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[Primary cardiac tumours in infancy]. | INTRODUCTION: Primary cardiac tumours are very rare in the paediatric age, their incidence varies from 0.0017 % to 0.28 %. More than 90 % are benign in nature. The most common variety is the rhabdomyoma, present in over 60 % of cases with tuberous sclerosis.MATERIAL AND METHODS: We performed a retrospective analysis of... | ['Adolescent', 'Child, Preschool', 'Echocardiography', 'Electrocardiography', 'Female', 'Heart Neoplasms', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Radiography, Thoracic', 'Retrospective Studies', 'Rhabdomyoma'] | 18,620,671 | [['M01.060.057'], ['M01.060.406.448'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['C04.588.894.309', 'C14.280.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E01.370.350.700.730'], ['E05.318.372.500.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The relationship between medical and psychological status in newly diagnosed gay men with AIDS. | We assessed current medical and psychological status in 50 homosexual/bisexual males who were within 3 months of the diagnosis of AIDS. Subjects had typically impaired cellular immunity, relatively well-maintained physical performance capacity, and reported surprisingly good current health status, in spite of significa... | ['Acquired Immunodeficiency Syndrome', 'Adaptation, Psychological', 'Adult', 'Homosexuality', 'Humans', 'Male', 'Middle Aged', 'Opportunistic Infections', 'Quality of Life', 'Sarcoma, Kaposi', 'Sick Role', 'Skin Neoplasms'] | 2,748,927 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['F01.058'], ['M01.060.116'], ['F01.145.802.975.500', 'G08.686.867.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C01.59... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Beta-D-xylosidase from Selenomonas ruminantium: thermodynamics of enzyme-catalyzed and noncatalyzed reactions. | Beta-D-Xylosidase/alpha-L-arabinofuranosidase from Selenomonas ruminantium is the most active enzyme known for catalyzing hydrolysis of 1,4-beta-D: -xylooligosaccharides to D-xylose. Temperature dependence for hydrolysis of 4-nitrophenyl-beta-D-xylopyranoside (4NPX), 4-nitrophenyl-alpha-L-arabinofuranoside (4NPA), and ... | ['Glycosides', 'Hydrogen-Ion Concentration', 'Molecular Structure', 'Selenomonas', 'Substrate Specificity', 'Temperature', 'Thermodynamics', 'Xylosidases'] | 18,953,511 | [['D09.408'], ['G02.300'], ['G02.111.570', 'G02.466'], ['B03.440.425.410.800.877'], ['G02.111.835'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['G01.906'], ['D08.811.277.450.950']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
In vitro inhibition of multiple cytochrome P450 isoforms by xanthone derivatives from mangosteen extract. | Mangosteen is a xanthone-containing fruit found in Southeast Asia for which health claims include maintaining healthy immune and gastrointestinal systems to slowing the progression of tumor growth and neurodegenerative diseases. Previous studies have identified multiple xanthones in the pericarp of the mangosteen fruit... | ['Chromatography, High Pressure Liquid', 'Cytochrome P-450 Enzyme Inhibitors', 'Enzyme Inhibitors', 'Garcinia mangostana', 'Humans', 'In Vitro Techniques', 'Isoenzymes', 'Kinetics', 'Mass Spectrometry', 'Microsomes, Liver', 'NADP', 'Pharmaceutical Preparations', 'Phenotype', 'Plant Extracts', 'Xanthones'] | 19,541,824 | [['E05.196.181.400.300'], ['D27.505.389.500', 'D27.505.519.389.335'], ['D27.505.519.389'], ['B01.650.940.800.575.912.250.859.625.333.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D08.811.348', 'D12.776.800.300'], ['G01.374.661', 'G02.111.490'], ['E05.196.566'], ['A11.284.835.540.541'], ['D03.63... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of exploration of spatial-relational object properties in the second and third years of life. | Within a perception-action framework, exploration is seen as a driving force in young children's development. Through exploration, children become skilled in perceiving the affordances in their environment and acting on them. Using a perception-action framework, the current study examined the development of children's ... | ['Age Factors', 'Child Development', 'Child, Preschool', 'Exploratory Behavior', 'Female', 'Humans', 'Infant', 'Male', 'Netherlands', 'Space Perception'] | 26,950,506 | [['N05.715.350.075', 'N06.850.490.250'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['F01.145.387', 'F01.658.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['Z01.542.651'], ['F02.463.593.778']] | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hypothermic coronary perfusion for myocardial protection during aortocoronary bypass. | Numerous methods have been used in an attempt to prevent myocardial injury that results from the interruption of aortic flow during cardiac operations. The authors describe a relatively simple means of inducing cardioplegia during coronary bypass surgery by coronary perfusion with cold lactated Ringer's solution throug... | ['Coronary Artery Bypass', 'Female', 'Humans', 'Hypothermia, Induced', 'Male', 'Middle Aged', 'Perfusion'] | 307,979 | [['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.258.750'], ['M01.060.116.630'], ['E05.680']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Early clinical experience enhances third-year pediatrics clerkship performance. | PURPOSE: To determine whether clinical experiences in the preclinical years improve medical students' performances in a third-year clerkship.METHOD: A cohort study reviewed the pediatrics clerkship performances of 400 Eastern Virginia Medical School students in the graduating classes of 1996 through 1999. The first two... | ['Analysis of Variance', 'Clinical Clerkship', 'Clinical Competence', 'Cohort Studies', 'Curriculum', 'Education, Medical, Undergraduate', 'Educational Measurement', 'Humans', 'Pediatrics', 'Virginia'] | 10,587,688 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['I02.358.105'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['I02.158'], ['I02.358.399.450'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Demonstration of functional border zone with myocardial contrast echocardiography in human hearts. Simultaneous analysis of myocardial perfusion and wall motion abnormalities. | BACKGROUND: Although the presence of a functional border zone (FBZ), defined as the nonischemic but asynergic myocardium adjacent to the ischemic area, has been demonstrated in animal hearts, it is not known whether this zone exists in humans.METHODS AND RESULTS: Myocardial contrast echocardiography (MCE) was performed... | ['Adult', 'Aged', 'Angioplasty, Balloon, Coronary', 'Contrast Media', 'Coronary Circulation', 'Coronary Disease', 'Echocardiography', 'Female', 'Heart', 'Humans', 'Male', 'Middle Aged'] | 8,339,408 | [['M01.060.116'], ['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['D27.505.259.500', 'D27.720.259'], ['G09.330.100.324'], ['C14.280.647.250', 'C... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identification of TLR inducing Th1-responsive Leishmania donovani amastigote-specific antigens. | Leishmania is known to elicit Th2 response that causes leishmaniasis progression; on the other hand, Th1 cytokines restricts amastigote growth and disease progression. In this study, we report the potential of two leishmanial antigens (65 and 98 kDa, in combination) which enhance strong macrophage effector functions, v... | ['Animals', 'Antigens, Protozoan', 'Cell Line', 'Cell Proliferation', 'Cytokines', 'Immunity, Innate', 'Leishmania donovani', 'Macrophages', 'Mice', 'Th1 Cells', 'Toll-Like Receptors'] | 21,858,498 | [['B01.050'], ['D23.050.293'], ['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G12.450.564'], ['B01.268.475.868.488.230'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.050.150.900.649.313.992.635.505.500'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of Radio Frequency Identification to Establish Emergency Medical Service Offload Times. | Emergency medical services (EMS) crews often wait for emergency department (ED) beds to become available to offload their patients. Presently there is no national benchmark for EMS turnaround or offload times, or method for objectively and reliably measuring this. This study introduces a novel method for monitoring off... | ['Ambulances', 'Baltimore', 'Emergency Medical Services', 'Emergency Service, Hospital', 'Hospitals, Urban', 'Humans', 'Maryland', 'Radio Frequency Identification Device', 'Time Factors', 'Transportation of Patients'] | 26,382,887 | [['J01.937.500.050', 'N02.421.297.879.100'], ['Z01.107.567.875.500.500.100', 'Z01.433.100'], ['N02.421.297'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['N02.278.421.660'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.075.418', 'Z01.107.567.875.500.500'], ['E07.715... | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Characterization of a novel SCN5A mutation associated with Brugada syndrome reveals involvement of DIIIS4-S5 linker in slow inactivation. | OBJECTIVE: Mutations in SCN5A, the gene encoding the alpha-subunit of the cardiac sodium channel (Na(v)1.5), have been associated with various inherited arrhythmia syndromes, including Brugada syndrome (BrS). Here, we report the functional consequences of a novel missense SCN5A mutation, G1319V, identified in a BrS pat... | ['Adult', 'Amino Acid Sequence', 'Brugada Syndrome', 'Cell Line', 'Electrocardiography', 'Electrophysiological Phenomena', 'Humans', 'Kidney', 'Male', 'Molecular Sequence Data', 'Muscle Proteins', 'Mutation, Missense', 'NAV1.5 Voltage-Gated Sodium Channel', 'Patch-Clamp Techniques', 'Phenotype', 'Protein Structure, Ter... | 17,854,786 | [['M01.060.116'], ['G02.111.570.060', 'L01.453.245.667.060'], ['C14.280.067.322', 'C14.280.123.250', 'C16.320.100'], ['A11.251.210'], ['E01.370.370.380.240', 'E01.370.405.240'], ['G07.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['L01.453.245.667'], ['D12.776.210.500'], ['G05.365.590.650'], ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Therapeutic ultrasound: the effects upon cutaneous blood flow in humans. | The premise of the current crossover, randomised, double-blinded and controlled study was to ascertain the physiologic effects of pulsed and continuous ultrasound (US) upon cutaneous blood flow in humans as measured by laser Doppler flowmetry. Ten healthy volunteers (5 male, 5 female; aged 18 to 36 y) were assigned to ... | ['Adolescent', 'Adult', 'Blood Flow Velocity', 'Cross-Over Studies', 'Double-Blind Method', 'Female', 'Forearm', 'Humans', 'Laser-Doppler Flowmetry', 'Male', 'Regional Blood Flow', 'Skin', 'Skin Temperature', 'Ultrasonic Therapy'] | 17,306,698 | [['M01.060.057'], ['M01.060.116'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['A01.378.800.585'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.370.475'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sequence analysis and structure prediction of aminoglycoside-resistance 16S rRNA:m7G methyltransferases. | Methylation of G1405 within bacterial 16S ribosomal RNA results in high-level resistance to specific combinations of aminoglycoside antibiotics. Only a few closely related methyltransferases (MTases), which carry out the respective modification (here dubbed "Agr", for aminoglycoside resistance), are known. It is not cl... | ['Actinomycetales', 'Amino Acid Sequence', 'Aminoglycosides', 'Anti-Bacterial Agents', 'Drug Resistance, Microbial', 'Forecasting', 'Methyltransferases', 'Micromonospora', 'Models, Molecular', 'Molecular Sequence Data', 'Sequence Analysis, Protein', 'Sequence Homology, Amino Acid'] | 11,518,396 | [['B03.510.024.049'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D09.408.051'], ['D27.505.954.122.085'], ['G06.225', 'G07.690.773.984.269'], ['I01.320'], ['D08.811.913.555.500'], ['B03.300.390.400.500.500', 'B03.510.024.925.500', 'B03.510.415.400.500.500', 'B03.510.460.410.500.500'], ['E05.599.595'], ['L01.453.245.6... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
