Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Kenyan adults. | BACKGROUND: Heterologous prime boost immunization with chimpanzee adenovirus 63 (ChAd63) and Modified vaccinia Virus Ankara (MVA) vectored vaccines is a strategy recently shown to be capable of inducing strong cell mediated responses against several antigens from the malaria parasite. ChAd63-MVA expressing the Plasmodi... | ['Adenoviruses, Simian', 'Adult', 'Antigens, Protozoan', 'Gambia', 'Genetic Vectors', 'Humans', 'Immunization, Secondary', 'Interferon-gamma', 'Kenya', 'Malaria Vaccines', 'Malaria, Falciparum', 'Male', 'Middle Aged', 'Plasmodium falciparum', 'T-Lymphocytes', 'Vaccines, Synthetic', 'Vaccinia virus', 'Young Adult'] | 23,526,949 | [['B04.280.030.500.700'], ['M01.060.116'], ['D23.050.293'], ['Z01.058.290.190.300'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400.485', 'E05.478.550.550'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23... | ['Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Human lens membrane cation permeability increases with age. | Parallel studies of the ionic balance and membrane permeability characteristics of normal human lenses were carried out in three countries (USA, England and Italy). Similar age-related changes were found in each laboratory. The lens membrane potential and resistance declined markedly with age while internal Na+ and fre... | ['Adult', 'Aged', 'Aging', 'Biological Transport', 'Calcium', 'Cations', 'Cell Membrane Permeability', 'Humans', 'Lens, Crystalline', 'Membrane Potentials', 'Middle Aged', 'Potassium', 'Sodium'] | 2,759,800 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['G03.143'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.248.497.300'], ['G03.143.335', 'G04.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.060.500'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['M01.060.116.630']... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Phospholipid transfer protein destabilizes mouse atherosclerotic plaque. | OBJECTIVE: Phospholipid transfer protein (PLTP) accelerates the development of atherosclerosis in mouse models. We examined the role of PLTP in atherosclerotic plaque stability.APPROACH AND RESULTS: We prepared apolipoprotein E and PLTP double-knockout (PLTP(-/-)ApoE(-/-)) mice. PLTP deficiency significantly decreased ... | ['Animals', 'Apolipoproteins E', 'Apoptosis', 'Carotid Arteries', 'Carotid Stenosis', 'Caspase 3', 'Chemokines', 'Cytokines', 'Lipids', 'Macrophages', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Mice, Transgenic', 'Phospholipid Transfer Proteins', 'Plaque, Atherosclerotic', 'Reactive Oxygen Species', 'Rece... | 25,324,570 | [['B01.050'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['G04.146.954.035'], ['A07.015.114.186'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Radiobiological evaluation of breast cancer radiotherapy accounting for the effects of patient positioning and breathing in dose delivery. A meta analysis. | In breast cancer radiotherapy, significant discrepancies in dose delivery can contribute to underdosage of the tumor or overdosage of normal tissue, which is potentially related to a reduction of local tumor control and an increase of side effects. To study the impact of these factors in breast cancer radiotherapy, a m... | ['Algorithms', 'Breast Neoplasms', 'Female', 'Humans', 'Models, Theoretical', 'Patient Positioning', 'Radiometry', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Respiration'] | 22,775,337 | [['G17.035', 'L01.224.050'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['E02.760.670', 'N02.421.585.700'], ['E05.799'], ['E02.815.639'], ['E02.950.825', 'L01.313.500.750.100.710.600.608'], ['G09.772.705']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Metabolite profiling during cold acclimation of Lolium perenne genotypes distinct in the level of frost tolerance. | Abiotic stresses, including low temperature, can significantly reduce plant yielding. The knowledge on the molecular basis of stress tolerance could help to improve its level in species of relatively high importance to agriculture. Unfortunately, the complex research performed so far mainly on model species and also, t... | ['Acclimatization', 'Amino Acids', 'Carbohydrates', 'Cold Temperature', 'Gas Chromatography-Mass Spectrometry', 'Gene Expression Regulation, Plant', 'Genotype', 'Lolium', 'Metabolome', 'Principal Component Analysis'] | 26,025,228 | [['G07.025.133', 'G16.012.500.133'], ['D12.125'], ['D09'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G05.308.375'], ['G05.380'], ['B01.650.940.800.575.912.250.822.500'], ['G03.500... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The Effect of Human-Immunodeficiency Virus Status on Outcomes in Penetrating Abdominal Trauma: An Interim Analysis. | BACKGROUND: The purpose of this study was to determine whether the outcomes of hemodynamically stable patients undergoing exploratory laparotomy for penetrating abdominal trauma differed as a result of their HIV status.METHODS: This was an observational, prospective study from February 2016 to May 2017. All hemodynamic... | ['Abdominal Injuries', 'Acquired Immunodeficiency Syndrome', 'Adult', 'CD4 Lymphocyte Count', 'Female', 'HIV Seronegativity', 'HIV Seropositivity', 'Humans', 'Laparotomy', 'Length of Stay', 'Logistic Models', 'Male', 'Postoperative Complications', 'Prospective Studies', 'Treatment Outcome', 'Wounds, Penetrating'] | 29,387,958 | [['C26.017'], ['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Psychotherapists' vicarious traumatization during the COVID-19 pandemic. | During the COVID-19, psychotherapists are often exposed to traumatic material in their sessions, potentially leading to vicarious traumatization. We surveyed 339 therapists about their professional practices and experiences during the pandemic. Results showed that on average therapists experienced moderate levels of vi... | ['Adult', 'Aged', 'Aged, 80 and over', 'COVID-19', 'Coronavirus Infections', 'Cross-Sectional Studies', 'Empathy', 'Female', 'Health Personnel', 'Humans', 'Male', 'Middle Aged', 'Pandemics', 'Pneumonia, Viral', 'Psychological Trauma', 'Psychotherapy', 'Self Report', 'Young Adult'] | 32,478,559 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['C01.925.782.600.550.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Studies of immune functions of patients with systemic lupus erythematosus. Complement-dependent immunoglobulin M anti-thymus-derived cell antibodies preferentially inactivate suppressor cells. | Patients with systemic lupus erythematosus (SLE) produce excessive amounts of autoantibodies. It has also been demonstrated in several systems that such patients have a relative loss of suppressor thymus-derived (T) cells that inhibit the immune response. This loss of suppressor cells has been suggested as one of the c... | ['Adult', 'Autoantibodies', 'Complement System Proteins', 'Concanavalin A', 'Humans', 'Immunoglobulin M', 'Lupus Erythematosus, Systemic', 'Lymphocyte Activation', 'T-Lymphocytes'] | 312,810 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Survivin expression by metastatic melanoma predicts poor disease outcome in patients receiving adjuvant polyvalent vaccine. | Survivin and livin are members of the inhibitor of apoptosis protein (IAP) family. We hypothesized that elevated expression levels of these 2 IAP genes in resected advanced-stage metastatic melanoma lesions would be associated with poor disease outcome in patients receiving a polyvalent therapeutic cancer vaccine (Canv... | ['Adaptor Proteins, Signal Transducing', 'Adult', 'Aged', 'Cancer Vaccines', 'Combined Modality Therapy', 'Female', 'Gene Expression', 'Humans', 'Immunohistochemistry', 'Immunotherapy', 'Inhibitor of Apoptosis Proteins', 'Male', 'Melanoma', 'Microtubule-Associated Proteins', 'Middle Aged', 'Neoplasm Metastasis', 'Neopl... | 15,986,442 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['M01.060.116'], ['M01.060.116.100'], ['D20.215.894.200'], ['E02.186'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.1... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
The informative content of diagnostic tests: an economic analysis. | In medical literature the value of diagnostic tests is most of the time appreciated from their statistical properties (sensitivity and specificity) and from the prevalence of a given disease. In this paper we also take into account economic parameters such as the benefits and costs of the potential treatment under cons... | ['Biopsy, Needle', 'Clinical Laboratory Techniques', 'Cost-Benefit Analysis', 'Digoxin', 'Models, Theoretical', 'Probability'] | 6,427,932 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['E01.370.225', 'E05.200'], ['N03.219.151.125'], ['D04.210.500.155.580.130.500.436', 'D04.210.500.155.580.130.688', 'D09.408.180.261.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Shewanella alga bacteremia and associated cellulitis in a patient with multiple myeloma. | Shewanella alga is a gram-negative bacillus found in all types of water as well as in a variety of tainted food. It has rarely been associated with human disease, either in healthy or in immunocompromised patients. We report a 66-year-old man with a multiple myeloma who developed a cellulitis in both forearms in the co... | ['Aged', 'Bacteremia', 'Ceftazidime', 'Cellulitis', 'Disease-Free Survival', 'Forearm', 'Humans', 'Male', 'Multiple Myeloma', 'Shewanella'] | 12,243,559 | [['M01.060.116.100'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['D02.065.589.099.249.210.150', 'D02.886.665.074.210.150', 'D03.633.100.300.249.210.150'], ['C01.800.130', 'C01.830.200', 'C17.300.185', 'C23.550.470.756.200'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fort Polk Heart Smart Program. Part III: Assessment of dietary intake of military wives. | Dietary intake of military wives and factors that influence nutrition of military families were examined in 186 military wives--67% white, 18% black, 11% Hispanic, and 4% other. The ages ranged from 19 to 45 years (mean = 28.7 years). The observations show that 1.7 meals per day were shared by all family members. Due t... | ['Adult', 'Cardiovascular Diseases', 'Diet', 'Eating', 'Ethnic Groups', 'Family', 'Female', 'Health Promotion', 'Humans', 'Life Style', 'Louisiana', 'Middle Aged', 'Military Personnel'] | 8,502,394 | [['M01.060.116'], ['C14'], ['G07.203.650.240'], ['G07.203.650.283', 'G10.261.330'], ['M01.686.754', 'N01.224.317'], ['F01.829.263', 'I01.880.853.150'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458'], ['Z01.107.567.875.750.480'], ['M01.060.116.630'], ['M01.52... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The Chinese version of the Perceived Stress Questionnaire: development and validation amongst medical students and workers. | BACKGROUND: A valid and efficient stress measure is important for clinical and community settings. The objectives of this study were to translate the English version of the Perceived Stress Questionnaire (PSQ) into Chinese and to assess the psychometric properties of the Chinese version of the PSQ (C-PSQ). The C-PSQ ev... | ['Adult', 'China', 'Factor Analysis, Statistical', 'Female', 'Health Personnel', 'Humans', 'Male', 'Middle Aged', 'Quality of Life', 'Reproducibility of Results', 'Stress, Psychological', 'Students, Medical', 'Surveys and Questionnaires', 'Translations', 'Young Adult'] | 32,169,070 | [['M01.060.116'], ['Z01.252.474.164'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685',... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Enhancement of DMBA-induced mammary cancer in Wistar rats by unsaturated fat and cholestyramine. | Promotion of 7,12-dimethylbenzantracene (DMBA)-induced mammary cancer in Wistar rats, by diets containing unsaturated fat (USF) and unsaturated fat plus 4% cholestyramine (USF+ CHST) was compared to that in rats fed saturated fat (SF). The diets were fed for 100 or 200 days. Histologic examination of grossly normal mam... | ['9,10-Dimethyl-1,2-benzanthracene', 'Animals', 'Cholestyramine Resin', 'Dietary Fats', 'Drug Synergism', 'Fatty Acids, Unsaturated', 'Female', 'Mammary Neoplasms, Experimental', 'Rats', 'Rats, Inbred Strains'] | 2,979,798 | [['D02.455.426.559.847.149.301', 'D04.615.149.301'], ['B01.050'], ['D05.750.716.579.159', 'D25.720.716.579.159', 'J01.637.051.720.716.579.159'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['G07.690.773.968.477'], ['D10.251.355'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['B01.050.150.900.649.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The role of PKCæ in cord blood T-cell maturation towards Th1 cytokine profile and its epigenetic regulation by fish oil. | While immunodeficiency of immaturity of the neonate has been considered important as the basis for unusual susceptibility to infection, it has also been recognized that the ability to progress from an immature Th2 cytokine predominance to a Th1 profile has relevance in determining whether children will develop allergy,... | ['Acetylation', 'Analysis of Variance', 'Common Variable Immunodeficiency', 'Cytokines', 'Dietary Supplements', 'Disease Susceptibility', 'Epigenesis, Genetic', 'Fetal Blood', 'Fish Oils', 'Histones', 'Humans', 'Immunophenotyping', 'Infant, Newborn', 'Interferon-gamma', 'Interleukin-13', 'Protein Kinase C', 'RNA, Small... | 28,159,873 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C20.673.330'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.203.300.456', 'J02.500.456'], ['C23.550.291.687', 'G07.100.250'], ['G05.308.203'], ['A12.207.152.200', 'A15.145.300', '... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
SLAC1 is required for plant guard cell S-type anion channel function in stomatal signalling. | Stomatal pores, formed by two surrounding guard cells in the epidermis of plant leaves, allow influx of atmospheric carbon dioxide in exchange for transpirational water loss. Stomata also restrict the entry of ozone--an important air pollutant that has an increasingly negative impact on crop yields, and thus global car... | ['Abscisic Acid', 'Animals', 'Anions', 'Arabidopsis', 'Arabidopsis Proteins', 'Calcium', 'Darkness', 'Environment', 'Humidity', 'Hydrogen Peroxide', 'Ion Channel Gating', 'Ion Channels', 'Ion Transport', 'Light', 'Membrane Proteins', 'Nitric Oxide', 'Onions', 'Oocytes', 'Ozone', 'Plant Leaves', 'Plant Stomata', 'Signal... | 18,305,484 | [['D02.241.223.268.034', 'D02.455.326.271.665.202.061', 'D02.455.426.392.368.367.379.249.024', 'D02.455.849.131.061', 'D02.455.849.765.521.500'], ['B01.050'], ['D01.248.497.158'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G01.590.540.233'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Early functional improvement after a modified ligament reconstruction tendon interposition arthroplasty for thumb basal joint arthritis. | Many modifications to trapeziectomy have been proposed for the treatment of thumb basal joint arthritis. Their final outcomes have been discussed intensively, whereas functional changes in the early post-operative period have not been fully documented. The purpose of the present study is to evaluate an early functional... | ['Aged', 'Arthroplasty', 'Carpometacarpal Joints', 'Female', 'Hand Strength', 'Humans', 'Ligaments, Articular', 'Middle Aged', 'Movement', 'Osteoarthritis', 'Pain Measurement', 'Tendons', 'Thumb', 'Trapezium Bone'] | 19,378,359 | [['M01.060.116.100'], ['E04.555.110', 'E04.680.101'], ['A02.835.583.405.200'], ['E01.370.600.425.500', 'G11.427.560.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.513.514', 'A02.835.583.512', 'A10.165.669.514'], ['M01.060.116.630'], ['G07.568', 'G11.427.410'], ['C05.550.114.606', 'C05.799.613'], ['E01.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The clinical course of fatal aneurysm rupture of the base of the skull]. | At the Institut of Pathology and the Institut of Forensic Medicine at the Charit? Clinics of the Humboldt-University Berlin from 1979 to 1984 took place 13,622 necropsies. Among them were 75 cases of fatal ruptures of intracranial aneurysms. This paper gives a description of the resulting subarachnoid hemorrhages (SAH)... | ['Adult', 'Aged', 'Circle of Willis', 'Female', 'Follow-Up Studies', 'Glasgow Coma Scale', 'Humans', 'Intracranial Aneurysm', 'Male', 'Middle Aged', 'Rupture, Spontaneous', 'Subarachnoid Hemorrhage'] | 2,624,027 | [['M01.060.116'], ['M01.060.116.100'], ['A07.015.114.228.351'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.318.308.940.968.875.250', 'E05.944.500', 'N04.452.859.564.800.250', 'N05.715.360.300.715.500.800.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Safety and efficacy of dedicated guidewire and microcatheter technology for chronic total coronary occlusion revascularization: principal results of the Asahi Intecc Chronic Total Occlusion Study. | BACKGROUND: Limited study has detailed the procedural outcomes and utilization of contemporary coronary guidewires and microcatheters designed for chronic total occlusion (CTO) percutaneous revascularization and with application of modern techniques.PATIENTS AND METHODS: A prospective, multicenter, single-arm trial was... | ['Aged', 'Cardiac Catheterization', 'Cardiac Catheters', 'Chronic Disease', 'Coronary Angiography', 'Coronary Occlusion', 'Equipment Design', 'Female', 'Hospital Mortality', 'Humans', 'Male', 'Middle Aged', 'Miniaturization', 'Myocardial Infarction', 'Percutaneous Coronary Intervention', 'Prospective Studies', 'Risk Fa... | 30,308,588 | [['M01.060.116.100'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E07.132.750.249'], ['C23.550.291.500'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.272', 'C14.907.585.250.272'], ['E05.320'], ['E05.318.308.985.550.400', 'N01.224.935.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Critical brain regions for tool-related and imitative actions: a componential analysis. | Numerous functional neuroimaging studies suggest that widespread bilateral parietal, temporal, and frontal regions are involved in tool-related and pantomimed gesture performance, but the role of these regions in specific aspects of gestural tasks remains unclear. In the largest prospective study of apraxia-related les... | ['Adult', 'Aged', 'Aged, 80 and over', 'Brain', 'Brain Mapping', 'Female', 'Functional Laterality', 'Gestures', 'Humans', 'Imitative Behavior', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Posture', 'Prospective Studies', 'Psychomotor Performance', 'Stroke', 'Tool Use Behavior'] | 24,776,969 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.830.297.425', 'G11.561.225.425'], ['F01.145.209.530.538.445'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.510'], ['E01.370.350.825.500'], ['M0... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Wallerian degeneration in the optic nerve of the wabbler-lethal (wl/wl) mouse. | Optic nerve pathology was studied in C57BL/6J wabbler-lethal (wl/wl) and control (+/+) mice at postnatal age of 4 weeks (P28). Qualitative light and ultrastructural pathology in wl/wl animals conformed to the criteria of primary axonal (Wallerian) degeneration. Most optic nerve axons in mutant animals appeared normal, ... | ['Animals', 'Axonal Transport', 'Axons', 'Body Weight', 'Mice', 'Mice, Inbred C57BL', 'Mice, Neurologic Mutants', 'Myelin Sheath', 'Oligodendroglia', 'Optic Nerve', 'Wallerian Degeneration'] | 1,382,814 | [['B01.050'], ['G03.143.355.040', 'G04.392.040', 'G11.561.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
N-terminal-probrain natriuretic peptide as a biomarker of moderate to severe bronchopulmonary dysplasia in preterm infants: A prospective observational study. | OBJECTIVE: N-terminal-probrain natriuretic peptide (NT-proBNP) is a marker of hemodynamically significant patent ductus arteriosus (HsPDA) in preterm infants. In this study, we assessed whether NT-proBNP levels could predict the risk of moderate to severe bronchopulmonary dysplasia (BPD) and/or death.METHODS: This was ... | ['Biomarkers', 'Bronchopulmonary Dysplasia', 'Enterocolitis, Necrotizing', 'Female', 'Humans', 'Hypertension, Pulmonary', 'Infant', 'Infant, Newborn', 'Infant, Premature', 'Infant, Very Low Birth Weight', 'Intracranial Hemorrhages', 'Male', 'Natriuretic Peptide, Brain', 'Peptide Fragments', 'Prospective Studies', 'Resp... | 29,790,673 | [['D23.101'], ['C08.381.520.750.500', 'C16.614.521.125'], ['C06.405.205.596.700', 'C06.405.469.363.700'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['M01.060.703'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['M01.060.703.520.460.600'], ['C10.228.140.300.535', 'C14.907.253.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impact of gas(less) laparoscopy and laparotomy on peritoneal tumor growth and abdominal wall metastases. | OBJECTIVE: A tumor model in the rat was used to study peritoneal tumor growth and abdominal wall metastases after carbon dioxide (CO2) pneumoperitoneum, gasless laparoscopy, and laparotomy.SUMMARY BACKGROUND DATA: The role of laparoscopic resection of cancer is under debate. Insufflation of the peritoneal cavity with C... | ['Abdominal Neoplasms', 'Analysis of Variance', 'Animals', 'Laparoscopy', 'Laparotomy', 'Male', 'Neoplasm Seeding', 'Peritoneal Neoplasms', 'Rats'] | 8,968,224 | [['C04.588.033'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E04.406'], ['C04.697.650.830', 'C23.550.727.650.830'], ['C04.588.033.513', 'C04.588.274.780', 'C06.301.780', 'C06.844.620'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Standards, Options and Recommendations 2005 for a good practice in enteral nutrition in oncology (summary report.)]. | CONTEXT: The "Standards, Options and Recommendations" (SOR) project, which started in 1993, is a collaboration between the French Federation of Cancer Centers (FNCLCC), the 20 French Regional Cancer Centers, and specialists from French public universities, general hospitals and private clinics. The main objective is th... | ['Enteral Nutrition', 'Humans', 'Medical Oncology'] | 16,886,237 | [['E02.421.360', 'E02.642.500.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.429.515']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Social adaptation of mentally retarded adults in community settings: a social-ecological approach. | Evidence regarding the social networks of mentally retarded adults in community settings is reviewed. These networks appear to be widespread and consist primarily of peers. The social ecology of community settings is a critical factor in the development and maintenance of these networks. Given the considerable importan... | ['Adult', 'Ecology', 'Humans', 'Intellectual Disability', 'Intelligence', 'Interpersonal Relations', 'Peer Group', 'Residential Facilities', 'Social Adjustment', 'Social Support'] | 6,670,868 | [['M01.060.116'], ['H01.158.273.248', 'H01.277.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['F01.752.543'], ['F01.829.401'], ['F01.829.316.483'], ['J03.775', 'N02.278.825'], ['F01.145.813.621'], ['I01.880.853.500.600']] | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 |
