Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Extracellular protons accelerate hERG channel deactivation by destabilizing voltage sensor relaxation. | hERG channels underlie the delayed-rectifier K+ channel current (IKr), which is crucial for membrane repolarization and therefore termination of the cardiac action potential. hERG channels display unusually slow deactivation gating, which contributes to a resurgent current upon repolarization and may protect against po... | ['Animals', 'ERG1 Potassium Channel', 'Humans', 'Ion Channel Gating', 'Membrane Potentials', 'Protein Domains', 'Protons', 'Xenopus'] | 30,530,765 | [['B01.050'], ['D12.776.157.530.400.600.900.249.500', 'D12.776.543.550.450.750.900.249.500', 'D12.776.543.585.400.750.900.249.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.820.400', 'G04.835.400', 'G07.265.625'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['G02.111.570.820.709.275.750... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The relationship between hallux dorsiflexion and ankle joint complex frontal plane kinematics: a preliminary study. | BACKGROUND: It has been suggested that the function of the first metatarsophalangeal joint may be related to the motion of the ankle joint complex.OBJECTIVE: This study explored the relationship between ankle joint complex and first metatarsophalangeal joint motion during gait in a group of 14 who demonstrated clinical... | ['Adult', 'Ankle Joint', 'Braces', 'Female', 'Gait', 'Hallux Limitus', 'Humans', 'Male', 'Metatarsophalangeal Joint', 'Movement', 'Pilot Projects', 'Range of Motion, Articular', 'Statistics as Topic', 'Treatment Outcome'] | 15,836,940 | [['M01.060.116'], ['A02.835.583.378.062'], ['E07.858.442.743.319'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['C05.330.488.300', 'C05.550.445', 'C26.558.300.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.378.531'], ['G07.568', 'G11.427.410'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Determination of acrylamide monomer in polyacrylamide degradation studies by high-performance liquid chromatography. | A high-performance liquid chromatography method using C18 and ion-exchange columns in series is developed for the determination of acrylamide and acrylic acid monomers in polymeric samples. The C18 column acts as a guard column, trapping surfactants and impurities and retaining the nonionic species. The ion-exchange co... | ['Acrylamides', 'Acrylates', 'Chromatography, Gel', 'Chromatography, High Pressure Liquid', 'Glycine', 'Herbicides', 'Indicators and Reagents', 'Reproducibility of Results', 'Solutions', 'Spectrophotometry, Ultraviolet', 'Sunlight', 'Time Factors', 'Water Supply', 'Weather'] | 10,615,596 | [['D02.065.122', 'D02.241.081.069.094'], ['D02.241.081.069'], ['E05.196.181.400.250'], ['E05.196.181.400.300'], ['D12.125.481'], ['D27.720.031.700.366', 'D27.888.723.366'], ['D27.720.470.410'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['D26.776'], ['E05.196.712.726.802', 'E05.19... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Gene A product of phi X174 is required for site-specific endonucleolytic cleavage during single-stranded DNA synthesis in vivo. | A functional gene A product of phi X174 was found to be required at the stage of single-stranded DNA synthesis. A precursor complex that synthesizes single-stranded DNA (50S complex [Fujisawa and Hayashi, 1976]) was isolated from cells infected with wild-type or with temperature-sensitive gene A mutant phage. Proper cl... | ['Coliphages', 'DNA Replication', 'DNA, Single-Stranded', 'DNA, Viral', 'Endonucleases', 'Genes', 'Mutation', 'Temperature'] | 957,477 | [['B04.123.205'], ['G02.111.225', 'G05.226'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['D13.444.308.568'], ['D08.811.277.352.355'], ['G05.360.340.024.340'], ['G05.365.590'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Does intraspecific size variation in a predator affect its diet diversity and top-down control of prey? | It has long been known that intraspecific variation impacts evolutionary processes, but only recently have its potential ecological effects received much attention. Theoretical models predict that genetic or phenotypic variance within species can alter interspecific interactions, and experiments have shown that genotyp... | ['Animals', 'Biota', 'Body Size', 'Diet', 'Invertebrates', 'Predatory Behavior', 'Smegmamorpha', 'Species Specificity', 'Zooplankton'] | 21,687,670 | [['B01.050'], ['G16.500.275.157.049.100', 'N06.230.124.049.100'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['G07.203.650.240'], ['B01.050.500'], ['F01.145.113.111.600', 'F01.145.113.252.520'], ['B01.050.150.900.493.850'], ['G16.824'], ['B05.080.500.980']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Basal ganglia projections to zona incerta of dog diencephalon]. | Using the method of the retrograde axonal transport of horseradish peroxidase, it was determined that in dog, the projections from globus pallidus, nucleus entopeduncularis, substantia nigra and pedunculopontine nucleus were directed to all the regions of zona incerta. In the present study, no topical features were det... | ['Animals', 'Basal Ganglia', 'Diencephalon', 'Dogs', 'Horseradish Peroxidase', 'Neurons'] | 17,969,422 | [['B01.050'], ['A08.186.211.200.885.287.249'], ['A08.186.211.200.317'], ['B01.050.150.900.649.313.750.250.216.200'], ['D08.811.682.732.512'], ['A08.675', 'A11.671']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Value of discriminant analysis for screening of clonorchiasis sinensis]. | OBJECTIVE: To build a discriminant function of clonorchiasis sinensis using stepwise discriminant analysis, so as to investigate the feasibility of discriminant analysis for clonorchiasis sinensis screening.METHODS: Ten villages in Mulan County of Harbin City were sampled as the study sites using a cluster random sampl... | ['Animals', 'China', 'Cities', 'Clonorchiasis', 'Clonorchis sinensis', 'Discriminant Analysis', 'Feces', 'Female', 'Humans', 'Male', 'Mass Screening', 'Parasite Egg Count', 'Risk Factors'] | 32,458,613 | [['B01.050'], ['Z01.252.474.164'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['C01.610.335.865.148'], ['B01.050.500.500.736.715.520.210'], ['E05.318.740.350', 'N05.715.360.750.325', 'N06.850.520.830.350'], ['A12.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Experimental measurement of quality factor enhancement using slow light modes in one dimensional photonic crystal. | We experimentally investigate the effects of slow light modes within a one dimensional photonic crystal resonator. We show that the slow light mode leads to significant increase in the quality factor of the resonator. We provide a theoretical analysis explaining our experimental results. We also include the effect of d... | ['Computer Simulation', 'Computer-Aided Design', 'Crystallization', 'Equipment Design', 'Equipment Failure Analysis', 'Models, Theoretical', 'Photons', 'Quality Control', 'Refractometry'] | 18,542,662 | [['L01.224.160'], ['L01.224.108.150', 'L01.296.110.150'], ['E05.196.300', 'G02.171'], ['E05.320'], ['E05.325.192'], ['E05.599'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782'], ['J01.897.608'], ['E05.196.808', 'H01.671.617.755']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
A comparative randomized trial of intermittent intrahepatic arterial carboplatin- versus doxorubicin-lipiodol emulsion in advanced hepatocellular carcinoma (stage IV). | BACKGROUND/AIMS: The study was performed to investigate the anti-tumor effect, survival rate, and toxicity of intermittent intrahepatic infusion chemotherapy with carboplatin suspended in lipiodol.METHODOLOGY: We conducted a randomized controlled study containing either doxorubicin or carboplatin in 65 patients with ad... | ['Aged', 'Antibiotics, Antineoplastic', 'Antineoplastic Agents', 'Carboplatin', 'Carcinoma, Hepatocellular', 'Dose-Response Relationship, Drug', 'Doxorubicin', 'Drug Administration Schedule', 'Drug Combinations', 'Emulsions', 'Female', 'Humans', 'Infusions, Intra-Arterial', 'Iodized Oil', 'Liver Neoplasms', 'Male', 'Mi... | 15,239,261 | [['M01.060.116.100'], ['D27.505.954.248.106'], ['D27.505.954.248'], ['D02.257.125'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['E02.319.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A non-canonical phosphorylation site in â-casein A from non-Mediterranean water buffalo makes quantifiable the adulteration of Italian milk with foreign material by combined isoelectrofocusing-immunoblotting procedures. | The need of controlling illegal addition of water buffalo (WB) milk from foreign countries to the Italian counterpart devoted to the production of Protected Denomination of Origin (PDO) Mozzarella di Bufala Campana (MBC) cheese has promoted the development of simple, fast and cheap isoelectrofocusing (IEF) methods for ... | ['Animals', 'Binding Sites', 'Biomarkers', 'Buffaloes', 'Caseins', 'Food Quality', 'Fraud', 'Immunoblotting', 'Isoelectric Focusing', 'Milk', 'Phosphorylation'] | 30,502,135 | [['B01.050'], ['G02.111.570.120'], ['D23.101'], ['B01.050.150.900.649.313.500.380.135'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['J01.576.423.850.730', 'N06.850.601'], ['I01.198.240.300'], ['E05.478.566.320', 'E05.601.470.320'], ['E05.196.401.663', 'E05.301.300.663'], ['A12.200.455', 'A12.790', 'G07.203.100.70... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
Exploring how constraints created by other people influence intraindividual variation in objective performance measures. | Objective performance indicators have low test-retest reliability, particularly in complex jobs. Yet, little is actually known about the reasons why objective performance indicators lack temporal stability. The authors address this issue by using data from a sample of 106 professional football players to explore how th... | ['Adaptation, Psychological', 'Employee Performance Appraisal', 'Humans', 'Social Behavior', 'Social Environment', 'Workplace'] | 17,638,472 | [['F01.058'], ['N04.452.677.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.813'], ['I01.880.853.500'], ['N01.824.245.925', 'N04.452.677.975']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Lower urinary tract symptoms and risk of prostate cancer: the HUNT 2 Cohort, Norway. | Screening for early prostate cancer is frequently employed in the routine management of men with lower urinary tract symptoms (LUTS), but the evidence-base linking LUTS with prostate cancer is limited. We assessed the association of LUTS with a subsequent prostate cancer diagnosis in a prospective cohort study based on... | ['Adult', 'Cohort Studies', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Norway', 'Proportional Hazards Models', 'Prostatic Neoplasms', 'Severity of Illness Index', 'Urologic Diseases'] | 18,661,522 | [['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.116.630'], ['Z01.542.816.374'], ['E05.318.740.500.