Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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The second international standard for chlortetracycline. | As supplies of the International Standard for Chlortetracycline were practically exhausted, it was replaced. The potency of the second international standard was defined on the basis of an international collaborative assay comprising 157 individual assays performed in 9 laboratories in 6 countries. The mean potencies o... | ['Australia', 'Chlortetracycline', 'Europe', 'International Cooperation', 'Laboratories', 'United States', 'World Health Organization'] | 4,540,683 | [['Z01.639.100', 'Z01.678.100.373'], ['D02.455.426.559.847.562.900.146', 'D04.615.562.900.146'], ['Z01.542'], ['I01.615.500'], ['J03.520', 'N02.278.487'], ['Z01.107.567.875'], ['N03.540.514.718.800']] | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
The Interactive Effects of Personal Resources on Teachers' Work Engagement and Withdrawal Intentions: A Structural Equation Modeling Approach. | This research contributes to the current knowledge on teacher well-being by examining an integrated model with a personal resource (i.e., emotional intelligence) explaining teacher withdrawal intention through a mediator (i.e., work engagement) and considering the moderator effect of a second personal resource (i.e., t... | ['Cross-Sectional Studies', 'Emotional Intelligence', 'Female', 'Humans', 'Intention', 'Latent Class Analysis', 'Male', 'Mental Healing', 'School Teachers', 'Work Engagement'] | 32,218,113 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.752.543.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.650', 'F02.463.306'], ['E05.318.740.250.338', 'G17.035.625', 'L01.224.050.687', 'N05.715.360.750.200.375', 'N06.850.520.830.250.338'], ['E02.190.525.500', 'E02.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Mourning, insight, and reduction of suicide risk in schizophrenia. | Literature on the assessment of suicide risk in individuals with schizophrenia is summarized, including the risk factors shared in common with the general population, illness-specific risk factors, and times of heightened risk in the course of the illness. Because depression emerges as a significant risk factor, it is ... | ['Denial, Psychological', 'Depression', 'Diagnosis, Differential', 'Grief', 'Humans', 'Risk Factors', 'Schizophrenia', 'Social Perception', 'Suicide, Attempted'] | 15,342,330 | [['F01.393.200'], ['F01.145.126.350'], ['E01.171'], ['F01.470.142.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['F03.700.750'], ['F02.463.593.752'], ['F01.145.126.980.875.6... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
The relation of cortisol levels with hippocampus volumes under baseline and challenge conditions. | Several studies using animal models have revealed an inverse relation between gluco-corticoid levels and hippocampus volumes. This inverse relation has been interpreted as reflecting the role of the hippocampus in modulating glucocorticoid secretion, as well as the effect of glucocorticoids on the hippocampus. The obje... | ['Adolescent', 'Adult', 'Data Interpretation, Statistical', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Functional Laterality', 'Hippocampus', 'Humans', 'Hydrocortisone', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Saliva'] | 17,936,736 | [['M01.060.057'], ['M01.060.116'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['F02.830.297.425', 'G11.561.225.425'], ['A08.186.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Optimized glucuronide hydrolysis for the detection of psilocin in human urine samples. | In order to develop a sensitive and reliable analytical method for psilocin (PC) in urine samples, the hydrolysis conditions including the acid, alkaline and enzymatic hydrolyses have been investigated by monitoring not only PC but also psilocin glucuronide (PCG) by liquid chromatography tandem mass spectrometry (LC-MS... | ['Adolescent', 'Chromatography, High Pressure Liquid', 'Female', 'Glucuronides', 'Hallucinogens', 'Humans', 'Hydrolysis', 'Mass Spectrometry', 'Psilocybin', 'Sensitivity and Specificity'] | 14,581,081 | [['M01.060.057'], ['E05.196.181.400.300'], ['D02.241.081.844.915.162.500', 'D02.241.152.811.162.750', 'D02.241.511.902.915.162.750', 'D09.811.922.162.750'], ['D27.505.696.388', 'D27.505.954.427.700.372'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.380'], ['E05.196.566'], ['D03.132.436.613', 'D03.633.100.473... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Thomas Hodgkin and his disease]. | Thomas Hodgkin (1798-1866), born into a family of Quakers, would remain faithful all his life to the principles and rules of the 'Society of Friends'. He studied pharmacy and medicine in London, Edinburgh and Paris. As curator for the museum of pathological anatomy of Guy's Hospital (1825-1837) he introduced modern, or... | ['England', 'History, 18th Century', 'History, 19th Century', 'Hodgkin Disease', 'Humans'] | 22,495,009 | [['Z01.542.363.300'], ['K01.400.504.875'], ['K01.400.504.937'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Geographicals [Z]', 'Humanities [K]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Serum fucosylated haptoglobin in chronic liver diseases as a potential biomarker of hepatocellular carcinoma development. | BACKGROUND: Fucosylation is one of the most important glycosylation events involved in cancer and inflammation. We previously developed a lectin antibody ELISA kit to measure fucosylated haptoglobin (Fuc-Hpt), which we identified as a novel cancer biomarker. In this study, we investigated Fuc-Hpt as a biomarker in chro... | ['Biomarkers, Tumor', 'Carcinoma, Hepatocellular', 'Disease Progression', 'Early Detection of Cancer', 'Fucose', 'Haptoglobins', 'Humans', 'Liver Neoplasms'] | 25,060,348 | [['D23.101.140'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['C23.550.291.656'], ['E01.390.500'], ['D09.254.488'], ['D12.776.124.050.300', 'D12.776.124.790.106.394', 'D12.776.377.715.085.394', 'D12.776.395.560.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modeling and simulation of point-non-point source effluent trading in Taihu Lake area: perspective of non-point sources control in China. | The past decades have witnessed some efforts in point source water pollution controls in China. However, adequate abatement efforts have not been implemented on non-point source control, and non-point source contributions remain and have increased as a share of surface water degradation. It has been noted that conventi... | ['Agriculture', 'Cost-Benefit Analysis', 'Decision Making', 'Environment', 'Models, Theoretical', 'Risk Assessment', 'Water Movements', 'Water Pollution'] | 15,144,776 | [['J01.040'], ['N03.219.151.125'], ['F02.463.785.373'], ['G16.500.275', 'N06.230'], ['E05.599'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['G16.500.971', 'N06.230.132.644.750', 'N06.230.850'], ['N06.850.460.790']] | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Effect of high-dose methylprednisolone therapy on phagocyte function in systemic lupus erythematosus. | Circulating phagocytes play a major role in the defence of the host against microbial infection. In an attempt to identify the reason for the unusual susceptibility to infection of patients with systemic lupus erythematosus (SLE) various parameters of phagocytic cell function were assessed kinetically in whole blood, a... | ['Adult', 'Cell Count', 'Cell Movement', 'Female', 'Humans', 'Lactoferrin', 'Lupus Erythematosus, Systemic', 'Methylprednisolone', 'Methylprednisolone Hemisuccinate', 'Middle Aged', 'Neutrophils', 'Phagocytes', 'Phagocytosis', 'Staphylococcus aureus', 'Streptococcus pneumoniae', 'Time Factors'] | 6,383,232 | [['M01.060.116'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.198', 'G07.568.500.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.760.471', 'D08.811.277.656.959.350.471', 'D12.776.157.427.750.249', 'D12.776.256.159.750.816.500.507', 'D12.776.377.457.507', 'D1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Atloido-axoid erosive osteoarthritis. Apropos of 3 cases]. | Three cases of unilateral atloido-axis arthropathy are described in women aged 39 to 69 years. The initial diagnosis of arthritis made in view of the severity of the clinical (severe pain and stiffness) and radiological (marked chondrolysis, subchondral erosions), manifestations was contested in the absence of any labo... | ['Adult', 'Aged', 'Arthritis', 'Axis, Cervical Vertebra', 'Cervical Atlas', 'Diagnosis, Differential', 'Female', 'Humans', 'Osteoarthritis', 'Radiography', 'Synostosis'] | 7,100,805 | [['M01.060.116'], ['M01.060.116.100'], ['C05.550.114'], ['A02.835.232.834.151.383'], ['A02.835.232.834.151.500'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.114.606', 'C05.799.613'], ['E01.370.350.700'], ['C05.116.099.370.894', 'C05.660.906', 'C16.131.621.906']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Equilibrium binding of amphotericin B and its methyl ester and borate complex to sterols. | Scatchard analysis of the binding of amphotericin B to sterols in egg phosphatidylcholine/sterol vesicles revealed that amphotericin B was bound to ergosterol by approximately one order of magnitude more tightly than to cholesterol. Amphotericin B methyl ester formed a tighter complex with each of the sterols investiga... | ['Amphotericin B', 'Borates', 'Kinetics', 'Liposomes', 'Phosphatidylcholines', 'Sterols', 'Structure-Activity Relationship'] | 7,059,605 | [['D02.540.576.500.500'], ['D01.132.250.075', 'D01.248.497.158.076', 'D02.203.130.075'], ['G01.374.661', 'G02.111.490'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['D10.570.755.375.760.400.800'], ['D04.210.500.247.808', 'D10.570.938'], ['G02.111.830', 'G07.690.773.997']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Bicyclic substituted hydroxyphenylmethanones as novel inhibitors of 17â-hydroxysteroid dehydrogenase type 1 (17â-HSD1) for the treatment of estrogen-dependent diseases. | Estradiol (E2), the most important estrogen in humans, is involved in the initiation and progression of estrogen-dependent diseases such as breast cancer and endometriosis. Its local production in the target cell is regulated by 17â-hydroxysteroid dehydrogenase type 1 (17â-HSD1), which catalyzes E2-formation by reducti... | ['Cell Line, Tumor', 'Drug Design', 'Drug Stability', 'Estradiol Dehydrogenases', 'Estrogen Receptor alpha', 'Estrogen Receptor beta', 'Female', 'Humans', 'In Vitro Techniques', 'Microsomes, Liver', 'Phenols', 'Placenta', 'Pregnancy', 'Structure-Activity Relationship', 'Thiazoles', 'Thiophenes'] | 20,977,238 | [['A11.251.210.190', 'A11.251.860.180'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['E05.916.330'], ['D08.811.682.047.436.375.280'], ['D12.776.826.750.350.174'], ['D12.776.826.750.350.262'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A11.284.835.540.541'], ['D02.455.426.559... