Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Light and electron microscopic studies on the pigmented epithelium and photoreceptors of the retina of common buzzard (Buteo buteo). | The current study is essentially carried out to reveal the histological and ultra-structural details of the retinal pigmented epithelium (RPE) and photoreceptors cell layers of a common buzzard (Buteo buteo). The recorded results revealed that the neural retina of common buzzard consisted of seven distinct cell layers.... | ['Animals', 'Cell Nucleus', 'Endoplasmic Reticulum, Rough', 'Endoplasmic Reticulum, Smooth', 'Falconiformes', 'Microscopy, Electron', 'Retinal Cone Photoreceptor Cells', 'Retinal Pigment Epithelium', 'Retinal Rod Photoreceptor Cells'] | 25,541,273 | [['B01.050'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.214.190.875.248.300', 'A11.284.430.214.190.875.811.740.300'], ['A11.284.430.214.190.875.248.310'], ['B01.050.150.900.248.815.350'], ['E01.370.350.515.402', 'E05.595.402'], ['A08.675.650.850.625.670.100', 'A08.675.650.915.937.670.100', 'A08.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phosphorylation of the Brome Mosaic Virus Capsid Regulates the Timing of Viral Infection. | UNLABELLED: The four brome mosaic virus (BMV) RNAs (RNA1 to RNA4) are encapsidated in three distinct virions that have different disassembly rates in infection. The mechanism for the differential release of BMV RNAs from virions is unknown, since 180 copies of the same coat protein (CP) encapsidate each of the BMV geno... | ['Bromovirus', 'Capsid Proteins', 'Cryoelectron Microscopy', 'Mass Spectrometry', 'Phosphorylation', 'Plants', 'Protein Processing, Post-Translational', 'Virion', 'Virus Diseases', 'Virus Replication'] | 27,334,588 | [['B04.715.081.080', 'B04.715.464.080', 'B04.820.578.282.080'], ['D12.776.964.970.600.550'], ['E01.370.350.515.402.150', 'E05.595.402.150'], ['E05.196.566'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['B01.650'], ['G02.111.660.871.790.600', 'G02.111.691.600', 'G03.734.871.790.600', 'G05.308.670.600'], ['A21.249'], ['C... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of obesity on coronary atherosclerosis and outcomes of percutaneous coronary intervention: grayscale and virtual histology intravascular ultrasound substudy of assessment of dual antiplatelet therapy with drug-eluting stents. | BACKGROUND: Obesity is a cardiovascular risk factor, but the obesity paradox in patients undergoing percutaneous coronary intervention is poorly understood.METHODS AND RESULTS: Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents (ADAPT-DES) was a prospective, multicenter study of patients undergoing drug-e... | ['Aged', 'Blood Vessel Prosthesis Implantation', 'Body Mass Index', 'Comorbidity', 'Coronary Artery Disease', 'Coronary Thrombosis', 'Coronary Vessels', 'Drug-Eluting Stents', 'Female', 'Follow-Up Studies', 'Humans', 'Imaging, Three-Dimensional', 'Male', 'Middle Aged', 'Obesity', 'Paclitaxel', 'Percutaneous Coronary In... | 25,552,564 | [['M01.060.116.100'], ['E04.100.814.868.500', 'E04.650.200'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['N05.715.350.225', 'N06.850.490.687'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['C14.280.647.250.290', 'C14.907.355.830.220', 'C14.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Effects of ethanol administration on cerebral non-protein sulfhydryl content in rats exposed to styrene vapour. | Glutathione (GSH) and other non-protein sulfhydryls (NPS) are known to protect cells from oxidative stress and from potentially toxic electrophiles formed by biotransformation of xenobiotics. This study examined the effect of a simultaneous administration of styrene and ethanol on NPS content and lipid peroxidation in ... | ['Administration, Inhalation', 'Animals', 'Brain', 'Drug Interactions', 'Ethanol', 'Glutathione', 'Glyoxylates', 'Lipid Peroxidation', 'Liver', 'Male', 'Mandelic Acids', 'Microsomes, Liver', 'Rats', 'Rats, Sprague-Dawley', 'Styrene', 'Styrenes', 'Sulfhydryl Compounds'] | 8,571,382 | [['E02.319.267.050'], ['B01.050'], ['A08.186.211'], ['G07.690.773.968'], ['D02.033.375'], ['D12.644.456.448'], ['D02.241.152.367'], ['G02.111.515', 'G03.295.531.587'], ['A03.620'], ['D02.241.223.475', 'D02.241.511.536'], ['A11.284.835.540.541'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The potential of photo-deposited silver coatings on Foley catheters to prevent urinary tract infections. | Catheter-associated urinary tract infection (CAUTI) represents one of the most common causes of morbidity and mortality. The resistance demonstrated by many microorganisms to conventional antibiotic therapies and the increasing health-care costs have recently encouraged the definition of alternative preventive strategi... | ['Biofilms', 'Coated Materials, Biocompatible', 'Escherichia coli', 'Klebsiella pneumoniae', 'Microscopy, Electron, Scanning', 'Proteus mirabilis', 'Silver', 'Ultraviolet Rays', 'Urinary Catheters'] | 27,612,730 | [['A20.593', 'G06.120'], ['D25.130.420', 'J01.637.051.130.420'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B03.440.450.425.425.600', 'B03.660.250.150.400.590'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['B03.440.450.425.600.501', 'B03.660.250.150.590.500'], ['D01.268.556.812', 'D01.268.956.843', ... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Rapid treatment of water contamined with atrazine and parathion with zero-valent iron. | The utility of fine-grained iron metal in the remediation of water contamined with Atrazine and Parathion was investigated. Batch procedures under water treatment conditions (ambient temperature and pH of approximately 7) indicated that these pesticides degrade rapidly in the presence of iron powder (40-60 mesh, 40 g/l... | ['Aerobiosis', 'Atrazine', 'Buffers', 'Chromatography, High Pressure Liquid', 'Herbicides', 'Hydrogen-Ion Concentration', 'Insecticides', 'Iron', 'Parathion', 'Spectrophotometry, Ultraviolet', 'Water Pollutants, Chemical', 'Water Supply'] | 10,467,726 | [['G02.111.017', 'G03.049'], ['D03.383.931.247'], ['D27.720.470.280'], ['E05.196.181.400.300'], ['D27.720.031.700.366', 'D27.888.723.366'], ['G02.300'], ['D27.720.031.700.491', 'D27.888.723.491'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D02.705.400.625.600', 'D02.705.539.345.600', 'D02.886.300.692.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Sotalol in the treatment of fetal tachyarrhythmia. | BACKGROUND: Fetal tachycardia is an uncommon condition that if sustained may lead to fetal death. There is no consensus regarding the optimum treatment. The aim of this study was to evaluate the safety and efficacy of sotalol in the treatment of fetal tachycardia.METHODS: This was a retrospective study of patients trea... | ['Anti-Arrhythmia Agents', 'Fetal Diseases', 'Humans', 'Retrospective Studies', 'Sotalol', 'Tachycardia'] | 16,910,155 | [['D27.505.954.411.097'], ['C13.703.277', 'C16.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ['D02.033.100.291.805', 'D02.092.063.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Neurophysiologic measurement of continuity in the sleep of fetuses during the last week of pregnancy and in newborns. | Our aim was to measure the correlation between fetal electrocardiographic (FECG) recordings of low-risk pregnancies and polysomnographic (PSG) study parameters in low-risk infants born at term as a measurement of perinatal sleep-development continuity. We designed a short, prospective, observational follow-up of physio... | ['Electrocardiography', 'Female', 'Fetus', 'Humans', 'Infant, Newborn', 'Male', 'Polysomnography', 'Sleep'] | 18,167,533 | [['E01.370.370.380.240', 'E01.370.405.240'], ['A16.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.370.520.625'], ['F02.830.855', 'G11.561.803']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The mutations in the fibronectin gene described in Japanese patients with systemic sclerosis are not present in Dutch patients. | Recently, a mutant fibronectin gene was identified in skin fibroblasts obtained from sclerotic lesions of 7 Japanese patients with systemic sclerosis (SSc). Two point mutations were found adjacent to the cell-attachment tetrapeptide DNA sequence in exon 7 of the fibronectin gene. In the present study, we investigated w... | ['Base Sequence', 'Exons', 'Fibronectins', 'Genes', 'Humans', 'Japan', 'Molecular Sequence Data', 'Mutation', 'Netherlands', 'Polymerase Chain Reaction', 'Scleroderma, Systemic'] | 2,012,628 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.360.340.024.340.137.232'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['G05.360.340.024.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['L01.453.245.667'], ['... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
AIDS awareness among rural Utah physicians. | Studies of physicians' attitudes and knowledge of the acquired immunodeficiency syndrome (AIDS) and the clinical precautions they take against exposure to the human immunodeficiency virus (HIV) have focused on urban physicians. To determine rural physicians' knowledge and attitudes about AIDS, a questionnaire was maile... | ['Acquired Immunodeficiency Syndrome', 'Attitude of Health Personnel', 'Clinical Competence', 'HIV Seropositivity', 'Humans', 'Physicians', 'Rural Population', 'Surveys and Questionnaires', 'Utah'] | 1,877,200 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['F01.100.050', 'N05.300.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.5... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Enrichment and release of uranium during weathering of sedimentary rocks in Wujiang catchments]. | Thirteen weathering profiles of typical rocks such as limestone, dolomitic limestone, dolomite, sillcalite, black shale and purple sandrock from Wujiang catchments were selected for discussing enrichment and release behavior of uranium (U) during rock weathering, and studying its impact on riverine U distribution in th... | ['China', 'Environmental Pollution', 'Fresh Water', 'Geography', 'Geologic Sediments', 'Rivers', 'Soil Pollutants, Radioactive', 'Uranium', 'Water Pollutants, Radioactive'] | 17,326,439 | [['Z01.252.474.164'], ['N06.850.460'], ['G16.500.275.280', 'N06.230.232'], ['H01.277.500'], ['G01.311.330', 'G16.500.320'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['D20.693.756', 'D27.888.284.756.674'], ['D01.268.271.100.950', 'D01.268.556.900', 'D01.496.749.305.100.950', 'D01.552.020.940', 'D01.552... | ['Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Genome-Wide CRISPR/Cas9 Screening for High-Throughput Functional Genomics in Human Cells. | It is highly desirable to identify gene's function in a high-throughput fashion, and the CRISPR/Cas9 system has been harnessed to meet such a need. Here, we describe a general method to generate genome-scale lentiviral single-guide RNA (sgRNA) library and conduct a pooled function-based screening in human cells. This p... | ['CRISPR-Cas Systems', 'Cell Line', 'Gene Library', 'Genome-Wide Association Study', 'Genomics', 'Humans'] | 28,808,970 | [['G05.308.203.374.394'], ['A11.251.210'], ['G05.360.325'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Activities of antimicrobial agents against intracellular pneumococci. | Pneumococci can enter and survive inside human lung alveolar carcinoma cells. We examined the activity of azithromycin, gentamicin, levofloxacin, moxifloxacin, penicillin G, rifampin, telithromycin, and trovafloxacin against pneumococci inside and outside cells. We found that moxifloxacin, trovafloxacin, and telithromy... | ['Anti-Bacterial Agents', 'Aza Compounds', 'Azithromycin', 'Fluoroquinolones', 'Gentamicins', 'Humans', 'Ketolides', 'Levofloxacin', 'Macrolides', 'Microbial Sensitivity Tests', 'Moxifloxacin', 'Naphthyridines', 'Ofloxacin', 'Penicillin G', 'Quinolines', 'Rifampin', 'Streptococcus pneumoniae', 'Tumor Cells, Cultured'] | 10,952,618 | [['D27.505.954.122.085'], ['D02.145'], ['D02.540.576.500.992.050'], ['D03.633.100.810.835.322'], ['D09.408.051.