extension, all occurring in apparently immunocompetent hosts, to specifically address the difficult diagnostic and therapeutic issues involved. Limited biopsy procedur...
['Adult', 'Amphotericin B', 'Antifungal Agents', 'Aspergillosis', 'Biopsy', 'Decision Making', 'Female', 'Humans', 'Itraconazole', 'Male', 'Middle Aged', 'Nasal Mucosa', 'Orbit Evisceration', 'Orbital Diseases', 'Paranasal Sinus Diseases', 'Postoperative Care', 'Tomography, X-Ray Computed']
12,816,217
[['M01.060.116'], ['D02.540.576.500.500'], ['D27.505.954.122.136'], ['C01.150.703.080'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.799....
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]']
1
1
1
1
1
1
0
0
0
0
0
1
1
0
Isolation of a Suppressor-mutator/Enhancer-like transposable element, Tpn1, from Japanese morning glory bearing variegated flowers.
The Japanese morning glory has an extensive history of genetic studies. Many mutants in the colors and shapes of its flowers and leaves have been isolated since the 17th century, and more than 200 genetic loci have been localized for the 10 linkage groups. They include over 20 mutable loci, several with variegated flow...
['Alcohol Oxidoreductases', 'Base Sequence', 'Cloning, Molecular', 'Crosses, Genetic', 'DNA Transposable Elements', 'Exons', 'Genomic Library', 'Germ Cells', 'Introns', 'Molecular Sequence Data', 'Mutagenesis', 'Plants', 'Polymerase Chain Reaction', 'Repetitive Sequences, Nucleic Acid']
8,180,498
[['D08.811.682.047'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['E05.393.281'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['G05.360.340.024.340.137.232'], ['G05.360.325.425', 'G05.360.340.425'], ['A05.360.490', 'A11.497']...
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]']
1
1
0
1
1
0
1
0
0
0
1
0
0
0
Establishing partnerships with social services agencies for community health education.
Nursing education is currently faced with many changes in both the academic and clinical environments. A significant challenge is to provide students with meaningful clinical placements. Experiences in clinical placements allow students to test assessment, critical thinking, communication, and decision-making skills in...
['Aged', 'Boston', 'Clinical Clerkship', 'Community Health Centers', 'Community Health Nursing', 'Cooperative Behavior', 'Housing for the Elderly', 'Humans', 'Interinstitutional Relations', 'Social Work']
11,985,208
[['M01.060.116.100'], ['Z01.107.567.875.550.510.210', 'Z01.433.210'], ['I02.358.105'], ['N02.278.035.128'], ['H02.478.676.150', 'N02.421.143.150'], ['F01.145.813.115'], ['J03.340.260', 'N01.224.791.400.410', 'N06.230.150.360.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.822.400'], ['I01.880.792', 'N...
['Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]']
0
1
0
0
0
1
0
1
1
1
0
1
1
1
Tolerance to Noninherited Maternal Antigens Allows Successful Second Kidney Transplantation: A Case Report.
The 2-way traffic of cells between mother and fetus may introduce noninherited maternal HLA antigens (NIMAs) from the mother to her fetus and expose her to the inherited paternal antigens presented on fetal cells. While contact of maternal immune system with paternal antigens leads to sensitization and development of a...
['Adult', 'Female', 'Graft Survival', 'HLA Antigens', 'Humans', 'Immune Tolerance', 'Isoantibodies', 'Kidney Transplantation', 'Male', 'Mothers', 'Reoperation', 'Siblings', 'Tissue Donors']
30,879,582
[['M01.060.116'], ['G12.875.545.340'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.535.425'], ['D12.776.124.486.485.114.664', 'D12.776.124.790.651.114.664', 'D12.776.377.715.548.114.664'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['F01.829.263.500...
['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]']
0
1
0
1
1
1
1
0
1
0
0
1
0
0
Adaption of luting cement to enamel, dentin and restorative material.
Thirty-two teeth with artificial crowns cemented with four different cements were sectioned and the cementing interfaces were studied by means of a replica technique. Scanning electronic microscopic examination of the replicas demonstrated that slits occurred in all specimens either at the cement/tooth interface, the c...
['Adhesiveness', 'Composite Resins', 'Crowns', 'Dental Cements', 'Dental Enamel', 'Dentin', 'Denture Retention', 'Humans', 'Polycarboxylate Cement', 'Zinc Oxide-Eugenol Cement', 'Zinc Phosphate Cement']
354,310
[['G02.860.139'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.780.346.250', 'E07.695.190.088'], ['D25.339.291', 'J01.637.051.339.291'], ['A14.549.167.900.255'], ['A14.549.167.900.280'], ['E06.780.346.760.550'], ['B01.050.150.900.649....
['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]']
1
1
0
1
1
0
1
0
0
1
0
0
0
0
Sphingosine-1-phosphate induces VEGF-C expression through a MMP-2/FGF-1/FGFR-1-dependent pathway in endothelial cells in vitro.
AIM: To investigate whether sphingosine-1-phosphate (S1P), a potent angiogenic factor, induced vascular endothelial growth factor-C (VEGF-C) expression in endothelial cells in vitro and to examine its underlying mechanisms.METHODS: Human umbilical vein endothelial cells (HUVECs) were examined. VEGF-C mRNA expression in...
['Cell Culture Techniques', 'Down-Regulation', 'Enzyme-Linked Immunosorbent Assay', 'Fibroblast Growth Factor 1', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'Lysophospholipids', 'Matrix Metalloproteinase 2', 'Phosphorylation', 'RNA, Small Interfering', 'Real-Time Polymerase Chain Reaction', 'Receptor, Fibrobla...
23,377,549
[['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D12.644.276.624.110', 'D12.776.467.624.110', 'D23.529.624.110'], ['A11....
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Individual Health Budgets in Mental Health: Results of Its Implementation in the Friuli Venezia Giulia Region, Italy.
BACKGROUND: Individual Health Budget (IHB) is an intervention for recovery in mental health services, providing personalized care for subjects with severe disorders and complex needs. Little is known on its effectiveness and on the criteria for its delivery.METHODS: A total of 67 IHB beneficiaries and 61 comparators we...