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Postfailure modulus strongly affects microcracking and mechanical property change in human iliac cancellous bone: a study using a 2D nonlinear finite element method. | A two-dimensional (2D) finite element (FE) method was used to estimate the ability of bone tissue to sustain damage as a function of postfailure modulus. Briefly, 2D nonlinear compact-tension FE models were created from quantitative back-scattered electron images taken of human iliac crest bone specimens. The effects o... | ['Compressive Strength', 'Computer Simulation', 'Elastic Modulus', 'Finite Element Analysis', 'Fractures, Bone', 'Humans', 'Ilium', 'Models, Biological', 'Nonlinear Dynamics', 'Stress, Mechanical', 'Tensile Strength'] | 18,672,244 | [['G01.374.180'], ['L01.224.160'], ['G01.374.590.605'], ['E05.355'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043.825.434'], ['E05.599.395'], ['E05.599.850', 'H01.548.675'], ['G01.374.835'], ['G01.374.850']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Fate in the soil of an oil additive of plant origin. | The methyl ester of oleic acid, a plant oil derivative, can be used as an additive oil for pesticides. We compared the biodegradability in soil of this oil with that of a mineral oil by means of laboratory experiments using lysimeters of 70 cm height x 20 cm diameter. The migration in soil of the oils and of the metabo... | ['Caproates', 'Hydrogen-Ion Concentration', 'Mineral Oil', 'Oleic Acid', 'Oleic Acids', 'Plant Oils', 'Soil', 'Temperature', 'Water', 'Water Movements'] | 12,476,997 | [['D02.241.081.193', 'D10.251.400.326'], ['G02.300'], ['D02.455.699.500'], ['D10.251.355.325.600.525'], ['D10.251.355.325.600'], ['D10.627.700', 'D20.215.784.750'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Accumulation of chylomicron remnants in homozygous subjects with familial hypercholesterolaemia. | BACKGROUND: Post-prandial lipoprotein kinetics were investigated in subjects who lack functioning low-density lipoprotein (LDL) receptors [homozygous familial hypercholesterolaemia (FH)].METHODS: An oral fat load was given, and chylomicron plasma kinetics was determined by monitoring the clearance of triglyceride, reti... | ['Adolescent', 'Adult', 'Cells, Cultured', 'Chylomicrons', 'Diterpenes', 'Fibroblasts', 'Homozygote', 'Humans', 'Hypercholesterolemia', 'Lipoproteins', 'Middle Aged', 'Postprandial Period', 'Protein Binding', 'Retinyl Esters', 'Skin', 'Vitamin A'] | 9,650,011 | [['M01.060.057'], ['M01.060.116'], ['A11.251'], ['D10.532.183', 'D12.776.521.242'], ['D02.455.849.291'], ['A11.329.228'], ['G05.380.554'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.584.500.500.396'], ['D10.532', 'D12.776.521'], ['M01.060.116.630'], ['G10.261.700'], ['G02.111.679', 'G03.808'], ['D02.241... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Age has no impact on acute and late toxicity of curative thoracic radiotherapy. | BACKGROUND AND PURPOSE: Radiotherapy is a treatment method frequently employed in the management of thoracic tumours. Although the highest incidence of these tumours is found in elderly people, tolerance to radiotherapy is not well documented in older age groups. Many physicians are tempted to alter the radiotherapy pl... | ['Actuarial Analysis', 'Acute Disease', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Body Weight', 'Chi-Square Distribution', 'Chronic Disease', 'Dyspnea', 'Esophageal Neoplasms', 'Esophagitis', 'Female', 'Humans', 'Incidence', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Muscle Weakness', 'Nausea', 'Radiation In... | 9,572,616 | [['E05.318.740.100', 'N05.715.360.750.100', 'N06.850.520.830.100'], ['C23.550.291.125'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E05.318.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Social inequalities and dental caries in six-year-old children from the Netherlands. | OBJECTIVES: The purpose of our study was to investigate the association of different socioeconomic and sociodemographic factors with dental caries in six-year-old children. Furthermore, we applied a district based approach to explore the distribution of dental caries among districts of low and high socioeconomic positi... | ['Adolescent', 'Child', 'Cohort Studies', 'Cross-Sectional Studies', 'Demography', 'Dental Care', 'Dental Caries', 'Educational Status', 'Employment', 'Female', 'Healthcare Disparities', 'Humans', 'Income', 'Logistic Models', 'Male', 'Netherlands', 'Oral Health', 'Parents', 'Pediatric Dentistry', 'Photography, Dental',... | 28,450,065 | [['M01.060.057'], ['M01.060.406'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['E06.170', 'N02.421.240.190'], ['C07.793.720.210'], ['N01.824.196'], ['N01.824.245'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Phenomena and Process... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Activity of crude cold-water extract of the culinary-medicinal oyster mushroom, Pleurotus ostreatus (Jacq.:Fr.) P.Kumm. (higher Basidiomycetes), and timolol maleate on induced ocular hypertension. | Aqueous crude cold-water extract from the fruiting body of the culinary-medicinal oyster mushroom Pleurotus ostreatus was assessed for activity against increased intra-ocular pressure (IOP) in mice. A 0.1% dexamethasone instillation was used to raise the intra-ocular pressure in the animals above the 21-mmHg threshold ... | ['Adrenergic beta-Antagonists', 'Animals', 'Cold Temperature', 'Dexamethasone', 'Glucocorticoids', 'Mice', 'Ocular Hypertension', 'Pleurotus', 'Random Allocation', 'Timolol', 'Water'] | 23,510,215 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['B01.050'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D06.472.040.543', 'D27.505.696.399.472.488'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Dehydroepiandrosterone Stimulation of Osteoblastogenesis in Human MSCs Requires IGF-I Signaling. | Dehydroepiandrosterone (DHEA) is an adrenal steroid that circulates in high concentrations in humans in its sulfated form, DHEAS. Clinical and epidemiological studies suggested that low DHEAS levels may be associated with low bone mass. Previously, we and others showed that the effects of DHEA on the skeleton may be co... | ['Dehydroepiandrosterone', 'Female', 'Gene Expression Regulation', 'Humans', 'Insulin-Like Growth Factor I', 'MAP Kinase Signaling System', 'Male', 'Mesenchymal Stem Cells', 'Mitogen-Activated Protein Kinase 1', 'Osteoblasts', 'Phosphatidylinositol 3-Kinases', 'Receptor, IGF Type 1', 'p38 Mitogen-Activated Protein Kina... | 26,682,953 | [['D04.210.500.054.079.429.625', 'D04.210.500.578.502.400', 'D06.472.040.502.400', 'D06.472.334.851.968.952'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['A11.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of botulinum toxin injections on gait control in spastic stroke patients presenting with a stiff-knee gait. | INTRODUCTION: Botulinum toxin type A (BoNT-A) injections are known to improve walking impairments and activity in spastic hemiparetic stroke patients presenting with a stiff-knee gait [Caty GD, Detrembleur C, Bleyenheuft C, Deltombe T, Lejeune TM. Effect of simultaneous botulinum toxin injections into several muscles o... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Anti-Dyskinesia Agents', 'Biomechanical Phenomena', 'Botulinum Toxins, Type A', 'Female', 'Gait', 'Gait Disorders, Neurologic', 'Humans', 'Male', 'Middle Aged', 'Muscle Spasticity', 'Paresis', 'Stroke', 'Stroke Rehabilitation'] | 19,442,523 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.427.090'], ['G01.154.090', 'G01.374.089'], ['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['E01.370.600.250', 'G11.427.410.568.900.... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Determining cyclooxygenase-2 activity in three different test systems utilizing online-solid phase extraction-liquid chromatography-mass spectrometry for parallel quantification of prostaglandin E(2), D(2) and thromboxane B(2). | Cyclooxygenase-2 (COX-2) catalyzes the formation of PGH2 from arachidonic acid. PGH2 is further converted to different prostaglandins (PG), such as PGE2, PGD2 and TxB2. In this study a rapid online-SPE-LC-MS method for the simultaneous quantification of PGE2, PGD2 and TxB2 streamlined for COX-2 enzyme assays is present... | ['Celecoxib', 'Cell Line', 'Chromatography, Liquid', 'Cyclooxygenase 2', 'Cyclooxygenase 2 Inhibitors', 'Dexamethasone', 'Dinoprostone', 'Humans', 'Indomethacin', 'Lipopolysaccharides', 'Monocytes', 'Prostaglandin D2', 'Pyrazoles', 'Recombinant Proteins', 'Solid Phase Extraction', 'Spectrometry, Mass, Electrospray Ioni... | 25,777,050 | [['D02.065.884.247', 'D02.886.590.700.247', 'D03.383.129.539.160'], ['A11.251.210'], ['E05.196.181.400'], ['D08.811.600.720.750'], ['D27.505.519.389.310.500', 'D27.505.696.663.850.014.040.500.500.500', 'D27.505.954.158.030.500.500', 'D27.505.954.329.030.500.500'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'],... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stepwise abnormality of sex steroid hormone receptors, tumor suppressor gene products (p53 and Rb), and cyclin E in uterine endometrioid carcinoma. | BACKGROUND: In the normal cell cycle, the appropriate interaction of factors such as tumor suppressor gene products (retinoblastoma susceptibility [Rb], p53) and cyclins is essential. Abnormalities in the interaction of these factors may result in malignant transformation of the cell. Malignant transformation of the en... | ['Adult', 'Aged', 'Carcinoma, Endometrioid', 'Cyclins', 'Endometrial Neoplasms', 'Female', 'Humans', 'Immunoenzyme Techniques', 'Menopause', 'Middle Aged', 'Receptors, Estrogen', 'Receptors, Progesterone', 'Receptors, Steroid', 'Retinoblastoma Protein', 'Tumor Suppressor Protein p53'] | 8,625,241 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.025.240', 'C04.588.945.418.948.585.124', 'C13.351.500.056.630.705.331', 'C13.351.937.418.685.331', 'C13.351.937.418.875.200.124', 'C19.391.630.705.331'], ['D12.644.360.262', 'D12.776.167.218', 'D12.776.476.262'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.2... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Management of tracheostomal stenosis. | BACKGROUND: Tracheostomal stenosis following laryngectomy is a distressing complication with major effects on patient rehabilitation. Management ranges from stenting with a prosthetic device to surgical revision. The goal is a widely patent stoma that is amenable to tracheoesophageal puncture.OBJECTIVE: Review the long... | ['Female', 'Humans', 'Laryngectomy', 'Male', 'Middle Aged', 'Reoperation', 'Surgical Flaps', 'Surgical Stomas', 'Trachea', 'Tracheal Stenosis', 'Tracheostomy'] | 10,499,042 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.580.369'], ['M01.060.116.630'], ['E04.690'], ['A10.850.710', 'E07.862.710'], ['A10.850.720'], ['A04.889'], ['C08.907.663'], ['E02.041.750', 'E04.579.935', 'E04.580.900', 'E04.928.780']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Concentrations of urinary 8-hydroxy-2'-deoxyguanosine and 8-isoprostane in women exposed to woodsmoke in a cookstove intervention study in San Marcos, Peru. | Nearly half of the world's population is exposed to household air pollution (HAP) due to long hours spent in close proximity to unvented cooking fires. The effect of woodsmoke exposure on oxidative stress was examined by investigating the association between woodsmoke exposure and biomarkers of DNA oxidation (8-hydroxy... | ["8-Hydroxy-2'-Deoxyguanosine", 'Adult', 'Air Pollution', 'Biomarkers', 'Cooking', 'Creatinine', 'Deoxyguanosine', 'Dinoprost', 'Environmental Exposure', 'Environmental Monitoring', 'Female', 'Household Articles', 'Humans', 'Lipid Peroxidation', 'Oxidative Stress', 'Peru', 'Smoke', 'Wood'] | 24,041,735 | [['D03.633.100.759.590.454.240.500', 'D13.570.230.360.500', 'D13.570.583.454.240.500'], ['M01.060.116'], ['N06.850.460.100'], ['D23.101'], ['J01.576.423.200.200'], ['D03.383.129.308.207'], ['D03.633.100.759.590.454.240', 'D13.570.230.360', 'D13.570.583.454.240'], ['D10.251.355.255.550.400.200', 'D23.469.050.175.725.400... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Importance of detoxifying enzymes in differentiating fibrotic development between SHRSP5/Dmcr and SHRSP rats. | OBJECTIVES: High-fat and -cholesterol diet (HFC) induced fibrotic steatohepatitis in stroke-prone spontaneously hypertensive rat (SHRSP) 5/Dmcr, the fifth substrain from SHRSP, by dysregulating bile acid (BA) kinetics. This study aimed to clarify the histopathological and BA kinetic differences in HFC-induced fibrosis ... | ['Animals', 'Cholesterol, Dietary', 'Diet, High-Fat', 'Disease Progression', 'Fatty Liver', 'Fibrosis', 'Inactivation, Metabolic', 'Liver', 'Male', 'Random Allocation', 'Rats', 'Rats, Inbred SHR'] | 27,209,494 | [['B01.050'], ['D04.210.500.247.808.197.225', 'D10.212.302.347', 'D10.570.938.208.222'], ['G07.203.650.240.267'], ['C23.550.291.656'], ['C06.552.241'], ['C23.550.355'], ['G03.171.450', 'G03.787.225.450', 'G07.690.725.225.450'], ['A03.620'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of varying the length of exposure to polybrominated biphenyls on the development of gamma-glutamyl transpeptidase enzyme-altered foci. | Female Sprague-Dawley rats were fed polybrominated biphenyls (PBBs) for 15 or 140 days after a 70% partial hepatectomy and diethylnitrosamine administration (10 mg/kg body weight) to determine the effect of varying the length of exposure to PBBs on the enhancement of gamma-glutamyl transpeptidase enzyme-altered foci. f... | ['Adipose Tissue', 'Animals', 'Body Weight', 'Dose-Response Relationship, Drug', 'Female', 'Liver', 'Liver Neoplasms, Experimental', 'Microsomes, Liver', 'Polybrominated Biphenyls', 'Rats', 'gamma-Glutamyltransferase'] | 6,140,088 | [['A10.165.114'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G07.690.773.875', 'G07.690.936.500'], ['A03.620'], ['C04.588.274.623.460', 'C04.619.540', 'C06.301.623.460', 'C06.552.697.580', 'E05.598.500.496.750'], ['A11.284.835.540.... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Physiological and pharmacological evaluation of oxytocin-induced milk ejection in mice. | Oxytocin, a posterior pituitary hormone, causes the contraction of the mammary myoepithelial cells that surround the acini. This ejects milk from the acini into the primary mammary ducts. The milk ejection responses by oxytocin have not yet been exactly evaluated in mice. Thus, we present a novel method for quantitativ... | ['Animals', 'Dose-Response Relationship, Drug', 'Female', 'Lactation', 'Mice, Inbred C57BL', 'Oxytocin'] | 32,213,759 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['G08.686.523', 'G08.686.702.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D06.472.699.631.692.433', 'D12.644.548.691.692.433']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Diagnosis of the Paget-von Schroetter syndrome and monitoring of the therapeutic results (author's transl)]. | Streptokinase or Urokinase can lead to complete healing in Paget-von Schroetter Syndrome. This tyne of lysis therapy should be instituted immediately or after the fourteenth postthrombotic day. The diagnosis should be verified by armphlebography. The therapeutic results must be controlled by phlebography in order to po... | ['Axillary Vein', 'Fibrinolytic Agents', 'Humans', 'Radiography', 'Streptokinase', 'Syndrome', 'Thrombosis', 'Urokinase-Type Plasminogen Activator'] | 7,394,181 | [['A07.015.908.077'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['D08.811.277.656.300.775', 'D12.776.124.125.662.537'], ['C23.550.288.500'], ['C14.907.355.830'], ['D08.811.277.656.300.760.910', 'D08.811.277.656.959.350.91... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elevated plasma and vitreous levels of leucine-rich-á2-glycoprotein are associated with diabetic retinopathy progression. | PURPOSE: To investigate the association of plasma and vitreous leucine-rich-á2-glycoprotein (LRG1) with diabetic retinopathy (DR) progression.METHODS: A total of 86 outpatients and 33 inpatients were recruited. Outpatients with type 2 diabetes mellitus (T2DM) were classified as T2DM without DR (n = 22), nonproliferativ... | ['Biomarkers', 'Cross-Sectional Studies', 'Diabetic Retinopathy', 'Disease Progression', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Follow-Up Studies', 'Glycoproteins', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'ROC Curve', 'Vitrectomy', 'Vitreous Body'] | 29,168,314 | [['D23.101'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['C23.550.291.656'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E05.318.372.500.750.249', 'N... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Autophagy defects suggested by low levels of autophagy activator MAP1S and high levels of autophagy inhibitor LRPPRC predict poor prognosis of prostate cancer patients. | MAP1S (originally named C19ORF5) is a widely distributed homolog of neuronal-specific MAP1A and MAP1B, and bridges autophagic components with microtubules and mitochondria to affect autophagosomal biogenesis and degradation. Mitochondrion-associated protein LRPPRC functions as an inhibitor for autophagy initiation to p... | ['Adenocarcinoma', 'Aged', 'Animals', 'Autophagy', 'Histones', 'Humans', 'Male', 'Mice', 'Microtubule-Associated Proteins', 'Neoplasm Proteins', 'PTEN Phosphohydrolase', 'Prognosis', 'Prostatic Neoplasms', 'RNA-Binding Proteins'] | 25,043,940 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['B01.050'], ['G04.011'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.220.600.450', 'D12.776.631.560'], ['D12.776.624'], ['D08.811.277.352.650.850... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Monitoring of firefighters exposure to smoke during fire experiments in Portugal. | Forest fires represent a serious threat to public security in Europe due to the large burned area. Moreover, smoke pollution due to forest fire events is an important public health issue for the communities directly affected, and particularly for the personnel involved in firefighting operations. Aiming to contribute t... | ['Air Pollutants, Occupational', 'Carbon Monoxide', 'Environmental Monitoring', 'Fires', 'Humans', 'Nitrogen Dioxide', 'Occupational Exposure', 'Particle Size', 'Portugal', 'Smoke', 'Volatile Organic Compounds'] | 20,579,737 | [['D27.888.284.101.268'], ['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['N06.850.460.350.080', 'N06.850.780.375'], ['N06.230.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.362.635.600', 'D01.625.550.525', 'D01.650.550.587.625'], ['N06.850.460.350.600'], ['G02.712'], ['Z01.542.727'], ['D20.633.937']... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Attitudes of Pediatricians Regarding Prevention and Treatment of Vitamin D Deficiency. | To determine the adherence of pediatricians to the nationwide 'Vitamin D Prophylaxis Program' and to evaluate their attitudes about vitamin D intake. The study was conducted using the Turkish National Pediatrics Association network. The pediatricians were asked to respond to an online questionnaire that included five q... | ['Attitude of Health Personnel', 'Dietary Supplements', 'Dose-Response Relationship, Drug', 'Humans', 'Infant', 'Infant, Newborn', 'Pediatricians', "Practice Patterns, Physicians'", 'Surveys and Questionnaires', 'Turkey', 'Vitamin D', 'Vitamin D Deficiency', 'Vitamins'] | 27,087,583 | [['F01.100.050', 'N05.300.100'], ['G07.203.300.456', 'J02.500.456'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['M01.526.485.810.758', 'N02.360.810.758'], ['N04.590.374.577', 'N05.300.625'], ['E05.318.308.980', 'N05.715.360.300.800', '... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Complications of cesarean delivery in the massively obese parturient. | OBJECTIVE: The objective of the study was to determine predictors of cesarean delivery morbidity associated with massive obesity.STUDY DESIGN: This was an institutional review board-approved retrospective study of massively obese women (body mass index, > or = 50 kg/m(2)) undergoing cesarean delivery. Bivariable and mu... | ['Blood Loss, Surgical', 'Body Mass Index', 'Cesarean Section', 'Diabetes Complications', 'Drainage', 'Female', 'Humans', 'Maternal Age', 'Obesity, Morbid', 'Patient Readmission', 'Pregnancy', 'Reoperation', 'Retrospective Studies', 'Smoking', 'Surgical Wound Infection', 'Wound Healing'] | 20,678,746 | [['C23.550.414.300', 'C23.550.505.300'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E04.520.252.500'], ['C19.246.099'], ['E02.309', 'E04.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.560', 'N05.715.350.075.550', 'N06.850.490.250.550'], ['C18.654.7... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Caffeic acid phenethyl ester inhibits endothelial tissue factor expression. | Caffeic acid phenethyl ester (CAPE) is a component of honeybee hives with various beneficial properties. Tissue factor (TF), the key trigger of thrombosis, is expressed in human endothelial cells. This study was designed to investigate whether CAPE modulates TF expression in human aortic endothelial cells (HAECs). West... | ['Aorta', 'Caffeic Acids', 'Cells, Cultured', 'Endothelial Cells', 'Fibrinolytic Agents', 'Humans', 'Mitogen-Activated Protein Kinases', 'Phenylethyl Alcohol', 'RNA, Messenger', 'Thromboplastin', 'Tumor Necrosis Factor-alpha', 'Vascular Cell Adhesion Molecule-1'] | 23,727,925 | [['A07.015.114.056'], ['D02.241.223.200.054'], ['A11.251'], ['A11.436.275'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.567', 'D12.644.360.450', 'D12.776.476.450'], ['D02.033.375.650'], ['D13.444.735.544'], ['D12.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Management and assessment of prognosis after gastrocnemius disruption in Thoroughbred foals: 28 cases (1993-2007). | REASONS FOR PERFORMING STUDY: Few studies have evaluated the athletic prognosis of foals affected by gastrocnemius disruption.OBJECTIVE: To examine the diagnosis and management of gastrocnemius disruption in Thoroughbred (TB) foals, determine short-term survival rate and assess future racing performance. The hypothesis... | ['Animals', 'Female', 'Horse Diseases', 'Horses', 'Male', 'Muscle, Skeletal', 'Muscular Diseases', 'Physical Conditioning, Animal', 'Prognosis', 'Retrospective Studies', 'Treatment Outcome'] | 19,803,048 | [['B01.050'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['A02.633.567', 'A10.690.552.500'], ['C05.651', 'C10.668.491'], ['G11.427.410.698.277.280'], ['E01.789'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500'... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