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.540.576.500.992.445'], ['D03.633.100.810.835.322.500.500'], ['D02.540.505', 'D02.540.576.500', 'D04.345.674.500'], ['E01.370.225.875.595', 'E05.200... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The prediction of outcome in somatised patients undergoing elective lumbar surgery. | We compared a group of 46 somatised patients with a control group of 41 non-somatised patients who had undergone elective surgery to the lumbar spine in an attempt to identify pre-operative factors which could predict the outcome. In a prospective single-centre study, the Distress and Risk Assessment method consisting ... | ['Adult', 'Aged', 'Attitude to Health', 'Case-Control Studies', 'Decompression, Surgical', 'Disability Evaluation', 'Diskectomy', 'Female', 'Humans', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Patient Acceptance of Health Care', 'Prognosis', 'Prospective Studies', 'Psychiatric Status Rating Scales', 'Psychometrics', '... | 19,336,814 | [['M01.060.116'], ['M01.060.116.100'], ['F01.100.150', 'N05.300.150'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E04.188'], ['E01.370.400'], ['E02.718.444', 'E04.188.350', 'E04.555.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['M01.060.116.630']... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Uranium in groundwater - A synopsis based on a large hydrogeochemical data set. | Most of the knowledge on the occurrence of Uranium (U) in groundwater comes from in-situ manipulation experiments in the field, computational modelling studies or from laboratory analyses where individual processes of U mobilization were studied in isolation. Because of Uranium's vital redox chemistry it interacts, oft... | ['Carbon', 'Carbonates', 'Groundwater', 'Iron', 'Manganese', 'Minerals', 'Nitrates', 'Oxidation-Reduction', 'Uranium', 'Water Pollutants, Radioactive'] | 29,127,832 | [['D01.268.150'], ['D01.045.125', 'D01.200.275.150', 'D01.248.497.158.165'], ['G01.311.355'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D01.268.556.484', 'D01.268.956.374', 'D01.552.544.484'], ['D01.578'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['G02.700', 'G03.295.531'], ['D01.268.27... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of the unloading conditions on capping and lamination: Study on a compaction simulator. | Capping and lamination are classical industrial issues that can be challenging during the scale up of solid dosage forms. Previous publications showed that changing the unloading conditions (triaxial decompression, loaded ejection) made it possible to mitigate capping. In the present study, a systematic study of the ef... | ['Powders', 'Pressure', 'Tablets', 'Technology, Pharmaceutical'] | 31,252,150 | [['D26.255.779'], ['G01.374.715'], ['D26.255.830'], ['E05.916', 'J01.897.836']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Tracking the Neurodevelopmental Correlates of Mental State Inference in Early Childhood. | Between ages 4 and 6, children become better at inferring what others are thinking and feeling. However, the neural correlates of these advances are understudied. The current study investigated the relation between performance on a face-based mental state inference task and white matter characteristics. Two tracts of i... | ['Anisotropy', 'Child', 'Child, Preschool', 'Diffusion Tensor Imaging', 'Emotions', 'Facial Expression', 'Female', 'Frontal Lobe', 'Humans', 'Male', 'Neural Pathways', 'Pattern Recognition, Visual', 'White Matter'] | 26,731,628 | [['G01.590.040', 'G02.050'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.350.578.750', 'E01.370.350.825.500.150.500', 'E01.370.376.537.500', 'E05.629.750'], ['F01.470'], ['E01.370.600.225', 'F01.145.209.530.385'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.612'], ['F... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Outbreak of Serratia marcescens Coproducing ArmA and CTX-M-15 Mediated High Levels of Resistance to Aminoglycoside and Extended-Spectrum Beta-Lactamases, Algeria. | Serratia marcescens is one of the most important pathogens responsible for nosocomial infections worldwide. Here, we have investigated the molecular support of antibiotic resistance and genetic relationships in a series of 54 S. marcescens clinical isolates collected from Eastern Algeria between December 2011 and July ... | ['Algeria', 'Aminoglycosides', 'Anti-Bacterial Agents', 'Conjugation, Genetic', 'Disease Outbreaks', 'Drug Resistance, Bacterial', 'Genes, Bacterial', 'Humans', 'Microbial Sensitivity Tests', 'Plasmids', 'RNA, Ribosomal, 16S', 'Serratia Infections', 'Serratia marcescens', 'beta-Lactamases'] | 25,884,511 | [['Z01.058.266.104'], ['D09.408.051'], ['D27.505.954.122.085'], ['G05.728.200'], ['N06.850.290'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E0... | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The changing profile of autopsied deaths in the United States, 1972-2007. | An autopsy, the medical examination of a deceased person, may confirm clinical findings, provide more complete information to describe cause of death, or uncover conditions not recognized clinically prior to death. Two types are performed in the United States: a) hospital or clinical autopsies, which family or physicia... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Autopsy', 'Cause of Death', 'Child', 'Child, Preschool', 'Humans', 'Infant', 'Middle Aged', 'United States', 'Young Adult'] | 22,142,988 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['M01.060.406'], ['... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Dietary supplementation with tBHQ, an Nrf2 stabilizer molecule, confers neuroprotection against apoptosis in amyloid â-injected rat. | Nuclear factor erythroid 2-related factor 2 (Nrf2) coordinates the up-regulation of cytoprotective genes via the antioxidant response element (ARE). There is significant evidence that oxidative stress is a critical event in the pathogenesis of AD. Considering the protective role of Nrf2 against oxidative injury, we stu... | ['Amyloid beta-Peptides', 'Animals', 'Apoptosis', 'Blotting, Western', 'Dietary Supplements', 'Hippocampus', 'Hydroquinones', 'Male', 'NF-E2-Related Factor 2', 'Neuroprotective Agents', 'Oxidative Stress', 'Rats', 'Rats, Wistar'] | 21,293,924 | [['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G07.203.300.456', 'J02.500.456'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D02.455.426.559.389... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A model of the deciliation process caused by Mycoplasma fermentans strain incognitus on respiratory epithelium. | The aim of this study was to investigate by light microscopy as well as by scanning and transmission electron microscopy the deciliation process which takes place on the respiratory epithelium of tracheal explants after experimental infection with Mycoplasma fermentans strain incognitus. Time-point photography allowed ... | ['Animals', 'Cilia', 'Epithelial Cells', 'Microscopy, Electron, Scanning', 'Microscopy, Electron, Transmission', 'Models, Biological', 'Mycoplasma Infections', 'Mycoplasma fermentans', 'Organ Culture Techniques', 'Rats', 'Respiratory Mucosa'] | 16,898,668 | [['B01.050'], ['A11.284.180.165'], ['A11.436'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['E05.599.395'], ['C01.150.252.400.610.610'], ['B03.440.860.580.553.553.315'], ['E05.481.500.484'], ['B01.050.150.900.649.313.992.635.505.700'], ['A04.760', 'A10.615.550.760']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Urinary nitric oxide levels are increased and correlated with plasma concentrations in patients with Beh?et's disease: is it a new urinary activity marker? | Nitric oxide (NO) is a free radical and serves many functions within the kidney. Excess NO causes glomerular injury. Beh?et's disease (BD) is a systemic immunoinflammatory vasculitis, affecting every organ in the body including the kidneys (subclinic glomerulonephritis). We investigated the role of urinary total nitrit... | ['Adult', 'Behcet Syndrome', 'Biomarkers', 'Blood Urea Nitrogen', 'Case-Control Studies', 'Creatinine', 'Disease Progression', 'Female', 'Glomerular Filtration Rate', 'Humans', 'Kidney', 'Male', 'Middle Aged', 'Nitric Oxide', 'Nitrites', 'Predictive Value of Tests', 'Up-Regulation'] | 15,012,709 | [['M01.060.116'], ['C07.465.075', 'C11.941.879.780.880.200', 'C14.907.940.100', 'C16.320.382.250', 'C17.800.827.368.250', 'C17.800.862.150'], ['D23.101'], ['E01.370.225.124.100.115', 'E01.370.390.400.100', 'E05.200.124.100.115'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D03.383.1... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Paediatric cycloplegia: a new approach. | BACKGROUND: Cycloplegia is a traumatic experience for most children, as guttae cyclopentolate stings on instillation into the conjunctival sac. This may result in inadequate cycloplegia, difficulty in further examination and a child who is scared of both the doctor and the ophthalmology department. Guttae proxymetacain... | ['Anesthetics, Local', 'Attitude to Health', 'Child', 'Child, Preschool', 'Cyclopentolate', 'Female', 'Humans', 'Infant', 'Male', 'Mydriatics', 'Ophthalmic Solutions', 'Propoxycaine', 'Prospective Studies', 'Retrospective Studies', 'Stress, Psychological'] | 9,537,142 | [['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['F01.100.150', 'N05.300.150'], ['M01.060.406'], ['M01.060.406.448'], ['D02.241.223.601.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D27.505.696.663.050.500'], ['D26.776.708.645', 'D27.505.954.578.645',... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Azacitidine-Induced Pericarditis: A Case Series. | STUDY OBJECTIVE: To describe three cases of pericarditis probably related to azacitidine administration in a span of 3 years at our center.DESIGN: Case series.SETTING: Comprehensive cancer center within a large, academic medical center.PATIENTS: Three patients with high-grade myelodysplastic syndrome or acute myeloid l... | ['Aged', 'Antimetabolites, Antineoplastic', 'Azacitidine', 'Chest Pain', 'Combined Modality Therapy', 'DNA Modification Methylases', 'Diagnosis, Differential', 'Drug Monitoring', 'Enzyme Inhibitors', 'Female', 'Glucocorticoids', 'Humans', 'Leukemia, Myeloid, Acute', 'Male', 'Methylprednisolone', 'Middle Aged', 'Myelody... | 26,940,554 | [['M01.060.116.100'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['D02.145.150', 'D03.383.742.680.245.217', 'D13.570.685.245.217', 'D13.570.800.286.300'], ['C23.888.592.612.233'], ['E02.186'], ['D08.811.150.240', 'D08.811.913.555.500.350'], ['E01.171'], ['E01.370.520.200'], ['D27.505.519.389... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Incorporation of Farnesol Significantly Increases the Efficacy of Liposomal Ciprofloxacin against Pseudomonas aeruginosa Biofilms in Vitro. | The challenge of eliminating Pseudomonas aeruginosa infections, such as in cystic fibrosis lungs, remains unchanged due to the rapid development of antibiotic resistance. Poor drug penetration into dense P. aeruginosa biofilms plays a vital role in ineffective clearance of the infection. Thus, the current antibiotic th... | ['Anti-Bacterial Agents', 'Biofilms', 'Ciprofloxacin', 'Farnesol', 'Liposomes', 'Microbial Sensitivity Tests', 'Microscopy, Confocal', 'Microscopy, Electron, Transmission', 'Pseudomonas aeruginosa'] | 27,383,205 | [['D27.505.954.122.085'], ['A20.593', 'G06.120'], ['D03.633.100.810.835.322.186'], ['D02.033.415.400', 'D02.455.849.765.424', 'D10.289.400'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['E01.370.350.515.395', 'E05.595.