Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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A laser flash photolysis study of fenofibric acid in aqueous buffered media: unexpected triplet state inversion in a derivative of 4-alkoxybenzophenone. | Laser excitation of aqueous solutions of fenofibric acid (FA) at pH 7.4 show the formation of two reaction intermediates, the triplet state and the hydrated electron. The former is longer lived in water than in acetonitrile; its anionic form decays irreversibly by decarboxylation to give a carbanion that protonates bef... | ['Benzophenones', 'Buffers', 'Fenofibrate', 'Lasers', 'Photolysis', 'Water'] | 11,950,084 | [['D02.455.426.559.389.134', 'D02.522.223'], ['D27.720.470.280'], ['D02.241.081.114.968.500.625', 'D02.355.726.305.625', 'D02.455.426.559.389.134.750', 'D02.455.426.559.389.657.654.305.625', 'D02.522.223.750'], ['E07.632.490', 'E07.710.520'], ['G02.740.685'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of antianaphylactic agents on substance-P induced histamine release from rat peritoneal mast cells. | Substance P is known to be a potent histamine liberator for mast cells. The influence of antianaphylactic agents, disodium cromoglycate (DSCG), ketotifen, and tranilast was studied on substance-P and compound 48/80-induced histamine release from rat peritoneal mast cells. Substance-P induced histamine release was inhib... | ['Animals', 'Cromolyn Sodium', 'Depression, Chemical', 'Female', 'Histamine Release', 'Ketotifen', 'Male', 'Mast Cells', 'Peritoneal Cavity', 'Rats', 'Rats, Inbred Strains', 'Substance P', 'ortho-Aminobenzoates', 'p-Methoxy-N-methylphenethylamine'] | 2,454,082 | [['B01.050'], ['D03.383.663.283.266.300', 'D03.633.100.150.266.300'], ['G07.690.773.750'], ['G12.350'], ['D02.886.778.370', 'D03.383.621.370', 'D03.383.903.370'], ['A11.329.427', 'A15.382.652'], ['A01.923.047.025.600.678'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.31... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Functional implication of disulfide bond, Cys250 -Cys283, in bovine chymosin. | The reduction, carboxymethylation and mercuration of disulfide bond, Cys250-Cys283, located on the surface of bovine chymosin molecule resulted in the loss of about 25% of enzyme activity, suggesting that Cys250-Cys283 is not intimately involved in catalytic mechanism. Cys250 and Cys283 were substituted with Asp. and S... | ['Animals', 'Base Sequence', 'Binding Sites', 'Catalysis', 'Cattle', 'Chymosin', 'Cysteine', 'DNA', 'Disulfides', 'Genes', 'Molecular Sequence Data', 'Molecular Structure', 'Mutagenesis, Site-Directed', 'Protein Conformation', 'Structure-Activity Relationship'] | 1,530,626 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['G02.130'], ['B01.050.150.900.649.313.500.380.271'], ['D08.811.277.656.074.500.200', 'D08.811.277.656.300.048.200'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D13.444.308'], ['D01.248.497... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The catalytic domain of RNase E shows inherent 3' to 5' directionality in cleavage site selection. | RNase E, a multifunctional endoribonuclease of Escherichia coli, attacks substrates at highly specific sites. By using synthetic oligoribonucleotides containing repeats of identical target sequences protected from cleavage by 2'-O-methylated nucleotide substitutions at specific positions, we investigated how RNase E id... | ['Base Sequence', 'Catalytic Domain', 'Endoribonucleases', 'Escherichia coli', 'Kinetics', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'Oligoribonucleotides', 'Plasmids', 'Substrate Specificity'] | 12,417,756 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D08.811.277.352.355.350', 'D08.811.277.352.700.350'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.374.661', 'G02.111.490'], ['L01.453.245.667'], ['G02.111.570.820.486', 'G05.360.58... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A simple, modified arthroscopic suture fixation of avulsion fracture of the tibial intercondylar eminence in children. | The purpose of this study was to describe a simple and modified technique for arthroscopic suture fixation in a 12-year-old boy who sustained a displaced type III intercondylar eminence of the tibial. The arthroscopic fixation was modified by using the Arthrex suture lasso device to place two nonabsorbable sutures into... | ['Anterior Cruciate Ligament', 'Arthroscopy', 'Bicycling', 'Child', 'Fractures, Cartilage', 'Humans', 'Joint Dislocations', 'Knee Injuries', 'Male', 'Range of Motion, Articular', 'Recovery of Function', 'Suture Techniques', 'Tibial Fractures'] | 21,048,518 | [['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['I03.450.642.845.140'], ['M01.060.406'], ['C26.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['C26.558.554'], ['E01.370.600.700', 'G11.427.760'], ['G16.75... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Biphasic regulation of polymorphonuclear leukocyte spreading by polyphenolic compounds with pyrogallol moieties. | Green tea polyphenols have been reported to have anti-inflammatory activities, although the molecular mechanisms responsible for this effect remain unclear. In the present study, we examined the effect of green tea extract and a variety of polyphenolic compounds on spreading of peripheral blood polymorphonuclear leukoc... | ['Animals', 'Camellia sinensis', 'Catechin', 'Cell Adhesion', 'Cell Surface Extensions', 'Cells, Cultured', 'Chemotaxis', 'Fibrinogen', 'Neutrophils', 'Plant Extracts', 'Pyrogallol', 'Swine', 'Tannins'] | 19,524,070 | [['B01.050'], ['B01.650.940.800.575.912.250.341.998.500.500'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['G04.022'], ['A11.284.180'], ['A11.251'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.42... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Laparoscopic orchiectomy and subsequent internal ring closure for extra-abdominal testicular nubbin in children. | OBJECTIVES: To present our preliminary experience with laparoscopic groin exploration and subsequent laparoscopic orchiectomy and internal ring closure for testicular nubbin in children and discuss the usefulness of our new treatment strategy. The advantages of laparoscopic orchiopexy for intra-abdominal testis are the... | ['Child', 'Child, Preschool', 'Cryptorchidism', 'Humans', 'Infant', 'Laparoscopy', 'Male', 'Orchiectomy'] | 19,118,886 | [['M01.060.406'], ['M01.060.406.448'], ['C12.294.829.258', 'C12.706.258', 'C16.131.939.258', 'C19.391.829.258'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E04.270.282.679', 'E04.950.165.679', 'E04.950.774.860.618']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Canine and feline aural hematoma: clinical, experimental, and clinicopathologic observations. | The pathogenesis of canine and feline aural hematoma (AH) was investigated. Clinical observations, selected experimental procedures, and clinicopathologic examinations were done on 40 dogs and 20 cats affected with AH. Eighteen healthy dogs and 14 healthy cats were used as the controls. The results of this investigatio... | ['Animals', 'Antibodies, Antinuclear', 'Blood Proteins', 'Cat Diseases', 'Cats', 'Coombs Test', 'Dog Diseases', 'Dogs', 'Ear Diseases', 'Ear, External', 'Exudates and Transudates', 'Female', 'Hematoma', 'Immunoglobulin G', 'Male'] | 3,490,809 | [['B01.050'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['D12.776.124'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['E01.370.225.812.735.050.375.150', 'E05.200.812.735.050.375.150', 'E05.478.594.760.050.375.150'], ['C22.268'], ['B01.05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis by the DNA primase of Drosophila melanogaster of a primer with a unique chain length. | The primase associated with the DNA polymerase alpha from embryos of Drosophila melanogaster catalyzes the synthesis of ribo-oligonucleotide primers on single-stranded M13 DNA or polydeoxythymidylate templates, which can be elongated by DNA polymerase action [Conaway, R. C. & Lehman, I. R. (1982) Proc, Natl. Acad. Sci,... | ['Animals', 'Base Sequence', 'DNA Primase', 'DNA Replication', 'DNA, Viral', 'DNA-Directed DNA Polymerase', 'Deoxyribonucleotides', 'Drosophila melanogaster', 'Molecular Weight', 'RNA Nucleotidyltransferases', 'Ribonucleotides', 'Substrate Specificity', 'Templates, Genetic'] | 6,812,052 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.913.696.445.735.270.375'], ['G02.111.225', 'G05.226'], ['D13.444.308.568'], ['D08.811.913.696.445.308.300'], ['D13.695.201'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G02.494'], ['D08.811.913.696.445.735'], ['D13.695.827'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The influence of behavioural and psychological factors on medication adherence over time in rheumatoid arthritis patients: a study in the biologics era. | OBJECTIVES: To investigate levels of self-reported adherence to biologic treatment and establish the contribution of demographic, physical and psychological factors to biologic medication adherence in an RA cohort.METHODS: Adalimumab-treated patients were recruited through the British Society for Rheumatology Biologics... | ['Adalimumab', 'Adult', 'Arthritis, Rheumatoid', 'Biological Products', 'Culture', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Medication Adherence', 'Middle Aged', 'Patient Compliance', 'Retrospective Studies', 'Self Report', 'Severity of Illness Index', 'Social Support', 'Surveys and Questionnaires', 'Time F... | 25,972,390 | [['D12.776.124.486.485.114.224.060.250', 'D12.776.124.790.651.114.224.060.250', 'D12.776.377.715.548.114.224.200.250'], ['M01.060.116'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D20.215'], ['I01.076.201.450', 'I01.880.853.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.3... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Pharmacokinetics of tiaprofenic acid in normal rabbits and rabbits subjected to joint immobilisation. | In a previous study, tiaprofenic acid (TA) was administered daily over a 30-day period at 5 and 10 mg/kg of body weight subcutaneously (s.c.) to animals with arthritis induced by immobilisation. The 10 mg/kg dose exacerbated the loss of proteoglycan from joint cartilage but the 5 mg/kg dose showed protective effects on... | ['Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Arthritis', 'Cartilage, Articular', 'Chromatography, High Pressure Liquid', 'Immobilization', 'Indicators and Reagents', 'Joints', 'Propionates', 'Rabbits', 'Spectrophotometry, Ultraviolet', 'Synovial Fluid'] | 8,285,141 | [['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['C05.550.114'], ['A02.165.407.150', 'A02.835.583.192'], ['E05.196.181.400.300'], ['E05.472'], ['D27.720.470.410'], ['A02.835.583'], ['D02.241.081.751', 'D10.251.400.706'], ['B01.050.150.900.649.313.968.700'], ['E05.196.712... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transcriptomics does not show adverse effects of beta-carotene in A/J mice exposed to smoke for 2 weeks. | Beta-carotene (betaC) supplementation in smokers was unexpectedly associated with increased incidence of lung cancer versus smoking alone. We performed a study in A/J mice to explore possible betaC/cigarette smoke (CS) interactions potentially influencing lung cancer risk in smokers. A/J mice received a diet containing... | ['Animals', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Environmental Exposure', 'Gene Expression Regulation', 'Lung', 'Male', 'Mice', 'Proteome', 'Tars', 'Tobacco Smoke Pollution', 'Transcription Factors', 'beta Carotene'] | 17,707,332 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['N06.850.460.350'], ['G05.308'], ['A04.411'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.817'], ['D20.749'], ['D20.633.937.680', 'N06.850.460.100.555'], ['D12.776.930'], ['D02.455.326.271.665.202.123', 'D02.455.426.392.368.367.379.2... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Microbiological and clinical effects of a dentifrice containing zinc citrate and Triclosan in the human experimental gingivitis model. | A partial mouth experimental gingivitis model was employed to establish the effect of a dentifrice containing 0.2% Triclosan and 0.5% zinc citrate on the development of chronic gingivitis. In addition, changes in the plaque flora associated with the developing gingivitis have been monitored. Following a period of strin... | ['Actinomyces', 'Adolescent', 'Adult', 'Bacteria', 'Citrates', 'Citric Acid', 'Dental Plaque', 'Dentifrices', 'Female', 'Gingival Hemorrhage', 'Gingivitis', 'Humans', 'Male', 'Middle Aged', 'Placebos', 'Streptococcus', 'Triclosan'] | 2,212,087 | [['B03.510.024.049.050.050', 'B03.510.460.400.400.049.049.178'], ['M01.060.057'], ['M01.060.116'], ['B03'], ['D02.241.081.901.434'], ['D02.241.081.901.434.249'], ['C07.793.208.377'], ['D25.376', 'D27.720.269.380', 'J01.637.051.376'], ['C07.465.625.446', 'C07.465.714.258.250', 'C23.550.414.922.500'], ['C01.408', 'C07.46... | ['Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Alteration in insulin-like growth factor-binding proteins (IGFBPs) and IGFBP-3 protease activity in serum and urine from acute and chronic renal failure. | The insulin-like growth factors, IGF-I and IGF-II, are proteins that promote cellular growth and differentiation of various organs, including the kidney. These peptides interact with high affinity cell surface receptors and bind to a family of IGF-binding proteins (IGFBPs). Altered serum and urinary IGFBP patterns in c... | ['Acute Kidney Injury', 'Adolescent', 'Adult', 'Aprotinin', 'Blotting, Western', 'Carrier Proteins', 'Child', 'Child, Preschool', 'Endopeptidases', 'Female', 'Humans', 'Insulin-Like Growth Factor Binding Proteins', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Molecular Weight', 'alpha-2-Antiplasmin'] | 7,525,635 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.057'], ['M01.060.116'], ['D12.776.083'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.157'], ['M01.060.406'], ['M01.060.406.448'], ['D08.811.277.656.300'], ['B01.050.150.900.649.313.988.400.1... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Management of violence in the workplace: a New Zealand survey. | OBJECTIVE: To estimate the rate of adverse events to staff, to survey the use of various preventative measures, and to assess any association between these factors and the reported event rate.METHOD: An anonymous postal nation-wide survey of violence reported to managers of psychiatric units in New Zealand.RESULTS: The... | ['Adolescent', 'Adult', 'Child', 'Female', 'Humans', 'Male', 'Mental Disorders', 'New Zealand', 'Surveys and Questionnaires', 'Violence', 'Workplace'] | 12,072,125 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['Z01.639.760.747', 'Z01.678.100.747'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['I01.198.240.856', 'I01.880.735.900'], ['N01.824.245.925', 'N04.452.677.975']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Flow in the anterior chamber of the eye with an implanted iris-fixated artificial lens. | Flow in the aqueous humour that fills the anterior chamber of the eye occurs in response to the production and drainage of the aqueous humour, and also due to buoyancy effects produced by thermal gradients. Phakic intraocular lenses are manufactured lenses that are surgically inserted in the eyes of patients to correct... | ['Anterior Chamber', 'Aqueous Humor', 'Humans', 'Hydrodynamics', 'Intraocular Pressure', 'Iris', 'Lens Implantation, Intraocular', 'Lenses, Intraocular', 'Mathematical Concepts', 'Models, Biological', 'Refractive Errors', 'Refractive Surgical Procedures'] | 28,992,107 | [['A09.371.060.067'], ['A09.371.060.067.070', 'A12.207.270.040'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.342'], ['G14.440'], ['A09.371.060.450', 'A09.371.894.513'], ['E04.540.825.600'], ['E07.632.500.460', 'E07.695.460'], ['G17'], ['E05.599.395'], ['C11.744'], ['E04.540.825']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of the alpha glucosidase inhibitor acarbose on endothelial function after a mixed meal in newly diagnosed type 2 diabetes. | Endothelial dysfunction (ED) has been suggested as a possible causal link between postprandial hyperglycemia and cardiovascular events in patients with type 2 diabetes. Recent trials demonstrated a reduction of cardiovascular events by treatment with alpha-glucosidase inhibitor acarbose - a drug which mainly reduces po... | ['Acarbose', 'Adult', 'Aged', 'Case-Control Studies', 'Diabetes Mellitus, Type 2', 'Double-Blind Method', 'Endothelium, Vascular', 'Enzyme Inhibitors', 'Fasting', 'Female', 'Glycoside Hydrolase Inhibitors', 'Humans', 'Male', 'Middle Aged', 'Postprandial Period', 'Regional Blood Flow'] | 19,061,152 | [['D09.698.629.802.100'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C18.452.394.750.149', 'C19.246.300'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['A07.015.700.500', 'A10.272.491.355'], ['D27.505.5... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Patient education and intrauterine contraception: a study of two package inserts. | In July 1975 the Food and Drug Administration proposed a patient information package insert for all women considering use of an intrauterine device. In the same year we also prepared a brochure to be given to women considering use of a specific intrauterine contraceptive, the PROGESTASERT system. To compare these infor... | ['Attitude', 'Female', 'Humans', 'Intrauterine Devices', 'Patient Education as Topic'] | 855,889 | [['F01.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.190.250.510'], ['I02.233.332.500', 'N02.421.726.407.680']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
[Cross correlation function of BAEP for objective assessment of hearing threshold]. | Brainstem auditory evoked potentials (BAEP) recorded were equally divided into two subensembles and a cross correlation function R (lambda) was calculated for them. The average amplitude of R (lambda) around lambda = 0 was chosen as the criterion for hearing threshold measurement. A linear regression equation which rep... | ['Auditory Threshold', 'Brain Stem', 'Evoked Potentials, Auditory', 'Humans', 'Mathematics', 'Regression Analysis'] | 2,762,846 | [['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['A08.186.211.132'], ['G07.265.216.500.370', 'G07.888.250', 'G11.561.200.500.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.548'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Clinical competence in pain assessment. | Our knowledge about the content of the clinical knowledge used by nurses in a surgical recovery unit for assessment of postoperative pain is fairly limited. The aim of the present study was to analyse and describe the variations of nurses' conceptions of the impact of clinical experience on competence in post-operative... | ['Adult', 'Attitude of Health Personnel', 'Clinical Competence', 'Critical Care', 'Diagnosis, Differential', 'Female', 'Health Knowledge, Attitudes, Practice', 'Hospitals, University', 'Humans', 'Male', 'Middle Aged', 'Nursing Assessment', 'Nursing Methodology Research', 'Nursing Staff, Hospital', 'Pain Measurement', '... | 11,000,601 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E02.760.190', 'N02.421.585.190'], ['E01.171'], ['F01.100.150.500', 'N05.300.150.410'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N04.590.23... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
The physiological ecology of the supratidal amphipod Talorchestia longicornis. | Physiology, behavior, habitat, and morphology are used to determine the degree of adaptation to life on land for amphipod species and systemization within the four functional groups of the family talitridae. Talorchestia longicornis is a semi-terrestrial amphipod found in the supratidal zone of estuaries. The present s... | ['Acclimatization', 'Aerobiosis', 'Amphipoda', 'Animals', 'Body Weight', 'Chlorides', 'Ecosystem', 'Hemolymph', 'Ions', 'Osmolar Concentration', 'Oxygen Consumption', 'Regression Analysis', 'Salinity', 'Sample Size', 'Time Factors', 'Water Movements', 'Water-Electrolyte Balance'] | 22,062,800 | [['G07.025.133', 'G16.012.500.133'], ['G02.111.017', 'G03.049'], ['B01.050.500.131.365.055'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D01.210.450.150', 'D01.248.497.158.215'], ['G16.500.275.157', 'N06.230.124'], ['A13.453'], ['D... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Arquivos de Neuro-Psiquiatria: 75 years. | This year marks the 75th year of publication of Arquivos de Neuro-Psiquiatria (ANP), the official journal of the Brazilian Academy of Neurology and one of the most important neuroscience journals in Latin America. ANP was initially edited by Oswaldo Lange, its founder, and subsequently by Antonio Spina-Fran?a Netto and... | ['Brazil', 'History, 20th Century', 'History, 21st Century', 'Neuropsychiatry', 'Periodicals as Topic'] | 29,364,394 | [['Z01.107.757.176'], ['K01.400.504.968'], ['K01.400.504.984'], ['F04.096.544.504', 'H02.403.690.754'], ['L01.178.682.829.678']] | ['Geographicals [Z]', 'Humanities [K]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 |