[The method of treatment choice for the abdominal wall hernia]. | Experience of treatment of 975 patients with postoperative and recurrent abdominal wall hernia (AWH) and of 1473 patients with inguinal hernia was summarized. Intraoperative classification of Shevrel and Rets for AWH and of Gilbert and Rutkov for inguinal hernia were applied. The conventional methods of plasty, using l... | ['Abdominal Muscles', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Hernia, Inguinal', 'Humans', 'Male', 'Middle Aged', 'Surgical Procedures, Operative'] | 11,944,300 | [['A02.633.567.050'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.300.707.374.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04']] | ['Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mouse Parabrachial Neurons Signal a Relationship between Bitter Taste and Nociceptive Stimuli. | Taste and somatosensation both mediate protective behaviors. Bitter taste guides avoidance of ingestion of toxins while pain sensations, such as noxious heat, signal adverse conditions to ward off harm. Although brain pathways for taste and somatosensation are typically studied independently, prior data suggest that th... | ['Action Potentials', 'Animals', 'Capsaicin', 'Cycloheximide', 'Female', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mustard Plant', 'Nociception', 'Parabrachial Nucleus', 'Plant Oils', 'Quinine', 'Sensory Receptor Cells', 'Taste', 'Taste Perception', 'Transient Receptor Potential Channels'] | 30,606,758 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['D02.065.690.500', 'D02.455.326.271.690.222', 'D02.455.426.559.389.657.166.099', 'D03.132.760.200', 'D10.251.355.325.190'], ['D03.383.621.808.240'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A functional variant in ST2 gene is associated with risk of hypertension via interfering MiR-202-3p. | Recent studies have suggested that interleukin 1 receptor-like 1 (ST2) plays a critical role in pathogenesis of several cardiovascular disease conditions. In this study, we examined association of 13 single nucleotide polymorphisms (SNPs) of ST2 gene with essential hypertension (EH) risk in 1151 patients with EH and 11... | ['Aged', 'Essential Hypertension', 'Female', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Interleukin-1 Receptor-Like 1 Protein', 'Male', 'MicroRNAs', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Risk Factors'] | 28,121,058 | [['M01.060.116.100'], ['C14.907.489.165'], ['E05.393.385'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.750.705.852.420.300.375'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['M01.060.116.630'], ['G05.365.795.598'], ['E0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Histidine-114 at subsites E and F can explain the characteristic enzymatic activity of guinea hen egg-white lysozyme. | The courses of the reaction catalyzed by guinea hen egg-white lysozyme (GHL), in which Asn113 and Arg114 at subsites E and F in hen egg-white lysozyme (HEL) are replaced by Lys and His, respectively, was studied with the substrate N-acetylglucosamine pentamer, (GlcNAc)5. Although GHL was found to retain the main-chain ... | ['Acetylglucosamine', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Animals', 'Arginine', 'Binding Sites', 'Catalysis', 'Chickens', 'Egg White', 'Glycosylation', 'Histidine', 'Hydrogen Bonding', 'Kinetics', 'Molecular Sequence Data', 'Muramidase', 'Mutagenesis, Site-Directed', 'Protein Binding', 'Sequence Alignmen... | 12,723,601 | [['D09.067.342.531.050'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G02.111.570.120'], ['G02.130'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G07.203.300.470.700', 'J02.500.470.700... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Cardiac involvement in polymyositis. | Sixteen cases of polymyositis (PM) were treated at the Central Hospital, Jyv?skyl?. Features of cardiac involvement were observed in 11 cases (69%). The heart diseases which developed or worsened after the onset of PM were grouped as follows: (1) Sole disturbance of conduction--one case, (2) congestive heart failure--f... | ['Adolescent', 'Adult', 'Aged', 'Arrhythmias, Cardiac', 'Cardiomyopathies', 'Coronary Disease', 'Female', 'Heart Failure', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Myocardium', 'Myositis', 'Prognosis'] | 734,377 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C14.280.067', 'C23.550.073'], ['C14.280.238'], ['C14.280.647.250', 'C14.907.585.250'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The valine anticodon and valylatability of Peanut clump virus RNAs are not essential but provide a modest competitive advantage in plants. | The role of valine aminoacylation of the two genomic RNAs of Peanut clump virus (PCV) was studied by comparing the amplification in vivo of RNAs with GAC, GDeltaC, or CCA anticodons in the tRNA-like structure (TLS) present at the 3' end of each viral RNA. The PCV RNA1 TLS of isolate PCV2 possesses a GAC anticodon and i... | ['Anticodon', 'Base Sequence', 'Blotting, Northern', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Mutation', 'Plants, Toxic', 'Protoplasts', 'RNA Viruses', 'RNA, Transfer, Amino Acyl', 'RNA, Transfer, Val', 'RNA, Viral', 'Sequence Analysis, RNA', 'Tobacco', 'Valine'] | 10,954,573 | [['D13.444.735.757.286', 'G05.360.335.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['L01.453.245.667'], ['E05.393.420.601.575'], ['G05.365.590'], ['B01.650.660'], ['A11.789'], ['B04.820'], ['D12.125.780', 'D13.444.735.757.715'], ['D13.444.735.7... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mixed bis(thiosemicarbazone) ligands for the preparation of copper radiopharmaceuticals: synthesis and evaluation of tetradentate ligands containing two dissimilar thiosemicarbazone functions. | A series of four "mixed" bis(thiosemicarbazone) keto aldehyde derivatives containing dissimilar thiosemicarbazone functions were synthesized and evaluated as ligands for preparation of radiocopper-labeled radiopharmaceuticals. The pyruvaldehyde-based mixed bis(thiosemicarbazone) ligands CH3C[=NNHC(S)NH2]CH[=NNHC(S)NHMe... | ['Animals', 'Copper', 'Dogs', 'Humans', 'Radiopharmaceuticals', 'Rats', 'Thiosemicarbazones', 'Tissue Distribution', 'Ultrafiltration'] | 9,016,338 | [['B01.050'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.259.843', 'D27.505.519.871', 'D27.720.470.410.650'], ['B01.050.150.900.649.313.992.635.505.700'], ['D02.845.746.703', 'D02.886.803'], ['G03.787... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An unusual foreign body presenting in the nasopharynx. | A 24-year-old male, who sustained gross facial injuries as a result of a motor accident, presented six months later on account of unilateral nasal obstruction and foul discharge. A diagnosis of right maxillary sinusitis was made and a right Caldwell-Luc operation was performed. At operation, a piece of wood was discove... | ['Accidents, Traffic', 'Adult', 'Foreign Bodies', 'Humans', 'Male', 'Nasopharynx', 'Wood'] | 3,411,225 | [['N06.850.135.392'], ['M01.060.116'], ['C26.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.623.557', 'A14.724.557'], ['A18.450.500.500', 'J01.637.241.900']] | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Iron limitation effects on nitrogen-fixing organisms with possible implications for cyanobacterial blooms. | Cyanobacteria-dominated harmful algal blooms are increasing in occurrence. Many of the taxa contributing to these blooms are capable of fixing atmospheric nitrogen and should be favored under conditions of low nitrogen availability. Yet, synthesizing nitrogenase, the enzyme responsible for nitrogen fixation, is energet... | ['Bacterial Proteins', 'Cyanobacteria', 'Iron', 'Nitrogen', 'Nitrogen Fixation', 'Nitrogenase', 'Phosphorus', 'Rivers'] | 29,566,225 | [['D12.776.097'], ['B03.280', 'B03.440.475.100'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D01.268.604', 'D01.362.625'], ['G02.111.071.630', 'G02.111.587.750', 'G02.607.560.750', 'G03.087.630', 'G06.625', 'G16.500.768.600'], ['D08.811.682.647'], ['D01.268.666'], ['G01.311.750', 'G16.500.275.280.650'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Histamine-induced hypocalcemia in the rat. | The effect of histamine and betazole hydrochloride (Histalog) on serum calcium homeostasis in the rat was studied in these experiments. Either histamine base, histamine phosphate, betazole, or the appropriate control solution was injected intravenously into fasted, anesthetized 80-100 g male rats. Venous blood was coll... | ['Animals', 'Betazole', 'Calcium', 'Gastrins', 'Histamine', 'Homeostasis', 'Male', 'Rats', 'Time Factors'] | 1,250,153 | [['B01.050'], ['D03.383.129.539.100'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D06.472.317.413', 'D06.472.699.280', 'D12.644.400.320', 'D12.644.548.280', 'D12.776.631.650.320'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['G07.410'], ['B01.050.150.900.649.313.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The characteristics of changes of indicators of hypophyseal-thyroid system and lipid metabolism in adolescents of different ethnic groups]. | The girls and boys (the ethnic tofs) residing in the village of Alykdjer of Nijneudinsky district of Irkutsk oblast have been examined. The Irkutsk girls and boys (the Caucasians) made the comparison groups. In tof boys the activation of hypophyseal-thyroid system and activity increase of lipoprotein spectrum of blood ... | ['Adaptation, Physiological', 'Adolescent', 'Body Mass Index', 'Child', 'Ethnic Groups', 'Female', 'Humans', 'Lipids', 'Male', 'Pituitary Gland', 'Thyroid Gland', 'alpha-Tocopherol'] | 22,624,457 | [['G07.025', 'G16.012.500'], ['M01.060.057'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406'], ['M01.686.754', 'N01.224.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10'], ['A06.300.747', 'A06.688.357.750', 'A08.186.211.180.497.352.435.500', 'A0... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Echocardiographic findings in patients on maintenance hemodialysis substituted with recombinant human erythropoietin. | Cardiomegaly and impaired myocardial function are frequent in patients on maintenance hemodialysis. One important reason is probably severe renal anemia. Substitution with recombinant human erythropoietin (rhEPO) results in long-term correction of renal anemia. We investigated the changes in cardiac function under rhEP... | ['Anemia', 'Cardiomegaly', 'Echocardiography', 'Erythropoietin', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Myocardial Contraction', 'Recombinant Proteins', 'Renal Dialysis'] | 2,521,587 | [['C15.378.071'], ['C14.280.195', 'C23.300.775.250'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['D12.644.276.374.410.240.150', 'D12.776.395.240.150', 'D12.776.467.374.410.240.150', 'D23.529.374.410.240.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