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Structures of the subgel phases of n-saturated diacyl phosphatidylcholine bilayers: FTIR spectroscopic studies of 13C = O and 2H labeled lipids. | The subgel phases of unlabeled, specifically chain perdeuterated and specifically 13C = O labeled representative samples of the n-saturated diacylphosphatidylcholines were studied by Fourier-transform infrared spectroscopy. Our results indicate that the spectroscopic properties exhibited by the subgel phases of the lon... | ['Carbon Isotopes', 'Deuterium', 'Fourier Analysis', 'Gels', 'Lipid Bilayers', 'Models, Structural', 'Molecular Conformation', 'Phosphatidylcholines', 'Spectrophotometry, Infrared', 'Structure-Activity Relationship', 'X-Ray Diffraction'] | 1,540,700 | [['D01.268.150.075', 'D01.496.123'], ['D01.268.406.500', 'D01.362.340.500', 'D01.496.289'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['D20.280.320', 'D26.255.165.320'], ['D10.570.510', 'J01.637.087.500.510'], ['J01.897.280.500.545', 'L01.178.820.090.545'], ['G02.111.570.820'], ['D10.570.755.375.760.400.800'], ['E05.1... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Biocatalytic oxidation by chloroperoxidase from Caldariomyces fumago in polymersome nanoreactors. | The encapsulation of chloroperoxidase from Caldariomyces fumago (CPO) in block copolymer polymersomes is reported. Fluorescence and electron microscopy show that when the encapsulating conditions favour self-assembly of the block copolymer, the enzyme is incorporated with concentrations that are 50 times higher than th... | ['Ascomycota', 'Biocatalysis', 'Chloride Peroxidase', 'Filtration', 'Kinetics', 'Microscopy, Confocal', 'Models, Chemical', 'Nanostructures', 'Oxidation-Reduction', 'Polymers', 'Pyrogallol', 'Spectrophotometry, Ultraviolet', 'Sulfides', 'Sulfur', 'Time Factors'] | 19,865,695 | [['B01.300.107'], ['G02.111.086', 'G02.130.500', 'G03.105'], ['D08.811.682.732.360'], ['E05.196.454', 'G01.280', 'G02.263'], ['G01.374.661', 'G02.111.490'], ['E01.370.350.515.395', 'E05.595.395'], ['E05.599.495'], ['J01.637.512'], ['G02.700', 'G03.295.531'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D02.455.426.559.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Saponins and other constituents from the leaves of Aralia elata. | A new triterpenoid saponin, together with five known saponins, were isolated from the nonpolar n-hexane fraction of the leaves of Aralia elata. The structure of the new saponin, durupcoside C, was elucidated as hederagenin 3-O-beta-D-glucopyranosyl(1-->3)-beta-D-glucopyranosyl(1-->3)-alpha-L-arabinopyranoside on the ba... | ['Aralia', 'Plant Extracts', 'Plant Leaves', 'Saponins'] | 15,930,787 | [['B01.650.940.800.575.912.250.087.249'], ['D20.215.784.500', 'D26.667'], ['A18.024.812'], ['D09.408.782']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oncostatin m is produced in adipose tissue and is regulated in conditions of obesity and type 2 diabetes. | CONTEXT: Adipose tissue is a highly active endocrine organ that secretes many factors that affect other tissues and whole-body metabolism. Adipocytes are responsive to several glycoprotein 130 (gp130) cytokines, some of which have been targeted as potential antiobesity therapeutics.OBJECTIVE: Oncostatin M (OSM) is a gp... | ['3T3-L1 Cells', 'Adipose Tissue', 'Animals', 'Diabetes Mellitus, Type 2', 'Gene Expression Regulation', 'Humans', 'Male', 'Mice', 'Obesity', 'Oncostatin M', 'Receptors, Oncostatin M'] | 24,297,795 | [['A11.251.210.100.775.800', 'A11.329.228.100.775.800'], ['A10.165.114'], ['B01.050'], ['C18.452.394.750.149', 'C19.246.300'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bacterial community and arsenic functional genes diversity in arsenic contaminated soils from different geographic locations. | To understand how soil microbial communities and arsenic (As) functional genes respond to soil arsenic (As) contamination, five soils contaminated with As at different levels were collected from diverse geographic locations, incubated for 54 days under flooded conditions, and examined by both MiSeq sequencing of 16S rR... | ['Arsenic', 'Bacteria', 'Genes, Bacterial', 'Geography', 'RNA, Ribosomal, 16S', 'Soil Microbiology', 'Soil Pollutants'] | 28,475,654 | [['D01.268.513.249'], ['B03'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['H01.277.500'], ['D13.444.735.686.670'], ['H01.158.273.540.274.555', 'N06.850.425.300'], ['D27.888.284.756']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Spontaneous pneumomediastinum, emphysema, and pulmonary bullae associated with refractory Mycoplasma pneumoniae pneumonia in a child. | We report a 21-month-old child with spontaneous pneumomediastinum (PM), emphysema, and pulmonary bullae caused by Mycoplasma pneumonia (M. pneumoniae) pneumonia. The patient presented with stubborn dyspnea and wheezing although received integrated treatment, including anti-infection, anti-inflammation, and intravenous ... | ['Blister', 'Humans', 'Infant', 'Male', 'Mediastinal Emphysema', 'Pneumonia, Mycoplasma', 'Pulmonary Emphysema', 'Respiratory Sounds'] | 28,752,681 | [['C17.800.865.187', 'C23.300.122'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C08.846.187.290', 'C23.550.325.250'], ['C01.150.252.400.610.610.760', 'C01.150.252.620.500', 'C01.748.610.540.545', 'C08.381.677.540.500', 'C08.730.610.540.545'], ['C08.381.495.389.750'], ['C23.888.852.779', 'E01.37... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Brachioplasty outcomes: a review of a multipractice cohort. | BACKGROUND: Upper arm deformities secondary to massive weight loss or senile elastosis have led to an increased demand for aesthetic contouring procedures such as brachioplasty.METHODS: The records of all patients who underwent a brachioplasty procedure from a multipractice medical center were reviewed. Outcomes measur... | ['Adult', 'Aged', 'Arm', 'Cohort Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Reconstructive Surgical Procedures', 'Treatment Outcome'] | 23,542,260 | [['M01.060.116'], ['M01.060.116.100'], ['A01.378.800.075'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.680'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Knee arthroplasty in octogenarians: results at 10 years. | The purpose of this study was to assess the long-term results of total knee arthroplasty (TKA) in octogenarians. Between 1976 and 1989, 1 surgeon at our institution performed 110 TKAs in 90 patients who were 80 years of age or older. No patients were lost to follow-up monitoring; all living patients underwent a minimum... | ['Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Knee', 'Female', 'Humans', 'Knee Joint', 'Knee Prosthesis', 'Male', 'Osteoarthritis, Knee', 'Pain Measurement', 'Postoperative Complications', 'Recovery of Function', 'Survival Analysis'] | 12,728,420 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['E07.695.400.410'], ['C05.550.114.606.500', 'C05.799.613.500'], ['E01.370.600.550.324'], ['C23.550.767'], ['G16.757'], ['E05.318.740.99... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Obesity and its association with sociodemographic factors, health behaviours and health status among Aboriginal and non-Aboriginal adults in New South Wales, Australia. | BACKGROUND: High body mass index (BMI) is the second leading contributor to Australia's burden of disease and is particularly prevalent among Aboriginal peoples. This paper aims to provide insight into factors relating to obesity among Aboriginal adults and Aboriginal-non-Aboriginal differences.METHODS: Cross-sectional... | ['Adult', 'Body Mass Index', 'Cross-Sectional Studies', 'Female', 'Health Behavior', 'Health Status', 'Humans', 'Male', 'Middle Aged', 'Motor Activity', 'New South Wales', 'Obesity', 'Oceanic Ancestry Group', 'Prevalence', 'Socioeconomic Factors'] | 29,514,925 | [['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.488'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.06... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Adrenergic regulation of phosphorolysis and hydrolysis of glycogen in smooth muscle of rabbit stomach in situ. | In smooth muscle of rabbit stomachs, activities of hydrolytic and phosphorolytic enzymes of glycogen degradation under the influence of agents stimulating and blocking adrenergic alpha and beta-receptors were studied. The results indicate that beta-adrenergic receptor in smooth muscle activated not only phosphorolytic,... | ['Acetylcholine', 'Amylases', 'Animals', 'Bethanechol Compounds', 'Cyclic AMP', 'Glycogen', 'Hexosephosphates', 'Male', 'Muscle, Smooth', 'Rabbits', 'Sotalol', 'Sympathomimetics'] | 206,225 | [['D02.092.211.111'], ['D08.811.277.450.066'], ['B01.050'], ['D02.092.877.883.088', 'D02.241.081.251.133', 'D02.675.276.148'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D05.750.078.562.388', 'D09.698.365.388'], ['D09.894.417'], ['A02.633.570', 'A10.690.467'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Olfactory and gustatory sensitivity in adults with attention-deficit/hyperactivity disorder. | Recently, research on olfactory functions in attention-deficit/hyperactivity disorder (ADHD) has become prominent, whereas gustation has never been investigated. Increased odor sensitivity was found in medication-na?ve children with ADHD, but not in adult ADHD, which might be due to a dopaminergic dysregulation presume... | ['Adult', 'Attention Deficit Disorder with Hyperactivity', 'Bulimia Nervosa', 'Case-Control Studies', 'Female', 'Humans', 'Neuropsychological Tests', 'Olfactory Perception', 'Taste', 'Taste Perception'] | 21,432,618 | [['M01.060.116'], ['F03.625.094.150'], ['F03.400.250'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513'], ['F02.463.593.485'], ['F02.830.816.724', 'G11.561.790.724'], ['F02.463.593.817']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Incidence of heart disease in 35,000 women treated with radiotherapy for breast cancer in Denmark and Sweden. | PURPOSE: To study incidence of radiation-related heart disease in a large population of breast cancer patients followed for up to 30 years.MATERIAL AND METHODS: 72,134 women diagnosed with breast cancer in Denmark or Sweden during 1976-2006 and followed prospectively. Radiation-related risk was studied by comparing wom... | ['Adult', 'Aged', 'Breast Neoplasms', 'Denmark', 'Female', 'Heart Diseases', 'Humans', 'Incidence', 'Middle Aged', 'Radiation Injuries', 'Radiotherapy', 'Sweden'] | 21,752,480 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['Z01.542.816.124'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.116.630'], ['C26.733', 'G01.750.748.50... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Interspecific pheromone cross-attraction among soybean bugs (Heteroptera): does Piezodorus hybneri (Pentatomidae) utilize the pheromone of Riptortus clavatus (Alydidae) as a kairomone? | The chemical and ecological function of cross-attraction of Piezodorus hybneri (Pentatomidae) to the Riptortus clavatus (Alydidae) pheromone (a mixture of three components) was studied. In a field attraction test using traps with synthetic pheromone components, P. hybneri was attracted to (E)-2-hexenyl (E)-2-hexenoate,... | ['Animals', 'Caproates', 'Ecology', 'Heteroptera', 'Pheromones', 'Soybeans', 'Species Specificity', 'Tissue Extracts'] | 16,705,488 | [['B01.050'], ['D02.241.081.193', 'D10.251.400.326'], ['H01.158.273.248', 'H01.277.249'], ['B01.050.500.131.617.412.420'], ['D23.641'], ['B01.650.940.800.575.912.250.401.750'], ['G16.824'], ['D20.777']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
