Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Effects of (S)-ketamine on striatal dopamine: a [11C]raclopride PET study of a model psychosis in humans. | Administration of the N-methyl-D-aspartate (NMDA) antagonist S-ketamine in normals produces a psychosis-like syndrome including several positive and negative symptoms of schizophrenic disorders (Abi-Saab WM, D'Souza DC, Moghaddam B, Krystal JH. The NMDA antagonist model for schizophrenia: promise and pitfalls. Pharmaco... | ['Adult', 'Binding, Competitive', 'Caudate Nucleus', 'Corpus Striatum', 'Dopamine Antagonists', 'Double-Blind Method', 'Excitatory Amino Acid Antagonists', 'Humans', 'Ketamine', 'Male', 'Psychoses, Substance-Induced', 'Putamen', 'Raclopride', 'Receptors, Dopamine D2', 'Receptors, N-Methyl-D-Aspartate', 'Tomography, Emi... | 10,696,831 | [['M01.060.116'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A08.186.211.200.885.287.249.487.550.184'], ['A08.186.211.200.885.287.249.487'], ['D27.505.519.625.150.175', 'D27.505.696.577.150.175'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D27.505.519.625.190.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Circadian pattern of acute phase proteins in the saliva of growing pigs. | The circadian rhythm of the acute phase proteins (APPs) haptoglobin (Hp) and C-reactive protein (CRP) was assessed in saliva samples from 18- and 21-week old pigs. Saliva was collected at 07.00, 11.00, 15.00 and 19.00 h on two consecutive days and the Hp and CRP concentrations were quantified using two species-specific... | ['Aging', 'Animals', 'C-Reactive Protein', 'Circadian Rhythm', 'Female', 'Haptoglobins', 'Humans', 'Saliva', 'Swine'] | 23,141,963 | [['G07.345.124'], ['B01.050'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['G07.180.562.190'], ['D12.776.124.050.300', 'D12.776.124.790.106.394', 'D12.776.377.715.085.394', 'D12.776.395.560.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.200.666'], ['B01.050.150.900.649.313.500.880... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Autonomic nervous system reactivity within the valence-arousal affective space: Modulation by sex and age. | In the present study, we examined how sex and age shape cardiovascular, electrodermal, and pupillary reactivity to picture series within the valence-arousal affective space in a sample of 176 healthy younger, middle-aged, and older men and women. Across participants, heart rate (HR) decelerated with increasing self-rep... | ['Adult', 'Affect', 'Age Factors', 'Aged', 'Arousal', 'Autonomic Nervous System', 'Blood Pressure', 'Galvanic Skin Response', 'Heart Rate', 'Humans', 'Middle Aged', 'Pupil', 'Sex Factors', 'Visual Perception', 'Young Adult'] | 27,720,997 | [['M01.060.116'], ['F01.470.047'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['F02.830.104', 'G11.561.035'], ['A08.800.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.796.332', 'F02.830.702.315', 'F04.669.332', 'G07.265.563', 'G13.750.415'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Analysis of composite diets of rural pregnant women and comparison with calculated values. | The composite diets of ninety pregnant women residing in rural areas of Haryana, Northern India, were analysed for protein, fat, calcium, iron, phytic acid, polyphenols, in vitro mineral (calcium, iron) availability and digestibility (in vitro) of starch and protein. The mean daily intakes of calcium and iron were lowe... | ['Biological Availability', 'Calcium, Dietary', 'Diet', 'Dietary Fats', 'Dietary Proteins', 'Digestion', 'Female', 'Flavonoids', 'Food Analysis', 'Humans', 'In Vitro Techniques', 'India', 'Iron, Dietary', 'Minerals', 'Nutrition Policy', 'Phenols', 'Phytic Acid', 'Polymers', 'Polyphenols', 'Pregnancy', 'Rural Health', '... | 11,142,610 | [['G03.787.151', 'G07.690.725.129'], ['D01.146.395'], ['G07.203.650.240'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.650.250', 'G10.261.190'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['E05.362', 'J01.576.423.850.100'], ['B01.050.150.9... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
[Severe exacerbation of chronic renal failure in the course of asymptomatic cystolithiasis]. | There has been reported a case of severe exacerbation of chronic renal failure with bilateral hydronephrosis and urosepsis, which was caused by asymptomatic large urinary bladder stone. Life-threatening symptoms of uraemic syndrome were found, which required temporary hemodialysis treatment. Following removal of the ca... | ['Creatinine', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Radiography', 'Renal Dialysis', 'Treatment Outcome', 'Urinary Bladder Calculi', 'Urinary Tract Infections'] | 16,463,713 | [['D03.383.129.308.207'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630'], ['E01.370.350.700'], ['E02.870.300', 'E02.912.800'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['C12.777.829.720', 'C12.777.967.500.925', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The performance of a glucose-ketone meter in the diagnosis of diabetic ketoacidosis in patients with type 2 diabetes in the emergency room. | BACKGROUND: Diabetic ketoacidosis (DKA) is a serious metabolic complication. One of its precipitating causes is insulin omission. DKA requires early diagnosis and strict glucose control, which increases the use of glucose meters in the Emergency Room (ER). We aimed to determine the performance of a glucose-ketone meter... | ['3-Hydroxybutyric Acid', 'Blood Glucose', 'Diabetes Mellitus, Type 2', 'Diabetic Ketoacidosis', 'Emergency Medical Services', 'Female', 'Glycated Hemoglobin A', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Sensitivity and Specificity', 'Spectrophotometry'] | 20,597,827 | [['D02.241.081.114.937.349', 'D02.241.511.429.349', 'D02.522.585.087', 'D10.251.400.143.781.500'], ['D09.947.875.359.448.500'], ['C18.452.394.750.149', 'C19.246.300'], ['C18.452.076.176.652.500', 'C18.452.394.750.535', 'C19.246.099.812'], ['N02.421.297'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381'... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) associated with a novel C82R mutation in the NOTCH3 gene. | Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare inherited cerebrovascular disease associated with mutations in the NOTCH3 gene on chromosome 19, and represents the most common hereditary stroke disorder. We describe a pedigree, which suffered the classical ... | ['Aged', 'Arginine', 'Brain', 'CADASIL', 'Cysteine', 'Family Health', 'Female', 'Genetic Association Studies', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Mutation', 'Receptor, Notch3', 'Receptors, Notch'] | 25,096,610 | [['M01.060.116.100'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['A08.186.211'], ['C10.228.140.300.150.477.200.100', 'C10.228.140.300.275.249', 'C10.228.140.300.400.203', 'C10.228.140.300.510.200.175', 'C10.228.140.300.775.200.200.100', 'C10.228.140.380.230.124', 'C14.907.253.092.477.200.100', 'C14.907... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Corpus callosotomy for epilepsy. I. Seizure effects. | Twenty-two patients were analyzed 2 or more years after corpus callosum section (9 partial, 13 total). Forty-one percent had class 1 outcome (elimination of secondarily generalized and complex partial seizures), 32% had class 2 outcome (elimination of secondarily generalized seizures), and 27% had class 3 outcome (no a... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Corpus Callosum', 'Electroencephalography', 'Epilepsies, Partial', 'Epilepsy', 'Epilepsy, Temporal Lobe', 'Female', 'Humans', 'Male', 'Tomography, X-Ray Computed'] | 3,122,070 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['A08.186.211.200.885.800.750'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.360'], ['C10.228.140.490'], ['C10.228.140.490.360.290', 'C10.228.140.490.493.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.350.810',... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Phosphorylation of RhoB by CK1 impedes actin stress fiber organization and epidermal growth factor receptor stabilization. | RhoB is a small GTPase implicated in cytoskeletal organization, EGF receptor trafficking and cell transformation. It is an immediate-early gene, regulated at many levels of its biosynthetic pathway. Herein we show that the serine/threonine protein kinase CK1 phosphorylates RhoB in vitro but not RhoA or RhoC. With the u... | ['Actin Cytoskeleton', 'Actins', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Casein Kinase Ialpha', 'Enzyme Activation', 'Enzyme Inhibitors', 'ErbB Receptors', 'HeLa Cells', 'Humans', 'Molecular Sequence Data', 'Phosphorylation', 'Protein Processing, Post-Translational', 'Protein-Serine-Threonine Kinases', 'Sequ... | 18,590,726 | [['A11.284.430.214.190.750.050'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['D05.500.117.750.100', 'D08.811.913.696.620.682.700.140.300.100', 'D12.776.476.081.750.100', 'D12.776.476.150.299.100'], ['G02.111... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Assessing Patient Preferences for Intestinal Failure Management Using the Time Trade-Off Methodology. | BACKGROUND: There are limited management options available for people with Type III intestinal failure (IF), with home parenteral nutrition (HPN) being the main treatment option. The aim of this research is to compare patient preferences in managing Type III IF using time trade-off (TTO) methodology and to determine wh... | ['Activities of Daily Living', 'Adult', 'Aged', 'Australia', 'Cohort Studies', 'Cross-Sectional Studies', 'Disease Management', 'Female', 'Gastrointestinal Agents', 'Health Services Accessibility', 'Humans', 'Intestinal Diseases', 'Intestine, Small', 'Intestines', 'Male', 'Middle Aged', 'Organ Transplantation', 'Parent... | 30,714,625 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['M01.060.116.100'], ['Z01.639.100', 'Z01.678.100.373'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N04.590.607... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Humanities [K]... | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Risk factors for 28-day mortality in elderly patients with extended-spectrum â-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae bacteremia. | Gram-negative bacteremia is common in elderly patients and, compared with younger patients, mortality rates in bacteremic elderly patients are high. ESBL-producing organisms were one of the most important risk factors associated with mortality. In addition, older age is one of risk factors for colonization or infection... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Bacteremia', 'Escherichia coli', 'Escherichia coli Infections', 'Female', 'Follow-Up Studies', 'Geriatric Assessment', 'Humans', 'Klebsiella Infections', 'Klebsiella pneumoniae', 'Male', 'Republic of Korea', 'Retrospective Studies', 'Risk Factors', 'Survival Rate', 'Time Fa... | 23,988,261 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.3... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Evaluation of results of thymectomy in myasthenia gravis. | The results of thymectomy carried out in 150 cases of myasthenia gravis are discussed. In a group of 123 cases followed for 1 to 5 years after the operation, full remission was observed in 24.4% of cases, significant improvement in 36.6%, slight improvement in 24.4% and no improvement in 8.1%, while deterioration occur... | ['Adolescent', 'Adult', 'Child', 'Cholinesterase Inhibitors', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Myasthenia Gravis', 'Remission, Spontaneous', 'Thymectomy', 'Thymus Hyperplasia', 'Thymus Neoplasms', 'Time Factors'] | 55,471 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.614.550.500', 'C04... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Securing the Airway in Pretracheal Dermal Metastases From Oropharyngeal Carcinoma: A Case Report. | Dermal metastases reflect the ominous and aggressive spread of oropharyngeal squamous cell carcinomas. The rampant proliferation of these metastatic tumors to the neck results in respiratory distress and impending airway obstruction. We report a case of a patient with massive neck dermal metastases requiring urgent air... | ['Adult', 'Carcinoma, Squamous Cell', 'Fiber Optic Technology', 'Humans', 'Intubation, Intratracheal', 'Male', 'Neck', 'Oropharyngeal Neoplasms', 'Skin Neoplasms'] | 29,688,927 | [['M01.060.116'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['H01.671.617.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['A01.598'], ['C04.588.443.665.710.684', 'C07.550.745.671', 'C09.647.710.685', 'C09.775.549.685'], ['C04.588.805', 'C17.800.882']] | ['Named Groups [M]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Structural limits for evolutive capacities in complex molecular systems. | The possibilities of evolution for a system with and without a code of translation from nucleic acids into proteins are evaluated. Our interest is mainly centred on the enzymatic RNA case since this molecule has, at the same time, reproductive and functional properties. After scanning the evolutive capacities of the en... | ['Biological Evolution', 'Enzymes', 'Genetic Code', 'Ligases', 'Molecular Biology', 'Protein Biosynthesis', 'RNA', 'RNA, Catalytic'] | 1,707,552 | [['G05.045', 'G16.075'], ['D08.811'], ['G05.360.335'], ['D08.811.464'], ['H01.158.201.636', 'H01.158.273.343.595', 'H01.181.122.650'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['D13.444.735'], ['D08.811.797', 'D13.444.735.790.199']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The genetic animal model of reflex epilepsy in the Mongolian gerbil: differential efficacy of new anticonvulsive drugs and prototype antiepileptics. | Four new anticonvulsive drugs were compared to four prototype antiepileptics regarding their differential efficacy, i.e. against tonic-clonic, myoclonic, and minor seizures, in reflex epilepsy in genetically epileptic gerbils. We distinguished at least three types of drugs: Phenytoin and ralitoline selectively prevente... | ['Animals', 'Anticonvulsants', 'Disease Models, Animal', 'Electroshock', 'Female', 'Gerbillinae', 'Male', 'Models, Genetic', 'Seizures'] | 3,659,116 | [['B01.050'], ['D27.505.954.427.080'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.723.402.403', 'F04.669.224'], ['B01.050.150.900.649.313.992.635.300'], ['E05.599.395.397'], ['C10.597.742', 'C23.888.592.742']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Incidence and outcomes of unstable angina compared with non-ST-elevation myocardial infarction. | OBJECTIVE: Assess the relative incidence and compare characteristics and outcome of unstable angina (UA) and non-ST-elevation myocardial infarction (NSTEMI).DESIGN: Two independent prospective multicentre diagnostic studies (Advantageous Predictors of Acute Coronary Syndromes Evaluation [APACE] and High-Sensitivity Tro... | ['Aged', 'Aged, 80 and over', 'Angina, Unstable', 'Biomarkers', 'Cause of Death', 'Disease Progression', 'Europe', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Non-ST Elevated Myocardial Infarction', 'Prognosis', 'Prospective Studies', 'Risk Assessment', 'Risk Factors', 'Time Factors', 'Troponin'] | 31,018,955 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.647.187.150', 'C14.907.585.187.150', 'C23.888.592.612.233.500.150'], ['D23.101'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['C23.550.291.656'], ['Z01.542'], ['B01.050.150.900.649.313.988.400... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Release of prostaglandin F1alpha and F2alpha from superfused platelets: quantitative evaluation of the inhibitory effects of some aspirin-like drugs. | The release of PGF1alpha and PGF2alpha from superfused blood platelets was studied by the combined use of two radioimmunoassay systems with different specificities. PGF1alpha only accounted for approximately 30% of the total immunoreactivity. A substantially similar pattern of release was obtained with platelets of rat... | ['Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Blood Platelets', 'Depression, Chemical', 'Diethylamines', 'Fenoprofen', 'Humans', 'Hydrocortisone', 'Indomethacin', 'Male', 'Oxazoles', 'Perfusion', 'Prostaglandins F', 'Radioimmunoassay', 'Rats', 'Time Factors'] | 1,080,283 | [['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['A11.118.188', 'A15.145.229.188'], ['G07.690.773.750'], ['D02.092.471.302'], ['D02.241.223.701.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of the herbicide bentazon on soil microbial community. | Changes in microbial numbers and activities in a soil in response to bentazon applied at 10 and 100 ppm were studied after 4 and 30 weeks of incubation in laboratory conditions. As regards the eight general and functional microbial groups studied (aerobic and anaerobic bacteria, fungi, aerobic and anaerobic N2-fixing b... | ['Bacteria', 'Benzothiadiazines', 'Biodegradation, Environmental', 'Fungi', 'Herbicides', 'Soil Microbiology'] | 8,857,270 | [['B03'], ['D02.886.590.700.135', 'D02.886.655.500', 'D03.633.100.174'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['B01.300'], ['D27.720.031.700.366', 'D27.888.723.366'], ['H01.158.273.540.274.555', 'N06.850.425.300']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of external electromagnetic fields on the conformational sampling of a short alanine peptide. | Non-equilibrium molecular dynamics simulations of a solvated 21-residue polyalanine (A21) peptide, featuring a high propensity for helix formation, have been performed at 300 K and 1 bar in the presence of external electromagnetic (e/m) fields in the microwave region (2.45 GHz) and an r.m.s. electric field intensity ra... | ['Electromagnetic Fields', 'Entropy', 'Hydrogen Bonding', 'Peptides', 'Protein Folding', 'Protein Structure, Secondary'] | 22,328,143 | [['G01.358.500.260', 'G01.358.750.500'], ['G01.906.345'], ['G02.282'], ['D12.644'], ['G01.154.651', 'G02.111.688'], ['G02.111.570.820.709.600']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Systematic analysis of viral genes responsible for differential virulence between American and Australian West Nile virus strains. | A variant Australian West Nile virus (WNV) strain, WNVNSW2011, emerged in 2011 causing an unprecedented outbreak of encephalitis in horses in south-eastern Australia. However, no human cases associated with this strain have yet been reported. Studies using mouse models for WNV pathogenesis showed that WNVNSW2011 was le... | ['Animals', 'Australia', 'Disease Models, Animal', 'Genes, Viral', 'Genetic Complementation Test', 'Horses', 'Humans', 'Immune Evasion', 'Interferon Type I', 'Mice', 'Recombination, Genetic', 'United States', 'Viral Nonstructural Proteins', 'Virulence', 'Virus Replication', 'West Nile Fever', 'West Nile virus'] | 25,626,681 | [['B01.050'], ['Z01.639.100', 'Z01.678.100.373'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['E05.393.281.526'], ['B01.050.150.900.649.313.984.235.472'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.462.400', 'G12.413'... | ['Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Epidermal change can alter mechanical properties of hairless mouse skin topically treated with 1alpha, 25-dihydroxyvitamin D(3). | Wrinkle formation caused by photoaging clearly involves changes of extracellular matrix components and mechanical properties of the skin. Recently, it was reported that the topical application of 1alpha, 25-dihydroxyvitamin D(3) to hairless mouse skin induced wrinkling. Here we have evaluated the effect of topical appl... | ['Administration, Topical', 'Animals', 'Calcitriol', 'Dermis', 'Dose-Response Relationship, Drug', 'Elasticity', 'Epidermis', 'Mice', 'Mice, Hairless', 'Skin', 'Skin Aging', 'Viscosity'] | 11,064,245 | [['E02.319.267.120'], ['B01.050'], ['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.938.146.478.387.300'], ['A17.815.180'], ['G07.690.773.875', 'G07.690.936.500'], ['G01.374.590'], ['A10.272.497', 'A17.815.250'], ['B01.050.150.900.649.313.992... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Turtle lymphocyte surface antigens in chelydra serpentina as characterized by rabbit anti-turtle thymocyte sera. | Spleen and thymus suspensions from the turtle, Chelydra serpentina were examined by indirect immunofluorescence with a rabbit anti-turtle thymocyte serum (RATT). After the species-specific antibodies had been absorbed out, the antisera labeled all lymphocytes in the thymus and spleen. The specificity of RATT for thymoc... | ['Animals', 'Antigens, Surface', 'Lymphocytes', 'Male', 'Rabbits', 'Spleen', 'Thymus Gland', 'Turtles'] | 6,734,872 | [['B01.050'], ['D23.050.301'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['B01.050.150.900.649.313.968.700'], ['A10.549.700', 'A15.382.520.604.700'], ['A10.549.750', 'A15.382.520.604.750'], ['B01.050.150.900.833.848']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A new step toward the artificial ovary: survival and proliferation of isolated murine follicles after autologous transplantation in a fibrin scaffold. | OBJECTIVE: To create an artificial ovary to provide an alternative way of restoring fertility in patients who cannot benefit from transplantation of cryopreserved ovarian tissue due to the threat of reintroducing malignant cells.DESIGN: In vivo experimental study.SETTING: Gynecology research unit in a university hospit... | ['Animals', 'Bioartificial Organs', 'Cell Proliferation', 'Cell Survival', 'Cells, Cultured', 'Equipment Design', 'Equipment Failure Analysis', 'Female', 'Fibrin', 'Mice', 'Ovarian Follicle', 'Ovary', 'Tissue Scaffolds'] | 24,462,059 | [['B01.050'], ['E07.858.082.212'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['A11.251'], ['E05.320'], ['E05.325.192'], ['D12.776.124.270'], ['B01.050.150.900.649.313.992.635.505.500'], ['A05.360.319.114.630.535', 'A06.300.312.497.535'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['E07.20... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of UDP-galactose: lactose (lactosylceramide) alpha-4 and beta-3 galactosyltransferases in human kidney. | Two galactosyltransferases were identified in human kidney microsomes which both transfer galactose from UDP Gal to lactose as well as to lactosylceramide. Using a solubilized and a partially purified enzyme preparation sufficient product could be obtained for detailed structural analysis. The trisaccharide products we... | ['Antigens, CD', 'Blood Group Antigens', 'Galactosyltransferases', 'Glycosphingolipids', 'Humans', 'Kidney', 'Lactose', 'Lactosylceramides', 'Microsomes', 'P Blood-Group System', 'Uridine Diphosphate Galactose'] | 3,099,784 | [['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.290', 'D23.050.705.230'], ['D08.811.913.400.450.400'], ['D09.400.410.420', 'D10.390.470', 'D10.570.877.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['D09.698.629.305.340', 'D09.947.750.340'], ['D02.065.313.612', 'D09.400.410.420.525.