Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Usefulness of combined gastric and esophageal pH monitoring in detecting gastroesophageal alkaline and mixed reflux. | 96 patients with 'typical' symptoms of gastroesophageal reflux were studied by means of combined gastric and esophageal pH monitoring. The aim was to assess the incidence of 'alkaline' and 'mixed' gastroesophageal reflux episodes as well as 'acid' reflux and their reciprocal relationship with esophagitis. 'Alkaline' ga... | ['Esophagitis, Peptic', 'Esophagus', 'Female', 'Gastric Acidity Determination', 'Gastroesophageal Reflux', 'Humans', 'Hydrogen-Ion Concentration', 'Male', 'Middle Aged'] | 6,519,131 | [['C06.405.117.620.420', 'C06.405.205.663.420', 'C06.405.469.275.800.523', 'C06.405.748.586.524'], ['A03.556.875.500'], ['E01.370.225.124.300', 'E01.370.372.300', 'E05.200.124.300'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['M01.060.116.630']] | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Portrayals of treatment decision-making on popular breast and prostate cancer web sites. | The objective of this study was to describe the messages about treatment decision-making on popular cancer web sites, with particular reference to gender differences. The two most popular UK based web sites for breast and prostate cancer were chosen. Qualitative and quantitative comparative content analysis of the two ... | ['Attitude to Health', 'Breast Neoplasms', 'Decision Making', 'Family', 'Female', 'Humans', 'Internet', 'Male', 'Motivation', 'Prostatic Neoplasms', 'Sex Factors'] | 15,842,467 | [['F01.100.150', 'N05.300.150'], ['C04.588.180', 'C17.800.090.500'], ['F02.463.785.373'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['F01.658', 'F01.752.543.500.750'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Effect of ammonia via prepyriform cortex on regulation of food intake in the rat. | Studies were made on whether ammonia, which is an obligatory intermediate of amino acid metabolism, depresses the food intake of rats fed a low-casein (basal) diet containing imbalanced amino acid mixtures (imbalanced diets). Bilateral lesions in the prepyriform cortex caused normalization of food intake of rats fed am... | ['Amino Acids', 'Ammonium Chloride', 'Animals', 'Appetite Regulation', 'Caseins', 'Diet', 'Eating', 'Keto Acids', 'Limbic System', 'Male', 'Neural Pathways', 'Rats', 'Sodium Chloride'] | 984,211 | [['D12.125'], ['D01.210.450.150.050', 'D01.625.062.249'], ['B01.050'], ['G07.203.650.170', 'G07.203.650.390.070.290', 'G10.261.390.070.290'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['G07.203.650.240'], ['G07.203.650.283', 'G10.261.330'], ['D02.241.755'], ['A08.186.211.180'], ['A08.612'], ['B01.050.150.900.649.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of roxatidine acetate (HOE-760) on 24-hour intragastric acidity in healthy volunteers: comparison with ranitidine and placebo. | In a series of double-blind randomized studies in normal volunteers using continuous intragastric pH monitoring, the effects of different dosage regimens of roxatidine, a new H2-receptor antagonist, were compared with placebo and ranitidine. Roxatidine acetate, 75 mg twice daily, decreased median 24 h gastric acidity f... | ['Adolescent', 'Adult', 'Double-Blind Method', 'Gastric Acid', 'Histamine H2 Antagonists', 'Humans', 'Middle Aged', 'Piperidines', 'Ranitidine', 'Reference Values'] | 2,908,751 | [['M01.060.057'], ['M01.060.116'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['A12.200.307.603'], ['D27.505.519.625.375.425.425', 'D27.505.696.577.375.425.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D03.383.621'], ['D03.383.312.750'], ['E05.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tacrolimus- and Nerve Growth Factor-Treated Allografts for Neural Tissue Regeneration. | Treatment of injured peripheral nerves, especially long-distance nerve defects, remains a significant challenge in regenerative medicine due to complex biological conditions and a lack of biomaterials for effective nerve reconstruction. Without proper treatment, nerve injury leads to motor and sensory dysfunction. Here... | ['Allografts', 'Animals', 'Immunosuppressive Agents', 'Nerve Growth Factor', 'Nerve Regeneration', 'PC12 Cells', 'Rats', 'Rats, Wistar', 'Sciatic Neuropathy', 'Tacrolimus'] | 30,525,428 | [['A01.941.500'], ['B01.050'], ['D27.505.696.477.656'], ['D12.644.276.860.437', 'D12.776.467.860.437', 'D12.776.631.600.437', 'D23.529.850.437'], ['G11.561.585', 'G16.762.611'], ['A11.251.210.190.750', 'A11.251.860.180.750', 'A11.299.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease. | Mounting evidence underlines the role of inducible nitric oxide synthase (iNOS) in hepatocellular carcinoma (HCC) development, but its functional interactions with pathways involved in HCC progression remain uninvestigated. Here, we analyzed in preneoplastic and neoplastic livers from Fisher 344 and Brown Norway rats, ... | ['Animals', 'Carcinoma, Hepatocellular', 'Cell Line, Tumor', 'Genetic Predisposition to Disease', 'Humans', 'Incidence', 'Liver Neoplasms', 'Male', 'Mice', 'Mice, Transgenic', 'Nitric Oxide Synthase Type II', 'Prognosis', 'Rats', 'Rats, Inbred BN', 'Rats, Inbred F344', 'Signal Transduction'] | 18,579,559 | [['B01.050'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A11.251.210.190', 'A11.251.860.180'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Detection of changes in the mouse circadian rhythm induced by stress. | Mice were subjected to three types of acute stress (cold, forced swimming and tail hanging) in order to investigate the effects of stress on the motor activity circadian rhythm. This rhythm was studied using the cosinor method and spectral analysis. A statistically significant decrease in the amplitude and the power co... | ['Animals', 'Circadian Rhythm', 'Male', 'Mice', 'Motor Activity', 'Random Allocation', 'Stress, Psychological'] | 3,231,879 | [['B01.050'], ['G07.180.562.190'], ['B01.050.150.900.649.313.992.635.505.500'], ['F01.145.632', 'G11.427.410.698'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['F01.145.126.990', 'F02.830.900']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of atropine and glycopyrrolate on esophageal, gastric, and tracheal pH in anesthetized dogs. | Atropine, glycopyrrolate, or saline solution was administered before anesthesia in a blinded, controlled study of 40 dogs scheduled to undergo surgery. Effects of treatment on esophageal, gastric, and tracheal pH were measured with an intraluminal pH meter. Preanesthetic administration of atropine and glycopyrrolate ha... | ['Anesthesia', 'Animals', 'Atropine', 'Dog Diseases', 'Dogs', 'Esophagus', 'Female', 'Gastric Mucosa', 'Gastroesophageal Reflux', 'Glycopyrrolate', 'Heart Rate', 'Hydrogen-Ion Concentration', 'Male', 'Premedication', 'Pyrrolidines', 'Randomized Controlled Trials as Topic', 'Respiration', 'Stomach', 'Trachea'] | 2,405,583 | [['E03.155'], ['B01.050'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['A03.556.875.500'], ['A03.556.875.875.440', 'A10.615.550.291'], ['C06.405.117.119.500.484'], ['D0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Small bowel necrosis related to enteral nutrition after duodenal surgery. | Nutritional support is the key to the successful recovery of any patient. Small bowel necrosis is described in patients being fed with enteral nutrition after surgery. Five patients with small bowel necrosis after surgery will be discussed and an etiology proposed. A retrospective review of patient data was performed. ... | ['Abdominal Injuries', 'Adult', 'Aged', 'Biopsy, Needle', 'Enteral Nutrition', 'Female', 'Follow-Up Studies', 'Humans', 'Immunohistochemistry', 'Intestinal Diseases', 'Intestine, Small', 'Laparotomy', 'Male', 'Middle Aged', 'Necrosis', 'Pancreatic Neoplasms', 'Pancreaticoduodenectomy', 'Reoperation', 'Retrospective Stu... | 16,447,466 | [['C26.017'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['E02.421.360', 'E02.642.500.360'], ['E05.318.372.500.750.249', 'N05.715.360.330.5... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[Medical-surgical management of heart disease at birth: what approach for what heart disease?]. | The surgical repair of congenital heart defects is governed by three rules: 1) the repair must be as physiological as possible; 2) the cumulated perioperative risk must be reasonable; and 3) the repair must allow normal quality and expectation of life. Surgical management of congenital heart defects at birth also depen... | ['Cardiovascular Surgical Procedures', 'Decision Making', 'Heart Defects, Congenital', 'Hemodynamics', 'Humans', 'Infant, Newborn', 'Prognosis', 'Quality of Life', 'Ventricular Function, Left'] | 11,683,108 | [['E04.100'], ['F02.463.785.373'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.789'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['G09.330.955.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Innervation of the rat anterior abdominal wall as shown by modified Sihler's stain. | OBJECTIVE: The purpose of this study was to use the modified Sihler's staining technique to demonstrate detailed distribution of the rat anterior abdominal wall nerves and test the value of Sihler's technique in demonstrating such a complex muscle-nerve relationship.MATERIALS AND METHODS: The anterior abdominal walls o... | ['Abdominal Wall', 'Animals', 'Coloring Agents', 'Rats', 'Rats, Wistar', 'Staining and Labeling', 'Tissue Fixation'] | 16,484,834 | [['A01.923.047.050'], ['B01.050'], ['D27.720.233'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.500.620.670', 'E05.200.750.600.670'], ['E01.370.225.500.620.760.720', 'E01.370.225.750.600.760.720', 'E05.200.... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A sensitive dot blot procedure for detecting mRNA in lymphoid cells grown in liquid culture. | A sensitive dot blot procedure for detecting RNA transcripts with radiolabelled cDNA probes in small numbers of cells in suspension culture is described. For a frequent mRNA species such as that for immunoglobulin in an IgM secretor hybridoma, as few as 30 cells can be detected using a C mu probe; for a less frequent m... | ['Animals', 'Cell Line', 'Cells, Cultured', 'DNA', 'Genes', 'Genes, Immunoglobulin', 'Lymphocytes', 'Mice', 'Mice, Inbred Strains', 'Mice, Nude', 'Nucleic Acid Hybridization', 'RNA, Messenger', 'Receptors, Antigen, T-Cell', 'T-Lymphocytes', 'Transcription, Genetic'] | 3,257,996 | [['B01.050'], ['A11.251.210'], ['A11.251'], ['D13.444.308'], ['G05.360.340.024.340'], ['G05.360.340.024.340.335', 'G12.500.299'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.4... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of iodide deficiency in Togo using an optimized potentiometric method for iodide estimation in urine. | A pilot study was carried out in two Togolese localities (Gobe, Moretan) situated in an endemic goiter area. The aim of this work was to collect laboratory and nutritional data to assess and follow up campaigns against iodide deficiency. Ninety-seven urine samples were analysed. We studied the urinary excretion and the... | ['Adult', 'Child', 'Female', 'Humans', 'Iodides', 'Male', 'Potentiometry', 'Sodium Chloride', 'Togo', 'Water Supply'] | 7,802,349 | [['M01.060.116'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.490', 'D01.475.410'], ['E05.196.922.750', 'E05.301.710'], ['D01.210.450.150.875', 'D01.857.650'], ['Z01.058.290.190.800'], ['J01.293.821.500']] | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 |
