Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Receptor-mediated hydrolysis of plasma membrane messenger PIP2 leads to K+-current desensitization. | Phosphatidylinositol bisphosphate (PIP2) directly regulates functions as diverse as the organization of the cytoskeleton, vesicular transport and ion channel activity. It is not known, however, whether dynamic changes in PIP2 levels have a regulatory role of physiological importance in such functions. Here, we show in ... | ['Acetylcholine', 'Animals', 'Animals, Newborn', 'COS Cells', 'Cell Membrane', 'Cells, Cultured', 'Electric Conductivity', 'Enzyme Activation', 'ErbB Receptors', 'Estrenes', 'G Protein-Coupled Inwardly-Rectifying Potassium Channels', 'Heart Atria', 'Heterotrimeric GTP-Binding Proteins', 'Hydrolysis', 'Ion Channel Gatin... | 10,934,471 | [['D02.092.211.111'], ['B01.050'], ['B01.050.050.282'], ['A11.251.210.172.500', 'A11.329.228.220'], ['A11.284.149'], ['A11.251'], ['G01.358.500.249.277'], ['G02.111.263', 'G03.328'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['D04.210.500.365.415'], ['D12.776.157... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessing Medicare beneficiaries' readiness to make informed health plan choices. | The Transtheoretical Model (TTM, the "stage model") can guide development of programs to increase Medicare beneficiaries' readiness to make informed health plan choices. In this study, TTM staging algorithms were developed to assess readiness to engage in three types of informed choice: (1) learning about the Medicare ... | ['Aged', 'Algorithms', 'Attitude to Health', 'Centers for Medicare and Medicaid Services, U.S.', 'Comprehension', 'Consumer Advocacy', 'Decision Making', 'Health Maintenance Organizations', 'Health Services Research', 'Humans', 'Information Services', 'Learning', 'Medicare Part B', 'Medicare Part C', 'Models, Statistic... | 12,500,365 | [['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['F01.100.150', 'N05.300.150'], ['I01.409.418.750.600.310', 'N03.540.348.500.500.600.550'], ['F02.463.188.357'], ['I01.880.604.473.368', 'N03.706.437.368'], ['F02.463.785.373'], ['N03.219.521.576.343.800.400', 'N03.219.521.576.343.925.400', 'N04.452.758.244.425', 'N04.5... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', '... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
At-home bleaching system: effect on gingival tissue. | This study evaluated the effects of an at-home vital bleaching system on gingival responses over a 6-week period. Objective measures were utilized to measure and monitor gingival inflammation over this period of time. Vital bleaching was performed as follows: (1) bleaching gel in a prefabricated mouthguard and (2) an a... | ['Adult', 'Carbamide Peroxide', 'Dental Devices, Home Care', 'Dentifrices', 'Drug Combinations', 'Female', 'Gels', 'Gingiva', 'Gingivitis', 'Humans', 'Male', 'Middle Aged', 'Periodontal Index', 'Peroxides', 'Tooth Bleaching', 'Urea'] | 1,389,353 | [['M01.060.116'], ['D01.248.497.158.685.750.318', 'D01.339.431.374.318', 'D01.650.550.750.300', 'D02.065.950.278', 'D02.389.338.154'], ['E06.186.250', 'E06.761.726.292', 'E07.222.250'], ['D25.376', 'D27.720.269.380', 'J01.637.051.376'], ['D26.310'], ['D20.280.320', 'D26.255.165.320'], ['A14.549.167.646.480'], ['C01.408... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Cyclooxygenase-2 inhibition for the prophylaxis and treatment of preinvasive breast cancer in a her-2/neu mouse model. | Ductal carcinoma in situ (DCIS) is the most common form of preinvasive breast cancer. Several molecular alterations have been identified in DCIS. Among them, cyclooxygenase 2 (COX-2) overexpression has been shown in 60% to 80% of DCIS cases. Celecoxib is a nonsteroidal anti-inflammatory drug that selectively inhibits C... | ['Animals', 'Antineoplastic Agents', 'Apoptosis', 'Breast Neoplasms', 'Carcinoma in Situ', 'Carcinoma, Ductal, Breast', 'Celecoxib', 'Cyclooxygenase 2', 'Dinoprostone', 'Disease Models, Animal', 'Disease Progression', 'Enzyme Inhibitors', 'Female', 'Genes, erbB-2', 'Immunohistochemistry', 'Mice', 'Mice, Transgenic', 'P... | 20,103,725 | [['B01.050'], ['D27.505.954.248'], ['G04.146.954.035'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.240'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['D02.065.884.247', 'D02.886.590.700.247', 'D03.383.129.539.160'], ['D08.811.600.720.750'], ['D10.251... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Implementation of nuchal translucency image-scoring method during ongoing audit. | OBJECTIVE: The aim of this study was to evaluate the contribution of an ongoing audit, using the image-scoring method, to the quality of nuchal translucency images and to set the basic standards required from the examiners.DESIGN: Evaluation of nuchal translucency images, before, during and after the implementation of ... | ['Analysis of Variance', 'Bias', 'Down Syndrome', 'Female', 'Humans', 'Mass Screening', 'Medical Audit', 'Neck', 'Practice Guidelines as Topic', 'Pregnancy', 'Pregnancy Trimester, First', 'Prospective Studies', 'Reproducibility of Results', 'Retrospective Studies', 'Single-Blind Method', 'Ultrasonography, Prenatal'] | 10,658,276 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['N05.715.350.150', 'N06.850.490.500'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.30... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Predicting nutrition-associated complications for patients undergoing gastrointestinal surgery. | We studied 202 patients admitted to two major teaching hospitals for planned gastrointestinal surgery to assess the ability of several techniques of nutritional assessment to predict major postoperative complications (infection and/or wound problems). Subjective global assessment (SGA) and albumin were both of predicti... | ['Female', 'Gastrointestinal Diseases', 'Humans', 'Male', 'Middle Aged', 'Nutritional Status', 'Postoperative Complications', 'Predictive Value of Tests', 'Prospective Studies', 'Serum Albumin'] | 3,656,631 | [['C06.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G07.203.650.650', 'N01.224.425.525'], ['C23.550.767'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['D12.776... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Influence of unilateral motor behaviors on the judgment of valenced stimuli. | Two experiments were conducted so as to examine how different motor activations (unilateral contraction and extension-flexion paradigms) of the motivational systems of approach and avoidance influenced participants' evaluations of valenced stimuli (figurative expressions and everyday life pictures). The results of the ... | ['Adolescent', 'Adult', 'Affect', 'Arm', 'Attention', 'Concept Formation', 'Decision Making', 'Exercise', 'Female', 'Functional Laterality', 'Humans', 'Judgment', 'Kinesthesis', 'Male', 'Motivation', 'Motor Skills', 'Photic Stimulation'] | 18,472,041 | [['M01.060.057'], ['M01.060.116'], ['F01.470.047'], ['A01.378.800.075'], ['F02.830.104.214'], ['F02.463.785.233'], ['F02.463.785.373'], ['G11.427.410.698.277', 'I03.350'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.785.626'], ['F02.830.816.541.504', 'G11.561.790.5... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Changes in Serum Lipid Levels During Pregnancy and Association With Neonatal Outcomes: A Large Cohort Study. | BACKGROUND: This study is aimed to characterize changes in serum lipid levels throughout pregnancy and explore the association between lipid levels and neonatal outcomes.METHODS: This study included singleton pregnancy women who received regular prenatal care and delivered at Beijing Obstetrics and Gynecology Hospital ... | ['Adult', 'Birth Weight', 'Cohort Studies', 'Female', 'Fetal Macrosomia', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Lipids', 'Pregnancy', 'Pregnancy Outcome', 'Pregnancy Trimester, First', 'Pregnancy Trimester, Third', 'Premature Birth', 'Risk Factors', 'Triglycerides'] | 29,316,857 | [['M01.060.116'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C13.703.170.500', 'C13.703.277.570', 'C13.703.726.570', 'C16.300.570', 'C19.246.099.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Epitope mapping and use of epitope-specific antisera to characterize the VP5* binding site in rotavirus SA11 NSP4. | Rotavirus (RV) is the leading cause of infantile gastroenteritis worldwide. RV nonstructural protein 4 (NSP4), the first characterized viral enterotoxin, is a 28-kDa glycoprotein that has pleiotropic functions in RV infection and pathogenesis. NSP4 has multiple forms enabling it to perform its different functions. Diss... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Antibody Specificity', 'Binding Sites', 'Cell Line', 'Enzyme-Linked Immunosorbent Assay', 'Epitope Mapping', 'Epitopes', 'Glycoproteins', 'Humans', 'Mice', 'Models, Molecular', 'Molecular Sequence Data', 'Peptide Fragments', 'Rabbits', 'Rotavirus', 'Surface ... | 18,164,740 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.100'], ['G02.111.570.120'], ['A11.251.210'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Fear, familiarity, and the perception of risk: a quantitative analysis of disaster-specific concerns of paramedics. | INTRODUCTION: Paramedics play an integral role in the response to and management of disasters and mass casualty events. Providing a core component of the front line response to disasters, paramedics potentially expose themselves to a variety of health and safety risks, including physical injury, death, communicable dis... | ['Accidents', 'Adult', 'Allied Health Personnel', 'Attitude of Health Personnel', 'Australia', 'Disaster Planning', 'Disasters', 'Fear', 'Female', 'Health Care Surveys', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', 'Occupational Health', 'Perception', 'Psychometrics', 'Relief Work', 'Risk A... | 21,402,826 | [['N06.850.135'], ['M01.060.116'], ['M01.526.485.067', 'N02.360.067'], ['F01.100.050', 'N05.300.100'], ['Z01.639.100', 'Z01.678.100.373'], ['N06.230.100.035'], ['N06.230.100'], ['F01.470.361'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['F01.100.150... | ['Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[The MN typing of whole blood and bloodstains by the method of one-step sandwich ELISA]. | The samples of whole blood and bloodstain were MN-typed by the method of one-step sandwich ELISA, monoclonal antibodies include anti-M, N and glycern-protein. The lowest sample amount in this study is: for whole blood is 0.065 microliter, for bloodstain about 10 to 50 ng. 455 cases of fresh blood and 200 cases of fresh... | ['Antibodies, Monoclonal', 'Antigens', 'Blood Grouping and Crossmatching', 'Blood Stains', 'Enzyme-Linked Immunosorbent Assay', 'Glycophorins', 'Humans', 'MNSs Blood-Group System'] | 12,536,417 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050'], ['E01.370.225.625.120', 'E01.370.225.812.385.120', 'E05.200.625.120', 'E05.200.812.385.120', 'E05.478.594.385.120'], ['I01.198.780.937.206'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170',... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Intraindividual comparison of psychophysical parameters between perimodiolar and lateral-type electrode arrays in patients with bilateral cochlear implants. | OBJECTIVE: Perimodiolar electrode arrays were developed to improve stimulation of specific neuronal populations and to decrease power consumption; however, they can damage the cochlear structure. We examined and compared psychophysical parameters of perimodiolar and lateral-type electrode arrays in patients who receive... | ['Acoustic Stimulation', 'Action Potentials', 'Adolescent', 'Child', 'Child, Preschool', 'Cochlear Implantation', 'Cochlear Implants', 'Evoked Potentials', 'Female', 'Hearing', 'Hearing Loss', 'Hearing Tests', 'Humans', 'Infant', 'Male', 'Retrospective Studies', 'Treatment Outcome'] | 25,473,955 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E04.580.450.220', 'E04.650.220'], ['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['G07.265.216.500', 'G11.561.200... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Meta-analysis of whole-brain radiotherapy plus temozolomide compared with whole-brain radiotherapy for the treatment of brain metastases from non-small-cell lung cancer. | The aim of this meta-analysis was to compare the efficiency of whole-brain radiotherapy (WBRT) plus temozolomide (TMZ) with WBRT for the treatment of brain metastases from non-small-cell lung cancer (NSCLC). For dichotomous variables, outcomes were reported as relative risk ratio (RR) and 95% confidence interval (CI) w... | ['Brain Neoplasms', 'Carcinoma, Non-Small-Cell Lung', 'Clinical Trials as Topic', 'Combined Modality Therapy', 'Cranial Irradiation', 'Humans', 'Lung Neoplasms', 'Publication Bias', 'Temozolomide', 'Treatment Outcome'] | 29,516,684 | [['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E02.186'], ['E02.815.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.8... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