['Adult', 'Aged', 'Budgets', 'Female', 'Humans', 'Italy', 'Male', 'Mental Disorders', 'Mental Health', 'Mental Health Services', 'Middle Aged', 'Young Adult']
32,668,599
[['M01.060.116'], ['M01.060.116.100'], ['N03.219.463.060'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['F03'], ['F02.418', 'N01.400.500'], ['F04.408', 'N02.421.461'], ['M01.060.116.630'], ['M01.060.116.815']]
['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]']
0
1
0
0
0
1
0
0
0
0
0
1
1
1
Arthroscopic treatment for symptomatic lateral discoid meniscus: The effects of different ages, groups and procedures on surgical outcomes.
BACKGROUND: There is a paucity of literature regarding the results of arthroscopic saucerization, with or without stabilization, for lateral discoid meniscus (LDM) in children, and differences in clinical outcomes between adults and children. The purpose of this study was to compare the clinical outcomes following arth...
['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Arthroscopy', 'Child', 'Female', 'Follow-Up Studies', 'Humans', 'Knee Joint', 'Male', 'Menisci, Tibial', 'Middle Aged', 'Osteoarthritis, Knee', 'Patient Reported Outcome Measures', 'Young Adult']
30,115,588
[['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.83...
['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]']
1
1
1
0
1
0
0
0
0
0
0
1
1
0
The importance of DR4Dw4 beta chain residues 70, 71, and 86 in peptide binding and T cell recognition.
The expression of specific alleles of the human HLA-DR locus is associated with increased risk for the development of rheumatoid arthritis. Examination of the amino acid sequence of the DR beta chain has revealed that risk for RA correlates with a cluster of polymorphic residues located between positions 67 and 86, and...
['Amino Acid Sequence', 'HLA-DR4 Antigen', 'Hemagglutinins, Viral', 'Humans', 'Ligands', 'Lymphocyte Activation', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Orthomyxoviridae', 'Peptides', 'Polymorphism, Genetic', 'Receptors, Antigen, T-Cell', 'Structure-Activity Relationship', 'T-Lymphocytes']
7,743,549
[['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.395.550.509.400.440.400.040', 'D12.776.543.550.440.400.440.400.040', 'D23.050.301.500.400.400.440.400.040', 'D23.050.301.500.450.400.440.389.937', 'D23.050.705.552.410.400.440.389.040', 'D23.050.705.552.450.400.440.389.937'], ['D12.776.964.970.880.345', 'D23.050.32...
['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]']
1
1
0
1
1
0
1
0
0
0
1
0
0
0
Toxic epidermal necrolysis: analysis of clinical course and SCORTEN-based comparison of mortality rate and treatment modalities in Korean patients.
Toxic epidermal necrolysis (TEN) is a rare, life-threatening, drug-induced cutaneous reaction. We herein report our experience regarding causes, clinical course, treatment and sequelae of TEN in Korean patients. In addition, we used the SCORTEN, a severity-of-illness score for TEN, to compare the predicted and actual m...
['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Female', 'Glucocorticoids', 'Humans', 'Immunoglobulins, Intravenous', 'Male', 'Middle Aged', 'Severity of Illness Index', 'Stevens-Johnson Syndrome', 'Survival Rate']
16,396,796
[['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393.536', 'D12.776.124.486.485.114.632', 'D12.776.124.790.651.114.632', 'D...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]']
0
1
1
1
1
0
0
0
0
0
0
1
1
0
[3H]tiagabine binding to GABA uptake sites in human brain.
The binding of [3H]tiagabine ((RS-1-(4,4-(3-methyl-2-thienyl)-3-butenyl)-3-piperidine carboxylic acid) to homogenates of frozen post-mortem human brain has been characterized. Inhibition experiments with gamma-aminobutyric acid (GABA), GABA uptake inhibitors, ligands active at postsynaptic GABA receptors and receptors ...
['Adult', 'Aged', 'Aged, 80 and over', 'Brain', 'Carrier Proteins', 'Female', 'GABA Plasma Membrane Transport Proteins', 'Humans', 'Male', 'Membrane Proteins', 'Membrane Transport Proteins', 'Middle Aged', 'Neurotransmitter Uptake Inhibitors', 'Nipecotic Acids', 'Organic Anion Transporters', 'Tiagabine']
10,642,842
[['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A08.186.211'], ['D12.776.157'], ['D12.776.157.530.450.625.139', 'D12.776.157.530.562.374.750', 'D12.776.543.585.450.625.139', 'D12.776.543.585.562.374.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543'], ['D12.776.157.530', 'D12.776.5...
['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]']
1
1
0
1
0
0
0
0
0
0
0
1
0
0
An epidemiologic study on aging and dysphagia in the acute care hospitalized population: 2000-2007.
OBJECTIVES: To describe total and yearly demographic trends relative to aging, dysphagia referral rates and oral feeding status in hospitalized patients from 2000 through 2007.METHODS: We evaluated a prospective, consecutive, referred sample of 4,038 hospitalized patients in an urban, tertiary, acute care teaching hosp...
['Acute Disease', 'Age Distribution', 'Aged, 80 and over', 'Aging', 'Deglutition', 'Deglutition Disorders', 'Diagnosis-Related Groups', 'Eating', 'Endoscopy, Digestive System', 'Female', 'Hospitalization', 'Hospitals, Teaching', 'Humans', 'Incidence', 'Male', 'Referral and Consultation', 'Risk Factors']
19,707,014
[['C23.550.291.125'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100.080'], ['G07.345.124'], ['G10.261.178'], ['C06.405.117.119', 'C09.775.174'], ['N03.219.521.710.305.200.080'], ['G07.203.650.283', 'G10.261.330'], ['E01.370.372.250', 'E01.370.388.250.250', 'E04.210.240', 'E04.502.250.250'], [...
['Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]']
0
1
1
0
1
0
1
0
1
0
0
1
1
0
Skittle: a 2-dimensional genome visualization tool.
BACKGROUND: It is increasingly evident that there are multiple and overlapping patterns within the genome, and that these patterns contain different types of information--regarding both genome function and genome history. In order to discover additional genomic patterns which may have biological significance, novel str...
['Alu Elements', 'Centromere', 'Chromosomes, Human, Y', 'Computational Biology', 'Genetic Variation', 'Genome', 'Genomics', 'Humans', 'Internet', 'Nucleotides', 'Pattern Recognition, Automated', 'Sequence Alignment', 'Sequence Analysis, DNA', 'Software', 'Tandem Repeat Sequences', 'User-Computer Interface']
20,042,093
[['G02.111.570.080.708.330.800.800.050', 'G05.360.080.708.330.800.800.050', 'G05.360.340.024.425.800.800.050'], ['A11.284.430.106.279.345.190.160.165', 'G05.360.160.165'], ['A11.284.187.520.300.505.757', 'A11.284.187.865.983.500', 'G05.360.162.520.300.505.757', 'G05.360.162.865.983.500'], ['H01.158.273.180', 'L01.313.1...
['Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
0
1
1
0
1
1
0
0
1
0
0
0
Morbihan Disease Treatment: Two Case Reports and a Systematic Literature Review.
PURPOSE: To assess the effectiveness of treatments for Morbihan disease.METHODS: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a systematic review of the literature was performed on April 1, 2018, using PubMed, Google Scholar, and Excerpta Medica dataBASE with terms used t...
['Administration, Topical', 'Adult', 'Anti-Infective Agents', 'Dermatologic Agents', 'Female', 'Glucocorticoids', 'Humans', 'Isotretinoin', 'Lymphedema', 'Male', 'Metronidazole', 'Middle Aged', 'Prednisone', 'Rosacea']
30,252,748
[['E02.319.267.120'], ['M01.060.116'], ['D27.505.954.122'], ['D27.505.954.444'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.326.271.665.202.495.325', 'D02.455.426.392.368.367.379.249.700.325', 'D02.455.849.131.495.325', 'D23.767.261.700.325'], ['C15.604.49...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]']
0
1
1
1
1
0
0
0
0
0
0
1
0
0
Transradial access for visceral endovascular interventions in morbidly obese patients: safety and feasibility.
PURPOSE: Transradial access (TRA) has been shown to lower morbidity and bleeding complications compared to transfemoral access in percutaneous coronary interventions. Morbid obesity, commonly defined as a body mass index (BMI) ?40 kg/m2, has been shown to be a risk factor for access site complications irrespective of a...
['Adult', 'Angioplasty', 'Body Mass Index', 'Catheterization, Peripheral', 'Computed Tomography Angiography', 'Databases, Factual', 'Embolization, Therapeutic', 'Feasibility Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'New York City', 'Obesity, Morbid', 'Radial Artery', 'Risk Factors', 'Time Factors', 'Treatme...
27,032,454
[['M01.060.116'], ['E02.148.050', 'E04.100.814.529.124', 'E04.502.382.124', 'E05.157.016'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E01.370....
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Anatomy [A]']
1
1
1
0
1
0
1
0
0
0
1
1
1
1
Diagnosis and treatment of primary aldosteronism.
A few simple rules can allow physicians to successfully identify many patients with arterial hypertension caused by PA among the so-called essential hypertensive patients. The hyperaldosteronism and the hypokalemia can be cured with adrenalectomy in practically all of these patients. Moreover, in a substantial proporti...
['Adrenal Cortex Neoplasms', 'Adrenalectomy', 'Adrenocortical Adenoma', 'Decision Trees', 'Diagnosis, Differential', 'Humans', 'Hyperaldosteronism', 'Hypertension', 'Hypokalemia', 'Mass Screening', 'Prevalence']
21,565,669
[['C04.588.322.078.265', 'C19.053.098.265', 'C19.053.347.500', 'C19.344.078.265'], ['E04.270.115'], ['C04.588.322.078.265.500', 'C19.053.098.265.500', 'C19.053.347.500.500', 'C19.344.078.265.500'], ['G17.162.500'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.053.800.604'], ['C14.907.489'], ['C18...
['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]']
0
1
1
0
1
0
1
0
0
0
0
0
1
0
Organ motion in pediatric high-risk neuroblastoma patients using four-dimensional computed tomography.
PURPOSE/OBJECTIVE(S): High-risk neuroblastoma (HR-NBL) requires multimodality treatment, including external beam radiation of the primary tumor site following resection. Radiotherapy planning must take into account motion of the target and adjacent normal anatomy, both of which are poorly understood in the pediatric po...
['Child', 'Child, Preschool', 'Female', 'Four-Dimensional Computed Tomography', 'Humans', 'Image Processing, Computer-Assisted', 'Infant', 'Male', 'Motion', 'Neuroblastoma', 'Organs at Risk', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy, Intensity-Modulated', 'Respiration', 'Risk Fac...
28,291,918
[['M01.060.406'], ['M01.060.406.448'], ['E01.370.350.350.810.490', 'E01.370.350.400.350', 'E01.370.350.700.700.810.490', 'E01.370.350.700.810.810.645', 'E01.370.350.825.810.810.599'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['M01.060.703'], ['G01.482'], ['C04.557.465.625.600.590.650.550', 'C04...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]']
1
1
1
0
1
0
1
0
0
0
1
1
1
0
Efficacy and safety of selenium nanoparticles administered intraperitoneally for the prevention of growth of cancer cells in the peritoneal cavity.
Peritoneal implantation of cancer cells, particularly postoperative seeding metastasis, frequently occurs in patients with primary tumors in the stomach, colon, liver, and ovary. Peritoneal carcinomatosis is associated with poor prognosis. In this work, we evaluated the prophylactic effect of intraperitoneal administra...
['Animals', 'Antineoplastic Agents', 'Carcinoma', 'Cell Proliferation', 'Male', 'Mice', 'Nanoparticles', 'Neoplasm Seeding', 'Peritoneal Neoplasms', 'Selenium']
24,727,439
[['B01.050'], ['D27.505.954.248'], ['C04.557.470.200'], ['G04.161.750', 'G07.345.249.410.750'], ['B01.050.150.900.649.313.992.635.505.500'], ['J01.637.512.600'], ['C04.697.650.830', 'C23.550.727.650.830'], ['C04.588.033.513', 'C04.588.274.780', 'C06.301.780', 'C06.844.620'], ['D01.268.185.850', 'D01.578.700']]
['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]']
0
1
1
1
0
0
1
0
0
1
0
0
0
0
Antemortem diagnosis of an apparent case of feline candidiasis.
Candidiasis in cats has always been linked with such predisposing factors as parvovirus infections and antibiotic and chemotherapeutic treatments. Moreover these cases were all diagnosed post-mortem. The clinical observations and the diagnostic procedures used in an antemortem case of probable idiopathic intestinal can...
['Animals', 'Candida albicans', 'Candidiasis', 'Cat Diseases', 'Cats', 'Enteritis', 'Feces', 'Female', 'Intestines', 'Nystatin']
3,515,195
[['B01.050'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['C01.150.703.160'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C06.405.205.462', 'C06.405.469.326'], ['A12.459'], ['A03.556.124'], ['D02.540.505.575']]
['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]']
1
1
1
1
0
0
0
0
0
0
0
0
0
0
Probing the Conformational Landscape of DNA Polymerases Using Diffusion-Based Single-Molecule FRET.
