Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Publication rates of abstracts presented at the 1993 annual Academy meeting. | What percent of abstracts presented at the American Academy of Orthopaedic Surgeons annual meeting are submitted, survive peer review, and eventually are published? The answer to this fundamental question is important because many national meeting attendees use the unscrutinized information that is presented to alter t... | ['Abstracting and Indexing', 'Congresses as Topic', 'Humans', 'Orthopedics', 'Publishing', 'United States'] | 10,078,150 | [['L01.453.245.100'], ['N03.540.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.494'], ['L01.737'], ['Z01.107.567.875']] | ['Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Effectiveness of a low contrast load CT angiography protocol in octogenarians and nonagenarians being evaluated for transcatheter aortic valve replacement. | INTRODUCTION: Transcatheter aortic valve replacement (TAVR) typically requires computed tomographic angiography (CTA) for aortoiliofemoral assessment to determine feasibility of a transfemoral approach, although many candidates being considered for TAVR are at increased risk of contrast-induced nephropathy (CIN).OBJECT... | ['Aged', 'Aged, 80 and over', 'Angiography', 'Aortic Valve Stenosis', 'Contrast Media', 'Feasibility Studies', 'Female', 'Humans', 'Male', 'Retrospective Studies', 'Tomography, X-Ray Computed', 'Transcatheter Aortic Valve Replacement'] | 25,982,494 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.700.060', 'E01.370.370.050'], ['C14.280.484.048.750', 'C14.280.955.249'], ['D27.505.259.500', 'D27.720.259'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Systemic bleeding including pulmonary haemorrhage following hump-nosed pit viper (Hypnale hypnale) envenoming: A case report from Sri Lanka. | Out of seven venomous land snake species of Sri Lanka, hump-nosed pit viper (Hypnale spp.) causes the commonest venomous snakebites. It is widely distributed all over the country except in the peninsula of Jaffna. The genus has three species naming H. hypnale, H. zara and H. nepa. They frequently cause local envenoming... | ['Aged', 'Animals', 'Crotalid Venoms', 'Crotalinae', 'Fatal Outcome', 'Hemorrhage', 'Humans', 'Lung Diseases', 'Male', 'Snake Bites', 'Sri Lanka'] | 31,513,811 | [['M01.060.116.100'], ['B01.050'], ['D20.888.850.960.200', 'D23.946.833.850.960.200'], ['B01.050.150.900.833.672.125.937.240'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381'],... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mutations in TRAPPC12 Manifest in Progressive Childhood Encephalopathy and Golgi Dysfunction. | Progressive childhood encephalopathy is an etiologically heterogeneous condition characterized by progressive central nervous system dysfunction in association with a broad range of morbidity and mortality. The causes of encephalopathy can be either non-genetic or genetic. Identifying the genetic causes and dissecting ... | ['Atrophy', 'Base Sequence', 'Brain', 'Brain Diseases', 'Cells, Cultured', 'Child, Preschool', 'Endoplasmic Reticulum', 'Exome', 'Female', 'Genetic Predisposition to Disease', 'Golgi Apparatus', 'Humans', 'Infant', 'Magnetic Resonance Imaging', 'Male', 'Membrane Transport Proteins', 'Protein Transport', 'Sequence Analy... | 28,777,934 | [['C23.300.070'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A08.186.211'], ['C10.228.140'], ['A11.251'], ['M01.060.406.448'], ['A11.284.430.214.190.875.248'], ['G05.360.340.011'], ['C23.550.291.687.500', 'G05.380.355'], ['A11.284.430.214.190.875.336'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Systemic uptake of 5-aminosalicylic acid from olsalazine and eudragit L coated mesalazine in patients with ulcerative colitis in remission. | UNLABELLED: Aminosalicylates are used to maintain remission in patients with ulcerative colitis. Since there are potential systemic side effects of 5-aminosalicylic acid (5-ASA) and long term treatment is necessary for maintenance therapy preparations with low rates of absorption in the small intestine would be optimal... | ['Adult', 'Aged', 'Aminosalicylic Acids', 'Anti-Inflammatory Agents, Non-Steroidal', 'Biotransformation', 'Colitis, Ulcerative', 'Convalescence', 'Cross-Over Studies', 'Delayed-Action Preparations', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Female', 'Humans', 'Intestinal Absorption', 'Male', ... | 8,686,349 | [['M01.060.116'], ['M01.060.116.100'], ['D02.241.223.100.300.595.100', 'D02.241.511.390.595.100', 'D02.455.426.559.389.127.281.595.100', 'D02.455.426.559.389.657.410.595.100'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['C06.405.205... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
The subcellular localization of transglutaminase in normal liver and in glucagon-treated and partial hepatectomized rats. | Rat liver was homogenized in isotonic sucrose and subjected to analytical subcellular fractionation by sucrose density-gradient centrifugation. Transglutaminase, when assayed with putrescine and dimethylcasein as substrates, showed three distinct localizations, cytosol (73%), plasma membrane (20%), and nuclei (7%). The... | ['Acyltransferases', 'Animals', 'Cell Fractionation', 'Cell Membrane', 'Cell Nucleus', 'Cytosol', 'Glucagon', 'Hepatectomy', 'Liver', 'Male', 'Rats', 'Rats, Inbred Strains', 'Transglutaminases'] | 6,141,821 | [['D08.811.913.050'], ['B01.050'], ['E05.242.251'], ['A11.284.149'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['E04.210.556'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.700'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Atopic keratoconjunctivitis: probably a risk factor for the development of conjuntival carcinoma]. | BACKGROUND: Almost half of the patients with atopic dermatitis experience chronic inflammation of the eyelids, the conjunctiva and the cornea. Chronic inflammation is a possible cause for the development of malignancies, especially if associated with some kind of immunological defect as in atopic patients. So far, a co... | ['Adult', 'Aged', 'Conjunctival Neoplasms', 'Conjunctivitis, Allergic', 'Disease Susceptibility', 'Female', 'Humans', 'Keratoconjunctivitis', 'Male', 'Middle Aged', 'Precancerous Conditions', 'Risk Assessment', 'Statistics as Topic'] | 14,618,353 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.364.235', 'C11.187.169', 'C11.319.217'], ['C11.187.183.200', 'C20.543.480.200'], ['C23.550.291.687', 'G07.100.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.187.183.394', 'C11.204.564.585'], ['M01.060.116.630'], ['C04.834'], ['E05.318.740.600.800.715', 'N0... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Media coverage and children's reactions to disaster with implications for primary care and public health. | To address the potential for media coverage of traumatic events to generate fear reactions in children, we examined exposure and reactions to media coverage of the 1995 Oklahoma City bombing in children attending a middle school 100 miles from the disaster site two and three years after the event. Many of the children ... | ['Adaptation, Psychological', 'Age Factors', 'Child', 'Child Welfare', 'Disasters', 'Humans', 'Mass Media', 'Primary Health Care', 'Psychometrics', 'Public Health', 'Social Perception', 'Stress Disorders, Post-Traumatic', 'Stress, Psychological', 'Terrorism'] | 19,177,993 | [['F01.058'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['I01.880.787.293'], ['N06.230.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.590'], ['N04.590.233.727'], ['F04.711.780'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['F02.463.593.752'], ['F03.950.750.500'], ['F01.145.126.990', 'F... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Ecological engineering practices for the reduction of excess nitrogen in human-influenced landscapes: a guide for watershed managers. | Excess nitrogen (N) in freshwater systems, estuaries, and coastal areas has well-documented deleterious effects on ecosystems. Ecological engineering practices (EEPs) may be effective at decreasing nonpoint source N leaching to surface and groundwater. However, few studies have synthesized current knowledge about the f... | ['Ecology', 'Ecosystem', 'Nitrogen', 'Water Pollutants, Chemical', 'Water Supply', 'Wetlands'] | 23,180,248 | [['H01.158.273.248', 'H01.277.249'], ['G16.500.275.157', 'N06.230.124'], ['D01.268.604', 'D01.362.625'], ['D27.888.284.903.655'], ['J01.293.821.500'], ['G16.500.275.157.812', 'N06.230.124.625']] | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
A simple chromatographic method for purification of egg lecithin. | Egg lecithin was purified from the CdCl2-lecithin complex by column chromatography on Alumina. The yield from 5 eggs was 2.8 g. The purified lecithin had correct chemical values for pure lecithin and a fatty acid composition similar to lecithin prepared by other methods. The method probably can be adapted for purificat... | ['Aluminum Oxide', 'Chromatography, Gas', 'Chromatography, Gel', 'Chromatography, Thin Layer', 'Egg Yolk', 'Fatty Acids', 'Female', 'Phosphatidylcholines'] | 7,190,638 | [['D01.056.050', 'D01.650.550.050'], ['E05.196.181.349'], ['E05.196.181.400.250'], ['E05.196.181.400.537'], ['A16.690.325', 'G07.203.300.470.800', 'J02.500.470.800'], ['D10.251'], ['D10.570.755.375.760.400.800']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Dose reduction in helical CT: dynamically adjustable z-axis X-ray beam collimation. | OBJECTIVE: The purpose of this study was to measure the dose reduction achieved with dynamically adjustable z-axis collimation.MATERIALS AND METHODS: A commercial CT system was used to acquire CT scans with and without dynamic z-axis collimation. Dose reduction was measured as a function of pitch, scan length, and posi... | ['Humans', 'Phantoms, Imaging', 'Radiation Dosage', 'Radiation Protection', 'Tomography, Spiral Computed'] | 20,028,890 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.671'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['N06.850.810.425'], ['E01.370.350.350.810.800', 'E01.370.350.600.350.700.810.800', 'E01.370.350.700.700.810.800', 'E01.370.350.700.810.810.800', 'E01.370.350.825.810.810.800']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Establishment of bovine mammary epithelial cells (MAC-T): an in vitro model for bovine lactation. | The hallmark of differentiated mammary epithelial cells is a copious secretion of milk-specific components regulated by lactogenic hormones. We describe an established clonal cell line produced from primary bovine mammary alveolar cells (MAC-T) by stable transfection with SV-40 large T-antigen. MAC-T cells show a popul... | ['Animals', 'Antigens, Polyomavirus Transforming', 'Caseins', 'Cattle', 'Cell Division', 'Cell Transformation, Neoplastic', 'Clone Cells', 'Culture Techniques', 'Epithelial Cells', 'Epithelium', 'Female', 'Kinetics', 'Lactation', 'Mammary Glands, Animal', 'Models, Biological', 'Molecular Weight', 'Simian virus 40', 'Te... | 1,659,986 | [['B01.050'], ['D12.776.624.664.520.090', 'D12.776.964.700.090', 'D23.050.285.062.090', 'D23.050.327.062.090'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['B01.050.150.900.649.313.500.380.271'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['C04.697.098.500', 'C23.550.727.098.500'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Acting and Feeling Like a Vulnerable Child, an Internalized "Bad" Parent, or a Healthy Person: The Assessment of Schema Modes in Non-Clinical Adolescents. | Schema modes are strong, predominant, momentary (state-like) emotional and cognitive states, and maladaptive coping responses that occur when underlying personality schemas are activated by emotional events. The current study employed the Schema Mode Inventory for Adolescents (SMI-A) to assess such schema modes in a sa... | ['Adaptation, Psychological', 'Adolescent', 'Child', 'Defense Mechanisms', 'Emotions', 'Factor Analysis, Statistical', 'Female', 'Humans', 'Male', 'Parenting', 'Parents', 'Personality', 'Personality Disorders', 'Personality Inventory', 'Psychometrics', 'Quality of Life', 'Reproducibility of Results', 'Vulnerable Popula... | 26,305,395 | [['F01.058'], ['M01.060.057'], ['M01.060.406'], ['F01.393'], ['F01.470'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.370.310'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['F01.752'], ['F03.675'], ['F04.711.647.51... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Correlation between pigment production and amino acid requirements in Bacillus subtilis. | Several Bacillus subtilis W-23 auxotrophs were unable to produce wild-type pigment normally on minimal agars supplemented sufficiently for growth. This offers a reliable means for scoring genotypes. | ['Agar', 'Amino Acids', 'Bacillus subtilis', 'Genetics, Microbial', 'Genotype', 'Mutation', 'Pigments, Biological', 'Transduction, Genetic'] | 4,988,046 | [['D09.698.360.041'], ['D12.125'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['H01.158.273.343.330', 'H01.158.273.540.367'], ['G05.380'], ['G05.365.590'], ['D23.767'], ['E05.393.350.800', 'G05.728.850']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Isotopic findings in anomalous origin of the left coronary artery from the pulmonary artery: report of an adult case. | Anomalous origin of the left coronary artery from the main pulmonary trunk results in myocardial ischemia or infarction, and may be a cause of death in the first months of life. Some patients, however, develop satisfactory coronary collateral circulation and remain asymptomatic into adulthood. In these patients, myocar... | ['Adolescent', 'Coronary Vessel Anomalies', 'Erythrocytes', 'Female', 'Gated Blood-Pool Imaging', 'Heart Defects, Congenital', 'Humans', 'Pulmonary Artery', 'Syndrome', 'Technetium', 'Thallium Radioisotopes', 'Tomography, Emission-Computed, Single-Photon'] | 1,880,581 | [['M01.060.057'], ['C14.240.400.210', 'C14.280.400.210', 'C16.131.240.400.210'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['E01.370.350.130.500.750', 'E01.370.350.130.937.350', 'E01.370.350.710.715.710.350', 'E01.370.370.050.650.650.350', 'E01.370.370.380.710.350', 'E01.370.384.730.715.710.350'], ['C14.240.40... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A comparative analysis of the transcriptome profiles of liver and muscle tissue in pigs divergent for feed efficiency. | BACKGROUND: The improvement of feed efficiency is a key economic goal within the pig production industry. The objective of this study was to examine transcriptomic differences in both the liver and muscle of pigs divergent for feed efficiency, thus improving our understanding of the molecular mechanisms influencing fee... | ['Animals', 'Eating', 'Liver', 'Muscles', 'Swine', 'Transcriptome'] | 31,170,913 | [['B01.050'], ['G07.203.650.283', 'G10.261.330'], ['A03.620'], ['A02.633', 'A10.690'], ['B01.050.150.900.649.313.500.880'], ['G02.111.873.750', 'G05.297.700.750', 'G05.360.920']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Silencing GhNDR1 and GhMKK2 compromises cotton resistance to Verticillium wilt. | Cotton is an important cash crop worldwide, and is a significant source of fiber, feed, foodstuff, oil and biofuel products. Considerable effort has been expended to increase sustainable yield and quality through molecular breeding and genetic engineering of new cotton cultivars. Given the recent availability of the wh... | ['DNA, Plant', 'Gene Expression Regulation, Plant', 'Gene Silencing', 'Genes, Plant', 'Gossypium', 'Immunity, Innate', 'Mitogen-Activated Protein Kinase Kinases', 'Plant Diseases', 'Plant Proteins', 'Protoplasts', 'Transcription Factors', 'Transfection', 'Verticillium'] | 21,219,508 | [['D13.444.308.435'], ['G05.308.375'], ['G05.308.203.374'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['B01.650.940.800.575.912.250.859.821.500.244'], ['G12.450.564'], ['D08.811.913.696.620.682.700.565', 'D08.811.913.696.620.682.725.200', 'D12.644.360.440', 'D12.776.476.440'], ['G15.610'], ['D12.776.765'], ['... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Negative-FLAIR vascular hyperintensities serve as a marker of no recanalization during hospitalization in acute stroke. | BACKGROUND: Since acute fluid-attenuated inversion recovery vascular hyperintensity (FVH) is indicative of disordered blood flow, FVH is considered a marker of acute major arterial occlusion. Conversely, the role of the absence of FVH (negative-FVH) remains unknown.METHODS: Consecutive stroke patients were studied via ... | ['Aged', 'Aged, 80 and over', 'Arterial Occlusive Diseases', 'Female', 'Humans', 'Magnetic Resonance Angiography', 'Male', 'Middle Aged', 'Stroke'] | 31,836,384 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.137'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500.500', 'E01.370.370.050.500'], ['M01.060.116.630'], ['C10.228.140.300.775', 'C14.907.253.855']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of sodium hydroxide exposure on esophageal epithelial cells in an in vitro ovine model: implications for esophagus tissue engineering. | BACKGROUND: Esophagus tissue engineering holds promises for esophageal replacement after severe caustic injuries. The aim of this study was to determine whether viable esophageal epithelial cells could be isolated from an esophagus exposed to varying concentrations of alkali with regard to number, viability, and morpho... | ['Animals', 'Biopsy', 'Caustics', 'Cell Count', 'Cell Survival', 'Cells, Cultured', 'Dose-Response Relationship, Drug', 'Epithelial Cells', 'Esophagus', 'Sheep', 'Sodium Hydroxide', 'Tissue Engineering'] | 22,595,564 | [['B01.050'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D27.720.185', 'D27.888.569.185'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.346'], ['A11.251'], ['G07.690.773.875', 'G07.690.93... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. | AIM: The present study evaluated the possibility of drug interactions involving blueberry juice (BBJ) and substrate drugs whose clearance is dependent on cytochromes P4503A (CYP3A) and P4502C9 (CYP2C9).METHODS: A 50:50 mixture of lowbush and highbush BBJ was evaluated in vitro as an inhibitor of CYP3A activity (hydroxy... | ['Adult', 'Anthocyanins', 'Aryl Hydrocarbon Hydroxylases', 'Beverages', 'Blueberry Plants', 'Buspirone', 'Citrus paradisi', 'Cytochrome P-450 CYP2C9', 'Cytochrome P-450 CYP3A', 'Cytochrome P-450 CYP3A Inhibitors', 'Drug Interactions', 'Female', 'Fluconazole', 'Flurbiprofen', 'Food-Drug Interactions', 'Furocoumarins', '... | 22,943,633 | [['M01.060.116'], ['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['G07.203.100', 'J02.200'], ['B01.650.940.800.575.912.250.341.937.774.249'], ['D02.455.426.779.120', 'D03.383.606.210', 'D03.383.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Age dependence of serum beta-N-acetylhexosaminidase (NAG) activity. | Serum N-acetyl-beta-D-glucosaminidase (NAG; EC 3.2.1.30) is a hexosaminidase and may be a predictor of vascular injury, e.g., in infant respiratory distress syndrome, pneumonia, broncho-pulmonary dysplasia and necrotizing enterocolitis. To estimate the new diagnostic prospects we have modified our urinary NAG assay. In... | ['Acetylglucosamine', 'Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Catalysis', 'Child', 'Child, Preschool', 'Clinical Enzyme Tests', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged', 'Reference Values', 'Spectrum Analysis', 'Statistical Distributions', 'Thiazoles', 'beta-N-A... | 15,080,564 | [['D09.067.342.531.050'], ['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G02.130'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.225.124.200', 'E05.196.427.200', 'E05.200.124.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.7... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
ROCK-1 mediates diabetes-induced retinal pigment epithelial and endothelial cell blebbing: Contribution to diabetic retinopathy. | In diabetic retinopathy, the exact mechanisms leading to retinal capillary closure and to retinal barriers breakdown remain imperfectly understood. Rho-associated kinase (ROCK), an effector of the small GTPase Rho, involved in cytoskeleton dynamic regulation and cell polarity is activated by hyperglycemia. In one year-... | ['1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine', 'Aged', 'Animals', 'Biomarkers', 'Case-Control Studies', 'Cytoskeleton', 'Diabetes Mellitus, Experimental', 'Diabetes Mellitus, Type 2', 'Diabetic Retinopathy', 'Disease Models, Animal', 'Endothelial Cells', 'Female', 'Fluorescent Antibody Technique', 'Humans', 'Hypoxia... | 28,821,742 | [['D02.886.590.700.545', 'D03.383.606.527', 'D03.633.100.531.400'], ['M01.060.116.100'], ['B01.050'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A11.284.430.214.190.750'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C18.452.394.750.149', 'C19.246.300']... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Fluorometric detection of silver(I) using cytosine-Ag(I)-cytosine pair formation, DNA assembly and the AND logic operation of a multiple-component DNAzyme. | A nonenzymatic fluorometric assay is described for highly sensitive and selective detection of silver ion. It is making use of a controlled DNA assembly and an AND logic operation of a multiple-component DNAzyme (MNAzyme). It corresponds to an Ag(I)-responsive three-way junction (3-WJ) assembly. The tailored probes of ... | ['Biosensing Techniques', 'Cytosine', 'DNA, Catalytic', 'Drinking Water', 'Fluorescence', 'Fluorometry', 'Limit of Detection', 'Logic', 'Rivers', 'Silver', 'Water Pollutants, Chemical'] | 31,292,764 | [['E05.601.043'], ['D03.383.742.698.421'], ['D08.811.165', 'D08.811.913.696.445.735.265', 'D13.444.308.243'], ['D01.045.250.875.300', 'D01.248.497.158.459.650.300', 'D01.650.550.925.199', 'G07.203.100.418', 'J02.200.418'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['E05.196.712.516.600'], ['E05.318.740.87... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Humanities [K]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The surgical treatment of bronchial carcinoid adenoma: a personal experience. | Clinical and pathological observations on 7 resected cases of bronchial carcinoid have been reviewed. Bronchoscopy was the most definitive diagnostic procedure. Bronchoplastic procedures were the treatment of choice for these low-grade potentially malignant lesions. Indications for extensive lung resection were distal ... | ['Adult', 'Bronchial Neoplasms', 'Carcinoid Tumor', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Prognosis'] | 6,671,894 | [['M01.060.116'], ['C04.588.894.797.520.109', 'C08.127.265', 'C08.785.520.100'], ['C04.557.465.625.650.200', 'C04.557.470.200.025.200', 'C04.557.580.625.650.200'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.63... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Natural history of lesions with the MR imaging appearance of multinodular and vacuolating neuronal tumor. | PURPOSE: Multinodular and vacuolating neuronal tumor (MVNT) have been recently added to the WHO classification of CNS tumors and has not been extensively reported upon in the radiological literature. We report the first radiological and the largest series of cases, aiming to highlight the natural history of lesions wit... | ['Adult', 'Brain Neoplasms', 'Diagnosis, Differential', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neoplasms, Neuroepithelial', 'Retrospective Studies'] | 28,752,311 | [['M01.060.116'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C04.557.465.625.600', 'C04.557.470.670', 'C04.557.580.625.600'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Real-time orthogonal mode scanning of the heart. I. System design. | A necessary percursor to real-time three-dimensional echocardiographic imaging is the ability to obtain multiple planes of acoustic data simultaneously. A new ultrasound imaging technique facilitates the display of two real-time orthogonal B-mode images (O-mode). The O-mode technique uses a novel two-dimensional transd... | ['Adult', 'Aged', 'Echocardiography', 'Equipment Design', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pericardial Effusion'] | 3,711,484 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.695']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mutation analysis in spinal muscular atrophy using allele-specific polymerase chain reaction. | Polymerase chain reaction (PCR), followed by restriction digestion is universally used for molecular diagnosis of spinal muscular atrophy (SMA). In the present study, we have used a modified strategy based on amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) to develop a rapid and reliable m... | ['Alleles', 'DNA Mutational Analysis', 'Female', 'Humans', 'Muscular Atrophy, Spinal', 'Polymerase Chain Reaction', 'Pregnancy', 'Prenatal Diagnosis'] | 22,900,372 | [['G05.360.340.024.340.030'], ['E05.393.760.700.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.854.468', 'C10.574.562.500', 'C10.668.467.500'], ['E05.393.620.500'], ['G08.686.784.769'], ['E01.370.378.630']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical prediction score for identifying patients with pulmonary veno-occlusive disease/pulmonary capillary hemangiomatosis. | BACKGROUND: Pulmonary veno-occlusive disease (PVOD) and pulmonary capillary hemangiomatosis (PCH) are rare causes of pulmonary hypertension. Although diagnosis is based on pathological findings, an early diagnosis is crucial because of poor prognosis compared to other types of pulmonary hypertension. Furthermore, vasod... | ['Adult', 'Area Under Curve', 'Early Diagnosis', 'Female', 'Hemangioma, Capillary', 'Humans', 'Hypertension, Pulmonary', 'Lung', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Pulmonary Artery', 'Pulmonary Edema', 'Pulmonary Veno-Occlusive Disease', 'Sensitivity and Specificity', 'Smoking', 'Tom... | 29,548,663 | [['M01.060.116'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['E01.390'], ['C04.557.645.375.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['A04.411'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E05.318.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
EIF3D silencing suppresses renal cell carcinoma tumorigenesis via inducing G2/M arrest through downregulation of Cyclin B1/CDK1 signaling. | There are no effective therapies for advanced renal cell carcinoma (RCC), except for VEGFR inhibitors with only ~50% response rate. To identify novel targets and biomarkers for RCC is of great importance in treating RCC. In this study, we observed that eukaryotic initiation factor 3d (EIF3D) expression was significantl... | ['CDC2 Protein Kinase', 'Carcinoma, Renal Cell', 'Cell Line, Tumor', 'Cell Proliferation', 'Cyclin B1', 'Cyclin-Dependent Kinases', 'Eukaryotic Initiation Factor-3', 'G2 Phase Cell Cycle Checkpoints', 'Gene Expression Regulation, Neoplastic', 'Gene Silencing', 'Humans', 'Kidney Neoplasms', 'Neoplasm Staging', 'RNA Inte... | 27,035,563 | [['D08.811.913.696.620.682.700.646.500.500.250', 'D08.811.913.696.620.682.700.646.500.984.500', 'D12.644.360.250.067.249', 'D12.644.360.250.580.500', 'D12.776.167.200.067.249', 'D12.776.167.200.580.500', 'D12.776.476.250.067.249', 'D12.776.476.250.580.500', 'D12.776.744.360'], ['C04.557.470.200.025.390', 'C04.588.945.9... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Temporal variation in bacterial disease frequency: molecular population genetic analysis of scarlet fever epidemics in Ottawa and in eastern Germany. | In an effort to understand the molecular genetic basis of temporal variation in frequency and severity of bacterial disease, genetic relationships among strains of Streptococcus pyogenes that caused scarlet fever epidemics in Canada in the early 1940s and in eastern Germany in the 1960s to 1980s were studied. Applicati... | ['Alleles', 'Bacterial Proteins', 'Disease Outbreaks', 'Electrophoresis', 'Exotoxins', 'Germany, East', 'Humans', 'Membrane Proteins', 'Ontario', 'Pyrogens', 'Scarlet Fever', 'Streptococcus pyogenes', 'Time Factors'] | 8,440,944 | [['G05.360.340.024.340.030'], ['D12.776.097'], ['N06.850.290'], ['E05.196.401', 'E05.301.300'], ['D23.946.350'], ['Z01.586.338'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543'], ['Z01.107.567.176.639'], ['D27.888.569.673'], ['C01.150.252.410.890.823'], ['B03.353.750.737.872.575', 'B03.510.400.800.872.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Epigenetic modifications in cutaneous malignant melanoma: EZH2, H3K4me2, and H3K27me3 immunohistochemical expression is enhanced at the invasion front of the tumor. | Cancer stem cells and the misregulation of epigenetic modifications have been identified to possess a determinative role in carcinogenesis. The purpose of this study was to investigate the expression profile of EZH2 and H3K4me2 and H3K27me3, which constitute stem cell-like "bivalent" domains, in cutaneous malignant mel... | ['Adult', 'Aged', 'Biomarkers, Tumor', 'Enhancer of Zeste Homolog 2 Protein', 'Epigenesis, Genetic', 'Female', 'Histones', 'Humans', 'Immunohistochemistry', 'Male', 'Melanoma', 'Methylation', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplastic Stem Cells', 'Polycomb Repressive Complex 2', 'Predictive Value of Tests', '... | 25,614,949 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['D05.500.781.750.250', 'D08.811.913.555.500.800.200.500.500.500', 'D12.776.660.235.600.200.250', 'D12.776.664.235.800.200.250', 'D12.776.930.780.890.200.250'], ['G05.308.203'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Dissolution behavior and in vitro evaluation of sputtered hydroxyapatite films subject to a low temperature hydrothermal treatment. | Hydroxyapatite (HA) was coated onto titanium substrates using radio frequency sputtering. Some of the as-sputtered films were hydrothermally recrystallized at 110 degrees C. In immersion tests, the as-sputtered film completely dissolved after 2 days in a culture medium, whereas the thickness of hydrothermally treated f... | ['Animals', 'Cell Proliferation', 'Coated Materials, Biocompatible', 'Crystallization', 'Durapatite', 'Hot Temperature', 'Materials Testing', 'Mice', 'Microscopy, Electron, Scanning', 'Osteoblasts', 'Prostheses and Implants', 'Surface Properties', 'Titanium'] | 16,278,871 | [['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['D25.130.420', 'J01.637.051.130.420'], ['E05.196.300', 'G02.171'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Inducible proteinase of Candida albicans in diagnostic serology and in the pathogenesis of systemic candidosis. | The extracellular acid proteinase of Candida albicans was purified from culture filtrates by a single-column chromatographic step. The purity of the enzyme and its unique antigenic properties were confirmed by polyacrylamide-gel electrophoresis and by reaction with homologous and heterologous anti-sera. The purified en... | ['Animals', 'Candida albicans', 'Candidiasis', 'Endopeptidases', 'Enzyme Induction', 'Fluorescent Antibody Technique', 'Humans', 'Rabbits', 'Serologic Tests'] | 6,997,486 | [['B01.050'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['C01.150.703.160'], ['D08.811.277.656.300'], ['G05.308.320.200'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comparison of the efficacy of cetirizine and terfenadine. A double-blind, controlled study of chronic idiopathic urticaria. | In a 20-d, double-blind, randomized, parallel study, the efficacy of cetirizine and terfenadine was compared in 30 patients with chronic idiopathic urticaria. Subjects were randomly divided into two 15-patient groups. The first group was given cetirizine (10 mg once daily); the second terfenadine (60 mg twice daily). C... | ['Adult', 'Cetirizine', 'Chronic Disease', 'Double-Blind Method', 'Humans', 'Terfenadine', 'Urticaria'] | 8,368,464 | [['M01.060.116'], ['D03.383.606.515.200'], ['C23.550.291.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.389.115.800', 'D03.383.621.855'], ['C17.800.862.945', 'C20.543.480.904']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Methylbromide intoxication: a case report. | This work focuses on the neurophysiological features in a patient with action myoclonus and mental deterioration following methylbromide intoxication. The patient is a 28-year-old man, without respiratory distress or exposure to other toxics. Myoclonus improved with polytherapy (clonazepam, 5-HT, carbidopa, GABA). The ... | ['Adult', 'Carbidopa', 'Clonazepam', 'Drug Therapy, Combination', 'Electroencephalography', 'Epilepsies, Myoclonic', 'Epilepsy, Tonic-Clonic', 'Evoked Potentials', 'Humans', 'Hydrocarbons, Brominated', 'Male', 'Myoclonus', 'Reaction Time', 'Substance-Related Disorders'] | 1,373,251 | [['M01.060.116'], ['D02.092.311.200.538.200', 'D02.442.200', 'D02.455.426.559.389.657.166.175.200.538.200'], ['D03.633.100.079.080.070.150'], ['E02.319.310'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.375.130', 'C10.228.140.490.493.063'], ['C10.228.140.490.375.290'], ['G07.265.216.500', 'G11.561.200.500... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[In vitro emergence of ertapenem resistance in Escherichia coli producing extended-spectrum â-lactamase]. | INTRODUCTION: The occurrence of community-associated infections due to extended-spectrum â-lactamase (ESBL)-producing Escherichia coli is increasing worldwide. These organisms are frequently resistant to many of the antimicrobial agents but remain susceptible to carbapenems. We investigated the in vitro emergence of ca... | ['Anti-Bacterial Agents', 'Drug Resistance, Bacterial', 'Ertapenem', 'Escherichia coli', 'Escherichia coli Infections', 'Imipenem', 'Meropenem', 'Microbial Sensitivity Tests', 'Mutation', 'Thienamycins', 'beta-Lactamases', 'beta-Lactams'] | 24,676,243 | [['D27.505.954.122.085'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['D02.065.589.099.124.225', 'D03.633.100.300.124.225'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['D02.065.589.099.124.300.500', 'D03.633.100.300.124.300.500'], ['D02.065.589.099.124.300.750'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nitric oxide increases the migratory activity of non-small cell lung cancer cells via AKT-mediated integrin áv and â1 upregulation. | BACKGROUND: Previously, nitric oxide (NO) has been found to affect the metastatic behavior of various types of cancer. In addition, it has been found that alterations in integrin expression may have profound effects on cancer cell survival and migration. Here, we aimed at assessing the effects of non-toxic concentratio... | ['Blotting, Western', 'Carcinoma, Non-Small-Cell Lung', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Cell Survival', 'Humans', 'Integrin alphaV', 'Integrin beta1', 'Lung Neoplasms', 'Nitric Oxide', 'Proto-Oncogene Proteins c-akt', 'Up-Regulation'] | 27,376,838 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['B01.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Abnormal conformation and impaired degradation of propylthiouracil-induced neutrophil extracellular traps: implications of disordered neutrophil extracellular traps in a rat model of myeloperoxidase antineutrophil cytoplasmic antibody-associated vasculitis. | OBJECTIVE: Neutrophil extracellular traps (NETs) are composed of DNA and antimicrobial proteins, including myeloperoxidase (MPO). Recent studies have demonstrated that impaired regulation of NETs could trigger an autoimmune response. Propylthiouracil (PTU), an antithyroid drug, is associated with a risk of MPO antineut... | ['Animals', 'Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis', 'Antimetabolites', 'Carcinogens', 'DNA', 'Deoxyribonuclease I', 'Disease Models, Animal', 'Humans', 'Neutrophils', 'Nucleic Acid Conformation', 'Peroxidase', 'Propylthiouracil', 'Rats', 'Rats, Inbred WKY', 'Tetradecanoylphorbol Acetate', 'alpha-D... | 22,777,766 | [['B01.050'], ['C14.907.940.897.249', 'C20.111.193'], ['D27.505.519.186', 'D27.888.569.042'], ['D27.888.569.100'], ['D13.444.308'], ['D08.811.277.352.335.350.250'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', '... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A knee-specific finite element analysis of the human anterior cruciate ligament impingement against the femoral intercondylar notch. | This work presents a finite element analysis of anterior cruciate ligament (ACL) impingement against the intercondylar notch during tibial external rotation and abduction, as a mechanism of noncontact ACL injuries. Experimentally, ACL impingement was measured in a cadaveric knee in terms of impingement contact pressure... | ['Anterior Cruciate Ligament', 'Anterior Cruciate Ligament Injuries', 'Biomechanical Phenomena', 'Femur', 'Finite Element Analysis', 'Humans', 'Knee', 'Stress, Mechanical'] | 20,413,123 | [['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['C26.558.554.213'], ['G01.154.090', 'G01.374.089'], ['A02.835.232.043.150'], ['E05.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.450'], ['G01.374.835']] | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of ecological doses of the most widespread phthalate on a terrestrial species, the ant Lasius niger. | Phthalates are synthetic contaminants released into the environment notably by plastic waste. Semi-volatile, they adsorb to atmospheric particles and get distributed in all ecosystems. Effects of this major anthropogenic pollution in economical species in aquatic habitats have attracted large interest. On the contrary,... | ['Animals', 'Ants', 'Diethylhexyl Phthalate', 'Environmental Pollutants', 'Feeding Behavior', 'Gene Expression', 'Oviparity', 'Oxidative Stress'] | 24,713,390 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.205'], ['D02.241.223.805.250'], ['D27.888.284'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['G05.297'], ['G08.686.650'], ['G03.673', 'G07.775.750']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Age and cohort rise in diabetes prevalence among older Australian women: Case ascertainment using survey and healthcare administrative data. | BACKGROUND: Due to the absence and or costliness of biological measures such as glycated haemoglobin, diabetes case ascertainment and prevalence studies are usually conducted using surveys or routine health service use databases. However, the use of each of these sources is associated with its limitations potentially i... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Australia', 'Cohort Studies', 'Diabetes Complications', 'Diabetes Mellitus', 'Exercise', 'Female', 'Health Surveys', 'Humans', 'Middle Aged', 'Obesity', 'Prevalence', "Women's Health"] | 32,555,738 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.639.100', 'Z01.678.100.373'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C19.246.099'], ['C18.452.394.750', 'C19.246'], ['G11.427.410.698.277', 'I03.350'], ['E05.318.308.980.438', 'N05.715.... | ['Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Congenital nephrotic syndrome, an uncommon presentation of cytomegalovirus infection. | Cytomegalovirus (CMV) infection is a very rare infection in children as well as in infancy. In CMV infection extra renal manifestations in central nervous system (CNS), eyes and hematological are prominent and common than renal manifestation. We are describing two case reports one at the age of 5 months and another at ... | ['Cytomegalovirus Infections', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Hypothyroidism', 'Immunoglobulin M', 'Infant', 'Infant, Newborn', 'Nephrotic Syndrome'] | 18,626,461 | [['C01.925.256.466.245'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.482'], ['D12.776.124.486.485.114.619.574', 'D12.776.124.790.651.114.619.574', 'D12.776.377.715.548.114.619.574'], ['M0... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Automating digital leaf measurement: the tooth, the whole tooth, and nothing but the tooth. | Many species of plants produce leaves with distinct teeth around their margins. The presence and nature of these teeth can often help botanists to identify species. Moreover, it has long been known that more species native to colder regions have teeth than species native to warmer regions. It has therefore been suggest... | ['Algorithms', 'Image Processing, Computer-Assisted', 'Plant Leaves', 'Tilia'] | 22,870,286 | [['G17.035', 'L01.224.050'], ['L01.224.308'], ['A18.024.812'], ['B01.650.940.800.575.912.250.859.821.500.944']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Erysiphe abbreviata on cherry bark oak--morphology, phylogeny and taxonomy. | Powdery mildew on cherry bark oak (Quercus falcate var. pagodifolia) collected in Tennessee, USA, was determined to be Erysiphe abbreviata, a species confined to North America. The diagnostically important anamorph of this species is described for the first time. Sequence analyses of the rDNA ITS region and D1/D2 domai... | ['Ascomycota', 'Base Sequence', 'DNA, Fungal', 'DNA, Ribosomal Spacer', 'Molecular Sequence Data', 'Phylogeny', 'Plant Diseases', 'Polymerase Chain Reaction', 'Quercus', 'RNA, Ribosomal, 28S', 'Sequence Alignment', 'Sequence Analysis, DNA'] | 18,268,900 | [['B01.300.107'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.300'], ['D13.444.308.324.230', 'D13.444.308.475.230'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G15.610'], ['E05.393.620.500'], ['B01.650.940.800.575.912.250.859.750.300.500'], ['D13.444.735.686.690'], ['... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Recent demography drives changes in linked selection across the maize genome. | Genetic diversity is shaped by the interaction of drift and selection, but the details of this interaction are not well understood. The impact of genetic drift in a population is largely determined by its demographic history, typically summarized by its long-term effective population size (Ne). Rapidly changing populat... | ['Crops, Agricultural', 'Domestication', 'Evolution, Molecular', 'Genome, Plant', 'Selection, Genetic', 'Whole Genome Sequencing', 'Zea mays'] | 27,294,617 | [['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['J01.040.330'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.365'], ['G05.783'], ['E05.393.760.700.825'], ['B01.650.940.800.575.912.250.822.966']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Changes in the synthesis, distribution and sulphation of glycosaminoglycans of cultured human skin fibroblasts upon ascorbate feeding. | The effect of ascorbic acid on the synthesis, distribution and sulphation of glycosaminoglycans by human skin fibroblasts has been examined. Medium was supplemented with ascorbate over several days, and cultures incubated with [3H]glucosamine and Na2(35)SO4 for 48 h, followed by analysis of the glycosaminoglycans in th... | ['Ascorbic Acid', 'Cells, Cultured', 'Chondroitin Sulfates', 'Dermatan Sulfate', 'Fibroblasts', 'Glycosaminoglycans', 'Heparitin Sulfate', 'Humans', 'Hyaluronic Acid', 'Skin', 'Tissue Distribution'] | 6,420,422 | [['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['A11.251'], ['D09.698.373.200.300'], ['D09.698.373.200.380'], ['A11.329.228'], ['D09.698.373'], ['D09.698.373.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.475'], ['A17.815'], ['G03.787.917', 'G07.690.725.949']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A multicentre in vitro evaluation of piperacillin/tazobactam in Germany. | In a multicentre study in Germany 10584 fresh clinical aerobic isolates were tested for susceptibility to piperacillin (30 micrograms or 100 micrograms discs) and piperacillin/tazobactam (30 micrograms/10 micrograms or 100 micrograms/10 micrograms discs). Preliminary breakpoints for piperacillin/tazobactam according to... | ['Drug Therapy, Combination', 'Enterobacteriaceae', 'Germany', 'Gram-Negative Bacteria', 'Gram-Positive Bacteria', 'Humans', 'Microbial Sensitivity Tests', 'Penicillanic Acid', 'Piperacillin', 'Tazobactam', 'beta-Lactamase Inhibitors'] | 7,524,792 | [['E02.319.310'], ['B03.440.450.425', 'B03.660.250.150'], ['Z01.542.315'], ['B03.440'], ['B03.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D02.065.589.099.750.687', 'D02.886.108.750.687', 'D03.633.100.300.750.687'], ['D02.065.589.099.750.750.05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Detection of an aortoenteric fistula in a patient with intermittent bleeding. | BACKGROUND: A 57-year-old male with an aortobifemoral bypass graft presented to a gastroenterology clinic with a 3-month history of intermittent hematemesis, melena and fever. The patient had received antibiotic therapy 2 months before for the same symptoms; however, following brief regression ( approximately 3 weeks) ... | ['Aortic Diseases', 'Blood Vessel Prosthesis Implantation', 'Hematemesis', 'Humans', 'Intestinal Fistula', 'Male', 'Melena', 'Middle Aged', 'Treatment Outcome', 'Vascular Fistula'] | 18,332,903 | [['C14.907.109'], ['E04.100.814.868.500', 'E04.650.200'], ['C06.405.227.400', 'C23.550.414.788.400', 'C23.888.821.937.019'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.267.550', 'C06.405.469.471', 'C23.300.575.185.550'], ['A12.459.764', 'C06.405.227.600', 'C23.550.414.788.600'], ['M01.060.116.630'], ['E01.7... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The relationship between isthmic and degenerative spondylolisthesis and the configuration of the lamina and facet joints. | Advanced degenerative change in the facet joints leads to displacement of the vertebral body, and the configuration of facet joints and lamina is closely related to the development of degenerative spondylolisthesis. For this study 103 patients and 25 controls were examined with respect to the configuration of the lamin... | ['Adult', 'Aged', 'Case-Control Studies', 'Female', 'Humans', 'Intervertebral Disc', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Spondylolisthesis', 'Tomography, X-Ray Computed'] | 7,552,647 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.165.308.410', 'A02.835.232.834.432', 'A10.165.382.350.050'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['C05.116.900.938.500.500'], ['E01.370.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Effects of chronic hypoxia on microcirculation of the central nervous system during embryonic development]. | In the attempt to know the factors influencing the vasculogenesis and to verify whether the vessel formation and growth are influenced, during different ontogenetic periods, by oxygen deficiency, the intraneural vascular network has been morphometrically analyzed in chicken embryo optic tectum under conditions of aerog... | ['Animals', 'Chick Embryo', 'Hypoxia', 'Microcirculation', 'Superior Colliculi', 'Time Factors'] | 6,704,252 | [['B01.050'], ['A13.350.150', 'A16.331.200'], ['C23.888.852.079'], ['G09.330.100.645'], ['A08.186.211.132.659.800.816'], ['G01.910.857']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Haemodynamic response to abdominal decompression in acute Budd-Chiari syndrome. | BACKGROUND: Intra-abdominal hypertension (IAH) and abdominal compartment syndrome commonly occur in patients with liver disease.AIMS: We compared haemodynamic variables pre- and post-abdominal decompression in patients with acute Budd-Chiari syndrome (BCS) and patients with chronic liver disease (CLD), ascites and IAH.... | ['Acute Disease', 'Adult', 'Aged', 'Ascites', 'Blood Volume', 'Budd-Chiari Syndrome', 'Cardiac Output', 'Central Venous Pressure', 'Decompression, Surgical', 'End Stage Liver Disease', 'Female', 'Hemodynamics', 'Humans', 'Hypovolemia', 'Intra-Abdominal Hypertension', 'Liver Transplantation', 'London', 'Male', 'Middle A... | 21,745,299 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['C23.550.081'], ['G09.188.130', 'G09.330.380.092'], ['C06.552.347', 'C14.907.355.830.925.275'], ['E01.370.370.380.150', 'G09.330.380.124'], ['G09.330.380.076.732.336'], ['E04.188'], ['C06.552.308.500.177'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.1... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Analysis of 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB)-releasing DNA adducts in human exfoliated oral mucosa cells by liquid chromatography-electrospray ionization-tandem mass spectrometry. | Quantitation of DNA adducts could provide critical information on the relationship between exposure to tobacco smoke and cancer risk in smokers. In this study, we developed a robust and sensitive liquid chromatography-tandem mass spectrometry method for the analysis of 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB)-releasing... | ['Biomarkers', 'Butanones', 'Chromatography, High Pressure Liquid', 'DNA', 'DNA Adducts', 'Humans', 'Mouth Mucosa', 'Mouthwashes', 'Nitrosamines', 'Pyridines', 'Smoking', 'Solid Phase Extraction', 'Spectrometry, Mass, Electrospray Ionization'] | 23,252,610 | [['D23.101'], ['D02.522.296'], ['E05.196.181.400.300'], ['D13.444.308'], ['D13.444.308.135', 'G05.200.104'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.615.550.599', 'A14.549.512'], ['D25.583', 'D27.720.102.583', 'D27.720.269.583', 'J01.637.051.583'], ['D02.654.442'], ['D03.383.725'], ['F01.145.805'], ['E05... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Evaluation of a bench-top nephelometric immunoassay analyzer. | We evaluated the Technicon DPA-1 immunoassay analyzer on its analytical characteristics. Therefore we studied three assays: albumin in cerebrospinal fluid and IgG and transferrin in serum. When tested with the Cusum test for linearity albumin, IgG, and transferrin measurements showed no deviation from linearity. Closer... | ['Albumins', 'Evaluation Studies as Topic', 'Humans', 'Immunoassay', 'Immunoglobulin G', 'Nephelometry and Turbidimetry', 'Proteins', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Transferrin'] | 1,999,760 | [['D12.776.034'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['E05.196.712.650'], ['D12.776'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Intramuscular progesterone versus 8% Crinone vaginal gel for luteal phase support for day 3 cryopreserved embryo transfer. | OBJECTIVE: To compare outcomes after intramuscular progesterone (IMP) or 8% Crinone vaginal gel for luteal support for day 3 cryopreserved embryo transfer (CET).DESIGN: Retrospective cohort study with multivariable analysis.SETTING: Academic medical center.PATIENT(S): All autologous and donor egg in vitro fertilization... | ['Adult', 'Cryopreservation', 'Embryo Transfer', 'Female', 'Humans', 'Injections, Intramuscular', 'Luteal Phase', 'Ovulation Induction', 'Pregnancy', 'Pregnancy Outcome', 'Progesterone', 'Treatment Outcome', 'Vaginal Creams, Foams, and Jellies'] | 22,959,457 | [['M01.060.116'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['E02.875.800.500', 'E05.820.800.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.460'], ['G08.686.605.410'], ['E02.875.800.984',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Haemostatic agent etamsylate in vitro and in vivo antagonizes anti-coagulant activity of heparin. | Etamsylate is indicated for several anti-hemorrhagic indications in human and veterinary medicine. However, etamsylate has been shown to be effective only in specific hemorrhagic situations. Furthermore, mechanism of action of etamsylate is not known but recent research has shown its ability to inhibit heparin binding ... | ['Animals', 'Anticoagulants', 'Dogs', 'Drug Antagonism', 'Ethamsylate', 'Female', 'Hemostatics', 'Heparin', 'Heparin Antagonists', 'Male', 'Rats, Sprague-Dawley', 'Vasodilation'] | 29,555,505 | [['B01.050'], ['D27.505.954.502.119'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.773.968.310'], ['D02.455.426.559.389.097.250', 'D02.886.645.600.080.050.100.300'], ['D27.505.954.502.270.463'], ['D09.698.373.400'], ['D27.505.519.452', 'D27.505.954.502.270.546'], ['B01.050.150.900.649.313.992.635.505.700.750... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sex-specific splicing and polyadenylation of dsx pre-mRNA requires a sequence that binds specifically to tra-2 protein in vitro. | Somatic sex determination in Drosophila involves a hierarchy of regulated alternative pre-mRNA processing. Female-specific splicing and/or polyadenylation of doublesex (dsx) pre-mRNA, the final gene in this pathway, requires transformer (tra) and transformer-2 (tra-2) proteins. The mechanisms by which these proteins re... | ['Animals', 'Base Sequence', 'Binding Sites', 'Cell Line', 'Cloning, Molecular', 'Drosophila', 'Drosophila Proteins', 'Exons', 'Female', 'Male', 'Molecular Sequence Data', 'Plasmids', 'Poly A', 'RNA Precursors', 'RNA Probes', 'RNA Splicing', 'RNA, Messenger', 'Repetitive Sequences, Nucleic Acid', 'Ribonucleoproteins', ... | 1,674,449 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['A11.251.210'], ['E05.393.220'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['G05.360.340.024.340.137.232'], ['L01.453.245.667'], ['G05.360.600'], ['D13.695.578.550.500'], ['D13.400.730', 'D13.4... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Leaching of nitrogen, phosphorus, TOC and COD from the biosolids of the municipal wastewater treatment plant of Thessaloniki. | Biosolids from the WWTP of Thessaloniki were examined for the leaching of phosphorus (as PO4(3-) -P), nitrogen (as NH4+ (-N) and NO3- (-N)), and organic matter (as TOC and COD), using two tests: (1) a pH static leaching test and (2) a characterization test, relating contaminant release to the liquid to solid (L/S) rati... | ['Aliivibrio fischeri', 'Greece', 'Nitrogen', 'Oxygen', 'Phosphorus', 'Sewage', 'Water Pollutants'] | 17,764,030 | [['B03.440.450.900.050.860', 'B03.660.250.830.050.860'], ['Z01.542.383'], ['D01.268.604', 'D01.362.625'], ['D01.268.185.550', 'D01.362.670'], ['D01.268.666'], ['D20.944.932.500'], ['D27.888.284.903']] | ['Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Behavioral considerations for engaging youth in HIV clinical research. | From both scientific and ethical perspectives, it is important that youth be enrolled in biomedical HIV prevention clinical trials. At the same time, adolescents, as minors, are considered a vulnerable population requiring particular attention to the reduction of potential harm associated with participation in such tri... | ['Adolescent', 'Adolescent Behavior', 'Adolescent Development', 'Biomedical Research', 'Clinical Trials as Topic', 'HIV Infections', 'Humans', 'Informed Consent', 'Risk Factors', 'Risk-Taking', 'Young Adult'] | 20,571,420 | [['M01.060.057'], ['F01.145.022'], ['F01.525.049', 'G07.345.374.500'], ['H01.770.644.145'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Association between dietary calcium and phosphorus intakes, dietary calcium/phosphorus ratio and bone mass in the Korean population. | BACKGROUND: Osteoporosis has become a major public health issue. Among various factors affected bone health, not only dietary calcium and phosphorus intakes, but also the dietary calcium/phosphorus ratio could relate to bone health. Therefore, we evaluated whether dietary calcium and phosphorus intakes, and dietary cal... | ['Adult', 'Age Factors', 'Bone Density', 'Calcium, Dietary', 'Cross-Sectional Studies', 'Female', 'Femur Neck', 'Humans', 'Lumbar Vertebrae', 'Male', 'Menopause', 'Middle Aged', 'Nutrition Surveys', 'Phosphorus, Dietary', 'Premenopause', 'Republic of Korea', 'Sex Factors'] | 25,496,564 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['G11.427.100'], ['D01.146.395'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['A02.835.232.043.150.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['G08.686.157.500', 'G08.686.841.249.500'], ['... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Use of propranolol in the treatment of idiopathic orthostatic hypotension. | Five patients with idiopathic orthostatic hypotension who had physiologic and biochemical evidence of severe autonomic dysfunction were included in the study. They all exhibited markedly reduced plasma catecholamines and plasma renin activity in both recumbent and upright positions and had marked hypersensitivity to th... | ['Aged', 'Blood Pressure', 'Catecholamines', 'Heart Rate', 'Humans', 'Hypotension, Orthostatic', 'Middle Aged', 'Norepinephrine', 'Posture', 'Propranolol', 'Renin'] | 611,664 | [['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.177.575.600.450', 'C14.907.514.482'], ['M01.060.116.630'], ['D02.033.100.291.502', 'D02.092.063.480', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multiple sclerosis: prospective analysis of TNF-alpha and 55 kDa TNF receptor in CSF and serum in correlation with clinical and MRI activity. | The possibility of antagonizing tumor necrosis factor-alpha (TNF-alpha) in vivo with antibodies or soluble TNF receptor has focused much interest on the role of this cytokine in the natural course of MS. We studied nine patients prospectively and serially for one year (14 time points, 131 observations). TNF-alpha and t... | ['Adult', 'Contrast Media', 'Disease Progression', 'Female', 'Gadolinium DTPA', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Methylprednisolone', 'Middle Aged', 'Multiple Sclerosis', 'Organometallic Compounds', 'Pentetic Acid', 'Prospective Studies', 'Receptors, Tumor Necrosis Factor', 'Recurrence', 'Tumor Necrosis... | 8,964,914 | [['M01.060.116'], ['D27.505.259.500', 'D27.720.259'], ['C23.550.291.656'], ['D02.092.782.590.401', 'D02.241.081.018.639.400', 'D02.257.141'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['D04.210.500.745.432.769.795.539'], ['M01.060.116.630'], ['C10.114.375.500', 'C10.314.350.500', 'C20.11... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