An improved sperm immobilization test based on multiple exposure photography. | An improved method for objective evaluation of results in the complement dependent sperm immobilization test, with the aid of the multiple exposure photography (MEP) method is described. With this method it is possible to determine the percentage of residual motility of spermatozoa quantitatively after incubation with ... | ['Antibodies', 'Complement System Proteins', 'Cytotoxicity Tests, Immunologic', 'Female', 'Humans', 'In Vitro Techniques', 'Infertility', 'Male', 'Photography', 'Sperm Motility', 'Spermatozoa'] | 3,985,254 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.124.486.274'], ['E01.370.225.812.160', 'E05.200.812.160', 'E05.478.594.160', 'E05.940.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['C12.294.365', 'C13.351.500.365'], ['E01.370.350.600', 'E05.712'], ['E... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increased ability of tirofiban to maintain its inhibitory effects on the binding of fibrinogen to platelets in blood from patients with and without diabetes mellitus. | OBJECTIVES: Both tirofiban and eptifibatide release rapidly from glycoprotein IIb-IIIa but have different dissociation constants (KD of tirofiban=15 nmol/l, of eptifibatide=120 nmol/l). Binding of fibrinogen to glycoprotein IIb-IIIa is biphasic, forming an initial reversible complex (KD=155-180 nmol/l) and a second mor... | ['Aged', 'Diabetes Mellitus', 'Female', 'Fibrinogen', 'Flow Cytometry', 'Humans', 'In Vitro Techniques', 'Male', 'Platelet Activation', 'Platelet Aggregation Inhibitors', 'Platelet Glycoprotein GPIIb-IIIa Complex', 'Tirofiban', 'Tyrosine'] | 16,374,143 | [['M01.060.116.100'], ['C18.452.394.750', 'C19.246'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of plating media for recovery of total and virulent genotypes of Vibrio vulnificus in U.S. market oysters. | Vibrio vulnificus is the leading cause of seafood associated mortality in the United States and is generally associated with consumption of raw oysters. Two genetic markers have emerged as indicators of strain virulence, 16S rDNA type B (rrnB) and virulence correlated gene type C (vcgC). While much is known about the d... | ['Animals', 'Culture Media', 'Genotype', 'Ostreidae', 'Seasons', 'United States', 'Vibrio vulnificus', 'Virulence Factors', 'rRNA Operon'] | 24,184,610 | [['B01.050'], ['D27.720.470.305', 'E07.206'], ['G05.380'], ['B01.050.500.644.080.643'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['Z01.107.567.875'], ['B03.440.450.900.859.900', 'B03.660.250.830.830.900'], ['D23.946.896'], ['G05.360.340.024.686.817', 'G05.360.340.358.207.500.817']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Effect of hepatic portal injection of ouabain on the hepato-sympathoadrenal reflex. | The purpose of the present investigation was to evaluate the effects of an intraportal injection of ouabain (2 mg/kg), an inhibitor of the sodium-potassium pump, on plasma catecholamine response in unrestrained normally fed rats with and without an intact hepatic vagus nerve. Three groups of rats were submitted to two ... | ['Adrenal Glands', 'Afferent Pathways', 'Animals', 'Blood Glucose', 'Epinephrine', 'Injections, Intravenous', 'Liver', 'Male', 'Norepinephrine', 'Ouabain', 'Portal Vein', 'Rats', 'Rats, Sprague-Dawley', 'Reflex', 'Sodium-Potassium-Exchanging ATPase', 'Sympathetic Nervous System'] | 9,617,999 | [['A06.300.071'], ['A08.612.220'], ['B01.050'], ['D09.947.875.359.448.500'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['A03.620'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.2... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gastrointestinal and other clinical manifestations in 17 children with congenital disorders of glycosylation type Ia, Ib, and Ic. | OBJECTIVES: The typical signs and symptoms of congenital disorders of glycosylation (CDG) include dysmorphy, failure to thrive, and neurologic abnormalities. However, more and more children diagnosed at a young age are not dysmorphic and do not have neurologic involvement. The authors studied the gastrointestinal and o... | ['Adolescent', 'Adult', 'Age of Onset', 'Alanine Transaminase', 'Blood Coagulation Disorders', 'Child', 'Child, Preschool', 'Congenital Disorders of Glycosylation', 'Duodenum', 'Failure to Thrive', 'Female', 'Glucosyltransferases', 'Glycosylation', 'Hepatomegaly', 'Humans', 'Infant', 'Liver', 'Liver Cirrhosis', 'Male',... | 15,076,627 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['D08.811.913.477.700.100'], ['C15.378.100'], ['M01.060.406'], ['M01.060.406.448'], ['C16.320.565.202.125', 'C18.452.648.202.125'], ['A03.556.124.684.124', 'A03.556.875.249'], ['C23.888.338'], ['D08.811.913.400.450.460'], ['G02.111.158.8... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Teaching and Assessing ED Handoffs: A Qualitative Study Exploring Resident, Attending, and Nurse Perceptions. | INTRODUCTION: The Accreditation Council for Graduate Medical Education requires that residency programs ensure resident competency in performing safe, effective handoffs. Understanding resident, attending, and nurse perceptions of the key elements of a safe and effective emergency department (ED) handoff is a crucial s... | ['Attitude of Health Personnel', 'Clinical Competence', 'Education, Medical, Graduate', 'Emergency Service, Hospital', 'Focus Groups', 'Humans', 'Internship and Residency', 'Interprofessional Relations', 'Medical Staff, Hospital', 'Nursing Staff, Hospital', 'Oregon', 'Organizational Culture', 'Patient Handoff', 'Qualit... | 26,594,273 | [['F01.100.050', 'N05.300.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.358.337.350', 'I02.358.399.350'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Binding to Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2. | Transmitter release at synapses between nerve cells is spatially restricted to active zones, where synaptic vesicle docking, priming, and Ca2+-dependent fusion take place in a temporally highly coordinated manner. Munc13s are essential for priming synaptic vesicles to a fusion competent state, and their specific active... | ['Amino Acid Sequence', 'Animals', 'GTP-Binding Proteins', 'Hippocampus', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Mice', 'Molecular Sequence Data', 'Nerve Tissue Proteins', 'Neurons', 'Rats', 'Sequence Homology, Amino Acid', 'Synapses', 'rab3A GTP-Binding Protein'] | 16,704,978 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360', 'D12.776.476'], ['B01.050.150.900.649.313.992.635.505.500'], ['L01.453.245.667'], ['D12.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Delayed cortical development in fetuses with complex congenital heart disease. | Neurologic impairment is a major complication of complex congenital heart disease (CHD). A growing body of evidence suggests that neurologic dysfunction may be present in a significant proportion of this high-risk population in the early newborn period prior to surgical interventions. We recently provided the first evi... | ['Cerebral Cortex', 'Female', 'Fetus', 'Humans', 'Hypoplastic Left Heart Syndrome', 'Magnetic Resonance Imaging', 'Male', 'Pregnancy'] | 22,977,063 | [['A08.186.211.200.885.287.500'], ['A16.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.240.400.625', 'C14.280.400.625', 'C16.131.240.400.625'], ['E01.370.350.825.500'], ['G08.686.784.769']] | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intersubtest discrepancies on the RBANS: results from the OKLAHOMA study. | The present study provides supplemental data for the Repeatable Battery for the Assessment of Neuropsychological Status (Randolph, 1998) by reporting base rate data on discrepancies between subtests of this measure. These discrepancies are organized by general level of ability and include both age and education correct... | ['Age Factors', 'Aged', 'Cognition', 'Female', 'Geriatric Assessment', 'Humans', 'Longitudinal Studies', 'Male', 'Neuropsychological Tests', 'Reference Values'] | 21,660,759 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['F02.463.188'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', '... | ['Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Left hemicranial hypoplasia in 2 patients with primary progressive aphasia. | BACKGROUND: Primary progressive aphasia (PPA) leads to a gradual and relatively isolated dissolution of language function. The factors that determine the selectivity of the disease process remain unknown. We had speculated that PPA may occasionally arise as a tardive manifestation of genetic or acquired vulnerabilities... | ['Activities of Daily Living', 'Adult', 'Aphasia, Primary Progressive', 'Apolipoproteins E', 'Brain', 'Cognition Disorders', 'Cranial Fossa, Middle', 'Electroencephalography', 'Epilepsy', 'Female', 'Functional Laterality', 'Humans', 'Language', 'Male', 'Middle Aged', 'Nerve Degeneration', 'Tomography, Emission-Computed... | 14,967,776 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['C10.228.140.380.132', 'C10.597.606.150.500.800.100.155', 'C23.888.592.604.150.500.800.100.155', 'F03.615.400.125'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['A08.186.211'], ['F03.615.250'], ['A01.456... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Info... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Acylphloroglucinol derivatives from Hypericum prolificum. | Three new acylphloroglucinol derivatives have been isolated from the hexane extract of the aerial parts of Hypericum prolificum L.: prolificin A (1), prolifenone A (2), and prolifenone B (3). The structures were elucidated on the basis of extensive 2D NMR and MS data. All three compounds were evaluated for in vitro cel... | ['Animals', 'Antineoplastic Agents, Phytogenic', 'Cell Line, Tumor', 'Drug Screening Assays, Antitumor', 'Humans', 'Hypericum', 'Inhibitory Concentration 50', 'Molecular Structure', 'Pennsylvania', 'Phloroglucinol', 'Plants, Medicinal'] | 17,125,240 | [['B01.050'], ['D27.505.954.248.179'], ['A11.251.210.190', 'A11.251.860.180'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.650.940.800.575.912.250.859.625.500'], ['E05.940.350', 'G07.690.936.563'], ['G02.111.570', 'G02.466'], ['Z01... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Detection of lipid-linked peptidoglycan precursors by exploiting an unexpected transpeptidase reaction. | Penicillin-binding proteins (PBPs) are involved in the synthesis and remodeling of bacterial peptidoglycan (PG). Staphylococcus aureus expresses four PBPs. Genetic studies in S. aureus have implicated PBP4 in the formation of highly cross-linked PG, but biochemical studies have not reached a consensus on its primary en... | ['Bacterial Proteins', 'Monosaccharides', 'Oligopeptides', 'Penicillin-Binding Proteins', 'Peptidoglycan', 'Peptidyl Transferases', 'Protein Structure, Tertiary', 'Staphylococcus aureus', 'Uridine Diphosphate N-Acetylmuramic Acid'] | 25,291,014 | [['D12.776.097'], ['D09.947.875'], ['D12.644.456'], ['D08.811.710', 'D12.776.097.545'], ['D09.400.420.700', 'D09.698.718.594', 'D12.644.233.594', 'D12.776.395.560.800', 'D23.050.161.616.594'], ['D08.811.913.050.200.700'], ['G02.111.570.820.709.610'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Accuracy of perceiving blood glucose in IDDM. | Type I (insulin-dependent) diabetic individuals and health professionals often assume that the symptoms of extremely low or high blood glucose (BG) levels can be recognized and, consequently, appropriate treatment decisions can be based on symptom perception. Because no research has documented the validity of these ass... | ['Adult', 'Blood Glucose', 'Diabetes Mellitus, Type 1', 'Female', 'Humans', 'Hyperglycemia', 'Hypoglycemia', 'Male', 'Middle Aged', 'Perception'] | 4,075,939 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.952'], ['C18.452.394.984'], ['M01.060.116.630'], ['F02.463.593']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Methyl bromide production from dissolved organic matter under simulated sunlight irradiation and the important effect of ferric ions. | The oceans play an important role in the biogeochemical cycle of methyl bromide (CH3Br), as not only the sinks but also the sources. However, many uncertainties exist regarding the way of CH3Br generation in the marine environment. To illustrate the possibility of photochemical formation of CH3Br in saline water, its g... | ['Ferric Compounds', 'Humic Substances', 'Hydrocarbons, Brominated', 'Oceans and Seas', 'Photochemical Processes', 'Sunlight'] | 32,067,016 | [['D01.490.100'], ['D02.241.444', 'D02.455.426.559.389.657.377', 'D20.721.500'], ['D02.455.526.368'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.756'], ['G02.740'], ['G01.358.500.505.650.836', 'G01.750.250.650.836', 'G01.750.770.578.836', 'G16.500.275.063.725.525', 'G16.500.750.775.525', 'N06.230.300.100.725.525']... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