Monitoring conformational changes in DNA polymerases using single-molecule F?rster resonance energy transfer (smFRET) has provided new tools for studying fidelity-related mechanisms that promote the rejection of incorrect nucleotides before DNA synthesis. In addition to the previously known open and closed conformation...
['DNA', 'DNA Replication', 'DNA-Directed DNA Polymerase', 'Fluorescence Resonance Energy Transfer', 'Nanotechnology', 'Protein Conformation', 'Single Molecule Imaging']
27,793,286
[['D13.444.308'], ['G02.111.225', 'G05.226'], ['D08.811.913.696.445.308.300'], ['E05.196.712.516.600.676.500', 'G01.154.240.280', 'G02.111.255.280'], ['H01.603', 'J01.897.520.600'], ['G02.111.570.820.709'], ['E05.595.899', 'E05.601.555.500']]
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]']
0
0
0
1
1
0
1
1
0
1
0
0
0
0
Regulation of electrolyte and fluid metabolism in multi-stage ultra-marathoners.
The purposes of this study were (i) to determine the prevalence of exercise-associated hyponatremia (EAH) in multi-stage ultra-marathoners and (ii) to gain more insight into fluid and electrolyte regulation during a multi-stage race. Body mass, sodium concentration ([Na⁺]), potassium concentration ([K⁺]), creatinine, u...
['Adult', 'Altitude', 'Athletes', 'Humans', 'Hyperuricemia', 'Hyponatremia', 'Inappropriate ADH Syndrome', 'Male', 'Middle Aged', 'Osmolar Concentration', 'Physical Endurance', 'Potassium', 'Prevalence', 'Running', 'Severity of Illness Index', 'Sodium', 'Specific Gravity', 'Switzerland', 'Water-Electrolyte Balance']
22,638,835
[['M01.060.116'], ['G16.500.275.058', 'N06.230.058'], ['M01.072'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.449'], ['C18.452.950.620'], ['C10.228.140.617.738.320', 'C18.452.950.626', 'C19.700.490'], ['M01.060.116.630'], ['G02.640'], ['G11.427.680', 'I03.450.642.845.054.600'], ['D01.268.549.550', 'D01....
['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]']
0
1
1
1
1
0
1
0
1
0
0
1
1
1
Comparison of transvaginal surgery and methotrexate/mifepristone-combined transcervical resection in the treatment of cesarean scar pregnancy.
OBJECTIVE: To explore the safety and efficiency of transvaginal surgical treatment of cesarean scar pregnancy (CSP).PATIENTS AND METHODS: A retrospective analysis of 54 CSP patients that received treatment in our hospital from October 2011 to September 2015 was performed, dividing two groups: Group A (n=34) received tr...
['Adult', 'Blood Loss, Surgical', 'Cesarean Section', 'Chorionic Gonadotropin, beta Subunit, Human', 'Cicatrix', 'Female', 'Humans', 'Length of Stay', 'Methotrexate', 'Mifepristone', 'Operative Time', 'Pregnancy', 'Pregnancy, Ectopic', 'Retrospective Studies', 'Treatment Outcome', 'Uterine Artery Embolization']
28,682,420
[['M01.060.116'], ['C23.550.414.300', 'C23.550.505.300'], ['E04.520.252.500'], ['D06.472.699.322.326.125', 'D06.472.699.649.367.125', 'D12.644.548.726.367.125', 'D12.776.780.400.125', 'D23.101.140.325', 'D23.101.175'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['B01.050.150.900.649.313.988.400.112.400....
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]']
1
1
1
1
1
0
1
0
0
0
0
1
1
0
Diagnosis and treatment of acute cardiac tamponade by the subxiphoid approach.
Emergency cardiac surgery has been performed on 18 cases of acute cardiac tamponade whose etiologies were as follows: 11 cases of metastatic carcinoma, four cases of idiopathic pericarditis and three with other causes. In most cases, the chief complaint was dyspnea. In many cases, the cardiac silhouette of frontal ches...
['Adult', 'Aged', 'Cardiac Tamponade', 'Echocardiography', 'Electrocardiography', 'Female', 'Humans', 'Male', 'Methods', 'Middle Aged', 'Pericarditis', 'Preoperative Care', 'Tomography, X-Ray Computed', 'Xiphoid Bone']
6,670,110
[['M01.060.116'], ['M01.060.116.100'], ['C14.280.155'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['M01.060.116.630'], ['C14.280.720'], ['E02.760.795', 'E04.604.750', 'N02.421.585.795']...
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]']
1
1
1
0
1
0
0
0
0
0
0
1
1
0
The true distal posterior inferior cerebellar artery aneurysm: clinical characteristics and strategy for treatment.
OBJECTIVE: A series of aneurysms located at the 4 (th) or 5 (th) segment of the posterior inferior cerebellar artery (PICA) has not been previously reported in the literature. We report six such cases and analyze their clinical characteristics and outcomes from three different treatment strategies.MATERIAL AND METHODS:...
['Adult', 'Aged', 'Aged, 80 and over', 'Aneurysm, Ruptured', 'Arteries', 'Cerebellum', 'Cerebral Angiography', 'Embolization, Therapeutic', 'Female', 'Glasgow Outcome Scale', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Intracranial Aneurysm', 'Magnetic Resonance Imaging', 'Male', 'Mi...
20,376,738
[['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.055.185'], ['A07.015.114'], ['A08.186.211.132.810.428.200'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['E02.520.360', 'E02.926.500'], [...
['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]']
1
1
1
0
1
0
0
0
0
0
1
1
1
0
Selecting likely causal risk factors from high-throughput experiments using multivariable Mendelian randomization.
Modern high-throughput experiments provide a rich resource to investigate causal determinants of disease risk. Mendelian randomization (MR) is the use of genetic variants as instrumental variables to infer the causal effect of a specific risk factor on an outcome. Multivariable MR is an extension of the standard MR fra...
['Bayes Theorem', 'Genome-Wide Association Study', 'Humans', 'Mendelian Randomization Analysis', 'Models, Genetic', 'Risk Factors']
31,911,605
[['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.416.500'], ['E05.599.395.397'], ['...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]']
0
1
0
0
1
0
0
0
0
0
0
0
1
0
Solubilization and purification of the Ni-stimulated arginine-vasopressin binding site of rat brain membranes.