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elimination kinetic model for organic chemicals in earthworms. | Mechanistic understanding of bioaccumulation in different organisms and environments should take into account the influence of organism and chemical depending factors on the uptake and elimination kinetics of chemicals. Lipophilicity, metabolism, sorption (bioavailability) and biodegradation of chemicals are among the ... | ['Animals', 'Kinetics', 'Models, Chemical', 'Oligochaeta', 'Organic Chemicals', 'Polycyclic Aromatic Hydrocarbons', 'Soil Pollutants'] | 20,185,163 | [['B01.050'], ['G01.374.661', 'G02.111.490'], ['E05.599.495'], ['B01.050.500.091.657'], ['D02'], ['D02.455.426.559.847', 'D04.615'], ['D27.888.284.756']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Conservative management of a ruptured gastrocnemius muscle in a male llama. | Rupture of the gastrocnemius muscle was diagnosed in an obese llama using physical examination and ultrasound imaging. Conservative therapy consisting of the use of a cast to immobilize the affected limb permitted the muscle to heal. Only mild, residual gait abnormalities were observed on follow-up examination. | ['Animals', 'Camelids, New World', 'Casts, Surgical', 'Male', 'Muscle, Skeletal', 'Rupture'] | 9,818,139 | [['B01.050'], ['B01.050.150.900.649.313.500.190.090'], ['E07.858.442.660.430.500', 'E07.858.690.725.430.500'], ['A02.633.567', 'A10.690.552.500'], ['C26.761']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Arrhythmias during the acute phase of reperfusion therapy for acute myocardial infarction: effects of beta-adrenergic blockade. | In 107 patients with acute myocardial infarction, the incidence of ventricular arrhythmias during the acute phase of thrombolysis was examined by means of Holter monitoring. In patients with a patient infarct-related artery as assessed angiographically at 90 minutes, the occurrence of accelerated idioventricular rhythm... | ['Adrenergic beta-Antagonists', 'Aged', 'Aged, 80 and over', 'Arrhythmias, Cardiac', 'Female', 'Humans', 'Injections, Intravenous', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Myocardial Reperfusion'] | 1,350,703 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.067', 'C23.550.073'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Generation of composite dose and biological effective dose (BED) over multiple treatment modalities and multistage planning using deformable image registration. | Currently there are no commercially available tools to generate composite plans across different treatment modalities and/or different planning image sets. Without a composite plan, it may be difficult to perform a meaningful dosimetric evaluation of the overall treatment course. In this paper, we introduce a method to... | ['Carcinoma, Non-Small-Cell Lung', 'Combined Modality Therapy', 'Humans', 'Lung Neoplasms', 'Male', 'Prostatic Neoplasms', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy, Conformal', 'Tomography, X-Ray Computed', 'Tumor Burden'] | 19,931,027 | [['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E02.815.639'], ['E02.950.825', ... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Pelecitus tercostatus (Molin, 1960) (Nematoda, Onchocercidae) in Amazona vinacea (Aves, Psittaciformes) from Argentina: morphological details and clinical findings. | Pelecitus tercostatus (Molin, 1860) (Onchocercidae, Dirofilariinae) was found in the leg of a Vinaceous-breasted Parrot Amazona vinacea (Aves, Psittaciformes) from Misiones, Argentina. The present report enlarges the host distribution of the species and represents the first record of any nematode in A. vinacea. The mac... | ['Amazona', 'Animals', 'Argentina', 'Bird Diseases', 'Nematoda', 'Nematode Infections'] | 22,807,057 | [['B01.050.150.900.248.710.672.050'], ['B01.050'], ['Z01.107.757.077'], ['C22.131'], ['B01.050.500.500.294'], ['C01.610.335.508']] | ['Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Paraffinoma, siliconoma and Co: Disastrous consequences of failed penile augmentation-A single-centre successful surgical management of a challenging entity. | The purpose of this study was to present our series of patients with disastrous consequences of failed penile self-augmentation and suggested surgical reconstruction. Ten patients with median age of 23 years and a variety of penile and scrotal deformities due to injections of several substances had undergone successful... | ['Adult', 'Erectile Dysfunction', 'Granuloma, Foreign-Body', 'Humans', 'Injections, Subcutaneous', 'Male', 'Oils', 'Olive Oil', 'Organ Size', 'Paraffin', 'Penile Diseases', 'Penis', 'Petrolatum', 'Reconstructive Surgical Procedures', 'Scrotum', 'Silicones', 'Treatment Outcome', 'Urologic Surgical Procedures, Male', 'Yo... | 29,993,129 | [['M01.060.116'], ['C12.294.644.486', 'F03.835.400'], ['C23.550.382.437', 'C26.392.560.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.620'], ['D10.627'], ['D10.212.302.380.580', 'D10.212.507.650', 'D10.627.700.728', 'G07.203.300.375.400.500', 'J02.500.375.400.500'], ['E01.370.600.115.100.660'... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Microvascular caliber changes in intramucosal and submucosally invasive esophageal cancer. | BACKGROUND AND STUDY AIM: Intrapapillary capillary loops (IPCLs) show distinct pattern changes corresponding to tumor progression and depth of invasion, important for in vivo characterization of superficial squamous cell carcinoma (SCC). We examined the relation between invasion depth and histopathologic IPCL diameter.... | ['Aged', 'Capillaries', 'Carcinoma, Squamous Cell', 'Esophageal Neoplasms', 'Esophagoscopy', 'Esophagus', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mucous Membrane', 'Neoplasm Invasiveness', 'Prospective Studies'] | 23,801,316 | [['M01.060.116.100'], ['A07.015.461.165'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E01.370.372.250.250.275', 'E01.370.388.250.250.250.260', 'E04.210.240.250.260', 'E04.502.250.250.250.260'], ['A03.556.875.500'... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Safety, Tolerability, and Pharmacodynamics of Intrathecal Injection of Recombinant Human HGF (KP-100) in Subjects With Amyotrophic Lateral Sclerosis: A Phase I Trial. | Hepatocyte growth factor is an endogenous pleiotropic factor shown to act as a potent neuroprotectant against disease progression in animal models of amyotrophic lateral sclerosis, which is a devastating, adult-onset motor neuron disease. To evaluate the safety, tolerability, and pharmacokinetics of recombinant 5-resid... | ['Adult', 'Amyotrophic Lateral Sclerosis', 'Disease Progression', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Female', 'Hepatocyte Growth Factor', 'Humans', 'Injections, Spinal', 'Male', 'Middle Aged', 'Recombinant Proteins'] | 30,536,581 | [['M01.060.116'], ['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['C23.550.291.656'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['D12.644.276.374.420', 'D12.776.467.374.420', 'D23.529.374.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.3... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Detection of methicillin-resistant Staphylococcus aureus (MRSA) carrying the mecC gene in wild small mammals in Spain. | OBJECTIVES: To determine the rate of Staphylococcus aureus faecal carriage in 101 wild small mammals in Spain and to characterize the isolates obtained.METHODS: Faecal samples were seeded on mannitol salt agar and ORSAB plates. The presence of the resistance genes mecA, mecC and blaZ and the new blaZ allotype associate... | ['Animals', 'Animals, Wild', 'Bacterial Typing Techniques', 'DNA, Bacterial', 'Feces', 'Methicillin-Resistant Staphylococcus aureus', 'Mice', 'Microbial Sensitivity Tests', 'Molecular Typing', 'Myoxidae', 'Penicillin-Binding Proteins', 'Rats', 'Shrews', 'Spain', 'Virulence Factors', 'beta-Lactamases'] | 24,710,026 | [['B01.050'], ['B01.050.050.300'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['D13.444.308.212'], ['A12.459'], ['B03.300.390.400.800.750.100.500', 'B03.353.500.750.750.100.500', 'B03.510.100.750.750.100.500', 'B03.510.400.790.750.100.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.225.875.595', ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Quantitative computed tomography (QCT) of the forearm using general purpose spiral whole-body CT scanners: accuracy, precision and comparison with dual-energy X-ray absorptiometry (DXA). | BACKGROUND: Dual-energy X-ray absorptiometry (DXA) allows clinically relevant measurement of bone mineral density (BMD) at central and appendicular skeletal sites, but DXA has a limited ability to assess bone geometry and cannot distinguish between the cortical and trabecular bone compartments. Quantitative computed to... | ['Absorptiometry, Photon', 'Aged', 'Aged, 80 and over', 'Female', 'Forearm', 'Humans', 'Middle Aged', 'Phantoms, Imaging', 'Postmenopause', 'Sensitivity and Specificity', 'Tomography Scanners, X-Ray Computed', 'Tomography, X-Ray Computed', 'Ulna', 'Whole Body Imaging'] | 19,345,291 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A01.378.800.585'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.671'], ['G08.686.157.500.625', 'G08.686.841.249.500.625'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.70... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Role of adenoid biofilm in chronic otitis media with effusion in children. | To study the extent of surface adenoid biofilm and to evaluate its role in the pathogenesis of chronic otitis media with effusion (COME) in children. The study was carried out on 100 children between 3 and 14 years of age, who were divided into two groups. The first group (50 children) had otitis media with effusion as... | ['Adenoidectomy', 'Adenoids', 'Adolescent', 'Biofilms', 'Child', 'Child, Preschool', 'Chronic Disease', 'Ear, Middle', 'Female', 'Humans', 'Hypertrophy', 'Male', 'Microscopy, Electron, Scanning', 'Otitis Media', 'Otitis Media with Effusion', 'Polymerase Chain Reaction', 'Sleep Apnea, Obstructive', 'Tissue Culture Techn... | 23,179,928 | [['E04.580.068'], ['A04.623.557.500', 'A10.549.100', 'A14.724.557.500', 'A15.382.520.604.100'], ['M01.060.057'], ['A20.593', 'G06.120'], ['M01.060.406'], ['M01.060.406.448'], ['C23.550.291.500'], ['A09.246.397'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.775'], ['E01.370.350.515.402.541', 'E05.595.402.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Confirming urinary excretion of mephentermine and phentermine following the ingestion of oxethazaine by gas chromatography-mass spectrometry analysis. | Mephentermine and phentermine, substances prohibited in sports by the World Anti-Doping Agency, were found for the first time in urine specimens following the administration of a therapeutic medication, oxethazaine. In a recent sporting event, a urine specimen donor who tested positive for mephentermine and phentermine... | ['Acetic Anhydrides', 'Adult', 'Anesthetics, Local', 'Calibration', 'Doping in Sports', 'Ethanolamines', 'Female', 'Fluoroacetates', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Male', 'Mephentermine', 'Phentermine', 'Reproducibility of Results', 'Substance Abuse Detection', 'Trifluoroacetic Acid'] | 20,223,098 | [['D02.113.075', 'D02.241.081.018.193'], ['M01.060.116'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['E05.978.155'], ['I01.880.735.265'], ['D02.033.100.291', 'D02.033.375.291', 'D02.092.063.291'], ['D02.241.081.018.285', 'D02.455.526.510.286'], ['E05.196.181.349.500', 'E05.1... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Epidemiology of human hydatidosis in the Province of R?o Negro, Argentina]. | The number of human cases with hydatidosis in the Province de R?o Negro in the period 1969-1983 was determined by a retrospective exam of the registers at the Provincial Ministry of Health. From 1216 cases the yearly numbers between 59.4 in 1969-78 and 124.4 cases between 1979-83. This implies a yearly of 3.24 X 10,000... | ['Adult', 'Argentina', 'Child', 'Child, Preschool', 'Echinococcosis', 'Echinococcosis, Hepatic', 'Echinococcosis, Pulmonary', 'Female', 'Humans', 'Male', 'Retrospective Studies', 'Serologic Tests'] | 3,577,624 | [['M01.060.116'], ['Z01.107.757.077'], ['M01.060.406'], ['M01.060.406.448'], ['C01.610.335.190.396'], ['C01.610.335.190.396.314', 'C01.610.518.314', 'C06.552.664.272'], ['C01.610.335.190.396.480', 'C01.610.582.314', 'C01.748.450.314', 'C08.381.517.314', 'C08.730.450.314'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cerebello-thalamo-cortical projections to the posterior parietal cortex in the macaque monkey. | The cerebello-thalamo-posterior parietal cortical projections were investigated electrophysiologically and morphologically in macaque monkeys. In anesthetized monkeys, electrical stimulation of every cerebellar nucleus evoked marked surface-positive, depth-negative (s-P, d-N) cortical field potentials in the superior p... | ['Animals', 'Axonal Transport', 'Brain Mapping', 'Cerebellar Nuclei', 'Electric Stimulation', 'Evoked Potentials', 'Fluorescent Dyes', 'Macaca', 'Neural Pathways', 'Neurons', 'Parietal Lobe', 'Thalamus', 'Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate'] | 11,489,539 | [['B01.050'], ['G03.143.355.040', 'G04.392.040', 'G11.561.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.132.810.428.200.337'], ['E05.723.402'], ['G07.265.216.500', 'G11.561.200.500'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.988.400.112.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Plaque distribution of stenotic middle cerebral artery and its clinical relevance. | BACKGROUND AND PURPOSE: Microanatomy studies reveal that most penetrating branches of middle cerebral artery (MCA) arise from the dorsal-superior surface of the trunk. Using high-resolution MRI, we sought to explore the plaque distribution of MCA atherosclerosis and its clinical relevance in relation to the orifices of... | ['Atherosclerosis', 'Humans', 'Intracranial Arteriosclerosis', 'Magnetic Resonance Imaging', 'Middle Cerebral Artery', 'Plaque, Atherosclerotic', 'Retrospective Studies'] | 21,799,160 | [['C14.907.137.126.307'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.510.800', 'C14.907.137.126.372', 'C14.907.253.560.350'], ['E01.370.350.825.500'], ['A07.015.114.228.550'], ['C23.300.823'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
DiGalactosyl-Glycero-Ether Lipid: synthetic approaches and evaluation as SK3 channel inhibitor. | The recent discoveries of the involvement of SK3 channel in some cell motility mechanisms occurring in cancer disease have opened up the way to the synthesis of inhibitors that could reduce metastasis formation. On the basis of our recent previous works showing that both lactose-glycero-ether lipid (Ohmline) and some p... | ['Cell Movement', 'Glycolipids', 'HEK293 Cells', 'Humans', 'Small-Conductance Calcium-Activated Potassium Channels'] | 23,715,410 | [['G04.198', 'G07.568.500.180'], ['D09.400.410', 'D10.390'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.530.400.600.150.750', 'D12.776.543.550.450.750.150.750', 'D12.776.543.585.400.750.150.750']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Noncovalent mass spectrometry for the characterization of antibody/antigen complexes. | Monoclonal antibodies (mAbs) have taken on an increasing importance for the treatment of various diseases including cancers, immunological disorders, and other pathologies. These large biomolecules display specific structural features, which affect their efficiency and need therefore to be extensively characterized usi... | ['Animals', 'Antibodies, Monoclonal', 'Antigen-Antibody Complex', 'Buffers', 'CHO Cells', 'Cricetinae', 'Humans', 'Hybridomas', 'Immunoglobulin G', 'Spectrometry, Mass, Electrospray Ionization'] | 23,475,725 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['D27.720.470.280'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anopheles gambiae laminin interacts with the P25 surface protein of Plasmodium berghei ookinetes. | Laminin is a major constituent of the basal lamina surrounding the midgut of the malaria vectors that has been implicated in the development of the Plasmodium oocyst. In this report we describe the cloning of the Anopheles gambiae gene encoding the laminin gamma 1 polypeptide and follow its expression during mosquito d... | ['Amino Acid Sequence', 'Animals', 'Anopheles', 'Dimerization', 'Gene Expression Regulation, Developmental', 'Insect Proteins', 'Laminin', 'Malaria', 'Molecular Sequence Data', 'Molecular Weight', 'Plasmodium berghei', 'Protein Binding', 'Protozoan Proteins', 'Two-Hybrid System Techniques'] | 11,223,130 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['G02.206', 'G03.230'], ['G05.308.310'], ['D12.776.093.500'], ['D12.776.395.550.530', 'D12.776.543.550.500', 'D12.776.860.300.675'], ['C01.610.752.530', 'C01.920.875'], ['L01.453.245.667'], ['G02.494'], ['... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The 13C chemical-shift index: a simple method for the identification of protein secondary structure using 13C chemical-shift data. | A simple technique for identifying protein secondary structures through the analysis of backbone 13C chemical shifts is described. It is based on the Chemical-Shift Index [Wishart et al. (1992) Biochemistry, 31, 1647-1651] which was originally developed for the analysis of 1H(alpha) chemical shifts. By extending the Ch... | ['Amino Acids', 'Carbon Isotopes', 'Interferon-gamma', 'Magnetic Resonance Spectroscopy', 'Protein Structure, Secondary', 'Solvents'] | 8,019,132 | [['D12.125'], ['D01.268.150.075', 'D01.496.123'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615.350'], ['E05.196.867.519'], ['G02.111.570.820.709.600'], ['D27.720.844']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alignment efficiency and discomfort of three orthodontic archwire sequences: a randomized clinical trial. | AIM: To compare the efficiency of orthodontic archwire sequences produced by three manufacturers.DESIGN: Prospective, randomized clinical trial with three parallel groups.SETTING: Private orthodontic practice in Caloundra, QLD, Australia.SUBJECTS AND METHODS: One hundred and thirty-two consecutive patients were randomi... | ['Adolescent', 'Alloys', 'Dental Alloys', 'Dental Arch', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Malocclusion', 'Mandible', 'Nickel', 'Orthodontic Appliance Design', 'Orthodontic Wires', 'Pain Measurement', 'Prospective Studies', 'Single-Blind Method', 'Stainless Steel', 'Time Factors', 'Titanium', 'Tooth Mov... | 21,367,826 | [['M01.060.057'], ['D01.552.033', 'D25.058', 'J01.637.051.058'], ['D25.339.208', 'J01.637.051.339.208'], ['A02.835.232.781.324.502.320', 'A14.521.320'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.793.494'], ['A02.835.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Multinomial Logistic Model for Coinfection Diagnosis Between Arbovirus and Malaria in Kedougou. | In tropical regions, populations continue to suffer morbidity and mortality from malaria and arboviral diseases. In Kedougou (Senegal), these illnesses are all endemic due to the climate and its geographical position. The co-circulation of malaria parasites and arboviruses can explain the observation of coinfected case... | ['Antibodies, Viral', 'Arbovirus Infections', 'Biostatistics', 'Coinfection', 'Computer Simulation', 'Databases, Factual', 'Female', 'Humans', 'Immunoglobulin M', 'Logistic Models', 'Malaria', 'Male', 'Plasmodium', 'Predictive Value of Tests', 'Senegal'] | 31,461,403 | [['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['C01.920.500', 'C01.925.081'], ['E05.318.740.237'], ['C01.218'], ['L01.224.160'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.574', 'D12... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Placental intravillous accumulation of sulfated mucosubstances. A reevaluation of so-called hydropic degeneration of villi. | A histochemical study was performed on 46 placentas showing so-called hydropic degeneration of villi. The 46 cases included early abortuses (35 cases), incomplete moles (four cases), and complete hydatidiform moles (seven cases). All the specimens showed diffuse, positive staining of the distended villous stroma with a... | ['Abortion, Spontaneous', 'Adult', 'Alcian Blue', 'Body Water', 'Chorionic Villi', 'Female', 'Glycosaminoglycans', 'Histocytochemistry', 'Humans', 'Hydatidiform Mole', 'Hydrogen-Ion Concentration', 'Middle Aged', 'Pregnancy', 'Staining and Labeling', 'Sulfates'] | 1,380,222 | [['C13.703.039', 'G08.686.784.769.496.125'], ['M01.060.116'], ['D03.633.100.473.050'], ['A12.207.200'], ['A10.615.284.473.200', 'A16.254.750.473.200', 'A16.710.189'], ['D09.698.373'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Agreement between parents and teachers on behavioral/emotional problems in Japanese school children using the child behavior checklist. | We investigated the agreement between Japanese parents' and teachers' ratings concerning their children's behavioral/emotional problems. Mothers (n = 276) and teachers (n = 19) assessed each child (n = 316; 6 to 12 years old ) using Japanese parent and teacher version of the Child Behavior Checklist. Parent-teacher agr... | ['Child', 'Child Behavior Disorders', 'Cooperative Behavior', 'Faculty', 'Female', 'Humans', 'Japan', 'Male', 'Mood Disorders', 'Parents', 'Surveys and Questionnaires'] | 14,617,945 | [['M01.060.406'], ['F03.625.141'], ['F01.145.813.115'], ['M01.526.702.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['F03.600'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Risk factors for mortality in young children living under various socio-economic conditions in Lahore, Pakistan: with particular reference to inbreeding. | Risk factors such as maternal age, parity, previous siblings' death, inbreeding of parents, birth weight, birth length were examined in a population-based prospective study in four population groups at different levels of urbanization in and round Lahore, Pakistan. From September 1984 to March 1995, 2967 full-term, sin... | ['Adolescent', 'Adult', 'Consanguinity', 'Female', 'Humans', 'Infant Mortality', 'Infant, Newborn', 'Male', 'Pakistan', 'Risk Factors', 'Social Class'] | 9,842,997 | [['M01.060.057'], ['M01.060.116'], ['G05.090.403.180', 'G05.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.550.475', 'N01.224.935.698.489', 'N06.850.505.400.975.550.475', 'N06.850.520.308.985.550.475'], ['M01.060.703.520'], ['Z01.252.245.723'], ['E05.318.740.600.800.725', 'N05.715.350.200.700... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Adult polycystic kidney disease: ultrasonographic and computed tomographic appearance. | Sixteen patients with adult polycystic kidney disease (PKD) were studied by gray scale B mode ultrasonography. The nephrosonographic appearance of adult PKD is a spectrum ranging from kidneys of normal size to enlarged kidneys with multiple variable-sized cysts. Strong focal cortical echoes were present in patients wit... | ['Adult', 'Aged', 'Cysts', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Kidney', 'Liver', 'Liver Diseases', 'Male', 'Middle Aged', 'Polycystic Kidney Diseases', 'Tomography, X-Ray Computed', 'Ultrasonography'] | 103,893 | [['M01.060.116'], ['M01.060.116.100'], ['C04.182', 'C23.300.306'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['A03.620'], ['C06.552'], ['M01.060.116.630'], ['C12.777.419.403.875', 'C13.351.968.419.403.875', 'C16.131.077.717', 'C16.320.184.625'], ['E01.370.350.350.