A novel drug delivery system of intraperitoneal chemotherapy for peritoneal carcinomatosis using gelatin microspheres incorporating cisplatin. | BACKGROUND: Peritoneal carcinomatosis is a poor prognostic factor for patients with gastrointestinal, gynecologic, and pancreatic cancer. Cisplatin (CDDP) is among the most effective anti-cancer agents, although its adverse effects remain unresolved. For the treatment of peritoneal carcinomatosis with high-dose CDDP, i... | ['Animals', 'Antineoplastic Agents', 'Carcinoma', 'Cisplatin', 'Drug Delivery Systems', 'Gelatin', 'Injections, Intraperitoneal', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Microspheres', 'Peritoneal Neoplasms', 'Tissue Distribution', 'Weight Loss'] | 24,008,088 | [['B01.050'], ['D27.505.954.248'], ['C04.557.470.200'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E02.319.300'], ['D12.776.860.476'], ['E02.319.267.530.490'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['E07.565'], ['C04.588.03... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enteritis associated with Campylobacter laridis. | Campylobacter laridis has occasionally been isolated from patients with diarrhea, but its clinical significance in this setting has yet to be established. We report a patient with a self-limited diarrheal illness whose stool cultures yielded C. laridis. The patient also developed a specific serum bactericidal antibody ... | ['Adult', 'Antibodies, Bacterial', 'Campylobacter', 'Campylobacter Infections', 'Diarrhea', 'Enteritis', 'Feces', 'Humans', 'Male'] | 3,793,864 | [['M01.060.116'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['B03.440.180', 'B03.660.150.235.250.500'], ['C01.150.252.400.177'], ['C23.888.821.214'], ['C06.405.205.462', 'C06.405.469.326'], ['A12.459'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of the cardiomyopathy-causing E244D mutation of troponin T on the structures of cardiac thin filaments studied by small-angle X-ray scattering. | Small-angle X-ray scattering experiments were carried out to investigate the structural changes of cardiac thin filaments induced by the cardiomyopathy-causing E244D mutation in troponin T (TnT). We examined native thin filaments (NTF) from a bovine heart, reconstituted thin filaments containing human cardiac wild-type... | ['Actin Cytoskeleton', 'Animals', 'Cardiomyopathies', 'Humans', 'Mutation', 'Tropomyosin', 'Troponin', 'Troponin T'] | 30,599,212 | [['A11.284.430.214.190.750.050'], ['B01.050'], ['C14.280.238'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590'], ['D05.750.078.730.800', 'D12.776.210.500.895', 'D12.776.220.525.800'], ['D05.500.945', 'D05.750.078.730.825', 'D12.776.210.500.910', 'D12.776.220.525.825'], ['D05.500.945.962', 'D05.750.078.... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mutagenicity of pyrolysates of salt-tolerant bacteria from food and cigarettes. | Smoke condensates obtained by pyrolysis of the cells of microorganisms isolated from food and cigarettes and of laboratory cultures were shown to be mutagenic to Salmonella typhimurium TA98 and TA100 in incorporation with liver microsomal fraction S-9 mix. The smoke condensates from salt-tolerant bacteria, which belong... | ['Bacteria', 'Drug Resistance', 'Food Microbiology', 'Mutagenicity Tests', 'Mutagens', 'Plants, Toxic', 'Salts', 'Smoke', 'Tobacco'] | 6,831,395 | [['B03'], ['G07.690.773.984'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['E05.393.560', 'E05.940.560'], ['D27.888.569.468'], ['B01.650.660'], ['D01.786'], ['D20.633.937'], ['B01.650.940.800.575.912.250.908.500.900']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Prevalence and characterization of methicillin-resistant Staphylococcus aureus carrying mecA or mecC and methicillin-susceptible Staphylococcus aureus in dairy sheep farms in central Italy. | Between January and May 2012, a total of 286 bulk tank milk samples from dairy sheep farms located in central Italy were tested for the presence of Staphylococcus aureus. One hundred fifty-three samples were positive for S. aureus (53.5%), with an average count of 2.53 log cfu/mL. A total of 679 S. aureus colonies were... | ['Animals', 'Anti-Bacterial Agents', 'Bacterial Proteins', 'Cefoxitin', 'Disk Diffusion Antimicrobial Tests', 'Farms', 'Genes, Bacterial', 'Italy', 'Methicillin', 'Methicillin-Resistant Staphylococcus aureus', 'Microbial Sensitivity Tests', 'Milk', 'Penicillin-Binding Proteins', 'Sheep', 'Staphylococcus aureus'] | 28,780,098 | [['B01.050'], ['D27.505.954.122.085'], ['D12.776.097'], ['D02.065.589.099.249.250.222', 'D02.886.665.074.250.222', 'D03.633.100.300.249.250.222'], ['E01.370.225.875.595.399', 'E05.200.875.595.399'], ['J01.040.372', 'J03.540.150'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Light-evoked current responses in rod bipolar cells, cone depolarizing bipolar cells and AII amacrine cells in dark-adapted mouse retina. | Light-evoked excitatory cation current (DeltaI(C)) and inhibitory chloride current (DeltaI(Cl)) of rod and cone depolarizing bipolar cells (DBC(R)s and DBC(C)s) and AII amacrine cells (AIIACs) in dark-adapted mouse retinal slices were studied by whole-cell voltage-clamp recording techniques, and the cell morphology was... | ['Amacrine Cells', 'Animals', 'Dark Adaptation', 'Darkness', 'In Vitro Techniques', 'Mice', 'Mice, Inbred C57BL', 'Photic Stimulation', 'Retinal Cone Photoreceptor Cells', 'Retinal Rod Photoreceptor Cells'] | 15,181,169 | [['A08.675.358.050', 'A08.675.650.850.500', 'A09.371.729.831.500', 'A11.671.358.050', 'A11.671.650.850.500'], ['B01.050'], ['G14.020.371'], ['G01.590.540.233'], ['E05.481'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['E05.723.729'], ... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Novel complex phenomena in ferroelectric nanocomposites. | A first-principles-based effective Hamiltonian is used to investigate finite-temperature properties of ferroelectric nanocomposites made of periodic arrays of ferroelectric nanowires embedded in a matrix formed by another ferroelectric material. Novel transitions and features related to flux-closure configurations are ... | ['Computer Simulation', 'Magnetite Nanoparticles', 'Models, Chemical', 'Models, Molecular', 'Molecular Conformation', 'Thermal Conductivity'] | 22,968,903 | [['L01.224.160'], ['J01.637.512.600.500.144.500'], ['E05.599.495'], ['E05.599.595'], ['G02.111.570.820'], ['G01.906.730']] | ['Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Antibody mimics based on human fibronectin type three domain engineered for thermostability and high-affinity binding to vascular endothelial growth factor receptor two. | The tenth human fibronectin type three domain ((10)Fn3) is a small (10 kDa), extremely stable and soluble protein with an immunoglobulin-like fold, but without cysteine residues. Selections from (10)Fn3-based libraries of proteins with randomized loops have yielded high-affinity, target-specific antibody mimics. Howeve... | ['Amino Acid Sequence', 'Antibodies', 'Fibronectins', 'Hot Temperature', 'Humans', 'Molecular Mimicry', 'Mutagenesis, Site-Directed', 'Protein Binding', 'Protein Denaturation', 'Protein Engineering', 'Solubility', 'Thermodynamics', 'Vascular Endothelial Growth Factor Receptor-2'] | 16,087,651 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
One-pot, exchange-free, room-temperature synthesis of sub-10 nm aqueous, noninteracting, and stable zwitterated iron oxide nanoparticles. | Stable aqueous dispersions of superparamagnetic iron oxide nanoparticles were synthesized in one step in the presence of a zwitterionic siloxane as the stabilizing/capping/solubilizing ligand. The hydrodynamic diameter of the particles was tuned by controlling the concentration of zwitterion siloxane, which ultimately ... | ['Ferric Compounds', 'Magnetite Nanoparticles', 'Particle Size', 'Surface Properties', 'Temperature', 'Water'] | 23,394,134 | [['D01.490.100'], ['J01.637.512.600.500.144.500'], ['G02.712'], ['G02.860'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Rapid detection of Salmonella spp. in food by use of the ISO-GRID hydrophobic grid membrane filter. | A rapid hydrophobic grid-membrane filter (HGMF) method was developed and compared with the Health Protection Branch cultural method for the detection of Salmonella spp. in 798 spiked samples and 265 naturally contaminated samples of food. With the HGMF method, Salmonella spp. were isolated from 618 of the spiked sample... | ['Filtration', 'Food Microbiology', 'Methods', 'Salmonella'] | 7,059,168 | [['E05.196.454', 'G01.280', 'G02.263'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['E05.581'], ['B03.440.450.425.800', 'B03.660.250.150.710']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Changes of the activity of certain lysosomal enzymes in the blood serum of whole-body irradiated rats. | The activities of acid phosphatase, beta-glucuronidase, beta-galactosidase, acid ribonuclease, and acid deoxyribonuclease were studied in the blood serum of rats after total, either single or franctionated, exposure. After the single, total exposure to 800 R of X-rays, remarkable increases in the activities of acid pho... | ['Acid Phosphatase', 'Animals', 'Cobalt Radioisotopes', 'Deoxyribonucleases', 'Endonucleases', 'Galactosidases', 'Gamma Rays', 'Glucuronidase', 'Male', 'Radiation Injuries, Experimental', 'Rats', 'Ribonucleases', 'X-Rays'] | 898,216 | [['D08.811.277.352.650.025'], ['B01.050'], ['D01.268.556.185.500.354', 'D01.268.956.155.500.354', 'D01.496.239.354', 'D01.496.749.256', 'D01.552.544.185.500.354'], ['D08.811.277.352.335'], ['D08.811.277.352.355'], ['D08.811.277.450.410'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['D08.811.277.450.