Arginine vasopressin binding sites on rat brain membranes were solubilized and purified by affinity chromatography. Membrane protein solubilized with CHAPS bound arginine vasopressin (AVP) only in the presence of divalent cations. Specific binding to the solubilized tissue was maximally stimulated by Ni2+, and markedly...
['Animals', 'Arginine Vasopressin', 'Brain Chemistry', 'Cations, Divalent', 'Chromatography, Affinity', 'Male', 'Membranes', 'Nickel', 'Rats', 'Rats, Inbred Strains', 'Receptors, Angiotensin', 'Receptors, Vasopressin', 'Solubility']
3,670,523
[['B01.050'], ['D06.472.699.631.692.781.100', 'D12.644.400.900.100', 'D12.644.456.925.100', 'D12.644.548.691.692.781.100', 'D12.776.631.650.937.100'], ['G02.111.150', 'G03.185'], ['D01.248.497.300.333'], ['E05.196.181.400.170'], ['A10.615'], ['D01.268.556.607', 'D01.268.956.625', 'D01.552.544.607'], ['B01.050.150.900.6...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Treatment of proteinuria with lercanidipine associated with renin-angiotensin axis-blocking drugs.
OBJECTIVE: Most calcium antagonists do not seem to reduce microalbuminuria or proteinuria. We have tried to assess the antiproteinuric effect of a calcium channel blocker, lercanidipine, in patients previously treated with ACE inhibitors or angiotensin receptor blockers.DESIGN AND METHODS: The study included 68 protein...
['Angiotensin II Type 1 Receptor Blockers', 'Angiotensin-Converting Enzyme Inhibitors', 'Calcium Channel Blockers', 'Dihydropyridines', 'Drug Therapy, Combination', 'Female', 'Humans', 'Male', 'Middle Aged', 'Proteinuria', 'Statistics, Nonparametric', 'Treatment Outcome']
20,199,181
[['D27.505.519.162.500'], ['D27.505.519.389.745.085'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D03.383.725.203'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C12.777.934.734', 'C13.351.968.934.734', 'C23.888.942.750'], ['E05.318.740.995', 'N0...
['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]']
0
1
1
1
1
0
0
0
0
0
0
1
1
0
Adrenal insufficiency secondary to metastatic lung carcinoma: CT aided diagnosis.
A patient with adenocarcinoma of the lung associated with clinical and laboratory evidence of adrenal insufficiency is described. Bilateral adrenal masses were identified on computed tomography and percutaneous needle biopsy confirmed metastatic adenocarcinoma. There was some clinical improvement after treatment with c...
['Adenocarcinoma', 'Adrenal Gland Neoplasms', 'Adrenal Insufficiency', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Tomography, X-Ray Computed']
6,630,647
[['C04.557.470.200.025'], ['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['C19.053.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.81...
['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
1
0
1
0
0
0
0
0
0
1
0
0
Airway mucus in recurrent airway obstruction--short-term response to environmental challenge.
Mucus accumulation and neutrophilic inflammation in the airways are hallmarks of heaves. Endoscopically visible mucus accumulations, however, have not been studied during exposure to dusty hay and allergens (ie, environmental challenge). We hypothesized that (1) heaves-affected horses have increased mucus accumulation ...
['Airway Obstruction', 'Allergens', 'Animals', 'Bronchi', 'Bronchoalveolar Lavage Fluid', 'Bronchoscopy', 'Case-Control Studies', 'Female', 'Horse Diseases', 'Horses', 'Inhalation Exposure', 'Male', 'Mucus', 'Recurrence', 'Respiratory Hypersensitivity']
14,765,737
[['C08.618.846.185'], ['D23.050.063'], ['B01.050'], ['A04.411.125'], ['E05.927.100.500'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['N06.850.460.3...
['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
1
1
1
1
1
0
0
0
0
0
0
0
1
0
Fontan type operation for complex lesions. Surgical considerations to improve survival.
Twenty-five of 49 patients who underwent a Fontan type operation had complex lesions other than tricuspid atresia with ventriculoarterial concordance. Three patients had significant subaortic stenosis. Thirty-four palliative operations, including nine Glenn shunts, were performed before the Fontan operation. Direct atr...
['Adolescent', 'Adult', 'Cardiac Catheterization', 'Cardiac Surgical Procedures', 'Child', 'Child, Preschool', 'Female', 'Heart Defects, Congenital', 'Heart Valve Prosthesis', 'Humans', 'Male', 'Palliative Care', 'Reoperation', 'Suture Techniques']
2,431,228
[['M01.060.057'], ['M01.060.116'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E04.100.376', 'E04.928.220'], ['M01.060.406'], ['M01.060.406.448'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['E07.695.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.666', 'N02.421.585.666'], ['E04.6...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]']
0
1
1
0
1
0
0
0
0
0
0
1
1
0
Morphine enhances high-affinity choline uptake in mouse striatum.
The effects of morphine (2 mg/kg-60 mg/kg) on cholinergic neuronal activity were examined by the method of high-affinity, Na+-dependent [3H]choline uptake into synaptosomes isolated from mouse corpus striatum. Acute administration of analgesic doses of morphine (10 mg/kg, 20 mg/kg) significantly stimulated choline upta...
['Amantadine', 'Animals', 'Behavior, Animal', 'Choline', 'Corpus Striatum', 'Dihydroxyphenylalanine', 'Dopamine', 'Haloperidol', 'Male', 'Mice', 'Morphine', 'Sodium']
6,815,665
[['D02.455.426.100.050.035'], ['B01.050'], ['F01.145.113'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['A08.186.211.200.885.287.249.487'], ['D02.092.311.200', 'D02.455.426.559.389.657.166.175.200', 'D12.125.072.050.685.400', 'D12.125.072.050.875.130'], ['D02.092.211.215.4...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]']
1
1
0
1
0
1
0
0
0
0
0
0
0
0
Mechanistic modeling of sulfur-deprived photosynthesis and hydrogen production in suspensions of Chlamydomonas reinhardtii.
The ability of unicellular green algal species such as Chlamydomonas reinhardtii to produce hydrogen gas via iron-hydrogenase is well known. However, the oxygen-sensitive hydrogenase is closely linked to the photosynthetic chain in such a way that hydrogen and oxygen production need to be separated temporally for susta...