C-terminal truncations of a thermostable Bacillus stearothermophilus alpha-amylase. | A series of truncated proteins from a thermostable Bacillus stearothermophilus alpha-amylase was prepared to study the importance of the extension in the C-terminus compared with other liquefying Bacillus alpha-amylases. The mutations introducing new translation termination sites shortened the 515 amino acid residue-lo... | ['Amino Acid Sequence', 'Bacillus', 'Enzyme Stability', 'Geobacillus stearothermophilus', 'Kinetics', 'Models, Molecular', 'Molecular Sequence Data', 'Mutagenesis', 'Peptide Fragments', 'Protein Engineering', 'Sequence Deletion', 'Sequence Homology, Amino Acid', 'Temperature', 'alpha-Amylases'] | 7,855,141 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['E05.916.360', 'G02.111.700.500'], ['B03.300.390.400.158.400.400', 'B03.353.500.100.400.400', 'B03.510.100.100.400.400', 'B03.510.415.400.158.400... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Sorptive removal of trivalent and hexavalent chromium from binary aqueous solutions by composite alginate-goethite beads. | In this study, the removal of hexavalent and trivalent chromium ions from binary aqueous solutions by composite alginate-goethite beads was investigated in a batch mode. Equilibrium sorption experiments were carried out at different temperatures and pH values. The data were correlated with Langmuir and Freundlich equat... | ['Absorption', 'Alginates', 'Chromium', 'Diffusion', 'Hydrogen-Ion Concentration', 'Iron Compounds', 'Kinetics', 'Minerals', 'Solutions', 'Temperature', 'Water', 'Water Pollutants, Chemical', 'Water Purification'] | 16,233,908 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['D09.698.068'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['G01.202', 'G02.196'], ['G02.300'], ['D01.490'], ['G01.374.661', 'G02.111.490'], ['D01.578'], ['D26.776'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', ... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The HPA-axis and immune function in burnout. | Burnout results from chronic work stress. Its complaints may be related to HPA-axis disturbances or changes in immune function. In our studies the salivary cortisol awakening response, day-curve, and the suppressed level after dexamethasone intake were not different in a burned-out group compared to a control group. No... | ['Burnout, Professional', 'Cytokines', 'Dehydroepiandrosterone Sulfate', 'Dexamethasone', 'Humans', 'Hydrocortisone', 'Hypothalamo-Hypophyseal System', 'Pituitary-Adrenal System', 'Saliva'] | 18,037,026 | [['C24.580.500', 'F01.145.126.990.367.500', 'F02.830.900.333.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D04.210.500.054.079.429.625.300', 'D04.210.500.578.502.400.300', 'D06.472.040.502.400.300', 'D06.472.334.851.968.952.300'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['B01.050.150.9... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aggression in adolescents: the role of social support and personality. | A study was conducted to determine the degree to which social support and personality predict the use of reasoning and aggression by adolescents to resolve interpersonal conflict. Although all adolescents appeared to use reasoning to resolve conflict, those with less social support and those exhibiting a forceful perso... | ['Adolescent', 'Aggression', 'Conflict, Psychological', 'Female', 'Humans', 'Individuality', 'Interpersonal Relations', 'Male', 'Personality Development', 'Personality Tests', 'Social Environment', 'Social Support', 'Violence'] | 2,346,896 | [['M01.060.057'], ['F01.145.126.125', 'F01.145.813.045'], ['F01.658.209'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.488'], ['F01.829.401'], ['F01.752.747'], ['F04.711.647'], ['I01.880.853.500'], ['I01.880.853.500.600'], ['I01.198.240.856', 'I01.880.735.900']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
A novel locus for autosomal dominant non-syndromic hearing loss, DFNA31, maps to chromosome 6p21.3. | BACKGROUND: Non-syndromic hearing loss is the most genetically heterogeneous trait known in humans. To date, 51 loci for autosomal dominant non-syndromic sensorineural hearing loss (NSSHL) have been identified by linkage analysis.OBJECTIVE: To investigate the genes involved in a Dutch family with NSSHL.METHODS: Linkage... | ['Age of Onset', 'Child', 'Child, Preschool', 'Chromosome Mapping', 'Chromosomes, Human, Pair 6', 'Female', 'Genes, Dominant', 'Genetic Linkage', 'Genetic Markers', 'Hearing Loss, Sensorineural', 'Humans', 'Male', 'Pedigree', 'Syndrome'] | 14,729,819 | [['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.406'], ['M01.060.406.448'], ['E05.393.183'], ['A11.284.187.520.300.325.330', 'G05.360.162.520.300.325.330'], ['G05.360.340.024.340.240', 'G05.420.320'], ['G05.348'], ['D23.101.387', 'G05.695.450'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.888.592... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Multidisciplinary therapy for peritoneal dissemination using peritonectomy]. | An aggressive approach to peritoneal dissemination involves peritonectomy procedures combined with preoperative intraperitoneal chemotherapy, intraoperative chemo-hyperthermia, and postoperative systemic chemotherapy. We have been performing multimodal therapy consisting of peritonectomy plus perioperative chemotherapy... | ['Colonic Neoplasms', 'Combined Modality Therapy', 'Female', 'Humans', 'Hyperthermia, Induced', 'Mesothelioma', 'Ovarian Neoplasms', 'Peritoneal Neoplasms', 'Peritoneum', 'Stomach Neoplasms'] | 12,484,031 | [['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.565'], ['C04.557.470.035.510', 'C04.557.470.660.510'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The first molecular detection of Clostridium perfringens from pneumonic cases associated with foot and mouth disease in cattle and buffalo in Egypt. | Panting syndrome and respiratory infection have been recorded in complicated cases of foot and mouth disease (FMD) in cattle. However, investigations on the causative agents of respiratory disease in such cases are scarce. In this study, 30 animals (13 buffalo and 17 cattle) suffering from respiratory distress associat... | ['Animals', 'Bacterial Toxins', 'Buffaloes', 'Cattle', 'Cattle Diseases', 'Clostridium Infections', 'Clostridium perfringens', 'Egypt', 'Foot-and-Mouth Disease', 'Multiplex Polymerase Chain Reaction', 'Pneumonia'] | 30,488,175 | [['B01.050'], ['D23.946.123'], ['B01.050.150.900.649.313.500.380.135'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['C01.150.252.410.222'], ['B03.300.390.400.200.575', 'B03.353.625.375.500.575', 'B03.510.415.400.200.575'], ['Z01.058.266.317'], ['C01.925.782.687.484', 'C22.380'], ['E05.393.620.500.487'], ['C0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Role of RFRP-3 in the development of cold stress-induced polycystic ovary phenotype in rats | RFamide-related peptide (RFRP-3) is a regulator of GnRH secretion from the brain, but it can also act in human ovary to influence steroidogenesis. We aimed to study the putative local role of RFRP-3 in the ovary and its potential participation in the development of a polycystic ovary phenotype induced by chronic sympat... | ['Animals', 'Cold Temperature', 'Female', 'Hypothalamic Hormones', 'Hypothalamus', 'Ovary', 'Polycystic Ovary Syndrome', 'Progesterone', 'Rats, Sprague-Dawley', 'Receptors, Neuropeptide', 'Stress, Physiological', 'Testosterone'] | 30,307,156 | [['B01.050'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D06.472.699.327', 'D12.644.400.400', 'D12.644.548.365', 'D12.776.631.650.405'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['A05.360.319.114.630', 'A05.360.57... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of animal models for predicting bronchodilator efficacy in man. | In vitro and in vivo models of bronchodilation were compared to assess their relative usefulness for predicting clinical efficacy. Drugs studied were isoproterenol, isoetharine, salbutamol, hexoprenaline, terbutaline, ephedrine and aminophylline. In vitro preparations were guinea pig perfused lung, tracheal strip and ... | ['Administration, Oral', 'Aerosols', 'Albuterol', 'Aminophylline', 'Animals', 'Bronchodilator Agents', 'Dogs', 'Dose-Response Relationship, Drug', 'Ephedrine', 'Female', 'Guinea Pigs', 'Heart Atria', 'Heart Rate', 'Hexoprenaline', 'In Vitro Techniques', 'Injections, Intravenous', 'Isoetharine', 'Isoproterenol', 'Lung',... | 1,190,917 | [['E02.319.267.100'], ['D20.280.055', 'D26.255.165.055'], ['D02.033.100.291.057', 'D02.092.063.291.057', 'D02.092.471.683.061'], ['D02.092.782.258.368.050', 'D03.633.100.759.758.824.751.075', 'D26.310.048'], ['B01.050'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['B01.050.150.900.649.313.750.250.216.200']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increases in dentin-bond strength if doubling application time of an acetone-containing one-step adhesive. | This study investigated the microtensile bond strength (microTBS) of a one-step self-etching adhesive to human dentin and bovine enamel following different bonding treatments. Occlusal portions of human molars and labial surfaces of bovine incisors were ground flat to provide uniform dentin and enamel surfaces, respect... | ['Acetone', 'Acid Etching, Dental', 'Animals', 'Cattle', 'Composite Resins', 'Dental Bonding', 'Dental Enamel', 'Dentin', 'Dentin-Bonding Agents', 'Humans', 'Humidity', 'Materials Testing', 'Methacrylates', 'Oxidants', 'Phosphoric Acids', 'Sodium Hypochlorite', 'Solvents', 'Stress, Mechanical', 'Temperature', 'Tensile ... | 17,427,821 | [['D02.522.064'], ['E06.931.475.111'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.095'], ['A14.549.167.900.255'], ['A14.549.167.900.280'], ['D25.339.291.300', 'J01.637.051.339.29... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Triphalangeal thumb and brachy-ectrodactyly syndrome. Confirmation of autosomal dominant inheritance. | Two patients with triphalangeal thumbs-ectrodactyly syndrome are described. The first case is a 4-year-old female with triphalangeal thumbs, preaxial polydactyly with rudimentary polydactyly of the 3rd finger of the right hand and ectro-syndactyly of feet. Her stillborn sister had triphalangeal thumbs and ectrodactyly ... | ['Abnormalities, Multiple', 'Child, Preschool', 'Female', 'Genes, Dominant', 'Humans', 'Infant, Newborn', 'Pedigree', 'Radiography', 'Syndrome', 'Thumb', 'Toes'] | 3,568,429 | [['C16.131.077'], ['M01.060.406.448'], ['G05.360.340.024.340.240', 'G05.420.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E05.393.673'], ['E01.370.350.700'], ['C23.550.288.500'], ['A01.378.800.667.430.705'], ['A01.378.610.250.300.792']] | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adenovirus-mediated gene transfer of glial cell line-derived neurotrophic factor prevents motor neuron loss of transgenic model mice for amyotrophic lateral sclerosis. | Effects of adenovirus-mediated gene transfer of glial cell line-derived neurotrophic factor (GDNF) were studied in transgenic (Tg) mice model for amyotrophic lateral sclerosis (ALS). Adenoviral vector containing GDNF gene (Ad-GDNF), E. coli lacZ (Ad-LacZ), or vehicle was injected once a week from 35 weeks of age into t... | ['Adenoviridae', 'Amyotrophic Lateral Sclerosis', 'Animals', 'Cell Death', 'Gene Transfer Techniques', 'Genetic Therapy', 'Genetic Vectors', 'Glial Cell Line-Derived Neurotrophic Factor', 'Mice', 'Mice, Transgenic', 'Motor Neurons', 'Nerve Growth Factors', 'Neuroglia'] | 12,101,392 | [['B04.280.030'], ['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['B01.050'], ['G04.146'], ['E05.393.350'], ['E02.095.301', 'E05.393.420.301'], ['G05.360.337'], ['D12.644.276.860.381.500', 'D12.776.467.860.381.500', 'D12.776.631.600.381.500', 'D23.529.850.381.500'],... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A way to avoid using precious metals: the application of high-surface activated carbon for the synthesis of isoindoles via the Diels-Alder reaction of 2H-pyran-2-ones. | The application of activated carbon (Darco KB) for the acceleration and direction of the transformation of various 2H-pyran-2-ones with N-substituted maleimides toward isoindole derivatives through the reaction sequence cycloaddition/elimination/dehydrogenation is described. In this reaction, the catalyst mainly influe... | ['Carbon', 'Cyclization', 'Isoindoles', 'Metals', 'Molecular Structure', 'Pyrones', 'Stereoisomerism'] | 22,352,708 | [['D01.268.150'], ['G02.111.180', 'G02.607.133', 'G03.208'], ['D03.633.100.513'], ['D01.552'], ['G02.111.570', 'G02.466'], ['D03.383.663.718'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The electrochemical H+ gradient of platelet secretory alpha-granules. Contribution of a H+ pump and a Donnan potential. | Experiments were performed to determine the internal pH and membrane potential of platelet alpha-granules. Fluorescence microscopy showed accumulation of weak bases, indicative of an acidic interior, inside secretory vesicles in intact platelets and in isolated alpha-granules. Weak base uptake was pH-dependent and NH+4... | ['Ammonia', 'Animals', 'Blood Platelets', 'Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone', 'Cytoplasmic Granules', 'Intracellular Membranes', 'Membrane Potentials', 'Microscopy, Fluorescence', 'Nigericin', 'Osmolar Concentration', 'Rubidium', 'Swine', 'Valinomycin'] | 6,863,268 | [['D01.362.075', 'D01.625.050'], ['B01.050'], ['A11.118.188', 'A15.145.229.188'], ['D02.442.288.220', 'D02.626.270'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['A11.284.149.450', 'A11.284.835.514'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['E01.370.350.515.458', 'E05.595.458'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Paclitaxel-releasing mesenchymal stromal cells inhibit the growth of multiple myeloma cells in a dynamic 3D culture system. | Multiple myeloma is an aggressive tumour able to suppress osteoblastogenesis probably mediated by bone marrow mesenchymal stromal cells (BM-MSCs) that can also support plasma cell growth/survival. The use of MSCs for multiple myeloma therapy is a controversial topic because of the contradictory results on the capacity ... | ['Antineoplastic Agents', 'Cell Line, Tumor', 'Cell Proliferation', 'Culture Media, Conditioned', 'Drug Resistance, Neoplasm', 'Drug Tolerance', 'Humans', 'Mesenchymal Stem Cells', 'Multiple Myeloma', 'Paclitaxel', 'Spheroids, Cellular', 'Tumor Cells, Cultured'] | 27,283,119 | [['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D27.720.470.305.250', 'E07.206.250'], ['G07.690.773.984.395'], ['G07.690.773.992'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.830.500', 'A11.872.590.500'], ['C04.557.595.500', 'C14.907.454.460', 'C15... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of wildfire on floral display size and pollinator community reduce outcrossing rate in a plant with a mixed mating system. | PREMISE OF THE STUDY: Wildfire changes the demography, morphology, and behavior of plants, and may alter the pollinator community. Such trait changes may drastically alter the outcome of pollination mutualisms on plants; however, the direct role of fire on these mutualisms is poorly known.METHODS: Following a pair of f... | ['Animals', 'Bees', 'California', 'Flowers', 'Phenotype', 'Plant Physiological Phenomena', 'Plants', 'Pollen', 'Pollination', 'Reproduction', 'Wildfires'] | 30,047,984 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.387'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['A18.024.249.500'], ['G05.695'], ['G15'], ['B01.650'], ['A18.024.249.500.249.500'], ['G08.686.784.743', 'G15.776'], ['G08.686.784'], ['G01.311.988', 'N06.230.100.230.925', 'N06.230.216.875']] | ['Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Bioaccumulation of polychlorinated biphenyls in mullet fish in a former ship dismantling harbour, a contaminated estuary, and nearby coastal fish farms. | This study investigated the bioaccumulation of polychlorinated biphenyls (PCBs) toward mullet fish (Liza macrolepis) living in former PCB contaminated areas, the Ann-Ping harbour and the Er-Jen estuary, and fish farms located near the above two areas in 2003. The PCB body burdens of collected fish samples are proportio... | ['Animals', 'Aquaculture', 'Chromatography, Gas', 'Environmental Monitoring', 'Fishes', 'Geography', 'Lipids', 'Metallurgy', 'Polychlorinated Biphenyls', 'Seasons', 'Seawater', 'Smegmamorpha', 'Taiwan', 'Water Pollutants, Chemical'] | 16,257,016 | [['B01.050'], ['J01.040.168'], ['E05.196.181.349'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.493'], ['H01.277.500'], ['D10'], ['J01.576.655.875.400'], ['D02.309.750', 'D02.455.426.559.389.185.698', 'D02.455.526.439.773'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['G16.... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Thin-layer chromatography/direct analysis in real time time-of-flight mass spectrometry and isotope dilution to analyze organophosphorus insecticides in fatty foods. | To assess food safety emergencies caused by highly hazardous chemical-tainted foods, simultaneous analysis of organophosphorus insecticides in fatty foods such as precooked foods was conducted using thin-layer chromatography/direct analysis in real time time-of-flight mass spectrometry (TLC/DART-TOFMS) and isotope dilu... | ['Chromatography, High Pressure Liquid', 'Chromatography, Thin Layer', 'Fats', 'Food Analysis', 'Indicator Dilution Techniques', 'Insecticides', 'Isotopes', 'Mass Spectrometry', 'Phosphorus', 'Time Factors'] | 25,454,149 | [['E05.196.181.400.300'], ['E05.196.181.400.537'], ['D10.212'], ['E05.362', 'J01.576.423.850.100'], ['E05.484'], ['D27.720.031.700.491', 'D27.888.723.491'], ['D01.496'], ['E05.196.566'], ['D01.268.666'], ['G01.910.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Randomized efficacy trials of long-acting oxytetracycline in neonatal pigs. | Prophylactic efficacy of 100 mg of long-acting oxytetracycline (OTC) given IM to neonatal pigs within 12 hours of birth was evaluated in a swine herd. The herd had a history of increased neonatal mortality, diarrhea, foot abscess, and arthritis in nursing pigs. Two trials were conducted in which liters and individual p... | ['Abscess', 'Animals', 'Animals, Newborn', 'Arthritis, Infectious', 'Bacterial Infections', 'Diarrhea', 'Female', 'Foot Diseases', 'Male', 'Oxytetracycline', 'Prognosis', 'Random Allocation', 'Swine', 'Swine Diseases', 'Weight Gain'] | 2,925,481 | [['C01.830.025', 'C23.550.470.756.100'], ['B01.050'], ['B01.050.050.282'], ['C01.100', 'C05.550.114.099'], ['C01.150.252'], ['C23.888.821.214'], ['C05.360', 'C17.800.321'], ['D02.455.426.559.847.562.900.600', 'D04.615.562.900.600'], ['E01.789'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Nonunion of a fractured scaphoid tubercle. | A case of nonunion of an avulsed scaphoid tubercle fragment is reported. The fragment became surrounded with a rim of calcification and ossification. After 3 1/2 years follow-up the fragment had migrated to the carpal tunnel simulating the appearance of an accessory ossicle. | ['Adult', 'Calcinosis', 'Carpal Bones', 'Follow-Up Studies', 'Fractures, Ununited', 'Humans', 'Male', 'Radiography', 'Time Factors'] | 2,324,458 | [['M01.060.116'], ['C18.452.174.130'], ['A02.835.232.087.319.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C26.404.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['G01.910.857']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Management of severe lower abdominal or inguinal pain in high-performance athletes. PAIN (Performing Athletes with Abdominal or Inguinal Neuromuscular Pain Study Group). | The purpose of this study was to gain insight into the pathophysiologic processes of severe lower-abdominal or inguinal pain in high-performance athletes. We evaluated 276 patients; 175 underwent pelvic floor repairs. Of the 157 athletes who had not undergone previous surgery, 124 (79%) participated at a professional o... | ['Abdominal Pain', 'Adult', 'Athletic Injuries', 'Female', 'Humans', 'Inguinal Canal', 'Male', 'Muscle, Skeletal', 'Pelvic Floor', 'Pelvic Pain', 'Physical Therapy Modalities', 'Syndrome'] | 10,653,536 | [['C23.888.592.612.054', 'C23.888.821.030'], ['M01.060.116'], ['C26.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.923.047.412'], ['A02.633.567', 'A10.690.552.500'], ['A01.923.600.600', 'A02.633.567.050.750'], ['C23.888.592.612.944'], ['E02.779', 'E02.831.535'], ['C23.550.288.500']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of xeroradiographic image quality. | A theory of edge enhancement has been developed to describe xeroradiographic images of linear step objects. The theory is shown to give an accurate description of the relationship between edge enhancement, subject contrast, radiation exposure, selenium charging potential and developer bias potential. An optimal transmi... | ['Mammography', 'Mathematics', 'Physical Phenomena', 'Physics', 'Radiographic Image Enhancement', 'Xeroradiography'] | 935,409 | [['E01.370.350.700.500'], ['H01.548'], ['G01'], ['H01.671'], ['E01.370.350.600.350.700', 'E01.370.350.700.700', 'L01.224.308.380.600'], ['E01.370.350.700.975']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Nightguard vital bleaching of tetracycline-stained teeth: 90 months post treatment. | PURPOSE: The purpose of this longitudinal whitening study was to determine the stability, post-treatment side effects, and patient satisfaction at 90 months post treatment after 6 months of active treatment of tetracycline-stained teeth with 10% carbamide peroxide.MATERIALS AND METHODS: Fifteen of 21 participants enrol... | ['Adult', 'Anti-Bacterial Agents', 'Carbamide Peroxide', 'Dental Devices, Home Care', 'Drug Combinations', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Oxidants', 'Patient Satisfaction', 'Peroxides', 'Tetracycline', 'Tooth Bleaching', 'Tooth Discoloration', 'Urea'] | 12,859,112 | [['M01.060.116'], ['D27.505.954.122.085'], ['D01.248.497.158.685.750.318', 'D01.339.431.374.318', 'D01.650.550.750.300', 'D02.065.950.278', 'D02.389.338.154'], ['E06.186.250', 'E06.761.726.292', 'E07.222.250'], ['D26.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.50... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Decreased fetal cardiac performance in the first trimester correlates with hyperglycemia in pregestational maternal diabetes. | OBJECTIVE: In-vitro animal studies suggest that high glucose levels impair fetal cardiac function early in gestation. We aimed to study whether evidence of first-trimester myocardial dysfunction can be detected in fetuses of women with pregestational diabetes mellitus.METHODS: Women with diabetes mellitus underwent fet... | ['Adult', 'Diabetes Mellitus, Type 1', 'Echocardiography, Doppler', 'Female', 'Fetal Heart', 'Gestational Age', 'Glycated Hemoglobin A', 'Humans', 'Hyperglycemia', 'Pregnancy', 'Pregnancy Outcome', 'Pregnancy Trimester, First', 'Pregnancy in Diabetics', 'Prospective Studies', 'Ultrasonography, Prenatal', 'Umbilical Art... | 21,538,641 | [['M01.060.116'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['A07.541.278', 'A16.378.303'], ['G07.345.500.325.235.968', 'G08.686.320'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.3... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Native amphibian larvae exhibit higher upper thermal limits but lower performance than their introduced predator Gambusia affinis. | Information on the thermal limits and physiology of ectothermic amphibians is crucial to our understanding of their ecology in the natural environment, particularly with predicted global changes in climate. We documented the thermal limits of larvae of three amphibian species native to Hong Kong, and their introduced, ... | ['Animals', 'Anura', 'Body Temperature Regulation', 'Cold Temperature', 'Cyprinodontiformes', 'Hot Temperature', 'Larva', 'Thermotolerance'] | 30,975,413 | [['B01.050'], ['B01.050.150.900.090.180'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['B01.050.150.900.493.850.280'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Change in the distribution of alpha-tocopherol stereoisomers in rats after intravenous administration. | Synthetic alpha-tocopherol (alpha-Toc) contains equal amounts of eight different stereoisomers arising from three chiral centers in the phytyl tail. Of these, the four stereoisomers with the 2R configuration are generally more active than their corresponding 2S-isomers. We investigated the change in distribution of alp... | ['Adrenal Glands', 'Animals', 'Erythrocytes', 'Injections, Intravenous', 'Kidney', 'Liver', 'Male', 'Myocardium', 'Rats', 'Rats, Sprague-Dawley', 'Stereoisomerism', 'Time Factors', 'Tissue Distribution', 'Vitamin E'] | 7,787,294 | [['A06.300.071'], ['B01.050'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['A05.810.453'], ['A03.620'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G02.607.445.6... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Polymorphic molecular markers from anonymous nuclear DNA for genetic analysis of populations. | A simple method is presented for developing polymorphic, anonymous DNA markers suitable for population genetic studies. Anonymous DNA fragments are screened for sequence variability using a common mutation detection technique (single strand conformation polymorphism analysis; SSCP) and locus-specific PCR primers are de... | ['Alleles', 'Animals', 'Base Sequence', 'DNA', 'DNA Primers', 'Genetic Markers', 'Genetic Techniques', 'Genetic Variation', 'Genetics, Population', 'Heterozygote', 'Introns', 'Molecular Sequence Data', 'Oncorhynchus mykiss', 'Polymorphism, Genetic', 'Polymorphism, Single-Stranded Conformational', 'Random Amplified Poly... | 9,131,810 | [['G05.360.340.024.340.030'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D23.101.387', 'G05.695.450'], ['E05.393'], ['G05.365'], ['H01.158.273.343.335'], ['G05.380.383'], ['G05.360.340.024.220.400', 'G05.360.340.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Evaluation of the liquid-chromatographic resolution of indenoindolic racemic compounds on three protein-based chiral stationary phases. | Three liquid-chromatography columns, containing immobilized proteins as chiral stationary phases (CSPs) were investigated for the direct separation of enantiomers of racemic indenoindolic compounds. By using an experimental design the effects of column temperature, pH, ionic strength, and type and concentration of orga... | ['Chromatography, Liquid', 'Hydrogen-Ion Concentration', 'Indicators and Reagents', 'Indoles', 'Orosomucoid', 'Ovomucin', 'Proteins', 'Serum Albumin, Bovine', 'Solvents', 'Stereoisomerism', 'Temperature'] | 9,696,569 | [['E05.196.181.400'], ['G02.300'], ['D27.720.470.410'], ['D03.633.100.473'], ['D12.776.124.050.600', 'D12.776.124.790.106.640', 'D12.776.377.715.085.640', 'D12.776.395.560.742'], ['D12.776.256.159.157.675', 'D12.776.290.675', 'D12.776.395.560.760'], ['D12.776'], ['D12.776.034.841.540', 'D12.776.124.727.875'], ['D27.720... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Why do we have to review our experience in managing cases with idiopathic fistula-in-ano regularly? | "Why do we have to review our experience in managing idiopathic fistula-in-ano regularly?" In order to answer this apparently simple question, we reviewed our clinical and surgical cases and most important relevant literature to find a rational and scientific answer. It would appear that whatever method you adopt in fi... | ['Disease Management', 'Humans', 'Postoperative Complications', 'Rectal Fistula', 'Recurrence', 'Treatment Outcome'] | 21,876,617 | [['N04.590.607'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.767'], ['C06.267.550.600', 'C06.405.469.471.600', 'C06.405.469.860.752', 'C23.300.575.185.550.600'], ['C23.550.291.937'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Spontaneous expulsion of an intravesical bullet. | Gunshot wounds of the pelvis are not uncommon. Penetrating injuries of the bladder are usually documented by means of a cystogram. The patient reported here was shot with a small caliber bullet. No extravasation was demonstrated. The authors caution that not all penetrating injuries to the bladder will demonstrate extr... | ['Adult', 'Foreign Bodies', 'Humans', 'Male', 'Radiography', 'Urinary Bladder', 'Urination', 'Wounds, Gunshot'] | 9,257,512 | [['M01.060.116'], ['C26.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['A05.810.890'], ['G08.852.880'], ['C26.986.900']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Different isoforms of secreted aspartyl proteinases (Sap) are expressed by Candida albicans during oral and cutaneous candidosis in vivo. | Distinct isoforms of secreted aspartyl proteinases (Sap) of Candida albicans are important virulence factors for different types of candidosis. Predominant expression of Sap1-3 has been shown to be crucial for superficial infections in experimental mucosal and cutaneous candidosis, whereas Sap4-6 might be important for... | ['Adult', 'Aged', 'Antibodies, Fungal', 'Aspartic Acid Endopeptidases', 'Candida albicans', 'Candidiasis, Cutaneous', 'Candidiasis, Oral', 'Female', 'Humans', 'Immunohistochemistry', 'Isoenzymes', 'Male', 'Microscopy, Immunoelectron', 'Middle Aged', 'Virulence'] | 11,478,679 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.179', 'D12.776.124.790.651.114.179', 'D12.776.377.715.548.114.179'], ['D08.811.277.656.074.500', 'D08.811.277.656.300.048'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['C01.150.703.160.132', 'C01.150.703.302.105', 'C01.800... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Acquired blepharoptosis secondary to essential blepharospasm. | We treated four patients with essential blepharospasm, receiving botulinum A toxin, in whom, although they had no preexisting blepharoptosis, a concurrent bilateral acquired blepharoptosis developed. Since the blepharoptosis did not improve after the period of time during which the effects of botulinum A toxin would ha... | ['Aged', 'Aged, 80 and over', 'Blepharoptosis', 'Blepharospasm', 'Botulinum Toxins', 'Eyelids', 'Female', 'Humans', 'Male', 'Middle Aged', 'Muscles'] | 8,233,320 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C11.338.204'], ['C11.338.250'], ['D08.811.277.656.300.480.153', 'D08.811.277.656.675.374.153', 'D12.776.097.156', 'D23.946.123.179'], ['A01.456.505.420.504', 'A09.371.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633', 'A10.690']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Idiopathic restrictive cardiomyopathy. Description of 4 cases]. | The clinical and instrumental characteristics of four patients suffering from idiopathic restrictive cardiomyopathy are analysed. Patients were diagnosed following hemodynamic and histological tests. The major clinical symptom was cardiac decompensation and/or hyperkinetic or hypokinetic (3rd degree BAV) supraventricul... | ['Adult', 'Cardiomyopathy, Restrictive', 'Echocardiography, Doppler', 'Electrocardiography', 'Female', 'Heart Transplantation', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged'] | 2,092,233 | [['M01.060.116'], ['C14.280.238.160'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Abnormal brain and muscle energy metabolism shown by 31P-MRS in familial hemiplegic migraine. | Familial hemiplegic migraine (FHM) is a rare autosomal dominant disorder of unknown pathogenesis characterized by migraine and transitory hemiplegic attacks. We describe a kindred fulfilling the diagnostic criteria for FHM in which: (1) brain phosphorus magnetic resonance spectroscopy (31P-MRS) showed a reduced phospho... | ['Adolescent', 'Adult', 'Biopsy', 'Brain', 'Case-Control Studies', 'Energy Metabolism', 'Female', 'Hemiplegia', 'Humans', 'Magnetic Resonance Spectroscopy', 'Male', 'Middle Aged', 'Migraine Disorders', 'Mitochondria', 'Muscle, Skeletal', 'Pedigree', 'Phosphorus', 'Reference Values'] | 7,608,738 | [['M01.060.057'], ['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A08.186.211'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G03.295'], ['C10.597.622.295', 'C23.888.592.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Early dynamics of hepatitis C virus in the circulation of chimpanzees with experimental infection. | Two chimpanzees were inoculated with hepatitis C virus (HCV) and followed on a daily basis for 12 days. HCV RNA became detectable in their sera on day 5 by polymerase chain reaction with the detection limit of 10(2) copies/ml. Based on an exponential growth observed until 8 or 9 days after inoculation in their sera, th... | ['Animals', 'Disease Models, Animal', 'Hepacivirus', 'Hepatitis C', 'Kinetics', 'Pan troglodytes', 'RNA, Viral', 'Reverse Transcriptase Polymerase Chain Reaction', 'Viremia'] | 15,812,184 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649.313.988.400.112.400.620'], ['D13.444.735.828'], ['E05.393.620.500.725'], ['C01.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide Hydrolase. | Isothermal titration calorimetry (ITC) is conventionally used to acquire thermodynamic data for biological interactions. In recent years, ITC has emerged as a powerful tool to characterize enzyme kinetics. In this study, we have adapted a single-injection method (SIM) to study the kinetics of human soluble epoxide hydr... | ['Adamantane', 'Biocatalysis', 'Calorimetry', 'Enzyme Assays', 'Epoxide Hydrolases', 'Epoxy Compounds', 'Fatty Acids', 'Flow Injection Analysis', 'Humans', 'Hydrolysis', 'Kinetics', 'Lauric Acids', 'Lipid Metabolism', 'Recombinant Proteins', 'Solutions', 'Substrate Specificity'] | 31,660,733 | [['D02.455.426.100.050', 'D02.455.426.392.368.075'], ['G02.111.086', 'G02.130.500', 'G03.105'], ['E05.196.131'], ['E05.196.427'], ['D08.811.277.340'], ['D02.355.291.411'], ['D10.251'], ['E05.196.460'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.380'], ['G01.374.661', 'G02.111.490'], ['D10.251.500'], ['G03.4... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical aspects of heparin induced thrombocytopenia]. | Heparin induced thrombocytopenia has remained the major complication of therapy or prophylaxis with heparin. Although low molecular weight heparins seem to confer much lesser chance to induce thrombocytopenia, the danger is still considerable, and the fatal outcome is not rare. A lot of new data have been published abo... | ['Heparin', 'Humans', 'Predictive Value of Tests', 'Prognosis', 'Thrombocytopenia', 'Thrombosis'] | 10,461,446 | [['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E01.789'], ['C15.378.140.855'], ['C14.907.355.830']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Wartime military deployment and increased pediatric mental and behavioral health complaints. | BACKGROUND: Children of military personnel face stress when a parent deploys.OBJECTIVE: Our goal was to determine the effect of parental military deployment on the relative rate of outpatient visits for mental and behavioral health disorders in children aged 3 to 8 years.METHODS: This was a retrospective cohort study. ... | ['Anxiety Disorders', 'Child', 'Child Behavior Disorders', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Male', 'Mental Disorders', 'Military Personnel', 'Parents', 'Retrospective Studies', 'Risk Factors', 'Stress, Psychological', 'United States', 'Warfare'] | 21,059,715 | [['F03.080'], ['M01.060.406'], ['F03.625.141'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Purification and characterization of a novel inhibitor of the proliferation of hepatic stellate cells. | An inhibitor of the proliferation of hepatic stellate cells (HSC) was purified from rat liver by a combination of gel filtration and ion exchange chromatography. The molecular mass of this non-arginase growth inhibitory factor (NAGIF) was determined to be 38 kDa by sodium dodecyl sulfate-polyacrylamide gel electrophore... | ['Amino Acid Sequence', 'Animals', 'Cattle', 'Cell Division', 'Cell Line', 'Cells, Cultured', 'Dose-Response Relationship, Drug', 'Glycoproteins', 'Growth Inhibitors', 'Intercellular Signaling Peptides and Proteins', 'Liver', 'Male', 'Mice', 'Molecular Sequence Data', 'Rats', 'Rats, Sprague-Dawley', 'Tumor Cells, Cultu... | 10,731,662 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['A11.251'], ['G07.690.773.875', 'G07.690.936.500'], ['D09.400.430', 'D12.776.395'], ['D27.505.696.377.450'], ['D12.644.276', 'D12... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The effect of inhibition of Ca2+-independent phospholipase A2 on chemotherapeutic-induced death and phospholipid profiles in renal cells. | We demonstrate that cells derived from primary cultures of rabbit proximal tubules (RPTC), human embryonic kidney (HEK293) and human kidney carcinomas (Caki-1) express microsomal Ca(2+)-independent phospholipase A(2) (iPLA(2)gamma) and cytosolic Ca(2+)-independent phospholipase A(2) (iPLA(2)beta). Inhibition of iPLA(2)... | ['Animals', 'Antineoplastic Agents', 'Calcium', 'Cell Death', 'Cell Line', 'Cisplatin', 'Female', 'Group VI Phospholipases A2', 'Humans', 'Kidney', 'Phospholipases A', 'Phospholipases A2', 'Phospholipids', 'Rabbits', 'Vincristine'] | 16,226,224 | [['B01.050'], ['D27.505.954.248'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.146'], ['A11.251.210'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D08.811.277.352.100.680.750.937.300.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['D08.811.277.352.100.680.750'], ['D08.811... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Insight into the radical mechanism of phycocyanobilin-ferredoxin oxidoreductase (PcyA) revealed by X-ray crystallography and biochemical measurements. | The X-ray crystal structure of the substrate-free form of phycocyanobilin (PCB)-ferredoxin oxidoreductase (PcyA; EC 1.3.7.5) from the cyanobacterium Nostoc sp. PCC7120 has been solved at 2.5 A resolution. A comparative analysis of this structure with those recently reported for substrate-bound and substrate-free forms ... | ['Binding Sites', 'Crystallization', 'Crystallography, X-Ray', 'Models, Chemical', 'Mutagenesis, Site-Directed', 'Oxidoreductases', 'Protein Folding'] | 17,279,614 | [['G02.111.570.120'], ['E05.196.300', 'G02.171'], ['E05.196.309.742.225'], ['E05.599.495'], ['E05.393.420.601.575'], ['D08.811.682'], ['G01.154.651', 'G02.111.688']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Area-Level Predictors of Medication Nonadherence Among US Medicaid Beneficiaries With Lupus: A Multilevel Study. | OBJECTIVE: Adherence to hydroxychloroquine (HCQ) treatment in patients with systemic lupus erythematous (SLE) is suboptimal. Although individual-level factors, including younger age and non-white race/ethnicity, have been implicated, contextual factors have not been explored. The aim of this study was to investigate th... | ['Adolescent', 'Adult', 'Antirheumatic Agents', 'Female', 'Humans', 'Hydroxychloroquine', 'Insurance Benefits', 'Lupus Erythematosus, Systemic', 'Male', 'Medicaid', 'Medication Adherence', 'Middle Aged', 'Prevalence', 'Residence Characteristics', 'Risk Assessment', 'Risk Factors', 'Social Class', 'United States', 'Vuln... | 30,055,088 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.329'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.810.050.180.350'], ['N03.219.521.576.130'], ['C17.300.480', 'C20.111.590'], ['N03.219.521.346.506.564.655', 'N03.706.615.693'], ['F01.100.150.750.500.600.500', 'F01.145.488.887.500.600.500', 'N05.300.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
In vitro biomechanical comparison of a 5-hole 4.5 mm locking compression plate and 5-hole 4.5 mm dynamic compression plate for equine proximal interphalangeal joint arthrodesis. | OBJECTIVE: To compare the biomechanical properties of a 5-hole 4.5 mm narrow locking compression plate (LCP) and 5-hole 4.5 mm narrow dynamic compression plate (DCP) for equine proximal interphalangeal (PIP) joint arthrodesis.STUDY DESIGN: Experimental mechanical study.ANIMALS: Cadaveric adult equine forelimbs (n = 6 p... | ['Animals', 'Arthrodesis', 'Biomechanical Phenomena', 'Bone Plates', 'Cadaver', 'Forelimb', 'Horses', 'In Vitro Techniques', 'Mechanical Phenomena', 'Random Allocation', 'Toe Joint'] | 24,512,440 | [['B01.050'], ['E04.555.100'], ['G01.154.090', 'G01.374.089'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['C23.550.260.224'], ['A13.395'], ['B01.050.150.900.649.313.984.235.472'], ['E05.481'], ['G01.374'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.70... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Eliciting patients' preferences for outpatient treatment of febrile neutropenia: a discrete choice experiment. | BACKGROUND: Studies have demonstrated that patients at low risk for febrile neutropenia (FN) complications can be treated safely and effectively at home. Information on patient preferences for outpatient treatment of this condition will help to optimize health care delivery to these patients. The purpose of this study ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Caregivers', 'Female', 'Fever', 'Financing, Personal', 'Health Care Costs', 'Health Care Surveys', 'Home Care Services, Hospital-Based', 'Humans', 'Logistic Models', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Multivariate An... | 22,684,150 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['C23.888.119.344'], ['N03.219.559'], ['N03.219.151.400', 'N05.300.375'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Evaluating general and occupational morbidity on mining enterprises of Kazakhstan]. | Evaluating risks of occupational and occupationally mediated diseases is a main parameter in further social and hygienic monitoring of work conditions and health state among mining industry workers. | ['Catchment Area, Health', 'Health Status', 'Humans', 'Incidence', 'Kazakhstan', 'Mining', 'Occupational Diseases', 'Prevalence', 'Sick Leave'] | 18,396,521 | [['N01.224.791.200', 'N03.349.650.095', 'N06.850.505.400.800.200'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['Z01.252.100.420', 'Z01.542.931.4... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Neuronal tissue-specific ribonucleoprotein complex formation on SOD1 mRNA: alterations by ALS SOD1 mutations. | Amyotrophic lateral sclerosis (ALS) is a fatal disease of unknown etiology. Mutations in copper/zinc superoxide dismutase (SOD1) are the most commonly associated genetic abnormality. Given that SOD1 is ubiquitously expressed, the exclusive vulnerability of motor neurons is one of the most puzzling issues in ALS researc... | ['Humans', 'Motor Neuron Disease', 'Mutation', 'Neurons', 'RNA', 'RNA Probes', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'Ribonucleoproteins', 'Superoxide Dismutase', 'Superoxide Dismutase-1', 'Transcription, Genetic'] | 16,730,180 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.574.562', 'C10.668.467'], ['G05.365.590'], ['A08.675', 'A11.671'], ['D13.444.735'], ['D13.444.600.723', 'D27.505.259.750.600.825', 'D27.720.470.530.600.825'], ['D13.444.735.544'], ['E05.393.620.500.725'], ['D12.776.157.725.500', 'D12.776.664.962.500'], ['D08.811.6... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aluminum-induced alterations in [3H]ouabain binding and ATP hydrolysis catalyzed by the rat brain synaptosomal (Na(+)+K+)-ATPase. | The (Na(+)+K+)-ATPase is responsible for maintenance of the ionic milieu of cells. The objective of this study is to investigate the effect of aluminum, an ion implicated in several neurological disorders, on ATP hydrolysis catalyzed by the rat brain synaptosomal (Na(+)+K+)-ATPase and on the binding of [3H]ouabain to t... | ['Adenosine Triphosphate', 'Aluminum', 'Animals', 'Brain', 'Hydrolysis', 'Kinetics', 'Magnesium', 'Male', 'Ouabain', 'Protein Binding', 'Rats', 'Rats, Sprague-Dawley', 'Sodium-Potassium-Exchanging ATPase', 'Synaptosomes'] | 7,916,767 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D01.268.557.050', 'D01.552.547.050'], ['B01.050'], ['A08.186.211'], ['G02.380'], ['G01.374.661', 'G02.111.490'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['D04.210.500.155.580.130.750.600', 'D09.408.180.810.600'], ['G02.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anatomic total shoulder arthroplasty for patients receiving workers' compensation. | BACKGROUND: Studies have demonstrated that receiving workers' compensation (WC) benefits can be a negative predictor of outcomes after orthopedic procedures. This study compares postoperative outcomes of anatomic total shoulder arthroplasty (TSA) between patients receiving WC benefits and a control group that did not.M... | ['Adult', 'Aged', 'Arthroplasty, Replacement', 'Case-Control Studies', 'Cohort Studies', 'Follow-Up Studies', 'Humans', 'Male', 'Massachusetts', 'Middle Aged', 'Patient Outcome Assessment', 'Retrospective Studies', 'Return to Work', 'Shoulder Joint', 'Visual Analog Scale', "Workers' Compensation"] | 26,159,842 | [['M01.060.116'], ['M01.060.116.100'], ['E04.555.110.110', 'E04.650.110', 'E04.680.101.110'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Triacylglycerol kinetics in endotoxic rats with suppressed lipoprotein lipase activity. | Hypertriglyceridemia observed in animals after bacterial endotoxin administration and some forms of sepsis can result from increased hepatic triacylglycerol (TG) output or decreased TG clearance by extrahepatic tissues. To differentiate between these two possibilities, TG and free fatty acid (FFA) kinetics were determi... | ['Animals', 'Endotoxins', 'Fatty Acids, Nonesterified', 'Kinetics', 'Lipoprotein Lipase', 'Male', 'Rats', 'Rats, Inbred Strains', 'Triglycerides'] | 3,605,334 | [['B01.050'], ['D23.946.123.329'], ['D10.251.310'], ['G01.374.661', 'G02.111.490'], ['D08.811.277.352.100.430'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D10.351.801']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Fluidity of hepatic microsomal membrane and its relation with aging]. | The effect of aging on hepatic microsomal membrane phospholipid composition was studied composition was studied in both young (2 months) and mature (6 months) Wistar rats. When total microsomal phospholipid content was analysed the aged group showed a significant increment (73%). Microsomal phospholipid pattern also sh... | ['Aging', 'Animals', 'Body Weight', 'Male', 'Membrane Fluidity', 'Membrane Lipids', 'Microsomes, Liver', 'Organ Size', 'Phospholipids', 'Rats', 'Rats, Wistar'] | 1,300,853 | [['G07.345.124'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G01.154.500', 'G02.111.550', 'G04.570'], ['D10.570'], ['A11.284.835.540.541'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690'], ['D10... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Visual and motor functions in graphically gifted savants. | Savant artists represent a conundrum to our understanding of the nature of high level specific talents as well as to the concept of general intellectual impairment. In the present paper, we are particularly concerned with the relationship between general perceptual-motor functions in relation to drawing aptitude. Drawi... | ['Adolescent', 'Adult', 'Aptitude', 'Art', 'Autistic Disorder', 'Depth Perception', 'Discrimination Learning', 'Female', 'Field Dependence-Independence', 'Humans', 'Intelligence', 'Male', 'Mental Recall', 'Motor Skills', 'Neuropsychological Tests', 'Orientation', 'Pattern Recognition, Visual', 'Problem Solving', 'Psych... | 7,991,749 | [['M01.060.057'], ['M01.060.116'], ['F02.784.629.131'], ['K01.093'], ['F03.625.164.113.500'], ['F02.463.593.200', 'F02.463.593.778.255'], ['F02.463.425.280'], ['F02.463.593.343'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.543'], ['F02.463.425.540.641'], ['F02.808.260'], ['F04.711.513'], ['F01.058.577',... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Influence of mitochondria on phospholipid synthesis in preparations from rat liver. | 1. The addition of mitochondria to an incubation system containing the soluble and microsomal fractions of rat liver enhances severalfold the incorporation of each of ethanolamine, phosphorylethanolamine and CDP-ethanolamine into phosphatidylethanolamine. 2. In the presence of microsomal, mitochondrial and soluble frac... | ['Animals', 'Calcium', 'Carbon Radioisotopes', 'Cytosine Nucleotides', 'Electron Transport Complex IV', 'Ethanolamines', 'Glucose-6-Phosphatase', 'In Vitro Techniques', 'Kinetics', 'Magnesium', 'Microsomes, Liver', 'Mitochondria, Liver', 'Phosphatidylethanolamines', 'Rats', 'Subcellular Fractions'] | 4,360,711 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['D03.383.742.686.246', 'D13.695.740.246', 'D13.695.827.232'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Controversies in the fluid management of post-traumatic lung disease. | The appropriate intravenous therapy for injured patients is controversial. Use of colloid-containing solutions has been advocated in an attempt to maintain intravascular colloid osmotic pressure, minimize pulmonary oedema and draw fluid out of areas of contused lung. Studies of animals with lymph fistulas in the lung d... | ['Albumins', 'Capillary Permeability', 'Colloids', 'Crystalloid Solutions', 'Fluid Therapy', 'Humans', 'Isotonic Solutions', 'Lung Diseases', 'Plasma Substitutes', 'Shock, Hemorrhagic', 'Thoracic Injuries'] | 3,770,929 | [['D12.776.034'], ['G03.143.330', 'G09.330.165'], ['D20.280', 'D26.255.165'], ['D26.776.498.500'], ['E02.319.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.776.498'], ['C08.381'], ['D27.505.954.502.140.500'], ['C23.550.414.980', 'C23.550.835.650'], ['C26.891']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An in vitro model of anoxic-induced damage in mouse brain. | An in vitro model of anoxic-induced brain damage was developed to help elucidate the biochemical basis of cell damage due to reduced oxygen availability. Mouse forebrain slices were preincubated under various conditions (treatment incubation). The effects of this treatment incubation on [14C]acetylcholine (ACh) and 14C... | ['Acetylcholine', 'Animals', 'Brain', 'Calcium', 'Carbon Dioxide', 'Disease Models, Animal', 'Glucose', 'Hypoxia, Brain', 'In Vitro Techniques', 'Male', 'Mice'] | 3,130,584 | [['D02.092.211.111'], ['B01.050'], ['A08.186.211'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D09.947.875.359.448'], ['C10.228.140.624', 'C23.888.852.079.797'], ['E05.481'], ['B01.050.150.900.649.313.992.635... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Heart Failure Hospitalisations in the Hunter New England Area Over 10 years. A Changing Trend. | BACKGROUND: Heart failure carries a major burden on our health system, mainly related to the high rate of hospital admission. An understanding of the recent trends in heart failure hospitalisation is essential to the future allocation of health resources. Our aim is to analyse the temporal trends in heart failure hospi... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Australia', 'Female', 'Heart Failure', 'Hospitalization', 'Humans', 'Male', 'Retrospective Studies', 'Rural Population', 'Sex Factors', 'Urban Population'] | 27,916,591 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.639.100', 'Z01.678.100.373'], ['C14.280.434'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.... | ['Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Interferon-gamma and interleukin-4 gene polymorphisms in Caucasian idiopathic inflammatory myopathy patients in UK. | OBJECTIVE: To determine whether interferon-gamma (IFN-gamma) and interleukin-4 (IL-4) genes confer susceptibility for the idiopathic inflammatory myopathies (IIMs).METHODS: A large cross-sectional study of UK caucasian adults with polymyositis (PM, n = 101), dermatomyositis (DM, n = 94) and myositis overlapping with a ... | ['Adult', 'Case-Control Studies', 'Cross-Sectional Studies', 'Dermatomyositis', 'European Continental Ancestry Group', 'Gene Frequency', 'Genetic Markers', 'Genetic Predisposition to Disease', 'HLA Antigens', 'Humans', 'Interferon-gamma', 'Interleukin-4', 'Linkage Disequilibrium', 'Microsatellite Repeats', 'Myositis', ... | 17,405,833 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C05.651.594.819.500', 'C10.668.491.562.575.500', 'C17.300.250', 'C17.800.185'], ['M01.686.508.400'], ['G05.330'], ['D23.101.387', 'G05.695.450... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Personalized Exposure Control Using Adaptive Metering and Reinforcement Learning. | We propose a reinforcement learning approach for real-time exposure control of a mobile camera that is personalizable. Our approach is based on Markov Decision Process (MDP). In the camera viewfinder or live preview mode, given the current frame, our system predicts the change in exposure so as to optimize the trade-of... | ['Databases, Factual', 'Humans', 'Image Processing, Computer-Assisted', 'Lighting', 'Markov Chains', 'Neural Networks, Computer', 'Photography', 'Semantics'] | 30,113,896 | [['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['N06.230.150.410'], ['E05.318.740.600.500', 'E05.318.740.996.500', 'G17.830.500', 'N05.715.360.750.625.500', 'N05.715.360.750.770.500', 'N06.850.520.830.600.500', 'N06.850.520.830.996.500'], ['G17.485... | ['Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Chondroitin sulfate promotes activation of cathepsin K. | Cathepsin K (CatK), a major lysosomal collagenase produced by osteoclasts, plays an important role in bone resorption. Evidence exists that the collagenase activity of CatK is promoted by chondroitin sulfate (CS), a sulfated glycosaminoglycan. This study examines the role of CS in facilitating CatK activation. We have ... | ['Cathepsin K', 'Chondroitin Sulfates', 'Enzyme Activation', 'HEK293 Cells', 'Humans', 'Protein Processing, Post-Translational'] | 24,958,728 | [['D08.811.277.656.224.405', 'D08.811.277.656.262.500.156', 'D08.811.277.656.300.200.156'], ['D09.698.373.200.300'], ['G02.111.263', 'G03.328'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.660.871.790.600', 'G02.111.691.600', 'G03.734.871.790.600', 'G05.308.670.600... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gene fusions to the ptsM/pel locus of Escherichia coli. | We have constructed gene fusions between ptsM/pel and lacZ. These fusions affect both phenotypes assigned to the ptsM/pel locus (at 40 min), namely, no growth on mannose or glucosamine and inhibition of the penetration of bacteriophage lambda DNA, as well as that of other lambdoid phages such as Hy-2. Since the lacZ ge... | ['Bacteriophage lambda', 'Chromosome Mapping', 'Escherichia coli', 'Genes', 'Genes, Bacterial', 'Genotype', 'Operon', 'Phenotype', 'beta-Galactosidase'] | 3,162,078 | [['B04.123.150.800.230', 'B04.123.205.230', 'B04.280.090.800.230'], ['E05.393.183'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.380'], ['G05.360.340.024.686', 'G05.360.340.358.207.500'], ['... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Occupational dermatoses among foresters. | The incidence of occupational dermatoses among the forest workers of a timber company has been investigated. In the survey 73.69% of the occupational dermatoses observed were contact dermatitis, predominantly due to sawdust and sap. Insect bites, mycotic infections and staphylococcal and streptococcal infections were s... | ['Adult', 'Dermatitis, Contact', 'Dermatitis, Occupational', 'Dermatomycoses', 'Humans', 'Indonesia', 'Insect Bites and Stings', 'Male', 'Patch Tests', 'Wood'] | 138,502 | [['M01.060.116'], ['C17.800.174.255', 'C17.800.815.255'], ['C17.800.174.255.700', 'C17.800.815.255.700', 'C24.270'], ['C01.150.703.302', 'C01.800.200', 'C17.800.838.208'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.145.380', 'Z01.639.580'], ['C25.723.127.071', 'C26.176.143'], ['E01.370.225.812.871.610',... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 |
Treatment of scleroma with ceforanide. | Three patients with rhinoscleroma who presented with nasal and pharyngeal symptoms are described. Treatment with ceforanide, a new second-generation cephalosporin with high intrinsic activity against Klebsiella, and possessing a long half-life, was used as outpatient treatment. A total of 120 g of ceforanide was admini... | ['Adult', 'Cefamandole', 'Female', 'Humans', 'Injections, Intramuscular', 'Male', 'Rhinoscleroma'] | 3,814,386 | [['M01.060.116'], ['D02.065.589.099.249.150', 'D02.886.665.074.150', 'D03.633.100.300.249.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.460'], ['C01.150.252.400.310.503.500', 'C01.150.252.819.705', 'C01.748.702', 'C01.800.720.705', 'C08.460.850', 'C08.730.702', 'C09.603.850', 'C17.800.838.76... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
ppc, the gene for phosphoenolpyruvate carboxylase from an extremely thermophilic bacterium, Rhodothermus obamensis: cloning, sequencing and overexpression in Escherichia coli. | The ppc gene, which encodes phosphoenolpyruvate carboxylase (PEPC) of an extremely thermophilic bacterium, Rhodothermus obamensis, was directly sequenced by the thermal asymmetric interlaced (TAIL) PCR method. An ORF for a 937 amino acid polypeptide was found in the gene. The ppc gene had a high G+C content (66.2 mol%)... | ['Amino Acid Sequence', 'Amino Acid Substitution', 'Amino Acids', 'Bacteroidetes', 'Blotting, Southern', 'Cloning, Molecular', 'DNA, Bacterial', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Genes, Bacterial', 'Hot Temperature', 'Molecular Sequence Data', 'Phosphoenolpyruvate Carboxylase', 'Phylogeny', 'R... | 9,611,816 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['D12.125'], ['B03.440.080'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['E05.393.220'], ['D13.444.308.212'], ['E05.196.401.402', 'E05.301.300.319'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.02... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Harnessing and controlling the information deluge. | A number of information management tools are available to assist the general practitioner to cope more readily with the deluge of information presented to them. These tools can also enable the practitioner to seek out relevant pieces of information in a timely fashion to assist with patient care. | ['Humans', 'Medical Informatics', 'Medical Informatics Applications', 'Medical Informatics Computing'] | 9,009,013 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500'], ['L01.313.500.750'], ['L01.313.500.875']] | ['Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.