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Using State Birth Defects Registries to Evaluate Regional Critical Congenital Heart Disease Newborn Screening. | BACKGROUND: Most states have now passed legislation mandating pulse oximetry for all newborns, or have promulgated regulations or guidelines to encourage use of routine pulse oximetry. State-based birth defects registries may be well positioned to track and evaluate critical congenital heart disease (CCHD) screening co... | ['Congenital Abnormalities', 'Female', 'Heart Defects, Congenital', 'Hospitals', 'Humans', 'Infant, Newborn', 'Male', 'Neonatal Screening', 'New England', 'Oximetry', 'Prenatal Diagnosis', 'Registries'] | 29,152,920 | [['C16.131'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.370.225.910', 'E01.370.500.580', 'E05.200.910', 'E05.318.308.980.438.580.580', 'N02.421.726.233.443.816', 'N05.715.360.300.800.438.500.575', 'N06.850.520.308.980.... | ['Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Diagnosis of legionellosis by microagglutination test--comparison to indirect immunofluorescent antibody method]. | We studied the micro-agglutination method (MAT) for the diagnosis of legionellosis. Serum samples were collected from 44 clinically legionellosis suspected patients (17 positive with indirect immunofluorescent antibody technique [IFA] and 27 IFA negatives) and 20 healthy adults (25-30 years old). MAT showed negative re... | ['Adult', 'Agglutination Tests', 'Fluorescent Antibody Technique, Indirect', 'Humans', 'Legionellosis', 'Sensitivity and Specificity'] | 9,011,118 | [['M01.060.116'], ['E01.370.225.812.735.050', 'E05.200.812.735.050', 'E05.478.594.760.050'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.551.512.240.310', 'E05.200.500.607.512.240.310', 'E05.200.750.551.512.240.310', 'E05.478.583.375.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.400.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficacy of endoscopic stapled transanal rectal resection for the treatment of rectocele. | OBJECTIVE: The objective of the study was to determine the efficacy of endoscopic stapled transanal rectal resection for the treatment of rectocele.PATIENTS AND METHODS: For this purpose, the data were collected from 61 patients with severe rectocele that underwent endoscopic stapled transanal rectal resection within t... | ['Adult', 'Aged', 'Constipation', 'Digestive System Surgical Procedures', 'Female', 'Humans', 'Male', 'Middle Aged', 'Natural Orifice Endoscopic Surgery', 'Patient Satisfaction', 'Rectocele', 'Rectum', 'Surgical Stapling', 'Treatment Outcome'] | 25,555,885 | [['M01.060.116'], ['M01.060.116.100'], ['C23.888.821.150'], ['E04.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.388.250.630', 'E04.502.250.630'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600'], ['C06.405.469.860.810', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Familial hemiplegic migraine and autosomal dominant arteriopathy with leukoencephalopathy (CADASIL). | Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a recently described familial cerebrovascular disorder shown to map to chromosome 19q12. Familial hemiplegic migraine has also been shown in some families to map close to the CADASIL locus. The fully developed CADASI... | ['Adult', 'Aged', 'Brain', 'Brain Diseases', 'Cerebral Arterial Diseases', 'Cerebral Infarction', 'Chromosome Mapping', 'Corpus Callosum', 'Female', 'Hemiplegia', 'Humans', 'Infarction', 'Lod Score', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Migraine Disorders', 'Pedigree', 'Phenotype', 'Spinal Cord', 'Synd... | 7,486,874 | [['M01.060.116'], ['M01.060.116.100'], ['A08.186.211'], ['C10.228.140'], ['C10.228.140.300.510.200', 'C14.907.253.560.200'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['E05.393.183'], ['A08.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Head lice. Dimeticone is the pediculicide of choice. | Infestation of the scalp by head lice, or pediculosis, is a common, unpleasant but harmless parasitosis. For patients with pediculosis, which topical treatment eradicates the parasites effectively while causing the least harm? We reviewed the available evidence using the standard Prescrire methodology. Lice can be erad... | ['Dimethylpolysiloxanes', 'Humans', 'Insecticides', 'Lice Infestations', 'Scalp Dermatoses'] | 25,162,097 | [['D02.756.650.700.150', 'D05.750.900.850.150', 'D25.720.900.850.150', 'J01.637.051.720.900.850.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.031.700.491', 'D27.888.723.491'], ['C01.610.858.211.465', 'C17.800.838.775.580'], ['C17.800.738']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Characterization and Correction of Geometric Distortions in 814 Diffusion Weighted Images. | INTRODUCTION: Diffusion Weighted Imaging (DWI), which is based on Echo Planar Imaging (EPI) protocols, is becoming increasingly important for neurosurgical applications. However, its use in this context is limited in part by significant spatial distortion inherent to EPI.METHOD: We evaluated an efficient algorithm for ... | ['Algorithms', 'Brain Neoplasms', 'Diffusion Magnetic Resonance Imaging', 'Echo-Planar Imaging', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Male', 'Radiography'] | 27,027,775 | [['G17.035', 'L01.224.050'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E01.370.350.825.500.150'], ['E01.370.350.825.500.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.700']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Non-malignant cells in pleural fluid]. | Insufficient attention has been paid to the cytological examination of cellular elements of the pleural fluid besides or in the absence of tumour cells. 108 cases studied due to pleural fluid were selected. They were characterized by the following: 1. each had histological diagnosis established by either pleuroscopy or... | ['Biopsy, Needle', 'Diagnosis, Differential', 'Endoscopy', 'Humans', 'Pleura', 'Pleural Effusion', 'Pleural Neoplasms', 'Pleurisy', 'Tuberculosis, Pleural'] | 7,845,663 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['E01.171'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.716', 'A10.615.789.736'], ['C... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biotransformation, a new approach to aminoglycoside biosynthesis: II. Gentamicin. | Utilizing a paromamine-producing mutant of Micromonospora purpurea blocked in the production of gentamicin, bioconversion of various minor gentamicin components into the gentamicin C complex was demonstrated. The compounds tested were structurally related to the gentamicin C's and are found as minor components in the g... | ['Biotransformation', 'Culture Media', 'Gentamicins', 'Micromonospora', 'Mutation', 'Oxalates'] | 931,800 | [['G03.171', 'G03.787.225', 'G07.690.725.225'], ['D27.720.470.305', 'E07.206'], ['D09.408.051.374'], ['B03.300.390.400.500.500', 'B03.510.024.925.500', 'B03.510.415.400.500.500', 'B03.510.460.410.500.500'], ['G05.365.590'], ['D02.241.081.337.593']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Escherichia coli rho factor induces release of yeast RNA polymerase II but not polymerase I or III. | Purified RNA polymerase II (pol II) from the yeast Saccharomyces cerevisiae pauses without releasing at many locations during in vitro transcription. Pausing can be induced by intrinsic DNA sequence as well as by specific DNA bound proteins such as the RNA pol I termination factor, Reb1p, or lac repressor. Addition of ... | ['Adenosine Triphosphate', 'Cell-Free System', 'Escherichia coli', 'Kinetics', 'RNA Polymerase I', 'RNA Polymerase II', 'RNA Polymerase III', 'RNA, Messenger', 'Regulatory Sequences, Nucleic Acid', 'Rho Factor', 'Saccharomyces cerevisiae', 'Templates, Genetic', 'Terminator Regions, Genetic', 'Transcription, Genetic'] | 9,560,200 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['A11.284.835.168'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.374.661', 'G02.111.490'], ['D08.811.913.696.445.735.270.750'], ['D08.811.913.696.445.735.270.762'], ['D08.811.913.696.445.735.270.775'], ['D13.444.735.544'],... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Suitability of replacement markers for functional analysis studies in Saccharomyces cerevisiae. | The complete yeast sequence contains a large proportion of genes whose biological function is completely unknown. One approach to elucidating the function of these novel genes is by quantitative methods that exploit the concepts of metabolic control analysis. An important first step in such an analysis is to determine ... | ['Anti-Bacterial Agents', 'Base Sequence', 'Drug Resistance, Microbial', 'Genes, Fungal', 'Genetic Markers', 'Gentamicins', 'Histidine', 'Molecular Sequence Data', 'Saccharomyces cerevisiae'] | 9,509,575 | [['D27.505.954.122.085'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G06.225', 'G07.690.773.984.269'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['D23.101.387', 'G05.695.450'], ['D09.408.051.374'], ['D12.125.072.329', 'D12.125.142.308'], ['L01.453.245.667']... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Abnormalities of the glucose transporter at the blood-brain barrier and in brain in Alzheimer's disease. | We have previously demonstrated the glucose transporter (GT) by [3H]cytochalasin B binding and immunocytochemistry in brain and in cerebral microvessels which form the blood-brain barrier. In this study, we assessed the GT protein in the frontal cortex, hippocampus, cerebellum, and cerebral microvessels in subjects wit... | ['Aged', 'Alzheimer Disease', 'Blood-Brain Barrier', 'Brain', 'Humans', 'Microcirculation', 'Monosaccharide Transport Proteins'] | 2,602,426 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['A07.035', 'A08.186.211.035'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.330.100.645'], ['D12.776.157.530.500', 'D12.776.543.585.500']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Chronic knockdown of the nucleus of the solitary tract AT1 receptors increases blood inflammatory-endothelial progenitor cell ratio and exacerbates hypertension in the spontaneously hypertensive rat. | AT1 receptor subtype a (AT1Ra) expression is increased in the nucleus of the solitary tract (NTS) in spontaneously hypertensive rat (SHR) compared with Wistar Kyoto controls. However, the chronic role of AT1Ra in the NTS for cardiovascular control is not well understood. In this study, we investigated the hypothesis th... | ['Animals', 'Blood Pressure', 'Cells, Cultured', 'Disease Progression', 'Endothelial Cells', 'Gene Expression Regulation', 'Gene Knockdown Techniques', 'Hypertension', 'Inflammation', 'RNA, Messenger', 'Rats', 'Rats, Inbred SHR', 'Rats, Inbred WKY', 'Real-Time Polymerase Chain Reaction', 'Receptor, Angiotensin, Type 1'... | 23,547,238 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A11.251'], ['C23.550.291.656'], ['A11.436.275'], ['G05.308'], ['E05.393.335.500'], ['C14.907.489'], ['C23.550.470'], ['D13.444.735.544'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.300', 'B01.050.150.900.649.313.992.635.505.700.400.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exploring the biological potential of urea derivatives against mPGES-1: a combination of quantum mechanics, pharmacophore modelling and QSAR analyses. | In the present molecular modelling study, recently discovered 36 selective urea derivatives were considered to develop pharmacophore based 3D-QSAR model coupled with quantum mechanics (QM) calculations to uncover the essential structural features of urea molecules for mPGES-1 inhibition. The 3D-QSAR model was selected ... | ['Enzyme Activation', 'Enzyme Inhibitors', 'Hydrophobic and Hydrophilic Interactions', 'Inhibitory Concentration 50', 'Intramolecular Oxidoreductases', 'Models, Molecular', 'Molecular Structure', 'Prostaglandin-E Synthases', 'Quantitative Structure-Activity Relationship', 'Quantum Theory', 'Urea'] | 22,946,531 | [['G02.111.263', 'G03.328'], ['D27.505.519.389'], ['G02.409'], ['E05.940.350', 'G07.690.936.563'], ['D08.811.399.475'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['D08.811.399.475.600'], ['G02.111.830.500', 'G07.690.773.997.500'], ['H01.671.579.800'], ['D02.065.950']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Anti-tumoral activity of L and D isomers of aspartic acid beta-hydroxamate on L5178Y leukemia. | D and L isomers of aspartic acid beta-hydroxamate (respectively DAH and LAH) were compared for their in vitro and in vivo activity against the murine leukemia L5178Y and their tolerance in vivo in DBA/2 mice. DAH and LAH displayed comparable cytotoxic activity against L5178Y leukemia in vitro. Death of leukemia cells w... | ['Animals', 'Asparagine', 'Aspartic Acid', 'Drug Screening Assays, Antitumor', 'Isomerism', 'Leukemia L5178', 'Mice', 'Mice, Inbred DBA'] | 1,917,141 | [['B01.050'], ['D12.125.068.060', 'D12.125.095.165', 'D12.125.154.049'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['G02.111.570.685', 'G02.607.445'], ['C04.557.337.372.602', 'C04.619.531.602'], ['B01.050.150.900.649.313.992.