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Microbial transformations of steroids--III. Transformation of progesterone by Sepedonium ampullosporum. | The 16 alpha-steroid hydroxylating fungus Sepedonium ampullosporum (CMI strain 203 033) transformed progesterone into 16 alpha-hydroxyprogesterone and four other major metabolites which have not been reported previously for this organism, 6 beta-hydroxyprogesterone, 17 alpha-hydroxyprogesterone, 16 alpha-hydroxyandrost... | ['Biotransformation', 'Chromatography, High Pressure Liquid', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Mitosporic Fungi', 'Progesterone', 'Time Factors'] | 2,761,271 | [['G03.171', 'G03.787.225', 'G07.690.725.225'], ['E05.196.181.400.300'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519'], ['B01.300.381'], ['D04.210.500.745.745.654.829', 'D06.472.334.734.623', 'D06.472.334.851.687.750'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pharmacological actions of WEB 2086, a new specific antagonist of platelet activating factor. | WEB 2086, a thieno-triazolodiazepine, is a potent and specific antagonist of platelet activating factor (PAF) in vitro and in vivo. This compound inhibits PAF-induced human platelet and neutrophil aggregation in vitro (IC50 = 0.17 and 0.36 microM, respectively) but has little or no effect on the action of other platele... | ['Animals', 'Anticonvulsants', 'Azepines', 'Capillary Permeability', 'Chemical Phenomena', 'Chemistry', 'Guinea Pigs', 'Humans', 'Hypnotics and Sedatives', 'Indium', 'Neutrophils', 'Platelet Activating Factor', 'Platelet Aggregation', 'Skin', 'Triazines', 'Triazoles'] | 3,598,913 | [['B01.050'], ['D27.505.954.427.080'], ['D03.383.066'], ['G03.143.330', 'G09.330.165'], ['G02'], ['H01.181'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.350', 'D27.505.954.427.210.350'], ['D01.268.556.381', 'D01.552.544.381'], ['A11.118.637.415.583', 'A11.627... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The use of human acellular dermal matrix for chest wall reconstruction. | BACKGROUND: Reconstruction of chest wall defects has evolved, but challenges remain. This is particularly true when defects are large or contamination is present. Although numerous materials are available for reconstruction, acellular dermal matrix has the advantage of becoming vascularized and incorporated autologousl... | ['Adolescent', 'Adult', 'Aged', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Reconstructive Surgical Procedures', 'Retrospective Studies', 'Skin, Artificial', 'Thoracic Neoplasms', 'Thoracic Wall', 'Thoracotomy', 'Treatment Outcome', 'Wound Healing', 'Young Adult'] | 21,095,314 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.680'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Laparoscopic removal of renal cysts in patients with ADPKD as an alternative method of treatment and patient preparation for kidney transplantation: preliminary results. | BACKGROUND: The most frequent genetic disease of the kidneys occurring in 1 of 1000 inhabitants is autosomal-dominant polycystic kidney disease (ADPKD). Growing renal cysts compress the kidney resulting in damage to parenchyma and functional disorders. Around 10% of these patients are dialyzed due to terminal renal ins... | ['Female', 'Humans', 'Kidney Diseases, Cystic', 'Kidney Transplantation', 'Laparoscopy', 'Male', 'Middle Aged', 'Polycystic Kidney Diseases', 'Polycystic Kidney, Autosomal Dominant', 'Preoperative Care', 'Retrospective Studies'] | 16,504,654 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.403', 'C13.351.968.419.403'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['C12.777.419.403.875', 'C13.351.968.419.403.875', 'C16.131.077.717', 'C16.320.184.625'], ['C12.777.419.40... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of the primary structure of the functional domains of human and porcine von Willebrand factor that mediate platelet adhesion. | Porcine von Willebrand factor (vWF) directly aggregates human platelets in vitro indicating a conformational difference between the human and porcine molecules. We amplified and directly sequenced 1242 nucleotides of porcine vWF cDNA that encodes functional domains which mediate the binding of vWF to platelets and sube... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Humans', 'Lung', 'Macromolecular Substances', 'Molecular Sequence Data', 'Oligodeoxyribonucleotides', 'Platelet Adhesiveness', 'Polymerase Chain Reaction', 'RNA', 'RNA-Directed DNA Polymerase', 'Sequence Homology, Nucleic Acid', 'Swine', 'von Willebrand Factor'] | 1,370,885 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['D05'], ['L01.453.245.667'], ['D13.695.578.424.450'], ['G09.188.390.600.500', 'G09.188.670'], ['E05.393.620.500'], ['D13.444.735'], ['D08.81... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Results of Walking in Faith: A Faith-Based Physical Activity Program for Clergy. | Clergy are disproportionately affected by obesity and chronic disease. Physical activity (PA) offers a viable option for addressing the health of clergy. The purpose of this study was to evaluate the effectiveness of a culturally tailored PA program for clergy. Clergy (N = 44) were randomly assigned to an intervention ... | ['Chronic Disease', 'Clergy', 'Female', 'Health Promotion', 'Humans', 'Male', 'Middle Aged', 'Obesity', 'Program Evaluation', 'Self Efficacy', 'Walking'] | 27,178,321 | [['C23.550.291.500'], ['M01.526.799.500'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650']... | ['Diseases [C]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Influence of sarcoplasmic reticulum calcium loading on mechanical and relaxation restitution. | Mechanical and relaxation restitution represent the restoration of contractile force and relaxation, respectively, in premature beats having progressively longer extrasystolic intervals (ESI); these phenomena are related to intracellular activator Ca(2+) by poorly defined mechanisms. We tested the hypothesis that the l... | ['Animals', 'Biomechanical Phenomena', 'Blood Pressure', 'Calcium', 'Calcium-Binding Proteins', 'Heart Rate', 'Mice', 'Mice, Knockout', 'Myocardial Contraction', 'Ryanodine', 'Sarcoplasmic Reticulum'] | 10,710,365 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.125'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Photon beam characterization and modelling for Monte Carlo treatment planning. | Photon beams of 4, 6 and 15 MV from Varian Clinac 2100C and 2300C/D accelerators were simulated using the EGS4/BEAM code system. The accelerators were modelled as a combination of component modules (CMs) consisting of a target, primary collimator, exit window, flattening filter, monitor chamber, secondary collimator, r... | ['Models, Theoretical', 'Monte Carlo Method', 'Particle Accelerators', 'Phantoms, Imaging', 'Photons', 'Radiotherapy Planning, Computer-Assisted', 'Software'] | 10,701,512 | [['E05.599'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['E07.710.680'], ['E07.671'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782'], ['E02.950.825', 'L01.313.500.750.100.710.600.608'], ['L01.224.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Macrophages from rat livers with micronodular and macronodular cirrhosis differ with respect to mediator release and DNA-synthesis. | BACKGROUND/AIMS: Liver macrophages play an essential role in necro-inflammatory liver damage which leads to fibrosis and cirrhosis. The aim of the present study was to compare the mediator release and the DNA synthesis of macrophages at an early and at a later stage of liver cirrhosis induced by thioacetamide.METHODS: ... | ['Animals', 'Cytokines', 'DNA', 'Female', 'Interferon-gamma', 'Interleukin-6', 'Lipopolysaccharides', 'Liver', 'Liver Cirrhosis, Experimental', 'Macrophages', 'Nitric Oxide', 'Rats', 'Rats, Wistar', 'Superoxides', 'Tumor Necrosis Factor-alpha'] | 9,186,840 | [['B01.050'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D13.444.308'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615.350'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.37... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Infertility among human immunodeficiency virus-positive women: incidence and treatment dilemmas. | The increasing demand for fertility advice among human immunodeficiency virus (HIV)-positive women under our care led us to review the incidence of infertility and the ethical problems associated with its management. All HIV-positive women who attended the HIV outpatients clinic from October 1990 to the end of January ... | ['Acquired Immunodeficiency Syndrome', 'Adolescent', 'Adult', 'African Americans', 'Ethics, Medical', 'European Continental Ancestry Group', 'Female', 'Fertilization in Vitro', 'HIV Infections', 'Humans', 'Infertility, Female', 'Male', 'Parity', 'Pregnancy', 'Sexual Behavior', 'Substance Abuse, Intravenous'] | 9,021,393 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.057'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['M01.686.508.400'... | ['Diseases [C]', 'Named Groups [M]', 'Humanities [K]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Promoter hypomethylation contributes to the expression of MUC3A in cancer cells. | MUC3A is a membrane-bound glycoprotein that is aberrantly expressed in carcinomas and is a risk factor for a poor prognosis. However, the exact mechanism of MUC3A expression has yet to be clarified. Here, we provide the first evidence that MUC3A gene expression is controlled by the CpG methylation status of the proxima... | ["5' Flanking Region", 'Azacitidine', 'Carcinoma', 'Cell Line, Tumor', 'DNA Methylation', 'Decitabine', 'Gene Expression', 'Gene Expression Regulation, Neoplastic', 'Gene Silencing', 'Humans', 'Hydroxamic Acids', 'Mucin-3', 'RNA, Messenger'] | 20,510,874 | [['G05.360.340.024.220.282', 'G05.360.340.024.340.137.295'], ['D02.145.150', 'D03.383.742.680.245.217', 'D13.570.685.245.217', 'D13.570.800.286.300'], ['C04.557.470.200'], ['A11.251.210.190', 'A11.251.860.180'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D02.145.150.500', 'D03.383.742.680.2... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Evaluation of tympano-ossicular allografts in reconstructive surgery of the middle ear]. | The results of 47 patients operated in I Clinic of Laryngology in Katowice was shown. They divided into two groups, depending on kind of allograft and type of reconstructive operation. In first group (25 patients) a total tympano-ossicular allograft had been applied. In second group (22 patients) implantation of eardru... | ['Ear Ossicles', 'Ear, Middle', 'Hearing Disorders', 'Hearing Tests', 'Humans', 'Transplantation, Homologous', 'Treatment Outcome', 'Tympanic Membrane'] | 8,028,908 | [['A09.246.397.247'], ['A09.246.397'], ['C09.218.458', 'C10.597.751.418', 'C23.888.592.763.393'], ['E01.370.382.