Nosocomial infection with gentamicin-carbenicillin-resistant Pseudomonas aeruginosa. | Pseudomonas aeruginosa resistant to both gentamicin and carbenicillin was isolated with increasing frequency at the Cincinnati Veterans Administration Hospital during the period 1971 to 1974. A comparison of patients from whom P. aeruginosa was isolated during this period failed to reveal any significant clinical diffe... | ['Anti-Bacterial Agents', 'Carbenicillin', 'Gentamicins', 'Humans', 'Penicillin Resistance', 'Pseudomonas Infections', 'Pseudomonas aeruginosa', 'Time Factors'] | 825,033 | [['D27.505.954.122.085'], ['D02.065.589.099.750.750.170', 'D02.886.108.750.750.170', 'D03.633.100.300.750.750.170'], ['D09.408.051.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.099.225.500.600', 'G06.225.347.500.600', 'G07.690.773.984.269.347.500.600'], ['C01.150.252.400.739'], ['B03.440.400.425.625.625... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Surveillance of surgical wound infections following open heart surgery. | OBJECTIVE: To define accurate wound infection rates for the cardiac surgery service based on site of infection and characterization as "deep" or "incisional" and to determine whether a correctable cause for an apparent increase in deep wound infection rates existed.DESIGN: Observational.SETTING: Tertiary-care teaching ... | ['Cardiac Surgical Procedures', 'Cardiology Service, Hospital', 'Coronary Artery Bypass', 'Hair Removal', 'Hospital Bed Capacity, 500 and over', 'Hospitals, Teaching', 'Humans', 'New York', 'Population Surveillance', 'Preoperative Care', 'Risk Factors', 'Surgical Wound Infection'] | 1,787,309 | [['E04.100.376', 'E04.928.220'], ['N02.278.216.500.968.215', 'N04.452.442.452.422.215'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E02.218.372'], ['N02.278.306.472.300'], ['N02.278.020.300', 'N02.278.421.639'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.075.437', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
An extraction method of positive blood cultures for direct identification of Candida species by Vitek MS matrix-assisted laser desorption ionization time of flight mass spectrometry. | Candida spp. are an important cause of nosocomial bloodstream infections. Currently, complete identification of yeasts with conventional methods takes several days. We report here the first evaluation of an extraction method associated with the Vitek MS matrix-assisted laser desorption ionization time of flight mass sp... | ['Blood', 'Candida', 'Candidemia', 'Humans', 'Microbiological Techniques', 'Mycology', 'Sensitivity and Specificity', 'Specimen Handling', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Time Factors'] | 23,373,445 | [['A12.207.152', 'A15.145'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['C01.150.703.160.175.500', 'C01.150.703.492.500.500', 'C01.757.360.150', 'C23.550.470.790.500.360.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875', 'E05.200.875'], ['H01.158.273.540.553'], ['E05.318.37... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
How treatment improvement in ADHD and cocaine dependence are related to one another: A secondary analysis. | BACKGROUND: Attention-deficit hyperactivity disorder (ADHD) is overrepresented among individuals seeking treatment for substance use disorders. We previously reported that treatment with extended release mixed amphetamine salts (MAS-XR) increased abstinence, compared to placebo, among patients with co-occurring ADHD an... | ['Adolescent', 'Adult', 'Amphetamines', 'Attention Deficit Disorder with Hyperactivity', 'Central Nervous System Stimulants', 'Cocaine-Related Disorders', 'Delayed-Action Preparations', 'Double-Blind Method', 'Female', 'Humans', 'Male', 'Middle Aged', 'Time Factors', 'Treatment Outcome', 'Young Adult'] | 29,775,957 | [['M01.060.057'], ['M01.060.116'], ['D02.092.471.683.152'], ['F03.625.094.150'], ['D27.505.696.282', 'D27.505.954.427.220'], ['C25.775.300', 'F03.900.300'], ['D26.255.210', 'E02.319.300.253'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efferent controlled integrating fuctions of primary vestibular afferents. | The vestibular type II receptor cells of mammalians are multiply innervated. Their afferents are integrating neurons consisting of many inputs but only one output. They transform the irregular spontaneous input activity into a regular output. Under the influence of efferent activity following the stimulation of the con... | ['Animals', 'Cats', 'Cold Temperature', 'Ear, Inner', 'Neurons, Afferent', 'Neurons, Efferent', 'Therapeutic Irrigation', 'Vestibular Nerve', 'Vestibule, Labyrinth', 'Water'] | 313,654 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ocular Complications in Influenza Virus Infection. | Purpose: To describe a case series of ocular complications associated with upper respiratory tract infections. Methods: Four patients aged 21-61 years (three females, one male) had confirmed ocular complications connected with a general upper respiratory tract infection with myalgia and fever. Ophthalmological examinat... | ['Adult', 'DNA, Viral', 'Female', 'Fluorescein Angiography', 'Fundus Oculi', 'Humans', 'Incidence', 'Influenza A virus', 'Influenza, Human', 'Male', 'Middle Aged', 'Poland', 'Retina', 'Retinal Diseases', 'Risk Factors', 'Slit Lamp Microscopy', 'Tomography, Optical Coherence', 'Visual Acuity', 'Young Adult'] | 29,420,099 | [['M01.060.116'], ['D13.444.308.568'], ['E01.370.370.050.350', 'E01.370.380.250'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['B04.820.480.968.405.400'], ['C01.748.310', 'C01.925... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
High variability of nitrosamine metabolism among individuals: role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans. | We undertook this study to answer several questions regarding nitrosamine metabolism. Kinetics of nitrosamine metabolism showed the involvement of at least two enzymes in the dealkylation of N-nitrosodiethylamine (NDEA) and N-nitrosodimethylamine (NDMA) in mouse liver microsomes. Coumarin inhibited both reactions compe... | ['Animals', 'Aryl Hydrocarbon Hydroxylases', 'Biotransformation', 'Cytochrome P-450 CYP2A6', 'Cytochrome P-450 CYP2E1', 'Cytochrome P-450 Enzyme System', 'Diethylnitrosamine', 'Dimethylnitrosamine', 'Humans', 'Kinetics', 'Male', 'Mice', 'Mice, Inbred DBA', 'Microsomes, Liver', 'Mixed Function Oxygenases', 'Oxidoreducta... | 8,352,885 | [['B01.050'], ['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['D08.244.453.491.250', 'D08.811.682.690.708.170.450.250', 'D12.776.422.220.453.491.250'], ['D08.244.453.491.375', 'D08.811.682.662.582.338', 'D08.811.682.690.708.170.450.375', 'D1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relationship between lung injury and lung lipid peroxidation caused by recurrent endotoxemia. | We compared the relationship between lung lipid peroxidation and the histologic and physiologic changes seen after repeated doses of low dose endotoxin in unanesthetized sheep. Thirty-two sheep with lung lymph fistula were given from 1 to 10 doses of 1 micrograms/kg Escherichia coli endotoxin, 12 h apart. Animals were ... | ['Animals', 'Biopsy', 'Dose-Response Relationship, Drug', 'Endotoxins', 'Escherichia coli', 'Lipid Peroxidation', 'Lipid Peroxides', 'Lung', 'Malondialdehyde', 'Pneumonia', 'Recurrence', 'Sheep', 'Sheep Diseases', 'Time Factors'] | 2,653,147 | [['B01.050'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['G07.690.773.875', 'G07.690.936.500'], ['D23.946.123.329'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.111.515', 'G03.295.531.587'], ['D01.248.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alternating current electric field effects on neural stem cell viability and differentiation. | Methods utilizing stem cells hold tremendous promise for tissue engineering applications; however, many issues must be worked out before these therapies can be routinely applied. Utilization of external cues for preimplantation expansion and differentiation offers a potentially viable approach to the use of stem cells ... | ['Alginates', 'Animals', 'Astrocytes', 'Cell Culture Techniques', 'Cell Differentiation', 'Cell Survival', 'Electromagnetic Fields', 'Glucuronic Acid', 'Hexuronic Acids', 'Hydrogel, Polyethylene Glycol Dimethacrylate', 'Mice', 'Microelectrodes', 'Microscopy, Confocal', 'Microspheres', 'Neurons', 'Particle Size', 'Stem ... | 20,205,161 | [['D09.698.068'], ['B01.050'], ['A08.637.200', 'A11.650.200'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.152'], ['G04.346'], ['G01.358.500.260', 'G01.358.750.500'], ['D02.241.081.844.915.162.249', 'D02.241.152.811.162.500', 'D02.241.511.902.915.162.500', 'D09.811.922.162.500'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
CES1A -816C as a genetic marker to predict greater platelet clopidogrel response in patients with percutaneous coronary intervention. | This study was designed to determine whether CES1A -816A/C polymorphism could be associated with altered clopidogrel response. Recruited patients were pretreated with 300 mg clopidogrel loading dose before undergoing percutaneous coronary intervention for stenting and genotyped with CYP2C19 *2, *3, or *17, and CES1A -8... | ['Adenosine Diphosphate', 'Aged', 'Aryl Hydrocarbon Hydroxylases', 'Clopidogrel', 'Cohort Studies', 'Cytochrome P-450 CYP2C19', 'Female', 'Genetic Markers', 'Genetic Variation', 'Genotype', 'Humans', 'Linear Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Percutaneous Coronary Intervention', 'Platelet Aggrega... | 24,508,947 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['M01.060.116.100'], ['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['D02.886.778.823.500.500', 'D03.383.725.849.500.500', 'D03.383.903.830.500.500', 'D03.633.100.928.500.500'], ['E05.318.372.500.750', 'N05.7... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Medical toxicology. | Chest pain is a manifestation of cocaine toxicity, but whether it is of an ischemic origin is unclear. A reexamination of the role of acetylcysteine in treating acetaminophen overdose has led to substantial changes in the indications for its use. | ['Drug-Related Side Effects and Adverse Reactions', 'Humans', 'Toxicology', 'United States'] | 8,182,849 | [['C25.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.158.891', 'H02.884'], ['Z01.107.567.875']] | ['Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Prevalence of abnormal uterine bleeding according to new International Federation of Gynecology and Obstetrics classification in Chinese women of reproductive age: A cross-sectional study. | The PALM-COEIN classification for causes of abnormal uterine bleeding (AUB) was proposed by the International Federation of Gynecology and Obstetrics (FIGO) in 2011, which has been gradually applied in the diagnosis of AUB in the past 2 years in China. However, there are no reports yet on the causes of chronic AUB amon... | ['Adolescent', 'Adult', 'Age Distribution', 'China', 'Chronic Disease', 'Cross-Sectional Studies', 'Female', 'Humans', 'Middle Aged', 'Prevalence', 'Uterine Hemorrhage', 'Young Adult'] | 30,075,511 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['Z01.252.474.164'], ['C23.550.291.