HLA-DR antigens in juvenile chronic arthritis. | Twenty-five patients with juvenile chronic arthritis (JCA) were typed for HLA-A,-G,-C and -DR antigens to establish significant differences between normal controls and patients with adult rheumatoid arthritis (RA). HLA-DR antigens were correlated with subgroups of disease, and with several clinical features and immunol... | ['Arthritis', 'Arthritis, Juvenile', 'Child', 'Chronic Disease', 'Female', 'HLA Antigens', 'HLA-A Antigens', 'HLA-B Antigens', 'HLA-C Antigens', 'HLA-DR Antigens', 'Histocompatibility Antigens Class II', 'Humans', 'Male'] | 6,956,735 | [['C05.550.114'], ['C05.550.114.122', 'C05.799.056', 'C17.300.775.049', 'C20.111.198'], ['M01.060.406'], ['C23.550.291.500'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['D12.776.395.550.489.400', 'D12.776.543.550.439.400', 'D23.050.301.500.100.400', 'D23.050.301.500.450.370', 'D23.050.705.552.100.400', 'D23.050.7... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Biological functional annotation of retinoic acid alpha and beta in mouse liver based on genome-wide binding. | Retinoic acid (RA) has diverse biological effects. The liver stores vitamin A, generates RA, and expresses receptors for RA. The current study examines the hepatic binding profile of two RA receptor isoforms, RARA (RARá) and RARB (RARâ), in response to RA treatment in mouse livers. Our data uncovered 35,521, and 14,968... | ['Amino Acid Motifs', 'Animals', 'Binding Sites', 'Chromatin Immunoprecipitation', 'Gene Expression Regulation', 'Genome-Wide Association Study', 'Liver', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Principal Component Analysis', 'Promoter Regions, Genetic', 'Protein Binding', 'Receptors, Retinoic Acid', 'Retinoic Acid Rece... | 24,833,708 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['B01.050'], ['G02.111.570.120'], ['E05.393.170', 'E05.478.605.160'], ['G05.308'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['A03.620'], ['B01.050.15... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A Survey of Knowledge and Beliefs regarding Autism in Speech-Language Pathologists in India. | BACKGROUND: Speech-language pathologists (SLPs) are significant team members in the identification, assessment, and rehabilitation of children with autism. With a recent upsurge in the number of children with autism, there arises a need to examine SLPs knowledge and skills in identification and intervention of children... | ['Attitude of Health Personnel', 'Autistic Disorder', 'Clinical Competence', 'Cross-Sectional Studies', 'Culture', 'Female', 'Humans', 'India', 'Male', 'Speech-Language Pathology', 'Surveys and Questionnaires'] | 30,231,250 | [['F01.100.050', 'N05.300.100'], ['F03.625.164.113.500'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.076.201.450', 'I01.880.853.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['H02.010.750'], ['E05... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Diffuse large B-cell lymphoma with a novel translocation involving BCL6. | Translocation of the BCL6 gene is one of the most common chromosomal changes seen in diffuse large B-cell lymphoma, primarily affecting the 5' regulatory region which is usually replaced with the sequences of the translocation partner. This translocation involves both immunoglobulin and nonimmunoglobulin gene partners,... | ['Chromosomes, Human, Pair 11', 'Cytogenetics', 'DNA-Binding Proteins', 'Humans', 'Immunohistochemistry', 'Immunophenotyping', 'In Situ Hybridization, Fluorescence', 'Karyotyping', 'Lymph Nodes', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Proto-Oncogene Proteins c-bcl-6', 'Translocation, Genetic'] | 17,889,713 | [['A11.284.187.520.300.325.355', 'G05.360.162.520.300.325.355'], ['H01.158.273.343.180'], ['D12.776.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512'... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Spirituality in occupational therapy: do we practice what we teach? | This mixed-method study examined the responses of 97 occupational therapists on the subject of spirituality in occupational therapy practice. The inclusion of spirituality into the Occupational Therapy Practice Framework (2008) implies that clinicians address spirituality as a component of client-centered practice. Thi... | ['Attitude of Health Personnel', 'Holistic Health', 'Humans', 'Occupational Therapy', 'Professional Role', 'Professional-Patient Relations', 'Spirituality', 'Surveys and Questionnaires'] | 22,395,753 | [['F01.100.050', 'N05.300.100'], ['E02.190.321', 'K01.752.667.710', 'N01.400.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.169.063.500.489', 'E02.831.489', 'H02.010.500'], ['F01.829.316.616.625'], ['F01.829.401.650', 'N05.300.660'], ['F02.880.705', 'K01.844.664.500'], ['E05.318.308.980', 'N05.715.36... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Peculiarities of myocardial infarction at young age in Southern Croatia. | The aim of this study was to assess whether acute myocardial infarction (AMI) in younger patients (< 45 years) differs from that in the older individuals (> 45 years). We have studied the records of all patients admitted to the Department of Medicine, Clinical Hospital of Split, Croatia, because of AMI from January 1st... | ['Adult', 'Age Distribution', 'Croatia', 'Female', 'Hospital Mortality', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Retrospective Studies', 'Risk Factors', 'Sex Distribution'] | 8,640,853 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['Z01.542.248.295'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C2... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids. | BACKGROUND: Insulin resistance and hyperinsulinemia are features of obesity, non-insulin-dependent diabetes mellitus, and other disorders. Skeletal muscle is a major site of insulin action, and insulin sensitivity may be related to the fatty-acid composition of the phospholipids within the muscle membranes involved in ... | ['Aged', 'Coronary Disease', 'Fatty Acids', 'Female', 'Humans', 'Insulin', 'Insulin Resistance', 'Male', 'Middle Aged', 'Muscles', 'Phospholipids'] | 8,418,404 | [['M01.060.116.100'], ['C14.280.647.250', 'C14.907.585.250'], ['D10.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['M01.060.116.630'], ['A02.633', 'A10.690'], ['D10.570.755']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Differential but Complementary HIF1á and HIF2á Transcriptional Regulation. | Effective vascular regeneration could provide therapeutic benefit for multiple pathologies, especially in chronic peripheral artery disease (PAD) and myocardial ischemia. The hypoxia inducible factors (HIFs) mediate the cellular transcriptional response to hypoxia and regulate multiple processes that are required for a... | ['Basic Helix-Loop-Helix Transcription Factors', 'Cell Line', 'Extracellular Matrix', 'Gene Expression Regulation', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'Hypoxia', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Neovascularization, Physiologic', 'Transcription Factors', 'Transcription, Genetic'] | 29,843,956 | [['D12.776.260.103', 'D12.776.930.125'], ['A11.251.210'], ['A11.284.295.310'], ['G05.308'], ['A11.436.275.682'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.079'], ['D12.776.260.103.625.750', 'D12.776.930.125.625.750'], ['G09.330.630'], ['D12.776.930'], ['G02.111.873', 'G05.297.700']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cerebral arteries: fully automated segmentation from CT angiography--a feasibility study. | The purpose of this study was to retrospectively assess the feasibility of a fully automated image postprocessing tool for the segmentation of the arterial cerebrovasculature from computed tomographic (CT) angiography in 27 patients (nine men, 18 women; mean age, 55 years; age range, 33-76 years) with subarachnoid hemo... | ['Adult', 'Aged', 'Angiography, Digital Subtraction', 'Automation', 'Cerebral Angiography', 'Cerebral Arteries', 'Contrast Media', 'Feasibility Studies', 'Female', 'Humans', 'Iohexol', 'Male', 'Middle Aged', 'Radiographic Image Interpretation, Computer-Assisted', 'Retrospective Studies', 'Subarachnoid Hemorrhage', 'Tom... | 18,487,538 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['J01.897.104'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Gaucher disease mouse models: point mutations at the acid beta-glucosidase locus combined with low-level prosaposin expression lead to disease variants. | Gaucher disease is a common lysosomal storage disease caused by a defect of acid beta-glucosidase (GCase). The optimal in vitro hydrolase activity of GCase requires saposin C, an activator protein that derives from a precursor, prosaposin. To develop additional models of Gaucher disease and to test in vivo effects of s... | ['Animals', 'Brain', 'Crosses, Genetic', 'Disease Models, Animal', 'Gaucher Disease', 'Glucosylceramidase', 'Glucosylceramides', 'Liver', 'Lung', 'Mice', 'Phenotype', 'Point Mutation', 'Saposins', 'Spleen', 'Thymus Gland', 'Transgenes'] | 16,061,944 | [['B01.050'], ['A08.186.211'], ['E05.393.281'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.228.140.163.100.435.825.400', 'C16.320.565.189.435.825.400', 'C16.320.565.398.641.803.441', 'C16.320.565.595.554.825.400', 'C18.452.132.100.435.825.400', 'C18.452.584.687.803.441', 'C18.452.648.189.435.825.400', 'C18.45... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Myxomas of the head and neck. | Myxomas are benign mesenchymal tumors that occur rarely in the head and neck. When they do occur, they are prevalent in the jaws and occur less frequently in the subcutaneous tissues. We report ten new cases and review the clinical, structural, and behavioral characteristics of myxomas arising in various head and neck ... | ['Adolescent', 'Adult', 'Aged', 'Diagnosis, Differential', 'Fibrosarcoma', 'Head and Neck Neoplasms', 'Humans', 'Liposarcoma', 'Male', 'Myxoma', 'Recurrence'] | 1,267,724 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.171'], ['C04.557.450.565.590.350', 'C04.557.450.795.350'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.550.420', 'C04.557.450.795.465'], ['C04.557.450.565.550'], ['C23.550.291.937']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Final results of ERASME-4: a randomized trial of first-line docetaxel plus either capecitabine or epirubicin for metastatic breast cancer. | OBJECTIVE: To assess the efficacy of capecitabine plus docetaxel (XT) versus epirubicin plus docetaxel (ET) as first-line therapy for metastatic breast cancer (MBC).PATIENTS AND METHODS: Patients with no prior chemotherapy for MBC were randomized to 3-weekly cycles of either XT (capecitabine 1,000 mg/m(2) twice daily, ... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Breast Neoplasms', 'Capecitabine', 'Deoxycytidine', 'Disease-Free Survival', 'Docetaxel', 'Early Termination of Clinical Trials', 'Epirubicin', 'Female', 'Fluorouracil', 'Humans', 'Intention to Treat Analysis', 'Kaplan-Meier Estimate', 'Middle Aged', ... | 21,734,418 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.180', 'C17.800.090.500'], ['D03.383.742.680.245.500.425', 'D03.383.742.698.875.404.425', 'D13.570.230.329.313', 'D13.570.685.245.500.425'], ['D03.383.742.680.245.500', 'D13.570.230.329', 'D13.570.685.245.500'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Isolation of halophilic vibrios from humans and the environment]. | Both biotypes of halophilous vibrios, V. parahaemolyticus and V. alginolyticus, have been found to cause intestinal diseases among the inhabitants of the littoral localities of the Crimea. These diseases mostly assume the form of acute gastroenteritis and alimentary toxic infections. Most frequently people contact infe... | ['Adult', 'Agglutination Tests', 'Animals', 'Bivalvia', 'Decapoda', 'Dysentery', 'Enteritis', 'Fishes', 'Foodborne Diseases', 'Gastroenteritis', 'Gastrointestinal Diseases', 'Humans', 'Ukraine', 'Vibrio', 'Vibrio Infections', 'Water Microbiology'] | 7,192,466 | [['M01.060.116'], ['E01.370.225.812.735.050', 'E05.200.812.735.050', 'E05.478.594.760.050'], ['B01.050'], ['B01.050.500.644.080'], ['B01.050.500.131.365.190'], ['C06.405.205.331', 'C06.405.469.300'], ['C06.405.205.462', 'C06.405.469.326'], ['B01.050.150.900.493'], ['C25.723.415'], ['C06.405.205'], ['C06.405'], ['B01.05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Intimate Relationships and Sexual Behavior in Young Women withDepression. | PURPOSE: To better understand links between depressive symptoms and high-risk sexual behavior in young women.METHODS: We conducted semistructured interviews with young women from three primary care clinics who reported clinically significant depressive symptoms, had penile-vaginal sexual intercourse within the past 6 m... | ['Adolescent', 'Adult', 'Depression', 'Female', 'Humans', 'Interpersonal Relations', 'Risk-Taking', 'Sexual Behavior', 'Unsafe Sex', 'Young Adult'] | 30,120,062 | [['M01.060.057'], ['M01.060.116'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F01.145.722'], ['F01.145.802'], ['F01.145.802.987'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical and cytogenetic study of a non mosaic 46, X, isodicentric Yq in an Egyptian patient with Turner syndrome. | UNLABELLED: We report on a female with Turner syndrome phenotype and an isodicentric Y chromosome 46, X, idicYq a combination which has to the best of our knowledge not been reported before.OBJECTIVE: To delineate the phenotypic spectrum (clinical and gonadal features) for a female patient with 46, X, + marker karyotyp... | ['Child, Preschool', 'Chromosomes, Human, X', 'Chromosomes, Human, Y', 'Cytogenetic Analysis', 'Egypt', 'Female', 'Genetic Markers', 'Humans', 'In Situ Hybridization, Fluorescence', 'Karyotyping', 'Turner Syndrome'] | 23,610,863 | [['M01.060.406.448'], ['A11.284.187.520.300.325.680', 'A11.284.187.865.982.500', 'G05.360.162.520.300.325.680', 'G05.360.162.865.982.500'], ['A11.284.187.520.300.505.757', 'A11.284.187.865.983.500', 'G05.360.162.520.300.505.757', 'G05.360.162.865.983.500'], ['E01.370.225.500.385', 'E05.200.500.385', 'E05.242.385', 'E05... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Interchangeability between Pentacam and IOLMaster in phakic intraocular lens calculation. | PURPOSE: To evaluate the agreement and interchangeability between IOLMaster and Pentacam in phakic intraocular lens (IOL) calculations.METHODS: This was a prospective study involving measurement of the anterior segment parameters anterior chamber depth (ACD), white to white (WTW) line, and average anterior corneal curv... | ['Adult', 'Anterior Chamber', 'Axial Length, Eye', 'Cornea', 'Corneal Pachymetry', 'Corneal Topography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Optics and Photonics', 'Phakic Intraocular Lenses', 'Photography', 'Prospective Studies', 'Young Adult'] | 25,363,849 | [['M01.060.116'], ['A09.371.060.067'], ['A09.371.199', 'E01.370.600.115.100.660.500'], ['A09.371.060.217'], ['E01.370.380.112'], ['E01.370.380.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H01.671.617', 'J01.293.688'], ['E07.632.500.460.500'], ['E01.370.350.600', 'E05.712'], ['E05.318.3... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
In vitro differentiation of human adipose tissue-derived stem cells into islet-like clusters promoted by islet neogenesis-associated protein pentadecapeptide. | Human adipose tissue-derived stem cells (hASCs) are considered an ideal tool for the supply of insulin-producing cells to treat diabetes mellitus, with high differentiation efficiency. Islet neogenesis-associated protein (INGAP) is an initiator of islet neogenesis, and the peptide sequence comprising amino acids 104-11... | ['Adipose Tissue', 'Animals', 'Cell Differentiation', 'Diabetes Mellitus, Experimental', 'In Vitro Techniques', 'Islets of Langerhans', 'Male', 'Pancreatitis-Associated Proteins', 'Rats', 'Rats, Sprague-Dawley', 'Stem Cells'] | 25,471,531 | [['A10.165.114'], ['B01.050'], ['G04.152'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['E05.481'], ['A03.734.414', 'A06.300.414'], ['D12.776.503.280.578', 'D23.050.285.733', 'D23.101.140.780'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['A11.872']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of Puralpha with RNAs homologous to 7 SL determines its binding ability to the myelin basic protein promoter DNA sequence. | Cell type and developmental stage expression of the myelin basic protein (MBP) gene in mouse brain is regulated at the transcriptional level. Earlier studies from our laboratory have led to the identification of a DNA binding protein from mouse brain, named Puralpha, which interacts with the MB1 regulatory motif of the... | ['Animals', 'Base Sequence', 'Blotting, Northern', 'Brain', 'Cyclic AMP Response Element-Binding Protein', 'DNA', 'DNA-Binding Proteins', 'Gene Expression Regulation, Developmental', 'Mice', 'Molecular Sequence Data', 'Myelin Basic Protein', 'Nerve Tissue Proteins', 'Promoter Regions, Genetic', 'Protein Binding', 'RNA'... | 9,712,838 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['A08.186.211'], ['D12.776.260.108.184', 'D12.776.930.127.184'], ['D13.444.308'], ['D12.776.260'], ['G05.308.310'], ['B01.050.150.900.649.313.992.635.505.500'], ['L01.453.245.667'], ['D12.776.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Increase in caudate nuclei volumes of first-episode schizophrenic patients taking antipsychotic drugs. | OBJECTIVE: This study examined the pathomorphology of the caudate nuclei in first-episode schizophrenic patients with minimal previous neuroleptic exposure.METHOD: Magnetic resonance imaging (MRI) of the brain was used to examine longitudinally the caudate pathomorphology in 29 first-episode schizophrenic patients and ... | ['Adult', 'Age Factors', 'Antipsychotic Agents', 'Caudate Nucleus', 'Cerebral Cortex', 'Cerebral Ventricles', 'Dopamine', 'Dose-Response Relationship, Drug', 'Female', 'Follow-Up Studies', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Neuronal Plasticity', 'Prospective Studies', 'Psychiatric Status Rating Scales', '... | 7,916,539 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['A08.186.211.200.885.287.249.487.550.184'], ['A08.186.211.200.885.287.500'], ['A08.186.211.140'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Structural changes in RepA, a plasmid replication initiator, upon binding to origin DNA. | RepA protein is the DNA replication initiator of the Pseudomonas plasmid pPS10. RepA dimers bind to an inversely repeated operator sequence in repA promoter, thus repressing its own synthesis, whereas monomers bind to four directly repeated sequences (iterons) to initiate DNA replication. We had proposed previously tha... | ['Amino Acid Motifs', 'Chromatography, Gel', 'Cloning, Molecular', 'DNA', 'DNA Helicases', 'DNA-Binding Proteins', 'Dimerization', 'Dose-Response Relationship, Drug', 'Histidine', 'Kinetics', 'Leucine', 'Models, Molecular', 'Mutagenesis, Site-Directed', 'Mutation', 'Plasmids', 'Protein Binding', 'Protein Conformation',... | 12,637,554 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['E05.196.181.400.250'], ['E05.393.220'], ['D13.444.308'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['D12.776.260'], ['G02.206', 'G03.230'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.125.072.329', 'D12.125.142.308'], ['G01.374.661', 'G02.111.49... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Intra-axial pseudotumors in the central nervous system: clinicopathological analysis. | Intra-axial pseudotumors in the central nervous system often mimic malignant brain tumors and cause difficulty in diagnosis and treatment. The present study investigates their radiologic and histological features to elucidate diagnostic clues. Six cases were included in the study, one man and five women, ranging in age... | ['Adult', 'Aged', 'Aged, 80 and over', 'Brain Abscess', 'Brain Neoplasms', 'Cell Count', 'Central Nervous System Neoplasms', 'Cerebral Angiography', 'Coloring Agents', 'Demyelinating Diseases', 'Female', 'Gliosis', 'Histiocytosis, Non-Langerhans-Cell', 'Humans', 'Image Processing, Computer-Assisted', 'Immunohistochemis... | 21,046,308 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.207.090', 'C01.830.025.160', 'C10.228.140.116', 'C10.228.228.090'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['C04.588.614.250', 'C10.551.240'], ['E01.370.350... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
Leptomeningeal spread of intramedullary spinal cord tumors. Report of three cases. | Three patients with intramedullary spinal cord tumors and secondary leptomeningeal spread of their tumors are presented. Two patients had astrocytomas and one had a ganglioglioma. Two tumors were located in the cervical spinal cord and one within the thoracic spinal cord. Review of the past and recent literature shows ... | ['Adolescent', 'Astrocytoma', 'Child, Preschool', 'Glioma', 'Humans', 'Male', 'Meningeal Neoplasms', 'Spinal Cord Neoplasms'] | 3,392,575 | [['M01.060.057'], ['C04.557.465.625.600.380.080', 'C04.557.470.670.380.080', 'C04.557.580.625.600.380.080'], ['M01.060.406.448'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.614.250.580', 'C10.551.240.500'], ['C04.588.614.250.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
H19 gene overexpression in atypical multidrug-resistant cells associated with expression of a 95-kilodalton membrane glycoprotein. | The multidrug resistance phenotype of human breast carcinoma MCF-7/AdrVp cells is characterized by overexpression of a 95-kilodalton membrane glycoprotein (p95), accompanied by a marked reduction in intracellular anthracycline accumulation, without overexpression of P-glycoprotein or the multidrug resistance protein. W... | ['Base Sequence', 'Breast Neoplasms', 'Cloning, Molecular', 'DNA Probes', 'DNA, Neoplasm', 'Drug Resistance, Multiple', 'Gene Expression', 'Humans', 'Membrane Glycoproteins', 'Molecular Sequence Data', 'Muscle Proteins', 'Neoplasm Proteins', 'RNA, Long Noncoding', 'RNA, Untranslated', 'Tumor Cells, Cultured'] | 8,674,037 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.588.180', 'C17.800.090.500'], ['E05.393.220'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['D13.444.308.425'], ['G07.690.773.984.300'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.395.550', 'D12... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The interaction between a combined knitted silk scaffold and microporous silk sponge with human mesenchymal stem cells for ligament tissue engineering. | Cell seeding on knitted scaffolds often require a gel system, which was found to be practically unsuitable for anterior cruciate ligament (ACL) reconstruction as the cell-gel composite often gets dislodged from the scaffold in the in vivo dynamic situations. In order to solve this problem, we fabricated this combined s... | ['Base Sequence', 'DNA Primers', 'Humans', 'Immunohistochemistry', 'Ligaments', 'Mesenchymal Stem Cells', 'Reverse Transcriptase Polymerase Chain Reaction', 'Silk', 'Tissue Engineering'] | 17,997,479 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Cell adhesion. | Before cells can adhere to a surface, the atoms forming the adhesive bonds must come to within 0.5 nanometers of each other. Distances of this order may not correspond to the averaged electron micrographic data. The events leading to close approach of parts of cells are discussed in terms of electrical parameters, with... | ['Antimetabolites', 'Cell Adhesion', 'Cell Communication', 'Cell Membrane', 'Cell Movement', 'Chemical Phenomena', 'Chemistry, Physical', 'Electrophysiology', 'Endotoxins', 'Intercellular Junctions', 'Lysosomes', 'Stress, Mechanical'] | 273,572 | [['D27.505.519.186', 'D27.888.569.042'], ['G04.022'], ['G04.085'], ['A11.284.149'], ['G04.198', 'G07.568.500.180'], ['G02'], ['H01.181.529'], ['H01.158.344.528', 'H01.158.782.236'], ['D23.946.123.329'], ['A11.284.149.165.420'], ['A11.284.430.214.190.875.190.550'], ['G01.374.835']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Phylogeography of an asexual marine clam complex, Lasaea, in the northeastern Pacific based on cytochrome oxidase III sequence variation. | Northeastern Pacific populations of the intertidal marine clam Lasaea are exclusively composed of polyploid asexual clones that lack pelagic larval development. We investigated the phylogeographic structure of this clonal assemblage by assaying genetic divergence in 4 populations along 2000 km of the west coast of Nort... | ['Animals', 'Base Sequence', 'Bivalvia', 'DNA', 'Electron Transport Complex IV', 'Molecular Sequence Data', 'Pacific Ocean', 'Phylogeny', 'Sequence Alignment'] | 8,812,313 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.500.644.080'], ['D13.444.308'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12.776.543.585.450.250.875.484'], ['L01.453.245.667'], ['Z01.756.700'], ['G05.697',... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