SNPsyn: detection and exploration of SNP-SNP interactions. | SNPsyn (http://snpsyn.biolab.si) is an interactive software tool for the discovery of synergistic pairs of single nucleotide polymorphisms (SNPs) from large genome-wide case-control association studies (GWAS) data on complex diseases. Synergy among SNPs is estimated using an information-theoretic approach called intera... | ['Chromosome Mapping', 'Genome-Wide Association Study', 'Internet', 'Polymorphism, Single Nucleotide', 'Software'] | 21,576,219 | [['E05.393.183'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['L01.224.230.110.500'], ['G05.365.795.598'], ['L01.224.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Electrocardiographic left ventricular hypertrophy predicts recurrence of atrial arrhythmias after catheter ablation of paroxysmal atrial fibrillation. | BACKGROUND: Left ventricular hypertrophy (LVH) is an independent predictor of new-onset atrial fibrillation. Whether LVH can predict the recurrence of arrhythmia after radiofrequency catheter ablation (RFCA) in patients with paroxysmal atrial fibrillation (PAF) remains unclear.HYPOTHESIS: PAF patients with baseline-ele... | ['Aged', 'Anti-Arrhythmia Agents', 'Atrial Fibrillation', 'Catheter Ablation', 'Chi-Square Distribution', 'China', 'Disease-Free Survival', 'Echocardiography, Transesophageal', 'Electrocardiography', 'Female', 'Humans', 'Hypertrophy, Left Ventricular', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Multivariate Analy... | 29,604,089 | [['M01.060.116.100'], ['D27.505.954.411.097'], ['C14.280.067.198', 'C23.550.073.198'], ['E02.808.750.500', 'E04.014.760.500'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['Z01.252.474.164'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Lesional pulmonary edema]. | The authors having reported all the possible denominations of syndromes of respiratory distress in the adult mention again the main etiologies, stressing on the last ones. They recall afterwards the different clinical, radiological and biological stages of this syndrome. The hemodynamic profile is defined by normal cat... | ['Adult', 'Diagnosis, Differential', 'Hemodynamics', 'Humans', 'Lung', 'Oxygen', 'Positive-Pressure Respiration', 'Pulmonary Edema', 'Radiography', 'Respiration, Artificial', 'Respiratory Insufficiency'] | 370,812 | [['M01.060.116'], ['E01.171'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['D01.268.185.550', 'D01.362.670'], ['E02.041.625.790', 'E02.880.820.790'], ['C08.381.742'], ['E01.370.350.700'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820'], ['C08.618.846']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Thrombin peptide TP508 accelerates closure of dermal excisions in animal tissue with surgically induced ischemia. | TP508 is a synthetic peptide corresponding to amino acids 508 through 530 of human prothrombin. We previously demonstrated that a single topical application of TP508 stimulates revascularization and healing of acute incisional and excisional wounds in normal, healthy rat skin. To determine if TP508 would enhance wound ... | ['Animals', 'Dermatologic Surgical Procedures', 'Disease Models, Animal', 'Follow-Up Studies', 'Ischemia', 'Male', 'Peptide Fragments', 'Rats', 'Rats, Sprague-Dawley', 'Reference Values', 'Sensitivity and Specificity', 'Skin', 'Surgical Flaps', 'Treatment Outcome', 'Wound Healing'] | 11,208,179 | [['B01.050'], ['E04.680.275'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C23.550.513'], ['D12.644.541'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['E05.978.810'], ['E05.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Alpha-chains of IgM and IgD antigen receptor complexes are differentially N-glycosylated MB-1-related molecules. | The major B cell Ag receptors, membrane (m) IgM and mIgD, are noncovalently associated with disulfide-linked heterodimers of alpha, beta, and gamma glycoproteins. The beta and gamma chains have apparent molecular masses of 37 and 34 kDa, respectively, and are associated with both mIgM and mIgD. Receptor alpha chains, h... | ['Amino Acid Sequence', 'Animals', 'Antigens, CD', 'CD79 Antigens', 'Electrophoresis', 'Glycosylation', 'Immunoglobulin D', 'Immunoglobulin M', 'Membrane Glycoproteins', 'Mice', 'Molecular Sequence Data', 'Molecular Weight', 'Protein Processing, Post-Translational', 'Receptors, Antigen, B-Cell'] | 1,880,417 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D12.776.124.790.651.950.500', 'D12.776.377.715.548.950.500', 'D12.776.543.750.705.816.821.500'], ['E05.196.401', 'E05.301.300'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['D12.776.124.486.485.114.619.251', ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Usefulness of intracoronary brachytherapy for in-stent restenosis with a 188Re liquid-filled balloon. | The objective of this randomized pilot trial with 21 patients was to evaluate the effectiveness of a rhenium-188 liquid-filled balloon system to prevent recurrent restenosis after percutaneous transluminal coronary angioplasty for in-stent restenosis. A significant benefit from brachytherapy was seen at 6-month repeat ... | ['Aged', 'Angioplasty, Balloon', 'Brachytherapy', 'Coronary Angiography', 'Coronary Disease', 'Female', 'Humans', 'Male', 'Pilot Projects', 'Radioisotopes', 'Recurrence', 'Rhenium', 'Stents', 'Survival Analysis', 'Treatment Outcome'] | 11,179,537 | [['M01.060.116.100'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['E02.815.150'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250', 'C14.907.585.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Randomized controlled clinical trial comparing two dental implants with different neck configurations. | BACKGROUND: Peri-implant bone levels can vary according to the implant neck macro-design and the implant-abutment interface.PURPOSE: To compare the changes in soft and hard tissues when using a one-piece implant with a machined collar (TG) versus a two-piece implant with a progressive platform widening and a platform s... | ['Dental Implants', 'Dental Prosthesis Design', 'Female', 'Humans', 'Male', 'Middle Aged'] | 28,261,906 | [['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E06.780.346.625', 'E06.912.145'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Prognostic factors in patients with colorectal cancer at Hospital Universiti Sains Malaysia. | OBJECTIVE: To determine the 5-year survival rate and prognostic factors for survival in patients with colorectal cancer treated at the Surgical Unit, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia.METHODS: We retrospectively reviewed the records of 115 patients treated in HUSM from 1996 to 2005. Data of ... | ['Adolescent', 'Adult', 'Cohort Studies', 'Colorectal Neoplasms', 'Female', 'Hospitals, University', 'Humans', 'Malaysia', 'Male', 'Middle Aged', 'Prognosis', 'Retrospective Studies', 'Survival Rate', 'Young Adult'] | 21,163,410 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Interhemispheric endoscopic resection of large intraventricular and thalamic tumors. | A transfrontal route is the traditional endoscopic approach to intraventricular tumors. Small lesions can be biopsied using the parallel port channel of the endoscope. For larger tumors a ventriculoport can be used for resection. This technique nevertheless requires traversing the brain tissue, is difficult in the sett... | ['Cerebral Ventricle Neoplasms', 'Cerebral Ventricles', 'Child', 'Endoscopy', 'Humans', 'Magnetic Resonance Imaging', 'Neurosurgical Procedures', 'Postoperative Complications', 'Surgical Instruments', 'Thalamic Diseases', 'Thalamus', 'Treatment Outcome'] | 21,631,194 | [['C04.588.614.250.195.205', 'C10.228.140.211.280', 'C10.551.240.250.200'], ['A08.186.211.140'], ['M01.060.406'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E04.525'], ['C23.550.767'], ['E07.858.700'], ['C10.228.140.915'], ['A08.186.211.200.317.826'],... | ['Diseases [C]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A comparative study of preparations of ovine lutenizing hormone by bioassay, immunodoublediffusion, radioimmunoassay, radioreceptor assay and polyacrylamide gel electrophoresis. | Three preparations of ovine LH were compared for biological potency and by several in vitro parameters. All were found to be heterogenous by immunodoublediffusion and by electrophoresis in polyacrylamide gels. They all also showed similarities and/or differences with respect to their characteristics in immunodoublediff... | ['Animals', 'Biological Assay', 'Electrophoresis, Polyacrylamide Gel', 'Immunodiffusion', 'Luteinizing Hormone', 'Radioimmunoassay', 'Radioligand Assay', 'Sheep'] | 813,473 | [['B01.050'], ['E05.091'], ['E05.196.401.402', 'E05.301.300.319'], ['E01.370.225.812.735.645.350', 'E05.200.812.735.645.350', 'E05.478.594.760.645.350', 'E05.478.605.492.350'], ['D06.472.699.322.576.463', 'D06.472.699.631.525.343.463', 'D12.644.548.691.525.343.463'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elimination of Cigarette Smoke-derived Acetaldehyde in Saliva by Slow-release L-Cysteine Lozenge Is a Potential New Method to Assist Smoking Cessation. A Randomised, Double-blind, Placebo-controlled Intervention. | BACKGROUND/AIM: Harmans are condensation products of acetaldehyde and biogenic amines in saliva. Like other monoamine oxidase inhibitors, harmans help maintain behavioral sensitization to nicotine and mediate the addictive potential of cigarette smoke-derived acetaldehyde. The aim of this study was to test the hypothes... | ['Acetaldehyde', 'Administration, Oral', 'Adult', 'Breath Tests', 'Carbon Monoxide', 'Cysteine', 'Delayed-Action Preparations', 'Double-Blind Method', 'Female', 'Follow-Up Studies', 'Harmine', 'Humans', 'Male', 'Medical Records', 'Middle Aged', 'Saliva', 'Smoke', 'Smoking Cessation', 'Surveys and Questionnaires', 'Toba... | 27,127,136 | [['D02.047.064'], ['E02.319.267.100'], ['M01.060.116'], ['E01.370.100'], ['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D26.255.210', 'E02.319.300.253'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Surgical treatment of developmental dysplasia of the hip presenting in children above 10 years. | BACKGROUND: Management of developmental dysplasia of the hip in older children remains controversial. The objective of this study was to evaluate the results of surgical treatment of developmental dysplasia of the hip in children older than 10 years.METHOD: Sixty-three patients (75 hips) whose mean age at the time of s... | ['Adolescent', 'Age Factors', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Hip Dislocation, Congenital', 'Hip Joint', 'Humans', 'Male', 'Osteotomy', 'Range