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.93... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Appropriate treatment of benign prostatic hyperplasia; refining the indications for treatment by systematic analysis of expert opinion]. | OBJECTIVE: To assess systematically the opinion of urology experts regarding the appropriateness of indications for treatment of benign prostatic hyperplasia (BPH) and to evaluate the potential use of these expert opinions for the refinement of treatment guidelines.DESIGN: Modified Delphi procedure.METHODS: A panel of ... | ['Adrenergic alpha-Antagonists', 'Delphi Technique', 'Enzyme Inhibitors', 'Finasteride', 'Humans', 'Logistic Models', 'Male', 'Prostatic Hyperplasia', 'Transurethral Resection of Prostate', 'Urology', 'Workforce'] | 10,608,977 | [['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['L01.906.197'], ['D27.505.519.389'], ['D04.210.500.054.079.500', 'D04.210.500.925.100.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.53... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Phospholipid scramblase 1 binds to the promoter region of the inositol 1,4,5-triphosphate receptor type 1 gene to enhance its expression. | Phospholipid scramblase 1 (PLSCR1) is a multiply palmitoylated, endofacial membrane protein originally identified based on its capacity to promote accelerated transbilayer phospholipid movement in response to Ca(2+). Recent evidence suggests that this protein also participates in cell response to various growth factors... | ['Animals', 'Antiviral Agents', 'Base Sequence', 'Binding Sites', 'Blotting, Northern', 'Blotting, Western', 'Calcium', 'Calcium Channels', 'Cell Membrane', 'Cell Nucleus', 'Cell Proliferation', 'Cells, Cultured', 'Cloning, Molecular', 'CpG Islands', 'DNA, Complementary', 'Fibroblasts', 'Gene Deletion', 'Gene Expressio... | 16,091,359 | [['B01.050'], ['D27.505.954.122.388'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D01.268.552.100', 'D01.552.539.288', 'D23.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Blogs as a way to elicit feedback on research and engage stakeholders. | AIM: To reflect on the potential of blogs to enhance engagement with research, create a dialogue between researchers and nurses, and provide feedback to researchers.BACKGROUND: Blogs can create opportunities to share ideas, provide an arena for interaction, and rapidly and effectively initiate dialogue and feedback on ... | ['Feedback', 'Internet', 'Nursing Research'] | 25,587,866 | [['L01.906.394.211'], ['L01.224.230.110.500'], ['H01.770.644.145.390', 'H02.478.395', 'N04.590.233.508.613']] | ['Information Science [L]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Effects of colestipol, clofibrate, and placebo on plasma lipoproteins of patients with hypercholesterolemia. | To evaluate the effectiveness of colestipol and clofibrate in patients with hypercholesterolemia and normal concentrations of triglycerides, 27 patients were randomized into three groups, and colestipol, clofibrate, and avicel powder placebo were compared for effects on concentration of total plasma lipid and lipoprote... | ['Adult', 'Aged', 'Cholesterol', 'Clofibrate', 'Colestipol', 'Female', 'Humans', 'Hyperlipoproteinemia Type II', 'Lipids', 'Lipoproteins', 'Lipoproteins, LDL', 'Male', 'Middle Aged', 'Placebos', 'Polyamines', 'Random Allocation'] | 7,464,561 | [['M01.060.116'], ['M01.060.116.100'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D02.241.081.114.968.500.500.195', 'D02.355.726.305.500.195', 'D02.455.426.559.389.657.654.305.500.195'], ['D02.092.782.200', 'D05.750.200', 'D25.720.200', 'J01.637.051.720.200'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Cell-free synthesis, proteolytic processing, core glycosylation, and amino terminal sequence of rabbit pre-alpha-lactalbumin. | Two different forms of alpha-lactalbumin were isolated from rabbit milk and partially characterized. The major and the minor species had apparent molecular weights of 18000 and 14000, respectively, according to their electrophoretic mobilities on SDS polyacrylamide gels. Analyses of their amino acid compositions and am... | ['Amino Acid Sequence', 'Animals', 'Carbohydrate Metabolism', 'Cell-Free System', 'Female', 'Intracellular Membranes', 'Lactalbumin', 'Mammary Glands, Animal', 'Microsomes', 'Milk', 'Molecular Weight', 'Pregnancy', 'Protein Biosynthesis', 'Protein Precursors', 'Rabbits'] | 6,821,155 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.158', 'G03.191'], ['A11.284.835.168'], ['A11.284.149.450', 'A11.284.835.514'], ['D12.776.034.398', 'D12.776.256.159.750.816.250'], ['A10.336.482', 'A13.589'], ['A11.284.835.540'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Nosocomial spread of Haemophilus influenzae type b infection documented by outer membrane protein subtype analysis. | This report provides evidence of nosocomial transmission of Haemophilus influenzae type b infection between two children in an acute care hospital. In the past, transmission of infection between these children would have gone unrecognized, because the isolates from the respective cases differed in susceptibility to amp... | ['Ampicillin', 'Bacterial Proteins', 'Child, Preschool', 'Cross Infection', 'Female', 'Haemophilus Infections', 'Haemophilus influenzae', 'Humans', 'Infant', 'Male', 'Membrane Proteins', 'Penicillin Resistance'] | 6,602,214 | [['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['D12.776.097'], ['M01.060.406.448'], ['C01.248', 'C23.550.291.875.500'], ['C01.150.252.400.700.433'], ['B03.440.450.600.450.330', 'B03.660.250.550.290.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A manifold support for molecular genetic reactions. | Large numbers of samples can be efficiently processed through sequential reaction steps using a 96-pronged support that projects into individual microtiter wells. The support was constructed by creating a porous surface on a disposable polystyrene manifold, with avidin coupled to this greatly expanded surface. The shap... | ['Avidin', 'Bacterial Proteins', 'Biotin', 'DNA', 'Kinetics', 'Molecular Biology', 'Polymerase Chain Reaction', 'Polystyrenes', 'Sepharose', 'Streptavidin'] | 8,323,026 | [['D12.776.034.614.300', 'D12.776.256.159.157.663.300', 'D12.776.290.663.100', 'D12.776.395.175'], ['D12.776.097'], ['D03.383.129.308.080', 'D08.211.096'], ['D13.444.308'], ['G01.374.661', 'G02.111.490'], ['H01.158.201.636', 'H01.158.273.343.595', 'H01.181.122.650'], ['E05.393.620.500'], ['D02.455.426.559.389.150.750.8... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Morphological properties of surface-treated carbon nanotubes in cement-based composites. | The morphological properties of the multi-walled carbon nanotubes (MWCNTs) reinforced Portland cement composites were investigated. MWCNTs with addition of up to 0.15 wt% of cement were incorporated to Portland cement with a water to cement ratio of 0.35. The porosity and pore size distribution of the composites were m... | ['Adhesives', 'Crystallization', 'Macromolecular Substances', 'Materials Testing', 'Molecular Conformation', 'Nanotubes, Carbon', 'Particle Size', 'Porosity', 'Surface Properties'] | 23,421,224 | [['D27.720.013', 'J01.637.016'], ['E05.196.300', 'G02.171'], ['D05'], ['E05.570'], ['G02.111.570.820'], ['D01.268.150.250.500', 'J01.637.512.850.500'], ['G02.712'], ['G01.374.710'], ['G02.860']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Curcumin-mediated photodynamic inactivation of Candida albicans in a murine model of oral candidiasis. | In vitro investigations of curcumin-mediated photodynamic therapy (PDT) are encouraging, but there is a lack of reliable in vivo evidence of its efficacy. This study describes the photoinactivation of Candida albicans in a murine model of oral candidiasis, using curcumin as a photosensitizer. Forty immunosuppressed mic... | ['Administration, Topical', 'Animals', 'Candida albicans', 'Candidiasis, Oral', 'Colony Count, Microbial', 'Curcumin', 'Disease Models, Animal', 'Female', 'Light', 'Mice', 'Photochemotherapy', 'Photosensitizing Agents', 'Treatment Outcome'] | 22,934,533 | [['E02.319.267.120'], ['B01.050'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['C01.150.703.160.180', 'C07.465.130'], ['E01.370.225.875.220', 'E05.200.875.220'], ['D02.455.326.146.485.222.222', 'D02.455.426.559.389.657.166.200', 'D02.455.426.559.694.222'], ['C22.232', 'E05.598.500', 'E05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Frontal N30 potential following a sustained voluntary movement. | With 6 male subjects we investigated whether the decreased amplitude in the frontal N30 potential of Somatosensory Evoked Potentials is related to a sustained voluntary movement or not. We concluded that the diminution of frontal N30 was also closely related to the sustained voluntary movement. | ['Evoked Potentials, Somatosensory', 'Frontal Lobe', 'Humans', 'Male', 'Movement'] | 8,570,337 | [['G07.265.216.500.400', 'G11.561.200.500.400'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activation of the dentate nucleus in a verb generation task: A 7T MRI study. | There is increasing evidence of a topographic organization within the human cerebellar cortex for motor and non-motor functions. Likewise, a subdivision of the dentate nucleus in a more dorsal and rostral motor domain and a more ventral and caudal non-motor domain has been proposed by Dum and Strick (2003) based on ana... | ['Adult', 'Brain', 'Brain Mapping', 'Cerebellar Nuclei', 'Humans', 'Image Interpretation, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Speech', 'Young Adult'] | 21,640,191 | [['M01.060.116'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.132.810.428.200.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['F01.145.2... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
[Overexpression of p27(KIP1) induced by Bak gene leads to the arrest in G(1) phase of HCC-9204 cell line]. | OBJECTIVE: To explore whether p27(KIP1) plays an important role in prolonging cell cycle in G(1) phase and leading to apoptosis of HCC-9204 cells.METHODS: A model of Bak-induced cell cycle arrest in G(1) phase and subsequent apoptosis was established. p27(KIP1) was obtained from the model and sequenced afterwards. A zi... | ['Apoptosis', 'Carcinoma, Hepatocellular', 'Cell Cycle Proteins', 'Cyclin-Dependent Kinase Inhibitor p27', 'G1 Phase', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Liver Neoplasms', 'Membrane Proteins', 'Tumor Cells, Cultured', 'Tumor Suppressor Proteins', 'bcl-2 Homologous Antagonist-Killer Protein'] | 11,509,132 | [['G04.146.954.035'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['D12.776.167'], ['D12.644.360.225.600', 'D12.776.167.187.600', 'D12.776.476.225.600', 'D12.776.624.776.355.600'], ['G04.144.500.320'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Risk factors in community-acquired chronic hepatitis C virus infection: a case-control study in Italy. | AIMS/METHODS: A case-control study was carried out in Italy to assess the risk factors associated with chronic hepatitis C virus infection. Five hundred consecutive chronic anti-hepatitis C virus positive cases and 500 sex and exactly age-matched anti-hepatitis C virus negative/HBsAg negative controls entered the study... | ['Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Case-Control Studies', 'Chronic Disease', 'Community-Acquired Infections', 'Female', 'Hepatitis C', 'Humans', 'Italy', 'Male', 'Middle Aged', 'Odds Ratio', 'Risk Factors', 'Sex Distribution'] | 8,907,564 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.291.500'], ['C01.234'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