Abscisic acid metabolic genes of wheat (Triticum aestivum L.): identification and insights into their functionality in seed dormancy and dehydration tolerance. | MAIN CONCLUSION: The three homeologues of wheat NCED2 were identified; the wheat NCED2A and CYP707A1B affect seed ABA level and dormancy but not leaf ABA level and transpirational water loss in Arabidopsis. Biosynthesis and catabolism of abscisic acid (ABA) in plants are primarily regulated by 9-cis-epoxycarotenoid dio... | ['Abscisic Acid', 'Arabidopsis', 'Cloning, Molecular', 'Genes, Plant', 'Germination', 'Phylogeny', 'Plant Dormancy', 'Plant Leaves', 'Plant Transpiration', 'Plants, Genetically Modified', 'Sequence Analysis, Protein', 'Triticum', 'Water'] | 27,091,738 | [['D02.241.223.268.034', 'D02.455.326.271.665.202.061', 'D02.455.426.392.368.367.379.249.024', 'D02.455.849.131.061', 'D02.455.849.765.521.500'], ['B01.650.940.800.575.912.250.157.100'], ['E05.393.220'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G07.345.625.249', 'G15.357'], ['G05.697', 'G16.075.605', 'L01.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Role of bradykinin and tachykinins in the potentiation by enalapril of coughing induced by citric acid in pigs. | Angiotensin-converting enzyme (ACE) inhibitors are among the first-choice drugs for treating hypertension and congestive heart disease. It has been reported, however, that these drugs could induce chronic cough and airway hyperresponsiveness. The aim of this work was to assess in pigs the effects of bradykinin and tach... | ['Adrenergic beta-Antagonists', 'Angiotensin-Converting Enzyme Inhibitors', 'Animals', 'Antitussive Agents', 'Bradykinin', 'Citric Acid', 'Cough', 'Dose-Response Relationship, Drug', 'Drug Synergism', 'Enalapril', 'Female', 'Male', 'Receptors, Tachykinin', 'Swine', 'Tachykinins'] | 11,468,010 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['D27.505.519.389.745.085'], ['B01.050'], ['D27.505.954.427.153', 'D27.505.954.796.090'], ['D12.644.276.812.169', 'D12.644.400.090', 'D12.644.456.193', 'D12.776.467.812.169', 'D12.776.631.650.090', 'D23.469.050.375.110', 'D23.529.812.169'], ['D02.241.081.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rice Grain Quality Benchmarking Through Profiling of Volatiles and Metabolites in Grains Using Gas Chromatography Mass Spectrometry. | Gas chromatograph coupled with mass spectrometer is widely used to profile volatiles and metabolites from the homogenized rice flour obtained from mature grains. Rice grains consist of central endosperm which stores majorly starch and, in addition, accumulate various storage proteins as storage reserves. The outer nutr... | ['Data Interpretation, Statistical', 'Edible Grain', 'Gas Chromatography-Mass Spectrometry', 'Metabolome', 'Metabolomics', 'Oryza', 'Volatile Organic Compounds'] | 30,397,807 | [['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['A18.024.500.750.500', 'B01.650.160.250', 'B01.650.510.250', 'G07.203.300.300.550', 'G07.203.300.775.500', 'J02.500.300.550', 'J02.500.775.500'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G03.500'], ['H01.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Flaws and pitfalls in the chemical analysis of feathers: bad news-good news for avian chemoecology and toxicology. | Ecologists have frequently used biochemical assays as proxies for processes or phenomena too difficult to explore by traditional means of investigation. Feathers have been subjected to a number of chemical analyses to study such things as their elemental composition, contaminants, and hormones. The reliance on standard... | ['Animals', 'Birds', 'Environmental Monitoring', 'Environmental Pollutants', 'Feathers'] | 20,945,774 | [['B01.050'], ['B01.050.150.900.248'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D27.888.284'], ['A13.370']] | ['Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Brain-specific receptor-type protein-tyrosine phosphatase RPTP beta is a chondroitin sulfate proteoglycan in vivo. | By using polyclonal antiserum, which recognizes multiple proteoglycan core proteins, we isolated a cDNA species for an unknown chondroitin sulfate proteoglycan in bovine brain. Unexpectedly, DNA sequencing revealed that the cDNA encodes an open reading frame highly homologous to the human receptor-type protein-tyrosine... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Brain', 'Cattle', 'Cerebellum', 'Chondroitin Sulfate Proteoglycans', 'Cloning, Molecular', 'DNA, Complementary', 'Humans', 'Molecular Sequence Data', 'Nerve Tissue Proteins', 'Protein Tyrosine Phosphatases', 'RNA, Messenger', 'Receptor-Like Protein Tyrosine Phosphata... | 8,051,107 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A08.186.211'], ['B01.050.150.900.649.313.500.380.271'], ['A08.186.211.132.810.428.200'], ['D09.698.735.200', 'D12.776.395.650.750'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A 37-Year-Old Man With Pleuritic Chest Pain. | CASE PRESENTATION: A 37-year-old man with poorly controlled type 2 diabetes presented with severe right-sided pleuritic chest pain, respiratory splinting, and cough. Two weeks earlier, he had been evaluated at an urgent care for cough and was prescribed a 5-day course of azithromycin for bronchitis. He then presented t... | ['Adult', 'Antifungal Agents', 'Chest Pain', 'Chest Tubes', 'Coccidioides', 'Coccidioidomycosis', 'Combined Modality Therapy', 'Diagnosis, Differential', 'Humans', 'Lung Diseases, Fungal', 'Male', 'Thoracic Surgery, Video-Assisted'] | 31,279,380 | [['M01.060.116'], ['D27.505.954.122.136'], ['C23.888.592.612.233'], ['E07.858.150'], ['B01.300.381.230'], ['C01.150.703.203'], ['E02.186'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.703.534', 'C01.748.435', 'C08.381.472', 'C08.730.435'], ['E01.370.388.250.840.830', 'E01.370.388.250.950.830... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inductive vs solvation effects in primary alkyl amines: determination of the standard potentials. | The determination of the standard potential of alkyl primary amines is reported for the first time using the nanosecond equilibrium method. The versatility and accuracy of the method demonstrates that it is not only an alternative to the classical and modern electrochemical methods, but also a powerful tool for quantif... | ['Alkanes', 'Amines', 'Electrochemistry', 'Molecular Structure', 'Solvents'] | 17,298,061 | [['D02.455.326.146'], ['D02.092'], ['H01.181.529.307'], ['G02.111.570', 'G02.466'], ['D27.720.844']] | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Results of acetabular wiremesh and autograft in protrusio acetabuli. | Between 1990 and 2005, 25 acetabular reconstructions in 25 patients were performed using autogenous morcellized bone-graft and acetabular wiremesh due to acetabular bone stock loss. The most frequent preoperative diagnosis in our patients were severe hip arthrosis (50%), and rheumatoid arthritis (15%).The mean follow u... | ['Acetabulum', 'Aged', 'Aged, 80 and over', 'Arthritis, Rheumatoid', 'Arthroplasty, Replacement, Hip', 'Bone Transplantation', 'Female', 'Follow-Up Studies', 'Health Status Indicators', 'Hip Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Osteoarthritis, Hip', 'Osteolysis', 'Osteotomy', 'Postoperative Complications', 'P... | 18,645,970 | [['A02.835.232.043.825.108'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['E05.318.372.500.750.249', 'N05.715.360.330.500... | ['Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chronic toxicity of azo and anthracenedione dyes to embryo-larval fathead minnow. | The toxicity of selected azo and anthracenedione dyes was studied using chronic exposures of embryo-larval fathead minnows (Pimephales promelas). Newly fertilized fathead minnow embryos were exposed through the egg stage, past hatching, through the larval stage (until 14 days post-hatch), with dye solutions renewed dai... | ['Animals', 'Anthraquinones', 'Azo Compounds', 'Coloring Agents', 'Cyprinidae', 'Larva', 'Toxicity Tests, Chronic'] | 26,704,269 | [['B01.050'], ['D02.455.426.559.847.117.159', 'D02.806.100', 'D04.615.117.159'], ['D02.172'], ['D27.720.233'], ['B01.050.150.900.493.200.244'], ['B05.500.500', 'G07.345.500.550.500.500'], ['E05.940.800']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Magnetic resonance elastography of the breast: correlation of signal intensity data with viscoelastic properties. | OBJECTIVES: We sought to investigate the potential value of magnetic resonance (MR) elastography to improve the differentiation between benign and malignant tumors.MATERIAL AND METHODS: Measurements of 5 patients with 6 malignant lesions, 11 patients with benign lesions, and 4 patients with no lesions at all were perfo... | ['Adolescent', 'Adult', 'Breast Neoplasms', 'Diagnosis, Differential', 'Elasticity', 'Female', 'Humans', 'Image Enhancement', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Middle Aged', 'Ultrasonography, Mammary'] | 15,973,132 | [['M01.060.057'], ['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['E01.171'], ['G01.374.590'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['L01.224.308'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E01.370.350.850.860', 'E01.370.378.850']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Clinical characteristics and prognosis of vasculitic mononeuropathy multiplex. | The initial appearance and course of 19 patients with mononeuropathy multiplex due to systemic vasculitis were evaluated. Neuropathy first occurred within one year of the onset of systemic vasculitis in all patients and within one year of the onset of rheumatoid arthritis in four of nine patients. Concurrent cutaneous ... | ['Adult', 'Aged', 'Arthritis, Rheumatoid', 'Female', 'Humans', 'Male', 'Middle Aged', 'Peripheral Nervous System Diseases', 'Prognosis', 'Vasculitis'] | 6,326,716 | [['M01.060.116'], ['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.668.829'], ['E01.789'], ['C14.907.940']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Active compression-decompression resuscitation: analysis of transmitral flow and left ventricular volume by transesophageal echocardiography in humans. Cardiopulmonary Resuscitation Working Group. | OBJECTIVES: This study was designed to test the hypothesis that active compression-decompression cardiopulmonary resuscitation increases transmitral flow and end-decompression left ventricular volume over levels achieved with standard manual cardiopulmonary resuscitation.BACKGROUND: Recently, cardiopulmonary resuscitat... | ['Aged', 'Cardiopulmonary Resuscitation', 'Echocardiography, Transesophageal', 'Equipment Design', 'Female', 'Heart Arrest', 'Heart Massage', 'Humans', 'Linear Models', 'Male', 'Middle Aged', 'Mitral Valve', 'Stroke Volume', 'Time Factors'] | 8,227,809 | [['M01.060.116.100'], ['E02.365.647.110'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['E05.320'], ['C14.280.383'], ['E02.365.647.375', 'E04.100.376.458', 'E04.928.220.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A unique cellular myosin II exhibiting differential expression in the cerebral cortex. | Clones possessing inserts of brain myosin II have been obtained by screening a rat brain cDNA expression library with a polyclonal antibody, raised against myosin II from the mouse neuroblastoma cell line, Neuro-2A. A partial sequence comprising the 3' coding and non-coding regions of the myosin message has been determ... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Brain', 'Cell Line', 'Cerebral Cortex', 'DNA Probes', 'Gene Library', 'Molecular Sequence Data', 'Myosins', 'Neuroblastoma', 'Protein Conformation', 'Rats', 'Restriction Mapping', 'Sequence Homology, Nucleic Acid'] | 1,998,509 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A08.186.211'], ['A11.251.210'], ['A08.186.211.200.885.287.500'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['G05.360.325'], ['L01.453.245.667'], ['D05.750.078.730.475',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prenatal findings in a monozygotic twin pregnancy with Costello syndrome. | This report describes the prenatal findings in monozygotic twins with Costello syndrome. At 16 weeks one twin had 9 mm of nuchal oedema: coarctation of the aorta was diagnosed after birth. At 22(5/7) weeks relative macrocephaly, mild pyelectasia and moderate polyhydramnios were noted in both twins. In the following 4 w... | ['Abnormalities, Multiple', 'Adult', 'Diseases in Twins', 'Fatal Outcome', 'Female', 'Fetal Diseases', 'Humans', 'Polyhydramnios', 'Pregnancy', 'Prenatal Diagnosis', 'Syndrome', 'Twins, Monozygotic'] | 12,001,198 | [['C16.131.077'], ['M01.060.116'], ['C23.550.291.750'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C13.703.277', 'C16.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.703.610'], ['G08.686.784.769'], ['E01.370.378.630'], ['C23.550.288.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A reappraisal of Fe(III) adsorption by melanin. | The adsorptive capacity of melanin for Fe(III) was investigated. Iron is involved in promoting the formation of reactive oxygen species which has consequently been associated with Parkinson's disease. Neuromelanin has been suggested to act as an iron scavenger and, therefore, determining the capacity of melanin to adso... | ['Adsorption', 'Animals', 'Chelating Agents', 'Dose-Response Relationship, Drug', 'Ferric Compounds', 'Humans', 'Hydrogen-Ion Concentration', 'Iron', 'Melanins', 'Reactive Oxygen Species', 'Time Factors'] | 24,845,878 | [['G01.030', 'G02.020'], ['B01.050'], ['D27.505.519.914.500', 'D27.720.832.500'], ['G07.690.773.875', 'G07.690.936.500'], ['D01.490.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D12.125.072.050.875.379', 'D23.767.620'], ['D01.339.431', ... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pharmacological characterization of ionic currents that regulate the pacemaker rhythm in a weakly electric fish. | Electric organ discharge (EOD) frequency in the brown ghost knifefish (Apteronotus leptorhynchus) is sexually dimorphic, steroid-regulated, and determined by the discharge rates of neurons in the medullary pacemaker nucleus (Pn). We pharmacologically characterized ionic currents that regulate the firing frequency of Pn... | ['4-Aminopyridine', 'Action Potentials', 'Animals', 'Biological Clocks', 'Cadmium', 'Calcium Channel Blockers', 'Calcium Channels', 'Cells, Cultured', 'Conotoxins', 'Dose-Response Relationship, Drug', 'Electric Fish', 'Electric Organ', 'In Vitro Techniques', 'Neurons', 'Nickel', 'Nifedipine', 'Potassium Channel Blocker... | 10,640,333 | [['D02.092.080.060', 'D03.383.725.050.060'], ['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['G07.180.562.094'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Study of the posterior spiracles of Drosophila as a model to understand the genetic and cellular mechanisms controlling morphogenesis. | We have studied the posterior spiracles of Drosophila as a model to link patterning genes and morphogenesis. A genetic cascade of transcription factors downstream of the Hox gene Abdominal-B subdivides the primordia of the posterior spiracles into two cell populations that develop using two different morphogenetic mech... | ['Animals', 'Body Patterning', 'Cell Nucleus', 'Cell Polarity', 'DNA-Binding Proteins', 'Drosophila', 'Embryo, Nonmammalian', 'Fungal Proteins', 'Gene Expression Regulation, Developmental', 'Genes, Homeobox', 'Genetic Markers', 'Models, Biological', 'Morphogenesis', 'Recombinant Proteins', 'Saccharomyces cerevisiae Pro... | 10,491,268 | [['B01.050'], ['G07.345.500.100'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G04.250'], ['D12.776.260'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['A13.350', 'A16.331'], ['D12.776.354'], ['G05.308.310'], ['G05.360.340.024.340.230.500'], ['D23.101.387', 'G05.695.450'], ['E05.599.395'], ['G07.345.500'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
mRNA expression profiling of laser microbeam microdissected cells from slender embryonic structures. | Microarray hybridization has rapidly evolved as an important tool for genomic studies and studies of gene regulation at the transcriptome level. Expression profiles from homogenous samples such as yeast and mammalian cell cultures are currently extending our understanding of biology, whereas analyses of multicellular o... | ['Animals', 'Embryo, Mammalian', 'Female', 'Gene Expression Profiling', 'Gene Expression Regulation, Developmental', 'Lasers', 'Mice', 'Mice, Inbred C57BL', 'Micromanipulation', 'Oligonucleotide Array Sequence Analysis', 'Pregnancy', 'RNA, Messenger'] | 11,891,179 | [['B01.050'], ['A16.254'], ['E05.393.332'], ['G05.308.310'], ['E07.632.490', 'E07.710.520'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['E05.591'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['G08.686.7... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Myeloid leukemia with high EVI1 expression is sensitive to 5-aza-2'-deoxycytidine by targeting miR-9. | PURPOSE: High expression of ecotropic viral integration site 1 (EVI1) has been associated with a poor prognosis in leukemia patients, but the underlying mechanism remains unclear. Aberrant expression of microRNAs plays critical roles in leukemia development. MiR-9 is a putative potential target of EVI1. We have investi... | ['Antimetabolites, Antineoplastic', 'Apoptosis', 'Biomarkers, Tumor', 'Cell Cycle', 'Cell Proliferation', 'DNA Methylation', 'Decitabine', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Leukemia, Myeloid, Acute', 'MDS1 and EVI1 Complex Locus Protein', 'MicroRNAs', 'Promoter Regions, Genetic', 'Tumor Cells, Cultur... | 31,054,042 | [['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['G04.146.954.035'], ['D23.101.140'], ['G04.144'], ['G04.161.750', 'G07.345.249.410.750'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D02.145.150.500', 'D03.383.742.680.245.217.500', 'D13.570.685.245.217.500', 'D13.570.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Potentiation of 1-beta-D-arabinofuranosylcytosine cytotoxicity to HL-60 cells by 1,25-dihydroxyvitamin D3 correlates with reduced rate of maturation of DNA replication intermediates. | S-phase-active cytotoxic drugs selectively damage leukemic cells, but the mechanisms of this action are not clear. We have investigated the previously reported potentiation of toxicity of 1-beta-D-arabinofuranosylcytosine (ara-C) to HL-60 cells by the differentiation-inducing steroid, 1,25-dihydroxyvitamin D3 [1,25(OH)... | ['Arabinofuranosylcytosine Triphosphate', 'Calcitriol', 'Cell Differentiation', 'Cell Survival', 'Cytarabine', 'DNA Damage', 'DNA Replication', 'Drug Administration Schedule', 'Drug Synergism', 'Humans', 'Structure-Activity Relationship', 'Tumor Cells, Cultured'] | 2,054,784 | [['D03.383.742.686.246.050', 'D13.695.065.200', 'D13.695.740.246.050'], ['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.938.146.478.387.300'], ['G04.152'], ['G04.346'], ['D03.383.742.680.245.453', 'D13.570.065.300', 'D13.570.685.245.453'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Medial temporal theta/alpha power enhancement precedes successful memory encoding: evidence based on intracranial EEG. | Not only poststimulus, but also prestimulus neural activity has been shown to be predictive for later successful memory encoding. However, it is still not clear which medial temporal lobe processes precede effective memory formation. Here, our aim was to investigate whether such prestimulus markers for successful memor... | ['Adolescent', 'Adult', 'Alpha Rhythm', 'Brain Mapping', 'Child', 'Child, Preschool', 'Electroencephalography', 'Epilepsy, Temporal Lobe', 'Female', 'Hippocampus', 'Humans', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Photic Stimulation', 'Reaction Time', 'Recognition, Psychology', 'Statistics, Nonparametric', ... | 21,471,374 | [['M01.060.057'], ['M01.060.116'], ['E01.370.376.300.150.374', 'E01.370.405.245.287.374', 'G07.265.087.500', 'G11.561.127.500'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.360.290', 'C10.228.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Design and evaluation of prostaglandin E1 (PGE1) intraurethral liquid formulation employing self-microemulsifying drug delivery system (SMEDDS) for erectile dysfunction treatment. | Liquid intraurethral prostaglandin E1 (PGE1) delivery system was developed using self-microemulsifying drug delivery system (SMEDDS). For this, pseudo-ternary phase diagrams were constructed and characterized. The viscosity of optimized formulation was increased gradually upon the addition of water and it was decreased... | ['Alprostadil', 'Animals', 'Cats', 'Chemistry, Pharmaceutical', 'Drug Delivery Systems', 'Emulsions', 'Erectile Dysfunction', 'Excipients', 'Injections', 'Irritants', 'Male', 'Particle Size', 'Penile Erection', 'Penis', 'Rabbits', 'Solvents', 'Urethra', 'Vasodilator Agents', 'Viscosity'] | 18,379,060 | [['D10.251.355.255.550.250.100', 'D10.251.355.325.050', 'D23.469.050.175.725.250.100'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['H01.158.703.007', 'H01.181.466'], ['E02.319.300'], ['D20.280.260', 'D26.255.165.260'], ['C12.294.644.486', 'F03.835.400'], ['D26.650.700.419', 'D27.720.744.770.419'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Cochlear ablation alters acoustically induced c-fos mRNA expression in the adult rat auditory brainstem. | Expression of c-fos mRNA was studied in the adult rat brain following cochlear ablations by using in situ hybridization. In normal animals, expression was produced by acoustic stimulation and was found to be tonotopically distributed in many auditory nuclei. Following unilateral cochlear ablation, acoustically driven e... | ['Acoustic Stimulation', 'Animals', 'Auditory Pathways', 'Brain Stem', 'Cochlea', 'Male', 'Proto-Oncogene Proteins c-fos', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Tissue Distribution'] | 9,934,999 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['B01.050'], ['A08.612.220.110'], ['A08.186.211.132'], ['A09.246.300.246'], ['D12.776.260.108.765', 'D12.776.624.664.700.179', 'D12.776.660.760', 'D12.776.930.127.765'], ['D13.444.735.544'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Investigating the Lived Experience of Recovery in People Who Hear Voices. | Although there is evidence of both clinical and personal recovery from distressing voices, the process of recovery over time is unclear. Narrative inquiry was used to investigate 11 voice-hearers' lived experience of recovery. After a period of despair/exhaustion, two recovery typologies emerged: (a) turning toward/emp... | ['Hallucinations', 'Humans', 'Narration', 'Power, Psychological', 'Voice'] | 25,896,792 | [['C10.597.606.762.300', 'C23.888.592.604.764.300', 'F01.700.750.