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.936.864'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['A09.246.272.702']] | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Fiber-enriched double-setting calcium phosphate bone cement. | Calcium phosphate bone cements are useful in orthopedics and traumatology, their main advantages being their biocompatibility and bioactivity, which render bone tissue osteoconductive, providing in situ hardening and easy handling. However, their low mechanical strength, which, in the best of cases, is equal to the tra... | ['Biocompatible Materials', 'Body Fluids', 'Bone Cements', 'Calcium Phosphates', 'Carbon', 'Compressive Strength', 'Materials Testing', 'Microscopy, Electron, Scanning', 'Nylons', 'Polypropylenes', 'Tensile Strength'] | 12,734,819 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['A12.207'], ['D05.750.716.822.300', 'D25.720.716.822.300', 'D27.720.102.158', 'J01.637.051.720.716.822.300'], ['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['D01.268.150'], ['G01.374.180'], ['E05.570'], ['E01.370.350.515.402.541', 'E05.59... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A mechanical approach to the longitudinal dispersion of gas flowing in human airways. | The aim of this work is to contribute to elucidating the mechanism underlying gas mixing in the human pulmonary airways. For this purpose, a particular attempt is made to analyse the fluid mechanical aspects of gaseous dispersion using bolus response methods. The experiments were performed on five normal subjects by in... | ['Airway Resistance', 'Biomechanical Phenomena', 'Humans', 'Models, Biological', 'Pulmonary Gas Exchange', 'Pulmonary Ventilation'] | 4,008,510 | [['E01.370.386.700.050', 'G09.772.060'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['E01.370.386.700.650', 'G03.143.775.602', 'G09.772.705.760.602'], ['E01.370.386.700.660', 'G09.772.650']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of increasing doses of beta-agonists on airway and parenchymal hysteresis. | We examined the effects of a deep inhalation on airway caliber before and after increasing doses of a beta-agonist in eight subjects, including one former and two current but mild asthmatics. With bronchodilation the increase in maximal flow on the partial flow-volume curve (P), initiated from functional residual capac... | ['Administration, Inhalation', 'Adult', 'Albuterol', 'Asthma', 'Bronchi', 'Female', 'Humans', 'Lung Volume Measurements', 'Male', 'Maximal Expiratory Flow-Volume Curves', 'Middle Aged', 'Pulmonary Ventilation'] | 2,312,479 | [['E02.319.267.050'], ['M01.060.116'], ['D02.033.100.291.057', 'D02.092.063.291.057', 'D02.092.471.683.061'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['A04.411.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.700.485'], ['E01.370.386.700.660.225.505', 'G09.772.650.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Beta-2-microglobulin levels in the cerebrospinal fluid of normal dogs and dogs with neurological disease. | BACKGROUND: Cerebrospinal fluid (CSF) analysis is the basis for establishing a diagnosis of central nervous system (CNS) inflammation. However, the information provided by routine CSF analysis is limited. Determination of CSF beta-2-microglobulin (beta2m) concentration has been used diagnostically in humans to identify... | ['Animals', 'Dog Diseases', 'Dogs', 'Encephalitis', 'Meningitis', 'Myelitis', 'Reference Values', 'beta 2-Microglobulin'] | 17,523,091 | [['B01.050'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['C10.228.140.430'], ['C10.228.614'], ['C01.207.618', 'C10.228.228.618', 'C10.228.854.525'], ['E05.978.810'], ['D12.776.124.790.223.100', 'D12.776.377.715.182.100', 'D12.776.395.550.489.100', 'D12.776.543.550.439.100', 'D23.050.301.500.100.175', 'D... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Validity of exposure data derived from a structured questionnaire. | It is often convenient to obtain occupational exposure information directly from employees. However, there is little published evidence on the validity of such data. Information from a short, pre-coded, structured questionnaire, administered by non-expert interviewers, was compared with information derived from managem... | ['Age Factors', 'Chemical Industry', 'England', 'Humans', 'Ink', 'Occupational Exposure', 'Plastics', 'Printing', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Sex Factors', 'Surveys and Questionnaires'] | 1,570,822 | [['N05.715.350.075', 'N06.850.490.250'], ['J01.576.655.437'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.637.500'], ['N06.850.460.350.600'], ['D05.750.716', 'D25.720.716', 'J01.637.051.720.716'], ['L01.737.787'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445... | ['Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
Shotgun diagnosis: "it ought to be something else". | The problems encountered by the surgeon, the radiologist, and the pathologist in the interpretation of radiopaque fragments within tissue are illustrated by a case report. Deformation, particularly flattening, of round pellets should be recognized as a gross radiographic pitfall. The potential and actual external and i... | ['Adolescent', 'Femur', 'Forensic Medicine', 'Humans', 'Male', 'Radiography', 'Wounds, Gunshot'] | 7,097,211 | [['M01.060.057'], ['A02.835.232.043.150'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['C26.986.900']] | ['Named Groups [M]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
Quantitation of hepatitis C virus using an in-house real-time reverse transcriptase polymerase chain reaction in plasma samples. | Even with the most advanced 3rd-generation assays, the serologic window period of hepatitis C virus (HCV) is approximately 74 days. HCV RNA detection would reduce the risk of transmission during this period. Furthermore, quantitation of HCV RNA is necessary for proper planning of treatment, monitoring disease progressi... | ['HIV Antibodies', 'Hepacivirus', 'Hepatitis B Antigens', 'Hepatitis C Antibodies', 'Humans', 'Plasma', 'RNA, Viral', 'Reproducibility of Results', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sensitivity and Specificity', 'Viral Load'] | 18,486,403 | [['D12.776.124.486.485.114.254.150.440', 'D12.776.124.790.651.114.254.150.440', 'D12.776.377.715.548.114.254.150.440'], ['B04.450.380', 'B04.820.578.344.475'], ['D23.050.327.495.500'], ['D12.776.124.486.485.114.254.450.510', 'D12.776.124.790.651.114.254.450.510', 'D12.776.377.715.548.114.254.450.510'], ['B01.050.150.90... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Distribution of genital human papillomavirus (HPV) genotypes in Croatian women with cervical intraepithelial neoplasia (CIN)--a pilot study. | Genital infection with high-risk human papillomavirus (HR HPV) associates with increased risk of developing precancerous lesions, such as cervical intraepithelial neoplasia (CIN). The objective of this pilot study conducted in north-east Croatia was to determine the prevalence of HPV genital infection in women with abn... | ['Adult', 'Alphapapillomavirus', 'Cervical Intraepithelial Neoplasia', 'Genotype', 'Humans', 'Pilot Projects', 'Young Adult'] | 24,611,331 | [['M01.060.116'], ['B04.280.210.655.050', 'B04.613.204.655.050'], ['C04.557.470.200.240.250'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['M01.060.116.815']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Estimating the cost of vaccine development against epidemic infectious diseases: a cost minimisation study. | BACKGROUND: The Coalition for Epidemic Preparedness Innovations was established in 2016, to develop vaccines that can contribute to preparedness for outbreaks of epidemic infectious diseases. Evidence on vaccine development costs for such diseases is scarce. Our goal was to estimate the minimum cost for achieving vacci... | ['Communicable Disease Control', 'Costs and Cost Analysis', 'Drug Development', 'Epidemics', 'Humans', 'Vaccines'] | 30,342,925 | [['N06.850.780.200'], ['N03.219.151'], ['E05.290', 'H01.158.703.007.338', 'H01.181.466.338'], ['N06.850.290.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.215.894']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Regioselectivity in the glycosylation of 5-(3-chlorobenzo[b]thien-2-yl)-4H-1,2,4-triazole-3-thiol. | The glycosylation of 5-(3-chlorobenzo[b]thien-2-yl)-4H-1,2,4-triazole-3-thiol (1) and its 3-benzylsulfanyl and 3-methylsulfanyl derivatives with different glycosyl halides 2-4 has been studied in presence of base. The S-glycosides 5-7 were obtained in the presence of triethylamine, whereas the respective S,N(4)-bis(gly... | ['Glycosylation', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Molecular Structure', 'Stereoisomerism', 'Triazoles'] | 19,237,153 | [['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['E05.196.867.519'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['G02.607.445.682'], ['D03.383.129.799']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sulfite reductase of Escherichia coli is a ferrisiderophore reductase. | A soluble ferrisiderophore reductase activity of Escherichia coli was purified to homogeneity and identified as the sulfite reductase. The pure enzyme catalyzes the reduction of ferric citrate, ferriaerobactin, ferrioxamin, ferricrocin, ferrichrome and ferrifusarinin by NADPH. Free flavins, riboflavin, FMN, FAD were ab... | ['Chromatography', 'Chromatography, Gel', 'Chromatography, Ion Exchange', 'Durapatite', 'Escherichia coli', 'Hydroxyapatites', 'Kinetics', 'NADH, NADPH Oxidoreductases', 'Oxidoreductases Acting on Sulfur Group Donors', 'Substrate Specificity'] | 8,389,549 | [['E05.196.181'], ['E05.196.181.400.250'], ['E05.196.181.400.383'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D01.029.260.700.675.374.075.025.300', 'D01.146.360.050.300',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Administration of an LHRH-antagonist to male mice: effects on in vivo secretion of hormones and on the growth of a transplantable human prostatic carcinoma. | The potent luteinizing hormone releasing hormone (LHRH) antagonist [N-Ac-D-p-Cl-Phe1,2,D-Trp3,D-Arg6,D-Ala10]-LHRH was chronically administered to male nude mice bearing the transplantable human hormone-dependent prostatic adenocarcinoma PC-82. Treatment of tumor-bearing male mice with a daily dose of 100 micrograms (4... | ['Adenocarcinoma', 'Animals', 'Female', 'Follicle Stimulating Hormone', 'Genitalia, Male', 'Gonadotropin-Releasing Hormone', 'Humans', 'Luteinizing Hormone', 'Male', 'Mammary Neoplasms, Experimental', 'Mice', 'Mice, Nude', 'Neoplasm Transplantation', 'Organ Size', 'Prostate', 'Prostatic Neoplasms', 'Rats', 'Testosteron... | 3,104,711 | [['C04.557.470.200.025'], ['B01.050'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['A05.360.444'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['B01.050.150.900.649.313.988.400.112.40... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Visually Impaired OLder people's Exercise programme for falls prevenTion (VIOLET): a feasibility study protocol. | INTRODUCTION: In the UK, 1 in 5 people aged 75 and over live with sight loss. Visually impaired older people (VIOP) have an above average incidence of falls and 1.3-1.9 times more likely to experience hip fractures, than the general population. Older people with eye diseases are ?3 times more likely than those with goo... | ['Accidental Falls', 'Aged', 'Exercise Therapy', 'Fear', 'Feasibility Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Patient Compliance', 'Quality of Life', 'Vision Disorders'] | 27,486,124 | [['N06.850.135.122'], ['M01.060.116.100'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['F01.470.361'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.500.600', 'F01.145.488.887.... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Perceived Stigma among Recipients of Mental Health Care in the General Canadian Population. | OBJECTIVES: The Mental Health Experiences Scale is a measure of perceived stigma, the perception of negative attitudes and behaviours by people with mental disorders. A recent Canadian survey (Canadian Community Health Survey-Mental Health) included this scale, providing an opportunity to describe perceived stigma in r... | ['Adult', 'Canada', 'Female', 'Humans', 'Male', 'Mental Disorders', 'Mental Health Services', 'Middle Aged', 'Prejudice', 'Social Stigma'] | 27,310,227 | [['M01.060.116'], ['Z01.107.567.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F04.408', 'N02.421.461'], ['M01.060.116.630'], ['F01.145.813.550', 'F01.829.595'], ['F01.145.813.840']] | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hashimoto's encephalopathy presenting with bipolar affective disorder. | OBJECTIVE: We report on a rare case of Hashimoto's encephalopathy associated with a bipolar affective disorder.CASE REPORT: A 32-year-old woman presented with a bipolar affective disorder and Hashimoto's thyroiditis. Neurological investigations (magnetic resonance imaging of the brain and cerebrospinal fluid) did not r... | ['Adult', 'Bipolar Disorder', 'Electroencephalography', 'Female', 'Humans', 'Prednisolone', 'Thyroiditis, Autoimmune'] | 15,898,968 | [['M01.060.116'], ['F03.084.500'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.432.769.795'], ['C19.874.871.102', 'C20.111.809']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The renin-angiotensin-aldosterone system during and after cardiopulmonary bypass. | Renin and aldosterone values were measured in 20 patients undergoing coronary bypass surgery. Renin activity rose to a peak during bypass, falling a little after bypass and surgery. Aldosterone levels rose significantly during bypass, and continued to do so afterwards. This demonstrates a typical physiological stress r... | ['Adult', 'Aged', 'Aldosterone', 'Blood Pressure', 'Cardiopulmonary Bypass', 'Humans', 'Intraoperative Period', 'Middle Aged', 'Postoperative Care', 'Postoperative Period', 'Renin', 'Renin-Angiotensin System'] | 6,359,485 | [['M01.060.116'], ['M01.060.116.100'], ['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E04.292.413'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374', 'N02.421.585.753.374'], ['M01.060.116.630'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.72... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Isolation, assay and biotyping of lactobacillary flora of the vagina]. | The results of the isolation, quantitation and biotyping of 120 strains of vaginal Lactobacillus are presented. The more effective culture media for isolation and different methods of pH measurement were investigated. Five different species of Lactobacillus were isolated in vaginal specimens (Lactobacillus acidophilus ... | ['Adolescent', 'Adult', 'Culture Media', 'Female', 'Humans', 'Hydrogen-Ion Concentration', 'Lactobacillus', 'Serotyping', 'Vagina'] | 6,518,085 | [['M01.060.057'], ['M01.060.116'], ['D27.720.470.305', 'E07.206'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.550.450.475'], ['E01.370.225.812.742', 'E01.370.225.875.150.125.890', 'E05.200.812.742', 'E05.200.875.150.125.890', 'E05.478.59... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The significance of fascial tissue of the upper eyelid in double eyelidplasty]. | The anatomical structure of fascial tissue of the upper eyelid is described in this article. It is emphasized that removing redundant fascial tissue is an important procedure in the double-eyelid operation of the upper eyelid. This is especially true for patients with baggy deformities or blepharochalasis. Based on thi... | ['Adolescent', 'Adult', 'Aged', 'Eyelids', 'Fascia', 'Female', 'Humans', 'Male', 'Middle Aged', 'Rhytidoplasty', 'Surgery, Plastic'] | 7,720,001 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A01.456.505.420.504', 'A09.371.337'], ['A02.340', 'A10.165.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.218.765', 'E04.680.275.700'], ['H02.403.810.788']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[Intensity of lipid peroxidation in the tissues of rats during hypokinesia]. | The intensity of lipid peroxidation in the homogenates and mitochondria of the liver, heart and skeletal muscle of hypokinetic rats was measured. The primary products of lipid peroxidation, i. e., diene conjugates, were accumulated in all tissues on hypokinesia days 3, 15, and 30. The content of the final product--malo... | ['Animals', 'Lipid Peroxides', 'Mitochondria', 'Mitochondria, Heart', 'Mitochondria, Liver', 'Mitochondria, Muscle', 'Rats', 'Restraint, Physical', 'Stress, Psychological'] | 4,057,932 | [['B01.050'], ['D01.248.497.158.685.750.637', 'D01.339.431.374.637', 'D01.650.550.750.600', 'D02.389.338.450', 'D10.440'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['A11.284.430.214.190.875.564.627.603', 'A11.284.835.626.627.603'], ['A11.284.430.214.190.875.564.461', 'A11.284.835.626.461'], ['A11.284.430.214... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The factorial structure of the Mini-Mental State Examination (MMSE) in Japanese dementia patients. | BACKGROUND: The Mini-Mental State Examination (MMSE) is one of the most commonly used instruments in the evaluation of global cognitive status. Few studies have investigated the relationship among its components in terms of factorial structure in Japanese individuals suffering from dementia. The aims of this study were... | ['Asian Continental Ancestry Group', 'Brief Psychiatric Rating Scale', 'Dementia', 'Factor Analysis, Statistical', 'Humans', 'Mental Recall'] | 20,534,132 | [['M01.686.508.200'], ['F04.711.513.653.083'], ['C10.228.140.380', 'F03.615.400'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enantiomerization pathway and atropochiral stability of the BINAP ligand: a density functional theory study. | A theoretical study of the enantiomerization pathway of BINAP, the paradigm of atropochiral ligands in asymmetric organometallic catalysis, is reported. Density functional theory was used with the B3PW91 functional and the 6-31G(d,p) basis set. The calculation level was validated through the study of the syn and anti e... | ['Hot Temperature', 'Ligands', 'Naphthalenes', 'Stereoisomerism', 'Thermodynamics'] | 25,202,766 | [['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['D27.720.470.480'], ['D02.455.426.559.847.638', 'D04.615.638'], ['G02.607.445.682'], ['G01.906']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Aberrant expressions of delta-protocadherins in the brain of Npc1 mutant mice. | Niemann-Pick type C1 (NPC1) disease is an autosomal recessive disorder characterized by dysmyelination and neurodegeneration, which can result in the death of patients in early childhood in some cases. Members of the delta-protocadherins (Pcdhs) play important roles in neurogenesis and brain development. In this study,... | ['Animals', 'Blotting, Western', 'Brain', 'Cadherins', 'Disease Models, Animal', 'Immunohistochemistry', 'In Situ Hybridization', 'Intracellular Signaling Peptides and Proteins', 'Mice', 'Mice, Mutant Strains', 'Mutation', 'Niemann-Pick Disease, Type C', 'Oligonucleotide Array Sequence Analysis', 'Proteins'] | 24,671,883 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A08.186.211'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.20... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Aspects of coracoacromial ligament anatomy of interest to the arthroscopic surgeon. | Examination was performed on 100 cadaveric specimens to demonstrate the anatomy of the coracoacromial (C-A) ligament. In a substantial number (34 specimens), the bipartite nature of the ligament and the breadth of its insertions were considerably more pronounced than usually perceived through the arthroscope. Supplemen... | ['Acromion', 'Arthroscopy', 'Cadaver', 'Endoscopy', 'Humans', 'Ligaments', 'Muscle, Skeletal', 'Ossification, Heterotopic', 'Rheumatic Diseases', 'Scapula', 'Shoulder'] | 8,679,034 | [['A02.835.232.087.783.261'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['C23.550.260.224'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.513', 'A10.165.669'], ['A02.633.567', 'A10.690.552.500'], ['C23.550.751'], ['C05.799', 'C17.300.775'], ['A02.835.232.08... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
From research to regulated: challenges in transferring methods. | The current decade has seen an evolution in biomarker research, with a breakthrough from traditional single analyte studies to simultaneous multiple analyte technologies, aided by the progressive development of research tools and the discovery of many novel biomarkers. It is foreseeable that the application of such tec... | ['Biomarkers', 'Biomedical Research', 'Chemistry Techniques, Analytical', 'Clinical Trials as Topic', 'Drug Approval', 'Humans', 'Medical Laboratory Science', 'Prognosis', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Translational Medical Research'] | 21,083,167 | [['D23.101'], ['H01.770.644.145'], ['E05.196'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.290.250', 'E05.337.300', 'I01.880.604.605.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.010.450', 'J01.897.480'], ['E01.789'], ['E05.318.370.725', 'E05.337.851', 'N05.... | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 |