High aspect ratio materials: role of surface chemistry vs. length in the historical "long and short amosite asbestos fibers". | In nanotoxicology the question arises whether high aspect ratio materials should be regarded as potentially pathogenic like asbestos, merely on the base of their biopersistence and length to diameter ratio. A higher pathogenicity of long asbestos fibers is associated to their slower clearance and frustrated phagocytosi... | ['Alveolar Epithelial Cells', 'Asbestos, Amosite', 'Ascorbic Acid', 'Cell Line, Tumor', 'Crystallography, X-Ray', 'Enzyme Activation', 'Free Radicals', 'Humans', 'Iron', 'Nanotechnology', 'Nitric Oxide Synthase', 'Oxidants', 'Particle Size', 'Spectrum Analysis, Raman', 'Surface Properties'] | 20,718,637 | [['A04.411.715.100', 'A11.436.081'], ['D01.524.500.040', 'D01.578.725.050.050.050', 'D01.578.725.500.040', 'D01.837.725.700.760.070.050.060', 'D01.837.725.700.760.535.040'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.196.309.742.225'], ['G02.111.263', 'G... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Comparison of olanexidine versus povidone-iodine for preventing surgical site infection in gastrointestinal surgery: study protocol for a multicentre, single-blind, randomised controlled clinical trial. | INTRODUCTION: The prevalence of surgical site infection (SSI) remains higher in gastrointestinal surgery than in other surgeries. Although several guidelines have indicated the efficacy of chlorhexidine and povidone-iodine in reducing the SSI rate, the optimal recommendation has still not been established. Therefore, i... | ['Anti-Infective Agents, Local', 'Biguanides', 'Digestive System Surgical Procedures', 'Humans', 'Povidone-Iodine', 'Research Design', 'Surgical Wound Infection'] | 31,142,533 | [['D27.505.954.122.187'], ['D02.078.370.141'], ['E04.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.475.557.500', 'D02.455.326.271.884.533.710', 'D03.383.773.812.615.630', 'D05.750.716.721.838.745', 'D25.720.716.721.838.745', 'J01.637.051.720.716.721.838.745'], ['E05.581.500', 'H01.770.644.728'], ['C01.9... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Follow up and evaluation of the Victorian first-trimester combined screening programme for Down syndrome and trisomy 18. | OBJECTIVE: The objective of this study was to follow up and evaluate the statewide first-trimester combined screening programme for Down syndrome and trisomy 18 at Genetic Health Services Victoria, Australia.DESIGN: Retrospective population cohort.SETTING: Maternal Serum Screening Laboratory records.SAMPLE: All women s... | ['Adult', 'Chromosomes, Human, Pair 18', 'Cohort Studies', 'Down Syndrome', 'Female', 'Follow-Up Studies', 'Genetic Testing', 'Humans', 'Maternal Age', 'Pregnancy', 'Pregnancy Trimester, First', 'Prenatal Diagnosis', 'Retrospective Studies', 'Risk Factors', 'Sensitivity and Specificity', 'Trisomy', 'Victoria'] | 17,501,960 | [['M01.060.116'], ['A11.284.187.520.300.415.430', 'G05.360.162.520.300.415.430'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.5... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Factors impacting self-perceived readiness for residency training: results of a national survey of postgraduate year 1 residents. | OBJECTIVE: To examine the factors impacting postgraduate year 1 (PGY1) residents' self-perceived readiness for residency.METHODS: A total of 1801 residents who matched in American Society of Health-System Pharmacists (ASHP)-accredited PGY1 programs were e-mailed individualized invitations to take an online survey. The ... | ['Adult', 'Clinical Competence', 'Communication', 'Education, Pharmacy, Graduate', 'Female', 'Humans', 'Knowledge', 'Male', 'Pharmacy Residencies', 'Prospective Studies', 'Self Efficacy', 'Surveys and Questionnaires', 'Time Factors'] | 24,674,909 | [['M01.060.116'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['F01.145.209', 'L01.143'], ['I02.358.337.550', 'I02.358.525.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.468'], ['I02.358.525.741', 'I02.358.750.500'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.7... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Exploring association between gastrointestinal heat retention syndrome and recurrent respiratory tract infections in children: a prospective cohort study. | BACKGROUND: Recurrent respiratory tract infections (RRTIs) have a negative impact on both children's health and family wellbeing. Deficiency of ZhengQi used to be an instinct factor driving RRTI in Traditional Chinese Medicine (TCM). Our clinical observations suggest that children with gastrointestinal heat retention s... | ['Beijing', 'Body Mass Index', 'Child', 'Child, Preschool', 'Feces', 'Female', 'Gastrointestinal Tract', 'Hot Temperature', 'Humans', 'Incidence', 'Logistic Models', 'Male', 'Medicine, Chinese Traditional', 'Prospective Studies', 'Qi', 'Recurrence', 'Respiratory Tract Infections', 'Surveys and Questionnaires', 'Syndrom... | 26,921,252 | [['Z01.252.474.164.225', 'Z01.433.114'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406'], ['M01.060.406.448'], ['A12.459'], ['A03.556'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A grape and wine chemodiversity comparison of different appellations in Burgundy: vintage vs terroir effects. | This study aimed at assessing the ability of high resolution Fourier Transform Ion Cyclotron Resonance - Mass Spectrometry (FTICR-MS) to differentiate grapes and corresponding wines from distinct vineyards managed by a same producer, according to complex chemical fingerprints. Grape extracts (at harvest) and correspond... | ['Food Handling', 'Fruit', 'Mass Spectrometry', 'Plant Extracts', 'Vitis', 'Wine'] | 24,444,912 | [['J01.576.423.200'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['E05.196.566'], ['D20.215.784.500', 'D26.667'], ['B01.650.940.800.575.912.250.965.500'], ['G07.203.100.100.900', 'G07.203.200.887', 'J02.200.100.900', 'J02.350.887']] | ['Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Multi-charged bis(p-calixarene)/pillararene functionalized gold nanoparticles for ultra-sensitive sensing of butyrylcholinesterase. | A series of supramolecular assemblies based on multi-charged calixarene (SC4A), bis(p-calixarene) (BSC4A) and pillararene (CP5A) modified gold nanoparticles (AuNP) was constructed to realize colorimetric sensing of both succinylcholine (SuCh) and butyrylcholinesterase (BChE). With the high binding affinity of BSC4A and... | ['Biosensing Techniques', 'Butyrylcholinesterase', 'Calixarenes', 'Colorimetry', 'Coloring Agents', 'Gold', 'Hydrogen-Ion Concentration', 'Kinetics', 'Metal Nanoparticles', 'Succinylcholine', 'Surface Properties'] | 31,613,305 | [['E05.601.043'], ['D08.811.277.352.100.170.250'], ['D04.345.025'], ['E05.196.922.250'], ['D27.720.233'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['J01.637.512.600.500'], ['D02.092.877.883.333.780', 'D02.241.081.337.759.875', 'D02.675.276.232.780'], ['G02.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Massage therapy services for healthcare: a telephone focus group study of drivers for clients' continued use of services. | OBJECTIVE: To explore opinions of why clients use, value and continue to seek massage therapy as a healthcare option.DESIGN: Telephone focus group methodology was used. Current and repeat users (n = 19) of either relaxation, remedial or sports massage therapy services participated in three telephone focus groups. Audio... | ['Adolescent', 'Adult', 'Appointments and Schedules', 'Female', 'Focus Groups', 'Humans', 'Interviews as Topic', 'Male', 'Massage', 'Middle Aged', 'New Zealand', 'Patient Acceptance of Health Care', 'Social Conformity', 'Treatment Outcome', 'Young Adult'] | 19,942,108 | [['M01.060.057'], ['M01.060.116'], ['N04.452.095'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['E02.190.599.750.750', 'E02.779.867.880.750', 'E02.831.535.867.88... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Acute crystal deposition arthritis of the pubic symphysis. | A 68-year-old woman presented with an acute onset of lower abdominal pain. A CT scan of the pelvis showed acute crystal deposition arthritis, and her symptoms markedly reduced with non-steroidal anti-inflammatory drugs. Further, a radiographic evaluation of the right knee joint and CT of the cervical spine revealed cal... | ['Abdominal Pain', 'Aged', 'Anti-Inflammatory Agents, Non-Steroidal', 'Cervical Vertebrae', 'Chondrocalcinosis', 'Female', 'Humans', 'Knee Joint', 'Pubic Symphysis', 'Tomography, X-Ray'] | 23,595,192 | [['C23.888.592.612.054', 'C23.888.821.030'], ['M01.060.116.100'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['A02.835.232.834.151'], ['C05.550.114.264', 'C05.550.354.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['A02.835.583.656'], ['E01.370.350.7... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Morphological and biochemical studies on the effect of agents with liver protecting properties. | The liver protective effect of Aicaphosphate in CC1(4)-induced acute, as well as CC1(4)-and thioacetamide-induced subacute and chronic liver damages is demonstrated. The effect of the protective drugs was studied in the forms of pre-, simultaneous and delayed treatment in acute and chronic liver damages induced by vari... | ['Acetamides', 'Aminoimidazole Carboxamide', 'Animals', 'Carbon Tetrachloride Poisoning', 'Disease Models, Animal', 'Female', 'Imidazoles', 'Liver', 'Liver Cirrhosis, Experimental', 'Male', 'Rats', 'Thioacetamide'] | 729,706 | [['D02.065.064', 'D02.241.081.018.110'], ['D03.383.129.308.030'], ['B01.050'], ['C25.723.177'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D03.383.129.308'], ['A03.620'], ['C06.552.630.467', 'C23.550.355.412.467', 'E05.598.500.468'], ['B01.050.150.900.649.313.992.635.505.700'], ['D02.065.064.786', 'D02.065.900.89... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effectiveness of Nivolumab versus Docetaxel as Second-Line Treatment in Non-Small Cell Lung Cancer Patients in Clinical Practice. | AIMS: To evaluate the effectiveness of nivolumab as second-line treatment compared to standard therapy with docetaxel in adult patients with non-small cell lung cancer (NSCLC) in clinical practice.METHODS: This is an observational, retrospective cohort study of adult patients diagnosed with NSCLC, stage III-IV, treated... | ['Aged', 'Antibodies, Monoclonal', 'Antineoplastic Agents', 'Carcinoma, Non-Small-Cell Lung', 'Disease-Free Survival', 'Docetaxel', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Nivolumab', 'Proportional Hazards Models', 'Retrospective Studies', 'Taxoids', 'T... | 29,045,938 | [['M01.060.116.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D27.505.954.248'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Additional surgical resection after endoscopic mucosal dissection for early gastric cancer: A medium-sized hospital's experience. | PURPOSE: In Japan, the majority of early gastric cancers (EGCs) are now treated with endoscopic submucosal dissection (ESD). Patients with non-curative lesions treated by ESD are advised to undergo additional surgical resection (ASR) based on guidelines from the Japan Gastroenterological Endoscopy Society (JGES) and Ja... | ['Aged', 'Early Detection of Cancer', 'Endoscopic Mucosal Resection', 'Female', 'Gastrectomy', 'Gastric Mucosa', 'Humans', 'Japan', 'Lymphatic Metastasis', 'Male', 'Neoplasm, Residual', 'Practice Guidelines as Topic', 'Retrospective Studies', 'Stomach Neoplasms', 'Unnecessary Procedures'] | 27,871,804 | [['M01.060.116.100'], ['E01.390.500'], ['E01.370.372.250.250.250', 'E01.370.388.250.250.250.230', 'E04.210.240.250.230', 'E04.502.250.250.250.230'], ['E04.210.419'], ['A03.556.875.875.440', 'A10.615.550.291'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['C04.697.650.560', 'C23.