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Structural basis for the site-specific incorporation of lysine derivatives into proteins. | Posttranslational modifications (PTMs) of proteins determine their structure-function relationships, interaction partners, as well as their fate in the cell and are crucial for many cellular key processes. For instance chromatin structure and hence gene expression is epigenetically regulated by acetylation or methylati... | ['Amino Acyl-tRNA Synthetases', 'Archaeal Proteins', 'Catalytic Domain', 'Crystallography, X-Ray', 'Lysine', 'Methanosarcina', 'Models, Molecular', 'Molecular Sequence Data', 'Protein Processing, Post-Translational', 'Substrate Specificity'] | 24,760,130 | [['D08.811.464.263.200'], ['D12.776.090'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.196.309.742.225'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['B02.200.765.550.550'], ['E05.599.595'], ['L01.453.245.667'], ['G02.111.660.871.790.600', 'G02.111.691.600', 'G03.734.871.790.600', ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Non-target Effects of Naphthalene on the Soil Microbial Biomass and Bacterial Communities in the Subalpine Forests of Western China. | Naphthalene is a biocide of soil fauna, particularly of soil arthropods, that has been widely applied to test the functional roles of soil fauna in soil processes. However, whether the use of naphthalene to expel soil fauna has a non-target effect on soil bacteria in subalpine forests remains unclear. We conducted a na... | ['Bacteria', 'Biomass', 'China', 'Forests', 'High-Throughput Nucleotide Sequencing', 'Naphthalenes', 'Nitrogen', 'Phylogeny', 'Sequence Analysis, DNA', 'Soil', 'Soil Microbiology'] | 31,285,516 | [['B03'], ['G16.500.275.157.100', 'N06.230.124.100'], ['Z01.252.474.164'], ['G16.500.275.157.437', 'N06.230.124.343'], ['E05.393.760.319'], ['D02.455.426.559.847.638', 'D04.615.638'], ['D01.268.604', 'D01.362.625'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.760.700'], ['D20.721', 'G01.311.820', 'G16.500.275.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Investigation of solvent effects on UV-vis absorption spectra of dihydroxybenzene derivatives by solvatochromic parameters. | The solvatochromism of dihydroxybenzene derivatives as probes in 18 solvents were investigated in the UV-vis spectra. The position, intensity and shape of absorption bands change with various solvent nature. These changes were rationalized by solvatochromic parameters such as alpha, beta, ET(30), DN and AN using multip... | ['Benzene', 'Hydrogen', 'Hydroquinones', 'Molecular Structure', 'Resorcinols', 'Solvents', 'Spectrophotometry'] | 19,264,536 | [['D02.455.426.559.389.023'], ['D01.268.406', 'D01.362.340'], ['D02.455.426.559.389.657.393'], ['G02.111.570', 'G02.466'], ['D02.455.426.559.389.657.852'], ['D27.720.844'], ['E05.196.712.726', 'E05.196.867.826']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reduction of Bacterial Pathogens and Potential Surrogates on the Surface of Almonds Using High-Intensity 405-Nanometer Light. | The disinfecting properties of high-intensity monochromatic blue light (MBL) were investigated against Escherichia coli O157:H7, Salmonella , and nonpathogenic bacteria inoculated onto the surface of almonds. MBL was generated from an array of narrow-band 405-nm light-emitting diodes. Almonds were inoculated with highe... | ['Colony Count, Microbial', 'Escherichia coli O157', 'Food Handling', 'Food Microbiology', 'Prunus dulcis', 'Salmonella', 'Temperature'] | 28,221,904 | [['E01.370.225.875.220', 'E05.200.875.220'], ['B03.440.450.425.325.300.800.250.500', 'B03.660.250.150.180.100.800.250.500'], ['J01.576.423.200'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['B01.650.940.800.575.912.250.859.937.500... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Troglitazone administration limits infarct size by reduced phosphorylation of canine myocardial connexin43 proteins. | Troglitazone, an antidiabetic thiazolidinedione, has been shown to have a scavenging effect on reactive oxygen species, which can modulate expression of connexin43. The study purpose was to evaluate whether troglitazone provides cardioprotection and to assess whether the cardioprotection is associated with an attenuate... | ['Animals', 'Blood Glucose', 'Blotting, Western', 'Cardiotonic Agents', 'Chromans', 'Connexin 43', 'Dogs', 'Dose-Response Relationship, Drug', 'Free Radical Scavengers', 'Hemodynamics', 'Insulin', 'Male', 'Microscopy, Confocal', 'Myocardial Infarction', 'Myocardium', 'Phosphorylation', 'Superoxides', 'Thiazoles', 'Thia... | 12,969,882 | [['B01.050'], ['D09.947.875.359.448.500'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D27.505.954.411.222', 'D27.720.799.080'], ['D03.383.663.283.240', 'D03.633.100.150.240'], ['D12.776.543.585.250.200'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Picking and nibbling in children and adolescents with eating disorders. | OBJECTIVE: Picking and nibbling (P&N), defined as eating in an unplanned and repetitious way between meals and snacks, is prevalent among adults with eating disorders (EDs), but unexamined among youth with EDs. This study sought to assess the prevalence of P&N in youth with EDs and its association with ED and comorbid ... | ['Adolescent', 'Age Factors', 'Anorexia Nervosa', 'Anxiety Disorders', 'Binge-Eating Disorder', 'Body Weight', 'Bulimia Nervosa', 'Child', 'Comorbidity', 'Feeding Behavior', 'Female', 'Humans', 'Male', 'Meals', 'Prevalence'] | 26,282,064 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['F03.400.125'], ['F03.080'], ['F03.400.188'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['F03.400.250'], ['M01.060.406'], ['N05.715.350.225', 'N06.850.490.687'], ['F01.145.113.547', 'F01... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Human vagal baroreflex sensitivity fluctuates widely and rhythmically at very low frequencies. | Arterial pressure fluctuates rhythmically in healthy supine resting humans, who, from all outward appearances, are in a 'steady-state'. Others have asked, If baroreflex mechanisms are functioning normally, how can arterial pressure be so variable? We reanalysed data from nine healthy young adult men and women and teste... | ['Adrenergic beta-Agonists', 'Adult', 'Angiotensin-Converting Enzyme Inhibitors', 'Atenolol', 'Atropine', 'Baroreflex', 'Blood Pressure', 'Enalaprilat', 'Female', 'Humans', 'Male', 'Muscarinic Antagonists', 'Posture', 'Respiration', 'Supine Position'] | 16,002,447 | [['D27.505.519.625.050.100.200', 'D27.505.696.577.050.100.200'], ['M01.060.116'], ['D27.505.519.389.745.085'], ['D02.033.100.624.698.070', 'D02.033.755.624.698.070', 'D02.092.063.624.698.070'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An Australian survey of parent involvement in intervention for childhood speech sound disorders. | PURPOSE: To investigate how speech-language pathologists (SLPs) report involving parents in intervention for phonology-based speech sound disorders (SSDs), and to describe the home practice that they recommend. Further aims were to describe the training SLPs report providing to parents, to explore SLPs' beliefs and mot... | ['Adult', 'Australia', 'Child', 'Female', 'Health Knowledge, Attitudes, Practice', 'Health Personnel', 'Humans', 'Male', 'Parents', 'Speech Sound Disorder', 'Speech Therapy', 'Speech-Language Pathology', 'Surveys and Questionnaires'] | 28,816,080 | [['M01.060.116'], ['Z01.639.100', 'Z01.678.100.373'], ['M01.060.406'], ['F01.100.150.500', 'N05.300.150.410'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['F03.625.374.500'], ['E02.760.169.063.500.727.552', 'E02.831.727.552... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Executive function deficits in short-term abstinent cannabis users. | OBJECTIVES: Few cognitive tasks are adequately sensitive to show the small decrements in performance in abstinent chronic cannabis users. In this series of three experiments we set out to demonstrate a variety of tasks that are sufficiently sensitive to show differences in visual memory, verbal memory, everyday memory ... | ['Adolescent', 'Adult', 'Cognition', 'Female', 'Humans', 'Male', 'Marijuana Smoking', 'Memory', 'Mental Recall', 'Neuropsychological Tests', 'Smoking'] | 18,421,794 | [['M01.060.057'], ['M01.060.116'], ['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.610.875', 'F01.145.805.250.500'], ['F02.463.425.540'], ['F02.463.425.540.641'], ['F04.711.513'], ['F01.145.805']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Clinical characteristics of borderline ovarian tumors and stage I epithelial ovarian cancer: an analysis of 143 cases]. | OBJECTIVE: To study the clinical pathological characteristics and high risk factors for borderline ovarian tumor (BOT) and stage I epithelial ovarian cancer (EOC).METHODS: A total of 91 patients with BOT and 52 patients with stage IEOC who were diagnosed and treated in the Department of Gynecology, Peking University Pe... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Carcinoma, Endometrioid', 'Carcinoma, Ovarian Epithelial', 'Cystadenocarcinoma, Mucinous', 'Cystadenocarcinoma, Serous', 'Diagnosis, Differential', 'Female', 'Humans', 'Middle Aged', 'Neoplasm Staging', 'Neoplasms, Glandular and Epithelial', 'Ovarian Neoplasm... | 21,321,635 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['C04.557.470.200.025.240', 'C04.588.945.418.948.585.124', 'C13.351.500.056.630.705.331', 'C13.351.937.418.685.331', 'C13.351.937.418.875.200.124', 'C19.391.630.705.331'], ['C04.557.470.200.295', 'C04.588.322.455.199', 'C13.351.500.056.630... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Structure and expression of the Drosophila melanogaster gene for the U1 small nuclear ribonucleoprotein particle 70K protein. | A genomic clone encoding the Drosophila U1 small nuclear ribonucleoprotein particle 70K protein was isolated by hybridization with a human U1 small nuclear ribonucleoprotein particle 70K protein cDNA. Southern blot and in situ hybridizations showed that this U1 70K gene is unique in the Drosophila genome, residing at c... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Blotting, Northern', 'Blotting, Southern', 'Cloning, Molecular', 'DNA', 'Drosophila melanogaster', 'Gene Expression', 'Gene Library', 'Genes', 'Humans', 'Molecular Sequence Data', 'Molecular Weight', 'Oligonucleotide Probes', 'Poly A', 'RNA', 'RNA, Messenger', 'Ribon... | 1,692,955 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['E05.393.220'], ['D13.444.308'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A factor affecting stimulation of aminocylation in plants. | The presence of a factor stimulating the reaction of aminoacylation tRNAs was found in the seeds of lupin, with a molecular weight of 950 as estimated by gel filtration. The influence of this factor on the kinetics of the aminoacylation reactions of lupin, Escherichia coli, Baker's yeast and heterogeneous systems was i... | ['Amino Acids', 'Amino Acyl-tRNA Synthetases', 'Enzyme Activation', 'Escherichia coli', 'Isoleucine', 'Isoleucine-tRNA Ligase', 'Molecular Weight', 'Saccharomyces cerevisiae', 'Seeds', 'Transfer RNA Aminoacylation'] | 319,834 | [['D12.125'], ['D08.811.464.263.200'], ['G02.111.263', 'G03.328'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.125.070.577', 'D12.125.142.383'], ['D08.811.464.263.200.450'], ['G02.494'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['G02.11... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Enteric prevalence of adenovirus in human immunodeficiency virus seropositive patients. | To evaluate the prevalence of adenovirus strains in human immunodeficiency virus (HIV)-positive patients and to investigate their possible role in the onset of diarrhea, a total of 103 stools from HIV-seropositive patients at various stages of infection and 200 stools from sex and age cross-matched control subjects wer... | ['AIDS-Related Opportunistic Infections', 'Adenovirus Infections, Human', 'Adenoviruses, Human', 'Antigens, Viral', 'CD4 Lymphocyte Count', 'Diarrhea', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'HIV Infections', 'HIV Seronegativity', 'Humans', 'Male', 'Matched-Pair Analysis'] | 7,714,492 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['C01.925.256.076.045'], ['B04.280.030.500.350'], ['D23.050.327'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.1... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Epidemiologic studies among Amerindian populations of Amaz?nia. I. Pyoderma: prevalence and associated pathogens. | Pyoderma was studied among a representative sample of the residents of four remote Amerindian villages, Amazonas State, Brazil, during July-August 1976. The overall prevalence among the 775 inhabitants examined was 11%, with little intervillage variation. When the attack rates for the entire sample population were calc... | ['Adolescent', 'Adult', 'Brazil', 'Child', 'Child, Preschool', 'Corynebacterium diphtheriae', 'Female', 'Humans', 'Impetigo', 'Indians, South American', 'Infant', 'Male', 'Microbial Sensitivity Tests', 'Pyoderma', 'Serotyping', 'Skin', 'Staphylococcus aureus', 'Streptococcus pyogenes'] | 110,164 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Borderline tuberculoid leprosy--an unusual presentation: a case report. | A twenty-six year old lady presented herself with multiple erythmatous, scaly, well-defined, hypo-esthetic plaques over bilateral soles, face and left leg. Histopathology revealed features consistent with borderline tuberculoid leprosy. | ['Administration, Oral', 'Adult', 'Anti-Inflammatory Agents', 'Diagnosis, Differential', 'Female', 'Humans', 'Leprostatic Agents', 'Leprosy, Borderline', 'Prednisolone', 'Treatment Outcome'] | 19,295,116 | [['E02.319.267.100'], ['M01.060.116'], ['D27.505.954.158'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.954.122.085.777'], ['C01.150.252.410.040.552.475.371.850.249'], ['D04.210.500.745.432.769.795'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Suicidal adolescents--what should clinicians look for?]. | BACKGROUND: Over the past decades, suicidal behaviour has increased among adolescents. We wanted to explore what characterises adolescents who come in to see a general practitioner prior to a suicide attempt.MATERIAL AND METHOD: 87 % of a group of adolescents below the age of 20 (N = 92) who were admitted to hospital a... | ['Adolescent', 'Adolescent Behavior', 'Family Practice', 'Female', 'Humans', 'Male', 'Mental Disorders', 'Norway', 'Referral and Consultation', 'Risk Factors', 'Self Concept', 'Social Problems', 'Substance-Related Disorders', 'Suicide, Attempted', 'Surveys and Questionnaires'] | 14,508,544 | [['M01.060.057'], ['F01.145.022'], ['H02.403.340.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['Z01.542.816.374'], ['N04.452.758.849'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['F01.752.747.792'], ['I01.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Development of a liposome-based formulation for vitamin K1 nebulization on the skin. | Vitamin K1 (VK1) is a very lipophilic and photosensitive molecule contained in some vegetables. Recently, the use of VK1 on the skin has been proposed for different pharmaceutical or cosmeceutical applications. In this study, an innovative strategy for the administration of VK1 on the skin was proposed. In particular, ... | ['Aerosols', 'Animals', 'Drug Compounding', 'In Vitro Techniques', 'Liposomes', 'Nanocapsules', 'Nebulizers and Vaporizers', 'Skin Absorption', 'Swine', 'Vitamin K 1'] | 24,748,792 | [['D20.280.055', 'D26.255.165.055'], ['B01.050'], ['E05.916.270'], ['E05.481'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['D26.255.260.575', 'E02.319.300.380.575', 'J01.637.512.600.575'], ['E07.605'], ['G03.015.500.750', 'G03.787.024.500.750', 'G07.690.725.015.500.750', 'G13.750... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Purinergic signaling in the pulmonary neuroepithelial body microenvironment unraveled by live cell imaging. | Pulmonary neuroepithelial bodies (NEBs) are densely innervated groups of complex sensory airway receptors involved in the regulation of breathing. Together with their surrounding Clara-like cells, they exhibit stem cell potential through their capacity to regenerate depopulated areas of the epithelium following lung in... | ['Adenosine Triphosphate', 'Aniline Compounds', 'Animals', 'Calcium', 'Fluorescent Dyes', 'Immunohistochemistry', 'Kinetics', 'Lung', 'Mice', 'Mice, Inbred C57BL', 'Neuroepithelial Bodies', 'Pyridinium Compounds', 'Quinacrine', 'Receptors, Purinergic P2', 'Respiratory Mucosa', 'Signal Transduction', 'Suramin', 'Xanthen... | 19,050,048 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D02.092.146'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Plasma and skin concentration of 5-methoxypsoralen in psoriatic patients after oral administration. | The aim of this work was to investigate the distribution of 5-methoxypsoralen in the skin after oral administration of the drug and to examine the correlation between skin and plasma concentrations. 5-Methoxypsoralen skin concentration was measured in both healthy and psoriatic sites of 10 psoriatic patients after sing... | ['5-Methoxypsoralen', 'Administration, Oral', 'Adult', 'Dermis', 'Epidermis', 'Female', 'Humans', 'Male', 'Methoxsalen', 'Middle Aged', 'PUVA Therapy', 'Psoriasis', 'Tissue Distribution'] | 11,511,320 | [['D03.383.663.283.446.794.688', 'D03.633.100.150.446.794.688', 'D03.633.300.770.688'], ['E02.319.267.100'], ['M01.060.116'], ['A17.815.180'], ['A10.272.497', 'A17.815.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.663.283.446.794.500', 'D03.633.100.150.446.794.500', 'D03.633.300.770.500'], ['M01.060... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[THE ATOMIC-FORCE MICROSCOPY STUDY OF STRUCTURAL FUNCTIONAL CHARACTERISTICS OF NEUTROPHILS IN PATIENTS WITH CHRONIC OBSTRUCTIVE LUNG DISEASES IN PHASE OF EXACERBATION]. | The technique of atomic-force microscopy was applied to analyze the structural functional characteristics (morphology, force of adhesion, rigidity of membrane) of neutrophils in patients with chronic obstructive disease of lungs in phase of exacerbation. The regimen of force spectroscopy was applied to implement quanti... | ['Cell Membrane', 'Elastic Modulus', 'Female', 'Humans', 'Male', 'Microscopy, Atomic Force', 'Middle Aged', 'Neutrophils', 'Pulmonary Disease, Chronic Obstructive'] | 26,470,434 | [['A11.284.149'], ['G01.374.590.605'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['M01.060.116.630'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['C08.381.495.389']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of endoscopic sphincterotomy on gallbladder motility. | In experimental animals, sphincterotomy facilitates passage of solids from the gallbladder and inhibits gallstone formation apparently by improvement in gallbladder emptying. In humans, however, gallbladder emptying has not been studied following endoscopic sphincterotomy (ES) in patients with gallstones. We therefore ... | ['Adult', 'Case-Control Studies', 'Ceruletide', 'Cholelithiasis', 'Female', 'Gallbladder', 'Gallbladder Emptying', 'Gallstones', 'Gastrointestinal Agents', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Sphincterotomy, Endoscopic', 'Ultrasonography'] | 9,246,053 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D12.644.456.241'], ['C06.130.409'], ['A03.159.439'], ['G10.261.345'], ['C06.130.409.633', 'C06.130.564.332.500', 'C23.300.175.525'], ['D27.505.954.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Analysis of CC chemokine and chemokine receptor expression in solid ovarian tumours. | To understand the chemokine network in a tissue, both chemokine and chemokine receptor expression should be studied. Human epithelial ovarian tumours express a range of chemokines but little is known about the expression and localisation of chemokine receptors. With the aim of understanding chemokine action in this can... | ['Adenocarcinoma, Clear Cell', 'Base Sequence', 'Blotting, Northern', 'CD8-Positive T-Lymphocytes', 'Carcinoma', 'Carcinoma, Signet Ring Cell', 'Chemokines, CC', 'Cystadenocarcinoma, Serous', 'Endometrial Neoplasms', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Immunoenzyme Techniques', 'In Situ Hybri... | 11,556,842 | [['C04.557.470.200.025.045'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['C04.557.470.200'], ['C04.557.470.200.025.415', 'C04.557.470.590.415'], ['D1... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Physical activity in U.S. older adults with diabetes mellitus: prevalence and correlates of meeting physical activity recommendations. | OBJECTIVES: To compare the prevalence and correlates of meeting current recommendations for physical activity in older adults with and without diabetes mellitus (DM) in the United States.DESIGN: A cross-sectional, population-based sample.SETTING: The 2007 Behavioral Risk Factor Surveillance Survey, which employs random... | ['Aged', 'Case-Control Studies', 'Comorbidity', 'Cross-Sectional Studies', 'Diabetes Mellitus', 'Exercise', 'Female', 'Health Policy', 'Humans', 'Likelihood Functions', 'Logistic Models', 'Male', 'Multivariate Analysis', 'Patient Compliance', 'Socioeconomic Factors', 'United States'] | 21,226,683 | [['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.452.394.750', 'C19.246'], ['G11.427.410.698.277', 'I03.350'], ['I01.655.500.608.400', 'I01.880... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The use of physiological data to corroborate cospeciation events in symbiosis. | The symbiotic association between sepiolid squids (Family Sepiolidae) and luminous bacteria (Genus Vibrio) provides an unusually tractable model to study the evolution and speciation of mutualistic partnerships. Both host and symbiont can be cultured separately, providing a new avenue to test phylogenetic congruence th... | ['Animals', 'Decapodiformes', 'Phylogeny', 'Symbiosis', 'Vibrio'] | 11,924,500 | [['B01.050'], ['B01.050.500.644.116.150'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G06.550.800', 'G16.840'], ['B03.440.450.900.859', 'B03.660.250.830.830']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