Altered Fos-like immunoreactivity in terminal regions of the mesotelencephalic dopamine system is associated with reappearance of tyrosine hydroxylase immunoreactivity at the sites of focal 6-hydroxydopamine lesions in the nucleus accumbens. | The present study was undertaken in order to determine whether unilateral 6-hydroxydopamine (6-OHDA) lesions in the nucleus accumbens (Acb) affect basal Fos-like immunoreactivity (-LI) in terminal regions of the mesotelencephalic dopamine system. It was hypothesized that dopamine depletion in the Acb would alter activa... | ['Animals', 'Brain', 'Dopamine', 'Immunohistochemistry', 'Male', 'Nucleus Accumbens', 'Organ Specificity', 'Oxidopamine', 'Proto-Oncogene Proteins c-fos', 'Rats', 'Rats, Sprague-Dawley', 'Reference Values', 'Telencephalon', 'Tyrosine 3-Monooxygenase'] | 8,930,333 | [['B01.050'], ['A08.186.211'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of two platelet-rich plasma processing methods and two platelet-activation techniques for use in llamas and alpacas. | OBJECTIVE To evaluate 2 processing methods (commercial kit vs conical tube centrifugation) for preparing platelet rich plasma (PRP) for use in llamas and alpacas. SAMPLES Blood samples (30 mL each) aseptically collected from 6 healthy llamas and 6 healthy alpacas. PROCEDURES PRP was prepared from blood samples by use o... | ['Animals', 'Blood Component Removal', 'Blood Platelets', 'Camelids, New World', 'Centrifugation', 'Intercellular Signaling Peptides and Proteins', 'Platelet-Rich Plasma', 'Transforming Growth Factor beta'] | 27,805,447 | [['B01.050'], ['E02.120'], ['A11.118.188', 'A15.145.229.188'], ['B01.050.150.900.649.313.500.190.090'], ['E05.181'], ['D12.644.276', 'D12.776.467', 'D23.529'], ['A12.207.152.693.600', 'A12.207.270.695.600', 'A15.145.693.600'], ['D12.644.276.374.687', 'D12.644.276.954.775', 'D12.776.467.374.687', 'D12.776.467.942.775', ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulation of bacterial cell polarity by small GTPases. | Bacteria are polarized with many proteins localizing dynamically to specific subcellular sites. Two GTPase families have important functions in the regulation of bacterial cell polarity, FlhF homologues and small GTPases of the Ras superfamily. The latter consist of only a G domain and are widespread in bacteria. The r... | ['Bacterial Proteins', 'Cell Movement', 'Cell Polarity', 'Monomeric GTP-Binding Proteins', 'Myxococcus xanthus', 'Protein Structure, Secondary'] | 24,655,121 | [['D12.776.097'], ['G04.198', 'G07.568.500.180'], ['G04.250'], ['D08.811.277.040.330.300.400', 'D12.644.360.525', 'D12.776.157.325.515', 'D12.776.476.525'], ['B03.660.125.500.605.900'], ['G02.111.570.820.709.600']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stages of change in physical activity behavior in children and adolescents with cerebral palsy. | PURPOSE: To identify facilitators and barriers frequently experienced by families of children with cerebral palsy (CP) and associated with being at the pre-intention, intention and action stages for physical activity.METHOD: Qualitative study involving in-depth focus group interviews with 33 ambulatory children and ado... | ['Adolescent', 'Adult', 'Attitude to Health', 'Cerebral Palsy', 'Child', 'Exercise', 'Female', 'Focus Groups', 'Health Behavior', 'Humans', 'Intention', 'Interviews as Topic', 'Male', 'Middle Aged', 'Motor Activity', 'Parents', 'Qualitative Research', 'Social Environment', 'Social Participation', 'Social Support', 'Spo... | 23,336,120 | [['M01.060.057'], ['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['C10.228.140.140.254'], ['M01.060.406'], ['G11.427.410.698.277', 'I03.350'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.650', 'F02.463.306'], ['E05.318.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occ... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
The modification of polyurethane foams using new boroorganic polyols (II) polyurethane foams from boron-modified hydroxypropyl urea derivatives. | The work focuses on research related to determination of application possibility of new, ecofriendly boroorganic polyols in rigid polyurethane foams production. Polyols were obtained from hydroxypropyl urea derivatives esterified with boric acid and propylene carbonate. The influence of esterification type on propertie... | ['Boron Compounds', 'Hot Temperature', 'Organometallic Compounds', 'Polyurethanes', 'Urea'] | 24,587,721 | [['D01.132', 'D02.203'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['D02.691'], ['D02.241.081.251.944.750', 'D05.750.716.650', 'D25.720.327.782', 'D25.720.716.650', 'J01.637.051.720.327.782', 'J01.637.051.720.716.650', 'J01.6... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Does the Thermal Damage Estimate Correlate With the Magnetic Resonance Imaging Predicted Ablation Size After Laser Interstitial Thermal Therapy? | BACKGROUND: Magnetic resonance guided laser induced thermal therapy (LITT) is a minimally invasive method to treat a wide range of intracranial pathologies. The Arrhenius model is used to generate a thermal damage estimate (TDE) predicting ablation extent.OBJECTIVE: Evaluation and correlation of the TDE to magnetic res... | ['Adult', 'Aged', 'Brain', 'Brain Neoplasms', 'Epilepsy', 'Female', 'Humans', 'Laser Therapy', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Sensitivity and Specificity', 'Surgery, Computer-Assisted', 'Young Adult'] | 28,962,036 | [['M01.060.116'], ['M01.060.116.100'], ['A08.186.211'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.71... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Outcome prediction in terms of functional disability and mortality at 1 year among ICU-admitted severe stroke patients: a prospective epidemiological study in the south of the European Union (Evascan Project, Andalusia, Spain). | OBJECTIVES: To analyse 1-year mortality and functional disability outcomes and resource use in critical stroke patients admitted to ICU.DESIGN AND SETTING: Multi-centre, prospective, observational study in 28 Spanish hospitals. PATIENTS. Patients admitted for acute stroke from March-August 1999.INTERVENTION: Collection... | ['Aged', 'Humans', 'Intensive Care Units', 'Logistic Models', 'Middle Aged', 'Outcome Assessment, Health Care', 'Prognosis', 'Prospective Studies', 'Spain', 'Stroke', 'Treatment Outcome'] | 12,756,437 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N05.715.360.750.695.470', 'N06.850.520.830.500.525', 'N06.850.520.830.600.80... | ['Named Groups [M]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
[High flow nasal cannula oxygen therapy in the treatment of acute bronchiolitis in neonates]. | OBJECTIVE: To determine whether the availability of heated humidified high-flow nasal cannula (HFNC) therapy was associated with a decrease in need for mechanical ventilation in neonates hospitalised with acute bronchiolitis.METHODS: A combined retrospective and prospective (ambispective) cohort study was performed in ... | ['Acute Disease', 'Bronchiolitis', 'Cannula', 'Cohort Studies', 'Female', 'Humans', 'Infant, Newborn', 'Male', 'Oxygen Inhalation Therapy', 'Prospective Studies', 'Respiration, Artificial', 'Retrospective Studies'] | 27,068,070 | [['C23.550.291.125'], ['C01.748.099.135', 'C08.127.446.135', 'C08.381.495.146.135', 'C08.730.099.135'], ['E07.132.125'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E02.880.690'], ['E05.318.372.500.750.625', 'N05.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Protective effect of infliximab on ischemia/reperfusion injury in a rat ovary model: biochemical and histopathologic evaluation. | OBJECTIVE: The aim of this study was to investigate the effect of infliximab on experimentally induced ovarian ischemia/reperfusion injury (IRi).STUDY DESIGN: A total of 42 female rats were equally divided into 6 experimental groups; group 1: sham operation, group 2: 3-h ischemia, group 3 and 4: 3-h ischemia, 3-h reper... | ['Animals', 'Antibodies, Monoclonal', 'Antioxidants', 'Catalase', 'Female', 'Infliximab', 'Malondialdehyde', 'Nitric Oxide', 'Ovary', 'Rats', 'Rats, Sprague-Dawley', 'Reperfusion Injury', 'Torsion Abnormality'] | 24,169,036 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D08.811.682.732.332'], ['D12.776.124.486.485.114.224.608', 'D12.776.124.790.651.114.224.537', 'D12.776.377.715.548.114.224.642'], ['D02.047.700'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An assessment of oral self-care among Romanian dental students using the Hiroshima University--Dental Behavioural Inventory. | OBJECTIVE: To determine the differences in oral self-care levels between 322 Romanian dental students.MATERIALS AND METHODS: The design of the study was a cross-sectional survey of dental students in Romania. The examination was based upon responses to a questionnaire entitled 'Hiroshima University--Dental Behavioural ... | ['Adult', 'Dental Devices, Home Care', 'Educational Status', 'Epidemiologic Methods', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Oral Hygiene', 'Romania', 'Sex Factors', 'Students, Dental', 'Toothbrushing'] | 17,722,434 | [['M01.060.116'], ['E06.186.250', 'E06.761.726.292', 'E07.222.250'], ['N01.824.196'], ['E05.318', 'N06.850.520'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.547.600', 'E06.761.726'], ['Z01.542.248.764'], ['N05.715.350.675', 'N06.850.490.875'], ['M01.848.769.519'], ['E... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A note on the interpretation of results of supplementation trials. | In a supplementation trial to study the effect of the supplemental treatment on some response variable of interest, the variable is often measured twice from each subject, namely; before (x) and after (y) the trial period. The difference between y and x (Z = y - x) is then computed for each subject. The Z and x values ... | ['Clinical Trials as Topic', 'Diet', 'Food, Fortified', 'Models, Biological', 'Regression Analysis', 'Statistics as Topic'] | 7,355,804 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['G07.203.650.240'], ['G07.203.300.515', 'J02.500.515'], ['E05.599.395'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
The detection of loose bodies in the elbow: the value of MRI and CT arthrography. | Our aim was to determine the clinical value of MRI and CT arthrography in predicting the presence of loose bodies in the elbow. A series of 26 patients with mechanical symptoms in the elbow had plain radiography, MRI and CT arthrography, followed by routine arthroscopy of the elbow. The location and number of loose bod... | ['Adolescent', 'Adult', 'Arthrography', 'Elbow Joint', 'Female', 'Humans', 'Joint Diseases', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Tomography, X-Ray Computed'] | 15,855,372 | [['M01.060.057'], ['M01.060.116'], ['E01.370.350.700.070'], ['A02.835.583.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Development of a screen to identify selective small molecules active against patient-derived metastatic and chemoresistant breast cancer cells. | INTRODUCTION: High failure rates of new investigational drugs have impaired the development of breast cancer therapies. One challenge is that excellent activity in preclinical models, such as established cancer cell lines, does not always translate into improved clinical outcomes for patients. New preclinical models, w... | ['Animals', 'Breast Neoplasms', 'Caspases', 'Cell Death', 'Cell Line, Tumor', 'Cell Proliferation', 'Disease Models, Animal', 'Drug Evaluation, Preclinical', 'Drug Resistance, Neoplasm', 'Drug Screening Assays, Antitumor', 'Female', 'Humans', 'Immunophenotyping', 'Neoplasm Metastasis', 'Phenotype', 'Poly(ADP-ribose) Po... | 23,879,992 | [['B01.050'], ['C04.588.180', 'C17.800.090.500'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['G04.146'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.290.750', 'E05... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Persistent mullerian duct syndrome and transverse testicular ectopia: embryology, presentation, and management. | BACKGROUND: The finding of persistent mullerian duct syndrome (PMDS) with transverse testicular ectopia (TTE) is rare. We present nonidentical triplets with PMDS with TTE.CASES: Triplet A presented with a right inguinal hernia and left nonpalpable testis at 4 months of age. Ultrasound demonstrated 1 testis in the right... | ['Abnormalities, Multiple', 'Choristoma', 'Combined Modality Therapy', 'Cryptorchidism', 'Follow-Up Studies', 'Hernia, Inguinal', 'Humans', 'Infant', 'Laparotomy', 'Male', 'Mullerian Ducts', 'Syndrome', 'Testis', 'Treatment Outcome', 'Triplets', 'Urologic Surgical Procedures, Male'] | 18,082,721 | [['C16.131.077'], ['C23.300.250'], ['E02.186'], ['C12.294.829.258', 'C12.706.258', 'C16.131.939.258', 'C19.391.829.258'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C23.300.707.374.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E04.406'], ['A... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Prognosis of basic somatic characteristics of humans in expert examination of fragments of human body]. | To develop a method of assessing human body somatometric parameters by its fragmentation, we used individual data on the series G. van Vark (1975) from corpses of 62 males and 39 females aged from 23 to 95 years. Statistical processing with SPSS package calculated regression equations allowing prediction of head size, ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anthropometry', 'Body Weights and Measures', 'Cadaver', 'Female', 'Forensic Pathology', 'Humans', 'Male', 'Middle Aged', 'Prognosis'] | 16,826,841 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E01.370.600.115.100', 'E05.041.124', 'G07.100.100'], ['C23.550.260.224'], ['H02.403.330.300', 'H02.403.650.249', 'I01.198.780.937.460'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