[Bolande tumor in adults: apropos of a case]. | Bolande's tumour or congenital mesoblastic nephroma is essentially a tumour of infants under the age of one year and is rare in adults, in whom only 10 cases have been described. The authors report the 11th case in a 30-year-old woman, in whom a right renal tumour was discovered during ultrasonography at 34 weeks of pr... | ['Adult', 'Delivery, Obstetric', 'Female', 'Follow-Up Studies', 'Gonadal Steroid Hormones', 'Humans', 'Kidney Neoplasms', 'Neoplasm Recurrence, Local', 'Nephrectomy', 'Nephroma, Mesoblastic', 'Pregnancy', 'Pregnancy Complications, Neoplastic', 'Ultrasonography, Prenatal'] | 9,533,160 | [['M01.060.116'], ['E04.520.252'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D06.472.334.851'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['C04.697.655',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Development of drug-approval regulations for medical countermeasures against CBRN agents in Japan. | To develop approval regulations for drugs against chemical, biological, radiological, or nuclear (CBRN) agents in Japan, and to help inform arguments about the development of anti-CBRN agents, we analyzed documentation describing approval processes and data for drugs against CBRN agents. Sixteen countermeasure products... | ['Animals', 'Biohazard Release', 'Chemical Hazard Release', 'Disasters', 'Drug Approval', 'Drugs, Investigational', 'Humans', 'Japan', 'Off-Label Use', 'Radioactive Hazard Release', 'Terrorism', 'Time Factors', 'United States'] | 25,813,978 | [['B01.050'], ['N06.850.135.190'], ['N06.850.135.195'], ['N06.230.100'], ['E05.290.250', 'E05.337.300', 'I01.880.604.605.250.250'], ['D26.371'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['E02.319.307.500'], ['N06.850.135.848'], ['I01.198.240.856.800', 'I01.880.735.900.800'], ... | ['Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Synthesis of water-soluble (aminoalkyl)camptothecin analogues: inhibition of topoisomerase I and antitumor activity. | Water-soluble analogues of the antitumor alkaloid camptothecin (1) were prepared in which aminoalkyl groups were introduced into ring A or B. Most of the analogues were prepared by oxidation of camptothecin to 10-hydroxycamptothecin (2) followed by a Mannich reaction to give N-substituted 9-(aminomethyl)-10-hydroxycamp... | ['Animals', 'Antineoplastic Agents', 'Camptothecin', 'Cattle', 'Cell Line', 'Colonic Neoplasms', 'DNA, Superhelical', 'Drug Evaluation, Preclinical', 'Drug Screening Assays, Antitumor', 'Humans', 'Indicators and Reagents', 'Leukemia L1210', 'Lung Neoplasms', 'Melanoma, Experimental', 'Mice', 'Molecular Structure', 'Pla... | 1,846,923 | [['B01.050'], ['D27.505.954.248'], ['D03.132.151'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['D13.444.308.283.250', 'G02.111.570.820.486.212.250', 'G05.360.580.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serious laryngeal edema during endoscopic resection for squamous cell carcinoma of the esophagus. | The detection of early esophageal squamous cell carcinoma (ESCC) in patients following radiotherapy for squamous cell carcinoma of the head and neck (HNSCC) has increased with the development of endoscopic technologies. The aim of the current case - control study was to elucidate the risk factors of serious laryngeal e... | ['Aged', 'Carcinoma, Squamous Cell', 'Chi-Square Distribution', 'Esophageal Neoplasms', 'Esophagoscopy', 'Head and Neck Neoplasms', 'Humans', 'Laryngeal Edema', 'Male', 'Middle Aged', 'Neoplasms, Second Primary', 'Radiotherapy', 'Radiotherapy Dosage', 'Risk Assessment', 'Risk Factors', 'Statistics, Nonparametric'] | 23,296,362 | [['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E01.370.372.250.250.275', 'E01.370.388.250.250.250.26... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Environmental conditions for treatment of burned patients by the exposure method. | The influence of the thermal environment on evaporation and heat loss from patients with severe burns treated by exposure has been studied. Simple heat transfer equations can be used to predict changes resulting from alterations in environmental conditions and these have been tested using phantoms. The method relies up... | ['Adolescent', 'Adult', 'Body Temperature Regulation', 'Burns', 'Child', 'Environment, Controlled', 'Female', 'Humans', 'Male', 'Middle Aged', 'Skin Temperature', 'Water Loss, Insensible', 'Wound Healing'] | 1,418,502 | [['M01.060.057'], ['M01.060.116'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['C26.200'], ['M01.060.406'], ['N06.230.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G07.110.753', 'G13.750.844'], ['G02.111.635.500.750', 'G03.615.500.750', 'G07.410.810.500.750'], ['G16.762.891']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Partitioning of PAHs in pore water from mangrove wetlands in Shantou, China. | To investigate the trend of selected polycyclic aromatic hydrocarbons (PAHs) partitioning, fifteen pore water samples collected from the sediments of three mangrove wetlands were analyzed, and the partition coefficients and the partition model for the PAHs were determined by the correlation between K(oc) and octanol-wa... | ['Adsorption', 'China', 'Geologic Sediments', 'Polycyclic Aromatic Hydrocarbons', 'Water', 'Water Pollutants, Chemical', 'Wetlands'] | 25,450,913 | [['G01.030', 'G02.020'], ['Z01.252.474.164'], ['G01.311.330', 'G16.500.320'], ['D02.455.426.559.847', 'D04.615'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925'], ['D27.888.284.903.655'], ['G16.500.275.157.812', 'N06.230.124.625']] | ['Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Prenatal exposure to p,p'-DDE and p,p'-DDT in relation to lower respiratory tract infections in boys from a highly exposed area of Mexico. | BACKGROUND: Prenatal exposure to 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (p,p'-DDE), the major breakdown product of DDT, has been associated with recurrent lower respiratory tract infections (LRTIs) in infants. However, epidemiological investigations are limited.OBJECTIVE: To assess the association of prenatal exp... | ['Adolescent', 'Adult', 'Bronchitis', 'Child, Preschool', 'DDT', 'Dichlorodiphenyl Dichloroethylene', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Male', 'Mexico', 'Pneumonia', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Young Adult'] | 24,742,723 | [['M01.060.057'], ['M01.060.116'], ['C01.748.099', 'C08.127.446', 'C08.381.495.146', 'C08.730.099'], ['M01.060.406.448'], ['D02.455.526.439.255'], ['D02.455.526.439.292'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.06... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Composition and fatty acid content of rat ventral prostate phospholipids. | The major phospholipids of rat ventral prostate have been separated and examined using thin-layer chromatography, gas chromatography and mass spectrometry. The main phospholipid classes were choline and ethanolamine glycerophospholipids, accounting for 77.9% of total lipid phosphorus. The prostate also contained small ... | ['Animals', 'Chromatography, Gas', 'Fatty Acids', 'Male', 'Mass Spectrometry', 'Phosphatidylcholines', 'Phosphatidylethanolamines', 'Phospholipids', 'Prostate', 'Rats', 'Rats, Inbred Strains', 'Sphingomyelins'] | 3,768,387 | [['B01.050'], ['E05.196.181.349'], ['D10.251'], ['E05.196.566'], ['D10.570.755.375.760.400.800'], ['D10.570.755.375.760.400.840'], ['D10.570.755'], ['A05.360.444.575', 'A10.336.707'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D09.400.410.4... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Knowledge on legislation of abortion and experience of abortion among female youth in Nepal: A cross sectional study. | BACKGROUND: Abortion has been legal in Nepal since 2002 and the country has made striking progress in rolling out induced abortion services. It led to well-known changes in reproductive behavior, however knowledge about legislation and abortion experience by female youth has been least investigated. This paper is an at... | ['Abortion, Criminal', 'Abortion, Induced', 'Abortion, Legal', 'Adolescent', 'Adult', 'Cross-Sectional Studies', 'Developing Countries', 'Female', 'Health Care Surveys', 'Health Knowledge, Attitudes, Practice', 'Health Literacy', 'Humans', 'Logistic Models', 'Needs Assessment', 'Nepal', 'Patient Acceptance of Health Ca... | 27,117,480 | [['I01.198.240.089'], ['E04.520.050'], ['E04.520.050.055'], ['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.615.500.300'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['F01.100.150... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Continuous models of population-level heterogeneity inform analysis of animal dispersal and migration. | Behavioral heterogeneity among individuals is a universal feature of natural populations. Most diffusion-based models of animal dispersal, however, implicitly assume homogeneous movement parameters within a population. Recent attempts to consider the effect of heterogeneous populations on dispersal distributions have b... | ['Animal Migration', 'Animals', 'Fishes', 'Models, Biological', 'Population Dynamics', 'Time Factors'] | 19,739,385 | [['F01.145.113.069.500'], ['B01.050'], ['B01.050.150.900.493'], ['E05.599.395'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['G01.910.857']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Subunit structure and dissociation of Callinectes sapidus hemocyanin. | The hemocyanin of the blue crab, Callinectes sapidus has two major components sedimenting with approximate sedimentation coefficients of 17 S and 25 S. Molecular weight data based on light scattering and sedimentation equilibrium measurements at pH 7.8 suggest that the two components have molecular weights of approxima... | ['Animals', 'Brachyura', 'Chemical Phenomena', 'Chemistry', 'Circular Dichroism', 'Hemocyanins', 'Light', 'Macromolecular Substances', 'Mathematics', 'Molecular Weight', 'Optical Rotatory Dispersion', 'Scattering, Radiation'] | 7,213,799 | [['B01.050'], ['B01.050.500.131.365.190.110'], ['G02'], ['H01.181'], ['E05.196.867.151'], ['D12.776.093.375', 'D12.776.556.462', 'D23.767.482'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D05'], ['H01.548'], ['G02.494'], ['E05.196.867.576'], ['E05.196.822', 'G01.867']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A study of attempted suicides in urban versus rural areas, with a follow-up. | The group of subjects consisted of 44 patients (attempters) who were admitted to hospital for treatment because of attempted suicide during a 3-month period in Norther Savo (in Eastern Finland), another 44 patients (non-attempters) admitted to hospital in the same period for other reasons serving as controls. The numbe... | ['Adult', 'Aged', 'Alcoholism', 'Family Characteristics', 'Female', 'Finland', 'Follow-Up Studies', 'Humans', 'Male', 'Marriage', 'Middle Aged', 'Prognosis', 'Rural Population', 'Schizophrenia', 'Substance-Related Disorders', 'Suicide, Attempted', 'Urban Population'] | 1,189,956 | [['M01.060.116'], ['M01.060.116.100'], ['C25.775.100.250', 'F03.900.100.350'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['Z01.542.816.186'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Disruption of TGF-beta signaling prevents the generation of tumor-sensitized regulatory T cells and facilitates therapeutic antitumor immunity. | Regulatory T (Treg) cells represent a major roadblock to the induction of antitumor immunity through vaccine approaches. TGF-beta is a cytokine implicated in the generation and maintenance of Treg cells, as well as in their suppressive function. These experiments examined whether the generation of tumor-sensitized Treg... | ['Animals', 'Antigen Presentation', 'Antigens, Neoplasm', 'Cells, Cultured', 'Immunity', 'Immunotherapy, Adoptive', 'Mice', 'Mice, Knockout', 'Neoplasms, Experimental', 'Signal Transduction', 'T-Lymphocytes, Regulatory', 'Transforming Growth Factor beta'] | 19,692,636 | [['B01.050'], ['G12.119', 'G12.450.050.400.070'], ['D23.050.285'], ['A11.251'], ['G12.450'], ['E02.095.465.425.400.330.050.400', 'E05.478.550.520.050.