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Protective role for plasmid DNA-mediated VIP gene transfer in non-obese diabetic mice. | Studies focused on the development of diabetes in NOD mice-a model for human type 1 diabetes-have revealed that an autoimmune inflammatory process is produced by the effect of Th1 cells and their secreted cytokines. DNA vaccination has been shown to be an effective method for modulating immunity in viral infections and... | ['Animals', 'Diabetes Mellitus', 'Female', 'Gene Transfer Techniques', 'Mice', 'Mice, Inbred NOD', 'Plasmids', 'Vasoactive Intestinal Peptide'] | 16,888,188 | [['B01.050'], ['C18.452.394.750', 'C19.246'], ['E05.393.350'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.565', 'B01.050.150.900.649.313.992.635.505.500.400.565'], ['G05.360.600'], ['D06.472.317.950', 'D06.472.699.952', 'D12.644.400.875', 'D12.644.548.952', 'D12.776.631.650.875']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-performance capillary electrophoresis of proteins. Sodium dodecyl sulphate-polyacrylamide gel-filled capillary column for the determination of recombinant biotechnology-derived proteins. | Fused-silica capillary columns were filled with sodium dodecyl sulfate-polyacrylamide gel and the column effluent was monitored at 214 nm using a commercially available high-performance capillary electrophoresis (HPCE) instrument to separate and rapidly quantify recombinant biotechnology-derived proteins. An excellent ... | ['Animals', 'Carbonic Anhydrases', 'Cattle', 'Chickens', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Molecular Weight', 'Muramidase', 'Myosins', 'Ovalbumin', 'Phosphorylase b', 'Rabbits', 'Recombinant Proteins', 'Serum Albumin, Bovine', 'Sodium Dodecyl Sulfate', 'Trypsin Inhibitors', 'beta-Galactosidase... | 1,774,236 | [['B01.050'], ['D08.811.520.241.300.150'], ['B01.050.150.900.649.313.500.380.271'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.401.402', 'E05.301.300.319'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.494'], ['D08.811.277.450.642'], ['D05.750.078.730.475', 'D08.811.277.0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Building capacity for active surveillance of vaccine adverse events in the Americas: A hospital-based multi-country network. | New vaccines designed to prevent diseases endemic in low and middle-income countries are being introduced without prior utilization in countries with robust vaccine pharmacovigilance systems. Our aim was to build capacity for active surveillance of vaccine adverse events in the Americas. We describe the implementation ... | ['Americas', 'Capacity Building', 'Drug-Related Side Effects and Adverse Reactions', 'Epidemiological Monitoring', 'Hospitals', 'Humans', 'International Cooperation', 'Measles-Mumps-Rubella Vaccine', 'Meningitis, Aseptic', 'Proof of Concept Study', 'Purpura, Thrombocytopenic, Idiopathic', 'Retrospective Studies', 'Worl... | 28,803,714 | [['Z01.107'], ['N02.138', 'N04.452.105'], ['C25.100'], ['E05.318.375', 'N06.850.520.460'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615.500'], ['D20.215.894.815.500', 'D20.215.894.899.404.500', 'D20.215.894.899.488.500', 'D20.215.894.899.779.500'], ['C10.228.614.220'], ['H01.770.644.578']... | ['Geographicals [Z]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
The practice and perception of intensive care staff using the closed suctioning system. | Tracheobronchial suctioning using the closed suctioning system (CSS) has physiological benefits for critically ill patients. Despite these benefits, nurses have raised concerns about the CSS. The aims of this study were to identify concerns, count how frequently they occurred and examine the relationship between the co... | ['Bronchi', 'Clinical Competence', 'Critical Illness', 'Humans', 'Intensive Care Units', 'Northern Ireland', 'Nurses', 'Physical Therapy Modalities', 'Respiration, Artificial', 'Suction', 'Surveys and Questionnaires', 'Trachea'] | 9,840,873 | [['A04.411.125'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['C23.550.291.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['Z01.542.363.602'], ['M01.526.485.650', 'N02.360.650'], ['E02.779', 'E02.831.535'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820'], ['E04.237.890'], ['E05.3... | ['Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Combined functional electrical stimulation (FES) and robotic system for wrist rehabiliation after stroke. | Functional electrical stimulation (FES) and rehabilitation robots are techniques used to assist in post-stroke rehabilitation. However, FES and rehabilitation robots are still separate systems currently; and their combined training effects on persons after experiencing a stroke have not been well studied yet. In this w... | ['Electric Stimulation', 'Humans', 'Robotics', 'Stroke Rehabilitation', 'Wrist Injuries'] | 20,543,302 | [['E05.723.402'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630'], ['E02.760.169.063.500.477.500', 'E02.831.477.500', 'H02.403.680.600.750.500', 'N02.421.784.511.500'], ['C26.088.906']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Elevated hypothalamic beacon gene expression in Psammomys obesus prone to develop obesity and type 2 diabetes. | OBJECTIVE: To investigate hypothalamic beacon gene expression at various developmental stages in genetically selected diabetes-resistant and diabetes-prone Psammomys obesus. In addition, effects of dietary energy composition on beacon gene expression were investigated in diabetes-prone P. obesus.METHODS: Hypothalamic b... | ['Aging', 'Animals', 'Body Weight', 'Diabetes Mellitus, Type 2', 'Diet', 'Energy Intake', 'Gene Expression', 'Genetic Predisposition to Disease', 'Gerbillinae', 'Hypothalamus', 'Insulin', 'Nerve Tissue Proteins', 'Obesity', 'Polymerase Chain Reaction', 'Proteins', 'Ubiquitins'] | 12,032,742 | [['G07.345.124'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C18.452.394.750.149', 'C19.246.300'], ['G07.203.650.240'], ['G07.203.650.240.340'], ['G05.297'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.992.635... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of a high temperature-atmospheric pressure environmental cell for high-resolution TEM. | An environmental cell for high-temperature, high-resolution transmission electron microscopy of nanomaterials in near atmospheric pressures is developed. The developed environmental cell is a side-entry type with built-in specimen-heating element and micropressure gauge. The relationship between the cell condition and ... | ['Atmospheric Pressure', 'Cytological Techniques', 'Hot Temperature', 'Image Processing, Computer-Assisted', 'Microscopy, Electron, Transmission', 'Nanostructures', 'Silicon Compounds', 'Specimen Handling'] | 21,427,119 | [['G16.500.750.274', 'N06.230.300.100.185'], ['E01.370.225.500', 'E05.200.500', 'E05.242'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['L01.224.308'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['J01.637.512'], ['D01.837... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
The Frontalis Activity Measurement Standard: a novel contralateral method for assessing botulinum neurotoxin type-A activity. | BACKGROUND: There are conflicting data regarding the specific attributes of botulinum neurotoxin type-A (BoNTA) products including onset of action, duration and spread because accurate, objective methods for assessing their clinical activity are lacking.OBJECTIVE: To refine definitions for BoNTA activity utilizing the ... | ['Botulinum Toxins, Type A', 'Double-Blind Method', 'Facial Muscles', 'Forehead', 'Humans', 'Neuromuscular Agents', 'Treatment Outcome'] | 22,052,264 | [['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['A02.633.567.400', 'A14.363'], ['A01.456.505.580'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Production of a low calorie mandarin juice by enzymatic conversion of constituent sugars to oligosaccharides and prevention of insoluble glucan formation. | Over 99% of sucrose in mandarin juice (57.1 g/l in original juice to 428.4 g/l in concentrated juice) was enzymatically converted to glucooligosaccharides using 3 U dextransucrase/ml prepared from Leuconostoc mesenteroides at 28 °C. The oligosaccharide synthesis yields were 51 and 47% for the original and the concentra... | ['Beverages', 'Calorimetry', 'Food Handling', 'Glucosyltransferases', 'Leuconostoc', 'Oligosaccharides', 'Streptococcus mutans', 'Sucrase', 'Sucrose', 'Temperature'] | 25,381,596 | [['G07.203.100', 'J02.200'], ['E05.196.131'], ['J01.576.423.200'], ['D08.811.913.400.450.460'], ['B03.353.750.475.450', 'B03.510.550.475.450'], ['D09.698.629'], ['B03.353.750.737.872.875.520', 'B03.510.400.800.872.875.520', 'B03.510.550.737.872.875.520'], ['D08.811.277.450.329.738'], ['D09.698.629.305.770', 'D09.947.75... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Drug-eluting stent treatment of a radiation-induced left internal mammary arterial graft stenosis. | A 62-year-old man underwent radiotherapy to the left upper chest for treatment of Pancoast syndrome on a background of previous coronary artery bypass grafting 12 years earlier. Within 1 year, he developed significant stenoses of both the left internal mammary artery (LIMA) graft and ostial left vertebral artery, presu... | ['Angioplasty, Balloon, Coronary', 'Coronary Angiography', 'Coronary Artery Bypass', 'Drug-Eluting Stents', 'Graft Occlusion, Vascular', 'Humans', 'Male', 'Middle Aged', 'Pancoast Syndrome', 'Radiation Injuries'] | 18,787,292 | [['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['E04.100.376.719.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Environmental health risks and benefits of the use of mosquito coils as malaria prevention and control strategy. | BACKGROUND: Malaria is an infectious disease that causes many deaths in sub-Saharan Africa. In resource-poor malaria endemic communities, mosquito coils are commonly applied in households to repel the vector mosquito that transmits malaria parasites. In applying these coils, users have mainly been interested in the env... | ['Air Pollution, Indoor', 'Animals', 'Anopheles', 'Environmental Health', 'Humans', 'Insect Repellents', 'Insecticides', 'Malaria', 'Mosquito Control', 'Mosquito Vectors', 'Risk Assessment'] | 30,012,143 | [['N06.850.460.100.080'], ['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['H02.229'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.706.434', 'D27.720.031.700.441', 'D27.888.723.441'], ['D27.720.031.700.491', 'D27.888.723.491'], ['C01.610.752.530', 'C01.920.875'], ['N06.850.780.2... | ['Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Mutuality and preparedness moderate the effects of caregiving demand on cancer family caregiver outcomes. | BACKGROUND: Family caregiving researchers have explored the moderating or stress-buffering effects of variables such as coping and social support. However, the quality of the family caregiver-patient relationship and preparedness for caregiving have received little attention as potential moderators.OBJECTIVE: To explor... | ['Adaptation, Psychological', 'Adult', 'Aged', 'Aged, 80 and over', 'Caregivers', 'Family Relations', 'Female', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasms', 'Regression Analysis', 'Social Support', 'United States'] | 18,004,189 | [['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['F01.829.263.370', 'I01.880.853.150.