HYDROGEN-RICH MEDIUM AMELIORATES LIPOPOLYSACCHARIDE-INDUCED BARRIER DYSFUNCTION VIA RHOA-MDIA1 SIGNALING IN CACO-2 CELLS. | Gastrointestinal barrier dysfunction is associated with the severity and prognosis of sepsis. Hydrogen gas (H2) can ameliorate multiple organ damage in septic animals. Ras homolog gene family member A (RhoA) and mammalian diaphanous-related formin 1 (mDia1) are important to regulate tight junction (TJ) and adherens jun... | ['Adaptor Proteins, Signal Transducing', 'Caco-2 Cells', 'Culture Media', 'Formins', 'Humans', 'Hydrogen', 'Lipopolysaccharides', 'Signal Transduction', 'rhoA GTP-Binding Protein'] | 26,529,665 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['D27.720.470.305', 'E07.206'], ['D05.750.078.730.333', 'D12.776.220.525.333'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.406', 'D01.362.340'], ['D09.400.500', 'D09.698.718.450', '... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Cutaneous artefacts--possibilities for treatment and their limits]. | Factitious disorders (FD) of the skin are emergency calls of the patient, whose psychological problems are mostly unconscious. The therapeutic approach is difficult, because the patient does not accept the necessary psychiatric or psychotherapeutic therapy. Therefore, they remain under the medical care of their dermato... | ['Adult', 'Aged', 'Diagnosis, Differential', 'Factitious Disorders', 'Female', 'Humans', 'Male', 'Middle Aged', 'Psychotherapy', 'Skin Diseases'] | 3,617,857 | [['M01.060.116'], ['M01.060.116.100'], ['E01.171'], ['F03.875.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.754'], ['C17.800']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Expression of superoxide dismutase 2 in breast cancer and its clinical significance]. | OBJECTIVE: To evaluate the expression and prognostic value of superoxide dismutase 2 (SOD2) in breast cancer and explore its possible role in the occurrence and progression of breast cancer.METHODS: We performed bioinformatics analysis of the TCGA data for the expression and clinical relevance of SOD2 in patients with ... | ['Breast Neoplasms', 'Humans', 'Lymphatic Metastasis', 'Prognosis', 'Superoxide Dismutase'] | 32,895,185 | [['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['E01.789'], ['D08.811.682.881']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modern understanding of intussusception and recent trends in management | Intussusception is one of the most common abdominal emergencies in children. The understanding of its aetiology and management has changed significantly over the last decades. Earlier, the hypertrophic Peyer's patches and polyps were considered responsible, but with the knowledge obtained from the lipopolysaccharide-in... | ['Child', 'Enema', 'Glucagon', 'Glucocorticoids', 'Humans', 'Infant', 'Intestinal Obstruction', 'Intussusception', 'Laparoscopy', 'Radiography', 'Recurrence', 'Secondary Prevention', 'Ultrasonography'] | 32,750,021 | [['M01.060.406'], ['E02.319.347'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C06.405.469.531'], ['C06.405.469.531.577'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E01.370.350.700'], ['C2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Effect of trimecaine derivatives and lidocaine on hemodynamics]. | The results of experiments on cats showed that quaternidine, a quaternary ammonium derivative of trimecaine, does not induce significant variations in the hemodynamic parameters, being advantageous in this respect to some well-known antiarrhythmic drugs. LKhT-3-00 (dialkylaminophenylacetamide glutaminate)--a tertiary d... | ['Animals', 'Anti-Arrhythmia Agents', 'Cats', 'Female', 'Hemodynamics', 'Lidocaine', 'Male', 'Quaternary Ammonium Compounds', 'Trimecaine'] | 15,188,755 | [['B01.050'], ['D27.505.954.411.097'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['G09.330.380'], ['D02.065.199.092.500', 'D02.092.146.113.092.500'], ['D01.625.062.500', 'D02.092.877', 'D02.675.276'], ['D02.065.199.092.900', 'D02.092.146.113.092.900']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oxidative cyclization reactions: controlling the course of a radical cation-derived reaction with the use of a second nucleophile. | Construction of new ring systems: Oxidative cyclizations (see picture; RVC=reticulated vitreous carbon) have been conducted that use two separate intramolecular nucleophiles to trap an enol ether-derived radical cation intermediate. The reactions provide a means for rapidly trapping the radical cation intermediate in a... | ['Alkenes', 'Cations', 'Cyclization', 'Electrochemistry', 'Free Radicals', 'Hydrocarbons, Cyclic', 'Molecular Structure', 'Oxidation-Reduction', 'Stereoisomerism'] | 24,254,900 | [['D02.455.326.271'], ['D01.248.497.300'], ['G02.111.180', 'G02.607.133', 'G03.208'], ['H01.181.529.307'], ['D01.339', 'D02.389'], ['D02.455.426'], ['G02.111.570', 'G02.466'], ['G02.700', 'G03.295.531'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The gene for nucleoside diphosphate kinase functions as a mutator gene in Escherichia coli. | Nucleoside diphosphate (NDP) kinase is a key enzyme in the control of cellular concentrations of nucleoside triphosphates, and has been shown to play important roles in various cellular activities such as developmental control, signal transduction and metastasis in eukaryotic systems. In this study, the gene for NDP ki... | ['DNA Replication', 'Deoxyribonucleotides', 'Escherichia coli', 'Genes, Bacterial', 'Mutagenesis', 'Nucleoside-Diphosphate Kinase', 'Phenotype', 'Ribonucleotides'] | 7,490,752 | [['G02.111.225', 'G05.226'], ['D13.695.201'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.558'], ['D08.811.913.696.650.550'], ['G05.695'], ['D13.695.827']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of L-tryptophan treatment on central indoleamine metabolism and short-lasting neurologic disturbances in multiple sclerosis. | Twelve MS patients were treated with L-tryptophan with or without decarboxylase inhibitor for 30 days, and the daily dose was either 1.5 g or 8 g. Tryptophan, 5-HIAA and HVA were analysed from lumbar punctures before and during tryptophan treatment. Clinical evaluation of MS symptoms was performed before, during and at... | ['Adult', 'Benserazide', 'Homovanillic Acid', 'Humans', 'Hydroxyindoleacetic Acid', 'Middle Aged', 'Multiple Sclerosis', 'Tryptophan'] | 1,206,393 | [['M01.060.116'], ['D02.442.175'], ['D02.241.223.601.521'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.066.288.478', 'D03.633.100.473.404.478'], ['M01.060.116.630'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['D12.125.072.050.850', 'D12.125.142.875']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
gcd12 mutations are gcn3-dependent alleles of GCD2, a negative regulator of GCN4 in the general amino acid control of Saccharomyces cerevisiae. | GCD12 encodes a translational repressor of the GCN4 protein, a transcriptional activator of amino acid biosynthetic genes in the yeast Saccharomyces cerevisiae. gcd12 mutations override the requirement for the GCN2 and GCN3 gene products for derepression of GCN4 expression, suggesting that GCN2 and GCN3 function indire... | ['Alleles', 'Amino Acids', 'Chromosome Mapping', 'Cloning, Molecular', 'Gene Expression Regulation', 'Genes, Fungal', 'Genes, Lethal', 'Genes, Regulator', 'Mutation', 'Saccharomyces cerevisiae'] | 2,668,116 | [['G05.360.340.024.340.030'], ['D12.125'], ['E05.393.183'], ['E05.393.220'], ['G05.308'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['G05.360.340.024.340.350'], ['G05.360.340.024.340.425'], ['G05.365.590'], ['B01.300.107.795.785.800', 'B01.300.930.705.655']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Influence of hemodialysis on changes in cerebral artery blood flow velocity in patients with chronic renal failure]. | The effect of hemodialysis on the cerebral circulation have been inadequately studied. Because of repeatability, safety and non-invasiveness transcranial Doppler sonography is well suited for evaluation of cerebral circulation and for estimation of cerebral blood flow during hemodialysis as well. The aim of our study w... | ['Adolescent', 'Adult', 'Aged', 'Blood Flow Velocity', 'Cerebrovascular Circulation', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Laser-Doppler Flowmetry', 'Male', 'Middle Aged', 'Renal Dialysis'] | 8,966,151 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.370.130', 'G09.330.380.630.080'], ['G09.330.100.159'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E01.370.370.475', 'E05.830.500'], ['M01.060.116.630'], ['E02.870.300', 'E02.912.800']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Selective loss of nigral neurons in Pick's disease: a morphometric study. | Loss of neurons from the substantia nigra (SN), which is often encountered in Pick's disease, was quantitatively analyzed in 13 cases of Pick's disease and 19 age-matched controls. On sections from the upper and lower portions of the SN, the pigmented zone (zona compacta) and the non-pigmented zone (zona reticulata) we... | ['Aged', 'Brain', 'Dementia', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neurons', 'Substantia Nigra', 'Zona Reticularis'] | 2,082,655 | [['M01.060.116.100'], ['A08.186.211'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.675', 'A11.671'], ['A08.186.211.132.659.413.656'], ['A06.300.071.140.970']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Transitioning from Unilateral to Bilateral Upper Limb Tremor Therapy for Parkinson's Disease and Essential Tremor Using Botulinum Toxin: Case Series. | Botulinum toxin type A (BoNT-A) injections guided by kinematic analysis for unilateral upper limb essential tremor (ET) and Parkinson's disease (PD) tremor therapy has demonstrated efficacy, improvements in quality of life (QoL) and arm functionality. In this open-label pilot trial, 5 ET and 2 PD participants decided t... | ['Adult', 'Aged', 'Aged, 80 and over', 'Botulinum Toxins, Type A', 'Essential Tremor', 'Female', 'Humans', 'Injections', 'Male', 'Neuromuscular Agents', 'Parkinson Disease', 'Pilot Projects', 'Quality of Life', 'Tremor', 'Upper Extremity'] | 30,262,746 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['C10.228.662.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530'], ['D27.505.696.663.700'], ['C10.228.140.079.862.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Removal of vanadium from industrial wastewater using iron sorbents in batch and continuous flow pilot systems. | This study investigated the removal of vanadium from real industrial wastewater by using six iron materials: commercial iron sorbent (CFH-12), commercial mineral sorbent (AQM), blast furnace sludge (BFS), steel converter sludge (SCS), ferrochrome slag (FeCr) and slag from a steel foundry (OKTO). Batch tests revealed th... | ['Adsorption', 'Humans', 'Industrial Waste', 'Iron', 'Pilot Projects', 'Vanadium', 'Waste Water', 'Water Pollutants, Chemical', 'Water Purification'] | 28,056,356 | [['G01.030', 'G02.020'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.944.420', 'N06.850.460.710.420'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['D01.268.556.920', 'D01.268.956.886', 'D01.552.544.920'], ['D20.