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.313.992.635.505.50... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Maternal Infections That Would Warrant Antibiotic Use Antepartum or Peripartum Are Not a Risk Factor for the Development of IBD: A Population-Based Analysis. | BACKGROUND: We aimed to determine whether maternal antenatal or perinatal infections (and thereby use of antibiotics) increase the risk of developing inflammatory bowel disease (IBD) in their offspring.METHODS: The University of Manitoba IBD Epidemiology Database contains records of all Manitobans diagnosed with IBD fr... | ['Anti-Bacterial Agents', 'Case-Control Studies', 'Colitis, Ulcerative', 'Crohn Disease', 'Female', 'Humans', 'Inflammatory Bowel Diseases', 'Male', 'Manitoba', 'Peripartum Period', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Prenatal Exposure Delayed Effects', 'Risk Factors'] | 28,195,851 | [['D27.505.954.122.085'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.205.731', ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Syphilitic cervicitis simulating stage II cervical cancer. Report of two cases with cytologic findings. | Two women, ages 42 and 46, each had a cervical mass that clinically was grossly compatible with invasive carcinoma. Colposcopy supported the clinical impression. Weeks after the women were examined, it was determined that the masses represented syphilitic cervicitis. This entity has received almost no attention in the ... | ['Adult', 'Diagnosis, Differential', 'Female', 'Humans', 'Middle Aged', 'Neoplasm Staging', 'Spirochaetaceae', 'Syphilis', 'Uterine Cervical Neoplasms', 'Uterine Cervicitis', 'Vaginal Smears'] | 8,526,206 | [['M01.060.116'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['B03.440.425.410.711', 'B03.851.595'], ['C01.150.252.400.794.840.500', 'C01.150.252.400.840.500', 'C01.150.252.734.859', 'C01.221.812.281.859', 'C01.778.281.859', 'C12.294.668.281.859', 'C13.351.500.71... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ultrasound-Guided Retrieval and Position Replacement of a Dislodged Fetal Pleuro-Amniotic Shunt: A Novel Approach for a Known Complication of Feto-Amniotic Shunting. | Untreated fetal pleural effusion can cause significant perinatal morbidity and mortality. Treatment of pleural effusions with pleuro-amniotic shunting has been shown to improve outcomes. Pleuro-amniotic shunting is associated with complications including ruptured membranes, preterm labor and shunt dislodgement into eit... | ['Adult', 'Female', 'Fetal Diseases', 'Fetal Therapies', 'Humans', 'Pleural Effusion', 'Pregnancy', 'Ultrasonography, Interventional', 'Ultrasonography, Prenatal'] | 25,660,293 | [['M01.060.116'], ['C13.703.277', 'C16.300'], ['E02.467'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.528.652'], ['G08.686.784.769'], ['E01.370.350.850.855', 'E04.502.890'], ['E01.370.350.850.865', 'E01.370.378.630.865']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A phase II trial of arsenic trioxide in patients with metastatic melanoma. | BACKGROUND: Arsenic trioxide induces growth inhibition and apoptosis in human melanoma cell lines. Therefore, a Phase II trial was conducted to evaluate the efficacy and toxicity of single-agent arsenic trioxide in patients with Stage IV melanoma.METHODS: Twenty patients, 10 with metastatic melanoma of cutaneous origin... | ['Adult', 'Aged', 'Antineoplastic Agents', 'Arsenic Trioxide', 'Arsenicals', 'Choroid Neoplasms', 'Female', 'Humans', 'Lymphatic Metastasis', 'Male', 'Melanoma', 'Middle Aged', 'Oxides', 'Skin Neoplasms', 'Survival Rate', 'Treatment Outcome'] | 16,130,126 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['D01.075.038', 'D01.650.550.125'], ['D01.075', 'D02.129'], ['C04.588.364.978.223', 'C11.319.494.198', 'C11.941.160.238', 'C11.941.855.198'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['C04.557.465.625.650.510... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[ANTIBIOTIC USE IN COMMUNITY HEALTHCARE IN ISRAEL AS REFLECTED IN THE NATIONAL PROGRAM FOR QUALITY INDICATORS]. | AIMS: We sought to evaluate the extent of overall and second-line systemic antibiotic use in the Israeli community, to compare them to international data and to monitor temporal trends.BACKGROUND: Antibiotic overuse is prevalent and has grave implications, primarily the emergence of resistant pathogens - an urgent publ... | ['Anti-Bacterial Agents', 'Antimicrobial Stewardship', 'Community Health Services', 'Female', 'Humans', 'Israel', 'Male', "Practice Patterns, Physicians'", 'Public Health', 'Quality Indicators, Health Care'] | 31,104,389 | [['D27.505.954.122.085'], ['N04.452.706.477.400.500', 'N04.761.879.300.500', 'N05.700.900.300.500'], ['N02.421.143'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.375'], ['N04.590.374.577', 'N05.300.625'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['N04.761.789', 'N05.715.760']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
[Multiplanar spiral CT in the diagnosis of pancreatic tumors]. | PURPOSE: Investigation of the capabilities of MSCT and its value for the staging of pancreatic carcinomas.METHODS: 50 Patients with suspected pancreatic carcinoma were examined with a biphasic multislice-spiral-CT protocol: slice collimation 4 x 1 mm, Pitch 3.5-4 mm. After administration of 120 ml contrast medium and 5... | ['Administration, Oral', 'Carcinoma', 'Contrast Media', 'Humans', 'Image Processing, Computer-Assisted', 'Infusions, Intravenous', 'Lymphatic Metastasis', 'Neoplasm Staging', 'Pancreas', 'Pancreatic Neoplasms', 'Tomography, X-Ray Computed'] | 10,602,801 | [['E02.319.267.100'], ['C04.557.470.200'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['C04.697.650.560', 'C23.550.727.650.560'], ['E01.789.625'], ['A03.734'], ['C04.588.274.761', 'C04.588.322.475', 'C06.301.761',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Control of membrane fouling during hyperhaline municipal wastewater treatment using a pilot-scale anoxic/aerobic-membrane bioreactor system. | Membrane fouling limits the effects of long-term stable operation of membrane bioreactor (MBR). Control of membrane fouling can extend the membrane life and reduce water treatment cost effectively. A pilot scale anoxic/aerobic-membrane bioreactor (A/O-MBR, 40 L/hr) was used to treat the hyperhaline municipal sewage fro... | ['Bioreactors', 'China', 'Membranes, Artificial', 'Pilot Projects', 'Sewage', 'Waste Disposal, Fluid', 'Water Pollutants, Chemical'] | 22,432,256 | [['E07.115', 'J01.897.120.115'], ['Z01.252.474.164'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['D20.944.932.500'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D27.888.284.903.655']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Studies on the release of proteolytic enzymes during synovium-induced cartilage breakdown in vitro and the actions of anti-inflammatory drugs. | Pig articular cartilage, overlaid with a minced preparation of synovium from the same joint, underwent extensive matrix degradation during a two-week culture period. This degradation was associated with de novo synthesis by the synovium of specific neutral proteoglycan- and collagen-degrading enzymes. Both enzymes exhi... | ['Animals', 'Anti-Inflammatory Agents', 'Cartilage, Articular', 'Dexamethasone', 'Endopeptidases', 'In Vitro Techniques', 'Metalloendopeptidases', 'Microbial Collagenase', 'Swine', 'Synovial Membrane'] | 6,324,820 | [['B01.050'], ['D27.505.954.158'], ['A02.165.407.150', 'A02.835.583.192'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D08.811.277.656.300'], ['E05.481'], ['D08.811.277.656.300.480', 'D08.811.277.656.675.374'], ['D08.811.277.656.300.480.205.500', 'D08.811.277.656.675.374.205.500'], ['B01.050.150.900.649.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elderly patients undergoing cystectomy, comparing preoperative American Society of Anesthesiology and Eastern Cooperative Oncology Group scores and operative approaches. | OBJECTIVE: To evaluate preoperative scoring systems and operative management and their relation to complications in patients older than 75 years undergoing cystectomy at two academic institutions.METHODS: In total, 212 patients aged 75-95 years with muscle invasive bladder cancer underwent cystectomy at the University ... | ['Aged', 'Aged, 80 and over', 'Cystectomy', 'Geriatric Assessment', 'Humans', 'Neoplasm Invasiveness', 'Postoperative Complications', 'Preoperative Period', 'Retrospective Studies', 'Urinary Bladder Neoplasms'] | 31,364,495 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.950.774.150'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.645', 'C23.550.727.645'], ['C23.550.767'], ['E04.614.937', 'N... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Concurrent changes in eccentric hamstring strength and knee joint kinematics induced by soccer-specific fatigue. | OBJECTIVES: To investigate the influence of soccer-specific fatigue on concurrent changes in knee joint kinematics and hamstring strength, given the increased risk of injury during the latter stages of match-play and the prevalence of knee joint and hamstring muscular injury.DESIGN: Repeated measures, randomized order ... | ['Adult', 'Biomechanical Phenomena', 'Hamstring Muscles', 'Humans', 'Knee Joint', 'Male', 'Muscle Fatigue', 'Muscle Strength', 'Random Allocation', 'Soccer', 'Young Adult'] | 30,802,762 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['A02.633.567.450', 'A10.690.552.500.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['G11.427.550'], ['E01.370.600.425', 'G11.427.560'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['I03.450.642.845... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Potentiometric quasi-array employing calixarene derivatives for the high-throughput similarity/diversity screening of beta-adrenergic and beta-blocking chiral drugs by HPLC. | Performance of potentiometric quasi-array detection system consisted with the seven poly (vinyl chloride) (PVC) based liquid membrane electrodes in the cation-exchange HPLC using acetonitrile--40 mM phosphoric acid (15 : 85, v/v, pH* 2.35) for assessing of molecular similarity/diversity in a mini-library of beta-adrene... | ['Adrenergic beta-Antagonists', 'Calixarenes', 'Chemical Phenomena', 'Chemistry, Physical', 'Chromatography, High Pressure Liquid', 'Drug Evaluation, Preclinical', 'Electrodes', 'Hydrogen-Ion Concentration', 'Membranes, Artificial', 'Polycyclic Compounds', 'Potentiometry', 'Quantitative Structure-Activity Relationship'... | 15,200,382 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['D04.345.025'], ['G02'], ['H01.181.529'], ['E05.196.181.400.300'], ['E05.290.750', 'E05.337.550'], ['E07.305.250'], ['G02.300'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['D04'], ['E05.196.922.750', 'E05.301.710'], ['G02.111.830.500', 'G07.690.