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The shape of the transmembrane domain is a novel endocytosis signal for single-spanning membrane proteins. | Endocytosis is crucial for all cells as it allows them to incorporate material from the extracellular space and control the availability of transmembrane proteins at the plasma membrane. In yeast, endocytosis followed by recycling to the plasma membrane results in a polarised distribution of membrane proteins by a kine... | ['Amino Acid Sequence', 'Animals', 'CHO Cells', 'Cricetulus', 'Endocytosis', 'Endosomal Sorting Complexes Required for Transport', 'Membrane Proteins', 'Protein Domains', 'Protein Sorting Signals', 'Protein Transport', 'Qa-SNARE Proteins', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Ubiquitin-Prot... | 28,972,131 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['G04.417'], ['D05.500.199', 'D12.776.543.990.493'], ['D12.776.543'], ['G02.111.570.820.709.275.750', 'G02.111.570.820.709.610.500'], ['D12.644.770', 'G02.111.570.060.670'], ['G... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The feminization of poverty: myth or reality? | The feminization of poverty is a widely discussed concept in the mass media, and in academic circles, which captures the following facts: there are more poor women than poor men, and women are more likely to fall into poverty because of gender-related factors. In this article, I examine the concept's empirical basis an... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Employment', 'Female', 'Humans', 'Male', 'Middle Aged', 'Ownership', 'Poverty', 'Sex Factors', 'Social Class', 'Social Conditions', 'Socioeconomic Factors', 'United States', 'Women'] | 2,925,300 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['N01.824.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.880.604.583.594', 'N04.452.633'], ['I01.880.735.634', 'I01.880.853.996.535', 'N01.824.600'], ['N05.715.350.675', 'N06.850.490.875']... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Simultaneous determination of daphnetin, daphnoretin, daphneticin in rat plasma by LC-MS/MS and its application in pharmacokinetic study]. | To establish HPLC-MS/MS method for simultaneous determination of daphnetin, daphnoretin, and daphneticin in rat plasma after oral and intravenous administration of Daphne giraldii extract, and then use them in the calculation of pharmacokinetic parameters. Six sprague-dawley rats received intragastric administration of... | ['Animals', 'Chromatography, Liquid', 'Coumarins', 'Daphne', 'Plant Extracts', 'Rats', 'Rats, Sprague-Dawley', 'Tandem Mass Spectrometry', 'Umbelliferones'] | 29,090,558 | [['B01.050'], ['E05.196.181.400'], ['D03.383.663.283.446', 'D03.633.100.150.446'], ['B01.650.940.800.575.912.250.932.500'], ['D20.215.784.500', 'D26.667'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['E05.196.566.880'], ['D03.383.663.283.446.912', 'D03.633.100.150.446.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The efficacy of low-dose transdermal fentanyl in opioid-na?ve cancer patients with moderate-to-severe pain. | BACKGROUND/AIMS: Little is known about the efficacy of low-dose transdermal fentanyl (TDF) patches in opioid-na?ve patients with moderate-to-severe cancer pain.METHODS: This study had an open-label, prospective design, and was conducted between April 2007 and February 2009 in seven tertiary cancer hospitals; 98 patient... | ['Administration, Cutaneous', 'Adult', 'Aged', 'Aged, 80 and over', 'Analgesics, Opioid', 'Female', 'Fentanyl', 'Humans', 'Intention to Treat Analysis', 'Male', 'Middle Aged', 'Neoplasms', 'Pain', 'Pain Measurement', 'Prospective Studies', 'Republic of Korea', 'Severity of Illness Index', 'Tertiary Care Centers', 'Time... | 25,589,840 | [['E02.319.267.120.060'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['D03.383.621.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.250.250.365.500.500',... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Modeling relations in nature and eco-informatics: a practical application of rosennean complexity. | The purpose of eco-informatics is to communicate critical information about organisms and ecosystems. To accomplish this, it must reflect the complexity of natural systems. Present information systems are designed around mechanistic concepts that do not capture complexity. Robert Rosen's relational theory offers a way ... | ['Ecosystem', 'Information Management', 'Models, Theoretical', 'Nature'] | 17,955,469 | [['G16.500.275.157', 'N06.230.124'], ['L01.399'], ['E05.599'], ['K01.637']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Idiopathic uric acid lithiasis: epidemiologic and metabolic aspects. | Of 264 patients with urolithiasis those with pure uric acid or urate stones were compared to those with other types of calculi for differences in epidemiologic factors and uric acid, calcium and phosphate metabolism. Patients with uric acid stones were predominantly older men. These patients had comparatively lower inc... | ['Age Factors', 'Alcohol Drinking', 'Calcium Oxalate', 'Calcium Phosphates', 'Female', 'Gout', 'Humans', 'Hydrogen-Ion Concentration', 'Male', 'Middle Aged', 'Phosphates', 'Purines', 'Socioeconomic Factors', 'Uric Acid', 'Urinary Calculi', 'Urine'] | 7,154,174 | [['N05.715.350.075', 'N06.850.490.250'], ['F01.145.317.269'], ['D02.241.081.337.593.750.500'], ['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['C05.550.114.423', 'C05.550.354.500', 'C05.799.414', 'C16.320.565.798.368', 'C18.452.648.798.368'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Impact of 6-year body weight change on cardiac geometry and function in ageing adults: the SUppl?mentation en Vitamines et Min?raux AntioXydants -2 (SU.VI.MAX-2) cardiovascular ultrasound substudy. | BACKGROUND AND OBJECTIVE: Although the relationships between BMI and cardiac geometry and function have been established, information remains limited on the impact of BMI, waist circumference and body composition variations over time on echocardiographic changes in ageing adults.METHODS AND RESULTS: Multiple linear reg... | ['Aging', 'Antioxidants', 'Body Composition', 'Body Mass Index', 'Body Weight', 'Cardiovascular Diseases', 'Cohort Studies', 'Dietary Supplements', 'Echocardiography', 'Female', 'Heart', 'Humans', 'Linear Models', 'Male', 'Ultrasonics', 'Vitamins'] | 20,706,135 | [['G07.345.124'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Sirolimus and paclitaxel provoke different vascular pathological responses after local delivery in a murine model for restenosis on underlying atherosclerotic arteries. | BACKGROUND: Drug-eluting stents (DES) have been introduced successfully in clinical practice to prevent post-angioplasty restenosis. Nevertheless, concerns about the safety of DES still exist.OBJECTIVE: To investigate the vascular pathology and transcriptional responses to sirolimus and paclitaxel in a murine model for... | ['Actins', 'Animals', 'Apoptosis', 'Atherosclerosis', 'Cell Proliferation', 'Collagen', 'Drug Implants', 'Femoral Artery', 'Image Interpretation, Computer-Assisted', 'In Situ Nick-End Labeling', 'Male', 'Mice', 'Mice, Mutant Strains', 'Models, Animal', 'Muscle, Smooth, Vascular', 'Paclitaxel', 'RNA, Messenger', 'Recurr... | 17,449,502 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['G04.146.954.035'], ['C14.907.137.126.307'], ['G04.161.750', 'G07.345.249.410.750'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D26.255.210.315'], ['A07.015.114.351'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Incidence of falling injuries leading to medical treatment in the elderly. | The incidence of falling injuries leading to medical treatment was described by sex, age, marital status, education, amount of daily motion, self-perceived health, mechanism of fall and severity of injury. Material was collected regarding persons aged 65 years or over seeking medical treatment due to a fall during a pe... | ['Accidental Falls', 'Accidents, Home', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Female', 'Finland', 'Frail Elderly', 'Home Care Services', 'Humans', 'Incidence', 'Male', 'Sex Factors', 'Trauma Severity Indices', 'Wounds and Injuries'] | 1,754,661 | [['N06.850.135.122'], ['N06.850.135.217'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.542.816.186'], ['M01.060.116.100.540'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.... | ['Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Attenuation of the haemodynamic responses to noxious stimuli in patients undergoing cataract surgery. A comparison of magnesium sulphate, esmolol, lignocaine, nitroglycerine and placebo given i.v. with induction of anaesthesia. | A study was conducted on 100 middle-aged to elderly patients (n = 52, healthy; n = 48, suffering from either diabetes, hypertension, ischaemic heart disease or a combination of these diseases) undergoing cataract extraction to assess the effects of laryngoscopy and tracheal intubation, anaesthesia and surgery, eye band... | ['Adrenergic beta-Antagonists', 'Aged', 'Anesthesia', 'Anesthetics, Local', 'Blood Pressure', 'Cataract Extraction', 'Female', 'Heart Rate', 'Hemodynamics', 'Humans', 'Injections, Intravenous', 'Intraoperative Complications', 'Intubation, Intratracheal', 'Lidocaine', 'Magnesium Sulfate', 'Male', 'Middle Aged', 'Nitrogl... | 9,088,811 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116.100'], ['E03.155'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E04.540.825.249'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G09.330.380'], ['B01.05... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Interaction of Aspergillus flavus and A. parasiticus with Salmonella spp. isolated from peanuts. | Although Aspergillus flavus and Aspergillus parasiticus are the main microorganisms of concern in peanuts, due to aflatoxin contamination, several Salmonella outbreaks from this product have been reported over the last ten decades. Thus, it is important to understand the relationship between microorganisms to predict, ... | ['Aflatoxin B1', 'Aflatoxins', 'Antibiosis', 'Arachis', 'Aspergillus flavus', 'Food Contamination', 'Food Microbiology', 'Salmonella'] | 32,454,365 | [['D03.383.663.283.119.075', 'D03.633.100.150.119.075', 'D23.946.587.142.075'], ['D03.383.663.283.119', 'D03.633.100.150.119', 'D23.946.587.142'], ['G06.550.050', 'G16.062'], ['B01.650.940.800.575.912.250.401.077'], ['B01.300.381.081.170'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['H0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