[Induction of the monooxygenase system and the transport of xenobiotics in the kidney]. | Phenobarbital (50 mg/kg) and benzonal (35 mg/kg) orally for 4 days and 3-methylcholanthrene (20 mg/kg) subcutaneously increased the excretion and tubular maximal transport of cardiotrast (diodrast) in rats. The inductors of the monooxigenase system seem to stimulate the renal transport of xenobiotics. | ['Animals', 'Barbiturates', 'Enzyme Induction', 'Kidney Tubules', 'Methylcholanthrene', 'Oxygenases', 'Phenobarbital', 'Rats'] | 3,622,832 | [['B01.050'], ['D03.383.742.698.253'], ['G05.308.320.200'], ['A05.810.453.736.560'], ['D02.455.426.559.847.149.500', 'D04.615.149.500'], ['D08.811.682.690'], ['D03.383.742.698.253.650'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Family preservation: a potential not yet realized. | When they received widespread promotion and support beginning in the 1980s, family preservation services seemed to hold much promise for the child welfare field, and for the lives of families and children. Unfortunately, this promise has never been fully realized throughout the United States. This article traces the re... | ['Child', 'Child Custody', 'Child Welfare', 'Family', 'Humans', 'Public Policy', 'Social Work', 'United States'] | 10,659,390 | [['M01.060.406'], ['I01.880.787.293.370'], ['I01.880.787.293'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.655.500.608', 'I01.880.604.825.608', 'N03.623.500.608'], ['I01.880.792', 'N02.421.849'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Magnetic resonance imaging in a family with hereditary cerebral arteriovenous malformations. | Because of a family history of neurologic problems and the documentation of three vascular lesions in one patient, we evaluated 18 members representing three family generations with magnetic resonance imaging. Of these, eight were normal, two had abnormalities probably not related to arteriovenous malformation, one sca... | ['Adult', 'Brain', 'Cerebral Hemorrhage', 'Humans', 'Intracranial Arteriovenous Malformations', 'Magnetic Resonance Imaging', 'Male', 'Pedigree', 'Tomography, X-Ray Computed'] | 2,610,730 | [['M01.060.116'], ['A08.186.211'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.520', 'C10.500.190.500', 'C14.240.850.750.295', 'C14.240.850.875.500', 'C14.907.150.295', 'C14.907.253.560.400', 'C16.131.240.850.750.295', 'C1... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Monoamine metabolism and its responses to food deprivation in the brain of Zucker rats. | Monoamines and their metabolites levels were simultaneously measured by high-performance liquid chromatography in brain regions of lean and fatty Zucker rats when fed ad lib and deprived of food for 72 hr to evaluate each monoamine metabolism. Metabolite/monoamine ratios were shown for brevity to represent its metaboli... | ['Animals', 'Body Weight', 'Brain', 'Dopamine', 'Epinephrine', 'Food Deprivation', 'Male', 'Neurotransmitter Agents', 'Norepinephrine', 'Rats', 'Rats, Zucker', 'Serotonin'] | 2,907,160 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A08.186.211'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', ... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Potent oxadiazole CGRP receptor antagonists for the potential treatment of migraine. | A pharmacophore model was built, based on known CGRP receptor antagonists, and this was used to aid the identification of novel leads. Analogues were designed, modelled and synthesised which incorporated alternative 'LHS' fragments linked via either an amide or urea to a privileged 'RHS' fragment commonly found in CGRP... | ['Administration, Oral', 'Animals', 'Calcitonin Gene-Related Peptide Receptor Antagonists', 'Drug Design', 'Migraine Disorders', 'Models, Molecular', 'Molecular Structure', 'Oxadiazoles', 'Rats'] | 20,097,071 | [['E02.319.267.100'], ['B01.050'], ['D27.505.519.270', 'D27.505.696.663.850.014.610', 'D27.505.954.427.040.409'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['C10.228.140.546.399.750'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['D03.383.129.462.580'], ['B01.050.150.900.649.313.992.635.505.70... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Pyp3 PTPase acts as a mitotic inducer in fission yeast. | The p34cdc2 M-phase kinase is regulated by inhibitory phosphorylation of Tyr15, largely through the actions of the p107wee1 tyrosine kinase and p80cdc25 protein tyrosine phosphatase (PTPase). In this study we demonstrate that a second PTPase, encoded by pyp3, also contributes to tyrosyl dephosphorylation of p34cdc2. Py... | ['Alleles', 'Amino Acid Sequence', 'Base Sequence', 'CDC2 Protein Kinase', 'Cell Cycle Proteins', 'DNA, Fungal', 'Enzyme Activation', 'Fungal Proteins', 'Genes, Suppressor', 'Humans', 'Mitosis', 'Molecular Sequence Data', 'Mutation', 'Nuclear Proteins', 'Phosphorylation', 'Protein Kinases', 'Protein Tyrosine Phosphatas... | 1,464,318 | [['G05.360.340.024.340.030'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.913.696.620.682.700.646.500.500.250', 'D08.811.913.696.620.682.700.646.500.984.500', 'D12.644.360.250.067.249', 'D12.644.360.250.580.500', 'D12.776.167.200.067.249', 'D12.776.16... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
High-resolution depth electrode localization and imaging in patients with pharmacologically intractable epilepsy. | Localization and targeting of depth electrodes in specific regions of the human brain is critical for accurate clinical diagnoses and treatment as well as for neuroscientific electrophysiological research. By using high-resolution magnetic resonance imaging combined with 2D computational unfolding, the authors present ... | ['Electric Stimulation Therapy', 'Electrodes, Implanted', 'Epilepsy', 'Hippocampus', 'Humans', 'Imaging, Three-Dimensional', 'Magnetic Resonance Imaging', 'Tomography, X-Ray Computed'] | 18,377,264 | [['E02.331', 'E02.779.468', 'E02.831.535.468'], ['E07.305.250.319', 'E07.695.202'], ['C10.228.140.490'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.825.500'], ['E01.370.350.350.810', 'E01.370.350.600.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
New records of Anastrepha (Diptera: Tephritidae) from Paraguay. | This work presents new distribution records in Paraguay for 19 fruit fly species of the genus Anastrepha Schiner, including four new records for the country: A. alveatoides Blanchard, A. australis (Blanchard), A. obliqua (Macquart) and A. pastranai Blanchard. Additionally, an updated list of the 26 Anastrepha species p... | ['Animals', 'Drosophila', 'Paraguay', 'Tephritidae', 'Wings, Animal'] | 33,055,953 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['Z01.107.757.656'], ['B01.050.500.131.617.720.500.500.750.850'], ['A13.395.823']] | ['Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Knowledge Regarding Influenza and Influenza Vaccination in General Population: Results of a National Survey in Poland. | For the past 10 years, influenza vaccination coverage rate in Poland remains at a low 3% threshold. This low rate may be related to the unsatisfactory knowledge of vaccination, influenza, and misperception of health risks in the general population. To examine these issues, we used an online questionnaire consisting of ... | ['Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Influenza Vaccines', 'Influenza, Human', 'Male', 'Poland', 'Surveys and Questionnaires', 'Vaccination'] | 29,995,213 | [['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.215.894.899.302'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['Z01.542.248.679'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['E02.095.465.425.400.530.890', 'E05.478.550.600.890', 'N02.42... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Thermal migration in biological transport? | It is shown by thermodynamic arguments and by semiquantitative considerations that the contribution of thermal migration to biological transport is likely to be small. | ['Biological Transport', 'Biophysical Phenomena', 'Biophysics', 'Temperature', 'Thermodynamics'] | 5,863,434 | [['G03.143'], ['G01.154'], ['H01.158.344', 'H01.671.100'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['G01.906']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of light intensity and nitrogen starvation on CO2 fixation and lipid/carbohydrate production of an indigenous microalga Scenedesmus obliquus CNW-N. | Engineering strategies were applied to improve the CO(2) fixation rate and carbohydrate/lipid production of a Scenedesmus obliquus CNW-N isolate. The light intensity that promotes cell growth, carbohydrate/lipid productivity, and CO(2) fixation efficiency was identified. Nitrogen starvation was also employed to trigger... | ['Biomass', 'Bioreactors', 'Carbohydrate Metabolism', 'Carbon Dioxide', 'Light', 'Lipid Metabolism', 'Nitrogen', 'Scenedesmus'] | 22,209,130 | [['G16.500.275.157.100', 'N06.230.124.100'], ['E07.115', 'J01.897.120.115'], ['G02.111.158', 'G03.191'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['G03.458'], ['D01.268.604', 'D01.362.625'], ['B01.650.940.150.800']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The effects of diet and corticosteroid-induced immune suppression during infection by Haemonchus contortus in lambs. | To evaluate the effects of Diet and corticosteroid-induced immune suppression during infection by Haemonchus contortus, 28 lambs were allocated to one of four groups treated as follows: Group Basal Diet - Normal; Group Basal Diet - Immune-Suppressed; Group Supplemented Diet - Normal; and Group Supplemented Diet - Immun... | ['Animals', 'Diet', 'Female', 'Haemonchiasis', 'Haemonchus', 'Immunoglobulin G', 'Immunosuppression', 'Male', 'Methylprednisolone Hemisuccinate', 'Parasite Egg Count', 'Sheep', 'Sheep Diseases'] | 26,391,820 | [['B01.050'], ['G07.203.650.240'], ['C01.610.335.508.700.775.825.400'], ['B01.050.500.500.294.400.968.746.410'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['E02.095.465.425.450', 'E05.478.610'], ['D04.210.500.745.432.769.795.539.500'], ['E01.370.225.932.6... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Host-gene control of C-type RNA tumor virus: inheritance of the group-specific antigen of murine leukemia virus. | Genetic studies were aimed at elucidation of the mechanism of inheritance of the group-specific antigen of the murine leukemia virus. Two approaches have been used. First, a classical Mendelian hybridization experiment was performed with mice of the high-leukemia AKR strain and the low-leukemia C57L strain; the first f... | ['Animals', 'Antigens', 'Antigens, Viral', 'Complement Fixation Tests', 'Crosses, Genetic', 'Embryo, Mammalian', 'Female', 'Genes, Dominant', 'Genetic Linkage', 'Guinea Pigs', 'Hybridization, Genetic', 'Immune Sera', 'Leukemia Virus, Murine', 'Male', 'Mice', 'Mice, Inbred Strains', 'Rats', 'Recombination, Genetic', 'Sp... | 4,332,013 | [['B01.050'], ['D23.050'], ['D23.050.327'], ['E01.370.225.812.735.150', 'E05.200.812.735.150', 'E05.478.594.760.150'], ['E05.393.281'], ['A16.254'], ['G05.360.340.024.340.240', 'G05.420.320'], ['G05.348'], ['B01.050.150.900.649.313.992.550'], ['E05.820.150.390', 'G05.090.390'], ['A12.207.152.846.500', 'D12.776.124.486.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