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Full-Length Transcriptome Sequencing and the Discovery of New Transcripts in the Unfertilized Eggs of Zebrafish (Danio rerio | Understanding early gene expression in zebrafish embryos is a prerequisite for developmental biology research. In this study, 1,629,447 polymerase reads were obtained from the unfertilized eggs of zebrafish via full-length transcriptome sequencing using the PacBio RS II platform first. Then, 102,920 unique isoforms wer... | ['Animals', 'Cluster Analysis', 'Computational Biology', 'Embryonic Development', 'Gene Expression Profiling', 'Gene Expression Regulation, Developmental', 'Genome', 'Genomics', 'Ovum', 'Sequence Analysis, RNA', 'Transcriptome', 'Whole Exome Sequencing', 'Zebrafish'] | 30,872,328 | [['B01.050'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['H01.158.273.180', 'L01.313.124'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['E05.393.332'], ['G05.308.310'], ['G05.360.340'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['A05.360.490.690', 'A11.497.497', 'A16.690'], ['E05.393... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[Noninvasive identification of left main and triple vessel coronary artery disease using dipyridamole thallium scintigraphy]. | The diagnostic value of dipyridamole thallium scintigraphy for the noninvasive identification of left main (LM) and triple vessel (TV) coronary artery disease (CAD) was evaluated in 615 consecutive patients with known or suspected CAD. One hundred thirty-nine patients had LM or TVCAD; the remaining 476 patients had lim... | ['Adult', 'Aged', 'Aged, 80 and over', 'Coronary Disease', 'Dipyridamole', 'Female', 'Heart', 'Humans', 'Male', 'Methods', 'Middle Aged', 'Multivariate Analysis', 'Radionuclide Imaging', 'Thallium Radioisotopes'] | 8,176,625 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.647.250', 'C14.907.585.250'], ['D03.383.742.175'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['E01.370.350.710', ... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Candidate mechanisms for inhibition of neurotransmitter release by narcotic analgesics and endorphins. | Some neurones are endowed with receptors for endorphins and narcotic analgesics. Activation of these receptors results in a depression of the release of transmitter per impulse. It is currently believed that narcotic analgesics and endorphins depress the stimulus-induced influx of calcium (Ca2+) into the terminal and t... | ['Analgesics, Opioid', 'Calcium', 'Endorphins', 'Models, Biological', 'Nerve Block', 'Neural Inhibition', 'Neuroeffector Junction', 'Receptors, Opioid', 'Synaptic Transmission'] | 6,101,314 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quinine resistant falciparum malaria treated with mefloquine. | Twenty eight adult male patients with acute uncomplicated falciparum malaria which showed RI or RII responses to quinine sulfate at the dosage of 600 mg 8 hourly for 7, 10 or 14 days were treated with a single dose of mefloquine (Lariam); 25 patients received 1000 mg, 2 received 750 mg and 1 received 500 mg. The initia... | ['Administration, Oral', 'Adolescent', 'Adult', 'Animals', 'Body Temperature', 'Cross Reactions', 'Drug Resistance, Microbial', 'Humans', 'Malaria', 'Male', 'Mefloquine', 'Middle Aged', 'Plasmodium falciparum', 'Prospective Studies', 'Quinine'] | 2,098,915 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['G12.122.281'], ['G06.225', 'G07.690.773.984.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.752.530', 'C01.920.875'], ['D03.633.100.810.410'], ['M01.060.116.630'], ['B01.043.075.380.611.561'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Development and evaluation of social cognitive measures related to adolescent physical activity. | BACKGROUND: This study aimed to develop and evaluate the construct validity and reliability of modernized social cognitive measures relating to physical activity behaviors in adolescents.METHODS: An instrument was developed based on constructs from Bandura's Social Cognitive Theory and included the following scales: se... | ['Adolescent', 'Factor Analysis, Statistical', 'Female', 'Humans', 'Male', 'Motor Activity', 'Psychological Tests', 'Reproducibility of Results', 'Self Efficacy', 'Social Behavior', 'Social Support', 'Surveys and Questionnaires'] | 22,975,481 | [['M01.060.057'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', 'G11.427.410.698'], ['F04.711'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['F01.752.747.792.700'], ['F01.145.813'], ['I01.880.853... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Signal transduction pathways of group I metabotropic glutamate receptor-induced long-term depression at sensory spinal synapses. | Activation of spinal group I metabotropic glutamate receptors (mGluRs) may have antinociceptive or pro-nociceptive effects in different pain models. Pharmacological activation of group I mGluRs leads to long-term depression (LTD) of synaptic strength between Adelta-fibers and neurons in lamina II of spinal dorsal horn ... | ['Animals', 'Benzoates', 'Calcium', 'Disease Models, Animal', 'Excitatory Amino Acid Antagonists', 'Female', 'Glycine', 'Intracellular Space', 'Long-Term Synaptic Depression', 'Male', 'Neurons, Afferent', 'Nociceptors', 'Patch-Clamp Techniques', 'Posterior Horn Cells', 'Protein Kinase C', 'Rats', 'Rats, Sprague-Dawley'... | 16,185,811 | [['B01.050'], ['D02.241.223.100', 'D02.455.426.559.389.127'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D27.505.519.625.190.300', 'D27.505.696.577.190.300'], ['D12.125.481'], ['A10.082.750', 'A11.284.430'], ['G11.561.638.355'], ['A08.675.650', 'A11.671.650']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anaphylaxis to subcutaneous neutral protamine Hagedorn insulin with simultaneous sensitization to protamine and insulin. | We report an insulin-treated diabetic patient who suffered, in a 2-month period, three severe anaphylactic reactions immediately after self-administered subcutaneous injections of neutral protamine Hagedorn (NPH) human recombinant-DNA insulin. These reactions consisted of local and systemic symptoms, including dyspnea ... | ['Adult', 'Anaphylaxis', 'Diabetes Mellitus, Type 1', 'Drug Hypersensitivity', 'Humans', 'Hypoglycemic Agents', 'Immunoglobulin E', 'Insulin, Isophane', 'Insulin, Long-Acting', 'Male', 'Protamines', 'Skin Tests'] | 8,837,667 | [['M01.060.116'], ['C20.543.480.099'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C20.543.206', 'C25.100.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.715.548.114.619.312'], ['D06.472.699.587... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Biochemical studies on intramembranous localization of alkaline phosphatase in Bacillus megaterium KM]. | Intramembranous localization of alkaline phosphatase (orthophosphoric monoester phosphohydrolase, alkaline optimum, EC 3, 1, 3, 1; AlPase) was observed biochemically in Bacillus megaterium KM grown in 1% polypeptone medium containing 0.5% NaCl at 37 degrees C under aerobic conditions and harvested at the latter logarit... | ['Alkaline Phosphatase', 'Bacillus megaterium', 'Cell Membrane', 'Sonication'] | 2,518,745 | [['D08.811.277.352.650.035'], ['B03.300.390.400.158.218.500', 'B03.353.500.100.218.500', 'B03.510.100.100.218.500', 'B03.510.415.400.158.218.500', 'B03.510.460.410.158.218.500'], ['A11.284.149'], ['E05.848']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alteration of alpha-tocopherol content in the developing and aging peripheral nervous system: persistence of high correlations with total and specific (n-6) polyunsaturated fatty acids. | In contrast to brain, the sciatic nerve concentration of vitamin E in rats increased rapidly during the postnatal period (approximately fivefold between days 1 and 8), then decreased dramatically (about twofold between days 8 and 30), and further decreased slowly between days 30 and 60 and remained constant up to 2 yea... | ['Aging', 'Animals', 'Fatty Acids', 'Fatty Acids, Monounsaturated', 'Fatty Acids, Unsaturated', 'Osmolar Concentration', 'Rats', 'Rats, Inbred Strains', 'Sciatic Nerve', 'Time Factors', 'Vitamin E'] | 2,338,560 | [['G07.345.124'], ['B01.050'], ['D10.251'], ['D10.251.355.325'], ['D10.251.355'], ['G02.640'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['A08.800.800.720.450.760'], ['G01.910.857'], ['D03.383.663.283.909', 'D03.633.100.150.909']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Generation of virus genetic lineages during an outbreak of poliomyelitis. | Wild poliovirus type 3 isolates collected during the Finnish outbreak (1984 to 1985) in different geographical locations were compared by partial RNA sequencing. The entire 5' non-coding end and a discontinuous part of the capsid coding region were sequenced from 15 isolates. Combining the present sequence data with pr... | ['Antigens, Viral', 'Base Sequence', 'Biological Evolution', 'DNA, Viral', 'Disease Outbreaks', 'Epitopes', 'Finland', 'Genetic Variation', 'Genome, Viral', 'Humans', 'Molecular Sequence Data', 'Poliomyelitis', 'Poliovirus', 'RNA, Viral', 'Sequence Homology, Nucleic Acid'] | 1,717,642 | [['D23.050.327'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045', 'G16.075'], ['D13.444.308.568'], ['N06.850.290'], ['D23.050.550'], ['Z01.542.816.186'], ['G05.365'], ['G05.360.340.358.840'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['C01.207.618.750', 'C01.925.782.68... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Penetration of tobramycin into infected extravascular fluids and its therapeutic effectiveness. | The aminoglycoside antibiotic tobramycin was given intramuscularly to 15 patients with infected body fluids (empyema in five patients, peritonitis in five, peritonitis and empyema in one, tracheobronchitis in three, and infection of the pacemaker pocket in one). The infecting bacteria included Pseudomonas aeruginosa, K... | ['Anti-Bacterial Agents', 'Body Fluids', 'Bronchopneumonia', 'Empyema', 'Enterobacteriaceae Infections', 'Exudates and Transudates', 'Humans', 'Male', 'Pacemaker, Artificial', 'Peritonitis', 'Pseudomonas Infections', 'Staphylococcal Infections', 'Time Factors', 'Tobramycin'] | 864,291 | [['D27.505.954.122.085'], ['A12.207'], ['C01.748.610.127', 'C08.127.509', 'C08.381.677.127', 'C08.730.610.127'], ['C01.830.305', 'C23.550.470.756.305'], ['C01.150.252.400.310'], ['A12.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.305.250.750'], ['C01.463.600', 'C06.844.640'], ['C01.150.252.400.739'], ['... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