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.502', 'F01.145.209.459', 'L01.399.250.660', 'N05.715.360.300.480', 'N06.850.520.308.502'], ['F01.658.780'], ['G09.772.925']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Relative efects of nutritients on carcenogenesis. | In this study, we analyzed nutritional behavior of patients with lung cancer, especially vegetable and fruit intake, and smoking preceding the discase onset. Study was performed during 2002. Among study subjects there were more patients of age 25-64 (64%) than those older than 65 (36%). Lung cancer patients had less ve... | ['Adult', 'Aged', 'Diet', 'Humans', 'Lung Neoplasms', 'Middle Aged', 'Smoking'] | 15,648,231 | [['M01.060.116'], ['M01.060.116.100'], ['G07.203.650.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['F01.145.805']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Use of staphylococcal enterotoxin A-induced lymphoproliferation and interleukin 2 production as indicators of immunotoxicity. | Suppression of mitogen-induced splenocyte lymphoproliferation and interleukin 2 (IL-2) production can be used as indicators of immunotoxicity. Staphylococcal enterotoxin A (SEA) is both a potent mitogen and the most potent in vitro inducer of IL-2 production that has been described. An in vitro system was used to measu... | ['Animals', 'Benzene', 'Cyclosporine', 'Enterotoxins', 'Female', 'Interleukin-2', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred C57BL', 'Spleen', 'Toxicology'] | 8,168,430 | [['B01.050'], ['D02.455.426.559.389.023'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['D23.946.330'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.480.372', 'D23.529.374.465.155', 'D23.529.374.480.372'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of two different adenoidectomy techniques with special emphasize on postoperative nasal mucociliary clearance rates: coblation technique vs. cold curettage. | OBJECTIVE: To compare the cold curettage and coblation techniques for pediatric adenoidectomy by means of intraoperative blood loss, operation time, and pre- and postoperative nasal mucociliary clearance rates.METHODS: The study included 60 consecutive patients undergoing adenoidectomy operation upon the diagnosis of a... | ['Adenoidectomy', 'Adenoids', 'Child', 'Child, Preschool', 'Curettage', 'Female', 'Humans', 'Hypertrophy', 'Male', 'Mucociliary Clearance', 'Treatment Outcome'] | 23,266,160 | [['E04.580.068'], ['A04.623.557.500', 'A10.549.100', 'A14.724.557.500', 'A15.382.520.604.100'], ['M01.060.406'], ['M01.060.406.448'], ['E04.157'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.775'], ['E01.370.386.520', 'G09.772.555'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Neonatal caffeine exposure and seizure susceptibility in adult rats. | Early developmental exposure to caffeine in rats results in changes in brain excitability that persist to adulthood. The mechanism of these alterations is unknown. To identify potential neurotransmitter systems involved, we exposed neonatal rats to caffeine and determined seizure thresholds for chemoconvulsants active ... | ['Animals', 'Animals, Newborn', 'Bicuculline', 'Brain', 'Caffeine', 'Female', 'Kainic Acid', 'Male', 'Pentylenetetrazole', 'Picrotoxin', 'Rats', 'Receptors, Purinergic P1', 'Seizures', 'Sex Factors', 'Strychnine'] | 7,635,092 | [['B01.050'], ['B01.050.050.282'], ['D03.132.098.077', 'D03.633.100.531.085.077'], ['A08.186.211'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D03.383.773.400'], ['D03.383.066.600'], ['D02.455.426.392.368.367.800', 'D02.540.552'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.543.750.695.700.700', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of lipid physical state of palm derivatives on â-carotene bleaching. | This research was addressed to study the effect of lipid physical state on bleaching kinetics of â-carotene. To this aim, â-carotene was added to palm oil and palm stearin and the samples were stored at increasing temperatures allowing different degree of crystallization. Phase transition properties of palm derivatives... | ['Calorimetry, Differential Scanning', 'Chemical Phenomena', 'Crystallization', 'Food Handling', 'Kinetics', 'Palm Oil', 'Phase Transition', 'Plant Oils', 'Temperature', 'Triglycerides', 'X-Ray Diffraction', 'beta Carotene'] | 23,488,868 | [['E05.196.131.310', 'E05.196.370.310'], ['G02'], ['E05.196.300', 'G02.171'], ['J01.576.423.200'], ['G01.374.661', 'G02.111.490'], ['D10.627.700.798', 'D20.215.784.750.728'], ['G01.645', 'G02.734'], ['D10.627.700', 'D20.215.784.750'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Genetic variation in the PTH pathway and bone phenotypes in elderly women: evaluation of PTH, PTHLH, PTHR1 and PTHR2 genes. | INTRODUCTION: Parathyroid hormone (PTH) is a key regulator of calcium metabolism. Parathyroid hormone-like hormone (PTHrP) contributes to skeletal development through regulation of chondrocyte proliferation and differentiation during early bone growth. Both PTH and PTHrP act through the same receptor (PTHR1). A second ... | ['Aged', 'Bone Density', 'Bone and Bones', 'Female', 'Fractures, Bone', 'Genotype', 'Humans', 'Mutation', 'Osteoporosis', 'Parathyroid Hormone', 'Parathyroid Hormone-Related Protein', 'Phenotype', 'Polymorphism, Genetic', 'Receptor, Parathyroid Hormone, Type 1', 'Receptor, Parathyroid Hormone, Type 2', 'Risk Factors', ... | 18,280,230 | [['M01.060.116.100'], ['G11.427.100'], ['A02.835.232', 'A10.165.265'], ['C26.404'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590'], ['C05.116.198.579', 'C18.452.104.579'], ['D06.472.699.590', 'D12.644.548.587'], ['D06.472.699.591', 'D12.644.276.908', 'D12.644.548.588', 'D12.776.467.890', ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Diarrhea-associated pathogens, lactobacilli and cellulolytic bacteria in equine feces: responses to antibiotic challenge. | Antibiotics are important to equine medicine, but antibiotic-associated diarrhea (AAD) can lead to poor performance and even mortality. AAD is attributed to disruption of the hindgut microbiota, which permits proliferation of pathogenic microbes. The goal of this study was to evaluate the effects of common antibiotics ... | ['Animals', 'Anti-Bacterial Agents', 'Bacteria', 'Bacterial Infections', 'Cellulose', 'Diarrhea', 'Feces', 'Female', 'Horse Diseases', 'Horses', 'Lactobacillus', 'Male', 'Microbial Sensitivity Tests'] | 23,769,300 | [['B01.050'], ['D27.505.954.122.085'], ['B03'], ['C01.150.252'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['C23.888.821.214'], ['A12.459'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.550.450.475']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effects of intravenous lidocaine on isoflurane concentration, physiological parameters, metabolic parameters and stress-related hormones in horses undergoing surgery. | Physiological parameters, metabolic parameters and stress-related hormones are evaluated in horses anaesthetized with isoflurane in oxygen combined with lidocaine intravenously. Two groups of horses anaesthetized with isoflurane (six horses in each group) were studied: a lidocaine group (IL), which received intravenous... | ['Anesthesia', 'Anesthetics', 'Anesthetics, Combined', 'Anesthetics, Inhalation', 'Anesthetics, Intravenous', 'Anesthetics, Local', 'Animals', 'Drug Interactions', 'Enzymes', 'Female', 'Hemodynamics', 'Horses', 'Hydrocortisone', 'Infusions, Intravenous', 'Insulin', 'Isoflurane', 'Ketamine', 'Lidocaine', 'Male', 'Midazo... | 12,948,155 | [['E03.155'], ['D27.505.696.277.100', 'D27.505.954.427.210.100'], ['D27.505.696.277.100.017', 'D27.505.954.427.210.100.017'], ['D27.505.696.277.100.035.060', 'D27.505.954.427.210.100.035.060'], ['D27.505.696.277.100.035.075', 'D27.505.954.427.210.100.035.075'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Interleukin-1beta gene polymorphism associated with radiographic signs of osteoarthritis of the knee. | BACKGROUND: Osteoarthritis is recognized as a noninflammatory, progressive condition, the principal cause of which is regressive changes associated with aging and which pursues a chronic course. Recently, the involvement of genetic factors has been widely reported. The purpose of this study was to identify polymorphism... | ['Adult', 'Aged', 'Aged, 80 and over', 'Case-Control Studies', 'Female', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Interleukin-1beta', 'Male', 'Middle Aged', 'Osteoarthritis, Knee', 'Polymorphism, Single Nucleotide', 'Radiography'] | 18,392,912 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Furfural production from xylose using sulfonic ion-exchange resins (Amberlyst) and simultaneous stripping with nitrogen. | The aim of this work deals with the development of new approaches to the production of furfural from xylose. It combines relatively cheap heterogeneous catalysts (Amberlyst 70) with simultaneous furfural stripping using nitrogen under semi-batch conditions. Nitrogen, compared to steam, does not dilute the vapor phase s... | ['Catalysis', 'Furaldehyde', 'Kinetics', 'Models, Chemical', 'Nitrogen', 'Phase Transition', 'Xylose'] | 21,624,830 | [['G02.130'], ['D02.047.466', 'D03.383.312.355'], ['G01.374.661', 'G02.111.490'], ['E05.599.495'], ['D01.268.604', 'D01.362.625'], ['G01.645', 'G02.734'], ['D09.947.875.627.867']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Abl tyrosine kinase regulates a Rac/JNK and a Rac/Nox pathway for DNA synthesis and Myc expression induced by growth factors. | The cytoplasmic tyrosine kinase Abl is a Src substrate required for platelet-derived growth factor (PDGF) receptor signaling leading to Myc expression and DNA synthesis. Abl targets are, however, ill defined. Here we report that the small GTPase Rac is an important effector of its mitogenic function. PDGF-induced Rac a... | ['Animals', 'DNA', 'DNA Replication', 'Enzyme Induction', 'Fibroblasts', 'G1 Phase', 'Gene Expression Regulation, Enzymologic', 'Genes, cdc', 'JNK Mitogen-Activated Protein Kinases', 'MAP Kinase Kinase 4', 'Mice', 'Mitosis', 'Mutation', 'NADH, NADPH Oxidoreductases', 'NADPH Oxidase 1', 'NIH 3T3 Cells', 'Platelet-Derive... | 16,076,903 | [['B01.050'], ['D13.444.308'], ['G02.111.225', 'G05.226'], ['G05.308.320.200'], ['A11.329.228'], ['G04.144.500.320'], ['G05.308.320'], ['G05.360.340.024.340.220'], ['D08.811.913.696.620.682.700.567.374', 'D12.644.360.450.340', 'D12.776.476.450.340'], ['D08.811.913.696.620.682.700.565.400', 'D08.811.913.696.620.682.725.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of uremic serum on 1,25-dihydroxyvitamin D3-induced differentiation of a human promyelocytic leukemia cell line, HL-60. | The mechanism by which resistance to 1,25 dihydroxyvitamin D3 (1,25-(OH)2D3) occurs in patients with chronic renal failure was studied. This agent induces differentiation and 1,25-(OH)2D3-24-hydroxylase activity in the mitochondria of the human promyelocytic leukemia cell line, HL-60, via a steroid-hormone receptor mec... | ['Adult', 'Aged', 'Calcitriol', 'Cell Differentiation', 'Cyclic AMP', 'Female', 'Humans', 'Leukemia, Promyelocytic, Acute', 'Male', 'Receptors, Calcitriol', 'Receptors, Steroid', 'Tumor Cells, Cultured', 'Uremia'] | 1,668,175 | [['M01.060.116'], ['M01.060.116.100'], ['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.938.146.478.387.300'], ['G04.152'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Acceptability and accuracy of a non-endoscopic screening test for Barrett's oesophagus in primary care: cohort study. | OBJECTIVES: To determine the accuracy and acceptability to patients of non-endoscopic screening for Barrett's oesophagus, using an ingestible oesophageal sampling device (Cytosponge) coupled with immunocytochemisty for trefoil factor 3.DESIGN: Prospective cohort study.SETTING: 12 UK general practices, with gastroscopie... | ['Aged', 'Anxiety', 'Barrett Esophagus', 'Equipment Design', 'Female', 'Gastroscopy', 'Gelatin Sponge, Absorbable', 'Humans', 'Immunohistochemistry', 'Male', 'Mass Screening', 'Middle Aged', 'Patient Satisfaction', 'Peptides', 'Prospective Studies', 'Sensitivity and Specificity', 'Trefoil Factor-3'] | 20,833,740 | [['M01.060.116.100'], ['F01.470.132'], ['C04.834.154', 'C06.405.117.102'], ['E05.320'], ['E01.370.372.250.250.325', 'E01.370.388.250.250.250.320', 'E04.210.240.250.320', 'E04.502.250.250.250.320'], ['E07.858.740.