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['C... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Cigarette smoking in the U.S. military: findings from the 1992 Worldwide Survey. | BACKGROUND: Using data from the military's Worldwide Survey series, this article presents findings on the prevalence of smoking among active-duty military personnel in 1992 and trends since 1980.METHODS: A stratified probability sampling design was used in the 1992 Worldwide Survey. Military installations worldwide wer... | ['Adult', 'Data Collection', 'Demography', 'Female', 'Humans', 'Male', 'Military Personnel', 'Probability', 'Regression Analysis', 'Sampling Studies', 'Smoking', 'Smoking Cessation', 'United States'] | 7,971,881 | [['M01.060.116'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.625'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600'], ['E05.318.740.750', 'N05.715.360.750.695', 'N... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Control of vascular smooth muscle cell growth in fowl. | In adult domestic fowl, angiotensin (ANG) receptors are present in the vascular smooth muscles (VSM) and in the endothelium, mediating vasorelaxation via endothelium-derived relaxing factor/cGMP. ANG II-induced relaxation is minor in chicks and becomes more marked as they mature but diminishes in adult birds, whereas A... | ['Anesthesia', 'Angiotensin II', 'Animals', 'Aorta', 'Cell Division', 'Cells, Cultured', 'Chickens', 'Cyclic GMP', 'DNA', 'Fetal Blood', 'Homeostasis', 'Muscle, Smooth, Vascular', 'Norepinephrine', 'Penicillamine', 'Platelet-Derived Growth Factor'] | 9,748,410 | [['E03.155'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['A07.015.114.056'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['B01.050.150.900.248.350.150', 'B01.050.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interactions of serotoninergic, cholinergic, and tachykinin-containing nerve elements in the rabbit small intestine. | This report presents novel results on the effects of serotonin (5-HT) on longitudinal muscle contractions in the rabbit ileum and the interactions of serotonin with some neuronal elements of the myenteric plexus. We showed previously that serotonin-triggered contractions involved two mechanisms in the rabbit ileum: neu... | ['Animals', 'Cholinergic Fibers', 'Excitation Contraction Coupling', 'Female', 'Gastrointestinal Motility', 'Ileum', 'In Vitro Techniques', 'Male', 'Myenteric Plexus', 'Neurons', 'Rabbits', 'Receptors, Serotonin', 'Serotonin', 'Tachykinins'] | 19,685,504 | [['B01.050'], ['A08.675.127.500', 'A08.675.542.234', 'A11.671.188.500', 'A11.671.501.234'], ['G02.111.820.800.100.500', 'G04.835.199', 'G11.427.494.235'], ['G10.261.360'], ['A03.556.124.684.249', 'A03.556.249.124'], ['E05.481'], ['A08.800.050.050.500', 'A08.800.050.150.500', 'A08.800.800.060.500'], ['A08.675', 'A11.671... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of rearranged T cell receptor (TCR) V beta transcripts in livers of primary biliary cirrhosis: preferential V beta usage suggests antigen-driven selection. | The presence of autoantibodies to mitochondrial pyruvate dehydrogenase complex-E2 (PDC-E2) and self-reactive T cells to PDC suggests that autoimmune mechanisms may be involved in the pathogenesis of primary biliary cirrhosis (PBC). Molecular analysis of intrahepatic TCR repertoire may provide valuable information on a ... | ['Amino Acid Sequence', 'Base Sequence', 'Conserved Sequence', 'Female', 'Gene Rearrangement, beta-Chain T-Cell Antigen Receptor', 'Humans', 'Immunoglobulin Joining Region', 'Interferon-gamma', 'Interleukin-2', 'Interleukin-4', 'Liver Cirrhosis, Biliary', 'Middle Aged', 'Molecular Sequence Data', 'Multigene Family', 'P... | 8,565,296 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.580'], ['G05.344.801.211', 'G12.500.287.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.541.500.650.500.590', 'D12.776.124.486.485.680.650.500.590', 'D12.776.124.486.485.797.590', 'D12... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Pathogenic importance of fibronectin in the superficial region of articular cartilage as a local factor for the induction of pannus extension on rheumatoid articular cartilage. | To identify the local factors in cartilage that are responsible for the induction of pannus invasion, a 14 day organ culture study in which rheumatoid synovium was grown in contact with cartilage pieces was carried out. Rheumatoid synovium preferentially extended over hyaluronidase treated cartilage pieces, but detache... | ['Arthritis, Rheumatoid', 'Cartilage, Articular', 'Cell Adhesion', 'Cells, Cultured', 'Exudates and Transudates', 'Fibronectins', 'Humans', 'Oligopeptides', 'Organ Culture Techniques', 'Synovial Membrane'] | 1,632,660 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['A02.165.407.150', 'A02.835.583.192'], ['G04.022'], ['A11.251'], ['A12.383'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.456'], ['E05.481.... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Computed tomographic evaluation of elbow congruity during arthroscopy in a canine cadaveric model. | OBJECTIVE: To assess the effect of arthroscope insertion, using a carbon-fibre rod model, on humero-radial, humero-ulnar and radio-ulnar congruity, as assessed by computed tomography (CT).METHODS: Cadaveric Greyhound elbow joints were assessed at a flexion angle of 135 ± 5° using CT. For condition 1, a 36 mm fulcrum in... | ['Animals', 'Arthrography', 'Arthroscopy', 'Dogs', 'Forelimb', 'Humerus', 'Joints', 'Tomography, X-Ray Computed', 'Ulna'] | 25,487,317 | [['B01.050'], ['E01.370.350.700.070'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['B01.050.150.900.649.313.750.250.216.200'], ['A13.395'], ['A02.835.232.087.090.400'], ['A02.835.583'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Risk factors for peptic ulcer disease in renal transplant patients--11 years of experience from a single center. | BACKGROUND: Peptic ulcer disease is a common complication among renal transplant recipients and causes significant morbidity and mortality.METHODS: From 1990 through 2000, 465 renal transplant patients were followed-up in our institute. Most patients received corticosteroids and cyclosporine-based immunosuppressive reg... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anti-Ulcer Agents', 'Chi-Square Distribution', 'Female', 'Humans', 'Immunosuppressive Agents', 'Incidence', 'Kidney Transplantation', 'Logistic Models', 'Male', 'Middle Aged', 'Peptic Ulcer', 'Prevalence', 'Risk Factors'] | 15,267,008 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.483.203'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['E05.318.308.985.525.375', 'N01.224.935.597.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Near-infrared molecular imaging of tumors via chemokine receptors CXCR4 and CXCR7. | The chemokine CXCL12/SDF-1 and its receptors CXCR4 and CXCR7 play a major role in tumor invasion, proliferation and metastasis. Since both receptors are overexpressed on distinct tumor cells and on the tumor vasculature, we evaluated their potential as targets for detection of cancers by molecular imaging. We synthesiz... | ['Animals', 'Breast Neoplasms', 'Cattle', 'Chemokine CXCL12', 'Female', 'Fluorescent Dyes', 'Glioma', 'Humans', 'Image Processing, Computer-Assisted', 'Mice', 'Mice, Nude', 'Receptors, CXCR', 'Receptors, CXCR4', 'Serum Albumin, Bovine', 'Spectroscopy, Near-Infrared', 'Tumor Cells, Cultured'] | 21,735,100 | [['B01.050'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.500.380.271'], ['D12.644.276.374.200.120.600', 'D12.776.467.374.200.120.600', 'D23.125.300.120.600', 'D23.469.200.120.600', 'D23.529.374.200.120.600'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['C04.557.465.625.600.380', 'C04.557.470.670... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Evaluation of morphological parameters of blood platelets in the course of giardiasis]. | UNLABELLED: Blood platelets play an important role in defensive mechanisms of the organism, especially in anti-parasitic immunity. Parasites activate the blood platelets in the peripheral blood and this activation may be expressed in changes of their morphological parameters.MATERIAL AND METHODS: We have conducted our ... | ['Adult', 'Aged', 'Blood Platelets', 'Female', 'Giardiasis', 'Humans', 'Male', 'Middle Aged', 'Platelet Activation'] | 19,205,377 | [['M01.060.116'], ['M01.060.116.100'], ['A11.118.188', 'A15.145.229.188'], ['C01.610.432.481', 'C01.610.752.400', 'C06.405.469.452.481'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G09.188.390.600']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Alteration in the level of interferon-gamma results in acceleration of Theiler's virus-induced demyelinating disease. | Intracerebral (i.c.) inoculation of susceptible strains of mice with Theiler's murine encephalomyelitis virus (TMEV) results in immune-mediated demyelination. We examined the role of interferon (IFN)-gamma in this virally induced pathogenesis. Intraperitoneal (i.p.) injection of susceptible mice with an IFN-gamma-neutr... | ['Animals', 'Antibodies, Monoclonal', 'Antibodies, Viral', 'Demyelinating Diseases', 'Female', 'Hypersensitivity, Delayed', 'Interferon-gamma', 'Mice', 'T-Lymphocytes', 'Theilovirus'] | 7,829,664 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['C10.314'], ['C20.543.418'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK. | The Tax oncoprotein of human T-cell leukaemia virus type I (HTLV-I) persistently activates nuclear factor-kappaB (NF-kappaB), which is required for HTLV-I-mediated T-cell transformation. Tax activates NF-kappaB by stimulating the activity of IkappaB kinase (IKK), but the underlying mechanism remains elusive. Here, we s... | ['Animals', 'Cell Line', 'Cell Line, Transformed', 'Gene Products, tax', 'Human T-lymphotropic virus 1', 'Humans', 'I-kappa B Kinase', 'Mice', 'NF-kappa B'] | 17,363,973 | [['B01.050'], ['A11.251.210'], ['A11.251.210.172'], ['D12.776.624.664.520.750.480', 'D12.776.964.700.750.480', 'D12.776.964.775.750.480', 'D12.776.964.925.984.410'], ['B04.613.807.200.725.400', 'B04.820.650.200.725.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.494', 'D12.644.360.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biaxial mechanical properties of bovine jugular venous valve leaflet tissues. | Venous valve incompetence has been implicated in diseases ranging from chronic venous insufficiency (CVI) to intracranial venous hypertension. However, while the mechanical properties of venous valve leaflet tissues are central to CVI biomechanics and mechanobiology, neither stress-strain curves nor tangent moduli have... | ['Animals', 'Biomechanical Phenomena', 'Cattle', 'Collagen', 'Elastic Modulus', 'Jugular Veins', 'Stress, Mechanical', 'Venous Valves'] | 28,631,145 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.500.380.271'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G01.374.590.605'], ['A07.015.908.498'], ['G01.374.835'], ['A07.015.908.950']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Survival-apoptosis associated signaling in GNE myopathy-cultured myoblasts. | GNE Myopathy (GNEM) is a neuromuscular disorder caused by mutations in the GNE gene. It is a slowly progressive distal and proximal muscle weakness sparing the quadriceps. In this study, we applied our model of mutated M743T GNE enzyme skeletal muscle-cultured myoblasts and paired healthy controls to depict the pattern... | ['Adult', 'Apoptosis', 'Case-Control Studies', 'Cell Survival', 'Cells, Cultured', 'Distal Myopathies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Multienzyme Complexes', 'Mutant Proteins', 'Mutation', 'Myoblasts, Skeletal', 'PTEN Phosphohydrolase', 'Phosphatidylinositol 3-Kinases', 'Protein-Serine-Threonine Kinases',... | 25,510,413 | [['M01.060.116'], ['G04.146.954.035'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G04.346'], ['A11.251'], ['C05.651.534.500.074', 'C10.668.491.175.500.074', 'C16.320.577.074'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D05.500.562', 'D08.811.600'], ['D... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Genome-wide analysis of abnormal H3K9 acetylation in cloned mice. | Somatic nuclear transfer is a cloning technique that shows great promise in the application to regenerative medicine. Although cloned animals are genetically identical to their donor counterparts, abnormalities in phenotype and gene expression are frequently observed. One hypothesis is that the cause of these abnormali... | ['Acetylation', 'Animals', 'Chromatin Immunoprecipitation', 'Cloning, Molecular', 'Epigenesis, Genetic', 'Gene Expression Regulation', 'Genome', 'Histones', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred DBA', 'Models, Genetic', 'Phenotype', 'Polymerase Chain Reaction', 'Promoter Regions, Genetic'] | 18,398,451 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.050'], ['E05.393.170', 'E05.478.605.160'], ['E05.393.220'], ['G05.308.203'], ['G05.308'], ['G05.360.340'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.05... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Significance of postgamma protein fraction in tears. | Tear protein electrophoresis identifies three principal groups of proteins designated as fast-migrating proteins, globulins and postgamma protein fraction. Postgamma fraction represents 32% of total tear protein content and is antigenically constituted by lysozyme as a unique component. The clinical usefulness of deter... | ['Adult', 'Cystatin C', 'Cystatins', 'Electrophoresis, Cellulose Acetate', 'Humans', 'Muramidase', 'Proteins', 'Tears'] | 3,822,396 | [['M01.060.116'], ['D12.776.215.300'], ['D12.776.215'], ['E05.196.401.200', 'E05.301.300.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.450.642'], ['D12.776'], ['A12.200.882']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The infratemporal fossa oncological surgery]. | INTRODUCTION: The infratemopral fossa pathology cases are very rare. They grow unnoticed for considerable period until there are some impairments of function of the anatomical structures of the place. Aim. The aim of the paper was to recollect the information about rare cases the pathological state of the area in commo... | ['Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Skull Base', 'Skull Base Neoplasms', 'Tomography, X-Ray Computed', 'Treatment Outcome', 'Zygoma'] | 18,837,218 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['A01.456.830', 'A02.835.232.781.750'], ['C04.588.149.721.828', 'C05.116.231.754.829'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.8... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Benzo[b]thiophene-2-carboxamides and benzo[b]furan-2-carboxamides are potent antagonists of the human H3-receptor. | Benzo[b]thiophene-2-carboxamides and benzo[b]furan-2-carboxamides have been found to be antagonists on the human histamine-3-receptor, showing a Ki value of as low as 4 nM. | ['Amides', 'Benzene', 'Furans', 'Histamine Antagonists', 'Humans', 'Molecular Structure', 'Receptors, Histamine H3', 'Structure-Activity Relationship', 'Thiophenes'] | 16,616,493 | [['D02.065'], ['D02.455.426.559.389.023'], ['D03.383.312'], ['D27.505.519.625.375.425', 'D27.505.696.577.375.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570', 'G02.466'], ['D12.776.543.750.670.450.500', 'D12.776.543.750.720.480.500'], ['G02.111.830', 'G07.690.773.997'], ['D02.886.778', 'D03.383.90... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Concentrations of some heavy metals in commercially important finfish and shellfish of the River Ganga. | Heavy metals are dangerous to aquatic organisms and it can be bioaccumulated in the food chain leading to diseases in human. Cumulative effects of metals or chronic poisoning may occur as a result of long-term exposure even to low concentrations. The accumulation of heavy metals varies depending upon the species, envir... | ['Animals', 'Fishes', 'India', 'Metals, Heavy', 'Rivers', 'Shellfish', 'Water Pollutants, Chemical'] | 21,660,552 | [['B01.050'], ['B01.050.150.900.493'], ['Z01.252.245.393'], ['D01.268.556', 'D01.552.544'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['G07.203.300.600.875.700', 'J02.500.600.875.700'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Eye movement baseline oscillation and variability of eye position during foveation in congenital nystagmus. | Despite the inability to maintain steady fixation, congenital nystagmus does not necessarily reduce visual acuity, that can be achieved during the foveation periods. The duration of the foveation period, but also the cycle-to-cycle variability of eye position and velocity during foveations play an important role. A qua... | ['Adolescent', 'Adult', 'Child', 'Eye', 'Eye Movements', 'Female', 'Fovea Centralis', 'Humans', 'Male', 'Nystagmus, Congenital', 'Oscillometry', 'Visual Acuity'] | 14,661,903 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['A01.456.505.420', 'A09.371'], ['G11.427.410.140', 'G14.350'], ['A09.371.729.522.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.292.562.675.300', 'C11.590.400.300', 'C16.614.643'], ['E05.654'], ['E01.370.380.850.950', 'F02.463.593.932.901', 'G14.940']] | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The Efficacy of Concurrent or Sequential Intravenous and Intratympanic Steroid for Idiopathic Sudden Sensorineural Hearing Loss. | OBJECTIVE: The purpose of this retrospective study was to investigate the difference in treatment outcomes for patients with idiopathic sudden sensorineural hearing loss (SSNHL) undergoing concurrent or sequential intravenous (IV) and intratympanic (IT) steroid therapies.METHODS: Patients with idiopathic SSNHL admitted... | ['Adult', 'Aged', 'Audiometry, Pure-Tone', 'Dexamethasone', 'Female', 'Glucocorticoids', 'Hearing Loss, Sensorineural', 'Hearing Loss, Sudden', 'Humans', 'Injection, Intratympanic', 'Male', 'Middle Aged', 'Retrospective Studies', 'Treatment Outcome', 'Tympanic Membrane'] | 30,537,751 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.382.375.060.055'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.888.592.763.393.341.887'], ['C09.218.458.341.900', 'C10.597.751.418.341.900', 'C23.888.592.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Divergence in sex steroid hormone signaling between sympatric species of Japanese threespine stickleback. | Sex steroids mediate the expression of sexually dimorphic or sex-specific traits that are important both for mate choice within species and for behavioral isolation between species. We investigated divergence in sex steroid signaling between two sympatric species of threespine stickleback (Gasterosteus aculeatus): the ... | ['Animals', 'Female', 'Gonadal Steroid Hormones', 'Male', 'Polymerase Chain Reaction', 'Signal Transduction', 'Smegmamorpha', 'Species Specificity', 'Steroids'] | 22,216,225 | [['B01.050'], ['D06.472.334.851'], ['E05.393.620.500'], ['G02.111.820', 'G04.835'], ['B01.050.150.900.493.850'], ['G16.824'], ['D04.210.500']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Discovery of a potent series of non-steroidal non á-trifluoromethyl carbinol glucocorticoid receptor agonists with reduced lipophilicity. | A novel series of indazole non-steroidal glucocorticoid receptor agonist has been discovered. This series features a sulfonamide central core and meta amides which interact with the extended ligand binding domain. This series has produced some of the most potent and least lipophilic agonists of which we are aware such ... | ['Binding Sites', 'Cell Line, Tumor', 'Computer Simulation', 'Drug Evaluation, Preclinical', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Indazoles', 'Receptors, Glucocorticoid', 'Structure-Activity Relationship', 'Sulfonamides'] | 21,257,309 | [['G02.111.570.120'], ['A11.251.210.190', 'A11.251.860.180'], ['L01.224.160'], ['E05.290.750', 'E05.337.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.409'], ['D03.383.129.539.487', 'D03.633.100.449'], ['D12.776.826.750.430'], ['G02.111.830', 'G07.690.773.997'], ['D02.065.884', 'D02.886.590.700']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Novel scoring system using cardiopulmonary exercise testing predicts prognosis in heart failure patients receiving guideline-directed medical therapy. | BACKGROUND: Among variables obtained from cardiopulmonary exercise testing (CPXT), peak oxygen consumption (PV?O2) and the minute ventilation vs. carbon dioxide output (V?E vs. V?CO2) slope were established as predictors of death of patients with heart failure (HF) at the cutoff points of 14 ml·min(-1)·kg(-1)and 34, re... | ['Adult', 'Exercise Test', 'Female', 'Guideline Adherence', 'Heart Failure', 'Heart Rate', 'Humans', 'Male', 'Middle Aged', 'Oxygen Consumption', 'Patient Readmission', 'Predictive Value of Tests'] | 25,739,339 | [['M01.060.116'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['N04.761.337', 'N05.715.360.395'], ['C14.280.434'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G03.680'], ['E02.760.400.620', 'N02.421.585.400.620'], ['E05.318.370.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Corrosive esophageal strictures: long-term effectiveness of balloon dilation in 117 patients. | PURPOSE: To retrospectively evaluate the long-term results of balloon dilation in the treatment of corrosive esophageal strictures and to identify prognostic factors associated with clinical outcome.MATERIALS AND METHODS: From January 1987 to June 2006, balloon dilation was undertaken in 117 patients with corrosive eso... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Catheterization', 'Caustics', 'Contrast Media', 'Esophageal Stenosis', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Proportional Hazards Models', 'Recurrence', 'Retrospective Studies', 'Treatment Outcome'] | 18,440,463 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.148', 'E05.157'], ['D27.720.185', 'D27.888.569.185'], ['D27.505.259.500', 'D27.720.259'], ['C06.405.117.544'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Luteinizing hormone-releasing factor-like immunoreactivity in islet cells and insulomas of the human pancreas. | Luteinizing hormone-releasing factor (LRF)-like immunoreactivity was demonstrated by a three-layer immunoperoxidase method in the islet cells of human pancreas and in the neoplastic cells of insulomas. Adenocarcinomas originating in the exocrine pancreas were LRF-negative. The results demonstrate another hypothalamic p... | ['Adenocarcinoma', 'Adenoma, Islet Cell', 'Female', 'Gonadotropin-Releasing Hormone', 'Humans', 'Immunoenzyme Techniques', 'Male', 'Middle Aged', 'Pancreas', 'Pancreatic Neoplasms'] | 232,493 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ketamine exposure during embryogenesis inhibits cellular proliferation in rat fetal cortical neurogenic regions. | BACKGROUND: Developmental neurotoxicity of ketamine, an N-methyl-D-aspartate receptor antagonist, must be considered due to its widespread uses for sedation/analgesia/anesthesia in pediatric and obstetric settings. Dose-dependent effects of ketamine on cellular proliferation in the neurogenic regions of rat fetal corte... | ['Anesthetics, Dissociative', 'Animals', 'Brain', 'Cell Count', 'Cell Proliferation', 'Cerebral Cortex', 'Cerebral Ventricles', 'Dose-Response Relationship, Drug', 'Embryonic Development', 'Female', 'Ketamine', 'Lateral Ventricles', 'Neurogenesis', 'Pregnancy', 'Rats', 'Rats, Sprague-Dawley'] | 26,822,861 | [['D27.505.696.277.100.035.075.035', 'D27.505.954.427.210.100.035.075.035'], ['B01.050'], ['A08.186.211'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.161.750', 'G07.345.249.410.750'], ['A08.186.211.200.885.287.500'], ['A08.186.211.140'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.345... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lethality of cardiovascular events highlights the variable impact of complication type between thoracoscopic and open pulmonary lobectomies. | BACKGROUND: This study examines the impact of postoperative complications by type on perioperative mortality in lobectomies performed by thoracoscopic (video-assisted thoracoscopic surgery [VATS]) and open thoracotomy (OPEN) approaches for primary lung cancer.METHODS: A retrospective analysis of the Healthcare and Util... | ['Aged', 'Aged, 80 and over', 'Cardiovascular Diseases', 'Female', 'Hospital Mortality', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Pneumonectomy', 'Retrospective Studies', 'Thoracic Surgery, Video-Assisted', 'Thoracotomy'] | 24,370,204 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E04.620', 'E04.928.600.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pharmacokinetics of insulin aspart and glucagon in type 1 diabetes during closed-loop operation. | BACKGROUND: We assessed the pharmacokinetics of subcutaneous insulin aspart and glucagon during closed-loop operation and their relationship with body composition variables.METHODS: We retrospectively analyzed data collected from closed-loop experiments in 15 type 1 diabetes patients (age 47.1 ± 12.3 years, body mass i... | ['Adult', 'Body Composition', 'Body Mass Index', 'Diabetes Mellitus, Type 1', 'Glucagon', 'Humans', 'Hypoglycemic Agents', 'Infusions, Subcutaneous', 'Insulin Aspart', 'Metabolic Clearance Rate', 'Middle Aged', 'Retrospective Studies'] | 24,351,176 | [['M01.060.116'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of ELF capacitively coupled weak electric fields on metabolism of 6B1 cells. | In this study, we adopted several methods of MTT colorimetry, DAPI fluorimetry and ELISA to study the effects of extremely low frequency (ELF) capacitively coupled electric fields (EFs) on the metabolism of 6B1 cells. The result shows that 50 mV cm(-1) ELF EF (10-100 Hz) has no significant effect on proliferation, DNA ... | ['Cell Division', 'Cell Line', 'Colorimetry', 'Electricity', 'Enzyme-Linked Immunosorbent Assay', 'Fluorometry', 'Mitochondria', 'Succinate Dehydrogenase'] | 10,379,556 | [['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['E05.196.922.250'], ['G01.358.500.249'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E05.196.712.516.600'], ['A11.284.430.214.190.875.564', 'A11.284.835... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Everyday empathic accuracy in younger and older couples: do you need to see your partner to know his or her feelings? | On average, older adults are less accurate than younger adults at recognizing emotions from faces or voices. We challenge the view that such differences in emotion-recognition tasks reflect differences in empathic accuracy (the ability to infer other people's feelings): Empathic accuracy relies not only on sensory cues... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Aging', 'Emotions', 'Empathy', 'Female', 'Humans', 'Interpersonal Relations', 'Male', 'Recognition, Psychology', 'Sexual Partners', 'Young Adult'] | 24,013,188 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['F01.470'], ['F01.752.355', 'F01.752.543.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F02.463.425.540.706'], ['M01.778'], ['M01.060.116.815']] | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mice with a Mutation in the Mdm2 Gene That Interferes with MDM2/Ribosomal Protein Binding Develop a Defect in Erythropoiesis. | MDM2, an E3 ubiquitin ligase, is an important negative regulator of tumor suppressor p53. In turn the Mdm2 gene is a transcriptional target of p53, forming a negative feedback loop that is important in cell cycle control. It has recently become apparent that the ubiquitination of p53 by MDM2 can be inhibited when certa... | ['Amino Acid Substitution', 'Anemia, Diamond-Blackfan', 'Animals', 'Bone Marrow', 'Erythroid Cells', 'Erythropoiesis', 'Haploinsufficiency', 'Mice', 'Mice, Knockout', 'Mutation, Missense', 'Myelodysplastic Syndromes', 'Proto-Oncogene Proteins c-mdm2', 'Ribosomal Proteins', 'Ribosomes', 'Tumor Suppressor Protein p53'] | 27,042,854 | [['E05.393.420.601.035', 'G05.558.109'], ['C15.378.071.085.080.090', 'C15.378.071.750.500', 'C15.378.190.223.500.500.090', 'C16.320.077.090'], ['B01.050'], ['A15.382.216'], ['A11.443'], ['G04.152.825.414', 'G09.188.343.414'], ['G05.365.590.029.530.587', 'G05.380.350.500'], ['B01.050.150.900.649.313.992.635.505.500'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fast homogeneous assay for plasma procarboxypeptidase U. | Carboxypeptidase U (EC 3.4.17.20, CPU, TAFIa) is a novel determinant of the fibrinolytic rate. It circulates as an inactive zymogen, procarboxypeptidase U, which becomes active during the process of coagulation. We developed a high throughput method on microtiter plates for the determination of the procarboxypeptidase ... | ['Adult', 'Aged', 'Amidohydrolases', 'Carboxypeptidase B2', 'Enzyme Activation', 'Female', 'Fibrinolysis', 'Hippurates', 'Humans', 'Male', 'Middle Aged', 'Reference Values', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Thrombin', 'Thrombomodulin'] | 11,601,677 | [['M01.060.116'], ['M01.060.116.100'], ['D08.811.277.087'], ['D08.811.277.656.350.245.125', 'D08.811.277.656.350.555.225', 'D08.811.277.656.675.555.225', 'D08.811.277.656.837.092'], ['G02.111.263', 'G03.328'], ['G09.188.390.150.390'], ['D02.065.277.431', 'D02.241.223.100.100.400', 'D02.241.755.360', 'D02.455.426.559.38... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Differential cytokine expression by human dendritic cells in response to different Porphyromonas gingivalis capsular serotypes. | AIM: Capsular polysaccharides play an important role in the virulence of Gram-positive and Gram-negative bacteria. In Porphyromonas gingivalis, six serotypes have been described based on capsular antigenicity and its pathogenicity has been correlated both in vitro and in animal models. This study aimed to investigate t... | ['Antigens, Bacterial', 'Bacterial Capsules', 'Cells, Cultured', 'Cytokines', 'Dendritic Cells', 'Humans', 'Interferon-gamma', 'Interleukin-10', 'Interleukin-12', 'Interleukin-12 Subunit p35', 'Interleukin-12 Subunit p40', 'Interleukin-13', 'Interleukin-1beta', 'Interleukin-2', 'Interleukin-5', 'Interleukin-6', 'Lympho... | 19,682,172 | [['D23.050.161'], ['A20.186'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Student anxiety in introductory biology classrooms: Perceptions about active learning and persistence in the major. | Many researchers have called for implementation of active learning practices in undergraduate science classrooms as one method to increase retention and persistence in STEM, yet there has been little research on the potential increases in student anxiety that may accompany these practices. This is of concern because ex... | ['Anxiety', 'Biology', 'Educational Measurement', 'Female', 'Humans', 'Male', 'Problem-Based Learning', 'Students', 'Surveys and Questionnaires'] | 28,771,564 | [['F01.470.132'], ['H01.158.273'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.720', 'I02.158.660', 'I02.903.565'], ['M01.848'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Dynamic measurement of the viscoelastic properties of skin. | A wave propagation technique was used to measure the dynamic viscoelastic properties of excised skin when subjected to a low incremental strain. The propagation velocity, attenuation, and storage and loss moduli were determined from measured characteristics of a pulse propagating along a strip of skin. Experiments were... | ['Animals', 'Elasticity', 'Humans', 'In Vitro Techniques', 'Rabbits', 'Reference Values', 'Skin Physiological Phenomena', 'Stress, Mechanical', 'Viscosity'] | 2,037,615 | [['B01.050'], ['G01.374.590'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['B01.050.150.900.649.313.968.700'], ['E05.978.810'], ['G13.750'], ['G01.374.835'], ['G02.930']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Changing a conserved amino acid in R2R3-MYB transcription repressors results in cytoplasmic accumulation and abolishes their repressive activity in Arabidopsis. | Sub-group 4 R2R3-type MYB transcription factors, including MYB3, MYB4, MYB7 and MYB32, act as repressors in phenylpropanoid metabolism. These proteins contain the conserved MYB domain and the ethylene-responsive element binding factor-associated amphiphilic repression (EAR) repression domain. Additionally, MYB4, MYB7 a... | ['Arabidopsis', 'Arabidopsis Proteins', 'Gene Expression Regulation, Plant', 'Plants, Genetically Modified', 'Point Mutation', 'Repressor Proteins', 'Transcription, Genetic'] | 26,332,741 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G05.308.375'], ['B01.650.520', 'B05.620.600'], ['G05.365.590.675'], ['D12.776.260.703', 'D12.776.930.780'], ['G02.111.873', 'G05.297.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of the DNA replication velocity on the response of Salmonella typhimurium to mild heating. | Changes in the DNA replication velocity of Salmonella typhimurium following mild heat stress (52 degrees C) were studied independently of the major physiological parameter of growth rate, using thymine-requiring mutant strains derived from Salm. typhimurium LT2. The isolated mutant strains BM1 or BM2, grown either as b... | ['Culture Media', 'DNA Replication', 'DNA, Bacterial', 'Hot Temperature', 'Salmonella typhimurium', 'Thymidine'] | 2,179,199 | [['D27.720.470.305', 'E07.206'], ['G02.111.225', 'G05.226'], ['D13.444.308.212'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B03.440.450.425.800.200.825', 'B03.660.250.150.710.160.760'], ['D03.383.742.680.705', 'D13.570.230.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Characterization and overproduction of EcoO109I methyltransferase. | In order to characterize EcoO109I methyltransferase, a recombinant Escherichia coli clone that overproduces the enzyme was constructed. The coding region of M.EcoO109I was joined to the lac promoter of an expression vector, pUC118, and the resulting plasmid was introduced into E. coli HB101. M.EcoO109I was purified hom... | ['Base Sequence', 'Binding Sites', 'Cloning, Molecular', 'DNA Methylation', 'DNA, Bacterial', 'Deoxyribonucleases, Type II Site-Specific', 'Escherichia coli', 'Hydrogen-Ion Concentration', 'Plasmids', 'Recombinant Proteins', 'Substrate Specificity'] | 11,791,726 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['E05.393.220'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D13.444.308.212'], ['D08.811.150.280.260', 'D08.811.277.352.335.350.300.260', 'D08.811.277.352.355.325.300.260'], ['B03.440.450.425.325.300', 'B03.660... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
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