On the genus Hydrometra Latreille (Hemiptera: Heteroptera: Hydrometridae) from India with description of two new species . | Two new species of the genus Hydrometra Latreille, 1796, are described from the Oriental Region. Hydrometra cherukolensis sp. nov. is described from Kanyakumari District, Tamil Nadu, India, belongs to the Hydrometra julieni species group, and is closely related to H. julieni Hungerford & Evans, 1934 and H. julienoidea ... | ['Animal Structures', 'Animals', 'Female', 'Heteroptera', 'India', 'Male'] | 24,871,746 | [['A13'], ['B01.050'], ['B01.050.500.131.617.412.420'], ['Z01.252.245.393']] | ['Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Citreoviridin induces triglyceride accumulation in hepatocytes through inhibiting PPAR-á in vivo and in vitro. | Citreoviridin (CIT) is a mycotoxin produced by Penicillum citreonigrum, Aspergillus terreus and Eupenicillium ochrosalmoneum. CIT occurs naturally in moldy rice and corn. CIT is associated with the development of atherosclerosis in the general population. Alteration in hepatic lipid metabolism is a pathogenic factor in... | ['Animals', 'Aurovertins', 'Dose-Response Relationship, Drug', 'Hep G2 Cells', 'Hepatocytes', 'Humans', 'Injections, Intraperitoneal', 'Lipid Metabolism', 'Liver', 'Male', 'Mice', 'Mice, Inbred ICR', 'PPAR alpha', 'Structure-Activity Relationship', 'Triglycerides', 'Tumor Cells, Cultured'] | 28,645,467 | [['B01.050'], ['D03.383.663.075'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.251.860.180.432', 'A11.436.348.500'], ['A11.436.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.490'], ['G03.458'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510', 'B01.05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The autoxidation of iron(II) in aqueous systems: the effects of iron chelation by physiological, non-physiological and therapeutic chelators on the generation of reactive oxygen species and the inducement of biomolecular damage. | The ability of various iron(II)-complexes of biological, clinical and chemical interest to reduce molecular oxygen to reactive oxy-radicals has been investigated using complementary oxygen-uptake studies and e.s.r. techniques. It is demonstrated that although the rate of oxygen reduction by a given iron complex is dire... | ['Cyclic N-Oxides', 'Electron Spin Resonance Spectroscopy', 'Free Radicals', 'Iron', 'Iron Chelating Agents', 'Oxidation-Reduction', 'Oxygen', 'Spin Labels', 'Water'] | 1,648,018 | [['D03.661.243'], ['E05.196.867.519.274'], ['D01.339', 'D02.389'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D27.505.519.914.500.410', 'D27.720.832.500.410'], ['G02.700', 'G03.295.531'], ['D01.268.185.550', 'D01.362.670'], ['D02.389.678'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.9... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-performance liquid chromatography assay of cysteine and homocysteine using fluorosurfactant-functionalized gold nanoparticles as postcolumn resonance light scattering reagents. | Herein, a new postcolumn resonance light scattering (RLS) detection approach coupled with high-performance liquid chromatography (HPLC) was developed to detect cysteine and homocysteine. In the established system, the fluorosurfactant-capped gold nanoparticles (AuNPs) were first employed as postcolumn RLS reagents. The... | ['Chromatography, High Pressure Liquid', 'Cysteine', 'Equipment Design', 'Gold', 'Homocysteine', 'Humans', 'Indicators and Reagents', 'Light', 'Limit of Detection', 'Nanoparticles', 'Scattering, Radiation'] | 23,290,357 | [['E05.196.181.400.300'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['E05.320'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['D02.886.030.498', 'D12.125.166.498'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.410'], ['G01.358.500.505.650', 'G01.590.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Interferon effect on collagen and fibronectin distribution in the extracellular matrix of murine sarcoma virus-transformed cells. | The transformation of murine BALB/c embryonic fibroblasts by murine sarcoma virus, Moloney strain, followed by prolonged treatment with murine interferon, resulted in the appearance of a new cell population (MSV-IF+). These MSV-IF+ cells are characterized by the recovery of a normal phenotype, contact inhibition, and l... | ['Animals', 'Cell Line', 'Cell Transformation, Viral', 'Collagen', 'Extracellular Space', 'Fibronectins', 'Histocytochemistry', 'Interferons', 'Mice', 'Mice, Inbred BALB C', 'Mutation', 'Phenotype', 'Sarcoma Viruses, Murine'] | 6,167,350 | [['B01.050'], ['A11.251.210'], ['C04.697.098.500.160', 'C23.550.727.098.500.160', 'G06.920.143'], ['D05.750.078.280', 'D12.776.860.300.250'], ['A10.082.500', 'A11.284.295'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Emergence of Monkeypox - West and Central Africa, 1970-2017. | The recent apparent increase in human monkeypox cases across a wide geographic area, the potential for further spread, and the lack of reliable surveillance have raised the level of concern for this emerging zoonosis. In November 2017, the World Health Organization (WHO), in collaboration with CDC, hosted an informal c... | ['Africa, Central', 'Africa, Western', 'Communicable Diseases, Emerging', 'Humans', 'Monkeypox'] | 29,543,790 | [['Z01.058.290.100'], ['Z01.058.290.190'], ['C01.221.500', 'C23.550.291.531.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.925.256.743.615', 'C22.735.750', 'C22.795.600']] | ['Geographicals [Z]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
On-target fraction collection for the off-line coupling of capillary isoelectric focusing with matrix-assisted laser desorption/ionization mass spectrometry. | In the present work, we describe a collection system for the off-line coupling of capillary isoelectric focusing (CIEF) with matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. In this system, the capillary effluent is directly deposited in fractions onto the MALDI target via the u... | ['Indicators and Reagents', 'Isoelectric Focusing', 'Molecular Weight', 'Proteins', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Spectrophotometry, Ultraviolet'] | 11,803,541 | [['D27.720.470.410'], ['E05.196.401.663', 'E05.301.300.663'], ['G02.494'], ['D12.776'], ['E05.196.566.755'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevention of infection with tobramycin-containing bone cement or systemic cefazolin in an animal model. | We investigated in an animal model the efficacy of tobramycin-containing bone cement and systemic cefazolin for infection prophylaxis. In 18 female rabbits, the femoral cavity was inoculated with Staphylococcus aureus before injection of bone cement. The first group of six rabbits received tobramycin-containing Simplex... | ['Animals', 'Anti-Bacterial Agents', 'Antibiotic Prophylaxis', 'Arthritis, Infectious', 'Blood Sedimentation', 'Bone Cements', 'Cefazolin', 'Cephalosporins', 'DNA, Bacterial', 'Drug Evaluation, Preclinical', 'Female', 'Femur', 'Injections, Intravenous', 'Materials Testing', 'Methylmethacrylate', 'Models, Animal', 'Poly... | 11,033,554 | [['B01.050'], ['D27.505.954.122.085'], ['E02.319.162.150', 'E02.319.703.150'], ['C01.100', 'C05.550.114.099'], ['E01.370.225.625.125', 'E05.200.625.125'], ['D05.750.716.822.300', 'D25.720.716.822.300', 'D27.720.102.158', 'J01.637.051.720.716.822.300'], ['D02.065.589.099.249.160', 'D02.886.665.074.160', 'D03.633.100.300... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Using discrete choice experiments to go beyond clinical outcomes when evaluating clinical practice. | BACKGROUND: This study builds on the results of a randomized controlled trial concerned with examining the effect of reducing waiting times on the health status of patients referred for non-urgent rheumatology opinion. No difference in clinical outcomes was found between a 'fast-track' and 'ordinary' appointment system... | ['Clinical Medicine', 'Female', 'Financing, Personal', 'Humans', 'Male', 'Middle Aged', 'Patient Satisfaction', 'Referral and Consultation', 'Rheumatology', 'State Medicine', 'Surveys and Questionnaires', 'Treatment Outcome', 'United Kingdom', 'Waiting Lists'] | 16,011,645 | [['H02.403.200'], ['N03.219.559'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600'], ['N04.452.758.849'], ['H02.403.429.730'], ['N03.349.550.902', 'N03.858'], ['E05.318.308.980', 'N05.715.360... | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Fatal cardiovascular disease and cutis laxa following acute febrile neutrophilic dermatosis. | Acute neutrophilic dermatosis (Sweet syndrome) is a benign self-limited disease in adults. A child with apparent evolution of acute neutrophilic dermatosis to postinflammatory cutis laxa and elastolysis then developed fatal vascular involvement. One other patient with postinflammatory cutis laxa with aortic regurgitati... | ['Acute Disease', 'Cardiovascular Diseases', 'Cardiovascular System', 'Cutis Laxa', 'Female', 'Humans', 'Infant', 'Neutrophils', 'Skin', 'Skin Diseases', 'Syndrome'] | 6,822,929 | [['C23.550.291.125'], ['C14'], ['A07'], ['C16.320.850.180', 'C17.300.230', 'C17.800.827.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['A17.815'], ['C17.800'], ['C23... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[High intensity focused ultrasound in localized prostate cancer]. | Despite a follow-up too short to allow a relevant assessment of the HIFU efficacy in terms of definitive cure of localized prostate cancer, the last published results from the European multicentric study and from Gelet may consider the HIFU treatment as a valuable alternative option for well differentiated tumors, with... | ['Biopsy', 'Combined Modality Therapy', 'Humans', 'Life Expectancy', 'Male', 'Prognosis', 'Prostate-Specific Antigen', 'Prostatic Neoplasms', 'Radiotherapy', 'Treatment Outcome', 'Ultrasonic Therapy'] | 16,168,696 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.450', 'N01.224.935.464', 'N06.850.505.400.975.450', 'N06.850.520.308.985.450'], ['E01.789'], ['D... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Effects of Sexual Intercourse on Suicidal Behaviors among Adolescents in South Korea]. | PURPOSE: For the current article an examination was done as to whether engaging in sexual intercourse before or during adolescence has a negative impact on the suicidal behaviors of suicide ideation, suicide attempt, and suicide lethality and whether the impact varies according to the context of sexual intercourse and/... | ['Adolescent', 'Adolescent Behavior', 'Female', 'Humans', 'Internet', 'Male', 'Republic of Korea', 'Risk Factors', 'Sex Factors', 'Sex Offenses', 'Sexual Behavior', 'Social Class', 'Suicidal Ideation', 'Suicide, Attempted', 'Surveys and Questionnaires'] | 25,947,180 | [['M01.060.057'], ['F01.145.022'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['Z01.252.474.557.750'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['N05.715.350.675', 'N06.850.490.875'], ['I01.198... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Isolation of protein uH2A using a one step preparative gel electrophoresis. | A one step electrophoretic procedure for the isolation of protein uH2A has been devised which may improve the overall yield. The improvement involves elimination of intermediate steps which might result in the decrease of the yield. The method may serve as an alternate to the conventional methods and can also be used s... | ['Animals', 'Chromatin', 'Chromosomal Proteins, Non-Histone', 'Electrophoresis, Polyacrylamide Gel', 'Histones', 'Liver', 'Rats', 'Spectrophotometry'] | 6,483,804 | [['B01.050'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D12.776.660.235', 'D12.776.664.235'], ['E05.196.401.402', 'E05.301.300.319'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.700'], ['E05.196.712.726', 'E... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enhancement of green electroluminescence from nanocrystalline silicon by wet and dry processes. | Correlation between defects and luminescence property from electroluminescent (EL) device composed of nanocrystalline silicon (nc-Si) prepared by wet and dry processes such as hydrofluoric (HF) acid solution treatment and annealing have investigated using electron spin resonance and EL measurements. The EL device using... | ['Color', 'Electrochemistry', 'Electron Spin Resonance Spectroscopy', 'Luminescence', 'Models, Molecular', 'Nanostructures', 'Silicon', 'Spectroscopy, Fourier Transform Infrared', 'Water'] | 16,573,095 | [['G01.590.540.199'], ['H01.181.529.307'], ['E05.196.867.519.274'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.750.250.650.665', 'G01.750.770.578.665'], ['E05.599.595'], ['J01.637.512'], ['D01.268.513.937'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['D01.045.250.875', 'D01.248.497.158.459.650', ... | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