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Studies on digestion and absorption in the intestines of growing pigs. 2. Measurements of the flow of dry matter, ash and water. | 1. Digesta were collected from twenty-three pigs, initially of 30 kg live weight, and fitted with single Ash re-entrant cannulas in either the duodenum, jejunum or ileum. A further twenty-four pigs were used in a conventional digestibility trial. 2. The diets contained: barley, fine wheat offal, white fish meal, minera... | ['Animal Feed', 'Animals', 'Digestion', 'Gastrointestinal Motility', 'Intestinal Absorption', 'Male', 'Swine', 'Water'] | 638,121 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['G07.203.650.250', 'G10.261.190'], ['G10.261.360'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.374.500', 'G10.261.353.500'], ['B01.050.150.900.649.313.500.880'], ['D01.045.250.875', 'D01.248.497.158.459.650', ... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Therapeutic farriery: one veterinarian's perspective. | Therapeutic shoeing is best directed at a specific diagnosis, but in the absence of a specific diagnosis, it is frequently directed at a symptom. There are only so many ways to modify the function of the foot with trimming and shoeing. The design of a horse shoe may often be modified to improve one aspect of foot funct... | ['Animal Husbandry', 'Animals', 'Biomechanical Phenomena', 'Energy Transfer', 'Equipment Design', 'Foot Diseases', 'Gait', 'Hoof and Claw', 'Horse Diseases', 'Horses', 'Lameness, Animal', 'Movement', 'Shoes', 'Stress, Mechanical', 'Traction', 'Weight-Bearing'] | 22,981,193 | [['J01.040.090'], ['B01.050'], ['G01.154.090', 'G01.374.089'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['E05.320'], ['C05.360', 'C17.800.321'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['A13.491'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['C22.510'], ['G07.568', 'G11.427.410'], ['J01.637.215.800... | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[The effect of damage to the locus coeruleus or the raphe nuclei on circadian rhythms in rats in open-field testing]. | The electrolytic lesions of raphe or locus coeruleus (I = 1-1.5 mA, 20 sec, with a change in polarity) produce a destabilization in the circadian rhythms of the active searching behaviour (tested in the "open field") in rats kept under conditions of natural illumination in the period of the winter or summer solstice. T... | ['Animals', 'Circadian Rhythm', 'Exploratory Behavior', 'Locus Coeruleus', 'Male', 'Photoperiod', 'Raphe Nuclei', 'Rats', 'Rats, Wistar', 'Receptors, Adrenergic', 'Receptors, Serotonin', 'Seasons', 'Time Factors'] | 9,273,797 | [['B01.050'], ['G07.180.562.190'], ['F01.145.387', 'F01.658.370'], ['A08.186.211.132.659.473', 'A08.186.211.132.810.428.600.650.437'], ['G01.910.675'], ['A08.186.211.132.659.413.875.618', 'A08.186.211.132.810.428.600.650.562', 'A08.186.211.132.810.591.500.662'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.15... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Urinary incontinence among Turkish women: an outpatient study of prevalence, risk factors, and quality of life. | PURPOSE: The aim of this study was to determine the prevalence and potential risk factors associated with urinary incontinence (UI) in women and to assess its impact on quality of life (QOL).DESIGN: We undertook a cross-sectional study based on interviews, using a structured questionnaire.SUBJECTS AND SETTING: Two hund... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Female', 'Humans', 'Middle Aged', 'Outpatient Clinics, Hospital', 'Prevalence', 'Quality of Life', 'Risk Factors', 'Surveys and Questionnaires', 'Turkey', 'Young Adult'] | 22,652,936 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N02.278.035.380', 'N02.278.216.500.968.527', 'N04.452.442.452.422.527'], ['E05.318.308.985.525.750', 'N01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Experimental amebiasis: immunohistochemical study of immune cell populations. | Distribution of immune cell populations was studied in a C3H/HeJ mouse model of intestinal amebiasis from 5 to 60 days post-inoculation with Entamoeba histolytica, using immunoperoxidase techniques. At various time intervals, the ceca from mice were fixed in 10% formalin, dehydrated, embedded and sectioned at 5 microm.... | ['Animals', 'Cecum', 'Disease Models, Animal', 'Dysentery, Amebic', 'Entamoeba histolytica', 'Female', 'Humans', 'Immunity, Cellular', 'Immunity, Mucosal', 'Immunohistochemistry', 'Male', 'Mice', 'Mice, Inbred C3H'] | 11,140,454 | [['B01.050'], ['A03.556.124.526.209', 'A03.556.249.249.209'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C01.610.432.396', 'C01.610.752.049.328', 'C06.405.205.331.312', 'C06.405.469.300.312', 'C06.405.469.452.396'], ['B01.046.500.100.700.335.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.050.40... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Subchronic and developmental toxicity of aromatic extracts. | Aromatic extracts (AEs; distillate AEs [DAEs] and residual AEs [RAEs]) are complex, highly viscous liquid petroleum streams with variable compositions derived by extraction of aromatic compounds from distillate and residual petroleum fractions from a vacuum distillation tower, respectively. The DAEs generally contain s... | ['Animals', 'Carcinogens', 'Dose-Response Relationship, Drug', 'Endpoint Determination', 'Female', 'Fetal Development', 'Male', 'Micronucleus Tests', 'No-Observed-Adverse-Effect Level', 'Petroleum', 'Polycyclic Aromatic Hydrocarbons', 'Rats', 'Rats, Sprague-Dawley', 'Reproduction', 'Skin', 'Toxicity Tests, Subchronic'] | 24,567,345 | [['B01.050'], ['D27.888.569.100'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.315'], ['G07.345.500.325.235', 'G08.686.784.170.157'], ['E05.393.560.598'], ['E05.940.600', 'G07.690.936.750'], ['D20.345.630', 'N06.230.132.258.630'], ['D02.455.426.559.847', 'D04.615'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Influence of treatment time and pulse frequency on Salmonella Enteritidis, Escherichia coli and Listeria monocytogenes populations inoculated in melon and watermelon juices treated by pulsed electric fields. | Consumption of unpasteurized melon and watermelon juices has caused several disease outbreaks by pathogenic microorganisms worldwide. Pulsed electric field (PEF) has been recognized as a technology that may inactivate those bacteria present in fluid food products at low temperatures. Hence, PEF treatment at 35 kV/cm, 4... | ['Citrullus', 'Colony Count, Microbial', 'Consumer Product Safety', 'Cucurbitaceae', 'Electric Stimulation', 'Escherichia coli', 'Food Contamination', 'Food Preservation', 'Humans', 'Listeria monocytogenes', 'Salmonella enteritidis', 'Time Factors'] | 17,512,997 | [['B01.650.940.800.575.912.250.300.140'], ['E01.370.225.875.220', 'E05.200.875.220'], ['N06.850.210'], ['B01.650.940.800.575.912.250.300'], ['E05.723.402'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['J01.576.423.850.700'], ['B01.0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Sonochemical decomposition of levofloxacin in aqueous solution. | The decomposition of levofloxacin was performed in an aqueous solution under ultrasound irradiation. The effect of operating conditions, including pH value, reaction time, initial concentration, and ultrasound power on the chemical oxygen demand (COD) removal rate was examined at room temperature (23 +/- 2 degrees C). ... | ['Anti-Bacterial Agents', 'Carbon Tetrachloride', 'Hydrogen-Ion Concentration', 'Levofloxacin', 'Ofloxacin', 'Ultrasonics', 'Waste Disposal, Fluid', 'tert-Butyl Alcohol'] | 20,853,748 | [['D27.505.954.122.085'], ['D02.455.526.439.150'], ['G02.300'], ['D03.633.100.810.835.322.500.500'], ['D03.633.100.810.835.322.500'], ['H01.671.031.849'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D02.033.415.110.855', 'D10.289.110.855']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Prediction of risk for hemodynamic compromise during percutaneous transluminal coronary angioplasty. | The availability of circulatory support devices has increased the importance of accurately identifying patients at risk for hemodynamic compromise during percutaneous transluminal coronary angioplasty (PTCA). Accordingly, prospective evaluation of 3 criteria to predict hemodynamic compromise (defined as a decrease in s... | ['Aged', 'Angioplasty, Balloon, Coronary', 'Blood Pressure', 'Cohort Studies', 'Coronary Angiography', 'Coronary Disease', 'Female', 'Hemodynamics', 'Humans', 'Male', 'Multivariate Analysis', 'Regression Analysis', 'Risk Factors', 'Sensitivity and Specificity', 'Ventricular Function, Left'] | 1,466,320 | [['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Natural history of varicocele management in the era of intracytoplasmic sperm injection. | OBJECTIVE: To evaluate the outcomes of infertile couples with varicocele.DESIGN: Retrospective study.SETTING: University infertility clinic.PATIENT(S): Six hundred ten consecutive infertile couples in whom the man was found to have a clinical varicocele.INTERVENTION(S): Microsurgical varicocelectomy and assisted reprod... | ['Adult', 'Choice Behavior', 'Female', 'Humans', 'Infertility, Male', 'Male', 'Patient Acceptance of Health Care', 'Pregnancy', 'Pregnancy Rate', 'Retrospective Studies', 'Sperm Count', 'Sperm Injections, Intracytoplasmic', 'Sperm Motility', 'Treatment Outcome', 'Urologic Surgical Procedures, Male', 'Varicocele'] | 18,222,427 | [['M01.060.116'], ['F02.463.785.373.346'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365.700'], ['F01.100.150.750.500', 'F01.145.488.887.500', 'N05.300.150.800.500'], ['G08.686.784.769'], ['E05.318.308.985.775', 'G08.686.705', 'N01.224.935.849', 'N06.850.505.400.975.775', 'N06.850.520.308.985.775'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Blubber transcriptome response to acute stress axis activation involves transient changes in adipogenesis and lipolysis in a fasting-adapted marine mammal. | Stress can compromise an animal's ability to conserve metabolic stores and participate in energy-demanding activities that are critical for fitness. Understanding how wild animals, especially those already experiencing physiological extremes (e.g. fasting), regulate stress responses is critical for evaluating the impac... | ['Adipogenesis', 'Adrenocorticotropic Hormone', 'Animals', 'Aquatic Organisms', 'Gene Expression Profiling', 'Lipolysis', 'Seals, Earless', 'Sequence Analysis, RNA', 'Stress, Physiological'] | 28,186,107 | [['G04.152.149'], ['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['B01.050'], ['B05.080', 'G16.500.275.725.500.650.075'], ['E05.393.332'], ['G02.111.534', 'G03.458.500... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bacteria induced shell disease of lobsters (Homarus americanus). | Chitin degrading species of bacteria in the genera Pseudomonas, Vibrio, and Beneckea were cultured from the lesions of lobsters (Homarus americanus) with a shell disease. A species of bacterium of the genus Vibrio (Beneckea) produced necrosis characteristics of shell disease in experimental lobsters when the integument... | ['Animals', 'Bacteria', 'Nephropidae', 'Pseudomonas', 'Temperature', 'Vibrio'] | 633,512 | [['B01.050'], ['B03'], ['B01.050.500.131.365.190.550'], ['B03.440.400.425.625.625', 'B03.660.250.580.590'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['B03.440.450.900.859', 'B03.660.250.830.830']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Clinical experience in late antiquity: Alexander of Tralles and the therapy of epilepsy. | Alexander of Tralles, writing in the late sixth century, combined his wide-ranging practical knowledge with earlier medical theories. This article shows how clinical experience is used in Alexander's works by concentrating on his therapeutic advice on epilepsy and, in particular, on pharmacology and the group of so-cal... | ['Complementary Therapies', 'Epilepsy', 'History, Medieval', 'Humans', 'Pharmacology'] | 25,045,178 | [['E02.190'], ['C10.228.140.490'], ['K01.400.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.158.703', 'H02.628']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Humanities [K]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The importance of standardised radiographs when assessing hip dysplasia. | The reliability of radiological criteria in the diagnosis of congenital dislocation of the hip is discussed. In a review of 20 normal infant patients the variability of the radiographic relationship between the ossific nucleus of the proximal femoral epiphysis and the acetabulum is identified. Hip arthrography in 10 pa... | ['Arthrography', 'Femur Head', 'Hip Dislocation', 'Humans', 'Infant', 'Posture'] | 2,081,675 | [['E01.370.350.700.070'], ['A02.835.232.043.150.343'], ['C05.550.518.384', 'C26.289.384', 'C26.531.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G11.427.695']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cryoablation of atrioventricular nodal reentrant tachycardia in children and adolescents: improved long-term outcomes with increasing experience. | BACKGROUND: Cryoablation is increasingly used for the treatment of atrioventricular nodal reentrant tachycardia (AVNRT). There are limited data regarding its efficacy and late outcomes in the pediatric population.METHODS: We reviewed the clinical records of 70 consecutive pediatric and adolescent patients (mean age: 12... | ['Adolescent', 'Child', 'Child, Preschool', 'Cryosurgery', 'Follow-Up Studies', 'Humans', 'Recurrence', 'Retrospective Studies', 'Risk Factors', 'Tachycardia, Atrioventricular Nodal Reentry', 'Treatment Outcome', 'Young Adult'] | 23,685,655 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E04.014.180'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.291.937'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
HLA-J, a second inactivated class I HLA gene related to HLA-G and HLA-A. Implications for the evolution of the HLA-A-related genes. | Ragoussis and co-workers (Genomics 4:301) previously described a class I HLA gene (now designated HLA-J) that maps to within 50 kb of HLA-A. The nucleotide sequences of three HLA-J alleles are reported here. Comparison of the nucleotide sequences of HLA-J alleles shows this gene is more related to HLA-G, A, and H than ... | ['Alleles', 'Amino Acid Sequence', 'Base Sequence', 'Biological Evolution', 'Chromosome Deletion', 'Consensus Sequence', 'Enhancer Elements, Genetic', 'Exons', 'Genes, MHC Class I', 'Histocompatibility Antigens Class I', 'Humans', 'Molecular Sequence Data', 'Polymorphism, Genetic', 'Promoter Regions, Genetic', 'Pseudog... | 1,602,142 | [['G05.360.340.024.340.030'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045', 'G16.075'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['G02.111.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Molecular mechanism of action of Pelargonidin-3-O-glucoside, the main anthocyanin responsible for the anti-inflammatory effect of strawberry fruits. | Fragaria x ananassa Duch., popularly called strawberry, is known for its worldwide consumption and important biological activities, and these effects are related to its high concentration of anthocyanins. Pelargonidin-3-O-glucoside (P3G) is a major anthocyanin found in strawberry, and was evaluated for its anti-inflamm... | ['Adenosine Deaminase', 'Animals', 'Anthocyanins', 'Anti-Inflammatory Agents, Non-Steroidal', 'Cell Movement', 'Female', 'Fragaria', 'Fruit', 'Leukocytes', 'Mice', 'Mitogen-Activated Protein Kinases', 'NF-kappa B', 'Peroxidase', 'Phosphorylation', 'Plant Extracts', 'Pleurisy', 'Transcription Factor AP-1'] | 29,277,228 | [['D08.811.277.151.486.075'], ['B01.050'], ['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['G04.198', 'G07.568.500.180'], ['B01.650.940.800.575.912.250.859.937.500.266'], ['A18.024.500', 'G0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Atomic force microscopy reveals DNA bending during group II intron ribonucleoprotein particle integration into double-stranded DNA. | The mobile Lactococcus lactis Ll.LtrB group II intron integrates into DNA target sites by a mechanism in which the intron RNA reverse splices into one DNA strand while the intron-encoded protein uses a C-terminal DNA endonuclease domain to cleave the opposite strand and then uses the cleaved 3' end to prime reverse tra... | ['Bacterial Proteins', 'Base Sequence', 'Binding Sites', 'DNA, Bacterial', 'Escherichia coli', 'Escherichia coli Proteins', 'Introns', 'Lactococcus lactis', 'Macromolecular Substances', 'Microscopy, Atomic Force', 'Models, Biological', 'Mutation', 'Nucleic Acid Conformation', 'Protein Binding', 'Ribonucleoproteins'] | 17,029,398 | [['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['B03.353.750.737.500.400', 'B03.510.400.800.500.400', 'B03.510.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Lethal, neonatal, short-limbed platyspondylic dwarfism. A further variant? | A stillborn short-limbed platyspondylic dwarf is described. Detailed analysis of the X-ray and histological characteristics of bone and cartilage suggest that this infant represents a previously unreported variant of short-limbed platyspondylic dwarfism. The designation "Luton variant" is suggested. | ['Cartilage', 'Dwarfism', 'Female', 'Fetal Death', 'Humans', 'Pregnancy', 'Radiography'] | 7,173,874 | [['A02.165', 'A10.165.382'], ['C05.116.099.343', 'C16.320.240', 'C19.297'], ['C13.703.223', 'C23.550.260.585'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['E01.370.350.700']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Localisation of neuropeptide Y in nerves of the rat cardiovascular system and the effect of 6-hydroxydopamine. | The distribution of neuropeptide Y (NPY) in the rat cardiovascular system has been examined by radioimmunoassay, chromatographic analysis of tissue extracts, and immunocytochemistry. High concentrations of NPY were identified throughout the heart and within the major blood vessels of the rat in particular in the renal ... | ['Adrenergic Fibers', 'Animals', 'Cardiovascular System', 'Chromatography, High Pressure Liquid', 'Female', 'Hydroxydopamines', 'Nerve Tissue Proteins', 'Neuropeptide Y', 'Oxidopamine', 'Radioimmunoassay', 'Rats', 'Rats, Inbred Strains'] | 3,930,070 | [['A08.675.100.500', 'A08.675.542.075', 'A11.671.501.075'], ['B01.050'], ['A07'], ['E05.196.181.400.300'], ['D02.092.311.342.478', 'D02.455.426.559.389.657.166.175.342.478'], ['D12.776.631'], ['D12.644.400.500', 'D12.776.631.650.500'], ['D02.092.311.342.478.650', 'D02.455.426.559.389.657.166.175.342.478.650'], ['E01.37... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Regulation of enzyme activity in adsorptive enzyme systems. III. Interaction of pig muscle lactate dehydrogenase with F-actin]. | The binding of pig skeletal muscle lactate dehydrogenase by F-actin has been studied using the sedimentation method in 10 mM Tris-acetate buffer, pH 6.0 at 20 degrees C. Adsorption capacity of F-actin is equal to (1 +/- 0.1) . 10(-5) moles of lactate dehydrogenase per 1 g of actin. NADH decreases the affinity of F-acti... | ['Actins', 'Animals', 'Enzymes, Immobilized', 'Kinetics', 'L-Lactate Dehydrogenase', 'Muscles', 'Swine'] | 6,855,766 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['D08.811.180', 'D12.776.463.500'], ['G01.374.661', 'G02.111.490'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['A02.633', 'A10.690'], ['B01.050.150.900.649.313.500.880']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A genetic coding variant rs72474224 in GJB2 is associated with clinical features of psoriasis vulgaris in a Chinese Han population. | Our recent targeted sequencing study identified a missense single-nucleotide polymorphism rs72474224 (c.324C>T) in GJB2. To investigate the correlation between rs72474224 (c.324C>T) and subphenotypes of psoriasis, genotype data for rs72474224 (c.324C>T, p.Val37Ile) was analyzed in 9946 cases and 9906 controls. The addi... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Alleles', 'Asian Continental Ancestry Group', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Connexin 26', 'Connexins', 'Exons', 'Female', 'Gene Expression', 'Gene Frequency', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Genotype', 'Hu... | 26,104,599 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G05.360.340.024.340.030'], ['M01.686.508.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['D12.776.543.585.250.100'], ['D12.776.543.585.250'], ['G05.360.340.024.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cathepsin A inhibition attenuates myocardial infarction-induced heart failure on the functional and proteomic levels. | BACKGROUND: Myocardial infarction (MI) is a major cause of heart failure. The carboxypeptidase cathepsin A is a novel target in the treatment of cardiac failure. We aim to show that recently developed inhibitors of the protease cathepsin A attenuate post-MI heart failure.METHODS: Mice were subjected to permanent left a... | ['Animals', 'Cathepsin A', 'Cell Line', 'Disease Models, Animal', 'Heart Failure', 'Heart Ventricles', 'Ligation', 'Male', 'Mice, Inbred C57BL', 'Myocardial Infarction', 'Organ Size', 'Peptide Mapping', 'Protease Inhibitors', 'Proteome', 'Proteomics', 'Rats'] | 27,246,731 | [['B01.050'], ['D08.811.277.656.224.062', 'D08.811.277.656.350.245.260', 'D08.811.277.656.959.200'], ['A11.251.210'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C14.280.434'], ['A07.541.560'], ['E04.426'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['C14.280.647.500', 'C14... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Lectin labeling of sprouting neurons. III. Type-specific glycoconjugates on growth cones of different origin. | Ferritin conjugates of various lectins were used to determine the densities of surface carbohydrates on nerve growth cones produced by different classes of neuron. These neurons, from superior cervical and dorsal root ganglia, spinal cord, olfactory bulb, and cerebellum of the fetal rat, were grown as explant cultures,... | ['Animals', 'Concanavalin A', 'Female', 'Lectins', 'Microscopy, Electron', 'Neuraminidase', 'Neurons', 'Pregnancy', 'Rats', 'Rats, Inbred Strains', 'Receptors, Mitogen', 'Ricin', 'Wheat Germ Agglutinins'] | 6,548,457 | [['B01.050'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D12.776.503'], ['E01.370.350.515.402', 'E05.595.402'], ['D08.811.277.450.692'], ['A08.675', 'A11.671'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D12.776.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Auditory sensitivity in the bullhead catfish (Ictalurus nebulosis). | The auditory sensitivity of 4 specimens of the bullhead catfish (Ictalurus nebulosis) was determined by shock-avoidance training in an aquatic shuttle box. The range of hearing extended from 100 to 4000 cycles per second, with the maximum sensitivity around 600 to 700 cycles per second. | ['Animals', 'Auditory Threshold', 'Avoidance Learning', 'Conditioning, Psychological', 'Fishes'] | 5,261,032 | [['B01.050'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['F02.463.425.097', 'F02.463.785.373.173'], ['F02.463.425.179'], ['B01.050.150.900.493']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adalimumab safety and mortality rates from global clinical trials of six immune-mediated inflammatory diseases. | OBJECTIVES: Clinical trials of tumour necrosis factor antagonists have raised questions about the potential risk of certain serious adverse events (SAE). To assess the safety of adalimumab in rheumatoid arthritis (RA) over time and across five other immune-mediated inflammatory diseases and to compare adalimumab malign... | ['Adalimumab', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Humanized', 'Antirheumatic Agents', 'Arthritis', 'Arthritis, Rheumatoid', 'Crohn Disease', 'Drug Administration Schedule', 'Humans', 'Immunosuppressive Agents', 'Neoplasms', 'Opportunistic Infections', 'Tumor Necrosis Factor-alpha'] | 19,147,611 | [['D12.776.124.486.485.114.224.060.250', 'D12.776.124.790.651.114.224.060.250', 'D12.776.377.715.548.114.224.200.250'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200']... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Agenesis of the corpus callosum revealed by computerized tomography. | Computerized tomography is a new, safe, non-invasive method of diagnosing intracranial disorders. It has been used in the detection of intracranial tumors, hydrocephalus, hemorrhages, atrophy, abscesses and subdural hematomata. Two cases of agenesis of the corpus callosum are presented, in which the diagnosis was made ... | ['Agenesis of Corpus Callosum', 'Brain', 'Child, Preschool', 'Computers', 'Corpus Callosum', 'Humans', 'Infant', 'Male', 'Tomography, X-Ray'] | 1,278,623 | [['C10.500.034', 'C16.131.666.034', 'C23.300.008'], ['A08.186.211'], ['M01.060.406.448'], ['L01.224.230.260'], ['A08.186.211.200.885.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E01.370.350.700.810', 'E01.370.350.825.810']] | ['Diseases [C]', 'Anatomy [A]', 'Named Groups [M]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Two new compounds from the roots of Lysidice rhodostegia. | Two new compounds, lysidicin D (1) and lysidicin E (2), were isolated from the roots of Lysidice rhodostegia. Their structures were elucidated by means of spectroscopic methods. Among them compound 1 showed potent anti-oxidant activity on in vitro. | ['Antioxidants', 'Fabaceae', 'Phenanthrenes', 'Phloroglucinol', 'Plant Roots'] | 17,701,568 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B01.650.940.800.575.912.250.401'], ['D02.455.426.559.847.723', 'D04.615.723'], ['D02.455.426.559.389.657.684'], ['A18.400']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fixation and staining of planaria for histological study. | Fixation and staining of planaria can affect the interpretation of histopathological changes following their exposure to various agents. We assessed several fixation protocols with various stains in planaria to determine an optimal combination. Planaria were fixed in each of the following: 10% neutral buffered formalin... | ['Animals', 'Histological Techniques', 'Planarians', 'Staining and Labeling', 'Tissue Fixation'] | 7,548,433 | [['B01.050'], ['E01.370.225.750', 'E05.200.750'], ['B01.050.500.500.736.847.610'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.500.620.670', 'E05.200.750.600.670'], ['E01.370.225.500.620.760.720', 'E01.370.225.750.600.760.720', 'E05.200.500.620.760.720', 'E05.200.750.600.760.720']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Designing long-T2 suppression pulses for ultrashort echo time imaging. | Ultrashort echo time (UTE) imaging has shown promise as a technique for imaging tissues with T2 values of a few milliseconds or less. These tissues, such as tendons, menisci, and cortical bone, are normally invisible in conventional magnetic resonance imaging techniques but have signal in UTE imaging. They are difficul... | ['Adipose Tissue', 'Ankle', 'Brain', 'Computer Simulation', 'Echo-Planar Imaging', 'Humans', 'Phantoms, Imaging', 'Time Factors'] | 16,724,304 | [['A10.165.114'], ['A01.378.610.050'], ['A08.186.211'], ['L01.224.160'], ['E01.370.350.825.500.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.671'], ['G01.910.857']] | ['Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Engineering of factors determining alpha-amylase and cyclodextrin glycosyltransferase specificity in the cyclodextrin glycosyltransferase from Thermoanaerobacterium thermosulfurigenes EM1. | The starch-degrading enzymes alpha-amylase and cyclodextrin glycosyltransferase (CGTase) are functionally and structurally closely related, with CGTases containing two additional domains (called D and E) compared to the three domains of alpha-amylases (A, B and C). Amino acid residue 196 (Thermoanaerobacterium thermosu... | ['Amino Acid Sequence', 'Binding Sites', 'Cyclodextrins', 'DNA Primers', 'Glucosyltransferases', 'Gram-Negative Anaerobic Bacteria', 'Humans', 'Kinetics', 'Models, Molecular', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Point Mutation', 'Polymerase Chain Reaction', 'Protein Conformation', 'Sequence Alignm... | 9,654,055 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['D04.345.103', 'D09.301.915.400.375', 'D09.698.365.855.400.375'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D08.811.913.400.450.460'], ['B03.440.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Brazilian HIV-infected population: assessment of the needs of endodontic treatment in the post-highly active antiretroviral therapy era. | INTRODUCTION: The effects of highly active antiretroviral therapy (HAART) on the prevalence of endodontic diseases in HIV-infected individuals have not been reported.METHODS: The purpose of this study was to determine and compare sex, age, need for root canal treatment, CD4 and CD8 lymphocyte counts, HIV viral load, an... | ['Adolescent', 'Adult', 'Aged', 'Antiretroviral Therapy, Highly Active', 'Brazil', 'CD4 Lymphocyte Count', 'CD4-CD8 Ratio', 'Chi-Square Distribution', 'Child', 'Dental Care for Chronically Ill', 'Dental Pulp Diseases', 'Female', 'HIV Infections', 'Health Services Needs and Demand', 'Humans', 'Male', 'Medication Adheren... | 19,720,212 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.319.310.075'], ['Z01.107.757.176'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500.150', 'G04.140.107.595.500.150', 'G09.188.105.595.500.15... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Molecular determinants of the subcellular localization of the Drosophila Bcl-2 homologues DEBCL and BUFFY. | The Bcl-2-family of proteins localize to intracellular membranes via a C-terminal hydrophobic membrane anchor (MA) domain, to exert their antiapoptotic or proapoptotic functions. In Drosophila, both Bcl-2 family members, DEBCL and BUFFY, contain an MA. In DEBCL the MA is necessary for the localization of protein to mit... | ['Amino Acid Sequence', 'Animals', 'Apoptosis', 'COS Cells', 'Cell Nucleus', 'Chlorocebus aethiops', 'Drosophila Proteins', 'Drosophila melanogaster', 'Endoplasmic Reticulum', 'Humans', 'Membrane Proteins', 'Mice', 'Mitochondrial Membranes', 'Molecular Sequence Data', 'Mutant Proteins', 'Mutation', 'NIH 3T3 Cells', 'Nu... | 17,205,077 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G04.146.954.035'], ['A11.251.210.172.500', 'A11.329.228.220'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['A11.284.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
G2 phase-specific proteins of HeLa cells. | The objective of this study was to determine if HeLa cells irreversibly arrested in G2 phase of the cell cycle by a brief exposure to a nitrosourea compound were deficient in certain proteins when compared with G2-synchronized cells. Total cellular proteins of G2-synchronized, G2-arrested, and S phase-synchronized cell... | ['Cell Cycle', 'Cell Fusion', 'DNA Replication', 'HeLa Cells', 'Mitosis', 'Nitrosourea Compounds', 'Proteins', 'RNA'] | 282,623 | [['G04.144'], ['E05.242.307', 'G04.155'], ['G02.111.225', 'G05.226'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['G04.144.220.220.781', 'G05.113.220.781'], ['D02.065.950.594', 'D02.654.692'], ['D12.776'], ['D13.444.735']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increasing long-term response by selecting for favorable minor alleles. | Long-term response of genomic selection can be improved by considering allele frequencies of selected markers or quantitative trait loci (QTLs). A previous formula to weight allele frequency of favorable minor alleles was tested, and 2 new formulas were developed. The previous formula used nonlinear weights based on sq... | ['Alleles', 'Animals', 'Breeding', 'Cattle', 'Computer Simulation', 'Female', 'Gene Frequency', 'Genotype', 'Inbreeding', 'Male', 'Models, Genetic', 'Quantitative Trait Loci', 'Selection, Genetic'] | 24,505,495 | [['G05.360.340.024.340.030'], ['B01.050'], ['E05.820.150', 'G05.090'], ['B01.050.150.900.649.313.500.380.271'], ['L01.224.160'], ['G05.330'], ['G05.380'], ['E05.820.150.520', 'G05.090.403'], ['E05.599.395.397'], ['G05.360.340.024.380.937'], ['G05.783']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Plasma and membrane Ca2+ and Mg2+ concentrations in normal pregnancy and in preeclampsia. | OBJECTIVE: Changes in intracellular Ca2+ and Mg2+ concentrations seem to be involved in the pathogenesis of preeclampsia, whereas the role of cell membranes has not been studied in detail yet. To investigate the changes in Ca2+ and Mg2+ metabolism in normal pregnancy and preeclampsia, plasma and membrane Ca2+ and Mg2+ ... | ['Blood Pressure', 'Calcium', 'Erythrocyte Membrane', 'Female', 'Humans', 'Magnesium', 'Pre-Eclampsia', 'Pregnancy', 'Reference Values', 'Spectrophotometry, Atomic'] | 9,736,795 | [['E01.370.600.875.249', 'G09.330.380.076'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['C13.703.395.249'], ['G08.686.784.769'], ['E05.