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical study of the improvement gastrostomy in pancreaticoduodenectomy]. | OBJECTIVE: To explore the clinical significance of improvement gastrostomy in pancreaticoduodenectomy.METHODS: Clinical data of 82 patients who underwent pancreaticoduodenectomy and jejunostomy from November 2004 to December 2006 were collected, among which 36 patients received improvement gastrostomy (treatment group)... | ['Adult', 'Aged', 'Female', 'Gastroparesis', 'Gastrostomy', 'Humans', 'Male', 'Middle Aged', 'Pancreaticoduodenectomy', 'Postoperative Complications', 'Treatment Outcome'] | 18,241,564 | [['M01.060.116'], ['M01.060.116.100'], ['C06.405.748.543', 'C23.888.592.636.263'], ['E04.210.496', 'E04.579.408'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.210.760'], ['C23.550.767'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cerebral hemodynamics as a predictor of stroke in adult patients with moyamoya disease: a prospective observational study. | Moyamoya disease is an obliterative vasculopathy of the large arteries at the base of the brain. In the US, it most commonly affects women in their 3rd and 4th decades of life, frequently causing ischemic stroke. The natural history of this disorder is not well described. It is very likely that hemodynamic factors play... | ['Adult', 'Brain', 'Cerebral Arteries', 'Cerebrovascular Circulation', 'Comorbidity', 'Female', 'Hemodynamics', 'Humans', 'Longitudinal Studies', 'Moyamoya Disease', 'Neurosurgical Procedures', 'Outcome Assessment, Health Care', 'Patient Selection', 'Positron-Emission Tomography', 'Predictive Value of Tests', 'Prospect... | 19,335,132 | [['M01.060.116'], ['A08.186.211'], ['A07.015.114.228'], ['G09.330.100.159'], ['N05.715.350.225', 'N06.850.490.687'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['C10.228.140.300.200.600', 'C10.228.140.300.5... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Are service and patient indicators different in the presence or absence of nurse practitioners? The EDPRAC cohort study of Australian emergency departments. | OBJECTIVES: To evaluate the impact of nurse practitioner (NP) service in Australian public hospital emergency departments (EDs) on service and patient safety and quality indicators.DESIGN AND SETTING: Cohort study comprising ED presentations (July 2013-June 2014) for a random sample of hospitals, stratified by state/te... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Australia', 'Child', 'Child, Preschool', 'Emergency Nursing', 'Emergency Service, Hospital', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Length of Stay', 'Logistic Models', 'Male', 'Middle Aged', 'Models, Nursing', 'Nurse Practitioners', "Nurse's Role", 'Outco... | 31,366,634 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.639.100', 'Z01.678.100.373'], ['M01.060.406'], ['M01.060.406.448'], ['H02.478.676.200', 'N02.421.533.200'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Protein Methionine Sulfoxide Dynamics in Arabidopsis thaliana under Oxidative Stress. | Reactive oxygen species such as hydrogen peroxide can modify proteins via direct oxidation of their sulfur-containing amino acids, cysteine and methionine. Methionine oxidation, studied here, is a reversible posttranslational modification that is emerging as a mechanism by which proteins perceive oxidative stress and f... | ['Arabidopsis', 'Arabidopsis Proteins', 'Gene Deletion', 'Glutathione Transferase', 'Hydrogen Peroxide', 'Isoenzymes', 'Kinetics', 'Methionine', 'Molecular Sequence Annotation', 'Oxidation-Reduction', 'Oxidative Stress', 'Plant Leaves', 'Plants, Genetically Modified', 'Protein Processing, Post-Translational'] | 25,693,801 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G05.365.590.762.320', 'G05.558.800.320'], ['D08.811.913.225.500'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D08.811.348', 'D12.776.800.300'], ['G01.374.661', 'G02.111.490'], ['D02.886.030.676', 'D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Experimental study on slow-speed elongation injury of the peripheral nerve: electrophysiological and histological changes. | Slow-speed elongation of the sciatic nerves was induced in 41 rabbits by lengthening the osteotomized femur by 2.1 mm/day with an external fixator. Time courses were monitored. About 2 weeks after elongation began, the amplitude of the compound nerve action potentials decreased, and delayed latency began. Histological ... | ['Action Potentials', 'Animals', 'Bone Lengthening', 'Electrophysiology', 'Female', 'Neural Conduction', 'Rabbits', 'Sciatic Nerve'] | 11,484,121 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['E04.555.120'], ['H01.158.344.528', 'H01.158.782.236'], ['G07.265.753', 'G11.561.601'], ['B01.050.150.900.649.313.968.700'], ['A08.800.800.720.450.760']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
An unusual strain of hepatitis C virus in New Zealand. | AIMS: To investigate the prevalence of hepatitis C virus (HCV) viraemia in selected cohorts of New Zealand patients and to examine the strains of hepatitis C virus circulating in New Zealand.METHODS: Hepatitis C viraemia was identified using a highly sensitive polymerase chain reaction (PCR) assay to detect HCV ribonuc... | ['Blood Transfusion', 'Cohort Studies', 'Gene Expression', 'Hemophilia A', 'Hepacivirus', 'Hepatitis Antibodies', 'Hepatitis C', 'Hepatitis C Antibodies', 'Humans', 'New Zealand', 'Polymerase Chain Reaction', 'Polymorphism, Restriction Fragment Length', 'Prevalence', 'Prisoners', 'RNA, Viral', 'Risk Factors', 'Substanc... | 7,688,109 | [['E02.095.135'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G05.297'], ['C15.378.100.100.500', 'C15.378.100.141.500', 'C15.378.463.500', 'C16.320.099.500'], ['B04.450.380', 'B04.820.578.344.475'], ['D12.776.124.486.485.114.254.450', 'D12.776.124.790.651.114.254.450', 'D12.776.377.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Development and evaluation of an enzyme-linked immunosorbent assay for endotoxin in milk. | A double antibody sandwich enzyme-linked immunosorbent assay (ELISA) was developed for the detection of endotoxin in milk samples. Bovine and rabbit antisera raised in response to vaccination with the J5 mutant of Escherichia coli 0111:B4 were used. Antiserum to this mutant has been shown to be cross-reactive with endo... | ['Animals', 'Cattle', 'Endotoxins', 'Enzyme-Linked Immunosorbent Assay', 'False Positive Reactions', 'Limulus Test', 'Lipopolysaccharides', 'Mastitis, Bovine', 'Milk'] | 3,188,375 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D23.946.123.329'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E01.354.506'], ['E01.370.225.124.470', 'E01.370.225.875.150.570', 'E05.091.570', 'E05.200.124.470', 'E05.200.875.150.570'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
PARP-inhibitors in BRCA-associated pancreatic cancer. | Recent data suggests that treating patients with pancreatic cancer that express mutations in BRCA1, BRCA2, and PALB2 with chemotherapy which targets the DNA repair defect in these cells, such as platinum based therapies or PARPi [poly (ADP-ribose) polymerase inhibitor], may be more beneficial in these patients. Moreove... | ['Antineoplastic Combined Chemotherapy Protocols', 'BRCA1 Protein', 'BRCA2 Protein', 'Cisplatin', 'Clinical Trials as Topic', 'Deoxycytidine', 'Enzyme Inhibitors', 'Humans', 'Mutation', 'Pancreatic Neoplasms', 'Phthalazines', 'Piperazines', 'Poly(ADP-ribose) Polymerase Inhibitors', 'Poly(ADP-ribose) Polymerases', 'Surv... | 25,076,338 | [['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D12.776.313.125', 'D12.776.624.776.100', 'D12.776.660.100', 'D12.776.744.100', 'D12.776.930.137'], ['D12.776.313.249', 'D12.776.624.776.101', 'D12.776.660.105'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E05.318.372.250.250', 'N05.715.360.330.250.250'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Executive dysfunction in hyperhomocystinemia responds to homocysteine-lowering treatment. | An elevated serum homocysteine level is a risk factor for the development of cognitive impairment. Reported is a late-onset case of hyperhomocystinemia due to a vitamin B12 metabolic deficit (cobalamin C) with cognitive impairment, primarily in frontal/executive function. After homocysteine-lowering therapy, the patien... | ['Adult', 'Anticoagulants', 'Betaine', 'Cognition Disorders', 'Confusion', 'Disease Progression', 'Drug Therapy, Combination', 'Folic Acid', 'Frontal Lobe', 'Homocysteine', 'Humans', 'Hyperhomocysteinemia', 'Leukoaraiosis', 'Magnetic Resonance Imaging', 'Male', 'Methylmalonic Acid', 'Remission Induction', 'Seizures', '... | 15,851,736 | [['M01.060.116'], ['D27.505.954.502.119'], ['D02.092.877.883.077', 'D02.675.276.125'], ['F03.615.250'], ['C10.597.606.337', 'C23.888.592.604.339', 'F01.700.250'], ['C23.550.291.656'], ['E02.319.310'], ['D03.633.100.733.631.400'], ['A08.186.211.200.885.287.500.270'], ['D02.886.030.498', 'D12.125.166.498'], ['B01.050.150... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Therapeutic action of meliacine, a plant-derived antiviral, on HSV-induced ocular disease in mice. | Ocular herpes simplex virus type-1 (HSV-1) infections remain an important cause of corneal disease which may result in a loss of vision. Meliacine (MA), an antiviral activity present in crude leaf extracts of Melia azedarach L. that inhibits HSV-1 multiplication in vitro, was studied in a murine herpetic stromal kerati... | ['Animals', 'Antiviral Agents', 'Eye', 'Herpesvirus 1, Human', 'Keratitis, Herpetic', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Peptides', 'Phytotherapy', 'Plant Extracts', 'Plant Proteins', 'Virus Replication'] | 12,384,095 | [['B01.050'], ['D27.505.954.122.388'], ['A01.456.505.420', 'A09.371'], ['B04.280.382.100.750.390'], ['C01.375.725.465', 'C01.925.256.466.382.465', 'C01.925.325.465', 'C11.204.564.425', 'C11.294.800.475'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Novel combined insulin-like 3 variations of a single nucleotide in cryptorchidism. | Background Insulin-like 3 hormone (INSL3) is involved in the process of testicular descent, and has been thoroughly studied in cryptorchidism. However, INSL3 allelic variations found in the human genome were heterozygous and only a few of them were found exclusively in patients with cryptorchidism. Under this perspecti... | ['Alleles', 'Amino Acid Substitution', 'Biomarkers', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Cryptorchidism', 'Follow-Up Studies', 'Homozygote', 'Humans', 'Infant', 'Insulin', 'Male', 'Polymorphism, Single Nucleotide', 'Prognosis', 'Proteins'] | 31,444,964 | [['G05.360.340.024.340.030'], ['E05.393.420.601.035', 'G05.558.109'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['C12.294.829.258', 'C12.706.258', 'C16.131.939.258', 'C19.391.829.258'], ['E05.318.372.500.750.249', 'N05.715.360.330.5... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Study of the effects of calcium antagonists on respiration mechanics in patients with occlusive ventilation impairment]. | In 113 patients and 33 controls the bronchodilating effect of three most frequently used calcium channel blockers nifedipine, verapamil and diltiazem was studied. The group comprised 76 men and 41 women aged 20 to 60 years, with bronchospastic conditions of various aetiology. The Jaeger Bodytest apparatus was used. The... | ['Adult', 'Bronchial Spasm', 'Calcium Channel Blockers', 'Diltiazem', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nifedipine', 'Verapamil'] | 2,815,744 | [['M01.060.116'], ['C08.127.321'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D03.633.100.079.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D03.383.725.203.540'], ['D02.092.471.683.953']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ventilation mode and outcome of premature infants with congenital chylothorax. | BACKGROUND: Congenital chylothorax (CC) is a rare and potentially life-threatening condition. Over 50% occurs at birth and is considered as the most common cause of neonatal thoracic fluid collection.OBJECTIVES: To analyse the main clinical and respiratory features of a contemporary group of CC infants.METHODS: Databas... | ['Chylothorax', 'Cohort Studies', 'Female', 'Gestational Age', 'High-Frequency Ventilation', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Infant, Premature, Diseases', 'Intermittent Positive-Pressure Ventilation', 'Male', 'Prognosis', 'Respiration, Artificial', 'Respiratory Distress Syndrome, Newborn', 'Retrospec... | 22,185,327 | [['C08.528.142'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G07.345.500.325.235.968', 'G08.686.320'], ['E02.041.625.508', 'E02.880.820.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['C16.614.521'], ['E02.041.625.790.550', 'E0... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The stereochemistry of the major rat hepatic microsomal metabolites of 7,9-dimethylbenz[c]acridine and 7,10-dimethylbenz[c]acridine. | The monofunctionalized dihydrodiol metabolites of 7,9-dimethylbenz[c]acridine and 7,10-dimethylbenz[c]acridine formed in incubations with rat liver microsomes from untreated and phenobarbital and 3-methylcholanthrene-pretreated rats were isolated by reversed-phase high performance liquid chromatography. The relative am... | ['Acridines', 'Animals', 'Carcinogens', 'Circular Dichroism', 'Magnetic Resonance Spectroscopy', 'Male', 'Microsomes, Liver', 'Molecular Conformation', 'Rats', 'Rats, Sprague-Dawley', 'Spectrophotometry, Ultraviolet'] | 7,766,802 | [['D03.633.300.046'], ['B01.050'], ['D27.888.569.100'], ['E05.196.867.151'], ['E05.196.867.519'], ['A11.284.835.540.541'], ['G02.111.570.820'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
How much does heterosexual commercial sex contribute to India's HIV epidemic? | Through a search, we identified five models of India's HIV epidemic, all of which articulate the hypothesis that heterosexual commercial sex drives India's HIV epidemic. All five models assume more female sex workers (FSWs) than have been mapped (counted), and more than can be inferred from men's sexual behaviour. With... | ['Acquired Immunodeficiency Syndrome', 'Adolescent', 'Adult', 'Condoms', 'Disease Outbreaks', 'Female', 'HIV', 'Heterosexuality', 'Humans', 'India', 'Male', 'Middle Aged', 'Sex Work'] | 17,062,176 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.057'], ['M01.060.116'], ['E07.190.270.150'], ['N06.850.290'], ['B04.820.650.589.650.350'], ['F01.145.802.975.400', 'G08.686.867.400'], ['B01.0... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Mechanism for the T4 lymphopenia of AIDS. | I suggest that the T4 lymphopenia of AIDS may be caused by antibodies raised against the human immunodeficiency virus that block the generation of T4 cells. | ['Acquired Immunodeficiency Syndrome', 'Antibodies, Viral', 'Autoimmune Diseases', 'CD4 Antigens', 'CD4-Positive T-Lymphocytes', 'Female', 'HIV Envelope Protein gp120', 'HIV-1', 'Humans', 'Lymphopenia', 'Models, Theoretical'] | 7,902,577 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['C20.111'], ['D12.776.543.750.705.852.420.810.500', 'D12... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Autonomic and neuroendocrine responses to a psychosocial stressor in adults with autistic spectrum disorder. | Objective of the study was to replicate in adults our previous findings of decreased heart rate and normal endocrine responses to stress in autistic children and to elucidate the discrepancy between autonomic and endocrine stress responses by including epinephrine, norepinephrine, oxytocin and vasopressin measurements.... | ['Adrenocorticotropic Hormone', 'Adult', 'Autistic Disorder', 'Autonomic Nervous System', 'Epinephrine', 'Female', 'Humans', 'Male', 'Norepinephrine', 'Oxytocin', 'Psychology', 'Speech', 'Stress, Psychological', 'Vasopressins'] | 16,865,550 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['M01.060.116'], ['F03.625.164.113.500'], ['A08.800.050'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
[Effect of chemical carcinogens on the synaptic transmission of excitation in the sympathetic ganglia of rats]. | Acute experiments on rats were performed to study the influence of water-soluble chemical carcinogens on synaptic transmission via the inferior mesenteric sympathetic ganglion. Synaptic transmission was studied before and after intravenous injection of the enterotropic carcinogen 1,2-dimethylhydrazine (DMH) and N-nitro... | ['Action Potentials', 'Animals', 'Dimethylhydrazines', 'Ephedrine', 'Epinephrine', 'Ganglia, Sympathetic', 'Hexamethonium', 'Hexamethonium Compounds', 'Methylhydrazines', 'Methylnitrosourea', 'Nitrosourea Compounds', 'Rats', 'Solubility', 'Synapses', 'Synaptic Transmission', 'Trimethaphan'] | 2,861,867 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['D02.442.600.400'], ['D02.033.100.624.302', 'D02.033.755.624.302', 'D02.092.063.624.302', 'D02.092.471.683.430'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['A08.3... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of nutraceuticals on sexual satisfaction and lower urinary tract symptoms in a cohort of young-old men. | The aim of this study was to evaluate the effects of nutraceuticals containing multiple supplemental facts (Virherbe®/Rekupros®) on sexual satisfaction and lower urinary tract symptoms (LUTS) in young-old men. In an open-label trial, 40 males (mean age 66 ± 13) with sexual disturbances and mild LUTS but without cogniti... | ['Aged', 'Cohort Studies', 'Dietary Supplements', 'Humans', 'Libido', 'Lower Urinary Tract Symptoms', 'Male', 'Orgasm', 'Prospective Studies', 'Quality of Life', 'Sexual Behavior', 'Treatment Outcome'] | 29,168,235 | [['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G07.203.300.456', 'J02.500.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.739.794.511'], ['C23.888.942.343'], ['G08.686.784.460'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'H... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Evaluation of seven tumor markers (CA 50, CA 19-9, CA 19-9 TruQuant, CA 72-4, CA 195, carcinoembryonic antigen, and tissue polypeptide antigen) in the pretreatment sera of patients with gastric carcinoma. | Preoperative serum levels of the tumor markers CA 50, CA 19-9, CA 19-9 TruQuant, CA 72-4, CA 195, carcinoembryonic antigen (CEA), and tissue polypeptide antigen (TPA) were measured in 94 patients with well-staged adenocarcinoma of the stomach and in 15 patients with benign gastric diseases. In all patients with carcino... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antigens, Neoplasm', 'Antigens, Tumor-Associated, Carbohydrate', 'Biomarkers, Tumor', 'Carcinoembryonic Antigen', 'Humans', 'Middle Aged', 'Peptides', 'Stomach Neoplasms', 'Tissue Polypeptide Antigen'] | 1,544,112 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.050.285'], ['D23.050.285.050', 'D23.050.550.325', 'D23.101.140.075'], ['D23.101.140'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Esophageal injuries]. | Despite progress in the management of esophageal perforations by early diagnosis, antibiotics, monitoring, and respiratory and nutritional support, it still remains as a disasterous condition. The most common cause of esophageal perforation is iatrogenic disruption. The result in the management of esophageal perforatio... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Esophageal Perforation', 'Esophagus', 'Female', 'Foreign Bodies', 'Humans', 'Iatrogenic Disease', 'Male', 'Middle Aged', 'Retrospective Studies', 'Rupture', 'Time Factors', 'Treatment Outcome', 'Wounds, Gunshot', 'Wounds, Stab'] | 11,705,168 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['C06.405.117.468', 'C26.348'], ['A03.556.875.500'], ['C26.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.291.875'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Duodenal ulcer in systemic mastocytosis]. | Two cases of systemic mastocytosis are presented. Both patients had peptic ulceration. Greatly raised values on investigation of gastric acid secretion in patients with therapy-resistant peptic ulceration and normal serum gastrin should raise the suspicion of systemic mastocytosis. | ['Adult', 'Diagnosis, Differential', 'Duodenal Ulcer', 'Female', 'Gastric Acid', 'Humans', 'Male', 'Mastocytosis', 'Middle Aged'] | 1,858,180 | [['M01.060.116'], ['E01.171'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['A12.200.307.603'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.565.465', 'C17.800.508', 'C20.543.520.350'], ['M01.060.116.630']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Taurine release in the rat vas deferens is modulated by Ca2+ and is independent of contractions. | Electrical field stimulation induces taurine release in rat vas deferens. In the present study, it was investigated if this release is secondary to contraction. The influence of Ca2+ and of the stimulation conditions was also studied. Contractions evoked by electrical field stimulation (5 Hz/270 pulses, transverse or l... | ['Animals', 'Caffeine', 'Calcium', 'Calcium Channel Blockers', 'Coagulants', 'Dantrolene', 'Electric Stimulation', 'Male', 'Rats', 'Rats, Wistar', 'Ryanodine', 'Taurine', 'Vas Deferens'] | 10,448,887 | [['B01.050'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D27.505.954.502.270'], ['D03.383.129.308.432.555.287'], ['E05.723.402'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Optimisation of microencapsulation of turmeric extract for masking flavour. | The aim of this study was to evaluate the odour masking property, encapsulation efficiency and physicochemical properties of turmeric extract prepared by a binary blend of wall materials, i.e. brown rice flour (BRF) and beta-cyclodextrin (â-CD). Response surface methodology was applied to investigate the effect of enca... | ['Curcuma', 'Drug Compounding', 'Gas Chromatography-Mass Spectrometry', 'Odorants', 'Plant Extracts'] | 26,471,609 | [['B01.650.940.800.575.912.250.618.937.900.166'], ['E05.916.270'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G16.500.275.640', 'N06.230.480'], ['D20.215.784.500', 'D26.667']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Nitrogen dioxide formation during inhaled nitric oxide therapy. | BACKGROUND: Nitrogen dioxide (NO2) is a toxic by-product of inhalation therapy with nitric oxide (NO). The rate of NO2 formation during NO therapy is controversial.METHODS: The formation of NO2 was studied under dynamic flows emulating a base case NO ventilator mixture containing 80 ppm NO in a 90% oxygen matrix. The d... | ['Administration, Inhalation', 'Bronchodilator Agents', 'Humans', 'Infant, Newborn', 'Kinetics', 'Nitric Oxide', 'Nitrogen Dioxide', 'Spectrophotometry', 'Vasodilator Agents'] | 10,053,039 | [['E02.319.267.050'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G01.374.661', 'G02.111.490'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D01.362.635.600', 'D01.625.550.525', 'D01.650.550.587.625'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Non-covalent polyvalent ligands by self-assembly of small glycodendrimers: a novel concept for the inhibition of polyvalent carbohydrate-protein interactions in vitro and in vivo. | Polyvalent carbohydrate-protein interactions occur frequently in biology, particularly in recognition events on cellular membranes. Collectively, they can be much stronger than corresponding monovalent interactions, rendering it difficult to control them with individual small molecules. Artificial macromolecules have b... | ['Animals', 'Carbohydrate Conformation', 'Carbohydrate Sequence', 'Computational Biology', 'Enzyme-Linked Immunosorbent Assay', 'Erythrocytes', 'Glycoconjugates', 'Hemolysis', 'Humans', 'Immunoglobulin M', 'In Vitro Techniques', 'Ligands', 'Macaca fascicularis', 'Magnetic Resonance Spectroscopy', 'Microscopy, Atomic Fo... | 16,231,293 | [['B01.050'], ['G02.111.570.820.235'], ['G02.111.570.160', 'L01.453.245.667.160'], ['H01.158.273.180', 'L01.313.124'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D09.400'], ['C23.550.403', 'G12... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Eosinopenia and post-hospital outcomes in critically ill non-cardiac vascular surgery patients. | BACKGROUND AND AIMS: Eosinopenia is a marker for acute inflammation. We hypothesized that eosinopenia at Intensive Care Unit (ICU) admission in vascular surgery patients who receive critical care, would be associated with increased mortality following hospital discharge.METHODS AND RESULTS: We performed a two-center ob... | ['Aged', 'Aged, 80 and over', 'Boston', 'Critical Illness', 'Eosinophils', 'Female', 'Humans', 'Leukocyte Count', 'Male', 'Middle Aged', 'Patient Discharge', 'Predictive Value of Tests', 'Risk Assessment', 'Risk Factors', 'Time Factors', 'Treatment Outcome', 'Vascular Diseases', 'Vascular Surgical Procedures'] | 31,248,714 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.567.875.550.510.210', 'Z01.433.210'], ['C23.550.291.625'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Availability of polycyclic aromatic hydrocarbons to earthworms (Eisenia andrei, Oligochaeta) in field-polluted soils and soil-sediment mixtures. | The bioavailability of polycyclic aromatic hydrocarbons (PAHs) for earthworms (Eisenia andrei) was experimentally determined in seven field-polluted soils and 15 soil-sediment mixtures. The pore-water concentration of most PAHs was higher than predicted. However, most of the compound was associated with dissolved organ... | ['Animals', 'Biological Availability', 'Geologic Sediments', 'Kinetics', 'Oligochaeta', 'Polycyclic Aromatic Hydrocarbons', 'Soil', 'Soil Pollutants'] | 12,685,711 | [['B01.050'], ['G03.787.151', 'G07.690.725.129'], ['G01.311.330', 'G16.500.320'], ['G01.374.661', 'G02.111.490'], ['B01.050.500.091.657'], ['D02.455.426.559.847', 'D04.615'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D27.888.284.756']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Rapidly involuting congenital haemangioma of the liver. | Rapidly involuting congenital haemangiomas (RICHs) are rare benign vascular tumours of infancy. They are generally asymptomatic, but can present with thrombocytopaenia and coagulopathy. Significant complications including life-threatening bleeding, high-output heart failure and liver failure, though rare, can occur. RI... | ['Blood Transfusion', 'Conservative Treatment', 'Hemangioma', 'Humans', 'Infant, Newborn', 'Liver Neoplasms', 'Magnetic Resonance Imaging', 'Male', 'Thrombocytopenia', 'Ultrasonography, Doppler, Color'] | 29,871,961 | [['E02.095.135'], ['E02.197'], ['C04.557.645.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['E01.370.350.825.500'], ['C15.378.140.855'], ['E01.370.350.850.850.850.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of Lure Combinations Containing Essential Oils and Volatile Spiroketals for Detection of Host-Seeking Xyleborus glabratus (Coleoptera: Curculionidae: Scolytinae). | The invasive redbay ambrosia beetle, Xyleborus glabratus Eichhoff (Coleoptera: Curculionidae: Scolytinae), vectors the fungal pathogen (Raffaelea lauricola) that causes laurel wilt, a disease responsible for widespread mortality of trees in the Lauraceae in the southeastern United States. Early detection of incipient v... | ['Animals', 'Chemotaxis', 'Female', 'Furans', 'Insect Control', 'Oils, Volatile', 'Pheromones', 'Spiro Compounds', 'Weevils'] | 28,575,468 | [['B01.050'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['D03.383.312'], ['N06.850.780.200.650.425'], ['D10.627.675'], ['D23.641'], ['D02.455.426.779', 'D04.711'], ['B01.050.500.131.617.720.500.500.375.900']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Gadolinium-enhanced MRI in the evaluation of minimally invasive treatments of the prostate: correlation with histopathologic findings. | OBJECTIVES: To explore the use of magnetic resonance imaging (MRI) with gadolinium enhancement as a noninvasive method to image the extent of ablation after minimally invasive treatment. Minimally invasive methods for ablating prostatic tissue have emerged as a viable option in the treatment of prostate disease. As the... | ['Adenocarcinoma', 'Contrast Media', 'Cryotherapy', 'Gadolinium', 'Humans', 'Hyperthermia, Induced', 'Magnetic Resonance Imaging', 'Male', 'Minimally Invasive Surgical Procedures', 'Necrosis', 'Prostatectomy', 'Prostatic Neoplasms'] | 14,624,916 | [['C04.557.470.200.025'], ['D27.505.259.500', 'D27.720.259'], ['E02.258'], ['D01.268.558.362.484', 'D01.552.550.399.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.565'], ['E01.370.350.825.500'], ['E04.502'], ['C23.550.717'], ['E04.950.774.860.625'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Switching of G-protein usage by the calcium-sensing receptor reverses its effect on parathyroid hormone-related protein secretion in normal versus malignant breast cells. | The calcium-sensing receptor (CaR) is a G-protein-coupled receptor that signals in response to extracellular calcium and regulates parathyroid hormone secretion. The CaR is also expressed on normal mammary epithelial cells (MMECs), where it has been shown to inhibit secretion of parathyroid hormone-related protein (PTH... | ['Animals', 'Bone Neoplasms', 'Breast Neoplasms', 'Cell Line, Tumor', 'Cyclic AMP', 'Cyclic AMP-Dependent Protein Kinases', 'Female', 'GTP-Binding Protein alpha Subunits', 'Humans', 'Hypercalcemia', 'Lactation', 'MAP Kinase Signaling System', 'Mammary Glands, Animal', 'Mammary Neoplasms, Animal', 'Mice', 'Neoplasm Meta... | 18,621,740 | [['B01.050'], ['C04.588.149', 'C05.116.231'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['D08.811.277... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Urban public attitudes to the treatment of psychological problems and depression in general practice. | A previous national study of public attitudes to depression indicated that only 17% spontaneously mentioned their general practitioner as someone who could help with depression, in contrast to 79% of respondents being willing to consult their G.P. in a similar U.K. survey. The present study undertook to examine the pub... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Attitude of Health Personnel', 'Attitude to Health', 'Chi-Square Distribution', 'Depressive Disorder', 'Family Practice', 'Humans', 'Ireland', 'Male', 'Middle Aged', "Practice Patterns, Physicians'", 'Psychotic Disorders', 'Public Opinion', 'Registries', 'Sampling Studies... | 11,142,953 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['F01.100.150', 'N05.300.150'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['F03.600.300'], ['H02.403.340.500'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Effect of augmented sensorimotor input on learning verbal and nonverbal tasks among children with autism spectrum disorders. | Thirty-four children, with autism spectrum disorders, ages 4-14 years, were matched and randomly assigned to one of two conditions for learning a novel juice-making task and producing two novel words about the event. Seventeen sighted children were manually guided to perform the task and tactually prompted during imita... | ['Acoustic Stimulation', 'Adolescent', 'Child', 'Child Development Disorders, Pervasive', 'Child, Preschool', 'Feedback, Psychological', 'Female', 'Humans', 'Male', 'Mental Recall', 'Motor Activity', 'Recognition, Psychology', 'Verbal Learning'] | 24,234,676 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.057'], ['M01.060.406'], ['F03.625.164'], ['M01.060.406.448'], ['F01.058.288', 'F04.754.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['F01.145.632', 'G11.427.410.698'], ['F02.463.425.540.706'], ['F02.463.425.952']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Influence of dietary energy intake on prepubertal development of Brahman bulls. | Twelve Brahman bulls (paired by sire, weight and age) were assigned randomly and limit fed to gain either .10 to .25 (moderate gain; MG) or .75 to 1.0 (high gain: HG) kg.hd-1.d-1 to examine the effect of dietary energy on onset of puberty. Hip height (HH), scrotal circumference (SC) and serum samples (20 min for 6 h) w... | ['Animals', 'Blood Urea Nitrogen', 'Cattle', 'Eating', 'Energy Intake', 'Energy Metabolism', 'Growth Hormone', 'Hypothalamo-Hypophyseal System', 'Luteinizing Hormone', 'Male', 'Organ Size', 'Pituitary Hormone-Releasing Hormones', 'Random Allocation', 'Sexual Maturation', 'Testis', 'Testosterone', 'Triglycerides', 'Weig... | 2,185,207 | [['B01.050'], ['E01.370.225.124.100.115', 'E01.370.390.400.100', 'E05.200.124.100.115'], ['B01.050.150.900.649.313.500.380.271'], ['G07.203.650.283', 'G10.261.330'], ['G07.203.650.240.340'], ['G03.295'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['A06.688.357', 'A08.186.211.180.497.352.435', 'A08.186.211.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A dermatoglyphic survey of Kenyan schoolchildren. | The article reports on progress in the analysis of data from a dermatoglyphic survey of 6235 Kenyan schoolchildren, drawn from some 60 ethnic populations. The findings indicate considerable variation within Kenya for a majority of dermatoglyphic traits examined, often approaching the full sub-Saharan African range. The... | ['Child', 'Dermatoglyphics', 'Ethnic Groups', 'Female', 'Humans', 'Kenya', 'Male', 'Statistics as Topic'] | 6,651,215 | [['M01.060.406'], ['E05.318.740.225.500.375', 'I01.198.780.937.343', 'N04.452.910.099.500'], ['M01.686.754', 'N01.224.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.058.290.120.400'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
[Recurrent orbital complication by rhinosinusitis. A case report]. | Orbital infection is the most frequent complication of ethmoiditis. Recurrent periorbital cellulitis is a very rare complication of rhinosinusitis with only three reports in the literature describing this pathological process. This complication can be favored by an anatomical abnormality of the uncinate process or muco... | ['Abscess', 'Child, Preschool', 'Ethmoid Sinusitis', 'Humans', 'Male', 'Orbital Cellulitis', 'Recurrence', 'Rhinitis'] | 31,758,908 | [['C01.830.025', 'C23.550.470.756.100'], ['M01.060.406.448'], ['C01.748.749.267', 'C08.460.692.752.267', 'C08.730.749.267', 'C09.603.692.752.267'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.675.387', 'C17.300.185.500'], ['C23.550.291.937'], ['C01.748.674', 'C08.460.799', 'C08.730.674', 'C09.603.799']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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