of Motion, Articular', 'Retrospective Studies', 'Severity of Illness Index', 'Tomography, X-Ray Computed', 'Treatment Outcome', 'Young Adult'] | 21,327,979 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C05.660.297.500', 'C16.131.621.297.500', 'C16.131.621.449'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The influence of intermittent hypoxemia on platelet activation in obese patients with obstructive sleep apnea. | OBJECTIVES: Literature regarding platelet function in obstructive sleep apnea (OSA) has considerable limitations. Given the central role of platelets in atherothrombosis and the known cardiovascular risk of OSA, we hypothesized that OSA severity is predictive of platelet function, independent of known comorbidities.DES... | ['Adolescent', 'Adult', 'Aged', 'Biomarkers', 'Body Mass Index', 'Chi-Square Distribution', 'Female', 'Flow Cytometry', 'Humans', 'Hypoxia', 'Male', 'Obesity', 'Platelet Activation', 'Polysomnography', 'Sleep Apnea, Obstructive', 'Statistics, Nonparametric', 'Young Adult'] | 21,509,332 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D23.101'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Geographic distribution of human T-lymphotropic virus types 1 and 2 among mothers of newborns tested during neonatal screening, Minas Gerais, Brazil. | OBJECTIVE: To evaluate the geographic distribution of human T-lymphotropic virus types 1 and 2 (HTLV-1/2) in the State of Minas Gerais, Brazil, in puerperal women whose newborns were tested for HTLV-1/2 during neonatal screening, and to overlap seropositivity with social and economic status determinants.METHODS: During... | ['Adult', 'Brazil', 'Carrier State', 'Female', 'HTLV-I Antibodies', 'HTLV-I Infections', 'HTLV-II Antibodies', 'HTLV-II Infections', 'Human T-lymphotropic virus 1', 'Human T-lymphotropic virus 2', 'Humans', 'Infant, Newborn', 'Infectious Disease Transmission, Vertical', 'Neonatal Screening', 'Postpartum Period', 'Preva... | 20,602,066 | [['M01.060.116'], ['Z01.107.757.176'], ['N06.850.520.169'], ['D12.776.124.486.485.114.254.150.500', 'D12.776.124.790.651.114.254.150.500', 'D12.776.377.715.548.114.254.150.500'], ['C01.925.782.815.200.470', 'C20.673.483.470'], ['D12.776.124.486.485.114.254.150.510', 'D12.776.124.790.651.114.254.150.510', 'D12.776.377.7... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Serum FSH levels in women with polycystic ovary syndrome during ovulation induction using down-regulation and urofollitropin. | OBJECTIVE: To evaluate retrospectively the use of serum FSH levels and to correlate them with follicular growth in a clinical ovulation induction program.METHODS: Twenty women with infertility due to anovulation associated with polycystic ovary syndrome (PCOS) were studied. The patients were down-regulated with a long ... | ['Adult', 'Buserelin', 'Embryo Transfer', 'Female', 'Fertilization in Vitro', 'Follicle Stimulating Hormone', 'Humans', 'Infertility, Female', 'Obesity', 'Ovulation', 'Ovulation Induction', 'Polycystic Ovary Syndrome', 'Pregnancy', 'Pregnancy Rate', 'Retrospective Studies'] | 9,186,269 | [['M01.060.116'], ['D06.472.699.327.740.320.100', 'D12.644.400.400.740.320.100', 'D12.644.456.460.150', 'D12.644.548.365.740.320.100', 'D12.776.631.650.405.740.320.100'], ['E02.875.800.500', 'E05.820.800.500'], ['E02.875.800.750', 'E05.820.800.750'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Locking plate osteosynthesis for fractures of the proximal humerus]. | BACKGROUND: Beside non-operative treatment the therapeutic options for proximal fractures of the humerus range from closed reduction and transcutaneous K-wiring to total joint replacement. While the first is regarded as minimally invasive the latter is a rather complex intervention. Plating has been disregarded as comb... | ['Aged', 'Bone Plates', 'Bone Wires', 'Equipment Design', 'Female', 'Follow-Up Studies', 'Fracture Fixation, Internal', 'Humans', 'Male', 'Middle Aged', 'Outcome and Process Assessment, Health Care', 'Postoperative Complications', 'Radiography', 'Shoulder Fractures'] | 12,594,610 | [['M01.060.116.100'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['E07.695.370.468', 'E07.858.442.660.460.468', 'E07.858.690.725.460.468'], ['E05.320'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.555.300.300'], ['B01.050.150.900.649.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Interactive effects of age, sex, and strain on apparent ileal amino acid digestibility of soybean meal and an animal by-product blend in broilers. | The objectives of this study were to determine if age, sex, and strain of broilers affect the apparent ileal amino acid digestibility (AID) of soybean meal and an animal by-product blend. Chicks from 2 broiler strains, 1 commercially available and the other in the test phase, were obtained from a common hatchery, feath... | ['Aging', 'Amino Acids', 'Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Chickens', 'Diet', 'Dietary Proteins', 'Dietary Supplements', 'Digestion', 'Female', 'Ileum', 'Male', 'Random Allocation', 'Sex Distribution', 'Soybeans'] | 22,399,730 | [['G07.345.124'], ['D12.125'], ['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G07.203.650.240'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.300.456', 'J02.500.456'], ['G07.203.650.250', 'G10.261.190'], ['A... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
Hysteria, or "suffocation of the mother". | OBJECTIVE: To understand or explain the surprising adherence of prominent physicians throughout the centuries to terms suggesting that the womb could move and cause suffocation, choking or difficulty in swallowing.DATA SOURCES: Hippocratic writings on hysterical symptoms and the views of subsequent authors and contexts... | ['Anxiety', 'Female', 'History, 17th Century', 'History, 18th Century', 'History, 19th Century', 'History, Ancient', 'History, Medieval', 'Humans', 'Hysteria', 'Mothers', 'Uterine Diseases'] | 8,439,911 | [['F01.470.132'], ['K01.400.504.750'], ['K01.400.504.875'], ['K01.400.504.937'], ['K01.400.470'], ['K01.400.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.675.400.500'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630'], ['C13.351.500.852']] | ['Psychiatry and Psychology [F]', 'Humanities [K]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Toward an understanding of mothering: the care giving process of mothers with autistic children. | The purpose of this study was to explore the care-giving experience of mothers with autistic children. In this qualitative study, a focus group and in-depth interviews were conducted with mothers with an autistic child to uncover the nature of their mothering experience. Data were analyzed for themes with the constant ... | ['Autistic Disorder', 'Caregivers', 'Child', 'Disabled Children', 'Female', 'Humans', 'Maternal Behavior', 'Mothers'] | 11,779,092 | [['F03.625.164.113.500'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['M01.060.406'], ['M01.150.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.370.215'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A randomized controlled trial comparing three single-incision minislings for stress urinary incontinence. | INTRODUCTION AND HYPOTHESIS: Studies have observed a significant heterogeneity in efficacy data for single-incision minislings (SIMS) as surgical treatment for female urinary incontinence (UI). Our study aim was to test the hypothesis that different vaginal kits for SIMS have different long-term outcomes.METHODS: One h... | ['Aged', 'Equipment Design', 'Female', 'Follow-Up Studies', 'Humans', 'Middle Aged', 'Quality of Life', 'Sexual Behavior', 'Suburethral Slings', 'Time Factors', 'Treatment Outcome', 'Urinary Incontinence, Stress'] | 24,737,301 | [['M01.060.116.100'], ['E05.320'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['F01.145.802'], ['E07.695.752'], ['G01.910.857'], ['E01.789.800'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Delayed closure of open abdomen in septic patients treated with negative pressure wound therapy and dynamic fascial suture: the long-term follow-up study. | INTRODUCTION: Negative pressure wound therapy (NPWT) is widely used in the treatment of open abdomen (OA). The use of dynamic fascial sutures (DFS) increases the rate of successful delayed closure by reducing fascial lateralization. We recently published a prospective controlled trial including 87 patients undergoing a... | ['Abdominal Wound Closure Techniques', 'Adult', 'Aged', 'Aged, 80 and over', 'Fascia', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Negative-Pressure Wound Therapy', 'Peritonitis', 'Postoperative Complications', 'Prospective Studies', 'Surgical Mesh', 'Surveys and Questionnaires', 'Sutures'] | 28,424,908 | [['E04.987.100'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A02.340', 'A10.165.425'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.309.610', 'E04.237.444', 'E04.987.550'], ['C... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Structure and reactivity of the cysteine methyl ester radical cation. | The structure and reactivity of the cysteine methyl ester radical cation, CysOMe(.+) , have been examined in the gas phase using a combination of experiment and density functional theory (DFT) calculations. CysOMe(.+) undergoes rapid ion-molecule reactions with dimethyl disulfide, allyl bromide, and allyl iodide, but i... | ['Cations', 'Computer Simulation', 'Cysteine', 'Gases', 'Isomerism', 'Kinetics', 'Molecular Structure', 'Spectrophotometry, Infrared', 'Tandem Mass Spectrometry', 'Thermodynamics'] | 21,226,102 | [['D01.248.497.300'], ['L01.224.160'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D01.362'], ['G02.111.570.685', 'G02.607.445'], ['G01.374.661', 'G02.111.490'], ['G02.111.570', 'G02.466'], ['E05.196.712.726.676', 'E05.196.867.826.676'], ['E05.196.566.880'], ['G01.906']] | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The magnitude of left ventricular myocardial hypertrophy related to the degree of its dysfunction in patients with dilated cardiomyopathy (DCM). | The aim of the study was to analyze the relationship between the magnitude of left ventricular (LV) hypertrophy and selected haemodynamic parameters reflecting LV systolic and diastolic function. The "hypertrophy-function" relationship was evaluated in 22 patients with dilated cardiomyopathy (DCM) and in patients with ... | ['Adolescent', 'Adult', 'Aortic Valve Insufficiency', 'Cardiomyopathy, Dilated', 'Female', 'Heart Failure', 'Hemodynamics', 'Humans', 'Hypertrophy, Left Ventricular', 'Male', 'Middle Aged', 'Mitral Valve Insufficiency', 'Ventricular Function, Left'] | 1,306,417 | [['M01.060.057'], ['M01.060.116'], ['C14.280.484.048.500'], ['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['C14.280.434'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.195.400', 'C23.300.775.250.400'], ['M01.060.116.630'], ['C14.280.484.461'], ['G09.330.955.800']] | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparative study of plasma ghrelin levels in women with polycystic ovary syndrome, in hyperandrogenic women and in normal controls. | BACKGROUND: Ghrelin is a novel peptide associated with energy balance, obesity, and perhaps gonadal function. The present study was designed in order: (i) to compare plasma ghrelin levels between women with PCOS, women who presented only with hyperandrogenaemia and healthy controls; and (ii) to investigate the relation... | ['17-alpha-Hydroxyprogesterone', 'Adolescent', 'Adult', 'Androstenedione', 'Dehydroepiandrosterone Sulfate', 'Female', 'Follicle Stimulating Hormone', 'Ghrelin', 'Humans', 'Hyperandrogenism', 'Luteinizing Hormone', 'Peptide Hormones', 'Polycystic Ovary Syndrome', 'Sex Hormone-Binding Globulin', 'Testosterone'] | 15,890,737 | [['D04.210.500.745.745.654.829.395.400', 'D06.472.334.851.687.750.478.400'], ['M01.060.057'], ['M01.060.116'], ['D04.210.500.054.079.329', 'D04.210.500.578.502.112', 'D06.472.040.502.112', 'D06.472.334.851.968.875'], ['D04.210.500.054.079.429.625.300', 'D04.210.500.578.502.400.300', 'D06.472.040.502.400.300', 'D06.472.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Frequency distribution of autoimmunity associated FCGR3B gene copy number in Indian population. | Amongst several human genome variations, copy number variations (CNVs) are considered as an important source of variability contributing to susceptibility to wide range of diseases. Although CNV is scattered for genes throughout the human genome, several of autoimmunity related genes have CN variation and therefore pla... | ['Arthritis, Rheumatoid', 'Autoimmunity', 'DNA Copy Number Variations', 'Diabetes Mellitus, Type 1', 'GPI-Linked Proteins', 'Gene Dosage', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Humans', 'India', 'Lupus Erythematosus, Systemic', 'Receptors, IgG'] | 25,428,402 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['G12.450.192'], ['G05.365.795.297.500'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['D12.776.395.550.448', 'D12.776.543.484.500', 'D12.776.543.550.418'], ['G05.380.350'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.1... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