In vivo confocal evaluation of the ocular surface morpho-functional unit in dry eye. | PURPOSE: To study, by a new, integrated, laser scanning confocal microscopy approach, the ocular surface morpho-functional unit in patients with primary Sjogren syndrome (SSI), non-Sjogren syndrome dry eye (non-SSDE), and meibomian gland disease (MGD).METHODS: Patients and age- and sex-matched control subjects (N = 60;... | ['Adult', 'Aged', 'Case-Control Studies', 'Cell Count', 'Conjunctiva', 'Dry Eye Syndromes', 'Epithelial Cells', 'Epithelium, Corneal', 'Eyelids', 'Female', 'Humans', 'Male', 'Microscopy, Confocal', 'Middle Aged', 'Prospective Studies', 'Young Adult'] | 23,670,123 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A09.371.060.200', 'A09.371.337.168'], ['C11.496.260'], ['A11.436'], ['A09.371.060.217.325', 'A10.272.510'], ['A01.456.505.420.504'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones. | Budding yeast Mec1, homolog of mammalian ATR, is an essential protein that mediates S-phase checkpoint responses and meiotic recombination. Elimination of Mec1 function leads to genomewide fork stalling followed by chromosome breakage. Breaks do not result from stochastic collapse of stalled forks or other incidental l... | ['Chromosome Breakage', 'Chromosomes, Fungal', 'DNA Replication', 'DNA, Fungal', 'Fungal Proteins', 'G1 Phase', 'G2 Phase', 'Genome, Fungal', 'Hydroxyurea', 'Interphase', 'Intracellular Signaling Peptides and Proteins', 'Mutation', 'Protein-Serine-Threonine Kinases', 'S Phase', 'Saccharomyces cerevisiae', 'Saccharomyce... | 12,142,538 | [['C23.550.210.170', 'G05.200.210.170', 'G05.365.590.175.175'], ['A11.284.187.360', 'A19.311', 'G05.360.162.360'], ['G02.111.225', 'G05.226'], ['D13.444.308.300'], ['D12.776.354'], ['G04.144.500.320'], ['G04.144.500.340'], ['G05.360.340.358.365'], ['D02.065.950.395'], ['G04.144.500'], ['D12.644.360', 'D12.776.476'], ['... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Residues and risk assessment of polycyclic aromatic hydrocarbons in the surface sediments and marine organisms from Dapeng Bay, Shenzhen]. | In order to assess contamination by polycyclic aromatic hydrocarbons (PAHs), surface sediments and marine organism samples of fish, shrimp and shellfish were collected from the Dapeng Bay, Shenzhen in October 2011. Concentrations fof sixteen priority PAHs were determined by gas chromatography and mass spectrometry (GC-... | ['Animals', 'Bays', 'Bivalvia', 'China', 'Ecosystem', 'Environmental Monitoring', 'Fishes', 'Gas Chromatography-Mass Spectrometry', 'Geologic Sediments', 'Polycyclic Aromatic Hydrocarbons', 'Risk Assessment', 'Shellfish', 'Water Pollutants, Chemical'] | 24,364,300 | [['B01.050'], ['G01.311.625.080'], ['B01.050.500.644.080'], ['Z01.252.474.164'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.493'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G01.311.330', 'G16.500.320'], ['D02.455.426.559.847', 'D04.615'], ['E05.318.740.600.800.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Identification of candidate genes downstream of TLR4 signaling after ozone exposure in mice: a role for heat-shock protein 70. | BACKGROUND: Toll-like receptor 4 (TLR4) is involved in ozone (O3)-induced pulmonary hyperpermeability and inflammation, although the downstream signaling events are unknown.OBJECTIVES: The aims of our study were to determine the mechanism through which TLR4 modulates O3-induced pulmonary responses and to use transcript... | ['Animals', 'Bronchoalveolar Lavage Fluid', 'Enzyme-Linked Immunosorbent Assay', 'HSP70 Heat-Shock Proteins', 'Male', 'Mice', 'Myeloid Differentiation Factor 88', 'Ozone', 'Pneumonia', 'Reverse Transcriptase Polymerase Chain Reaction', 'Signal Transduction', 'Toll-Like Receptor 4'] | 21,543,283 | [['B01.050'], ['E05.927.100.500'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D12.776.580.216.375'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.644.360.024.311', 'D12.776.157.057.074', 'D12.776.476.024.390'], ['D01.362.670.600'], ['C01.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aromatase expression in abdominal omental/visceral and subcutaneous fat depots: a comparison of pregnant and obese women. | OBJECTIVE: To investigate total and promoter expression of aromatase in subcutaneous and omental (visceral) fat and compare this expression in pregnant and obese women.DESIGN: Cross-sectional study.SETTING: Academic hospital.PATIENT(S): Six women undergoing elective cesarean section and three women undergoing bariatric... | ['Adult', 'Aromatase', 'Cross-Sectional Studies', 'Female', 'Gene Expression Regulation, Enzymologic', 'Humans', 'Intra-Abdominal Fat', 'Obesity', 'Omentum', 'Pregnancy', 'Pregnancy Proteins', 'Promoter Regions, Genetic', 'Subcutaneous Fat'] | 22,464,085 | [['M01.060.116'], ['D08.244.453.489.500', 'D08.244.453.915.099', 'D08.811.682.690.708.170.447.500', 'D08.811.682.690.708.170.915.099', 'D12.776.422.220.453.489.500', 'D12.776.422.220.453.915.099'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G05.308.320'], ['B01.050.150.900.649.313.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Health-related quality of life and patients' perceptions in interferon-treated multiple myeloma patients. Nordic Myeloma Study Group. | The effect of interferon on the health-related quality of life in multiple myeloma was assessed in two trials carried out by the Nordic Myeloma Study (Group (NMSG). In both trials, the EORTC QLQ-C30 questionnaire, supplemented with 11 items relating to interferon toxicity, was used. The first was a randomized controlle... | ['Adult', 'Antineoplastic Agents', 'Antineoplastic Combined Chemotherapy Protocols', 'Female', 'Health Status', 'Humans', 'Interferon-alpha', 'Male', 'Melphalan', 'Middle Aged', 'Multiple Myeloma', 'Patient Satisfaction', 'Prednisone', 'Quality of Life'] | 11,145,438 | [['M01.060.116'], ['D27.505.954.248'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890.250', 'D12.776.467.374.440.890.250', 'D23.529.374.440.890.250'], ['D02.455.526.728.650.594',... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Humanities [K]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Application of Instructional Design Principles in Developing an Online Information Literacy Curriculum. | An online information literacy curriculum was developed as an intervention to engage students in independent study and self-assessment of their learning needs and learning outcomes, develop proficiency in information skills, and foster lifelong learning. This column demonstrates how instructional design principles were... | ['Curriculum', 'Education, Medical, Undergraduate', 'Humans', 'Information Literacy', 'Internet', 'Program Development', 'Program Evaluation'] | 26,794,201 | [['I02.158'], ['I02.358.399.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.143.450'], ['L01.224.230.110.500'], ['N04.452.760'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Elevated ferric, calcium and magnesium ions in the brain induce protein aggregation in brain mitochondria. | OBJECTIVE: Alzheimer's disease and Parkinson's disease are two of several neurodegenerative disorders that affect the elderly. Although their aetiology remains uncertain, studies suggest that elevated aluminium or other metal ions in the brain directly influence the development of the histological abnormalities normall... | ['Aluminum Chloride', 'Aluminum Compounds', 'Animals', 'Brain', 'Calcium Chloride', 'Chlorides', 'Electrophoresis, Polyacrylamide Gel', 'Ferric Compounds', 'Magnesium Chloride', 'Mitochondrial Proteins', 'Rabbits'] | 23,155,955 | [['D01.056.031', 'D01.210.450.150.025'], ['D01.056'], ['B01.050'], ['A08.186.211'], ['D01.146.300', 'D01.210.450.150.150'], ['D01.210.450.150', 'D01.248.497.158.215'], ['E05.196.401.402', 'E05.301.300.319'], ['D01.490.100'], ['D01.210.450.150.500', 'D01.524.475'], ['D12.776.575'], ['B01.050.150.900.649.313.968.700']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metabolic effects of acute hyperketonaemia in man before and during an hyperinsulinaemic euglycaemic clamp. | 1. The effects of acutely raising blood ketone body levels to those seen after 72 h of starvation were examined in 10 subjects after an overnight fast. Metabolic rate and respiratory exchange ratio were measured with indirect calorimetry before and during an insulin-glucose clamp. Arteriovenous differences were measure... | ['3-Hydroxybutyric Acid', 'Acute Disease', 'Adipose Tissue', 'Adult', 'Basal Metabolism', 'Blood Glucose', 'Fatty Acids, Nonesterified', 'Female', 'Forearm', 'Glucose Clamp Technique', 'Glycerol', 'Humans', 'Hydroxybutyrates', 'Insulin', 'Ketone Bodies', 'Lipolysis', 'Male', 'Respiratory Transport', 'Starvation'] | 8,062,504 | [['D02.241.081.114.937.349', 'D02.241.511.429.349', 'D02.522.585.087', 'D10.251.400.143.781.500'], ['C23.550.291.125'], ['A10.165.114'], ['M01.060.116'], ['G03.295.154'], ['D09.947.875.359.448.500'], ['D10.251.310'], ['A01.378.800.585'], ['E01.370.225.124.100.350', 'E05.196.500', 'E05.200.124.100.350'], ['D02.033.800.8... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
In vitro mechanical testing of glass fiber-reinforced composite used as dental implants. | AIM: The aim of this study was to evaluate the design of fiber-reinforced composite (FRC) on some mechanical properties of a dental implant.METHODS AND MATERIALS: FRC implants were fabricated using different polymerization conditions and designs of the glass-fiber structure. Specimens were tested with a cantilever bend... | ['Analysis of Variance', 'Composite Resins', 'Dental Implants', 'Dental Prosthesis Design', 'Dental Stress Analysis', 'Elasticity', 'Glass', 'Materials Testing', 'Phase Transition', 'Pliability', 'Shear Strength', 'Torsion, Mechanical'] | 18,264,524 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E06.780.346.625', 'E06.912.145'], ['E06.308'], ['G0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The morphology of the foetal sigmoid colon in the African population: a possible predisposition to sigmoid volvulus. | AIM: This study aimed to determine the morphological types of the foetal sigmoid colon and establish if the anatomical predisposition to sigmoid volvulus is present in Black African foetuses. Sigmoid volvulus affects Black Africans in our province more frequently than other ethnic groups, and males more than females. I... | ['African Continental Ancestry Group', 'Colon, Sigmoid', 'Female', 'Fetal Organ Maturity', 'Fetus', 'Humans', 'Intestinal Volvulus', 'Male', 'Organ Size', 'Sex Factors'] | 26,112,767 | [['M01.686.508.100'], ['A03.556.124.526.356.668', 'A03.556.249.249.356.668'], ['G07.345.500.325.235.750', 'G07.345.500.325.377.249', 'G08.686.784.170.157.750'], ['A16.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531.568', 'C23.300.970.500'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.1... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Long-term prophylaxis with norfloxacin versus nitrofurantoin in women with recurrent urinary tract infection. | A total of 102 women with recurrent urinary tract infections were included in this open randomized study; 55 received 200 mg of norfloxacin daily and 47 received 50 mg of nitrofurantoin daily over 6 months. Fifty-three and 41 women from the norfloxacin- and nitrofurantoin-treated groups, respectively, completed the 6-m... | ['Female', 'Humans', 'Middle Aged', 'Nitrofurantoin', 'Norfloxacin', 'Recurrence', 'Urinary Tract Infections'] | 1,929,272 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.640.600.566', 'D03.383.312.649.566'], ['D03.633.100.810.835.322.374'], ['C23.550.291.937'], ['C01.915', 'C12.777.892', 'C13.351.968.892']] | ['Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Nitric oxide inhibits enterocyte mitochondrial phospholipase D. | Mitochondrial damage is one of the prominent features of cell death in oxidative stress and related pathological conditions. Alteration in membrane lipid composition may be responsible for the mitochondrial damage. In this study, we have shown that intestinal mitochondria contain an active phospholipase D (PLD) which i... | ['Calcium', 'Enzyme Activation', 'Enzyme Inhibitors', 'Glutathione', 'Hemoglobins', 'Intestines', 'Membrane Lipids', 'Mitochondria', 'Nitric Oxide', 'Nitroprusside', 'Nitroso Compounds', 'Oxidants', 'Oxidative Stress', 'Phosphatidic Acids', 'Phosphatidylethanolamines', 'Phospholipase D', 'Polyamines', 'S-Nitrosoglutath... | 9,280,295 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.263', 'G03.328'], ['D27.505.519.389'], ['D12.644.456.448'], ['D12.776.124.400', 'D12.776.422.316.762'], ['A03.556.124'], ['D10.570'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Osteocalcin is vitamin D-dependent during the perinatal period in the rat. | The vitamin D-dependence of renal calbindin D-28K and osteocalcin during the perinatal period was studied in fetuses (days 18 and 21) and neonates (days 2, 12, 17 and 22) of rats fed either a standard diet (0.85% Ca-0.7% P; "high Ca-P diet" rats) or a mildly Ca-P restricted diet (0.2% Ca-0.2% P; "low Ca-P diet" rats). ... | ['Animals', 'Animals, Newborn', 'Calbindins', 'Calcium', 'Diet', 'Ergocalciferols', 'Female', 'Femur', 'Kidney', 'Osteocalcin', 'Perinatology', 'Phosphates', 'Pregnancy', 'Rats', 'Rats, Inbred Strains', 'S100 Calcium Binding Protein G'] | 2,101,404 | [['B01.050'], ['B01.050.050.282'], ['D12.776.157.125.090'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G07.203.650.240'], ['D04.210.500.247.222.474', 'D04.210.500.247.808.412', 'D04.210.500.812.768.462', 'D10.570.938.439'], ['A02.835.232.043.150'], ['A05.810.453'], ['D12.776.157.125.700'], ['H02.403.670.