[Acceptability of the HPV vaccine among Spanish university students in the pre-vaccine era: a cross-sectional study]. | INTRODUCTION: Cervical cancer (CC), the second most common cause of cancer deaths in women, is associated with the infection of human papillomavirus (HPV) and is more prevalent in women between the ages of 20 and 24. This research is aimed to determine the background about CC, the human papillomavirus infection and its... | ['Age Factors', 'Attitude', 'Cross-Sectional Studies', 'Data Collection', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Papillomavirus Infections', 'Papillomavirus Vaccines', 'Patient Acceptance of Health Care', 'Sex Factors', 'Spain', 'Students', 'Surveys and Questionnaires', 'Universities', 'V... | 25,690,141 | [['N05.715.350.075', 'N06.850.490.250'], ['F01.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.925.256.650', 'C01.925... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Te... | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
The mechanical effects of intervertebral disc lesions. | OBJECTIVE: To determine the mechanical effect of individual concentric tears, radial tears and rim lesions of the intervertebral disc anulus.DESIGN: In vitro dynamic mechanical testing of sheep discs comparing the mechanical behaviour before and after lesion creation.BACKGROUND: Structural changes to the disc in the fo... | ['Aging', 'Animals', 'Biomechanical Phenomena', 'Female', 'In Vitro Techniques', 'Intervertebral Disc', 'Intervertebral Disc Displacement', 'Lumbar Vertebrae', 'Physical Stimulation', 'Range of Motion, Articular', 'Sheep', 'Torque'] | 15,182,979 | [['G07.345.124'], ['B01.050'], ['G01.154.090', 'G01.374.089'], ['E05.481'], ['A02.165.308.410', 'A02.835.232.834.432', 'A10.165.382.350.050'], ['C05.116.900.307', 'C23.300.707.952'], ['A02.835.232.834.519'], ['E05.723'], ['E01.370.600.700', 'G11.427.760'], ['B01.050.150.900.649.313.500.380.791'], ['G01.374.860.500']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genomics of experimental adaptation of Staphylococcus aureus to a natural combination of insect antimicrobial peptides. | Antimicrobial peptides (AMP) are highly conserved immune effectors across the tree of life and are employed as combinations. In the beetle Tenebrio molitor, a defensin and a coleoptericin are highly expressed in vivo after inoculation with S. aureus. The defensin displays strong in vitro activity but no survival benefi... | ['Acclimatization', 'Animals', 'Anti-Bacterial Agents', 'Antimicrobial Cationic Peptides', 'Bacterial Proteins', 'Defensins', 'Drug Resistance, Multiple, Bacterial', 'Genomics', 'Insect Proteins', 'Microbial Sensitivity Tests', 'Staphylococcal Infections', 'Staphylococcus aureus', 'Tenebrio'] | 30,337,550 | [['G07.025.133', 'G16.012.500.133'], ['B01.050'], ['D27.505.954.122.085'], ['D12.644.050', 'D12.776.543.695.054'], ['D12.776.097'], ['D12.644.050.200', 'D12.776.543.695.054.200'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['H01.158.273.180.350', 'H01.158.273.343.3... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A survey of patients leaving a mental hospital against medical advice. | A consecutive series of 100 male psychiatric patients who requested release against medical advice during an 11-month period was compared with a control group consisting of a random sample of 100 patients admitted during the same period who did not submit such a request. The majority of those who submitted the request ... | ['Age Factors', 'Aggression', 'Alcoholism', 'Chronic Disease', 'Family Characteristics', 'Female', 'Hospitalization', 'Hospitals, Psychiatric', 'Humans', 'Length of Stay', 'Male', 'Motivation', 'Patient Readmission', 'Schizophrenia'] | 1,033,140 | [['N05.715.350.075', 'N06.850.490.250'], ['F01.145.126.125', 'F01.145.813.045'], ['C25.775.100.250', 'F03.900.100.350'], ['C23.550.291.500'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['E02.760.400', 'N02.421.585.400'], ['N02.278.421.556.508'], ['B01... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Chromosome anomalies in early human embryos. | A study of the chromosome constitution of an unselected group of human preimplantation embryos fertilized in vitro showed that, of 30 studied, 7 (23%) were abnormal: 6 were aneuploid, half being trisomic and half monosomic. If the increased maternal age of the oocyte donors and the lethality of autosomal monosomy is ta... | ['Adult', 'Blastocyst', 'Chromosome Aberrations', 'Female', 'Fertilization in Vitro', 'Humans', 'Karyotyping', 'Maternal Age'] | 3,193,408 | [['M01.060.116'], ['A16.254.500'], ['C23.550.210', 'G05.365.590.175'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['G08.686.560', 'N05.715.350.075.550', 'N06.850.490.250.550']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Antioxidative effects of flavonoids and their metabolites against hypoxia/reoxygenation-induced oxidative stress in a human first trimester trophoblast cell line. | This study aimed to investigate the cytoprotective effects of flavonoids, their metabolites alone or in combination against hypoxia/reoxygenation induced oxidative stress in the transformed human first trimester trophoblast cell line (HTR-8/SVneo). Oxidative stress was achieved with hypoxia followed by reoxygenation an... | ['Antioxidants', 'Cell Hypoxia', 'Cell Line', 'Female', 'Flavonoids', 'Humans', 'Hydrogen Peroxide', 'Oxidative Stress', 'Oxygen', 'Pregnancy', 'Pregnancy Trimester, First', 'Trophoblasts'] | 30,309,520 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G03.197.300', 'G04.270.300'], ['A11.251.210'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['G0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prostanoid modulation of glucose transport in isolated diabetic rat uterus. | 3-O-14C-methyl-D-Glucose (3-O-MG) transport and 14C-saccharose incorporation were measured in isolated uterine strips from ovariectomized-estrogenized diabetic rats. Glucose transport was decreased in uterine strips from diabetic rats compared with control animals. PGE1 and PGE2 (10(-7) M) stimulated 3-O-MG transport, ... | ['3-O-Methylglucose', 'Alprostadil', 'Animals', 'Biological Transport', 'Diabetes Mellitus, Experimental', 'Dinoprost', 'Dinoprostone', 'Drug Interactions', 'Female', 'In Vitro Techniques', 'Insulin', 'Ovariectomy', 'Rats', 'Rats, Wistar', 'Streptozocin', 'Sucrose', 'Thromboxane B2', 'Up-Regulation', 'Uterus'] | 8,804,128 | [['D09.408.348.500.500', 'D09.408.514.622.500'], ['D10.251.355.255.550.250.100', 'D10.251.355.325.050', 'D23.469.050.175.725.250.100'], ['B01.050'], ['G03.143'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D10.251.355.255.550.400.200', 'D23.469.050.175.725.400.200'], ['D10.251.355.255.550.250.200', 'D2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recurrent germline mutations in BRCA1 and BRCA2 genes in high risk families in Israel. | The spectrum of germline mutations among Jewish non Ashkenazi high risk breast/ovarian cancer families includes a few predominant mutations in BRCA1 (185delAG and Tyr978X) and BRCA2 (8765delAG). A few additional recurring mutations [A1708E, 981delAT, C61G (BRCA1) R2336P, and IVS2 + 1G > A (BRCA2)] have been reported in... | ['Adult', 'Aged', 'Ethnic Groups', 'Female', 'Genes, BRCA1', 'Genes, BRCA2', 'Germ-Line Mutation', 'Humans', 'Israel', 'Jews', 'Male', 'Middle Aged', 'Neoplasms'] | 22,399,190 | [['M01.060.116'], ['M01.060.116.100'], ['M01.686.754', 'N01.224.317'], ['G05.360.340.024.340.375.249.100', 'G05.360.340.024.340.415.400.100'], ['G05.360.340.024.340.375.249.105', 'G05.360.340.024.340.415.400.105'], ['G05.365.590.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.375'], ['M01.686.... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Variants of plastic operations on the anterior wall of the frontal sinus]. | Variants of plastic reconstruction of the frontal sinus anterior wall in its traumatic lesion is reviewed. Examination and treatment of 17 patients with the diagnosis of fracture of the frontal sinus anterior wall with a cosmetic defect were performed in Moscow hospital N 1. Plastic reconstruction consisted of repositi... | ['Frontal Sinus', 'Humans', 'Rhinoplasty'] | 17,495,803 | [['A04.531.621.387'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.218.755', 'E04.580.392.500', 'E04.680.650']] | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Risk assessment for pressure ulcers: an adaptation of the National Pressure Ulcer Advisory Panel risk factors to spinal cord injured patients. | To estimate risk factors for pressure ulcers, we developed quantitative definitions for each of the nine general areas of risk outlined by the 1989 National Pressure Ulcer Advisory Panel (NPUAP) and evaluated each of these factors in a group of spinal cord injured patients by means of a retrospective chart review at a ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pressure Ulcer', 'Risk Factors', 'Spinal Cord Injuries'] | 8,366,340 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C17.800.893.665'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['C10.228.854.763', 'C10.900... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of phospholipases on factor-VIII activity. | The effect of the enzymes phospholipases C and D on Factor VIII were investigated. Phospholipase D was found to activate the partially purified intact Factor-VIII molecule maximally at a final concentration of 0.6 U/ml. Neither the dissociated small molecular weight component nor the high molecular weight component wer... | ['Factor VIII', 'Hemophilia A', 'Humans', 'Molecular Weight', 'Phospholipases', 'Protein Conformation', 'von Willebrand Diseases'] | 304,830 | [['D12.776.124.125.350', 'D12.776.811.286', 'D23.119.350'], ['C15.378.100.100.500', 'C15.378.100.141.500', 'C15.378.463.500', 'C16.320.099.