A novel gene selectively expressed in the cerebellum. | A cDNA clone encoding a novel protein (Cer-1) was isolated from a mouse cerebellar cDNA library. The deduced amino acid sequence of Cer-1 is not homologous to other sequences in the protein sequence data base. RNA blot analysis suggests that expression of Cer-1 RNA occurs selectively in the adult cerebellum and in puri... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cerebellum', 'Gene Expression', 'Mice', 'Mice, Inbred Strains', 'Molecular Sequence Data', 'RNA', 'Tissue Distribution'] | 8,761,990 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A08.186.211.132.810.428.200'], ['G05.297'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ['L01.453.245.667'], ['D13.444.735']... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Immediate-Type allergy against human insulin associated with marked eosinophilia in type 2 diabetic patient. | We describe a type 2 diabetic patient who showed immediate-type allergy against human insulin associated with marked eosinophilia at initial insulin therapy. Three months after initiation of insulin therapy, he noticed itchy skin wheals at the site of the insulin injection. Laboratory data at that time showed marked eo... | ['Aged', 'Aged, 80 and over', 'Cyclohexanes', 'Diabetes Mellitus, Type 2', 'Drug Hypersensitivity', 'Eosinophilia', 'Erythema', 'Humans', 'Hypersensitivity, Immediate', 'Hypoglycemic Agents', 'Immunoglobulin E', 'Insulin', 'Male', 'Nateglinide', 'Phenylalanine', 'Seasons', 'Skin Tests'] | 11,523,901 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D02.455.426.392.368.367'], ['C18.452.394.750.149', 'C19.246.300'], ['C20.543.206', 'C25.100.468'], ['C15.378.553.231'], ['C17.800.229', 'C23.888.885.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543.480'], ['D27.505.696.422'], ['D12.776.124.486.485.114.61... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gastrointestinal and nutritional sequelae of bone marrow transplantation. | The nature of the gastrointestinal injury following bone marrow transplantation and its clinical and nutritional sequelae are poorly defined. Prospective assessments of gastrointestinal function, nutritional status, and wellbeing were therefore carried out in 47 consecutive patients (28 males, 19 females; mean age 8.4 ... | ['Bone Marrow Transplantation', 'Celiac Disease', 'Child', 'Diarrhea', 'Exocrine Pancreatic Insufficiency', 'Female', 'Gastrointestinal Diseases', 'Graft vs Host Disease', 'Humans', 'Male', 'Nutritional Status', 'Parenteral Nutrition', 'Prospective Studies', 'Protein-Losing Enteropathies', 'Serum Albumin'] | 8,976,659 | [['E02.095.147.725.040', 'E04.936.580.040'], ['C06.405.469.637.250', 'C18.452.603.250'], ['M01.060.406'], ['C23.888.821.214'], ['C06.689.276'], ['C06.405'], ['C20.452'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.650.650', 'N01.224.425.525'], ['E02.421.505', 'E02.642.500.505'], ['E05.318.372.500.750.625... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Contracting and monitoring relationships for adolescents with type 1 diabetes: a pilot study. | BACKGROUND: Adolescents are developmentally in a period of transition-from children cared for by their parents to young adults capable of self-care, independent judgment, and self-directed problem solving. We wished to develop a behavioral contract for adolescent diabetes management that addresses some negotiable point... | ['Adolescent', 'Adolescent Behavior', 'Blood Glucose Self-Monitoring', 'Caregivers', 'Cell Phone', 'Diabetes Mellitus, Type 1', 'Family Conflict', 'Female', 'Glycated Hemoglobin A', 'Goals', 'Health Behavior', 'Humans', 'Indiana', 'Male', 'Negotiating', 'Parent-Child Relations', 'Patient Compliance', 'Pilot Projects', ... | 21,406,011 | [['M01.060.057'], ['F01.145.022'], ['E01.370.225.124.100.105', 'E01.370.374.100', 'E01.370.520.100', 'E02.900.950.500', 'E05.200.124.100.105'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['L01.178.847.698.300'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['F01.829.263.370.054', 'F01.829.401.142'], ['D09... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Hu... | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Outcomes after viral load rebound on first-line antiretroviraltreatment in children with HIV in the UK and Ireland: an observational cohort study. | BACKGROUND: About a third of children with HIV have virological failure within 2 years of beginning antiretroviral treatment (ART). We assessed the probability of switch to second-line ART or virological re-suppression without switch in children who had virological rebound on first-line ART in the UK and Ireland.METHOD... | ['Adolescent', 'Anti-HIV Agents', 'Antiretroviral Therapy, Highly Active', 'CD4 Lymphocyte Count', 'Child', 'Child, Preschool', 'Disease Progression', 'Drug Administration Schedule', 'England', 'Female', 'HIV Infections', 'Humans', 'Ireland', 'Male', 'Practice Guidelines as Topic', 'Reverse Transcriptase Inhibitors', '... | 26,413,561 | [['M01.060.057'], ['D27.505.954.122.388.077.088'], ['E02.319.310.075'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500.150', 'G04.140.107.595.500.150', 'G09.188.105.595.500.150'], ['M01.060.406'], ['M0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cables enhances cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers. | Cyclin-dependent kinase 2 (cdk2) is a small serine/threonine kinase that regulates cell cycle progression. Cdk2 activity is tightly controlled by several mechanisms, including phosphorylation and dephosphorylation events. Cables is a recently described novel cdk-interacting protein. In proliferating cells, Cables was p... | ['Animals', 'CDC2-CDC28 Kinases', 'COS Cells', 'Carcinoma, Squamous Cell', 'Carrier Proteins', 'Cell Cycle Proteins', 'Chromosomes, Human, Pair 18', 'Colonic Neoplasms', 'Cyclin-Dependent Kinase 2', 'Cyclin-Dependent Kinases', 'Cyclins', 'DNA, Complementary', 'Growth Inhibitors', 'HeLa Cells', 'Head and Neck Neoplasms'... | 11,585,773 | [['B01.050'], ['D08.811.913.696.620.682.700.646.500.500', 'D12.644.360.250.067', 'D12.776.167.200.067', 'D12.776.476.250.067'], ['A11.251.210.172.500', 'A11.329.228.220'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D12.776.157'], ['D12.776.167'], ['A11.284.187.520.300.415.430', 'G05.360.162.520.300.415.430'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tibolone in postmenopausal women with systemic lupus erythematosus: a pilot study. | OBJECTIVE: To determine the influence of the use of tibolone on the frequency of flares of systemic lupus erythematosus (SLE) in postmenopausal patients.METHODS: Thirty patients with inactive or controlled SLE were included in the study. Patients were randomized to receive a 12-month course of either tibolona (2.5 mg/d... | ['Cholesterol, HDL', 'Double-Blind Method', 'Estrogen Receptor Modulators', 'Estrogen Replacement Therapy', 'Estrogens', 'Female', 'Humans', 'Lupus Erythematosus, Systemic', 'Middle Aged', 'Norpregnenes', 'Pilot Projects', 'Postmenopause', 'Severity of Illness Index', 'Treatment Outcome', 'Triglycerides'] | 19,193,505 | [['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D06.347.360', 'D27.505.696.399.450.360'], ['E02.319.452.150'], ['D27.505.696.399.472.277'], ['B01.050.150.900.649.313.988.400.112.400... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ribosomal protein S4 is an internal protein: Localization by immunoelectron microscopy on protein-deficient subribosomal particles. | The location of protein S4 in the small ribosomal subunit has been identified by immunoelectron microscopy. Although intact small subunits are not reactive with antibodies directed against protein S4, subribosomal particles reconstituted without proteins S5 and S12 are reactive. By using these "incomplete" subparticles... | ['Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Immune Sera', 'Immunoassay', 'Microscopy, Electron', 'Models, Structural', 'Molecular Weight', 'Ribosomal Proteins', 'Ribosomes'] | 6,752,941 | [['E05.196.401.402', 'E05.301.300.319'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.114.573', 'D20.215.401'], ['E05.478.566', 'E05.601.470'], ['E01.370.350.515.402', 'E05.595.402'], ['J01.897.280.500.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
"Stuck in the middle with you": the ethics and process of qualitative research with two people in an intimate relationship. | In this article, the authors discuss their experiences of two separate research projects involving interviews with both partners in care relationships that pushed the ethics of research methods along unfamiliar routes. The desire to understand the relationship from both sides was seen to outweigh the perils of accessin... | ['Caregivers', 'Ethics, Research', 'Female', 'Humans', 'Interpersonal Relations', 'Interviews as Topic', 'Male', 'Marriage', 'Mental Health', 'Qualitative Research', 'Researcher-Subject Relations'] | 14,658,357 | [['M01.085', 'M01.526.485.200', 'N02.360.200'], ['K01.752.566.479.173', 'N05.350.670'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['F01.829.263.315.500.500', 'I01.240.361.500.500', 'I01.880.853.150.423.500.500'... | ['Named Groups [M]', 'Health Care [N]', 'Humanities [K]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Consistency of adherence across regimen demands. | The extent to which adherence to one demand of the diabetic treatment regimen is related to adherence to other regimen demands was explored in a sample of 227 diabetic patients. Adherence to weight control, urine/blood testing, medication taking, symptom reporting, and safety demands was assessed using a variety of met... | ['Adult', 'Combined Modality Therapy', 'Diabetes Mellitus, Type 1', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Male', 'Middle Aged', 'Patient Compliance', 'Sick Role'] | 2,707,222 | [['M01.060.116'], ['E02.186'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['F01.829.316.616.751']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hospital outbreak of multi-resistant Acinetobacter anitratus: an airborne mode of spread? | During a 10-month period, from October 1984 to July 1985, a multi-resistant strain of Acinetobacter anitratus was isolated from 36 patients in three neurosurgical wards, one medical ward and the intensive care unit of a district general hospital, and from two patients in the intensive care unit of a hospital in another... | ['Acinetobacter', 'Acinetobacter Infections', 'Adolescent', 'Adult', 'Aged', 'Air Microbiology', 'Antisepsis', 'Bacteriological Techniques', 'Cross Infection', 'Disease Outbreaks', 'England', 'Female', 'Humans', 'Male', 'Microbial Sensitivity Tests', 'Middle Aged', 'Skin'] | 2,883,217 | [['B03.440.400.425.537.050', 'B03.660.250.530.050'], ['C01.150.252.400.560.022'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['H01.158.273.540.274.110', 'N06.850.425.110'], ['N06.850.780.200.450.150'], ['E01.370.225.875.150', 'E05.200.875.150'], ['C01.248', 'C23.550.291.875.500'], ['N06.850.290'], ['Z01.542... | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