['Chlamydomonas reinhardtii', 'Hydrogen', 'Models, Theoretical', 'Photosynthesis', 'Sulfur', 'Suspensions']
24,026,984
[['B01.650.940.150.385.650'], ['D01.268.406', 'D01.362.340'], ['E05.599'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.568'], ['D01.268.185.900'], ['D20.280.810', 'D26.255.165.810']]
['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]']
0
1
0
1
1
0
1
0
0
0
0
0
0
0
Photochemical reduction of hexavalent chromium in glycerol-containing solutions.
Hexavalent chromium [Cr(VI)] in the form of potassium dichromate was photochemically reduced to trivalent chromium [Cr(III)] in aqueous solutions containing glycerol. This reaction occurred rapidly during irradiation with either unfiltered sunlight or a UVA-emitting light source. Photochemical reduction of Cr(VI) was p...
['Carcinogens, Environmental', 'Chromium', 'Glycerol', 'Hazardous Waste', 'Oxidation-Reduction', 'Photochemistry', 'Solutions']
11,843,525
[['D27.888.569.100.125'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D02.033.800.875.500', 'D09.853.875.500'], ['D20.944.380', 'D27.888.426.500', 'N06.850.460.710.380'], ['G02.700', 'G03.295.531'], ['H01.181.529.711'], ['D26.776']]
['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]']
0
0
0
1
0
0
1
1
0
0
0
0
1
0
Nuclear factor-kappa B and apoptosis inducing factor activation by doxorubicin analog WP744 in SH-SY5Y neuroblastoma cells.
BACKGROUND: Neuroblastoma (NB) is one of the most common extracranial tumors in children. The chemotherapeutic doxorubicin (Dox) remains a mainstay for treatment. However, the emergence of drug resistance seriously limits treatment efficacy. Numerous Dox analogues have been designed to more potently kill drug naive as ...
['Anthracyclines', 'Apoptosis', 'Apoptosis Inducing Factor', 'Biological Transport', 'Caspases', 'Cell Death', 'Cell Line, Tumor', 'Doxorubicin', 'Enzyme Activation', 'Flavoproteins', 'Humans', 'Membrane Proteins', 'NF-kappa B', 'Neuroblastoma', 'Tumor Suppressor Protein p53']
15,555,623
[['D02.455.426.559.847.562.050', 'D04.615.562.050', 'D09.408.051.059'], ['G04.146.954.035'], ['D08.811.682.608.047', 'D12.644.360.075.311', 'D12.776.157.687.063', 'D12.776.331.161', 'D12.776.476.075.311', 'D12.776.660.720.063'], ['G03.143'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.07...
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]']
1
1
1
1
0
0
1
0
0
0
0
0
0
0
Polyamines induce blood-brain barrier disruption and edema formation in the rat.
Polyamines (PA) are derived from ornithine by the enzyme ornithine decarboxylase (ODC), which is activated very rapidly as acute and delayed responses to brain ischemia and trauma. Polyamines play a role in the disruption of the blood-brain barrier (BBB) in different pathological states. This study examined the effect ...
['Analysis of Variance', 'Animals', 'Blood-Brain Barrier', 'Brain Edema', 'Dronabinol', 'Injections, Intraventricular', 'Male', 'Neuroprotective Agents', 'Polyamines', 'Rats', 'Specific Gravity']
8,983,332
[['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A07.035', 'A08.186.211.035'], ['C10.228.140.187'], ['D02.455.849.090.810'], ['E02.319.267.530.550'], ['D27.505.696.706.548', 'D27.505.954.427.575'], ['D02.092.782'], ['B01.050.150.900.649.313.992.635.505.700'], ['G02.819']]
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]']
1
1
1
1
1
0
1
0
0
0
0
0
1
0
[Bladder tumors discovered during pregnancy (apropos of 3 cases)].
The authors present 3 cases of vesical tumours discovered during pregnancy, which, according to literature, very rarely happens. These women from the low socio-economic strata had many children and were seen at a late stage when diagnosis of vesical tumours is easily distinguished from haematuria, recurrent cysts and h...
['Adult', 'Carcinoma, Squamous Cell', 'Female', 'Fetal Growth Retardation', 'Hematuria', 'Humans', 'Infant, Newborn', 'Kidney Failure, Chronic', 'Male', 'Pregnancy', 'Pregnancy Complications, Neoplastic', 'Rhabdomyosarcoma', 'Senegal', 'Socioeconomic Factors', 'Urinary Bladder Neoplasms']
2,135,796
[['M01.060.116'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C13.703.277.370', 'C16.300.390', 'C23.550.393.450'], ['C12.777.934.442', 'C13.351.968.934.442', 'C23.550.414.849'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['G08....
['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]']
0
1
1
0
0
0
1
0
1
0
0
1
1
1
Fog1 is required for cardiac looping in zebrafish.
To further our understanding of FOG gene function during cardiac development, we utilized zebrafish to examine FOG's role in the early steps of heart morphogenesis. We identified fragments of three fog genes in the zebrafish genomic database and isolated full-length coding sequences for each of these genes by using a c...
['Animals', 'Base Sequence', 'Brain', 'Conserved Sequence', 'GATA4 Transcription Factor', 'Heart', 'Mice', 'Molecular Sequence Data', 'Mutation', 'Nuclear Proteins', 'Protein Isoforms', 'Sequence Homology', 'Transcription Factors', 'Transfection', 'Zebrafish', 'Zebrafish Proteins']
16,316,643
[['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A08.186.211'], ['G02.111.570.580'], ['D12.776.260.257.400', 'D12.776.930.314.400'], ['A07.541'], ['B01.050.150.900.649.313.992.635.505.500'], ['L01.453.245.667'], ['G05.365.590'], ['D12.776.660'], ['D12.776.800'], ['G02.111.810', 'G05.810'], ['D...
['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
0
1
1
0
1
0
0
0
1
0
0
0
Randomized trial of bone marrow versus lenograstim-primed blood cell allogeneic transplantation in patients with early-stage leukemia: a report from the Soci?t? Fran?aise de Greffe de Moelle.
PURPOSE: To compare hematologic recovery in patients receiving allogeneic blood cell transplantation (BCT) with those receiving allogeneic bone marrow transplantation (BMT).PATIENTS AND METHODS: One hundred eleven patients with leukemia in the early stages and with HLA-matched sibling donors were randomized in this stu...