"Attenuating Anxieties": A grounded theory study of mental health nurses' responses to clients with suicidal behaviour. | AIMS AND OBJECTIVES: To develop a grounded theory to explain mental health nurses' responses to clients with suicidal behaviour.BACKGROUND: Mental health nurses are an integral part of the multi-disciplinary teams supporting people who experience suicidal behaviour, yet limited research is available that explores how n... | ['Adult', 'Anxiety', 'Attitude of Health Personnel', 'Female', 'Grounded Theory', 'Humans', 'Ireland', 'Male', 'Mental Disorders', 'Nursing Methodology Research', 'Psychiatric Nursing', 'Suicidal Ideation', 'Suicide'] | 30,431,681 | [['M01.060.116'], ['F01.470.132'], ['F01.100.050', 'N05.300.100'], ['H01.770.644.241.424'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.467', 'Z01.639.587'], ['F03'], ['H01.770.644.145.390.634', 'H02.478.395.634', 'N04.590.233.508.613.634'], ['H02.478.676.710', 'N02.421.533.778'], ['F01.145.126.980.875.1... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Hepatoprotective and antioxidant activities of Vernonia amygdalina on acetaminophen-induced hepatic damage in mice. | Vernonia amygdalina Del. (Family Compositae) is used in Nigerian folk medicine as a tonic and remedy against constipation, fever, high blood pressure, and many infectious diseases. We have evaluated the hepatoprotective and antioxidant effects of an aqueous extract of V. amygdalina leaves against acetaminophen-induced ... | ['Acetaminophen', 'Alanine Transaminase', 'Alkaline Phosphatase', 'Animals', 'Antioxidants', 'Aspartate Aminotransferases', 'Bilirubin', 'Catalase', 'Chemical and Drug Induced Liver Injury', 'L-Lactate Dehydrogenase', 'Lipid Peroxidation', 'Liver', 'Liver Diseases', 'Medicine, Traditional', 'Mice', 'Nigeria', 'Oxidativ... | 17,201,640 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['D08.811.913.477.700.100'], ['D08.811.277.352.650.035'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D08.811.913.477.700.225'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Characterization of alpha 1-adrenoceptors which mediate chronotropy in neonatal rat cardiac myocytes. | 1. In the present study, we investigated the effect of culture on alpha 1-adrenoceptors that mediate chronotropy and on alpha 1-adrenergic signal transduction in neonatal rat cardiac myocytes. 2. The spontaneous beating rate of neonatal rat myocytes after 3 or 7 days in culture was 37.4 +/- 4.2 or 102.0 +/- 4.3 beats m... | ['Animals', 'Animals, Newborn', 'Cells, Cultured', 'Cholesterol', 'GTP-Binding Proteins', 'Heart', 'Heart Rate', 'Immunoblotting', 'Inositol 1,4,5-Trisphosphate', 'Membranes', 'Myocardium', 'Phospholipids', 'Prazosin', 'Rats', 'Rats, Wistar', 'Receptors, Adrenergic, alpha-1', 'Signal Transduction', 'Yohimbine'] | 7,900,969 | [['B01.050'], ['B01.050.050.282'], ['A11.251'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['A07.541'], ['E01.370.600.875.500', 'G09.330.380.500'], ['E05.478.566.320', 'E05.601.470.320'], ['D02.033.800.519.400.350', 'D09.853.519.400.350', '... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A cross-sectional study to compare changes in the prevalence and risk factors for feline obesity between 1993 and 2007 in New Zealand. | It has been suggested that the prevalence of feline obesity has increased recently in parallel with the prevalence of obesity in the human population. We had previously determined the prevalence of obesity in an urban New Zealand population of cats in 1993. This study was conducted to determine the prevalence and risk ... | ['Animals', 'Cat Diseases', 'Cats', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'New Zealand', 'Obesity', 'Prevalence', 'Risk Factors', 'Statistics, Nonparametric', 'Surveys and Questionnaires', 'Urban Population'] | 22,703,979 | [['B01.050'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.639.760.747', 'Z01.678.100.747'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Hierarchical population genetic structure in a direct developing antarctic marine invertebrate. | Understanding the relationship between life-history variation and population structure in marine invertebrates is not straightforward. This is particularly true of polar species due to the difficulty of obtaining samples and a paucity of genomic resources from which to develop nuclear genetic markers. Such knowledge, h... | ['Amplified Fragment Length Polymorphism Analysis', 'Animals', 'Antarctic Regions', 'Aquatic Organisms', 'Bays', 'Genetic Loci', 'Genetics, Population', 'Genotyping Techniques', 'Invertebrates', 'Polymorphism, Genetic'] | 23,691,125 | [['E05.393.290.382', 'E05.393.620.500.324'], ['B01.050'], ['Z01.158'], ['B05.080', 'G16.500.275.725.500.650.075'], ['G01.311.625.080'], ['G05.360.340.024.380'], ['H01.158.273.343.335'], ['E05.393.442'], ['B01.050.500'], ['G05.365.795']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
[Results of a multicentric clinical study of mezlocillin in Japan (author's transl)]. | In a clinical trial including 701 patients 6-((R)-2-[3-methylsulfonyl-2-oxo-imidazolidine-1-carboxamido]-2-phenyl-acetamido)-penicillanic acid sodium salt (mezlocillin, Baypen) proved effective in the treatment of severe infections. It showed a particularly high efficacy in septicaemia and endocarditis and in purulent ... | ['Adolescent', 'Adult', 'Aged', 'Aging', 'Anti-Bacterial Agents', 'Bacterial Infections', 'Child', 'Child, Preschool', 'Clinical Trials as Topic', 'Female', 'Humans', 'Infant', 'Japan', 'Male', 'Mezlocillin', 'Middle Aged', 'Penicillins'] | 396,930 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis. | Mitochondrial heat-shock protein hsp60 functions in the folding of proteins imported into mitochondria. Folding occurs at the surface of hsp60 in an ATP-mediated reaction, followed by release of the bound polypeptides. We propose that hsp60 catalyses protein folding. | ['Adenosine Triphosphate', 'Animals', 'Ethylmaleimide', 'Heat-Shock Proteins', 'Humans', 'Kinetics', 'Mitochondria', 'Neurospora', 'Protein Conformation', 'Proton-Translocating ATPases', 'Tetrahydrofolate Dehydrogenase'] | 2,528,694 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D02.241.081.337.502.524.418', 'D02.478.440.418', 'D03.383.129.578.399.418'], ['D12.776.580.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['A11.284.430.214.190.875.564', 'A11.284.835.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interactions of novel morpholine and hexamethylene derivatives of anthracycline antibiotics with DNA. | Doxorubicin (DOX), daunorubicin (DRB), epidoxorubicin (EDOX) and their analogues with a 3'-NH2 group in daunosamine form a covalent bond with a 2-NH2 group of guanine via a methylene group from formaldehyde (CH2O). It is assumed that a Schiff base type intermediate is formed between CH2O and the 3'-NH2 group in the rea... | ['Anthracyclines', 'Bacteriophage T7', 'Binding Sites', 'DNA, Viral', 'Daunorubicin', 'Doxorubicin', 'Morpholines', 'RNA, Viral', 'Schiff Bases', 'Transcription, Genetic'] | 15,540,609 | [['D02.455.426.559.847.562.050', 'D04.615.562.050', 'D09.408.051.059'], ['B04.123.150.700.230', 'B04.123.205.891.230', 'B04.280.090.700.230'], ['G02.111.570.120'], ['D13.444.308.568'], ['D02.455.426.559.847.562.050.200', 'D04.615.562.050.200', 'D09.408.051.059.200'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hydrogen Bonds Dictate O2 | Six directed hydrogen bonding (H-bonding) interactions allow for the reversible capture and reduction of dioxygen to a trans-1,2-peroxo within a tripodal zinc(II) framework. Spectroscopic studies of the dizinc peroxides, as well as on model zinc diazides, suggest H-bonding contributions serve a dominant role for the bi... | ['Heme', 'Hydrogen Bonding', 'Models, Molecular', 'Molecular Structure', 'Oxygen', 'Peroxides', 'Zinc'] | 30,074,788 | [['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['G02.282'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['D01.268.185.550', 'D01.362.670'], ['D01.248.497.158.685.750', 'D01.339.431.374', 'D01.650.550.750', 'D02.389.338'], ['D01.268.556.940', 'D01.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Estimating costs associated with a community outbreak of meningococcal disease in a colombian Caribbean city. | Meningococcal disease is a serious and potentially life-threatening infection that is caused by the bacterium Neisseria meningitidis (N. meningitidis), and it can cause meningitis, meningococcaemia outbreaks and epidemics. The disease is fatal in 9-12% of cases and with a death rate of up to 40% among patients with men... | ['Anti-Bacterial Agents', 'Antibiotic Prophylaxis', 'Ceftriaxone', 'Child', 'Child, Preschool', 'Colombia', 'Cost of Illness', 'Disease Outbreaks', 'Female', 'Humans', 'Male', 'Meningococcal Infections', 'Neisseria meningitidis', 'Sentinel Surveillance'] | 25,395,916 | [['D27.505.954.122.085'], ['E02.319.162.150', 'E02.319.703.150'], ['D02.065.589.099.249.190.190.155', 'D02.886.665.074.190.190.155', 'D03.633.100.300.249.190.190.155'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.107.757.284'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], [... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mid- and long-term effects of family constellation seminars in a general population sample: 8- and 12-month follow-up. | In a previous randomized controlled trial (RCT), short-term efficacy of family constellation seminars (FCSs) in a general population sample was demonstrated. In this article, we examined mid- and long-term stability of these effects. Participants were 104 adults (M = 47 years; SD = 9; 84% female) who were part of the i... | ['Adult', 'Family Relations', 'Family Therapy', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Motivation', 'Social Adjustment', 'Stress, Psychological', 'Surveys and Questionnaires', 'Time', 'Treatment Outcome'] | 25,264,190 | [['M01.060.116'], ['F01.829.263.370', 'I01.880.853.150.439'], ['F04.754.864.581.273'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.658', 'F01.752.543.500.750'], ['F01.145.813.621'], ['F01.145.126.9... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The morphology of diaphragmatic defects in hepatic hydrothorax: thoracoscopic finding. | BACKGROUND: Until now, the pathophysiology of hepatic hydrothorax has been moot. We discuss (on the basis of gross videothoracoscopy findings in 11 cases and the literature) the pathogenesis and clinical presentation of this complex condition.METHODS: We prospectively studied 11 patients (age, 31-73 years; 6 men and 5 ... | ['Aged', 'Diaphragm', 'Female', 'Humans', 'Hydrothorax', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Prospective Studies', 'Thoracoscopy'] | 15,999,054 | [['M01.060.116.100'], ['A02.633.567.900.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.528.476'], ['C06.552.630', 'C23.550.355.412'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E01.370.388.250.840', 'E04.502.250.840', 'E04.928.752']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Measurement and specification of the envelope correlation between two narrow bands of noise. | Empirical measurements show that when two independent, narrow-band, Gaussian noises are 'mixed' or combined according to the method specified by Licklider and Dzendolet (1948) [Science, 107, 121-124], the correlation coefficient between the envelopes (rExy) of the two resulting narrow-band noises is approximately equal... | ['Hearing', 'Humans', 'Models, Psychological', 'Noise'] | 2,061,207 | [['F02.830.816.263', 'G07.888.500', 'G11.561.790.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.695'], ['G01.750.770.776.567', 'G16.500.275.600', 'N06.230.400', 'N06.850.460.610']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Influence of hepatitis delta virus infection on progression to cirrhosis in chronic hepatitis type B. | Serological markers of hepatitis delta virus (HDV) infection were found in 18 (12%) of 146 consecutive patients with chronic hepatitis B, and the characteristics of patients who had antibody to HDV (anti-HDV-positive) were analyzed. During one to 15 years of follow-up, histological deterioration was documented in 77% o... | ['Adolescent', 'Adult', 'Aged', 'Antibodies, Viral', 'Female', 'Hepatitis B', 'Hepatitis B Surface Antigens', 'Hepatitis D', 'Hepatitis Delta Virus', 'Hepatitis, Chronic', 'Humans', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Probability'] | 3,559,292 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['D23.050.327.495.500.475'], ['C01.925.440.450', 'C01.925.782.450', 'C06.552.380.70... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[The asthmatic child]. | Asthma is the most frequent chronic pediatric disease. Management is based on assessment of severity and should normalize lifestyle as well as pulmonary function. Mild asthma is treated with intermittent beta-2-agonists. Moderate asthma should receive non-steroids prophylactic anti-inflammatory drugs. Immunotherapy sho... | ['Asthma', 'Child', 'Humans', 'Infant', 'Status Asthmaticus'] | 1,296,319 | [['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C08.127.108.880', 'C08.674.095.880', 'C20.543.480.680.095.880']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Anti-EGFR therapeutic efficacy correlates directly with inhibition of STAT3 activity. | Several agents targeting the epidermal growth factor receptor (EGFR) have been FDA-approved to treat cancer patients with varying tumor types including metastatic colorectal cancer. Many patients treated with anti-EGFR therapy however do not respond and those that do initially respond often acquire resistance. Here we ... | ['Animals', 'Antibodies, Monoclonal, Humanized', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Cetuximab', 'Colonic Neoplasms', 'Drug Resistance, Neoplasm', 'ErbB Receptors', 'Erlotinib Hydrochloride', 'Heterografts', 'Humans', 'Mice, Inbred BALB C', 'Quinazolines', 'Receptor-Like Protein Tyrosine Phosphatases, Class 2... | 24,556,630 | [['B01.050'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.776.124.486.485.114.224.060.750', 'D12.776.124.790.651.114.224.060.750', 'D12.776.377.715.548.114.224.200.750'], ['C04.588.274.476.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Polychelated cryogels: hemoglobin adsorption from human blood. | The separation and purification methods are extremely important for the hemoglobin (Hb) which is a crucial biomolecule. The adsorption technique is popular among these methods and the cryogels have been used quite much due to their macropores and interconnected flow channels. In this study, the Hb adsorption onto the C... | ['Adsorption', 'Chelating Agents', 'Copper', 'Cryogels', 'Hemoglobins', 'Humans', 'Polymethacrylic Acids'] | 27,684,101 | [['G01.030', 'G02.020'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D20.280.320.375.500', 'D26.255.165.320.375.187'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.081.069.800', 'D05.750.716.822.111.65... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Intercondylar distal humerus fractures--surgical treatment and results. | INTRODUCTION: Controversy persists concerning the preferred treatment for intercondylar distal humerus fractures. The present study was undertaken to evaluate the clinical results after the surgical treatment of 40 intercondylar distal humerus fractures with an average follow-up of 3.9 years.METHODS: The fractures were... | ['Adolescent', 'Adult', 'Aged', 'Bone Screws', 'Bone Transplantation', 'Female', 'Fibrin Tissue Adhesive', 'Follow-Up Studies', 'Fracture Fixation', 'Fractures, Closed', 'Humans', 'Humeral Fractures', 'Male', 'Middle Aged', 'Range of Motion, Articular', 'Severity of Illness Index', 'Treatment Outcome'] | 15,195,581 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['D12.776.124.270.305'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.555.300'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Validation and Application of the Mass Balance Model To Determine the Effectiveness of Portable Air Purifiers in Removing Ultrafine and Submicrometer Particles in an Apartment. | We validated the use of the mass balance model to determine the effectiveness of portable air purifiers in removing ultrafine (<0.10 ìm) and submicrometer particles (0.10-0.53 ìm) in an apartment. We evaluated two identical portable air purifiers, equipped with high efficiency particulate air filters, for their perform... | ['Air Filters', 'Air Pollution, Indoor', 'Equipment Design', 'Filtration', 'Housing', 'Models, Theoretical', 'Particle Size'] | 26,207,386 | [['E05.196.454.201', 'E07.039'], ['N06.850.460.100.080'], ['E05.320'], ['E05.196.454', 'G01.280', 'G02.263'], ['J03.340', 'N01.224.791.400', 'N06.230.150.360', 'N06.850.505.400.800.400'], ['E05.599'], ['G02.712']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Two bee-pollinated plant species show higher seed production when grown in gardens compared to arable farmland. | BACKGROUND: Insect pollinator abundance, in particular that of bees, has been shown to be high where there is a super-abundance of floral resources; for example in association with mass-flowering crops and also in gardens where flowering plants are often densely planted. Since land management affects pollinator numbers... | ['Animals', 'Bees', 'Ecosystem', 'Lamiaceae', 'Lotus', 'Pollination', 'Seeds'] | 20,668,704 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.387'], ['G16.500.275.157', 'N06.230.124'], ['B01.650.940.800.575.912.250.583.520'], ['B01.650.940.800.575.912.250.401.565'], ['G08.686.784.743', 'G15.776'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Multiple enteric pathogens in a patient with diarrhoea. | A woman who recently arrived in Canada from India developed a febrile, diarrhoeal illness. Stool culture revealed the presence of Salmonella typhi, Campylobacter fetus subspecies jejuni and Shigella flexneri. Concurrent infection with these three pathogens does not appear to have been previously reported. The possibili... | ['Adult', 'Bacterial Infections', 'Campylobacter fetus', 'Diarrhea', 'Female', 'Humans', 'Salmonella typhi', 'Shigella flexneri'] | 3,299,934 | [['M01.060.116'], ['C01.150.252'], ['B03.440.180.325', 'B03.660.150.235.250.500.220'], ['C23.888.821.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.440.450.425.800.200.800', 'B03.660.250.150.710.160.750'], ['B03.440.450.425.850.450', 'B03.660.250.150.730.210']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The linea aspera-pilaster complex as a possible cause of confusion with the 'flame sign': a case report. | The linea aspera is an important osteological feature onto which many muscles insert. Evolutionary as well as individual lifestyle changes can lead to the radiographic appearance of the linea aspera-pilaster complex as the track sign. This rare feature is known to radiologists and anthropologists as a normal roentgen a... | ['Diagnosis, Differential', 'Femur', 'Humans', 'Male', 'Middle Aged', 'Osteitis Deformans', 'Radiography', 'Radionuclide Imaging', 'Thigh'] | 21,088,469 | [['E01.171'], ['A02.835.232.043.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.116.692'], ['E01.370.350.700'], ['E01.370.350.710', 'E01.370.384.730'], ['A01.378.610.750']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Conservative management of the Zollinger-Ellison syndrome. Ectopic gastrin production by an ovarian cystadenoma. | Techniques for evaluating ectopic gastrin production associated with the Zollinger-Ellison syndrome are described. The site of gastrin production in this example was a mucinous cystadenoma of the ovary confirmed by immunoperoxidase localization of gastrin within the ovarian tumor cells and by radioimmunoassay of the tu... | ['Cystadenoma', 'Female', 'Gastrins', 'Hormones, Ectopic', 'Humans', 'Middle Aged', 'Ovarian Neoplasms', 'Ovary', 'Radioimmunoassay', 'Zollinger-Ellison Syndrome'] | 7,365,959 | [['C04.557.470.035.320', 'C04.557.470.590.485'], ['D06.472.317.413', 'D06.472.699.280', 'D12.644.400.320', 'D12.644.548.280', 'D12.776.631.650.320'], ['D06.472.397', 'D23.101.140.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Towards a better quality of life (QoL) for patients with pituitary diseases: results from a focus group study exploring QoL. | PURPOSE: Patients treated for pituitary adenomas generally report a reduced quality of life (QoL). At present, the patient's perspective of QoL has not been fully addressed and this, and further insight in potential determinants of QoL in pituitary diseases is required to design strategies to improve QoL. We aimed to d... | ['Acromegaly', 'Adult', 'Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pituitary Diseases', 'Pituitary Neoplasms', 'Prolactinoma', 'Quality of Life', 'Surveys and Questionnaires'] | 24,682,940 | [['C05.116.132.082', 'C10.228.140.617.738.250.100', 'C19.700.355.179'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.140.617.738', 'C19.700'], ['C04.588.322.609', 'C04.588.614.250.195.885.500.600', 'C10.228.140.211.885.500.600', 'C10.228.140.617.4... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Clinical impact of the early alanine amininotransferase flare during tenofovir monotherapy in treatment-na?ve patients with chronic hepatitis B. | BACKGROUND/AIMS: Little is known about the effect of early flares on response during first-line tenofovir disoproxil fumarate (TDF) treatment for chronic hepatitis B (CHB). The aim of this study was to investigate the incidence and outcome of early alanine aminotransferase (ALT) flare in treatment-naive patients with C... | ['Adult', 'Aged', 'Alanine Transaminase', 'Antiviral Agents', 'DNA, Viral', 'Drug Administration Schedule', 'Female', 'Hepatitis B e Antigens', 'Hepatitis B virus', 'Hepatitis B, Chronic', 'Humans', 'Male', 'Middle Aged', 'Real-Time Polymerase Chain Reaction', 'Tenofovir', 'Treatment Outcome', 'Young Adult'] | 28,479,588 | [['M01.060.116'], ['M01.060.116.100'], ['D08.811.913.477.700.100'], ['D27.505.954.122.388'], ['D13.444.308.568'], ['E02.319.283'], ['D23.050.327.495.500.469'], ['B04.280.375.650.425', 'B04.450.390.650.425'], ['C01.221.250.500.100', 'C01.925.256.430.400.100', 'C01.925.440.435.100', 'C06.552.380.350.100', 'C06.552.380.70... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of ammonia and amino acids on the growth and proteolytic activity of three species of rumen bacteria: Prevotella albensis, Butyrivibrio fibrisolvens, and Streptococcus bovis. | The addition of increasing physiological concentrations of ammonia or amino acids had distinct effects on the growth and proteolytic activity of Streptococcus bovis JB1, Prevotella albensis, and Butyrivibrio fibrisolvens DSM3071. The growth of S. bovis and B. fibrisolvens was enhanced by NH(3) and AA, and that of P. al... | ['Amino Acids', 'Ammonia', 'Animals', 'Caseins', 'Dose-Response Relationship, Drug', 'Glucose', 'Prevotella', 'Rumen', 'Streptococcus bovis', 'Vibrio'] | 10,827,280 | [['D12.125'], ['D01.362.075', 'D01.625.050'], ['B01.050'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['G07.690.773.875', 'G07.690.936.500'], ['D09.947.875.359.448'], ['B03.440.080.094.640', 'B03.440.425.410.194.640'], ['A13.869.804'], ['B03.353.750.737.872.150', 'B03.510.400.800.872.150', 'B03.510.550.737.872.150... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thyroid hormone-dependent gene expression as a biomarker of short-term 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) exposure in European common frog (Rana temporaria) tadpoles. | The effects on thyroid hormone-dependent gene biomarker responses of the persistent organochlorine pesticide metabolite 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) were investigated after exposure of 4-week-old European common frog (Rana temporaria) (stage 36) tadpoles to two (0.001 and 0.01 ppm) DDE concentrati... | ['Animals', 'Biomarkers', 'Dichlorodiphenyl Dichloroethylene', 'Environmental Exposure', 'Gene Expression Regulation', 'Growth Hormone', 'Head', 'Larva', 'Metamorphosis, Biological', 'RNA, Messenger', 'Rana temporaria', 'Tail', 'Thyroid Hormones'] | 17,056,472 | [['B01.050'], ['D23.101'], ['D02.455.526.439.292'], ['N06.850.460.350'], ['G05.308'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['A01.456'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G07.345.500.550'], ['D13.444.735.544'], ['B01.050.150.900.090.180.708.420'], ['A13.895'], ['D06.472.931']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Follow-up study on a susceptibility locus for schizophrenia on chromosome 6q. | Evidence for suggestive linkage to schizophrenia with chromosome 6q markers was previously reported from a two-stage approach. Using nonparametric affected sib pairs (ASP) methods, nominal p-values of 0.00018 and 0.00095 were obtained in the screening (81 ASPs; 63 independent) and the replication (109 ASPs; 87 independ... | ['Chromosomes, Human, Pair 6', 'Female', 'Follow-Up Studies', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Lod Score', 'Male', 'Microsatellite Repeats', 'Models, Statistical', 'Psychotic Disorders', 'Schizophrenia'] | 10,402,499 | [['A11.284.187.520.300.325.330', 'G05.360.162.520.300.325.330'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.348.750'], ['G02.111.570.080.708.800.500', 'G05.360.080.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Molecular Genetics of Sex Identification, Breed Ancestry and Polydactyly in the Norwegian Lundehund Breed. | The Norwegian Lundehund breed of dog has undergone a severe loss of genetic diversity as a result of inbreeding and epizootics of canine distemper. As a consequence, the breed is extremely homogeneous and accurate sex identification is not always possible by standard screening of X-chromosomal loci. To improve our gene... | ['Animals', 'Breeding', 'Dogs', 'Female', 'Genetic Markers', 'Genetic Variation', 'Genotype', 'Homozygote', 'Inbreeding', 'Male', 'Microsatellite Repeats', 'Norway', 'Polydactyly', 'Polymorphism, Single Nucleotide', 'Sequence Analysis, DNA', 'Sex Determination Analysis', 'X Chromosome', 'Y Chromosome'] | 25,994,807 | [['B01.050'], ['E05.820.150', 'G05.090'], ['B01.050.150.900.649.313.750.250.216.200'], ['D23.101.387', 'G05.695.450'], ['G05.365'], ['G05.380'], ['G05.380.554'], ['E05.820.150.520', 'G05.090.403'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500'], ['Z01.542.816.374'], ['C05.660.585.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Hemoglobin alterations of the 13-lined ground squirrel while in various activity states. | 1. Characterization of fetal, winter-hibernating, winter-active, summer-active and summer-induced hibernating hemoglobins of 13-lined ground squirrels (Citellus tridecemlineatus) by isoelectric focusing (IEF) pH 7.0-9.0 indicated that this molecule is extremely responsive to the various activity states of this hibernat... | ['Animals', 'Hemoglobins', 'Hibernation', 'Isoelectric Focusing', 'Sciuridae', 'Seasons'] | 318,302 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Kinetic analysis of the fluorescence reaction of histamine with orthophthalaldehyde. | Histamine reacts with orthophthalaldehyde (OPA) in an alkaline medium to form an unstable fluorescent adduct (Fbase). Acidification of the solution gives a stable adduct (Facid). In order to elucidate the mechanism of this fluorescence reaction, a kinetic study of this reaction was carried out. Although Fbase was belie... | ['Aldehydes', 'Chemical Phenomena', 'Chemistry', 'Histamine', 'Hydrogen-Ion Concentration', 'Kinetics', 'Solutions', 'Spectrometry, Fluorescence', 'o-Phthalaldehyde'] | 3,674,363 | [['D02.047'], ['G02'], ['H01.181'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['D26.776'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['D02.047.750', 'D02.241.223.805.780']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Anticoagulant proteases from western diamondback rattlesnake (Crotalus atrox) venom. | Crotalus atrox venom contains agents that render human fibrinogen and plasma incoagulable by thrombin. To elucidate the mechanism of alteration of fibrinogen clotting function by the venom, four immunochemically different proteases, I, II, III, and IV, were purified from the venom by anion-exchange chromatography and c... | ['Amino Acids', 'Animals', 'Anticoagulants', 'Crotalid Venoms', 'Fibrinogen', 'Humans', 'Kinetics', 'Molecular Weight', 'Peptide Hydrolases', 'Protease Inhibitors', 'Snakes', 'Substrate Specificity', 'Thrombin Time', 'Zinc'] | 6,367,819 | [['D12.125'], ['B01.050'], ['D27.505.954.502.119'], ['D20.888.850.960.200', 'D23.946.833.850.960.200'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['G02.494'], ['D08.811.277.656'], ['D27.505.519.389.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hemophagocytic lymphohistiocytosis associated with precursor B acute lymphoblastic leukemia. | We report a case of a child with precursor-B acute lymphoblastic leukemia (ALL) who experienced refractory thrombocytopenia and massive splenomegaly during standard induction chemotherapy. He was diagnosed with hemophatocytic lymphohistiocytosis (HLH) during induction. Clinical and laboratory evaluation showed no evide... | ['Child', 'Humans', 'Lymphohistiocytosis, Hemophagocytic', 'Male', 'Precursor B-Cell Lymphoblastic Leukemia-Lymphoma'] | 21,298,755 | [['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.604.250.410.575'], ['C04.557.337.428.600.600', 'C15.604.515.560.600.600', 'C20.683.515.528.600.600']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cellular trafficking and photochemical internalization of cell penetrating peptide linked cargo proteins: a dual fluorescent labeling study. | Initial cellular uptake of cell penetrating peptide (CPP) linked macromolecules is usually endosomal, with passage from endosome to cytosol a major limitation to efficient delivery. To gain a better understanding of the passage of the CPP-linked proteins, we studied the uptake and localization of CPP-linked proteins th... | ['Cell Line', 'Cell Tracking', 'Cell-Penetrating Peptides', 'Fluorescence', 'Green Fluorescent Proteins', 'Humans', 'Microscopy, Confocal', 'Photochemistry', 'Recombinant Proteins', 'Rhodamines', 'Staining and Labeling', 'Tissue Distribution'] | 21,405,111 | [['A11.251.210'], ['E01.370.225.500.373', 'E01.370.350.557.500', 'E05.200.500.373', 'E05.242.373'], ['D12.644.098'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['D12.776.532.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.395', 'E05.595.395'], ['H01.181.529.711'], ['D12.776.828'],... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of positive end-expiratory pressure with reverse Trendelenburg position in morbidly obese patients undergoing bariatric surgery: effects on hemodynamics and pulmonary gas exchange. | BACKGROUND: Anesthetized morbidly obese patients often exhibit impaired pulmonary gas exchanges, mostly because of a reduction in functional residual capacity. At present, several approaches are suggested to ventilate these patients.METHODS: The efficiency of positive end-expiratory pressure (PEEP) and reverse Trendele... | ['Adult', 'Anesthesia', 'Biliopancreatic Diversion', 'Female', 'Head-Down Tilt', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Obesity, Morbid', 'Positive-Pressure Respiration', 'Pulmonary Gas Exchange', 'Respiratory Function Tests', 'Respiratory Insufficiency'] | 12,935,363 | [['M01.060.116'], ['E03.155'], ['E04.210.120.086', 'E04.210.169'], ['G11.427.695.300'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654.726.500.700', 'C23.888.144.699.500.500', 'E01.370.600.115.100.160.120.699.500.500', 'G07.100.100.160.120.699.500.500'], ['E02.041.625.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An oral health promotion module for the primary health care nursing course in Acornhoek, South Africa. | The severe personnel shortage in the health professions in most developing communities is well documented. This dearth of health workers and the widespread adoption of the primary health care approach (PHCA), requires that health professionals be trained to understand and effectively utilize the skills offered by other... | ['Curriculum', 'Health Education, Dental', 'Health Promotion', 'Humans', 'Oral Health', 'Program Evaluation', 'Public Health Dentistry', 'Public Health Nursing', 'South Africa', 'Surveys and Questionnaires', 'Teaching'] | 10,528,506 | [['I02.158'], ['I02.233.332.374', 'N02.421.726.407.457', 'N06.890.410'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.400.535'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['H02.163.876.770', 'N06.890'], ['H02.478.676.755'], ['Z01.058.290.175.735'], ['E05.31... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
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