BF-30 effectively inhibits ciprofloxacin-resistant bacteria in vitro and in a rat model of vaginosis. | Bacterial infections are becoming increasingly difficult to treat due to the increasing number of multidrug-resistant strains. Cathelicidin-BF (BF-30) is a cathelicidin-like antimicrobial peptide and exhibits broad antimicrobial activity against bacteria. In the present study, the antibacterial activity of BF-30 agains... | ['Animals', 'Cathelicidins', 'Ciprofloxacin', 'Disease Models, Animal', 'Drug Resistance, Bacterial', 'Escherichia coli', 'Female', 'Rats', 'Staphylococcus aureus', 'Treatment Outcome', 'Vaginosis, Bacterial'] | 24,114,557 | [['B01.050'], ['D12.644.050.099', 'D12.776.543.695.054.099'], ['D03.633.100.810.835.322.186'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.992.635.505.700'], ['B03.300.390.400.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Endovascular Management of Ruptured Distal Anterior Cerebral Artery (DACA) Aneurysms: A Retrospective Review Study. | OBJECTIVE: Distal anterior cerebral artery (DACA) aneurysms are rare, and their treatment by either surgical clipping or endovascular treatment poses technical difficulties. Earlier studies have reported higher complication rates in DACA aneurysms compared with other aneurysms in the circle of Willis. Therefore, endova... | ['Adult', 'Aged', 'Aneurysm, Ruptured', 'Cerebral Angiography', 'Embolization, Therapeutic', 'Endovascular Procedures', 'Female', 'Humans', 'Intracranial Aneurysm', 'Male', 'Middle Aged', 'Retrospective Studies', 'Subarachnoid Hemorrhage', 'Treatment Outcome'] | 28,823,655 | [['M01.060.116'], ['M01.060.116.100'], ['C14.907.055.185'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['E02.520.360', 'E02.926.500'], ['E04.100.814.529', 'E04.502.382'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Exploring multiple binding sites of an indoloquinoline in triple-helical DNA: a paradigm for DNA triplex-selective intercalators. | Employing NMR spectroscopic methods preferred binding sites of a triplex-selective indoloquinoline drug were examined with three DNA triplex targets. To directly derive and evaluate number and type of the different sites of interaction, studies were performed on short triple-helical constructs specifically labeled with... | ['Binding Sites', 'DNA', 'Indoles', 'Intercalating Agents', 'Ligands', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Nucleic Acid Conformation', 'Oligonucleotides', 'Protons', 'Quinolines'] | 25,281,796 | [['G02.111.570.120'], ['D13.444.308'], ['D03.633.100.473'], ['D27.720.470.410.360'], ['D27.720.470.480'], ['E05.196.867.519'], ['E05.599.595'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.695.578.424'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['D03.633.100.810']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The first archaeal L-aspartate dehydrogenase from the hyperthermophile Archaeoglobus fulgidus: gene cloning and enzymological characterization. | A gene encoding an L-aspartate dehydrogenase (EC 1.4.1.21) homologue was identified in the anaerobic hyperthermophilic archaeon Archaeoglobus fulgidus. After expression in Escherichia coli, the gene product was purified to homogeneity, yielding a homodimeric protein with a molecular mass of about 48 kDa. Characterizati... | ['Amino Acid Oxidoreductases', 'Amino Acid Sequence', 'Archaeoglobus fulgidus', 'Cloning, Molecular', 'Dimerization', 'Enzyme Stability', 'Escherichia coli', 'Kinetics', 'Molecular Sequence Data', 'Oxaloacetic Acid', 'Protein Structure, Tertiary', 'Sequence Homology, Amino Acid'] | 16,731,057 | [['D08.811.682.664.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B02.200.080.080.100'], ['E05.393.220'], ['G02.206', 'G03.230'], ['E05.916.360', 'G02.111.700.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.374.661', 'G02.111.490'], ['L01.453.245.667'], ['D02.241.081.337.593.812.750', 'D02.24... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Quantitative characterization of the relief of body surface potential distribution. | The body surface distribution of the cardiac electric field is best represented as reliefs of positive and negative potentials, or their time integrals. The objective of this study was to design a methodology of their quantitative evaluation. QRST isointegral maps were obtained from 45 healthy subjects (35 men, 10 wome... | ['Adolescent', 'Adult', 'Aged', 'Body Surface Potential Mapping', 'Child', 'Child, Preschool', 'Female', 'Fuzzy Logic', 'Humans', 'Male', 'Middle Aged', 'Signal Processing, Computer-Assisted'] | 11,763,677 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.370.380.240.850.100', 'E01.370.405.240.850.100'], ['M01.060.406'], ['M01.060.406.448'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['L01.224.800']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Response to thermal stress and personality. | Tolerance to cold and heat exposure shows large variations for which there is still insufficient explanation. On the other hand the relationship between the responses to mental stress and individual personality is well documented. The aim of this study was then to find if personality traits have some influence on the r... | ['Adaptation, Physiological', 'Adaptation, Psychological', 'Adult', 'Extraversion, Psychological', 'Female', 'Humans', 'Male', 'Neurotic Disorders', 'Oxygen Consumption', 'Personality', 'Personality Assessment', 'Stress, Physiological', 'Temperature'] | 14,568,309 | [['G07.025', 'G16.012.500'], ['F01.058'], ['M01.060.116'], ['F01.752.747.246', 'F02.739.794.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.080.550', 'F03.650'], ['G03.680'], ['F01.752'], ['F04.513'], ['G07.775'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.23... | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mobilizing Education to Nurses at the Bedside. | After a survey revealed practice gaps in central venous catheter care, one organization was challenged to identify a novel approach to educate nurses. Through a search for evidence, a project workgroup discovered an existing but beneficial teaching method, using a mobile cart to deliver meaningful education at the poin... | ['Catheter-Related Infections', 'Catheterization, Central Venous', 'Clinical Competence', 'Humans', 'Inservice Training', 'Nursing Staff, Hospital', 'Teaching Materials'] | 31,022,091 | [['C01.195'], ['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['M01.526.485.680.490', 'M01.526.485.740.523', 'N02.360.680.490', 'N02.360.740.523'], ['L01.178.820']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Diagnostic Thyroidectomy May Be Preferable in Patients With Suspicious Ultrasonography Features After Cytopathology Diagnosis of AUS/FLUS in the Bethesda System. | Atypia/follicular lesion of undetermined significance (AUS/FLUS) is a new category in the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) for which repeat fine-needle aspiration cytology (FNAC) is recommended. The aim of this study was to identify specific ultrasonography and clinical predictors of malignan... | ['Biopsy, Fine-Needle', 'Calcinosis', 'Humans', 'Retrospective Studies', 'Thyroid Neoplasms', 'Thyroid Nodule', 'Thyroidectomy', 'Ultrasonography, Interventional'] | 26,705,204 | [['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['C18.452.174.130'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Intrahepatic biliary strictures after liver transplantation. | PURPOSE: To evaluate the prevalence, cholangiographic features, causes, and management of intrahepatic biliary strictures in hepatic transplants.MATERIALS AND METHODS: Over a 12-year period, cholangiography was performed in 1,590 liver allografts. Confirmed cases of stricture were evaluated and correlated with clinical... | ['Adolescent', 'Adult', 'Aged', 'Bile Ducts, Intrahepatic', 'Child', 'Child, Preschool', 'Constriction, Pathologic', 'Female', 'Humans', 'Infant', 'Liver Transplantation', 'Male', 'Middle Aged', 'Postoperative Care', 'Radiography', 'Retrospective Studies'] | 8,184,054 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A03.159.183.158', 'A03.620.150'], ['M01.060.406'], ['M01.060.406.448'], ['C23.300.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['M01.060.116.630'], ['E02.76... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Centrifugal partition extraction in the pH-zone-refining displacement mode: an efficient strategy for the screening and isolation of biologically active phenolic compounds. | Centrifugal partition extraction (CPE) was developed for the first time in the pH-zone-refining mode to fractionate a crude bark extract of the African tree Anogeissus leiocarpus Guill. & Perr. (Combretaceae). The fractionation process was performed at a flow rate of 20mL/min using a biphasic solvent system composed of... | ['Antioxidants', 'Biphenyl Compounds', 'Centrifugation', 'Chromatography, Liquid', 'Combretaceae', 'Ellagic Acid', 'Flavonoids', 'Hydrogen-Ion Concentration', 'Nuclear Magnetic Resonance, Biomolecular', 'Phenols', 'Picrates', 'Plant Bark', 'Plant Extracts', 'Triterpenes'] | 24,008,119 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.455.426.559.389.185'], ['E05.181'], ['E05.196.181.400'], ['B01.650.940.800.575.912.250.228'], ['D03.383.663.283.500', 'D03.633.100.150.500'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['G02.300'], ['E05.196.867.519.550'], ['D02.455.426.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficient and biologically relevant consensus strategy for Parkinson's disease gene prioritization. | BACKGROUND: The systemic information enclosed in microarray data encodes relevant clues to overcome the poorly understood combination of genetic and environmental factors in Parkinson's disease (PD), which represents the major obstacle to understand its pathogenesis and to develop disease-modifying therapeutics. While ... | ['Algorithms', 'Case-Control Studies', 'Gene Expression Regulation', 'Gene Ontology', 'Gene Regulatory Networks', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Humans', 'Machine Learning', 'Oligonucleotide Array Sequence Analysis', 'Parkinson Disease', 'Reproducibility of Results'] | 26,961,748 | [['G17.035', 'L01.224.050'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G05.308'], ['H01.158.273.343.249.099', 'H01.770.644.145.350.124', 'L01.224.050.375.480.500.500', 'L01.313.500.750.300.550.500.500', 'L01.453.245.945.079.500'], ['G05.360.080.689.360'], ['E05.393.385'], ['C23.55... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Differences in histological features and PD-L1 expression between sporadic microsatellite instability and Lynch-syndrome-associated disease in Japanese patients with colorectal cancer. | BACKGROUND: The field of immunotherapy has recently focused on cancers with microsatellite instability (MSI). These cancers include both Lynch-syndrome-associated tumors, which are caused by mismatch repair (MMR) germline mutations, and sporadic MSI tumors, which are mainly attributed to MLH1 promoter methylation. The ... | ['Adult', 'Aged', 'Asian Continental Ancestry Group', 'B7-H1 Antigen', 'Colorectal Neoplasms', 'Colorectal Neoplasms, Hereditary Nonpolyposis', 'DNA Methylation', 'Female', 'Humans', 'Male', 'Microsatellite Instability', 'Middle Aged', 'MutL Protein Homolog 1', 'Mutation', 'Promoter Regions, Genetic', 'Proto-Oncogene P... | 29,327,160 | [['M01.060.116'], ['M01.060.116.100'], ['M01.686.508.200'], ['D12.776.465.625', 'D12.776.467.150.300', 'D12.776.543.095.300', 'D23.050.301.285.400', 'D23.529.168.300'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['C04.