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Factors associated with unprotected anal intercourse among men who have sex with men in Liaoning Province, China. | BACKGROUND: HIV prevalence among men who have sex with men (MSM) has increased rapidly. MSM may play a bridging role in the spread of HIV and other STDs from the high-risk population to the general population. Interventions to reduce high-risk behavior are the key to controlling the spreading of HIV in the MSM populati... | ['Adult', 'Aged', 'Cross-Sectional Studies', 'Homosexuality, Male', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Sexual Behavior', 'Surveys and Questionnaires', 'Young Adult'] | 23,209,757 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.802.975.500.600', 'G08.686.867.500.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Real-world utilization of andexanet alfa. | OBJECTIVE: In 2018, the FDA approved andexanet alfa for the reversal of life-threatening hemorrhages in patients anticoagulated with apixaban or rivaroxaban. Yet, cost-effective factor Xa inhibitor reversal remains controversial. The objective of this study was to describe real world utilization of andexanet alfa.METHO... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anticoagulants', 'Factor Xa', 'Gastrointestinal Hemorrhage', 'Hemorrhage', 'Hemostatics', 'Humans', 'Intracranial Hemorrhages', 'Male', 'Middle Aged', 'Pyrazoles', 'Pyridones', 'Recombinant Proteins', 'Retrospective Studies', 'Rivaroxaban', 'Surgical Procedures, Operative', 'Trea... | 31,870,672 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.502.119'], ['D08.811.277.656.300.760.315', 'D08.811.277.656.959.350.315', 'D12.776.124.125.400.315', 'D23.119.400.315'], ['C06.405.227', 'C23.550.414.788'], ['C23.550.414'], ['D27.505.954.502.270.463'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Maternal obese-type gut microbiota differentially impact cognition, anxiety and compulsive behavior in male and female offspring in mice. | Maternal obesity is known to predispose offspring to metabolic and neurodevelopmental abnormalities. While the mechanisms underlying these phenomena are unclear, high fat diets dramatically alter intestinal microbiota, and gut microbiota can impact physiological function. To determine if maternal diet-induced gut dysbi... | ['Adiposity', 'Animal Communication', 'Animals', 'Animals, Newborn', 'Anxiety', 'Cognition', 'Compulsive Behavior', 'Female', 'Gastrointestinal Microbiome', 'Male', 'Maternal Nutritional Physiological Phenomena', 'Mice, Inbred C57BL', 'Obesity', 'Pregnancy', 'Prenatal Exposure Delayed Effects'] | 28,441,394 | [['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['F01.145.113.055'], ['B01.050'], ['B01.050.050.282'], ['F01.470.132'], ['F02.463.188'], ['F01.145.527.100'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['G07.203.650.566'], ['B01.0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Genetics of hypophosphatasia. | Hypophosphatasia (HPP) is a rare inherited disorder primarily affecting bone and dental mineralization. Although there is a continuum in the severity of the disease, clinical forms may be arbitrarily distinguished on the basis of age at onset and the presence or absence of bone symptoms: perinatal, infantile, juvenile,... | ['Adult', 'Alkaline Phosphatase', 'Alleles', 'Biomarkers', 'France', 'Genetic Counseling', 'Genotype', 'Humans', 'Hypophosphatasia', 'Inheritance Patterns', 'Mutation, Missense', 'Prevalence', 'Severity of Illness Index'] | 29,405,932 | [['M01.060.116'], ['D08.811.277.352.650.035'], ['G05.360.340.024.340.030'], ['D23.101'], ['Z01.542.286'], ['H01.158.273.343.385.500.384', 'N02.421.308.400'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.565.618.482', 'C18.452.648.618.482'], ['G05.420'], ['G05.365.590.650'], ['E05.318.308.985.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Sexual selection accelerates signal evolution during speciation in birds. | Sexual selection is proposed to be an important driver of diversification in animal systems, yet previous tests of this hypothesis have produced mixed results and the mechanisms involved remain unclear. Here, we use a novel phylogenetic approach to assess the influence of sexual selection on patterns of evolutionary ch... | ['Animals', 'Feathers', 'Female', 'Genetic Speciation', 'Male', 'Mating Preference, Animal', 'Passeriformes', 'Phenotype', 'Phylogeny'] | 23,864,596 | [['B01.050'], ['A13.370'], ['G05.045.350', 'G16.075.350'], ['F01.145.113.252.748.300'], ['B01.050.150.900.248.620'], ['G05.695'], ['G05.697', 'G16.075.605', 'L01.100.697']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Polymorphism of human salivary amylase: a preliminary communication. | Variation of human salivary amylase isoenzymes was investigated by isoelectric focusing on thin-layer polyacrylamide gel. Preliminary studies indicate a genetic polymorphism. | ['Amylases', 'Electrophoresis, Polyacrylamide Gel', 'Humans', 'Polymorphism, Genetic', 'Saliva'] | 738,721 | [['D08.811.277.450.066'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.795'], ['A12.200.666']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of Renal Artery Angulation on Procedure Efficiency During Fenestrated and Snorkel/Chimney Endovascular Aneurysm Repair. | PURPOSE: To determine the impact of renal artery angulation on time to successful renal artery cannulation and procedure efficiency during fenestrated and snorkel/chimney endovascular aneurysm repair (EVAR).METHODS: The imaging and procedure logs of 77 patients (mean age 74.2 years; 63 men) who underwent complex EVAR (... | ['Aged', 'Aortic Aneurysm, Abdominal', 'Aortography', 'Blood Vessel Prosthesis', 'Blood Vessel Prosthesis Implantation', 'Endovascular Procedures', 'Female', 'Fluoroscopy', 'Humans', 'Male', 'Renal Artery', 'Retrospective Studies', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 26,045,462 | [['M01.060.116.100'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['E01.370.350.700.060.070', 'E01.370.370.050.070'], ['E07.695.110'], ['E04.100.814.868.500', 'E04.650.200'], ['E04.100.814.529', 'E04.502.382'], ['E01.370.350.700.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.745'], ['E05.318.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Guided medication dosing for elderly emergency patients using real-time, computerized decision support. | OBJECTIVE: To evaluate the impact of a real-time computerized decision support tool in the emergency department that guides medication dosing for the elderly on physician ordering behavior and on adverse drug events (ADEs).DESIGN: A prospective controlled trial was conducted over 26 weeks. The status of the decision su... | ['Aged', 'Computer Systems', 'Decision Support Systems, Clinical', 'Drug Therapy, Computer-Assisted', 'Drug-Related Side Effects and Adverse Reactions', 'Emergency Service, Hospital', 'Hospitals, Urban', 'Humans', 'Knowledge Bases', 'Pharmaceutical Preparations', 'Prospective Studies'] | 22,052,899 | [['M01.060.116.100'], ['L01.224.230'], ['L01.313.500.750.300.190'], ['E02.319.335', 'L01.313.500.750.100.710.180'], ['C25.100'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['N02.278.421.660'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.050.375.480', 'L01.313.500.750.300.5... | ['Named Groups [M]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Positive selection for CD90 as a purging option in acute myeloid leukemia stem cell transplants. | BACKGROUND: Several studies showed the benefit of purging of acute myeloid leukemia (AML) stem cell transplants. We reported previously that purging by positive selection of CD34+ and CD133+ cells resulted in a 3-4 log tumor cell reduction (TCR) in CD34- and/or CD133- AML, but has been shown to be potentially applicabl... | ['Antigens, CD34', 'Biomarkers, Tumor', 'Bone Marrow Purging', 'Female', 'Flow Cytometry', 'Hematopoietic Stem Cells', 'Humans', 'Immunophenotyping', 'Leukemia, Myeloid, Acute', 'Male', 'Middle Aged', 'Peripheral Blood Stem Cell Transplantation', 'Thy-1 Antigens'] | 18,061,946 | [['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['D23.101.140'], ['E02.120.142'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050.1... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Insulin-like growth factor-I regulates pro-B cell differentiation. | Progression of B-lymphocyte development in the bone marrow of postnatal mammals is marked by progressive rearrangement and expression of immunoglobulin (Ig) heavy- and light-chain genes. Following productive VHDJH gene rearrangement in the Ig heavy-chain gene complex, mu-heavy chain is the first Ig gene product express... | ['Animals', 'B-Lymphocytes', 'Base Sequence', 'Cell Differentiation', 'Hematopoiesis', 'Hematopoietic Stem Cells', 'Insulin-Like Growth Factor I', 'Lymphocyte Activation', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Molecular Sequence Data'] | 1,515,639 | [['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.152'], ['G04.152.825', 'G09.188.343'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['D12.644.276.937.400', 'D12.7... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The divergence between human and baboon globin genes. | Complementary DNA (cDNA) was prepared with viral RNA-directed DNA polymerase from purified baboon globin messenger RNA (mRNA). Homologous and heterologous hybrids between human and baboon mRNAs and cDNAs were compared for extent of hybridisation and thermal stability. Higher mRNA inputs to the hybridizations were requi... | ['Animals', 'DNA', 'DNA, Circular', 'Genes', 'Globins', 'Humans', 'Kinetics', 'Nucleic Acid Denaturation', 'Nucleic Acid Hybridization', 'Papio', 'Protein Biosynthesis', 'RNA, Messenger', 'Reticulocytes', 'Species Specificity', 'Transcription, Genetic'] | 1,276,203 | [['B01.050'], ['D13.444.308'], ['D13.444.308.283', 'G02.111.570.820.486.212', 'G05.360.580.156'], ['G05.360.340.024.340'], ['D12.776.422.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['E05.393.640', 'G02.111.603', 'G05.627'], ['E05.393.661', 'G02.111.611'], ['B01.050.150.900.64... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Socioeconomic factors affecting farmers' perceptions of land degradation and stonewall terraces in central Palestine. | Land degradation by soil erosion is a socioeconomic and environmental problem facing many developing countries. Application of stonewall terraces for soil moisture conservation is vital to reducing the environmental impacts of this phenomenon. To this end, a field plot experiment was conducted in the study area along w... | ['Agriculture', 'Attitude', 'Climate', 'Conservation of Natural Resources', 'Environment Design', 'Humans', 'Middle East', 'Ownership', 'Social Conditions', 'Soil', 'Triticum', 'Urbanization'] | 16,456,634 | [['J01.040'], ['F01.100'], ['G16.500.275.071', 'N06.230.300.100.250'], ['J01.256', 'N06.230.080'], ['I01.283', 'I01.880.709.359', 'N06.230.145'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500'], ['I01.880.604.583.594', 'N04.452.633'], ['I01.880.853.450', 'N01.824.827'], ['D20.721', 'G01.311.820', '... | ['Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
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