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Incidence of transfusion reactions: a multicenter study utilizing systematic active surveillance and expert adjudication. | BACKGROUND: Prevalence estimates of the serious hazards of transfusion vary widely. We hypothesized that the current reporting infrastructure in the United States fails to capture many transfusion reactions and undertook a multicenter study using active surveillance, data review, and adjudication to test this hypothesi... | ['Blood Safety', 'Humans', 'Incidence', 'Retrospective Studies', 'Risk Management', 'Tertiary Care Centers', 'Transfusion Medicine', 'Transfusion Reaction'] | 27,460,200 | [['E02.792.833.230.500', 'E05.760.833.230.500', 'N06.850.780.200.450.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Pattern of clefts of the lip and palate managed over a three year period at a Nairobi hospital in Kenya. | BACKGROUND: The pattern of cleft lip and palate in the African population remains uncertain. The few studies of clefts in African populations have suggested that the pattern of these defects may be significantly different from those reported in other population groups. However, most of these studies have been based on ... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Cleft Lip', 'Cleft Palate', 'Family', 'Female', 'Hospitals, Community', 'Humans', 'Infant', 'Infant, Newborn', 'Kenya', 'Male', 'Middle Aged'] | 16,619,710 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['C07.465.409.225', 'C07.465.525.164', 'C07.650.525.164', 'C16.131.850.525.164'], ['C05.500.460.185', 'C05.660.207.540.460.185', 'C07.320.440.185', 'C07.465.525.185', 'C07.650.500.460.185', 'C07.650.525.185', 'C16.131.621.207.540.460.185', 'C16.13... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A population-based cohort study on the use of hormone treatment and endometrial cancer in southern Sweden. | Our aim was to determine the risk of endometrial cancer associated with long-term use of combined hormone therapy (HT) and low-potency estrogens. In this prospective population-based cohort, 40,000 women aged 25-64 years, without prior cancer or hysterectomy, were included. The women answered 2 questionnaires at a 10-y... | ['Adult', 'Cohort Studies', 'Endometrial Neoplasms', 'Estrogens', 'Female', 'Humans', 'Middle Aged', 'Registries', 'Sweden'] | 19,326,453 | [['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['D27.505.696.399.472.277'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.970', 'N04.452.859.819', 'N... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Placebo Effects in Clinical Trials Evaluating Patients with Uncontrolled Persistent Asthma. | Rationale: Patients with uncontrolled, persistent asthma can show substantial health improvements when administered placebo.Objectives: We analyzed five randomized, placebo-controlled clinical trials that assessed subjects with uncontrolled, persistent asthma to determine the magnitudes of placebo effects across differ... | ['Adult', 'Aged', 'Anti-Asthmatic Agents', 'Asthma', 'Disease Progression', 'Female', 'Forced Expiratory Volume', 'Humans', 'Male', 'Middle Aged', 'Placebo Effect', 'Quality of Life', 'Randomized Controlled Trials as Topic', 'Severity of Illness Index'] | 31,063,408 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.796.050'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C23.550.291.656'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N05.715.350.350.625', 'N06.850.490.734.87... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Nephrin is necessary for podocyte recovery following injury in an adult mature glomerulus. | Nephrin (Nphs1) is an adhesion protein that is expressed at the podocyte intercellular junction in the glomerulus. Nphs1 mutations in humans or deletion in animal genetic models results in a developmental failure of foot process formation. A number of studies have shown decrease in expression of nephrin in various prot... | ['Animals', 'Cell Membrane', 'Gene Deletion', 'Kidney Glomerulus', 'Membrane Proteins', 'Mice', 'Podocytes', 'Protein Stability', 'Proteinuria'] | 29,924,795 | [['B01.050'], ['A11.284.149'], ['G05.365.590.762.320', 'G05.558.800.320'], ['A05.810.453.324.359', 'A05.810.453.736.520'], ['D12.776.543'], ['B01.050.150.900.649.313.992.635.505.500'], ['A05.810.453.324.359.372.650', 'A05.810.453.736.520.720', 'A11.436.720'], ['G02.111.700'], ['C12.777.934.734', 'C13.351.968.934.734', ... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Medical education in Thailand. | In order to make training more relevant to community needs, medical educators throughout Thailand have been attempting to address issues concerning the training of their undergraduates. Support for a reorientation of medical education and acceptance of the frame-work put forward by the World Health Organization are evi... | ['Community Medicine', 'Curriculum', 'Education, Medical, Undergraduate', 'Health Planning', 'Health Policy', 'Primary Health Care', 'Thailand'] | 1,614,353 | [['H02.403.220'], ['I02.158'], ['I02.358.399.450'], ['N03.349', 'N03.706.615.302'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['N04.590.233.727'], ['Z01.252.145.841']] | ['Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Genetic diversity and structure of Neotyphodium species and their host Achnatherum sibiricum in a natural grass-endophyte system. | Achnatherum sibiricum (Poaceae) is a perennial bunchgrass native to the Inner Mongolia Steppe of China. This grass is commonly infected by epichlo? endophytes with high-infection frequencies. Previously, we identified two predominant Neotyphodium spp., N. sibiricum and N. gansuense. In the present study, genetic divers... | ['China', 'DNA, Fungal', 'Ecosystem', 'Gene Flow', 'Genetic Variation', 'Genetics, Population', 'Microsatellite Repeats', 'Neotyphodium', 'Poaceae', 'Sequence Analysis, DNA', 'Symbiosis'] | 20,352,205 | [['Z01.252.474.164'], ['D13.444.308.300'], ['G16.500.275.157', 'N06.230.124'], ['G05.330.159'], ['G05.365'], ['H01.158.273.343.335'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500'], ['B01.300.107.501.775', 'B01.300.381.570'], ['B01.650.940.800.575.912.250.822'], ['E05.393.760.700'... | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Combined use of BDNF, ascorbic acid, low oxygen, and prolonged differentiation time generates tyrosine hydroxylase-expressing neurons after long-term in vitro expansion of human fetal midbrain precursor cells. | Freshly isolated fetal midbrain neural precursor cells (NPCs) that maintain the potential to differentiate into dopamine (DA) neurons represent a valuable source for cell therapy in Parkinson's disease. However, it is poorly understood why midbrain NPCs lose their dopaminergic differentiation potential after long-term ... | ['Ascorbic Acid', 'Brain-Derived Neurotrophic Factor', 'Cell Culture Techniques', 'Cell Differentiation', 'Cells, Cultured', 'Fetus', 'Gene Expression Regulation, Enzymologic', 'Humans', 'Mesencephalon', 'Neurons', 'Oxygen', 'Stem Cells', 'Time', 'Time Factors', 'Tyrosine 3-Monooxygenase'] | 18,652,826 | [['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.152'], ['A11.251'], ['A16.378'], ['G05.308.320'], ['B01.050.150.900.649.313.988.40... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
20 versus 30 mg omeprazole once daily: effect on healing rates in 115 duodenal ulcer patients. | In a double-blind, dose comparison multicenter trial 115 patients with duodenal ulcer were treated with either 20 or 30 mg oral omeprazole once daily for 4 weeks. There was no difference in the healing rates for the two groups after 2 and 4 weeks. After 2 weeks with 20 and 30 mg healing frequencies were 79.0 and 72.7%,... | ['Adult', 'Benzimidazoles', 'Clinical Trials as Topic', 'Duodenal Ulcer', 'Female', 'Humans', 'Male', 'Middle Aged', 'Omeprazole', 'Time Factors', 'Wound Healing'] | 3,512,351 | [['M01.060.116'], ['D03.633.100.103'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.886.640.074.500', 'D03.383.725.024.500', 'D03.633.100.103.034.500'], ['G01... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of robotic and laparoscopic ultrasound probes for robotic partial nephrectomy. | OBJECTIVES: To evaluate and compare perioperative outcomes of robotic partial nephrectomy (RPN) using robotic and laparoscopic ultrasound probe for tumor identification.MATERIALS AND METHODS: Data from 75 consecutive RPN procedures using a laparoscopic ultrasound probe (January 2009- November 2010) and 75 consecutive R... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Kidney Neoplasms', 'Laparoscopes', 'Laparoscopy', 'Male', 'Middle Aged', 'Nephrectomy', 'Retrospective Studies', 'Robotics', 'Surgery, Computer-Assisted', 'Ultrasonography, Interventional'] | 23,510,382 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['E07.230.220.520', 'E07.858.240.520'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 |
[Prenatal diagnosis and management of a case of cardiac tumor]. | The cardiac tumors are very rare when diagnosed in the prenatal period. The authors report a typical case diagnosed in the 27 week of gestation by echocardiography. This is the first case reported in Panama. | ['Adult', 'Electrocardiography', 'Female', 'Heart Neoplasms', 'Heart Ventricles', 'Humans', 'Infant, Newborn', 'Pregnancy', 'Rhabdomyoma', 'Ultrasonography, Prenatal'] | 1,924,905 | [['M01.060.116'], ['E01.370.370.380.240', 'E01.370.405.240'], ['C04.588.894.309', 'C14.280.459'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G08.686.784.769'], ['C04.557.450.590.540.700'], ['E01.370.350.850.865', 'E01.370.378.630.865']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Gangliosides synchronize the rhythm of protein synthesis in hepatocytes in vitro]. | The kinetics of protein synthesis was studied in the cultures of rat hepatocytes on slides covered with collagen or fibronectin and kept in a serum-free medium 199 complemented by albumin and insulin. No protein synthesis rhythm was found in the cultures with markedly separated cells obtained from a diluted suspension ... | ['Animals', 'Cells, Cultured', 'Culture Media, Conditioned', 'Culture Media, Serum-Free', 'Gangliosides', 'Liver', 'Periodicity', 'Protein Biosynthesis', 'Proteins', 'Rats', 'Time Factors', 'Tritium'] | 9,004,894 | [['B01.050'], ['A11.251'], ['D27.720.470.305.250', 'E07.206.250'], ['D27.720.470.305.255', 'E07.206.255'], ['D09.400.410.420.025.475', 'D10.390.470.025.475', 'D10.570.877.360.025.475'], ['A03.620'], ['G01.910.645', 'G07.180.562'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['D12.776'], ['B01.050.150.900.649.313... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The bark-eating habits in primates, with special references to their status in the diet of wild chimpanzees. | Chimpanzees of the Mahali Mountains, Tanzania, were recorded to chew barks of 21 species of trees and wood vines. They mainly utilize the barks of savanna-living deciduous trees during the mid-rainy season of the year when few fruits are available. The degree of their dependence on bark for food varies drastically year... | ['Animals', 'Feeding Behavior', 'Haplorhini', 'Pan troglodytes', 'Plants, Edible', 'Seasons', 'Tanzania'] | 819,337 | [['B01.050'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400'], ['B01.050.150.900.649.313.988.400.112.400.620'], ['B01.650.510'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['Z01.058.290.120.840']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Intrigue: Phase III study of ripretinib versus sunitinib in advanced gastrointestinal stromal tumor after imatinib. | Ripretinib (DCC-2618) is a novel, type II tyrosine switch control inhibitor designed to broadly inhibit activating and drug-resistant mutations in KIT and PDGFRA. Ripretinib has emerged as a promising investigational agent for the treatment of gastrointestinal stromal tumor owing to targeted inhibition of secondary res... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Drug Resistance, Neoplasm', 'Female', 'Follow-Up Studies', 'Gastrointestinal Neoplasms', 'Gastrointestinal Stromal Tumors', 'Humans', 'Imatinib Mesylate', 'Male', 'Middle Aged', 'Mutation', 'Naphthyridines', 'Prognos... | 31,755,321 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['G07.690.773.984.395'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['C04.557.450... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Trends of body composition among adolescents according to maturation stage and body mass index. | BACKGROUND: Excessive increases in percentage body fat (%BF) according to sex may pose greater risks of chronic diseases.OBJECTIVE: To evaluate trends of body composition according to sexual maturation stage and body mass index (BMI) of adolescents.METHOD: Data about weight, height, lean mass, fat mass, %BF, BMI and se... | ['Adolescent', 'Body Composition', 'Body Height', 'Body Mass Index', 'Brazil', 'Child', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Obesity', 'Overweight'] | 23,585,176 | [['M01.060.057'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['Z01.107.757.176'], ['M01.060.406'], ['E05.318.372.500.875', '... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Replaced common hepatic artery originating from the superior mesenteric artery and prepancreatic, anterior course in a patient with cephalic pancreaticoduodenectomy - case report. | The presence of hepatic arterial variations is particularly important for patients undergoing cephalic pancreaticoduodenectomy, because it can lead to unnecessary incidents or postoperative complications. We present the case of a patient with pancreatic head neoplasm in which the cephalic pancreaticoduodenectomy was pe... | ['Hepatic Artery', 'Humans', 'Male', 'Mesenteric Artery, Superior', 'Middle Aged', 'Pancreaticoduodenectomy'] | 28,730,242 | [['A07.015.114.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.565.755'], ['M01.060.116.630'], ['E04.210.760']] | ['Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Development of a feeding trochophore in the polychaete Hydroides elegans. | Hydroides elegans is an indirectly developing polychaete with equal spiral cleavage, gastrulation by invagination, and a feeding trochophore. Expression of several transcription factors and differentiation genes has been characterized. Comparative analysis reveals evolutionarily conserved roles. For example, the synexp... | ['Animals', 'Biological Evolution', 'Cell Differentiation', 'Gastrulation', 'Gene Expression Regulation, Developmental', 'Larva', 'Polychaeta', 'Transcription Factors'] | 25,690,971 | [['B01.050'], ['G05.045', 'G16.075'], ['G04.152'], ['G07.345.500.325.180.812'], ['G05.308.310'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B01.050.500.091.700'], ['D12.776.930']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predictors of length of hospital stay in elderly hip fracture patients. | The purpose of this study was to assess the relationship between prefracture characteristics and length of stay (LOS) at the authors' institution. Three hundred eighty-nine consecutive elderly hip fracture patients' preoperative characteristics, comorbidities, fracture type, and surgical and hospital course were retros... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Cerebrovascular Disorders', 'Comorbidity', 'Female', 'Hip Fractures', 'Humans', 'Length of Stay', 'Male', 'Regression Analysis', 'Renal Insufficiency, Chronic', 'Retrospective Studies', 'Risk Factors', 'Treatment Outcome'] | 23,628,571 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300', 'C14.907.253'], ['N05.715.350.225', 'N06.850.490.687'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['E05.318... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Single-strand conformation polymorphism analysis using capillary electrophoresis. | Single-strand conformation polymorphism (SSCP) is one of the most frequently used mutation detection methods. This unit describes a method of SSCP with automated analysis by capillary electrophoresis in order to increase the capacity and throughput. A protocol is provided for sample preparation. For a medium throughput... | ['Base Sequence', 'DNA Primers', 'Electrophoresis, Capillary', 'Mutation', 'Polymorphism, Single-Stranded Conformational'] | 18,428,343 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['E05.196.401.190', 'E05.301.300.190'], ['G05.365.590'], ['G05.365.795.600']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Superior vena cava rupture during balloon angioplasty and stent placement to relieve superior vena cava syndrome: a case report. | Percutaneous stenting of the superior vena cava (SVC) has been an accepted therapy for SVC syndrome for more than a decade. Complications are uncommon and usually of minor consequence. Three previous reports have described ruptures of the SVC during venoplasty with death on one occasion. We report a fourth case of SVC ... | ['Adult', 'Angioplasty, Balloon', 'Blood Vessel Prosthesis', 'Female', 'Heart Injuries', 'Humans', 'Stents', 'Superior Vena Cava Syndrome', 'Vena Cava, Superior'] | 17,311,770 | [['M01.060.116'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['E07.695.110'], ['C26.891.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.750'], ['C14.907.800'], ['A07.015.908.949.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Complement activation in Lyme neuroborreliosis--increased levels of C1q and C3a in cerebrospinal fluid indicate complement activation in the CNS. | A strong initial inflammatory response is important in neuroborreliosis. Since complement is a main player in early inflammation, we monitored the concentration and activation of complement in plasma and cerebrospinal fluid from 298 patients, of whom 23 were diagnosed with neuroborreliosis. Using sandwich ELISAs, we fo... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Central Nervous System', 'Child', 'Child, Preschool', 'Complement Activation', 'Complement C1q', 'Complement C3', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Lyme Neuroborreliosis', 'Male', 'Middle Aged', 'Statistics, Nonparametric'] | 17,157,926 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A08.186'], ['M01.060.406'], ['M01.060.406.448'], ['G12.274'], ['D12.776.124.486.274.050.270'], ['D12.776.124.050.140', 'D12.776.124.486.274.250'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Short- and long-term mortality after an acute illness for elderly whites and blacks. | OBJECTIVE: To estimate racial differences in mortality at 30 days and up to 2 years following a hospital admission for the elderly with common medical conditions.DATA SOURCES: The Medicare Provider Analysis and Review File and the VA Patient Treatment File from 1998 to 2002 were used to extract patients 65 or older adm... | ['African Americans', 'Aged', 'Aged, 80 and over', 'European Continental Ancestry Group', 'Female', 'Gastrointestinal Hemorrhage', 'Heart Failure', 'Hip Fractures', 'Hospital Mortality', 'Humans', 'Male', 'Medicare', 'Myocardial Infarction', 'Pneumonia', 'Retrospective Studies', 'Stroke', 'Survival Analysis', 'Survivor... | 18,355,259 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.686.508.400'], ['C06.405.227', 'C23.550.414.788'], ['C14.280.434'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.9... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Genetic abnormalities in sporadic parathyroid adenomas: loss of heterozygosity for chromosome 3q markers flanking the calcium receptor locus. | Inactivating mutations of the parathyroid cell calcium receptor (CaR) gene cause one form of familial benign/hypocalciuric hypercalcemia, and in homozygous form, cause neonatal severe primary hyperparathyroidism with parathyroid hyperplasia. Thus, we postulated that partial or total loss of CaR function might contribut... | ['Adenoma', 'Alleles', 'Calcium-Binding Proteins', 'Chromosome Mapping', 'Chromosomes, Human, Pair 3', 'DNA', 'Genetic Markers', 'Heterozygote', 'Humans', 'Parathyroid Neoplasms'] | 7,593,455 | [['C04.557.470.035'], ['G05.360.340.024.340.030'], ['D12.776.157.125'], ['E05.393.183'], ['A11.284.187.520.300.235.250', 'G05.360.162.520.300.235.250'], ['D13.444.308'], ['D23.101.387', 'G05.695.450'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.322.525', 'C04.588.443.680', 'C19.344.525'... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The deamination of noradrenaline and 5-hydroxytryptamine by rat brain and heart monoamine oxidase and their inhibition by cimoxatone, toloxatone and MD 770222. | In both rat brain and heart, noradrenaline and 5-hydroxytryptamine are metabolised predominantly by monoamine oxidase-A. The Km values for 14C-noradrenaline in the rat brain and heart are 290 microM and 300 microM, respectively, whereas for 14C-5-hydroxytryptamine the values are 180 microM and 140 microM, respectively.... | ['Animals', 'Brain', 'Deamination', 'In Vitro Techniques', 'Kinetics', 'Male', 'Mitochondria', 'Monoamine Oxidase', 'Monoamine Oxidase Inhibitors', 'Myocardium', 'Nerve Tissue Proteins', 'Norepinephrine', 'Oxazoles', 'Oxazolidinones', 'Rats', 'Rats, Inbred Strains', 'Serotonin'] | 6,633,672 | [['B01.050'], ['A08.186.211'], ['G02.111.192', 'G02.607.157', 'G03.222'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D08.811.682.664.750'], ['D27.505.519.389.616'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D12.776.631'], ['D02.033.100.291.502', 'D02.09... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of early versus delayed timing of left ventricular assist device implantation as a bridge-to-transplantation: An analysis of the UNOS dataset. | BACKGROUND: Placement of left ventricular assist devices (LVAD) as a bridge-to-heart transplantation (HTx) has rapidly expanded due to organ donor shortage. However, the timing of LVAD implantation is variable and it remains unclear if earlier implantation improves survival.METHODS: We analyzed 14,187 adult candidates ... | ['Adult', 'Disease-Free Survival', 'Female', 'Follow-Up Studies', 'Germany', 'Heart Failure', 'Heart Transplantation', 'Heart-Assist Devices', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Retrospective Studies', 'Survival Rate', 'Time Factors', 'United States', 'Waiting Lists'] | 26,618,255 | [['M01.060.116'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['Z01.542.315'], ['C14.280.434'], ['E04.100.376.475', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Tac expression induced by Epstein-Barr virus is restricted on non-transformable B lymphocytes. | During the course of a comparative study dealing with the immortalization of lymphocytes from a large number of normal healthy donors, we found that B cells of two of these individuals could not be immortalized by Epstein-Barr virus (EBV) under the standard conditions. The expression of the Tac antigen on the membrane ... | ['B-Lymphocytes', 'Cell Transformation, Viral', 'Cells, Cultured', 'Gene Expression Regulation', 'Herpesvirus 4, Human', 'Humans', 'Interleukin-2', 'Lymphocyte Activation', 'Pokeweed Mitogens', 'Receptors, Immunologic', 'Receptors, Interleukin-2'] | 2,837,437 | [['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['C04.697.098.500.160', 'C23.550.727.098.500.160', 'G06.920.143'], ['A11.251'], ['G05.308'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['B01.050.150.900.649.... | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structure of the lc and nmpC outer membrane porin protein genes of lambdoid bacteriophage. | The lc gene of the lambdoid bacteriophage PA-2 and the nmpC gene located on a defective lambdoid prophage in the 12-min region of the Escherichia coli K12 chromosome have been sequenced. The porin proteins encoded by these two genes were almost identical, with only 4 of the 365 residues of the precursor forms of the pr... | ['Amino Acid Sequence', 'Bacterial Outer Membrane Proteins', 'Bacteriophage lambda', 'Base Sequence', 'DNA Restriction Enzymes', 'DNA, Bacterial', 'DNA, Viral', 'Escherichia coli', 'Gene Expression Regulation', 'Plasmids', 'Porins'] | 3,017,988 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097.120', 'D12.776.543.100'], ['B04.123.150.800.230', 'B04.123.205.230', 'B04.280.090.800.230'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D13.444.308.212'], ['D13... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Differential predictors of strain and gain among husbands caring for wives with dementia. | Given that women predominate in the caregiving role, researchers have largely focused on the experience of female caregivers. This cross-sectional study takes a beginning step toward understanding the differential predictors of negative (i.e., strain) and positive (i.e., gain) appraisals among 74 husbands caring for wi... | ['Adaptation, Psychological', 'Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Caregivers', 'Cross-Sectional Studies', 'Female', 'Forecasting', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Regression Analysis', 'Spouses', 'Wisconsin'] | 9,127,980 | [['F01.058'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The role of HCA2 (GPR109A) in regulating macrophage function. | We investigated the novel role of HCA2 (GPR109A) and its ligand nicotinic acid in regulating macrophage function. Hca2 expression in the RAW264.7 murine macrophage cell line is strongly induced by LPS treatment and correlates with the expression of TNF-á. Treatment with 300 ìM nicotinic acid (reported EC50 3 ìM, peak p... | ['Animals', 'Biological Transport, Active', 'Cell Line, Tumor', 'Chemotaxis', 'Interleukins', 'Lipopolysaccharides', 'Lipoproteins, LDL', 'Macrophage Activation', 'Macrophages', 'Mice', 'NF-kappa B', 'Niacin', 'Receptors, G-Protein-Coupled', 'Receptors, Nicotinic', 'Tumor Necrosis Factor-alpha'] | 23,882,124 | [['B01.050'], ['G03.143.310'], ['A11.251.210.190', 'A11.251.860.180'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['D12.644.276.374.465', 'D12.776.467.374.465', 'D23.529.374.465'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.52... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Osteogenesis from cultured chick periostea has a specific requirement for chloride. | Bone development, like embryonic development in general, depends on a particular internal electrical milieu. Ions are the carriers of currents that maintain this internal environment. In embryonic bone, chloride is a major carrier of such current. To explore the role chloride plays in embryonic bone development we perf... | ['Acid Phosphatase', 'Alkaline Phosphatase', 'Animals', 'Cell Survival', 'Cells, Cultured', 'Chick Embryo', 'Chlorides', 'Culture Media', 'Culture Techniques', 'Dose-Response Relationship, Drug', 'Osteogenesis', 'Periosteum', 'Time Factors'] | 10,934,662 | [['D08.811.277.352.650.025'], ['D08.811.277.352.650.035'], ['B01.050'], ['G04.346'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['D01.210.450.150', 'D01.248.497.158.215'], ['D27.720.470.305', 'E07.206'], ['E05.481.500'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A neurobehavioral model of 2,5-hexanedione-induced neuropathy. | Although hexacarbons have been extensively studied as models of dying-back axonal degeneration, there has been little neurobehavioral investigation of these compounds. We have exposed Sprague-Dawley rats to 0.5% 2,5-hexanedione (2,5-HD), and followed neurobehavioral deficits continuously in the same animals throughout ... | ['Animals', 'Axons', 'Behavior, Animal', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Exploratory Behavior', 'Female', 'Hexanones', 'Ketones', 'Motor Activity', 'Motor Skills', 'Nerve Degeneration', 'Nervous System', 'Rats', 'Rats, Inbred Strains', 'Reflex'] | 7,177,309 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['F01.145.113'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G07.690.936.500'], ['F01.145.387', 'F01.658.370'], ['D02.522.520'], ['D02.522'], ['F01.145.632', 'G11.427.410.698'], ['F02.808.260'], ['C23.550.737... | ['Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
First Turkish experiences of assisted beating-heart coronary artery bypass graft with the Impella Microaxial Ventricular Assist Device. | The importance of minimally invasive cardiac operations, performed off-pump, without the support of cardiopulmonary bypass (CPB), is continuously increasing. Complete revascularization of obstructed coronary arteries is needed to obtain a better long-term outcome. Insertion into the left ventricle of an efficient micro... | ['Aged', 'Blood Vessel Prosthesis', 'Coronary Artery Bypass, Off-Pump', 'Heart-Assist Devices', 'Humans', 'Male', 'Middle Aged', 'Miniaturization', 'Pilot Projects', 'Prosthesis Design', 'Treatment Outcome', 'Turkey'] | 20,150,044 | [['M01.060.116.100'], ['E07.695.110'], ['E04.100.376.719.332.199', 'E04.100.814.868.750.199', 'E04.928.220.520.220.189'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['J01.897.520'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Using smartphone apps in STD interviews to find sexual partners. | OBJECTIVES: Smartphone applications (apps) are increasingly used to facilitate casual sexual relationships, increasing the risk of sexually transmitted diseases (STDs). In STD investigations, traditional contact elicitation methods can be enhanced with smartphone technology during field interviews.METHODS: In 2013, the... | ['Adolescent', 'Adult', 'Contact Tracing', 'Continental Population Groups', 'Homosexuality, Male', 'Humans', 'Internet', 'Male', 'Mobile Applications', 'Sexual Partners', 'Sexually Transmitted Diseases', 'Young Adult'] | 25,931,628 | [['M01.060.057'], ['M01.060.116'], ['E05.318.270', 'N06.850.520.270', 'N06.850.780.200.225'], ['M01.686.508'], ['F01.145.802.975.500.600', 'G08.686.867.500.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['L01.224.900.685'], ['M01.778'], ['C01.221.812', 'C01.778', 'C12.294.668', 'C13.35... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Identification of new tumor suppressor genes based on in vivo functional inactivation of a candidate gene. | As a step towards developing a new functional test for the identification of tumor suppressor genes, human wild type and mutant RB genes were expressed in the mouse A9 fibrosarcoma cell line under the transcriptional regulation of the tetracycline repressor using two new vectors: pLNCtTA and pETI. Following passage of ... | ['Animals', 'Fibrosarcoma', 'Gene Expression Regulation, Neoplastic', 'Genes, Retinoblastoma', 'Genes, Tumor Suppressor', 'Genetic Vectors', 'Humans', 'Mice', 'Mice, SCID', 'Neoplasm Transplantation', 'Tumor Cells, Cultured'] | 10,371,207 | [['B01.050'], ['C04.557.450.565.590.350', 'C04.557.450.795.350'], ['G05.308.370'], ['G05.360.340.024.340.375.249.400', 'G05.360.340.024.340.415.400.400'], ['G05.360.340.024.340.375.249', 'G05.360.340.024.340.415.400'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.5... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitative measurement of protease ligand conformation. | The tendency for protease ligands to bind in an extended conformation has been suggested as an important factor for the identification of compounds of medicinal importance. Here we present a novel graph-theoretical method giving a quantitative measure of ligand conformation, and through application of this method to a ... | ['Ligands', 'Models, Molecular', 'Molecular Conformation', 'Peptide Hydrolases'] | 18,204,905 | [['D27.720.470.480'], ['E05.599.595'], ['G02.111.570.820'], ['D08.811.277.656']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gerontological research aiming at practical work and planning. | This is an attempt at an overview of research findings related to practical outcomes as well as of the main problems of the elderly, of the institutions providing services, of the staff working in the field, as far as they are highlighted by research findings. It seems necessary to at least analyse in short conditions ... | ['Aged', 'Aging', 'Community Health Services', 'Geriatrics', 'Germany, West', 'Health Services for the Aged', 'Humans', 'Middle Aged', 'Rehabilitation, Vocational', 'Research Design', 'Social Adjustment'] | 7,257,512 | [['M01.060.116.100'], ['G07.345.124'], ['N02.421.143'], ['H02.403.355'], ['Z01.586.350'], ['N02.421.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.760.169.063.500.782', 'E02.831.782', 'N02.421.784.644'], ['E05.581.500', 'H01.770.644.728'], ['F01.145.813.621']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Low-level lead exposure alters morphine antinociception in neonatal rats. | Administration of lead (at 300 and 1000 ppm) in the maternal drinking water from conception to weaning impaired the antinociceptive activity of morphine in 10-day-old neonatal rats. Blood lead levels in these animals were below 50 microgram/100 ml in the high lead dose group and below 35 microgram/100 ml in the low lea... | ['Analgesia', 'Animals', 'Female', 'Lead', 'Lead Poisoning', 'Male', 'Morphine', 'Pregnancy', 'Rats', 'Rats, Inbred Strains', 'Spectrophotometry, Atomic', 'Time Factors'] | 6,474,503 | [['E03.091'], ['B01.050'], ['D01.268.556.435', 'D01.552.544.435'], ['C25.723.522.750'], ['D03.132.577.249.562.571', 'D03.605.497.607.587', 'D03.633.400.686.607.587', 'D04.615.723.795.576.571'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical significance of anti-multiple nuclear dots/Sp100 autoantibodies. | BACKGROUND: Autoantibodies against discrete variable-sized dots observed in HEp2 cells by indirect immunofluorescence (IIF) test, called multiple nuclear dots (MND), have been closely associated with primary biliary cirrhosis (PBC). Some authors have argued that this antibody is also present in connective tissue diseas... | ['Antigens, Nuclear', 'Autoantibodies', 'Autoantigens', 'Enzyme-Linked Immunosorbent Assay', 'Fluorescent Antibody Technique, Indirect', 'Humans', 'Liver Cirrhosis, Biliary', 'Lupus Erythematosus, Systemic', 'Nuclear Proteins'] | 14,531,539 | [['D12.776.660.625', 'D23.050.290'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D23.050.422'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.5... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coconut oil cake--a potential raw material for the production of alpha-amylase. | Solid-state fermentation (SSF) was carried out using coconut oil cake (COC) as substrate for the production of alpha-amylase using a fungal culture of Aspergillus oryzae. Raw COC supported the growth of the culture, resulting in the production of 1372 U/gds alpha-amylase in 24 h. Process optimization using a single par... | ['Aspergillus oryzae', 'Biomass', 'Bioreactors', 'Coconut Oil', 'Fermentation', 'Glucose', 'Kinetics', 'Maltose', 'Plant Oils', 'Starch', 'Temperature', 'Time Factors', 'alpha-Amylases'] | 15,051,078 | [['B01.300.381.081.500'], ['G16.500.275.157.100', 'N06.230.124.100'], ['E07.115', 'J01.897.120.115'], ['D10.627.700.186'], ['G02.111.158.249', 'G03.191.249'], ['D09.947.875.359.448'], ['G01.374.661', 'G02.111.490'], ['D09.698.365.450', 'D09.698.629.305.523', 'D09.947.750.523'], ['D10.627.700', 'D20.215.784.750'], ['D05... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Reverse second and third dorsal metacarpal artery fasciocutaneous flaps for repair of distal- and middle-segment finger soft tissue defects. | The present study evaluated the clinical efficacy of reverse second and third dorsal metacarpal artery fasciocutaneous flaps for repair of distal- and middle-segment finger soft tissue defects. A total of 14 patients with distal- and middle-segment finger soft tissue defects complicated by exposure of the phalanx or te... | ['Adult', 'Aged', 'Fascia', 'Female', 'Finger Injuries', 'Fingers', 'Humans', 'Male', 'Middle Aged', 'Reconstructive Surgical Procedures', 'Skin Transplantation', 'Soft Tissue Injuries', 'Surgical Flaps'] | 21,780,013 | [['M01.060.116'], ['M01.060.116.100'], ['A02.340', 'A10.165.425'], ['C26.448.429'], ['A01.378.800.667.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.680'], ['E02.095.147.725.700', 'E04.680.275.850', 'E04.936.580.700'], ['C26.808'], ['A10.850.710', 'E07.862.710']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Systemic natural killer activity following cardiac engraftment in the rat: lack of correlation with graft survival. | The systemic NK activity was studied both in untreated rats which acutely reject allogeneic heterotopic heart grafts and in cyclosporine-treated rats which tolerate their transplants. The trend and magnitude of changes in NK activity were similar at all time points for the two animal groups. Compared to naive rats, pea... | ['Animals', 'Cyclosporins', 'Cytotoxicity, Immunologic', 'Graft Survival', 'Heart Transplantation', 'Immunity, Innate', 'Killer Cells, Natural', 'Lymph Nodes', 'Male', 'Rats', 'Rats, Inbred Strains', 'Spleen', 'Thymus Gland', 'Time Factors'] | 3,527,444 | [['B01.050'], ['D04.345.566.235', 'D12.644.641.235'], ['G12.287'], ['G12.875.545.340'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['G12.450.564'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['A10.549.400', 'A15.382.520.604.412'], ['B01.050.150.900.649.313.992... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preparation of ethyl magnesium bromide for regiospecific analysis of triacylglycerols. | This paper presents a procedure for preparation of a Grignard reagent, ethyl magnesium bromide, used for partial deacylation of triacylglycerols (TAG) in their regiospecific analysis. Magnesium turnings were reacted with ethereal solution of bromoethane in a screw-capped test tube to synthesize 2 mL of 1 M ethyl magnes... | ['Acylation', 'Fatty Acids', 'Hydrocarbons, Brominated', 'Isomerism', 'Models, Chemical', 'Organometallic Compounds', 'Solutions', 'Temperature', 'Triglycerides'] | 18,622,130 | [['G02.111.012', 'G02.607.063', 'G03.040'], ['D10.251'], ['D02.455.526.368'], ['G02.111.570.685', 'G02.607.445'], ['E05.599.495'], ['D02.691'], ['D26.776'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['D10.351.801']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Involvement of PtdIns(4,5)P2 in the regulatory mechanism of small intestinal P-glycoprotein expression. | Previously, we reported that repeated oral administration of etoposide (ETP) activates the ezrin/radixin/moesin (ERM) scaffold proteins for P-glycoprotein (P-gp) via Ras homolog gene family member A (RhoA)/Rho-associated coiled-coil containing protein kinase (ROCK) signaling, leading to increased ileal P-gp expression.... | ['1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine', 'ATP Binding Cassette Transporter, Subfamily B', 'Animals', 'Blotting, Western', 'Cytoskeletal Proteins', 'Enzyme Inhibitors', 'Etoposide', 'Fluorobenzenes', 'Gene Expression Regulation', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Ileum', 'Immunoprecipitation', ... | 24,311,454 | [['D02.886.590.700.545', 'D03.383.606.527', 'D03.633.100.531.400'], ['D12.776.157.530.100.075', 'D12.776.157.530.450.074.500.500.250', 'D12.776.395.550.020.400', 'D12.776.543.550.192.400', 'D12.776.543.585.100.200', 'D12.776.543.585.450.074.500.500.250'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of prey density on predators: conspicuousness and attack success are sensitive to spatial scale. | In contrast to the numerous studies that have examined the response of predators to prey group size, little is known about how prey density affects prey detection and the accuracy of attacks. We demonstrate that increasing the density of Daphnia magna swarms increases conspicuousness to a natural predator, the three-sp... | ['Animals', 'Daphnia', 'Food Chain', 'Population Density', 'Predatory Behavior', 'Smegmamorpha', 'Spatial Behavior'] | 19,231,967 | [['B01.050'], ['B01.050.500.131.365.150.200'], ['G16.500.275.157.250', 'N06.230.124.250'], ['N01.224.600', 'N06.850.505.400.600'], ['F01.145.113.111.600', 'F01.145.113.252.520'], ['B01.050.150.900.493.850'], ['F01.145.875']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cecal colonization of chicks by bovine-derived strains of Campylobacter. | Campylobacter jejuni and Campylobacter coli strains were isolated from feces of dairy cattle at farms with no known problem due to campylobacteria. Farms were located in the northeast, desert southwest, and Pacific west. Twenty isolates were identified by ribotyping with a RiboPrinter. The ability of these bovine isola... | ['Animals', 'Campylobacter Infections', 'Campylobacter fetus', 'Cattle', 'Cecum', 'Chickens', 'DNA, Bacterial', 'DNA, Ribosomal', 'Helicobacter pylori', 'Species Specificity'] | 14,708,992 | [['B01.050'], ['C01.150.252.400.177'], ['B03.440.180.325', 'B03.660.150.235.250.500.220'], ['B01.050.150.900.649.313.500.380.271'], ['A03.556.124.526.209', 'A03.556.249.249.209'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D13.444.308.212'], ['D13.444.308.475'], ['B03.440.500.550', 'B03.660.150.2... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interocular comparison of nerve fiber layer thickness and its relation with optic disc size in normal subjects. | We conducted an investigation of the relation between RNFL thickness and optic disc size along with an interocular comparison of optic disc size, RNFL thickness, and RNFL density in healthy subjects. A total of 64 normal eyes from 32 Korean volunteers were enrolled in this study. A GDx Nerve Fiber Analyzer with softwar... | ['Adult', 'Female', 'Humans', 'Lasers', 'Male', 'Nerve Fibers', 'Optic Disk', 'Optic Nerve', 'Visual Field Tests', 'Weights and Measures'] | 12,162,521 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.490', 'E07.710.520'], ['A08.675.542', 'A11.671.501'], ['A08.800.800.120.680.660', 'A09.371.729.690'], ['A08.800.800.120.680'], ['E01.370.380.850.962'], ['E05.978']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dopamine-dependent neurodegeneration in Drosophila models of familial and sporadic Parkinson's disease. | Parkinson's disease has been found to be caused by both, genetic and environmental factors. Despite the diversity of causes involved, a convergent pathogenic mechanism might underlie the special vulnerability of dopaminergic neurons in different forms of Parkinsonism. In recent years, a number of reports have proposed ... | ['Animals', 'Animals, Genetically Modified', 'Disease Models, Animal', 'Dopamine', 'Drosophila melanogaster', 'Humans', 'Models, Genetic', 'Nerve Degeneration', 'Parkinson Disease', 'Rotenone'] | 20,211,259 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.397'], ['C23.550.737'], ... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Megalin mediates selenoprotein P uptake by kidney proximal tubule epithelial cells. | Selenoprotein P (Sepp1) contains most of the selenium in blood plasma, and it is utilized by the kidney, brain, and testis as a selenium source for selenoprotein synthesis. We recently demonstrated that apolipoprotein E receptor-2 (ApoER2) is required for Sepp1 uptake by the testis and that deletion of ApoER2 reduces t... | ['Animals', 'Binding Sites', 'Epithelial Cells', 'Gene Expression Regulation', 'Kidney Tubules', 'LDL-Receptor Related Proteins', 'Low Density Lipoprotein Receptor-Related Protein-2', 'Male', 'Mice', 'Mice, Transgenic', 'Models, Biological', 'Protein Structure, Tertiary', 'Receptors, Lipoprotein', 'Selenoprotein P', 'T... | 18,174,160 | [['B01.050'], ['G02.111.570.120'], ['A11.436'], ['G05.308'], ['A05.810.453.736.560'], ['D12.776.526', 'D12.776.543.750.710.450.500'], ['D12.776.526.200', 'D12.776.543.750.710.450.500.200', 'D23.050.422.500.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lipid peroxidation in rat AH-130 hepatoma cells enriched in vitro with arachidonic acid. | Tumor cells generally display low lipid peroxidation. A low content of polyunsaturated fatty acids in membrane phospholipids is a possible cause of their decreased susceptibility to lipid peroxidation. To investigate the importance of substrate availability in eliciting lipid peroxidation and to study cell viability in... | ['Animals', 'Arachidonic Acids', 'Ascorbic Acid', 'Cell Survival', 'Culture Media', 'Ferrous Compounds', 'Lipid Peroxidation', 'Liver Neoplasms, Experimental', 'Male', 'Membrane Lipids', 'Microsomes, Liver', 'Rats'] | 1,873,805 | [['B01.050'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['G04.346'], ['D27.720.470.305', 'E07.206'], ['D01.490.200'], ['G02.111.515', 'G03.295.531.587'], ['C04.588.274.623.460', 'C04.619.540', 'C06.301.623.460', 'C06.552.697.580', 'E05.598.500.496.750... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of norepinephrine contractions by diltiazem on aorta and pulmonary artery from young and aged rats: influence of alpha-adrenoceptor reserve. | Inhibition of contractile responses to norepinephrine by either diltiazem (1 microM) or by reducing the extracellular calcium (from 2.5-0.25 mM) has been examined on isolated ring preparations of aorta and pulmonary artery from young (2 months old) and aged (19-21 months old) rats. On aorta, the reduction in the norepi... | ['Age Factors', 'Animals', 'Aorta', 'Diltiazem', 'Male', 'Norepinephrine', 'Pulmonary Artery', 'Rats', 'Receptors, Adrenergic, alpha', 'Vasoconstriction'] | 2,838,598 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['A07.015.114.056'], ['D03.633.100.079.150'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830', 'D02.455.426.559.389.657.166.175.830'], ['A07.015.114.715'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.543.750.670.300.300... | ['Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
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