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adult presentation of Bartter syndrome type IV with erythrocytosis. | Bartter syndrome comprises a group of rare autosomal-recessive salt-losing disorders with distinct phenotypes, but one unifying pathophysiology consisting of severe reductions of sodium reabsorption caused by mutations in five genes expressed in the thick ascending limb of Henle, coupled with increased urinary excretio... | ['Alkalosis', 'Bartter Syndrome', 'Brazil', 'Chloride Channels', 'Deafness', 'Humans', 'Hyperparathyroidism, Secondary', 'Hypokalemia', 'Late Onset Disorders', 'Male', 'Phenotype', 'Polycythemia', 'Potassium', 'Young Adult'] | 26,537,508 | [['C18.452.076.354'], ['C12.777.419.815.279', 'C13.351.968.419.815.279', 'C19.053.800.604.249'], ['Z01.107.757.176'], ['D12.776.157.530.400.175', 'D12.776.543.550.450.175', 'D12.776.543.585.400.175'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['B01.050.150.900.649.313.988.400.11... | ['Diseases [C]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Cryopreservation of mature bovine oocytes by vitrification in straws. | Experiments were conducted to determine optimal conditions for vitrification of in vitro matured bovine oocytes in straws. In the first series of experiments, the effects of stepwise addition before exposure of oocytes to vitrification solution consisting of 30% (v/v) ethylene glycol (EG) with 0.35 M sucrose was tested... | ['Animals', 'Blastomeres', 'Cattle', 'Cell Survival', 'Cryopreservation', 'Female', 'Fertilization in Vitro', 'Oocytes'] | 9,698,432 | [['B01.050'], ['A11.872.700.250.130', 'A16.094'], ['B01.050.150.900.649.313.500.380.271'], ['G04.346'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['E02.875.800.750', 'E05.820.800.750'], ['A05.360.490.690.680', 'A11... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tobacco smoking by pregnant women. Disturbances in metabolism of branched chain amino acids and fetal growth. | Pregnancy alone lowered the plasma AA concentrations of ileu, leu, and val when compared to their concentrations in nonpregnant nonsmokers. Plasma concentrations of val, ileu, and leu were significantly higher in pregnant smokers than in pregnant nonsmokers. Therefore, the utilization of BCAA was more reduced in pregna... | ['Amino Acids, Branched-Chain', 'Embryonic and Fetal Development', 'Female', 'Humans', 'Pregnancy', 'Smoking'] | 8,494,287 | [['D12.125.070'], ['G07.345.500.325', 'G08.686.784.170'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['F01.145.805']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Family matters: effects of birth order, culture, and family dynamics on surrogate decision-making. | Cultural attitudes about medical decision-making and filial expectations may lead some surrogates to experience stress and family conflict. Thirteen focus groups with racially and ethnically diverse English and Spanish speakers from county and Veterans Affairs hospitals, senior centers, and cancer support groups were c... | ['Adult', 'Advance Care Planning', 'Aged', 'Aged, 80 and over', 'Birth Order', 'Communication', 'Conflict, Psychological', 'Cultural Characteristics', 'Decision Making', 'Emotions', 'Family Relations', 'Female', 'Focus Groups', 'Health Literacy', 'Humans', 'Loneliness', 'Male', 'Middle Aged', 'Proxy', 'Qualitative Rese... | 24,383,459 | [['M01.060.116'], ['N04.590.233.624.124'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.829.263.132', 'I01.240.361.160', 'N01.224.361.160', 'N06.850.505.400.400.160'], ['F01.145.209', 'L01.143'], ['F01.658.209'], ['I01.076.201.450.324', 'I01.880.853.100.329'], ['F02.463.785.373'], ['F01.470'], ['F01.829.263.370'... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Impairment, disability and handicap in audiology: towards a consensus. | Within this paper, we argue that the WHO definitions of impairment, disability and handicap have a useful role in understanding the processes of audiological rehabilitation. We have endeavoured to clarify some of the confusions arising from the various uses of the terms in the audiological literature and propose furthe... | ['Activities of Daily Living', 'Correction of Hearing Impairment', 'Disability Evaluation', 'Hearing Disorders', 'Humans', 'Prognosis', 'World Health Organization'] | 1,755,748 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['E02.760.169.063.500.200', 'E02.831.200', 'H02.403.680.600.500', 'N02.421.784.377'], ['E01.370.400'], ['C09.218.458', 'C10.597.751.418', 'C23.888.592.763.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789'], ['N03.540.514.718.800... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
[Tarsorrhaphy of necessity]. | From 1990 to 1994, 68 permanent and temporary tarsorrhaphies have been done: 39 in lagophthalmos, 7 in herpetic keratitis, 2 in zoster keratitis, 1 in neuroparalytic keratitis, 7 in corneal burns and 12 in corneal trophic ulceration with local and general metabolic disturbance. In 38 cases, permanent external tarsorrha... | ['Adult', 'Aged', 'Aged, 80 and over', 'Corneal Diseases', 'Eye Burns', 'Eyelid Diseases', 'Eyelids', 'Female', 'Humans', 'Male', 'Middle Aged'] | 7,654,675 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C11.204'], ['C10.900.300.284.250.250', 'C26.200.503', 'C26.915.300.425.250.250'], ['C11.338'], ['A01.456.505.420.504', 'A09.371.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Awareness of intending to act following parietal cortex resection. | Neuroimaging and neuropsychological studies have provided evidence suggesting that the inferior parietal lobule (IPL) plays a crucial role in the awareness of motor intentions. For instance, patients with IPL lesions caused by stroke selectively differ in the temporal judgements of their intentions to move compared wit... | ['Adult', 'Awareness', 'Brain Neoplasms', 'Confidence Intervals', 'Female', 'Glioma', 'Humans', 'Intention', 'Judgment', 'Magnetic Resonance Imaging', 'Male', 'Neuropsychological Tests', 'Parietal Lobe', 'Psychomotor Performance', 'Reaction Time'] | 18,541,278 | [['M01.060.116'], ['F02.463.188.150'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.650', 'F02.46... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Prostatic osteosis. Retrospective study of 110 cases treated with high-dose estrogens]. | On the basis of 110 prostatic osteoses that were histologically proven, constantly painful and demonstrated by X-ray, treated by early estrogenotherapy using very high doses, backed up by a high-dose maintenance estrogenotherapy, the authors study the clinical, radiological, histological and biological profile of this ... | ['Adult', 'Aged', 'Bone Neoplasms', 'Estradiol Congeners', 'Humans', 'Male', 'Middle Aged', 'Ossification, Heterotopic', 'Prognosis', 'Prostatic Neoplasms', 'Retrospective Studies'] | 119,298 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The interferon stimulated gene 20 protein (ISG20) is an innate defense antiviral factor that discriminates self versus non-self translation. | ISG20 is a broad spectrum antiviral protein thought to directly degrade viral RNA. However, this mechanism of inhibition remains controversial. Using the Vesicular Stomatitis Virus (VSV) as a model RNA virus, we show here that ISG20 interferes with viral replication by decreasing protein synthesis in the absence of RNA... | ['Animals', 'Antiviral Agents', 'Exoribonucleases', 'HeLa Cells', 'Humans', 'Mice', 'Mice, Knockout', 'Protein Biosynthesis', 'RNA Stability', 'RNA, Viral', 'Vesicular Stomatitis', 'Vesiculovirus', 'Virus Replication'] | 31,600,344 | [['B01.050'], ['D27.505.954.122.388'], ['D08.811.277.352.365.300', 'D08.811.277.352.700.375'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact on mortality and fertility of a community-based malaria control programme in Saradidi, Kenya. | Mortality and fertility rates were measured from 1981 to 1983 by prospective registration of vital events as part of a community-based malaria control and health development programme in Saradidi, Kenya. There was no obvious effect of providing chloroquine phosphate for treatment of malaria in each village on mortality... | ['Adolescent', 'Adult', 'Aged', 'Birth Rate', 'Child', 'Child, Preschool', 'Community Health Services', 'Fertility', 'Humans', 'Infant', 'Infant Mortality', 'Infant, Newborn', 'Kenya', 'Malaria', 'Measles', 'Middle Aged', 'Primary Health Care', 'Referral and Consultation', 'Rural Health'] | 3,689,036 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.308.985.775.500', 'N01.224.935.849.500', 'N06.850.505.400.975.775.500', 'N06.850.520.308.985.775.500'], ['M01.060.406'], ['M01.060.406.448'], ['N02.421.143'], ['G08.686.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.30... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
mRNA levels of all three neurofilament proteins decline following nerve transection. | The control of neurofilament (NF) protein gene expression was studied by determining and comparing the levels of mRNA to the heavy (NF-H), mid-sized (NF-M) and light (NF-L) NF protein subunits in rat dorsal root ganglia (DRG) following sciatic nerve transection. mRNA to NF-H (4.5 kb), to NF-M (3.4 kb) and to NF-L (2.5 ... | ['Animals', 'Denervation', 'Ganglia, Spinal', 'Gene Expression Regulation', 'Immunoassay', 'Intermediate Filament Proteins', 'Neurofilament Proteins', 'RNA, Messenger', 'Rats', 'Sciatic Nerve'] | 3,135,913 | [['B01.050'], ['E04.525.210'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['G05.308'], ['E05.478.566', 'E05.601.470'], ['D05.750.078.593', 'D12.776.220.475'], ['D05.750.078.593.630', 'D12.776.220.475.630', 'D12.776.631.630'], ['D13.444.735.544'], ['B01.050.150.900.649.313.992.635.505.700'], ['A0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Functional connectivity between simple cells and complex cells in cat striate cortex. | In the cat primary visual cortex, neurons are classified into the two main categories of simple cells and complex cells based on their response properties. According to the hierarchical model, complex receptive fields derive from convergent inputs of simple cells with similar orientation preferences. This model receive... | ['Animals', 'Cats', 'Electrophysiology', 'Models, Neurological', 'Neural Pathways', 'Neurons', 'Visual Cortex'] | 10,196,530 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['H01.158.344.528', 'H01.158.782.236'], ['E05.599.395.642'], ['A08.612'], ['A08.675', 'A11.671'], ['A08.186.211.200.885.287.500.571.735', 'A08.186.211.200.885.287.500.814.953']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Analysis of proteins in normal and regenerating rat liver using two-dimensional electrophoresis]. | The major proteins of homogenate, cytosol, nuclei and nuclear membrane extract from normal and regenerating rat liver were studied by two-dimensional electrophoresis with a view of detecting proteins involved in DNA replication regulation. Essential quantitative differences in three out of 200 polypeptides separated as... | ['Animals', 'Electrophoresis, Gel, Two-Dimensional', 'Liver', 'Liver Regeneration', 'Male', 'Molecular Weight', 'Proteins', 'Rats'] | 2,633,804 | [['B01.050'], ['E05.196.401.250', 'E05.301.300.230'], ['A03.620'], ['G10.261.475', 'G16.762.468'], ['G02.494'], ['D12.776'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic studies of an Escherichia coli K-12 temperature-sensitive mutant defective in membrane protein synthesis. | The mutant divE42(Ts) of Escherichia