SLC26A7 can function as a chloride-loading mechanism in parietal cells. | To date three potential candidates for parietal cell basolateral Cl(-) entry have been described: the highly 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS)-sensitive Cl(-)/HCO(3)(-) exchanger AE2, the HCO(3)(-) and lowly DIDS-sensitive SLC26A7 protein, and the Na(+)-2Cl(-)K(+) cotransporter (NKCC1). In this ... | ["4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid", 'Animals', 'Antiporters', 'Chloride-Bicarbonate Antiporters', 'Chlorides', 'Fluorescent Antibody Technique', 'Gastric Acid', 'Gastric Mucosa', 'Image Processing, Computer-Assisted', 'In Vitro Techniques', 'Male', 'Oocytes', 'Parietal Cells, Gastric', 'Patch-Clamp Tec... | 17,404,755 | [['D02.455.426.559.389.150.700.200', 'D02.500.375.125', 'D02.886.250.125'], ['B01.050'], ['D12.776.157.530.450.162', 'D12.776.543.550.190', 'D12.776.543.585.450.162'], ['D12.776.157.530.450.162.193', 'D12.776.157.530.450.437.249', 'D12.776.157.530.937.656.249', 'D12.776.543.550.190.276', 'D12.776.543.550.779.249', 'D12... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of feeding green onions (Allium ascalonicum) to White Chinese geese (Threskiornis spinicollis). | Sudden increase in mortality was observed in 2 different flocks of mature breeder geese fed green onions. At necropsy, birds had pale epicardium with random petechiation, sanguinous fluid accumulation in the pericardial sac, and mild swelling of the liver and spleen. Histologically, there was accumulation of hemosideri... | ['Anemia', 'Animal Feed', 'Animals', 'Geese', 'Liver', 'Liver Diseases', 'Plants, Edible', 'Poisoning', 'Poultry Diseases', 'Shallots'] | 15,305,744 | [['C15.378.071'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.050.150.900.248.050.350', 'B01.050.150.900.248.690.492'], ['A03.620'], ['C06.552'], ['B01.650.510'], ['C25.723'], ['C22.131.728'], ['B01.650.940.800.575.912.250.618.100.050.060.800']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[The radiobiological aspects in the blocking of sensitive structures from the irradiation field]. | BACKGROUND: In some cases the total dose has to be reduced in a section of an irradiation field by means of a transmission block. This can be performed in 2 different ways: 1. A part of the planned fractions is blocked. 2. The dose of each fraction is reduced using a transmission block (transmission < 100%).METHOD: For... | ['Carcinoma, Bronchogenic', 'Carcinoma, Squamous Cell', 'Humans', 'Linear Models', 'Lung Neoplasms', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Patient Care Planning', 'Radiation Tolerance', 'Radiotherapy Dosage'] | 7,740,409 | [['C04.588.894.797.520.109.220', 'C08.381.540.140', 'C08.785.520.100.220'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', ... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of transnational migration on drug use: an ethnographic study of Nepali female heroin users in Hong Kong. | BACKGROUND: Past studies of female drug users in South Asia tend to focus on their plights, for instance, how they have been driven to drug use and encounter more problems than their male counterparts, such as HIV/AIDS and sexual abuse. Few studies focus on their active role--how they actively make use of resources in ... | ['Adolescent', 'Adult', 'Data Collection', 'Female', 'Grounded Theory', 'Heroin Dependence', 'Hong Kong', 'Humans', 'Nepal', 'Sexual Partners', 'Transients and Migrants', 'Young Adult'] | 25,060,613 | [['M01.060.057'], ['M01.060.116'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['H01.770.644.241.424'], ['C25.775.643.500.400', 'F03.900.647.500.300'], ['Z01.252.474.164.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.674'], ['M01.778'], ['M01.920'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Cadaveric anatomy of pelvic fracture urethral distraction injury: most injuries are distal to the external urinary sphincter. | PURPOSE: The anatomy of posterior urethral distraction injuries is controversial. We present a cadaver study of posterior urethral distraction injuries. To our knowledge this is the first study that establishes that the most common location is distal to the external urinary sphincter.MATERIALS AND METHODS: We performed... | ['Cadaver', 'Fractures, Bone', 'Humans', 'Male', 'Pelvic Bones', 'Urethra'] | 15,711,300 | [['C23.550.260.224'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043.825'], ['A05.360.444.492.726', 'A05.810.876']] | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Web-based training: readiness and perceptions of nurses. | This study was conducted as a descriptive study in order to determine the views of nurses working a university hospital on web-based training. Population consisted of all the nurses working in the hospital. It was found out that nurses use computer at the moderate level (46.5 %), they benefit from Internet at a good le... | ['Attitude of Health Personnel', 'Attitude to Computers', 'Computer Literacy', 'Computer-Assisted Instruction', 'Education, Distance', 'Education, Nursing', 'Educational Measurement', 'Internet', 'Nursing Staff, Hospital', 'Turkey'] | 25,160,169 | [['F01.100.050', 'N05.300.100'], ['F01.100.100'], ['L01.143.256'], ['I02.903.771.500.208'], ['I02.195'], ['I02.358.462'], ['I02.399'], ['L01.224.230.110.500'], ['M01.526.485.680.490', 'M01.526.485.740.523', 'N02.360.680.490', 'N02.360.740.523'], ['Z01.252.245.500.850']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Interaction of the vanadyl (IV) cation with carnosine and related ligands. | The interaction of the vanadyl (IV) (VO2+) cation with carnosine (the dipeptide beta-alanyl-histidine) has been investigated by electron absorption spectroscopy at high ligand-to-metal ratios and at different pH values. The results show that in the range 6.0-8.5, the cation interacts with the imidazole group of four di... | ['Carnosine', 'Glycylglycine', 'Histidine', 'Hydrogen-Ion Concentration', 'Imidazoles', 'Ligands', 'Magnetic Resonance Spectroscopy', 'Spectrophotometry', 'Vanadates'] | 8,971,356 | [['D12.644.400.100', 'D12.644.456.345.331', 'D12.776.631.650.100'], ['D12.644.456.345.575'], ['D12.125.072.329', 'D12.125.142.308'], ['G02.300'], ['D03.383.129.308'], ['D27.720.470.480'], ['E05.196.867.519'], ['E05.196.712.726', 'E05.196.867.826'], ['D01.248.497.158.952', 'D01.960.960']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interatrial shunt flow profiles in newborn infants: a colour flow and pulsed Doppler echocardiographic study. | Interatrial shunt flow profiles in 36 normal term infants were examined serially by colour flow and pulsed Doppler echocardiographic techniques from within an hour of birth to four or five days after birth. Shunt flow across the foramen ovale was detected in 33 normal infants (92%) within an hour of birth (mean 40 minu... | ['Blood Flow Velocity', 'Ductus Arteriosus', 'Echocardiography, Doppler', 'Heart Atria', 'Heart Septum', 'Humans', 'Infant, Newborn', 'Persistent Fetal Circulation Syndrome', 'Time Factors'] | 1,993,129 | [['E01.370.370.130', 'G09.330.380.630.080'], ['A07.541.278.395', 'A16.378.303.395'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['A07.541.358'], ['A07.541.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C08.381.423.694', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of genetic variability and mutation drift equilibrium of Banni buffalo using multi locus microsatellite markers. | The present study was conducted to evaluate genetic diversity of Banni buffalo and its relationship/differentiation with Murrah using genotypic data on 24 heterologus bovine specific microsatellite marker loci. A total of 138 alleles were observed with a mean of 5.75 alleles/locus across two populations. The mean obser... | ['Analysis of Variance', 'Animals', 'Buffaloes', 'Evolution, Molecular', 'Gene Frequency', 'Genetic Drift', 'Genetic Variation', 'Genetics, Population', 'Genotype', 'India', 'Mutation', 'Species Specificity'] | 19,130,283 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['B01.050.150.900.649.313.500.380.135'], ['G05.045.250', 'G16.075.250'], ['G05.330'], ['G05.045.300', 'G05.330.320'], ['G05.365'], ['H01.158.273.343.335'], ['G05.380'], ['Z01.252.245.393'], ['G05.365.590'], ['G16.824']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Morphological and molecular studies on life cycle stages of Diphtherostomum brusinae (Digenea: Zoogonidae) from northern Portugal. | Diphtherostomum brusinae was first recorded by the present study in the north of Portugal. Sporocysts, containing cercariae and encysted metacercariae, were observed in the gonads and digestive gland of the gastropod Nassarius reticulatus. Metacercariae were also found infecting the foot, mantle border and gills of the... | ['Animals', 'Cardiidae', 'DNA, Helminth', 'DNA, Ribosomal', 'Larva', 'Life Cycle Stages', 'Microscopy, Electron, Scanning', 'Portugal', 'Sequence Analysis, DNA', 'Trematoda', 'Trematode Infections'] | 19,265,558 | [['B01.050'], ['B01.050.500.644.080.150'], ['D13.444.308.315'], ['D13.444.308.475'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B05.500', 'G07.345.500.550.500'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['Z01.542.727'], ['E05.393.760.700'], ['B01.050.500.500.736.715'], ['C01.610.335.865']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Neo-tanshinlactone inspired synthesis, in vitro evaluation of novel substituted benzocoumarin derivatives as potent anti-breast cancer agents. | A small library of novel benzocoumarin derivatives based on naturally occurring neo-tanshinlactone scaffold was constructed and their antiproliferative activities against breast cancer cells MCF-7 and MDA-MB-231 were evaluated. A number of derivatives showed good anti-breast cancer activity, in some cases higher to tha... | ['Antineoplastic Agents', 'Apoptosis', 'Breast Neoplasms', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Proliferation', 'Coumarins', 'Female', 'Furans', 'Humans', 'Pyrones', 'Small Molecule Libraries'] | 20,951,035 | [['D27.505.954.248'], ['G04.146.954.035'], ['C04.588.180', 'C17.800.090.500'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D03.383.663.283.446', 'D03.633.100.150.446'], ['D03.383.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.663.718'], ['D27.720.470... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of dual pacemaker mechanisms in sinoatrial node discharge. | We investigated whether in the sinoatrial node (SAN) there are two different pacemaker mechanisms and whether either one can maintain spontaneous discharge. These questions were studied by means of an electrophysiological technique and of blockers of different diastolic currents in rabbit and guinea pig isolated SAN. I... | ['Action Potentials', 'Animals', 'Anti-Arrhythmia Agents', 'Barium Compounds', 'Cesium', 'Chlorides', 'Female', 'Guinea Pigs', 'Heart Rate', 'Indapamide', 'Isotonic Solutions', 'Male', 'Models, Biological', 'Myocardial Contraction', 'Piperidines', 'Potassium', 'Pyridines', 'Rabbits', 'Sinoatrial Node', 'Tetrodotoxin'] | 10,754,384 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['D27.505.954.411.097'], ['D01.103'], ['D01.268.549.125', 'D01.268.556.165', 'D01.552.528.160', 'D01.552.544.165'], ['D01.210.450.150', 'D01.248.497.158.215'], ['B01.050.150.900.649.313.992.550'], ['E01.370.600.875.500', 'G09.330.380.500'], ['D02.065.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biosynthesis and secretion of the third component of complement by human endothelial cells in vitro. | The third component of complement (C3) is synthesized and released by cultured human capillary endothelial cells. After the incubation of cells in a methionine-free medium containing 35S-methionine for 48 hr, culture supernatants were immunoprecipitated with anti-human C3 serum. SDS solubilization and 2-ME reduction of... | ['Antigens', 'Cells, Cultured', 'Child', 'Complement C3', 'Cycloheximide', 'Electrophoresis, Polyacrylamide Gel', 'Endothelium', 'Factor VIII', 'Fluorescent Antibody Technique', 'Humans', 'Male', 'von Willebrand Factor'] | 3,108,140 | [['D23.050'], ['A11.251'], ['M01.060.406'], ['D12.776.124.050.140', 'D12.776.124.486.274.250'], ['D03.383.621.808.240'], ['E05.196.401.402', 'E05.301.300.319'], ['A10.272.491'], ['D12.776.124.125.350', 'D12.776.811.286', 'D23.119.350'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Locus of control, life events and treatment outcome in alcohol dependent patients. | We investigated the relationship of locus of control and life events to outcome of treatment at 6 months in 67 patients with alcohol dependence. Outcome was less favourable in patients with pre-treatment scores indicating external locus of control than in those with internal locus of control. Furthermore, patients with... | ['Adult', 'Alcoholism', 'Female', 'Follow-Up Studies', 'Humans', 'Internal-External Control', 'Life Change Events', 'Male', 'Middle Aged', 'Prognosis', 'Recurrence'] | 3,176,993 | [['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['F01.829.458.410'], ['M01.060.116.630'], ['E01.789'], ['C23.550.291.937']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Correlation analysis between diabetic retinopathy and early atherosclerotic changes in adolescents with type 1 diabetes -- preliminary report]. | OBJECTIVE: Recent studies have shown a correlation between advanced diabetic retinopathy and late stages of atherosclerosis. There are no findings on a possible relation between diabetic retinopathy and diseases of the cardiovascular system at their earliest stage in young people with diabetes type 1. The purpose of th... | ['Adolescent', 'Brachial Artery', 'Carotid Artery, Common', 'Coronary Artery Disease', 'Diabetes Mellitus, Type 1', 'Diabetic Retinopathy', 'Endothelium, Vascular', 'Female', 'Humans', 'Male', 'Statistics, Nonparametric', 'Tunica Intima', 'Tunica Media', 'Ultrasonography'] | 16,813,713 | [['M01.060.057'], ['A07.015.114.139'], ['A07.015.114.186.200'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.4... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of abdominal vagotomy at proestrus on ovarian weight, ovarian antral follicles, and serum levels of gonadotropins, estradiol, and testosterone in the rat. | The effects of abdominal vagotomy at proestrus on ovarian weight and antral follicles greater than 150 microns diameter and on serum levels of gonadotropins and testosterone were assessed 24 and 48 h and 4 and 8 days after surgery. Serum levels of estradiol were assessed at 4 and 8 days. Vagotomy increased ovarian weig... | ['Animals', 'Estradiol', 'Estrus', 'Female', 'Follicle Stimulating Hormone', 'Gonadotropins, Pituitary', 'Luteinizing Hormone', 'Organ Size', 'Ovary', 'Rats', 'Rats, Inbred Strains', 'Testosterone', 'Vagotomy', 'Vagus Nerve'] | 3,084,987 | [['B01.050'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G08.686.195.500'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['D06.472.699.322.576', 'D06.472.699.631.525.343', 'D12.644.548.691.525.343'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.343.463', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Meningeal leukemia complicating chronic lymphocytic leukemia. | Two patients with classic chronic lymphocytic leukemia had meningeal leukemia as a complication of their disease. Intrathecal chemotherapy was successful in eradicating signs and symptoms of meningeal involvement. One of these patients is alive without evidence of central nervous system leukemia 30 months after diagnos... | ['Aged', 'Female', 'Follow-Up Studies', 'Humans', 'Injections, Spinal', 'Leukemia, Lymphoid', 'Male', 'Meningeal Neoplasms', 'Methotrexate', 'Middle Aged'] | 6,895,047 | [['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.580'], ['C04.557.337.428', 'C15.604.515.560', 'C20.683.515.528'], ['C04.588.614.250.580', 'C10.551.240.500'], ['D03.633.100.733.631.192.500'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Making light work: illuminating the future of biomedical optics. | In 1996, the Royal Society held a Discussion Meeting entitled 'Near-infrared spectroscopy and imaging of living systems'. In 2010, this topic was revisited in a Theo Murphy Royal Society Scientific Discussion Meeting entitled 'Making light work: illuminating the future of biomedical optics'. The second meeting provided... | ['Biomedical Engineering', 'Brain', 'Diagnostic Imaging', 'Equipment Design', 'Hemodynamics', 'Humans', 'Muscles', 'Optics and Photonics', 'Oximetry', 'Oxygen', 'Spectroscopy, Near-Infrared', 'Time Factors'] | 22,006,895 | [['H02.070', 'J01.293.140'], ['A08.186.211'], ['E01.370.350'], ['E05.320'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633', 'A10.690'], ['H01.671.617', 'J01.293.688'], ['E01.370.225.124.100.100.600', 'E01.370.370.380.600', 'E01.370.386.700.100.600', 'E05.200.124.100.100.600'], ['D01.268.18... | ['Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
A novel immunochromatographic assay using ultramarine blue particles as visible label for quantitative detection of hepatitis B virus surface antigen. | Ultramarine blue particles as a novel visible label has been used to develop immunochromatographic assay (ICA). The ultramarine blue particles, as a sodalite mineral with formula: (Na,Ca)8[(S,Cl,SO4,OH)2(Al6Si6O24)], can generate a blue visible signal were used as a label for ICA. Ultramarine blue particles were applie... | ['Hepatitis B Surface Antigens', 'Immunoassay', 'Particle Size', 'Pigments, Biological', 'Surface Properties'] | 31,948,577 | [['D23.050.327.495.500.475'], ['E05.478.566', 'E05.601.470'], ['G02.712'], ['D23.767'], ['G02.860']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A sterically stabilized immunolipoplex for systemic administration of a therapeutic gene. | A sterically stabilized immunolipoplex (TsPLP), containing an antitransferrin receptor single-chain antibody fragment (TfRscFv)-PEG molecule, has been developed to specifically and efficiently deliver a therapeutic gene to tumor cells. A postcoating preparation strategy was employed in which a DNA/lipid complex (lipopl... | ['Animals', 'Cell Line, Tumor', 'DNA', 'Female', 'Gene Targeting', 'Genetic Engineering', 'Genetic Therapy', 'Genetic Vectors', 'Humans', 'Injections, Intravenous', 'Male', 'Mice', 'Mice, Nude', 'Neoplasm Transplantation', 'Polyethylene Glycols', 'Prostatic Neoplasms', 'Receptors, Transferrin', 'Transfection', 'Transpl... | 15,229,629 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['D13.444.308'], ['E05.393.335'], ['E05.393.420'], ['E02.095.301', 'E05.393.420.301'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.64... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Using Social Media to Measure the Contribution of Red List Species to the Nature-Based Tourism Potential of African Protected Areas. | Cultural ecosystem services are defined by people's perception of the environment, which make them hard to quantify systematically. Methods to describe cultural benefits from ecosystems typically include resource-demanding survey techniques, which are not suitable to assess cultural ecosystem services for large areas. ... | ['Africa', 'Endangered Species', 'Refugium', 'Social Media', 'Travel', 'Wilderness'] | 26,068,111 | [['Z01.058'], ['B01.050.050.565', 'G16.500.275.157.049.250', 'N06.230.080.200', 'N06.230.124.049.250'], ['G16.500.275.683', 'G16.500.819'], ['L01.178.751', 'L01.224.230.110.500.750'], ['I03.883'], ['G16.500.275.965']] | ['Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Application of new coatings for vascular grafts based on polyacrylic systems with antiaggregating activity. | A study has been made of the behaviour of knitted and woven Dacron mesh used in the preparation of vascular grafts when coated with either a layer of poly(2-hydroxyethyl methacrylate) or co-polymers of 2-hydroxyethyl methacrylate with 5, 10 or 20 wt% of an acrylic derivative of salicylic acid, 2-methacryloyloxybenzoic ... | ['Animals', 'Biocompatible Materials', 'Blood Platelets', 'Blood Vessel Prosthesis', 'Cell Adhesion', 'Dogs', 'Materials Testing', 'Methacrylates', 'Platelet Aggregation', 'Platelet Aggregation Inhibitors', 'Polyethylene Terephthalates', 'Polyhydroxyethyl Methacrylate'] | 7,986,939 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['A11.118.188', 'A15.145.229.188'], ['E07.695.110'], ['G04.022'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.570'], ['D02.241.081.069.600'], ['G09.188.370.687', 'G09.188.390.600.640'], ['D27.505.954.502.780'], ['D05.750.728.764', 'D25.720.728.764'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effects of estrous synchronization on response to nitric oxide donors, nitric oxide synthase inhibitors, and endothelin-1 in vitro. | Two experiments were conducted to determine the effects of nitric oxide (NO) donors, endothelin-(ET-1), and NO synthase (NOS) inhibitors on bovine luteal function in vitro. In experiment 1, estrus in Brahman cows was synchronized with Synchro-Mate-B (SMB) and day-13-14 corpora luteal slices were weighed, diced and incu... | ['Animals', 'Cattle', 'Endothelin-1', 'Enzyme Inhibitors', 'Estrus', 'Female', 'In Vitro Techniques', 'Nitric Oxide Donors', 'Nitric Oxide Synthase', 'Radioimmunoassay'] | 15,560,115 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D12.644.276.400.225', 'D12.776.467.400.225', 'D23.529.400.225'], ['D27.505.519.389'], ['G08.686.195.500'], ['E05.481'], ['D27.505.519.656', 'D27.505.954.411.590'], ['D08.811.682.664.500.772'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bacteriuria increases the risk of edematous attacks in hereditary angioedema with C1-inhibitor deficiency. | Urinary tract infections are considered among the most common infectious disorders in humans. Various infections may have a role in inducing HAE attacks. Our study intended to evaluate bacteriuria in the urinalysis of patients with C1-INH-HAE. Urine specimens contributed by 139 patients with C1-INH-HAE at the annual co... | ['Adolescent', 'Adult', 'Bacteriuria', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Hereditary Angioedema Types I and II', 'Humans', 'Incidence', 'Male', 'Risk', 'Severity of Illness Index', 'Young Adult'] | 27,548,887 | [['M01.060.057'], ['M01.060.116'], ['C01.915.219', 'C12.777.892.219', 'C13.351.968.892.219'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C14.907.079.500.750', 'C17.800.862.945.066.500.750', 'C20.543.480.904.066.500.750'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Conservation genetics of neotropical pollinators revisited: microsatellite analysis suggests that diploid males are rare in orchid bees. | Allozyme analyses have suggested that Neotropical orchid bee (Euglossini) pollinators are vulnerable because of putative high frequencies of diploid males, a result of loss of sex allele diversity in small hymenopteran populations with single locus complementary sex determination. Our analysis of 1010 males from 27 spe... | ['Alleles', 'Animals', 'Bees', 'Diploidy', 'Evolution, Molecular', 'Female', 'Genetic Variation', 'Genetics, Population', 'Male', 'Microsatellite Repeats', 'Models, Genetic', 'Models, Statistical', 'Orchidaceae', 'Pollination', 'Sex Factors', 'Species Specificity'] | 20,662,922 | [['G05.360.340.024.340.030'], ['B01.050'], ['B01.050.500.131.617.720.500.500.875.387'], ['G05.700.264'], ['G05.045.250', 'G16.075.250'], ['G05.365'], ['H01.158.273.343.335'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500'], ['E05.599.395.397'], ['E05.318.740.500', 'E05.599.835', 'N... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11. | We analyzed two novel clusters of keratin-associated protein (KAP) genes on human chromosome 11 (11p15.5 and 11q13.5) in which we identified two known human KRTAP5 genes, KerA (=KRN1) and KerB, and nine novel KRTAP5 family genes. RT-PCR analysis of these KAP genes showed preferential expression in human hair root, sugg... | ['Amino Acid Sequence', 'Base Sequence', 'Chromosomes, Human, Pair 11', 'Cysteine', 'Gene Expression', 'Genome, Human', 'Glycine', 'Hair Follicle', 'Humans', 'Keratins', 'Molecular Sequence Data', 'Multigene Family', 'Open Reading Frames', 'Promoter Regions, Genetic', 'Sequence Alignment', 'Serine', 'Skin', 'Tissue Dis... | 15,144,888 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.187.520.300.325.355', 'G05.360.162.520.300.325.355'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['G05.297'], ['G05.360.340.350'], ['D12.125.481'], ['A10.272.497.500', 'A1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Structure-activity relationship of boronic acid derivatives of tyropeptin: proteasome inhibitors. | The structure-activity relationship of the boronic acid derivatives of tyropeptin, a proteasome inhibitor, was studied. Based on the structure of a previously reported boronate analog of tyropeptin (2), 41 derivatives, which have varying substructure at the N-terminal acyl moiety and P2 position, were synthesized. Amon... | ['Boron Compounds', 'Boronic Acids', 'Cell Line, Tumor', 'Dipeptides', 'Enzyme Inhibitors', 'Humans', 'Oligopeptides', 'Proteasome Endopeptidase Complex', 'Proteasome Inhibitors', 'Structure-Activity Relationship'] | 20,727,746 | [['D01.132', 'D02.203'], ['D01.029.260.110', 'D01.132.285', 'D02.203.200'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.644.456.345'], ['D27.505.519.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.456'], ['D05.500.562.500', 'D08.811.277.656.918', 'D08.811.600.730'], ['D27.505.519.389.745.705'], ['G0... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A newly identified polysaccharide from Ganoderma atrum attenuates hyperglycemia and hyperlipidemia. | A polysaccharide from Ganoderma atrum (PSG-1) was purified and characterized, and its hypoglycemic and hypolipidemic effects were investigated in high fat diet- and streptozotocin-induced type 2 diabetic rats. Oral administration of PSG-1 at 200 or 400 mg/kg body weight significantly reduced fasting blood glucose and s... | ['Animals', 'Diabetes Mellitus, Experimental', 'Fungal Polysaccharides', 'Ganoderma', 'Gene Expression Regulation', 'Hyperglycemia', 'Hyperlipidemias', 'Hypoglycemic Agents', 'Hypolipidemic Agents', 'Insulin Resistance', 'Lipids', 'Male', 'Rats', 'Rats, Wistar', 'bcl-2-Associated X Protein'] | 23,500,445 | [['B01.050'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D09.698.357', 'D23.050.202.283'], ['B01.300.179.120.760.338'], ['G05.308'], ['C18.452.394.952'], ['C18.452.584.500.500'], ['D27.505.696.422'], ['D27.505.519.186.071', 'D27.505.954.557.500'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['D10'... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Radiation pneumopathy. Our experience in the treatment of Hodgkin's disease with mantle-shaped field radiotherapy]. | The literature of the radiation pneumonitis is reviewed from the standpoint of the pathogenesis, histopathology and dependent parameters of the disease. A series of 125 patients treated with mantle fields for Hodgkin's disease between 1972/80 is studied. The radiation pneumonitis developed radiologically in 28 patients... | ['Animals', 'Hodgkin Disease', 'Humans', 'Pneumonia', 'Radiation Injuries', 'Radiography', 'Radiotherapy', 'Radiotherapy Dosage', 'Rats', 'Time Factors'] | 6,535,171 | [['B01.050'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.748.610', 'C08.381.677', 'C08.730.610'], ['C26.733', 'G01.750.748.500', 'N06.850.460.350.850.500', 'N06.850.810.300.360'], ['E01.370.350.700'], ['E02.815'], ['E02.815.639'], ['B01.050.... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
MR imaging depicts oxidative stress induced by methemoglobin. | PURPOSE: To correlate the effect of red blood cell hemoglobin on signal generation during magnetic resonance (MR) imaging and local oxidation of low-density lipoprotein (LDL).MATERIALS AND METHODS: Informed consent was obtained from all volunteers participating in this study, which was approved by the research ethics b... | ['Fatty Acids, Unsaturated', 'Humans', 'Lipid Peroxidation', 'Lipoproteins, LDL', 'Magnetic Resonance Imaging', 'Methemoglobin', 'Oxidation-Reduction', 'Oxidative Stress', 'Thiobarbituric Acid Reactive Substances'] | 20,829,533 | [['D10.251.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.515', 'G03.295.531.587'], ['D10.532.515', 'D12.776.521.550'], ['E01.370.350.825.500'], ['D12.776.124.400.599', 'D12.776.422.316.762.571'], ['G02.700', 'G03.295.531'], ['G03.673', 'G07.775.750'], ['D02.047.700.700', 'D27.720.470.410.750']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Social disclosure among coworkers without disabilities in supported employment settings. | The depth and breadth of reported self-disclosure by workers without disabilities (respondents) for three types of coworkers (i.e., work acquaintances, work friends, and social friends) were assessed. Reported self-disclosure of coworkers to supported employees was also compared, and the extent to which self-disclosure... | ['Adult', 'Employment, Supported', 'Female', 'Humans', 'Intellectual Disability', 'Interpersonal Relations', 'Male', 'Middle Aged', 'Peer Group', 'Rehabilitation, Vocational', 'Self Disclosure'] | 10,028,817 | [['M01.060.116'], ['N01.824.245.350', 'N02.421.784.644.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['F01.829.401'], ['M01.060.116.630'], ['F01.829.316.483'], ['E02.760.169.063.500.782', 'E02.831.782', 'N02.421.784.644'], ['F01.752.747... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A novel presentation of cryptococcal infection in a renal allograft recipient. | The population of immunosuppressed patients is growing rapidly because of the HIV epidemic and the rapid expansion in transplant medicine. These patients may present to a variety of clinical specialties with seemingly innocuous infections. We present here the first Irish case of primary cryptococcal cellulitis. The pat... | ['Antifungal Agents', 'Cryptococcosis', 'Cryptococcus', 'Dermatomycoses', 'Fluconazole', 'Humans', 'Immunocompromised Host', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Risk Factors', 'Skin'] | 10,967,854 | [['D27.505.954.122.136'], ['C01.150.703.248'], ['B01.300.381.258', 'B01.300.930.316'], ['C01.150.703.302', 'C01.800.200', 'C17.800.838.208'], ['D03.383.129.799.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.470'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['M01.060.116.630'], ['E05.318.740.6... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Implementation of the Canadian C-spine rule reduces cervical spine x-ray rate for alert patients with potential neck injury. | The objectives of this before-and-after study of alert, stable adult patients presenting to the Emergency Department of Western Hospital with potential neck injuries who were immobilized in hard cervical collars were to determine the impact of implementation of the Canadian C-spine rule on x-ray ordering rates and whet... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cervical Vertebrae', 'Chi-Square Distribution', 'Emergency Medicine', 'Emergency Service, Hospital', 'Female', 'Humans', 'Immobilization', 'Male', 'Middle Aged', 'Neck Injuries', 'Outcome and Process Assessment, Health Care', 'Radiography', 'Statistics, Nonparametri... | 15,707,805 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A02.835.232.834.151'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['H02.403.250'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Altered directionality in the Cre-LoxP site-specific recombination pathway. | The site-specific recombinase Cre must employ control mechanisms to impose directionality on recombination. When two recombination sites (locus of crossing over in phage P1, loxP) are placed as direct repeats on the same DNA molecule, collision between loxP-bound Cre dimers leads to excision of intervening DNA. If two ... | ['Attachment Sites, Microbiological', 'Bacteriophage P1', 'Base Sequence', 'Blotting, Western', 'Dimerization', 'Escherichia coli', 'Genes, Reporter', 'Genes, Viral', 'Integrases', 'Mutagenesis, Site-Directed', 'Recombination, Genetic', 'Repetitive Sequences, Nucleic Acid', 'Sequence Deletion', 'Viral Proteins'] | 11,492,999 | [['G05.360.340.024.079'], ['B04.123.150.500.300', 'B04.123.205.300', 'B04.280.090.500.300'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G02.206', 'G03.230'], ['B03.440.450.425.325.300', 'B03.660.250.15... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Is muscle glycogenolysis impaired in X-linked phosphorylase b kinase deficiency? | OBJECTIVE: It is unclear to what extent muscle phosphorylase b kinase (PHK) deficiency is associated with exercise-related symptoms and impaired muscle metabolism, because 1) only four patients have been characterized at the molecular level, 2) reported symptoms have been nonspecific, and 3) lactate responses to ischem... | ['Chromosomes, Human, X', 'Exercise Test', 'Glycogen', 'Glycogen Storage Disease Type V', 'Glycogen Storage Disease Type VIII', 'Glycogenolysis', 'Humans', 'Lactic Acid', 'Male', 'Middle Aged', 'Muscle Weakness', 'Muscle, Skeletal', 'Oxidative Stress', 'Phosphorylase Kinase', 'Physical Exertion', 'Point Mutation', 'Pro... | 18,401,027 | [['A11.284.187.520.300.325.680', 'A11.284.187.865.982.500', 'G05.360.162.520.300.325.680', 'G05.360.162.865.982.500'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['D05.750.078.562.388', 'D09.698.365.388'], ['C16.320.565.202.449.560', 'C18.452.648.202.449.560'], ['C16.320.322.217', 'C16.320.565.202.4... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fasting Enhances the Contrast of Bone Metastatic Lesions in 18 | 18F-fluciclovine (trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid) is an amino acid positron emission tomography (PET) tracer used for cancer staging (e.g., prostate and breast). Patients scheduled to undergo amino acid-PET are usually required to fast before PET tracer administration. However, there have been no ... | ['Animals', 'Bone Neoplasms', 'Bone and Bones', 'Breast Neoplasms', 'Carboxylic Acids', 'Cell Line, Tumor', 'Contrast Media', 'Cyclobutanes', 'Fasting', 'Female', 'Fluorodeoxyglucose F18', 'Male', 'Positron-Emission Tomography', 'Rats', 'Rats, Sprague-Dawley', 'Technetium Tc 99m Medronate'] | 28,468,238 | [['B01.050'], ['C04.588.149', 'C05.116.231'], ['A02.835.232', 'A10.165.265'], ['C04.588.180', 'C17.800.090.500'], ['D02.241'], ['A11.251.210.190', 'A11.251.860.180'], ['D27.505.259.500', 'D27.720.259'], ['D02.455.426.392.368.201'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['D09.254.229.500'], ... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A histomorphological study of tendon reconstruction to a hydroxyapatite-coated implant: regeneration of a neo-enthesis in vivo. | The attachment of tendons and ligaments to massive endoprostheses remains a clinical challenge due to the difficulty in achieving a soft tissue implant interface with a mechanical strength sufficient to transmit the forces necessary for locomotion. We have used an in vivo animal model to study patellar tendon attachmen... | ['Animals', 'Coated Materials, Biocompatible', 'Durapatite', 'Female', 'Knee Joint', 'Models, Animal', 'Osseointegration', 'Patella', 'Postoperative Complications', 'Prostheses and Implants', 'Sheep', 'Tendons'] | 15,475,215 | [['B01.050'], ['D25.130.420', 'J01.637.051.130.420'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['A02.835.583.475'], ['E05.598'], ['G11.427.213.140.570', 'G16.762.150.150.570'], ['A02.835.232.043.650.624', 'A02.835.232.730.500']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Early spontaneous ileal perforations in preterm infants: report of 4 cases]. | An ileal perforation occurred shortly after birth in 4 very premature newborns. Diagnosis was made on an abdominal distension with a pneumoperitoneum on X-ray. There were no biological, radiological nor histological signs of necrotizing enterocolitis. There were no digestive short- or long-term complications. According... | ['Diagnosis, Differential', 'Humans', 'Ileal Diseases', 'Infant, Newborn', 'Infant, Premature', 'Intestinal Perforation', 'Prognosis', 'Risk Factors'] | 16,084,073 | [['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.420'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['C06.405.469.557'], ['E01.789'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The rapid-onset dystonia parkinsonism mutation D923N of the Na+, K+-ATPase alpha3 isoform disrupts Na+ interaction at the third Na+ site. | Rapid-onset dystonia parkinsonism (RDP), a rare neurological disorder, is caused by mutation of the neuron-specific alpha3-isoform of Na(+), K(+)-ATPase. Here, we present the functional consequences of RDP mutation D923N. Relative to the wild type, the mutant exhibits a remarkable approximately 200-fold reduction of Na... | ['Animals', 'Binding Sites', 'COS Cells', 'Chlorocebus aethiops', 'Dystonic Disorders', 'Humans', 'Mutation, Missense', 'Parkinsonian Disorders', 'Potassium', 'Protein Binding', 'Sodium', 'Sodium-Potassium-Exchanging ATPase'] | 20,576,601 | [['B01.050'], ['G02.111.570.120'], ['A11.251.210.172.500', 'A11.329.228.220'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['C10.228.662.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590.650'], ['C10.228.140.079.862', 'C10.228.662.600'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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