An ecological correlation study of late age-related macular degeneration and the complement factor H Y402H polymorphism. | PURPOSE: To investigate whether variation in the distribution of the risk allele frequency of the Y402H single-nucleotide polymorphism (SNP) across various ethnicities and geographic regions reflects differences in the prevalence of late age-related macular degeneration (AMD) in those ethnicities.METHODS: Published dat... | ['Aged', 'Complement Factor H', 'Ethnic Groups', 'Gene Frequency', 'Geography', 'Humans', 'Macular Degeneration', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Prevalence', 'Risk Assessment'] | 20,042,653 | [['M01.060.116.100'], ['D12.776.124.486.274.920.325.200', 'D12.776.124.790.223.200', 'D12.776.377.715.182.200'], ['M01.686.754', 'N01.224.317'], ['G05.330'], ['H01.277.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.768.585.439'], ['M01.060.116.630'], ['G05.365.795.598'], ['E05.318.308.985.525.750', 'N01.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
T-cell receptor gene therapy targeting melanoma-associated antigen-A4 by silencing of endogenous TCR inhibits tumor growth in mice and human. | Genetically engineered T cells expressing a T-cell receptor (TCR) are powerful tools for cancer treatment and have shown significant clinical effects in sarcoma patients. However, mismatch of the introduced TCR á/â chains with endogenous TCR may impair the expression of transduced TCR, resulting in an insufficient anti... | ['Adoptive Transfer', 'Animals', 'Antigens, Neoplasm', 'Cell Line, Tumor', 'Cell Proliferation', 'Female', 'Gene Silencing', 'Genetic Therapy', 'HLA-A Antigens', 'Humans', 'Interferon-gamma', 'Leiomyosarcoma', 'Lymphocytes', 'Melanoma', 'Mice, Inbred NOD', 'Mice, SCID', 'Neoplasm Proteins', 'Receptors, Antigen, T-Cell'... | 31,209,257 | [['E02.095.465.425.400.330.050', 'E05.478.550.520.050'], ['B01.050'], ['D23.050.285'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G05.308.203.374'], ['E02.095.301', 'E05.393.420.301'], ['D12.776.395.550.489.400', 'D12.776.543.550.439.400', 'D23.050.301.500.100.400', 'D23.050.301.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stimulus level effects on speech-evoked obligatory cortical auditory evoked potentials in infants with normal hearing. | OBJECTIVE: To determine stimulus level effects on speech-evoked cortical auditory evoked potentials (CAEPs) in infants for a low (/m/) and high (/t/) frequency speech sound.METHODS: CAEPs were recorded for two natural speech tokens, /m/ and /t/. Participants were 16 infants aged 3-8months with no risk factors for heari... | ['Acoustic Stimulation', 'Auditory Cortex', 'Evoked Potentials, Auditory', 'Female', 'Hearing', 'Humans', 'Infant', 'Male', 'Speech', 'Speech Perception'] | 23,117,114 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['A08.186.211.200.885.287.500.814.249', 'A08.186.211.200.885.287.500.863.297'], ['G07.265.216.500.370', 'G07.888.250', 'G11.561.200.500.370'], ['F02.830.816.263', 'G07.888.500', 'G11.561.790.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.14... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Biomimetic total syntheses of borreverine and flinderole alkaloids. | Dimeric indole alkaloids represent a structurally unique class of natural products having interesting biological activities. Recently, we reported the first total synthesis of flinderoles B and C, structurally unique and potent antimalarial natural products. Central to the design of the approach and by virtue of a one-... | ['Alkaloids', 'Antimalarials', 'Biological Products', 'Biomimetics', 'Cycloaddition Reaction', 'Dimerization', 'Indole Alkaloids', 'Indoles', 'Stereoisomerism'] | 24,044,378 | [['D03.132'], ['D27.505.954.122.250.100.085'], ['D20.215'], ['H01.158.550.100', 'J01.897.120.100'], ['E05.197.406', 'J01.897.836.249.374'], ['G02.206', 'G03.230'], ['D03.132.436', 'D03.633.100.473.402', 'D03.633.100.496.500.500'], ['D03.633.100.473'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Can we predict allergen-induced asthma in patients with allergic rhinitis? | BACKGROUND: A high percentage of patients with allergic rhinitis (AR) exhibit signs of bronchial hyperreactivity (BHR), and approximately 30% may develop asthma later in life.OBJECTIVE: The aim of this study was to identify predictors for allergen-induced asthma in patients with AR.METHODS: Hundred patients with AR sel... | ['Adolescent', 'Adult', 'Allergens', 'Asthma', 'Bronchial Hyperreactivity', 'Bronchial Provocation Tests', 'Case-Control Studies', 'Exhalation', 'Female', 'Humans', 'Immunoglobulin E', 'Male', 'Nitric Oxide', 'Prognosis', 'ROC Curve', 'Rhinitis, Allergic', 'Skin Tests', 'Surveys and Questionnaires', 'Young Adult'] | 25,270,425 | [['M01.060.057'], ['M01.060.116'], ['D23.050.063'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C08.127.210'], ['E01.370.386.700.125'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G09.772.705.700.275'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dynamic light-activated control of local chemical concentration in a fluid. | This article reports a method for controlling the chemical concentration in a localized region of a fluid using optoelectrofluidic mechanisms. Optoelectrofluidic fluorescence microscopy (OFM), in which an optoelectrofluidic device is integrated into a conventional fluorescence microscope, allows both modulation and det... | ['Animals', 'Cattle', 'Dextrans', 'Electricity', 'Fluorescein-5-isothiocyanate', 'Fluoresceins', 'Light', 'Microscopy, Fluorescence', 'Serum Albumin, Bovine', 'Static Electricity'] | 19,496,599 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D05.750.078.562.272', 'D09.698.365.272'], ['G01.358.500.249'], ['D02.455.426.779.347.400', 'D02.500.375.250', 'D02.886.250.250', 'D03.633.300.953.275.400', 'D04.711.347.400'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['G01.358.500.505.650', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Magnetic resonance imaging study of effects of accommodation on human lens morphological characters]. | OBJECTIVE: To evaluate the effects of accommodation on lens morphological characters.METHODS: From January 2011 to June 2011, magnetic resonance images of eyes were acquired from 30 subjects aged 20 to 24 years during accommodation and at rest. The optimal images were analyzed by Autocad 2010 to obtain the total lens c... | ['Accommodation, Ocular', 'Adult', 'Female', 'Humans', 'Lens, Crystalline', 'Magnetic Resonance Imaging', 'Male', 'Young Adult'] | 24,401,623 | [['G14.010'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.060.500'], ['E01.370.350.825.500'], ['M01.060.116.815']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
BMI1 sustains human glioblastoma multiforme stem cell renewal. | Glioblastoma multiforme (GBM) is one of the most common and aggressive types of brain tumors. In GBM, a subpopulation of CD133-positive cancer initiating cells displays stem cell characteristics. The Polycomb group (PcG) and oncogene BMI1 is part of the Polycomb repressive complex 1 (PRC1) that regulates gene expressio... | ['AC133 Antigen', 'Analysis of Variance', 'Animals', 'Antigens, CD', 'Apoptosis', 'Brain Neoplasms', 'Cell Differentiation', 'Cell Line, Tumor', 'Cell Transdifferentiation', 'Cell Transformation, Neoplastic', 'Cells, Cultured', 'Chromatin Immunoprecipitation', 'DNA-Binding Proteins', 'Disease Models, Animal', 'Enhancer... | 19,605,626 | [['D12.776.395.550.007', 'D12.776.543.550.023'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['G04.146.954.035'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['G04.152'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.356'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Where is the popular mandate? A reply to conventional wisdom. | Current federal policies include substantial cuts in government expenditures for health programs and for care of the poor, elderly, and handicapped, and the weakening of government regulations in health and medical care. These policies are presented by many political, academic, and medical leaders as responding to a po... | ['Financing, Government', 'Health Expenditures', 'Public Opinion', 'Public Policy', 'Taxes', 'United States'] | 6,403,478 | [['N03.219.521.346'], ['N03.219.151.450', 'N05.300.385'], ['I01.880.630.548'], ['I01.655.500.608', 'I01.880.604.825.608', 'N03.623.500.608'], ['N03.219.900'], ['Z01.107.567.875']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
The effect of the flattening filter on photoneutron production at 10 MV in the Varian TrueBeam linear accelerator. | PURPOSE: Neutrons are an unavoidable by-product of high-energy radiation therapy treatments that deliver unwanted nontarget dose to patients. Use of flattening-filter-free (FFF) photon beams has been shown to significantly reduce photoneutron production per monitor unit (MU) of dose delivered. The purpose of this inves... | ['Neutrons', 'Particle Accelerators', 'Photons'] | 30,141,186 | [['G01.249.660.250'], ['E07.710.680'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Digital language death. | Of the approximately 7,000 languages spoken today, some 2,500 are generally considered endangered. Here we argue that this consensus figure vastly underestimates the danger of digital language death, in that less than 5% of all languages can still ascend to the digital realm. We present evidence of a massive die-off ca... | ['Humans', 'Linguistics'] | 24,167,559 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.559.598']] | ['Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The association between serological markers for Chlamydophila pneumoniae and the development of abdominal aortic aneurysm. | BACKGROUND: To investigate the association between serological markers for Chlamydophila pneumoniae (Cpn) and the development of abdominal aortic aneurysm (AAA) in a population-based case-control study.METHODS: A screening for AAA among 65-75-year-old men and women was performed in a population with high prevalence of ... | ['Aged', 'Antibodies, Bacterial', 'Aortic Aneurysm, Abdominal', 'Case-Control Studies', 'Chi-Square Distribution', 'Chlamydophila Infections', 'Chlamydophila pneumoniae', 'Female', 'Fluorescent Antibody Technique', 'Humans', 'Immunoglobulin A', 'Immunoglobulin G', 'Male', 'Mass Screening', 'Risk Assessment', 'Risk Fact... | 21,126,854 | [['M01.060.116.100'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Clinical and functional outcome of unicompartmental knee arthroplasty: influence of the mechanical axis correction]. | OBJECTIVES: Clinical and functional outcome of the knee after Unicompartmental Knee Arthroplasty (UKA) and its correlation with lower limb mechanical axis correction.MATERIAL AND METHODS: We have reviewed the outcome of 29 UKA, corresponding to 29 patients, with an average follow-up of 4.5 years (3-6 years). The distri... | ['Aged', 'Arthroplasty, Replacement, Knee', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Osteoarthritis, Knee', 'Recovery of Function', 'Retrospective Studies', 'Treatment Outcome'] | 23,177,940 | [['M01.060.116.100'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['C05.550.114.606.500', 'C05.799.613.500'], ['G16.757'], ['E05.318.372.500.500.500', 'E05.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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