coli K-12, defective in the synthesis of membrane proteins and in the transcription of the lac operon at high temperature, has been further characterized. It was found that a mutation (divE42) located at about min 22 on the E. coli chromosome map is responsible for the Lac- phenotyp... | ['Bacterial Proteins', 'Cell Membrane', 'Chromosome Mapping', 'Escherichia coli', 'Genes, Recessive', 'Lac Operon', 'Mutation', 'Temperature', 'Transcription, Genetic', 'Transduction, Genetic'] | 374,381 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exact analysis of dose response for multiple correlated binary outcomes. | The neurotoxicity of a substance is often tested using animal bioassays. In the functional observational battery, animals are exposed to a test agent and multiple outcomes are recorded to assess toxicity, using approximately 40 animals measured on up to 30 different items. This design gives rise to a challenging statis... | ['Algorithms', 'Animals', 'Biological Assay', 'Biometry', 'Confidence Intervals', 'Data Interpretation, Statistical', 'Dose-Response Relationship, Drug', 'Humans', 'Models, Statistical', 'Neurotoxins', 'Outcome Assessment, Health Care', 'Tetrachloroethylene'] | 15,032,792 | [['G17.035', 'L01.224.050'], ['B01.050'], ['E05.091'], ['E05.318.740.225', 'N06.850.505.200'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Cytotoxic triterpenoid saponins of Albizia gummifera from the Madagascar rain forest. | Bioassay-guided fractionation of an EtOH extract obtained from the roots of the Madagascan plant Albizia gummifera led to the isolation of three new cytotoxic oleanane-type triterpenoid saponins, gummiferaosides A-C (1-3). The structures of these new compounds were elucidated using 1D and 2D NMR experiments and mass sp... | ['Albizzia', 'Antineoplastic Agents, Phytogenic', 'Drug Screening Assays, Antitumor', 'Female', 'Humans', 'Inhibitory Concentration 50', 'Madagascar', 'Molecular Structure', 'Ovarian Neoplasms', 'Plants, Medicinal', 'Saponins', 'Triterpenes'] | 17,263,578 | [['B01.650.940.800.575.912.250.401.051'], ['D27.505.954.248.179'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.940.350', 'G07.690.936.563'], ['Z01.639.520.500'], ['G02.111.570', 'G02.466'], ['C04.588.322.455', 'C13.351.500.056.630.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
A transmembrane-anchored rat RAE-1-like transcript as a ligand for NKR-P2, the rat ortholog of human and mouse NKG2D. | NKG2D is a potent activating immunoreceptor that has been extensively characterized in NK cells and shown to lend costimulatory functions in CD8(+) T cells under certain conditions. The list is growing of ligands for NKG2D, which are distantly related to MHC class I molecule and are often up-regulated during cellular d... | ['Amino Acid Sequence', 'Animals', 'Blotting, Northern', 'Cell Line', 'Flow Cytometry', 'Humans', 'Immunoblotting', 'Killer Cells, Natural', 'Lectins, C-Type', 'Ligands', 'Membrane Proteins', 'Mice', 'Microscopy, Confocal', 'Molecular Sequence Data', 'NK Cell Lectin-Like Receptor Subfamily K', 'Rats', 'Receptors, Immun... | 16,323,246 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['A11.251.210'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.6... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Environmental tobacco exposure is associated with vaccine modified measles in junior high school students. | Vaccine modified measles (VMM) affects individuals with attenuated vaccine induced immunity. An outbreak of measles occurred in a junior high school, starting from an unvaccinated eighth-grade student who developed natural measles and affected a majority of students who were immunized with a low potent strain of measle... | ['Adolescent', 'Child', 'Cotinine', 'Environmental Exposure', 'Female', 'Humans', 'Male', 'Measles', 'Risk Assessment', 'Surveys and Questionnaires', 'Tobacco Smoke Pollution'] | 25,959,288 | [['M01.060.057'], ['M01.060.406'], ['D03.383.773.812.180'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.925.782.580.600.500.500'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['E05.318.308.980', 'N05.715... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
New Molecular Mechanism Underlying Myc-Mediated Cytochrome P450 2E1 Upregulation in Apoptosis and Energy Metabolism in the Myocardium. | Background Canonical studies indicate that cytochrome P450 2E1 ( CYP 2E1) plays a critical role in the metabolism of xenobiotics and ultimately participates in tissue damage. CYP 2E1 upregulates in the pathophysiological development of multiple diseases; however, the mechanism of CYP 2E1 upregulation, particularly in h... | ['Animals', 'Apoptosis', 'Cells, Cultured', 'Cytochrome P-450 CYP2E1', 'Disease Models, Animal', 'Energy Metabolism', 'Gene Expression Regulation', 'Humans', 'Immunoblotting', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Myocardial Ischemia', 'Myocardium', 'RNA', 'Up-Regulation'] | 30,563,421 | [['B01.050'], ['G04.146.954.035'], ['A11.251'], ['D08.244.453.491.375', 'D08.811.682.662.582.338', 'D08.811.682.690.708.170.450.375', 'D12.776.422.220.453.491.375'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G03.295'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Visual deprivation and foveation characteristics both underlie visual acuity deficits in idiopathic infantile nystagmus. | PURPOSE: Children with idiopathic infantile nystagmus (IIN) exhibit visual acuity deficits that have been modeled in terms of foveation characteristics of the nystagmus waveform. Here we present evidence for an additional component of acuity loss associated with the deprivation experienced during the sensitive period o... | ['Child', 'Child, Preschool', 'Eye Movements', 'Fovea Centralis', 'Humans', 'Infant', 'Models, Theoretical', 'Nystagmus, Congenital', 'Sensory Deprivation', 'Vision Disorders', 'Vision, Binocular', 'Visual Acuity'] | 23,687,170 | [['M01.060.406'], ['M01.060.406.448'], ['G11.427.410.140', 'G14.350'], ['A09.371.729.522.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.599'], ['C10.292.562.675.300', 'C11.590.400.300', 'C16.614.643'], ['F02.463.593.696'], ['C10.597.751.941', 'C11.966', 'C23.888.592.763.941'], ['F02.463.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Distribution of fluorescent microspheres in vascular space and parenchymal organs of intact nude rats. | PURPOSE: To assess kinetics of elimination of different sized microspheres (MS) from the blood pool and tendency of their distribution in parenchymal organs of intact nude rats.MATERIALS AND METHODS: A mixture of 1 microm and 3 microm MS in phosphate-buffered saline was injected intravenously into eight rats under intr... | ['Animals', 'Blood Vessels', 'Flow Cytometry', 'Fluorescent Dyes', 'Male', 'Microscopy, Fluorescence', 'Microspheres', 'Rats', 'Rats, Nude', 'Trypsin'] | 19,657,864 | [['B01.050'], ['A07.015'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['E01.370.350.515.458', 'E05.595.458'], ['E07.565'], ['B01.050.150.900.649... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The pro-inflammatory profile of depressed patients is (partly) related to obesity. | Many people with major depressive disorder (MDD) show evidence of systemic inflammation, including elevations in inflammatory factors, but the cause is unclear. The purpose of this analysis was to determine if obesity might contribute to the pro-inflammatory state in MDD patients. Blood was obtained from 135 MDD patien... | ['Adiponectin', 'Adult', 'C-Reactive Protein', 'Depressive Disorder, Major', 'Female', 'Humans', 'Interleukin-6', 'Leptin', 'Male', 'Middle Aged', 'Obesity', 'Tumor Necrosis Factor-alpha'] | 26,424,427 | [['D06.472.699.042.249', 'D12.644.276.024.249', 'D12.644.548.011.249', 'D12.776.467.024.249', 'D23.529.024.249'], ['M01.060.116'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['F03.600.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Site-directed mutagenesis of the 'zinc finger' DNA-binding domain of the nitrogen-regulatory protein NIT2 of Neurospora. | The major nitrogen-regulatory gene nit-2 of Neurospora crassa activates the expression of numerous unlinked structural genes which specify nitrogen-catabolic enzymes during conditions of nitrogen limitation. The nit-2 gene encodes a regulatory protein of 1036 amino acid residues with a single 'zinc finger' and a downst... | ['Amino Acid Sequence', 'DNA-Binding Proteins', 'Fungal Proteins', 'Gene Expression Regulation, Fungal', 'Genes, Fungal', 'Genes, Regulator', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Neurospora crassa', 'Protein Biosynthesis', 'Recombinant Fusion Proteins', 'Transcription Factors', 'Transcription, Gene... | 2,150,539 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.260'], ['D12.776.354'], ['G05.308.330'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['G05.360.340.024.340.425'], ['L01.453.245.667'], ['E05.393.420.601.575'], ['B01.300.107.800.629.564'], ['G02.111.660.871', 'G03.734.871'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cholecalciferol, Ergosterol, and Cholesterol Enhance the Antibiotic Activity of Drugs. | Background: This is the first report demonstrating the antibiotic-modifying activity of cholecalciferol.AIM: In this study, cholecalciferol was evaluated against multiresistant strains of Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli.METHODS: The antibacterial and modulatory effects of cholecalcif... | ['Anti-Bacterial Agents', 'Cholecalciferol', 'Cholesterol', 'Ergosterol', 'Microbial Sensitivity Tests'] | 31,124,408 | [['D27.505.954.122.085'], ['D04.210.500.247.222.159', 'D04.210.500.247.808.146', 'D04.210.500.812.768.196', 'D10.570.938.146'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.222.537'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microsurgical Reconstruction of the Plantar Foot: Long-Term Functional Outcomes and Quality of Life. | BACKGROUND: When faced with plantar defects, reconstruction of the weight-bearing areas presents unique surgical challenges. Several free flap modalities have been described in this respect, but there remains debate regarding the best-suited flap modality. Aim of this study was to compare free muscle and non-neurotize... | ['Blood Flow Velocity', 'Diabetic Angiopathies', 'Female', 'Foot', 'Free Tissue Flaps', 'Humans', 'Male', 'Middle Aged', 'Quality of Life', 'Reconstructive Surgical Procedures', 'Treatment Outcome', 'Weight-Bearing'] | 30,625,504 | [['E01.370.370.130', 'G09.330.380.630.080'], ['C14.907.320', 'C19.246.099.500'], ['A01.378.610.250'], ['A10.850.710.500', 'E07.862.710.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E04.680'], ['E01.789.800', 'N04.761.559.590.800... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Gangliosides protect human melanoma cells from ionizing radiation-induced clonogenic cell death. | With an experimental model of spontaneous lung metastases of melanoma developed in this laboratory, a range of sublines (variants and clones) with different metastatic potential and ganglioside expression was established from a single human melanoma cell line M4Be. Using an in vitro clonogenic assay and provided that c... | ['Animals', 'Antibodies, Monoclonal', 'Cattle', 'Cell Death', 'Cell Survival', 'Clone Cells', 'Cobalt Radioisotopes', 'Dose-Response Relationship, Radiation', 'Flow Cytometry', 'Fumonisins', 'G(M1) Ganglioside', 'Gamma Rays', 'Gangliosides', 'Humans', 'Lung Neoplasms', 'Melanoma', 'Mycotoxins', 'Neuraminidase', 'Partic... | 8,781,968 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['B01.050.150.900.649.313.500.380.271'], ['G04.146'], ['G04.346'], ['A11.251.353'], ['D01.268.556.185.500.354', 'D01.268.956.155.500.354', 'D01.496.239.354', 'D01.496.749.256', 'D01.552.544.185.500.354'], ['E05.