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Detection of Epstein-Barr virus genome in ocular tissues. | BACKGROUND: Epstein-Barr virus (EBV) is a ubiquitous mucosal pathogen with a propensity for lifelong, asymptomatic persistence. Because of reported association between EBV and ocular inflammatory disorders, we tested ocular tissues from normal eyes for presence of the EBV genome.METHODS: Ten freshly harvested cadaveric... | ['Cadaver', 'Carrier State', 'DNA, Viral', 'Eye', 'Eye Infections, Viral', 'Genome, Viral', 'Herpesviridae Infections', 'Herpesvirus 4, Human', 'Humans', 'Polymerase Chain Reaction', 'Tumor Virus Infections'] | 8,618,773 | [['C23.550.260.224'], ['N06.850.520.169'], ['D13.444.308.568'], ['A01.456.505.420', 'A09.371'], ['C01.375.725', 'C01.925.325', 'C11.294.800'], ['G05.360.340.358.840'], ['C01.925.256.466'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Six new species and new records of the spider genus <i>Chrosiothes</i> from Brazil with the description of the female of <i>Chrosiothes</i> <i>venturosus</i> Marques & Buckup, 1997 (Araneae, Theridiidae, Spintharinae). | The spider genus Chrosiothes Simon, 1894 currently comprises 21 described species. Spiders of this genus are mainly known from the Neotropical Region, but are poorly studied in Brazil. In this paper six new species of Chrosiothes are described from Brazil: Chrosiothes diabolicus new species; Chrosiothes carajaensis new... | ['Animal Distribution', 'Animal Structures', 'Animals', 'Brazil', 'Female', 'Spiders'] | 29,242,474 | [['F01.145.113.069', 'G16.049'], ['A13'], ['B01.050'], ['Z01.107.757.176'], ['B01.050.500.131.166.803']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Surgical management of tetralogy of Fallot with absent pulmonary valve. | Tetralogy of Fallot and absent pulmonary valve (T-APV) is associated with massively dilated pulmonary arteries that cause tracheobronchial compression in the newborn and heart failure and cyanosis in older patients. Corrective operations have been attended by high mortality rates due to pulmonary insufficiency causing ... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Pulmonary Valve', 'Tetralogy of Fallot'] | 6,654,971 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A07.541.510.738'], ['C14.240.400.849', 'C14.280.400.849', 'C16.131.240.400.849']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Primary adenocarcinoma in the urethrorectal fistula. | A 60-year-old Japanese man was hospitalized because of urinary leakage from the anus on October 3, 1994. Retrograde urethrography detected a fistula between the bulbous urethra and the rectum. Urethrocystoscopy revealed a tumor on the urethrorectal fistula. Tumor biopsy showed a well differentiated adenocarcinoma. Cyst... | ['Adenocarcinoma', 'Fistula', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Rectal Diseases', 'Rectal Neoplasms', 'Urethra', 'Urethral Diseases', 'Urethral Neoplasms', 'Urinary Fistula'] | 9,179,677 | [['C04.557.470.200.025'], ['C23.300.575'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700'], ['C06.405.469.860'], ['C04.588.274.476.411.307.790', 'C06.301.371.411.307.790', 'C06.405.249.411.307.790', 'C06.405.469.491.307.790', 'C06.405.469.860.180.500'], ['A05.360.444.492.726', ... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Social responsibilities in pediatrics and their realization in Czechoslovakia. 3. Social aspects of the pediatric care of children at public facilities]. | A survey is given on the standard co-operation of the paediatrician in the care of children in cr?ches, in infant institutions, in children's homes, in children's psychiatric hospitals as well as in sanatoria. | ['Child', 'Child Day Care Centers', 'Child Health Services', 'Child, Institutionalized', 'Child, Preschool', 'Czechoslovakia', 'Humans', 'Infant', 'Pediatrics', 'Referral and Consultation'] | 2,622,700 | [['M01.060.406'], ['J03.160', 'N02.421.143.098'], ['N02.421.143.130'], ['M01.643.364'], ['M01.060.406.448'], ['Z01.586.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['H02.403.670'], ['N04.452.758.849']] | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 |
31p nuclear relaxation studies of para- and diamagnetic cobalamins in their two isomeric forms. | A new, naturally occurring isomeric form of vitamin B-12 was reported by us earlier (Katada, M., Tyagi, S., Nath, A., Petersen, R.L. and Gupta, R.K. (1979) Biochim. Biophys. Acta 584, 149-163). The M?ssbauer parameters of various derivatives of vitamin B-12, including the one-electron reduced species, cob(II)-alamin (v... | ['Isomerism', 'Magnetic Resonance Spectroscopy', 'Models, Chemical', 'Vitamin B 12'] | 7,236,717 | [['G02.111.570.685', 'G02.607.445'], ['E05.196.867.519'], ['E05.599.495'], ['D03.383.129.578.840.437.777', 'D03.633.400.909.437.777', 'D04.345.783.437.777']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Kinetochore-Microtubule Coupling Machinery Is Repurposed in Sensory Nervous System Morphogenesis. | Dynamic coupling of microtubule ends to kinetochores, built on the centromeres of chromosomes, directs chromosome segregation during cell division. Here, we report that the evolutionarily ancient kinetochore-microtubule coupling machine, the KMN (Knl1/Mis12/Ndc80-complex) network, plays a critical role in neuronal morp... | ['Animals', 'Caenorhabditis elegans', 'Caenorhabditis elegans Proteins', 'Dendrites', 'Embryo, Nonmammalian', 'Embryonic Development', 'Kinetochores', 'Microtubules', 'Mitosis', 'Morphogenesis', 'Nervous System', 'Sensory Receptor Cells'] | 30,827,898 | [['B01.050'], ['B01.050.500.500.294.400.875.660.250.250'], ['D12.776.419.500'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['A13.350', 'A16.331'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['A11.284.430.106.279.345.190.160.165.500', 'G05.360.160.165.500'], ['A11.284.430.214.190.750.602'], ['G04.144.220.22... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adult-type T-cell lymphoma in an adolescent with human T-lymphotropic virus type 1 seropositivity. | Recently, a form of T-cell lymphoma associated with seropositivity for human T-lymphotrop virus type 1 (HTLV-1) antibody has been described in the adult population. The lymphoma frequently presents with massive hepatosplenomegaly, lymphadenopathy and circulating malignant cells, with a normal bone marrow. HTLV-1-associ... | ['Adolescent', 'HTLV-I Antibodies', 'Humans', 'Leukemia-Lymphoma, Adult T-Cell', 'Male'] | 2,747,594 | [['M01.060.057'], ['D12.776.124.486.485.114.254.150.500', 'D12.776.124.790.651.114.254.150.500', 'D12.776.377.715.548.114.254.150.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.428.580.100', 'C15.604.515.560.575.100', 'C20.683.515.528.582.100']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Successful pregnancy in a kidney transplant recipient with chronic hepatitis B virus infection. | Overall success rate of pregnancies in kidney transplant recipients is higher than 90% if pregnancy goes beyond the 1st trimester. Risks to mother include hypertension, preeclampsia, infections, and worsening proteinuria, and those to the fetus are prematurity, intrauterine growth retardation, and low birth weight. Hep... | ['Adult', 'Female', 'Hepatitis B virus', 'Hepatitis B, Chronic', 'Humans', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Lamivudine', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Reverse Transcriptase Inhibitors', 'Treatment Outcome', 'Viral Load'] | 24,072,155 | [['M01.060.116'], ['B04.280.375.650.425', 'B04.450.390.650.425'], ['C01.221.250.500.100', 'C01.925.256.430.400.100', 'C01.925.440.435.100', 'C06.552.380.350.100', 'C06.552.380.705.437.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E02.870.500', 'E04... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Robotic single-port cholecystectomy using a new platform: initial clinical experience. | BACKGROUND: The technique of single-port laparoscopy was developed over the past years in an attempt to reduce the invasiveness of surgery. A reduction of incisions and their overall size might result in enhanced postoperative cosmesis and potentially reduce pain when compared to conventional techniques. While manual s... | ['Adult', 'Aged', 'Cholecystectomy, Laparoscopic', 'Equipment Design', 'Female', 'Gallbladder Diseases', 'Humans', 'Male', 'Middle Aged', 'Pain, Postoperative', 'Postoperative Complications', 'Prospective Studies', 'Robotics', 'Treatment Outcome', 'Young Adult'] | 21,948,180 | [['M01.060.116'], ['M01.060.116.100'], ['E04.210.120.172.140', 'E04.502.250.520.160'], ['E05.320'], ['C06.130.564'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767.700', 'C23.888.592.612.832'], ['C23.550.767'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 |
Efficacy of CD14⁺ blood monocytes/macrophages isolation: positive versus negative MACS protocol. | Cardiovascular implants such as stents or artificial vascular grafts established in clinical application to date are generally designed as long-term implants. An important requirement for the successful application of these devices is the haemocompatibility of their interface to the blood stream, which often is approac... | ['Cell Separation', 'Flow Cytometry', 'Humans', 'Lipopolysaccharide Receptors', 'Macrophages', 'Magnetics', 'Monocytes'] | 21,876,234 | [['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.395.550.448.100', 'D12.776.543... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The role of education in improving physicians' professional use of economic evaluations of health interventions: some evidence from a cross-sectional survey in Italy. | A cross-sectional survey was carried out on a random sample of Italian physicians through a self-administered questionnaire to describe knowledge, attitudes, and professional behavior toward economic evaluations of health interventions. A response rate of 74.1% was achieved (760 questionnaires). Although many physician... | ['Adult', 'Cost-Benefit Analysis', 'Cross-Sectional Studies', 'Delivery of Health Care', 'Education, Medical, Continuing', 'Female', 'Humans', 'Italy', 'Male', 'Middle Aged', 'Physicians'] | 19,679,635 | [['M01.060.116'], ['N03.219.151.125'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N04.590.374', 'N05.300'], ['I02.358.212.350', 'I02.358.399.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['M01.060.116.630'], ['M01.526.485.810', 'N02.360.810']] | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Creating a social movement for health. | NHS chief executive Simon Stevens is among leaders to have identified the need for social movements in health, and for the development of a culture of health in our society. | ['Humans', 'Public Health', 'Social Conditions', 'United Kingdom'] | 27,808,640 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['I01.880.853.450', 'N01.824.827'], ['Z01.542.363']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
A novel fiber composite ingredient incorporated into a beverage and bar blunts postprandial serum glucose and insulin responses: a randomized controlled trial. | Previous research supports that consumption of resistant starch and guar gum independently influences insulin-mediated glucose responses to meals. This research assessed a novel co-processed fiber composite (FC) ingredient comprising whole-grain high-amylose maize flour and viscous guar gum on glucose and insulin respo... | ['Adolescent', 'Adult', 'Amylose', 'Beverages', 'Blood Glucose', 'Cross-Over Studies', 'Dietary Fiber', 'Double-Blind Method', 'Female', 'Flour', 'Galactans', 'Humans', 'Insulin', 'Male', 'Mannans', 'Meals', 'Plant Gums', 'Polysaccharides', 'Postprandial Period', 'Whole Grains', 'Young Adult', 'Zea mays'] | 26,923,512 | [['M01.060.057'], ['M01.060.116'], ['D09.301.915.361', 'D09.698.365.855.361'], ['G07.203.100', 'J02.200'], ['D09.947.875.359.448.500'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
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