['Acute Disease', 'Adjuvants, Immunologic', 'Adult', 'Bone Marrow Transplantation', 'Female', 'Granulocyte Colony-Stimulating Factor', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Lenograstim', 'Leukemia', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Leukemia, Myeloid', 'Male', 'Precursor Cell Lymphobl...
10,653,869
[['C23.550.291.125'], ['D27.505.696.477.067'], ['M01.060.116'], ['E02.095.147.725.040', 'E04.936.580.040'], ['D12.644.276.374.410.240.350', 'D12.776.395.240.200', 'D12.776.467.374.410.240.350', 'D23.529.374.410.240.350'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'...
['Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]']
0
1
1
1
1
0
0
0
0
0
0
1
1
0
Bacteriophage P4282, a parasite of Ralstonia solanacearum, encodes a bacteriolytic protein important for lytic infection of its host.
To enhance bacterial wilt resistance in tobacco expressing a foreign protein, we isolated the bacteriolytic gene from a bacteriophage that infects Ralstonia solanacearum. The bacteriolytic protein of phage P4282 isolated in Tochigi Prefecture was purified from a lysate of R. solanacearum M4S cells infected with the pha...
['Bacteriolysis', 'Bacteriophages', 'Burkholderia', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Molecular Sequence Data', 'Open Reading Frames', 'Viral Proteins']
11,370,877
[['G06.099.115'], ['B04.123'], ['B03.660.075.090.688.100'], ['E05.196.401.402', 'E05.301.300.319'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['L01.453.245.667'], ['G05.360.335.760.640', 'G05.360.340.024.340.137.650'], ['D12.776.964']]
['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]']
0
1
0
1
1
0
1
0
0
0
1
0
0
0
Recurrent Primary Cardiac Sarcoma Managed With Radical Cardiac Resection and Pneumonectomy.
Primary cardiac tumors are extremely rare. Although complete surgical resection of malignant primary cardiac tumors results in an improved survival compared with no intervention, the overall prognosis is generally poor, with treatable recurrent primary cardiac sarcomas being extremely rare. We report a patient with a r...
['Cardiac Surgical Procedures', 'Heart Neoplasms', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Pneumonectomy', 'Sarcoma']
26,234,853
[['E04.100.376', 'E04.928.220'], ['C04.588.894.309', 'C14.280.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['E04.620', 'E04.928.600.600'], ['C04.557.450.795']]
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]']
0
1
1
0
1
0
0
0
0
0
0
1
0
0
Routine testing shows benefits in urban hospital. Atlanta effort finds more HIV-positives.
Following up on its 1993 recommendations that hospitals and clinics in areas with high rates of HIV prevalence offer routine HIV testing to patients, the Centers for Disease Control and Prevention conducted a recent study of such a practice. From March 20 to Sept. 1, 2000, clinicians in Atlanta were encouraged to recom...
['AIDS Serodiagnosis', 'Diagnostic Tests, Routine', 'Education, Continuing', 'Georgia', 'HIV Infections', 'HIV Seroprevalence', 'Hospitals, Urban', 'Humans']
11,590,935
[['E01.370.225.812.735.060', 'E01.370.225.875.408.500', 'E05.200.812.735.060', 'E05.200.875.408.500', 'E05.478.594.760.060'], ['E01.370.395'], ['I02.358.212'], ['Z01.107.567.875.075.250', 'Z01.107.567.875.750.370'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.40...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]']
0
1
1
0
1
0
0
0
1
0
0
0
1
1
Iron deficiency, Helicobacter infection and gastritis.
Despite elegant regulatory mechanisms, iron deficiency anemia (IDA) remains one of the most common nutritional deficiencies of mankind. Iron deficiency is the result of an interplay between increased host requirements, limited external supply, and increased blood loss. When related to increased physiologic needs associ...
['Adult', 'Anemia, Iron-Deficiency', 'Autoimmune Diseases', 'Female', 'Gastritis', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Iron', 'Male', 'Middle Aged']
19,907,146
[['M01.060.116'], ['C15.378.071.196.300', 'C18.452.565.100'], ['C20.111'], ['C06.405.205.697', 'C06.405.748.398'], ['C01.150.252.400.466'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['M01.060.116.630']]
['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]']
0
1
1
1
0
0
0
0
0
0
0
1
0
0
The extent, nature, and pathogenic consequences of helminth polyparasitism in humans: A meta-analysis.
BACKGROUND: Individual helminth infections are ubiquitous in the tropics; geographical overlaps in endemicity and epidemiological reports suggest areas endemic for multiple helminthiases are also burdened with high prevalences of intestinal protozoan infections, malaria, tuberculosis (TB), and human immunodeficiency vi...
['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Coinfection', 'Female', 'HIV Infections', 'Helminthiasis', 'Humans', 'Infant', 'Infant, Newborn', 'Malaria', 'Male', 'Middle Aged', 'Prevalence', 'Protozoan Infections', 'Tropical Climate', 'Tuberculosis', 'Young Adult']
31,211,774
[['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['C01.218'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['C01.610.335'], ['B01.050.150.900.649.313.988.400.112.400.400']...
['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]']
0
1
1
0
1
0
1
0
0
0
0
1
1
0
Serum cytokine and chemokine changes during Toscana virus meningitis.
Toscana virus is an important arbovirus causing meningitis and meningoencephalitis in countries around the Mediterranean Sea. While the clinical syndrome and laboratory diagnostic procedures have been well described, less is known about the immune response in Toscana virus meningitis and a possible use of cytokine and ...
['Adolescent', 'Adult', 'Aged', 'Cytokines', 'Female', 'Humans', 'Italy', 'Longitudinal Studies', 'Male', 'Meningitis, Viral', 'Middle Aged', 'Phlebotomus Fever', 'Sandfly fever Naples virus', 'Serum', 'Young Adult']
30,976,912
[['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['C01.207.245.500', 'C01.925.182.550', 'C10.228.228....
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]']
1
1
1
1
1
0
0
0
0
0
0
1
1
1
Perineurial cell differentiation in benign tumors and tumorlike proliferation of peripheral nerves.
An unusual, benign, spindle cell peripheral nerve sheath tumor (PNST) is reported that on ultrastructural examination was composed only of perineurial cells. The neoplastic cells showed positive immunoreactivity for S-100 protein and negative immunoreactivity for epithelial membrane antigen; this is not the expected im...