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Personalization of structural PDB files. | PDB format is most commonly applied by various programs to define three-dimensional structure of biomolecules. However, the programs often use different versions of the format. Thus far, no comprehensive solution for unifying the PDB formats has been developed. Here we present an open-source, Python-based tool called P... | ['Databases, Protein', 'Internet', 'Protein Conformation', 'Software'] | 24,350,306 | [['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['L01.224.230.110.500'], ['G02.111.570.820.709'], ['L01.224.900']] | ['Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Leaving foster or residential care: a participatory study of care leavers' experiences of health and social care transitions. | BACKGROUND: Young people in residential or foster care experience multiple transitions around their 18th birthday without the long term and consistent support from their family of origin that most of their peers can expect. We report a mixed methods qualitative study of transitions across health and social care service... | ['Adolescent', 'Adolescent Health Services', 'Attitude to Health', 'Community Participation', 'Consumer Behavior', 'England', 'Foster Home Care', 'Humans', 'Interviews as Topic', 'Residential Facilities', 'Social Work', 'Transition to Adult Care', 'Young Adult'] | 27,896,832 | [['M01.060.057'], ['N02.421.044'], ['F01.100.150', 'N05.300.150'], ['N02.421.143.212', 'N03.540.245.360'], ['F01.145.236'], ['Z01.542.363.300'], ['E02.760.352', 'I01.880.787.416', 'N02.421.143.452', 'N02.421.585.352'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Serotonin nerve fibers in the primary visual cortex of the monkey. Quantitative and immunoelectronmicroscopical analysis. | A quantitative and immunoelectronmicroscopical analysis of serotonin nerve fibers in the primary visual cortex of the monkey (Macaca fuscata) was made using a sensitive immunoperoxidase method for serotonin. The overall numerical density of serotonin-containing varicosities in the primate striate cortex was approximate... | ['Animals', 'Macaca', 'Male', 'Microscopy, Electron', 'Nerve Fibers', 'Serotonin', 'Synapses', 'Visual Cortex'] | 6,721,216 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.199.120.510'], ['E01.370.350.515.402', 'E05.595.402'], ['A08.675.542', 'A11.671.501'], ['D02.092.211.215.801.852', 'D03.633.100.473.914.814', 'D23.469.050.650'], ['A08.850', 'A11.284.149.165.420.780'], ['A08.186.211.200.885.287.500.571.735', 'A08.186.211.200.885.287.5... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A microfluidic system for investigation of extravascular transport and cellular uptake of drugs in tumors. | Three-dimensional (3D) tumor models have been established in various microfluidic systems for drug delivery and resistance studies in vitro. However, one of the main drawbacks of these models is non-uniform distribution of cells, leaving regions with very low cell density within the 3D structures. As a result, molecula... | ['Animals', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Mice', 'Microfluidics', 'Models, Theoretical', 'Organ Culture Techniques', 'Plasmacytoma'] | 22,124,930 | [['B01.050'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.830.666', 'H01.671.808.500', 'J01.897.520.500.500'], ['E05.599'], ['E05.481.500.484'], ['C04.557.595.600', 'C20.683.515.880']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Cell culture-PCR technique for detection of infectious cytomegalovirus in peripheral blood. | We determined the efficacy of PCR for the direct detection of infectious cytomegalovirus (CMV) in specimen-inoculated MRC-5 tube cultures (cell culture-PCR [CC-PCR]). Parallel testing was performed by a shell vial assay-indirect immunofluorescence assay (SVA-IFA) and isolation (conventional MRC tube cultures [TC-CPE]. ... | ['Blood', 'Cytomegalovirus', 'Cytomegalovirus Infections', 'Cytopathogenic Effect, Viral', 'Diagnostic Errors', 'Evaluation Studies as Topic', 'Fluorescent Antibody Technique', 'Humans', 'Polymerase Chain Reaction', 'Sensitivity and Specificity', 'Viremia', 'Virology'] | 7,615,769 | [['A12.207.152', 'A15.145'], ['B04.280.382.150.150'], ['C01.925.256.466.245'], ['E01.370.225.500.384.235', 'E05.200.500.384.235', 'E05.242.384.235', 'G06.920.190'], ['E01.354', 'N02.421.450.280'], ['E05.337', 'N05.715.360.335'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', '... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Alcohol consumption during pregnancy in nonindigenous west Australian women. | BACKGROUND: High alcohol intake in pregnancy has been linked to abnormal fetal development. There are limited published data in Australia on standard drinks of alcohol consumed on a typical occasion during the periconceptional period or pregnancy.METHODS: During 1995 to 1997, a 10% random sample of all nonindigenous wo... | ['Adolescent', 'Adult', 'Alcohol Drinking', 'Cross-Sectional Studies', 'Female', 'Health Behavior', 'Health Surveys', 'Humans', 'Pregnancy', 'Pregnancy Trimesters', 'Prevalence', 'Risk Factors', 'Western Australia'] | 17,250,620 | [['M01.060.057'], ['M01.060.116'], ['F01.145.317.269'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.488'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['G08.686.707'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hybrid EEG-fNIRS Asynchronous Brain-Computer Interface for Multiple Motor Tasks. | Non-invasive Brain-Computer Interfaces (BCI) have demonstrated great promise for neuroprosthetics and assistive devices. Here we aim to investigate methods to combine Electroencephalography (EEG) and functional Near-Infrared Spectroscopy (fNIRS) in an asynchronous Sensory Motor rhythm (SMR)-based BCI. We attempted to c... | ['Adult', 'Algorithms', 'Arm', 'Brain-Computer Interfaces', 'Electroencephalography', 'Functional Laterality', 'Hand', 'Humans', 'Male', 'Middle Aged', 'Motor Cortex', 'Movement', 'Photic Stimulation', 'Psychomotor Performance', 'Reproducibility of Results', 'Spectroscopy, Near-Infrared', 'Young Adult'] | 26,730,580 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['A01.378.800.075'], ['E07.305.076'], ['E01.370.376.300', 'E01.370.405.245'], ['F02.830.297.425', 'G11.561.225.425'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
DNA Repair Mechanism Gene, XRCC1A ( Arg194Trp) but not XRCC3 ( Thr241Met) Polymorphism Increased the Risk of Breast Cancer in Premenopausal Females: A Case-Control Study in Northeastern Region of India. | X-ray repair cross complementary group gene is one of the most studied candidate gene involved in different types of cancers. Studies have shown that X-ray repair cross complementary genes are significantly associated with increased risk of breast cancer in females. Moreover, studies have revealed that X-ray repair cro... | ['Adult', 'Breast Neoplasms', 'DNA Repair', 'DNA-Binding Proteins', 'Female', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'India', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Premenopause', 'Risk Factors', 'X-ray Repair Cross Complementing Protein 1'] | 29,332,455 | [['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['G02.111.222', 'G05.219'], ['D12.776.260'], ['E05.393.385'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['M01.060.116.630'], ['G05.365.795.598'], ['G08.686.157.500.812', 'G08.686.841.24... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Clonal B lymphocytes lack bcr rearrangement in Ph-positive chronic myelogenous leukaemia. | Philadelphia (Ph) chromosome-positive chronic myelogenous leukaemia (CML) was studied in a subject heterozygous for the X chromosome-linked alloenzyme system of glucose-6-phosphate dehydrogenase (G6PD). Determination of G6PD mosaicism showed homogeneous expression in granulocytes, erythrocytes and platelets. Cytogeneti... | ['B-Lymphocytes', 'Blotting, Southern', 'Chronic Disease', 'Female', 'Gene Rearrangement, B-Lymphocyte', 'Glucosephosphate Dehydrogenase', 'Humans', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Middle Aged', 'Neoplastic Stem Cells', 'Philadelphia Chromosome'] | 2,803,977 | [['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['C23.550.291.500'], ['G05.344.401', 'G12.500.274'], ['D08.811.682.047.150.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.33... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The nanostructures of amorphous silicas. | Topologically modeled amorphized silica structures have been refined using a molecular dynamics simulation technique. Several metastable structures with substantially different medium-range connectivities, as characterized by primitive ring statistics, were obtained. Whereas the total correlation function is insensitiv... | ['Crystallization', 'Microscopy, Electron', 'Models, Molecular', 'Nanotechnology', 'Silicon Dioxide', 'X-Ray Diffraction'] | 12,533,201 | [['E05.196.300', 'G02.171'], ['E01.370.350.515.402', 'E05.595.402'], ['E05.599.595'], ['H01.603', 'J01.897.520.600'], ['D01.578.750', 'D01.650.550.825', 'D01.837.725'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950', 'G02.965']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[Pulmonary transplantation in Quebec]. | Quebec performed the first lung transplantation in 1963 which was unsuccessful in term of survival rate at that time. Since 1985, as the advancement of knowledge of pulmonary pathologies and of surgical techniques, 18 heart lung transplantations and 30 lung transplantations have been performed. | ['Humans', 'Lung Transplantation', 'Postoperative Complications', 'Quebec', 'Survival Rate'] | 1,771,692 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.928.600.495', 'E04.936.450.495'], ['C23.550.767'], ['Z01.107.567.176.791'], ['E05.318.308.985.550.900', 'N01.224.935.698.826', 'N06.850.505.400.975.550.900', 'N06.850.520.308.985.550.900']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Natural Sesquiterpene Lactones as Potential Trypanocidal Therapeutic Agents: A Review. | Chagas' disease and Human African Trypanosomiasis are parasitic diseases that remain major health problems, mainly among the poorest and the most marginalized communities from Latin America and Africa. The scarcity of effective chemotherapy, due to the low investment in the research and development (R&D) of new drugs, ... | ['Animals', 'Humans', 'Lactones', 'Plants, Medicinal', 'Sesquiterpenes', 'Trypanocidal Agents', 'Trypanosoma brucei rhodesiense', 'Trypanosoma cruzi', 'Trypanosomiasis'] | 30,549,624 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.540'], ['B01.650.560'], ['D02.455.849.765'], ['D27.505.954.122.250.100.875'], ['B01.268.475.868.887.115'], ['B01.268.475.868.887.140'], ['C01.610.752.300.900']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Method of recording cerebrospinal fluid pressure at three anatomic places in conscious and unrestrained adult wistar rats. | There does not appear to be a consensus on the normal values of cerebrospinal fluid pressure (Pcsf) in rats because of the different conditions in which each experiment has been done. Anaesthesia, restraint or recordings from different anatomical places and the use of simultaneous infusions could produce a great variab... | ['Anesthesia', 'Animals', 'Catheterization', 'Cerebral Ventricles', 'Cerebral Ventriculography', 'Cerebrospinal Fluid Pressure', 'Cisterna Magna', 'Male', 'Myelography', 'Rats', 'Rats, Wistar', 'Subarachnoid Space'] | 8,848,288 | [['E03.155'], ['B01.050'], ['E02.148', 'E05.157'], ['A08.186.211.140'], ['E01.370.350.578.937.190', 'E01.370.350.700.560.190', 'E01.370.376.537.750.190', 'E05.629.937.190'], ['G11.561.170'], ['A08.186.566.166.686.351'], ['E01.370.350.578.937.505', 'E01.370.350.700.560.505', 'E01.370.376.537.750.505', 'E05.629.937.505']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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