['Adult', 'Cell Division', 'Female', 'Follow-Up Studies', 'Foot Diseases', 'Humans', 'Peripheral Nervous System Neoplasms']
8,266,591
[['M01.060.116'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C05.360', 'C17.800.321'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.614.596', 'C10.551.775', 'C10.668.829.725']]
['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]']
0
1
1
0
1
0
1
0
0
0
0
1
1
0
The Neural Responses to Social Cooperation in Gain and Loss Context.
Cooperation is pervasive and constitutes the core behavioral principle of human social life. Previous studies have revealed that mutual cooperation was reliably correlated with two reward-related brain regions, the ventral striatum and the orbitofrontal cortex. Using functional magnetic resonance imaging (fMRI), this s...
['Adult', 'Brain', 'Cooperative Behavior', 'Female', 'Humans', 'Interpersonal Relations', 'Magnetic Resonance Imaging', 'Neuropsychological Tests', 'Prefrontal Cortex', 'Reward', 'Social Behavior']
27,494,142
[['M01.060.116'], ['A08.186.211'], ['F01.145.813.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['E01.370.350.825.500'], ['F04.711.513'], ['A08.186.211.200.885.287.500.270.700'], ['F02.463.425.770.836'], ['F01.145.813']]
['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
0
0
1
1
0
0
0
0
0
1
0
0
A comparative immunohistochemical study on striatal Met-enkephalin expression in Alzheimer's disease and in progressive supranuclear palsy.
Using a sensitive immunoperoxidase technique we examined Met-enkephalin (MEnk) expression in the striatum and globus pallidus external segment (GPe) from patients with Alzheimer's disease (AD) and with progressive supranuclear palsy (PSP). In AD patients strong MEnk-like immunoreactivity was persistent in the striatum ...
['Alzheimer Disease', 'Brain', 'Caudate Nucleus', 'Enkephalin, Methionine', 'Globus Pallidus', 'Humans', 'Immunoenzyme Techniques', 'Organ Specificity', 'Putamen', 'Supranuclear Palsy, Progressive']
2,085,095
[['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['A08.186.211'], ['A08.186.211.200.885.287.249.487.550.184'], ['D12.644.400.575.281.381', 'D12.776.631.650.575.281.381'], ['A08.186.211.200.885.287.249.487.397'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05....
['Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]']
1
1
1
1
1
1
1
0
0
0
0
0
0
0
[Yeast-based production, purification and bioactivity assay of rainbow trout LECT2].
Leukocyte cell-derived chemotaxin 2 (LECT2) is a secretory cytokine that functions in many physiological and pathological processes. We used a Pichia pastoris expression system for the recombinant expression of rainbow trout LECT2. The recombinant LECT2 was purified by UNOsphere S Cation exchange and size-exclusion chr...
['Animals', 'Blotting, Western', 'Cathepsin D', 'Chromatography, Gel', 'Chromatography, Ion Exchange', 'Cytotoxicity, Immunologic', 'Escherichia coli', 'Fish Proteins', 'Gene Expression', 'Head Kidney', 'Intercellular Signaling Peptides and Proteins', 'Macrophage Activation', 'Macrophages', 'Oncorhynchus mykiss', 'Pich...
23,389,976
[['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D08.811.277.656.074.500.180', 'D08.811.277.656.224.187', 'D08.811.277.656.300.048.180'], ['E05.196.181.400.250'], ['E05.196.181.400.383'], ['G12.287'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.10...
['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Standardization of allergenic extracts of Aspergillus fumigatus. Liberation of IgE-binding components during cultivation.
During cultivation of Aspergillus fumigatus a rapid liberation of IgE-binding components was found reaching maximum values during the logarithmic phase of growth (phase I). After a fall in IgE-binding titers during phase II, appearance of additional IgE-binding components was noted during the period of lysis of the mic...
['Allergens', 'Antigens, Fungal', 'Aspergillus fumigatus', 'Binding Sites, Antibody', 'Culture Techniques', 'Epitopes', 'Hydrogen-Ion Concentration', 'Immunoelectrophoresis', 'Immunoglobulin E', 'Tissue Extracts']
2,578,438
[['D23.050.063'], ['D23.050.202'], ['B01.300.381.081.295'], ['G02.111.570.060.425.079', 'G02.111.570.120.408', 'G12.122.232', 'G12.125'], ['E05.481.500'], ['D23.050.550'], ['G02.300'], ['E01.370.225.812.735.645.350.350', 'E05.196.401.568', 'E05.200.812.735.645.350.350', 'E05.301.300.568', 'E05.478.594.760.645.350.350',...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
0
1
1
0
1
0
0
0
0
0
0
0
A cyclometalated trinuclear Ir(iii)/Pt(ii) complex as a luminescent probe for histidine-rich proteins.
Organometallic complexes have important application in the field of protein staining, with potential for use in proteomic analysis. The rational synthesis of a trinuclear luminescent organometallic complex with two platinum(ii) centres appended to the cyclometalated ligand of the iridium(iii) centre is reported here. T...
['Coordination Complexes', 'Imidazoles', 'Iridium', 'Luminescence', 'Luminescent Agents', 'Models, Molecular', 'Proteins', 'Staining and Labeling']
31,967,143
[['D01.234', 'D02.257'], ['D03.383.129.308'], ['D01.268.556.401', 'D01.268.956.280', 'D01.552.544.401'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.750.250.650.665', 'G01.750.770.578.665'], ['D27.720.470.410.505'], ['E05.599.595'], ['D12.776'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.50...
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
0
0
1
1
0
1
0
0
0
0
0
0
0
Correlative Microscopy for Localization of Proteins In Situ: Pre-embedding Immuno-Electron Microscopy Using FluoroNanogold, Gold Enhancement, and Low-Temperature Resin.
Immuno-electron microscopy (immuno-EM) is a technique that has been used widely to determine subcellular localization of proteins. Different approaches are available for immuno-EM: pre-embedding method, post-embedding, and cryosectioning (Tokuyasu "style"). Here we describe a pre-embedding technique that allows the lab...
['Acrylic Resins', 'Animals', 'Antibodies', 'Cell Line', 'Cold Temperature', 'Connexin 43', 'Epithelial Cells', 'Gap Junctions', 'Gene Expression', 'Glutaral', 'Kidney', 'Metal Nanoparticles', 'Microscopy, Fluorescence', 'Microscopy, Immunoelectron', 'Rats', 'Stilbamidines', 'Tissue Embedding', 'Tissue Fixation']
26,160,575
[['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['A11.251.210'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.7...
['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
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1
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