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.494'], ['D08.811.277.352.100.680', 'D08.811.277.352.640.700'], ['G02.111.570.820.709'], ['C15.378.100.100.900', 'C15.37... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sensitivity to change of 3 Systemic Lupus Erythematosus Disease Activity Indices: international validation. | OBJECTIVE: Three indices, the SLE Disease Activity Index (SLEDAI), the Systemic Lupus Activity Measure (SLAM) and the British Isles Lupus Assessment Group (BILAG), have been found to be reliable and valid measures of disease activity in patients with systemic lupus erythematosus (SLE). Our aim was to investigate their ... | ['Computers', 'Humans', 'Lupus Erythematosus, Systemic', 'Retrospective Studies', 'Sensitivity and Specificity', 'Severity of Illness Index'] | 7,983,648 | [['L01.224.230.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.300.480', 'C20.111.590'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ['E05.318.370.800', 'E05.318.740.872'... | ['Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Transfer to High-Volume Centers Associated With Reduced Mortality After Endovascular Treatment of Acute Stroke. | BACKGROUND AND PURPOSE: Some have argued that it may be beneficial to expand the availability of endovascular revascularization services to lower-volume hospitals to minimize the morbidity associated with transfer to larger endovascular centers. We compared the outcomes after revascularization of patients directly admi... | ['Aged', 'Aged, 80 and over', 'Female', 'Hospital Mortality', 'Hospitals, High-Volume', 'Hospitals, Low-Volume', 'Humans', 'Male', 'Middle Aged', 'Outcome and Process Assessment, Health Care', 'Patient Transfer', 'Stroke'] | 28,336,679 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['N02.278.421.414'], ['N02.278.421.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N04.761.559', 'N05.715.360.575'], ['E02.760.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[A comparative double blind study of lenampicillin and talampicillin in the treatment of oral infections]. | A comparative double blind study of lenampicillin (LAPC, KBT-1585) and talampicillin (TAPC) was carried out in order to objectively evaluate efficacy, safety and utility of LAPC in treatment of 238 patients with oral infections. Cases accepted by the Central Committee for evaluation of efficacy and utility were 218, co... | ['Adolescent', 'Adult', 'Aged', 'Ampicillin', 'Bacteria, Aerobic', 'Bacterial Infections', 'Clinical Trials as Topic', 'Double-Blind Method', 'Female', 'Gram-Negative Bacteria', 'Humans', 'Jaw Diseases', 'Male', 'Middle Aged', 'Mouth Diseases', 'Penicillin Resistance', 'Periodontitis', 'Talampicillin'] | 3,908,737 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['B03.120'], ['C01.150.252'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Objective accommodative amplitude and dynamics with the 1CU accommodative intraocular lens. | PURPOSE: To compare the objective accommodative amplitude and dynamics of eyes implanted with the one-compartment-unit (1CU; HumanOptics AG, Erlangen, Germany) accommodative intraocular lenses (IOLs) with that measured subjectively.METHODS: Twenty eyes with a 1CU accommodative IOL implanted were refracted and distance ... | ['Accommodation, Ocular', 'Adult', 'Aged', 'Female', 'Humans', 'Lens Implantation, Intraocular', 'Lenses, Intraocular', 'Male', 'Middle Aged', 'Phacoemulsification', 'Refraction, Ocular', 'Visual Acuity'] | 16,505,063 | [['G14.010'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.540.825.600'], ['E07.632.500.460', 'E07.695.460'], ['M01.060.116.630'], ['E04.540.825.249.704', 'E04.943.875'], ['E01.370.380.850.700', 'G01.590.775', 'G14.760'], ['E01.370.380.850.950', 'F02.463.593.932.901', 'G1... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pravastatin treatment of very low density, intermediate density and low density lipoproteins in hypercholesterolemia and combined hyperlipidemia secondary to the nephrotic syndrome. | BACKGROUND/AIMS: In the current study pravastatin was used in nephrotic syndrome patients with hypercholesterolemia and combined hyperlipidemia to test whether the drug decreases production of LDL and reduces levels of VLDL and IDL.METHODS: Thirteen patients (7 with high LDL alone and 6 with high VLDL, IDL and LDL) wer... | ['Anticholesteremic Agents', 'Cholesterol', 'Cholesterol, LDL', 'Cholesterol, VLDL', 'Cross-Over Studies', 'Female', 'Humans', 'Hypercholesterolemia', 'Hyperlipidemia, Familial Combined', 'Lipoproteins', 'Male', 'Nephrotic Syndrome', 'Pravastatin'] | 10,644,862 | [['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['D04.210.500.247.808.197.247', 'D10.532.599.700', 'D10.570.938.208.285', 'D12.776.521.622... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A country-wide malaria survey in Mozambique. II. Malaria attributable proportion of fever and establishment of malaria case definition in children across different epidemiological settings. | BACKGROUND: Protection against clinical malaria episodes is acquired slowly after frequent exposure to malaria parasites. This is reflected by a decrease with increasing age in both parasite density and incidence of clinical episodes. In many settings of stable malaria transmission, the presence of asymptomatic malaria... | ['Age Distribution', 'Animals', 'Blood', 'Body Temperature', 'Child', 'Child, Preschool', 'Confidence Intervals', 'Female', 'Fever', 'Humans', 'Incidence', 'Infant', 'Logistic Models', 'Malaria, Falciparum', 'Male', 'Mozambique', 'Parasitemia', 'Plasmodium falciparum', 'Prevalence', 'Risk Factors', 'Sensitivity and Spe... | 19,383,126 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['B01.050'], ['A12.207.152', 'A15.145'], ['E01.370.600.875.374', 'G07.110'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.30... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Prenatal exposure to air pollution and intergenerational economic mobility: Evidence from U.S. county birth cohorts. | New estimates reveal intergenerational economic mobility varies substantially across U.S. counties. The potential role of local environmental health exposures in structuring mobility outcomes has been thus far unexamined, despite mounting evidence that early life exposure to environmental pollutants has lasting impacts... | ['Adult', 'Air Pollutants', 'Cohort Studies', 'Economics', 'Environmental Exposure', 'Female', 'Humans', 'Income', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Social Mobility', 'United States'] | 30,296,695 | [['M01.060.116'], ['D27.888.284.101'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['I01.261', 'N03.219'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ['G08.686.784.769'], ['C13.703.824.500'], ['I01.880.853.996.755.673', 'N01.824.782.673'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Ovarian suppression reduces clinical and endocrine expression of late-onset congenital adrenal hyperplasia due to 21-hydroxylase deficiency. | OBJECTIVE: To determine the effectiveness of GnRH-agonist (GnRH-a) treatment in women with late onset congenital adrenal hyperplasia.DESIGN: Prospective assessment of GnRH-a treatment in six women with documented late-on-set congenital adrenal hyperplasia who were not preselected. Comparisons were made to previous resp... | ['17-alpha-Hydroxyprogesterone', 'Adolescent', 'Adrenal Hyperplasia, Congenital', 'Adult', 'Age of Onset', 'Androgens', 'Dexamethasone', 'Endocrine Glands', 'Female', 'Gonadotropins', 'Hirsutism', 'Humans', 'Hydroxyprogesterones', 'Ovary', 'Prospective Studies', 'Triptorelin Pamoate'] | 7,926,082 | [['D04.210.500.745.745.654.829.395.400', 'D06.472.334.851.687.750.478.400'], ['M01.060.057'], ['C12.706.316.090.500', 'C13.351.875.253.090.500', 'C16.131.939.316.129.500', 'C16.320.033', 'C16.320.565.925.249', 'C18.452.648.925.249', 'C19.053.440', 'C19.391.119.090.500'], ['M01.060.116'], ['N05.715.350.075.100', 'N06.85... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Isolation and characterization of PEP5, a gene essential for vacuolar biogenesis in Saccharomyces cerevisiae. | pep5 mutants of Saccharomyces cerevisiae accumulate inactive precursors to the vacuolar hydrolases. The PEP5 gene was isolated from a genomic DNA library by complementation of the pep5-8 mutation. Deletion analysis localized the complementing activity to a 3.3-kb DNA fragment. DNA sequence analysis of the PEP5 gene rev... | ['Alkaline Phosphatase', 'Amino Acid Sequence', 'Base Sequence', 'Codon', 'Fungal Proteins', 'Genes, Fungal', 'Genetic Complementation Test', 'Hydrolases', 'Immunoblotting', 'Microscopy, Electron', 'Molecular Sequence Data', 'Mutation', 'Plasmids', 'Restriction Mapping', 'Saccharomyces cerevisiae', 'Saccharomyces cerev... | 2,204,580 | [['D08.811.277.352.650.035'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D12.776.354'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['E05.39... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Biological studies on the main fractions of hematoporphyrin derivative. | The four main fractions of hematoporphyrin derivative were separated by high-pressure liquid chromatography. Each fraction was studied with respect to photosensitizing capabilities, fluorescence, and tumor tissue uptake in mice bearing EMT-6 tumors. Animals received i.p. injections of 10 mg/kg of each fraction, and 24 ... | ['Animals', 'Chromatography, High Pressure Liquid', 'Hematoporphyrin Derivative', 'Hematoporphyrins', 'Mice', 'Microscopy, Fluorescence', 'Neoplasms, Experimental', 'Radiation-Sensitizing Agents'] | 2,948,636 | [['B01.050'], ['E05.196.181.400.300'], ['D03.383.129.578.840.500.462.400', 'D03.633.400.909.500.462.400', 'D04.345.783.500.462.400', 'D23.767.727.462.400'], ['D03.383.129.578.840.500.462', 'D03.633.400.909.500.462', 'D04.345.783.500.462', 'D23.767.727.462'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.51... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Results of split liver transplantation in children. | OBJECTIVE: To analyze the outcome of 80 consecutive pediatric split liver transplants performed at the authors' center between 1994 and 2000.SUMMARY BACKGROUND DATA: Split liver transplantation has become an accepted method of increasing the number of available grafts for pediatric liver transplant recipients.METHODS: ... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Graft Survival', 'Humans', 'Infant', 'Infant, Newborn', 'Liver Failure', 'Liver Transplantation', 'Male', 'Postoperative Complications', 'Survival Analysis', 'Treatment Outcome'] | 12,170,031 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C06.552.308.500'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['C23.550.767'], ['E05.318.740.998', 'N05.715.360.750.795... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of murine recombinant interleukin-5 on bronchial reactivity in guinea-pigs. | We have reported that an intratracheal injection of murine recombinant interleukin-5 (mrIL-5, 15 micrograms/0.25 ml/animal) induces the increased number of inflammatory leucocytes and epithelial cells in bronchoalveolar lavage fluid (BALF) 24 hr after administration of mrIL-5 in guinea-pigs [1]. In this paper, we have ... | ['Animals', 'Bronchial Hyperreactivity', 'Cromolyn Sodium', 'Eosinophilia', 'Guinea Pigs', 'Interleukin-5', 'Ketotifen', 'Leukocyte Count', 'Male', 'Mice', 'Neutrophils', 'Prednisolone', 'Recombinant Proteins'] | 8,439,818 | [['B01.050'], ['C08.127.210'], ['D03.383.663.283.266.300', 'D03.633.100.150.266.300'], ['C15.378.553.231'], ['B01.050.150.900.649.313.992.550'], ['D12.644.276.374.465.202', 'D12.776.467.374.465.186', 'D23.529.374.465.202'], ['D02.886.778.370', 'D03.383.621.370', 'D03.383.903.370'], ['E01.370.225.500.195.107.595', 'E01.... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulator of G-protein signaling 4: A novel tumor suppressor with prognostic significance in non-small cell lung cancer. | Regulator of G-protein signaling (RGS) family members are regulatory molecules which act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. Emerging data indicated that RGS members were involved with tumorigenesis and metastasis. In the current study, we identified RGS4 as a novel t... | ['Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Carcinoma, Non-Small-Cell Lung', 'China', 'Female', 'Humans', 'Incidence', 'Lung Neoplasms', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Prognosis', 'RGS Proteins', 'Reproducibility of Results', 'Risk Factors', 'Sensitivity and Specificity', 'Survival Rate', 'Tumo... | 26,640,232 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of malonyl-CoA on the kinetics and substrate cooperativity of membrane-bound carnitine palmitoyltransferase of rat heart mitochondria. | The effect of malonyl-CoA on the kinetic parameters of carnitine palmitoyltransferase (outer) the outer form of carnitine palmitoyltransferase (palmitoyl-CoA: L-carnitine O-palmitoyltransferase, EC 2.3.1.21) from rat heart mitochondria was investigated using a kinetic analyzer in the absence of bovine serum albumin wit... | ['Acyl Coenzyme A', 'Acyltransferases', 'Animals', 'Carnitine', 'Carnitine O-Palmitoyltransferase', 'Fasting', 'Kinetics', 'Malonyl Coenzyme A', 'Membranes', 'Mitochondria, Heart', 'Mitochondrial Swelling', 'Rats', 'Substrate Specificity'] | 3,689,805 | [['D03.633.100.759.646.138.382.300', 'D08.211.211.300', 'D13.695.667.138.382.300', 'D13.695.827.068.382.300'], ['D08.811.913.050'], ['B01.050'], ['D02.092.877.883.099'], ['D08.811.913.050.350.200'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['G01.374.661', 'G02.111.490'], ['D03.633.100.759.646.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dicot-specific ATG8-interacting ATI3 proteins interact with conserved UBAC2 proteins and play critical roles in plant stress responses. | Selective macroautophagy/autophagy targets specific cargo by autophagy receptors through interaction with ATG8 (autophagy-related protein 8)/MAP1LC3 (microtubule associated protein 1 light chain 3) for degradation in the vacuole. Here, we report the identification and characterization of 3 related ATG8-interacting prot... | ['Arabidopsis', 'Autophagosomes', 'Autophagy', 'Autophagy-Related Protein 8 Family', 'Autophagy-Related Proteins', 'Carrier Proteins', 'Endoplasmic Reticulum', 'Humans', 'Microtubule-Associated Proteins', 'Plants', 'Stress, Physiological', 'Ubiquitin-Activating Enzymes', 'Vacuoles'] | 29,313,416 | [['B01.650.940.800.575.912.250.157.100'], ['A11.284.430.214.190.875.190.700.500'], ['G04.011'], ['D12.776.094.407', 'D12.776.220.600.450.100', 'D12.776.947.187'], ['D12.776.094'], ['D12.776.157'], ['A11.284.430.214.190.875.248'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.220.600.450', 'D12.776.631.560'... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A cardiovascular prescreening protocol for unmonitored in-office laryngology procedures. | OBJECTIVES: Currently, there are no cardiovascular (CV) preprocedure screening parameters for patients undergoing in-office laryngeal procedures (IOLP). Studies have shown significant changes in CV measures for IOLP. The aim was to develop and evaluate a pre-IOLP CV screening protocol.METHODS: Review of IOLP literature... | ['Adult', 'Aged', 'Aged, 80 and over', 'Blood Pressure', 'Cardiovascular Diseases', 'Clinical Protocols', 'Female', 'Heart Rate', 'Hemodynamics', 'Humans', 'Hypertension', 'Laryngoscopy', 'Male', 'Middle Aged', 'Office Visits', 'Patient Selection', 'Preoperative Care', 'Prospective Studies', 'Risk Assessment', 'Tachyca... | 28,407,258 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14'], ['E02.183', 'N05.715.360.330.125'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E01.370.386.460', 'E01.370.388.250.525... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The New Modern Mediterranean Diet Italian Pyramid. | BACKGROUND: Epidemiological studies have established the health benefits associated with the adherence to the MD (Mediterranean Diet), mainly in relation to reducing the risk of developing the non communicable diseases. The MD is a sustainable diet model that respects the environment, promotes the bio-diversity, the lo... | ['Diet, Healthy', 'Diet, Mediterranean', 'Feeding Behavior', 'Guidelines as Topic', 'Health Behavior', 'Health Promotion', 'Humans', 'Italy', 'Life Style', 'Nutritional Requirements', 'Obesity'] | 27,297,194 | [['F01.829.458.205.500', 'G07.203.650.240.629'], ['E02.642.249.270', 'G07.203.650.240.270'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['N04.761.700.350', 'N05.700.350'], ['F01.145.488'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['F01.829... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Spinal cord lesions and atrophy in NMOSD with AQP4-IgG and MOG-IgG associated autoimmunity. | BACKGROUND: Spinal cord (SC) affection is a hallmark symptom of neuromyelitis optica spectrum disorders (NMOSD). Patients with aquaporin-4 (AQP4-IgG+) or myelin oligodendrocyte glycoprotein (MOG-IgG+) antibody seropositivity show this overlapping clinical phenotype.OBJECTIVE: Quantitative comparison of SC lesions and a... | ['Adult', 'Aquaporin 4', 'Atrophy', 'Autoimmunity', 'Cross-Sectional Studies', 'Disability Evaluation', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Myelin-Oligodendrocyte Glycoprotein', 'Neuromyelitis Optica', 'Spinal Cord'] | 30,475,082 | [['M01.060.116'], ['D12.776.157.530.400.500.040.468', 'D12.776.543.550.450.730.040.468', 'D12.776.543.585.400.730.040.577'], ['C23.300.070'], ['G12.450.192'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.82... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gastrobronchial fistula. | Gastrobronchial fistula is an extremely rare condition. Trauma, subphrenic abscess and gastro-oesophageal surgery are the most commonly reported causes. We describe a case of gastrobronchial fistula occurring due to a peptic ulcer within a hiatus hernia six years following fundoplication. | ['Bronchial Fistula', 'Female', 'Gastric Fistula', 'Hernia, Hiatal', 'Humans', 'Middle Aged', 'Stomach Ulcer'] | 2,306,917 | [['C08.127.196', 'C08.702.196', 'C23.300.575.687.225'], ['C06.267.375', 'C23.300.575.185.375'], ['C23.300.707.960.500.467'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C06.405.469.275.800.849', 'C06.405.748.586.849']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Short-term exogenous glucocorticosteroidal effect on iron and copper status in canine leishmaniasis (Leishmania infantum). | Prednisolone was administered as an anti-inflammatory for 7 consecutive days in 11 dogs with leishmaniasis (CL group) and 5 clinically normal dogs (control group). After a 15-day wash-out phase, the same medication was given as an immunosuppressive for another 7-day period. In both animal groups and experimental period... | ['Animals', 'Blood Chemical Analysis', 'Copper', 'Dog Diseases', 'Dogs', 'Female', 'Glucocorticoids', 'Hematocrit', 'Hemoglobins', 'Iron', 'Leishmania infantum', 'Leishmaniasis, Visceral', 'Male', 'Prednisolone', 'Random Allocation'] | 16,479,727 | [['B01.050'], ['E01.370.225.124.100', 'E05.200.124.100'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['D12.776.124.400', 'D12.776.422.3... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Inhibition and object relations in borderline personality traits after traumatic brain injury. | This study aims to assess the nature and severity of borderline traits after traumatic brain injury (TBI). Thirty subjects with moderate or severe TBI were compared to 30 normal controls on the Revised Diagnostic Interview for Borderlines (DIB-R), a dimensional measure of borderline traits, the Go-no go inhibition task... | ['Adult', 'Borderline Personality Disorder', 'Brain Injuries', 'Case-Control Studies', 'Cognition Disorders', 'Disruptive, Impulse Control, and Conduct Disorders', 'Female', 'Humans', 'Inhibition, Psychological', 'Interpersonal Relations', 'Male', 'Mood Disorders', 'Object Attachment'] | 16,403,702 | [['M01.060.116'], ['F03.675.100'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['F03.615.250'], ['F03.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['F01.829.401... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identifying Immune Correlates of Protection Against Plasmodium falciparum Through a Novel Approach to Account for Heterogeneity in Malaria Exposure. | Background: A main criterion to identify malaria vaccine candidates is the proof that acquired immunity against them is associated with protection from disease. The age of the studied individuals, heterogeneous malaria exposure, and assumption of the maintenance of a baseline immune response can confound these associat... | ['Adaptive Immunity', 'Age Factors', 'Antibodies, Protozoan', 'Antigens, Protozoan', 'Child, Preschool', 'Female', 'Humans', 'Immunoglobulin G', 'Immunoglobulin M', 'Infant', 'Infant, Newborn', 'Malaria Vaccines', 'Malaria, Falciparum', 'Male', 'Mozambique', 'Plasmodium falciparum', 'Randomized Controlled Trials as Top... | 29,401,272 | [['G12.450.050'], ['N05.715.350.075', 'N06.850.490.250'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['D23.050.293'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A case of necrotizing scleritis resulting from Pseudomonas aeruginosa. | PURPOSE: The purpose of this study was to report a case of necrotizing scleritis resulting from Pseudomonas aeruginosa with no corneal infiltrate.RESULTS: A 75-year-old man presented with pain and redness in his left eye accompanied by fever of 3 days' duration. He was receiving chemotherapy for hepatic metastasis of a... | ['Administration, Oral', 'Aged', 'Anti-Bacterial Agents', 'Eye Infections, Bacterial', 'Humans', 'Imipenem', 'Male', 'Pseudomonas Infections', 'Pseudomonas aeruginosa', 'Scleritis'] | 19,724,201 | [['E02.319.267.100'], ['M01.060.116.100'], ['D27.505.954.122.085'], ['C01.150.252.289', 'C01.375.354', 'C11.294.354'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.589.099.124.300.500', 'D03.633.100.300.124.300.500'], ['C01.150.252.400.739'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['C... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells. | CD317/tetherin is a lipid raft-associated integral membrane protein with a novel topology. It has a short N-terminal cytosolic domain, a conventional transmembrane domain, and a C-terminal glycosyl-phosphatidylinositol anchor. We now show that CD317 is expressed at the apical surface of polarized epithelial cells, wher... | ['Actin Cytoskeleton', 'Actins', 'Animals', 'Antigens, CD', 'COS Cells', 'Caco-2 Cells', 'Cell Polarity', 'Chlorocebus aethiops', 'Cytoskeletal Proteins', 'Cytoskeleton', 'Down-Regulation', 'Epithelial Cells', 'GPI-Linked Proteins', 'GTPase-Activating Proteins', 'Humans', 'Membrane Glycoproteins', 'RNA, Small Interferi... | 19,273,615 | [['A11.284.430.214.190.750.050'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['A11.251.210.172.500', 'A11.329.228.220'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['G04.250'], ['B01.050.150.900.649.313.988.400.112.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
NAP and D-SAL: neuroprotection against the beta amyloid peptide (1-42). | INTRODUCTION: NAP (Asn-Ala-Pro-Val-Ser-Ile-Pro-Gln, single amino acid letter code, NAPVSIPQ), an eight amino acid neuroprotective peptide derived from activity-dependent neuroprotective protein (ADNP), exhibits some structural similarity to activity-dependent neurotropic factor-9 (ADNF-9; Ser-Alal-Leu-Leu-Arg-Ser-Ile-P... | ['Amino Acid Sequence', 'Amyloid beta-Peptides', 'Animals', 'Animals, Newborn', 'Cell Count', 'Cell Survival', 'Cells, Cultured', 'Cerebral Cortex', 'Neurons', 'Neuroprotective Agents', 'Oligopeptides', 'Peptide Fragments', 'Rats', 'Tubulin'] | 19,091,000 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['B01.050.050.282'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.346'], ['A11.251'], ['A08.186.211.200.885.287.500'], ['A08.675', 'A11.671'], ['D27.505.696.706.548... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Interspecific hybridization in Brassica juncea and Brassica tournefortii through embryo rescue and their evaluation for biotic and abiotic stress tolerance. | Interspecific hybrids were obtained in an otherwise incompatible cross Brassica juncea x Brassica tournefortii through in vitro culture of hybrid embryos. The best response was observed from culture of embryos excised 20 days after pollination on MS medium supplemented with kinetin, alpha-naphthylacetic acid, gibberell... | ['Brassica', 'Chimera', 'Crosses, Genetic', 'Hybridization, Genetic', 'Seeds', 'Sodium Chloride', 'Stress, Physiological'] | 11,831,375 | [['B01.650.940.800.575.912.250.157.200'], ['B05.200'], ['E05.393.281'], ['E05.820.150.390', 'G05.090.390'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['D01.210.450.150.875', 'D01.857.650'], ['G07.775']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Renal pro-inflammatory cytokine gene expression in diabetic nephropathy: effect of angiotensin-converting enzyme inhibition and pentoxifylline administration. | BACKGROUND: Recent studies have shown a role for inflammation in the pathogenesis of diabetic nephropathy (DN). Tumor necrosis factor (TNF)-alpha, interleukin (IL)-1 and IL-6 are cytokines with a prevalent pro-inflammatory activity. Our objective was to study the renal gene expression of TNF-alpha, IL-1 and IL-6 in DN ... | ['Albuminuria', 'Angiotensin-Converting Enzyme Inhibitors', 'Animals', 'Cytokines', 'Diabetic Nephropathies', 'Gene Expression', 'Hematologic Agents', 'Interleukin-1', 'Interleukin-6', 'Kidney', 'Male', 'Pentoxifylline', 'Rats', 'Rats, Sprague-Dawley', 'Streptozocin', 'Tumor Necrosis Factor-alpha'] | 17,167,242 | [['C12.777.934.734.269', 'C13.351.968.934.734.269', 'C23.888.942.750.269'], ['D27.505.519.389.745.085'], ['B01.050'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C12.777.419.192', 'C13.351.968.419.192', 'C19.246.099.875'], ['G05.297'], ['D27.505.954.502'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.4... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cannabis (medical marijuana) treatment for motor and non-motor symptoms of Parkinson disease: an open-label observational study. | OBJECTIVE: The use of cannabis as a therapeutic agent for various medical conditions has been well documented. However, clinical trials in patients with Parkinson disease (PD) have yielded conflicting results. The aim of the present open-label observational study was to assess the clinical effect of cannabis on motor a... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Hypokinesia', 'Male', 'Medical Marijuana', 'Middle Aged', 'Muscle Rigidity', 'Pain Measurement', 'Parkinson Disease', 'Severity of Illness Index', 'Sleep', 'Treatment Outcome', 'Tremor'] | 24,614,667 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.350.400', 'C23.888.592.350.400'], ['D26.528'], ['M01.060.116.630'], ['C05.651.504', 'C10.597.613.550.500', 'C23.888.592.608.550.500'], ['E01.370.600.550.324'], ['C10.228.140.079.862.500', 'C10.228.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Functional adaptability of muscle fibers to long-term resistance exercise. | PURPOSE: We compared the functional properties of muscle fibers from two groups of subjects that differed widely in their training history to investigate whether long-term resistance exercise alters the intrinsic contractile properties of skeletal muscle fibers.METHODS: Vastus lateralis muscle biopsies were obtained fr... | ['Adaptation, Physiological', 'Adult', 'Exercise', 'Humans', 'Hypertrophy', 'Male', 'Muscle Contraction', 'Muscle Fibers, Fast-Twitch', 'Muscle Fibers, Slow-Twitch', 'Myosin Heavy Chains', 'Physical Fitness', 'Weight Lifting'] | 12,783,042 | [['G07.025', 'G16.012.500'], ['M01.060.116'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.775'], ['G11.427.494'], ['A10.690.552.500.500.600', 'A11.620.249.400'], ['A10.690.552.500.500.700', 'A11.620.249.700'], ['D05.750.078.730.475.100', 'D08.811.277.040.025.193.750.24... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Axitinib with or without dose titration for first-line metastatic renal-cell carcinoma: a randomised double-blind phase 2 trial. | BACKGROUND: Population pharmacokinetic data suggest axitinib plasma exposure correlates with efficacy in metastatic renal-cell carcinoma. Axitinib dose titration might optimise exposure and improve outcomes. We prospectively assessed the efficacy and safety of axitinib dose titration in previously untreated patients wi... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Agents', 'Axitinib', 'Carcinoma, Renal Cell', 'Disease Progression', 'Disease-Free Survival', 'Double-Blind Method', 'Europe', 'Female', 'Humans', 'Imidazoles', 'Indazoles', 'Japan', 'Kaplan-Meier Estimate', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Prospective S... | 24,140,184 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248'], ['D02.065.277.051', 'D02.241.223.100.100.115', 'D02.455.426.559.389.127.085.093', 'D03.383.129.539.487.065', 'D03.633.100.449.065'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hepatic lactate uptake versus leg lactate output during exercise in humans. | The exponential rise in blood lactate with exercise intensity may be influenced by hepatic lactate uptake. We compared muscle-derived lactate to the hepatic elimination during 2 h prolonged cycling (62 +/- 4% of maximal O(2) uptake, (.)Vo(2max)) followed by incremental exercise in seven healthy men. Hepatic blood flow ... | ['Adult', 'Blood Gas Analysis', 'Exercise', 'Exercise Test', 'Glucose', 'Hemodynamics', 'Humans', 'Lactic Acid', 'Leg', 'Liver', 'Male', 'Muscle, Skeletal', 'Oxygen Consumption', 'Regional Blood Flow'] | 17,656,631 | [['M01.060.116'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['G11.427.410.698.277', 'I03.350'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['D09.947.875.359.448'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459.450'], ['A01.378.61... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Perceptions of influenza and pneumococcal vaccine uptake by older persons in Australia. | BACKGROUND: Influenza and pneumococcal vaccinations reduce adverse health outcomes in older adults. The Australian National Immunisation Program (NIP) provides free seasonal influenza and pneumococcal vaccinations for adults ?65 y. Guidelines recommend all adults ?65 y receive one dose of 23-valent pneumococcal polysac... | ['Aged', 'Aged, 80 and over', 'Australia', 'Female', 'Humans', 'Immunization Programs', 'Influenza Vaccines', 'Influenza, Human', 'Male', 'Pneumococcal Infections', 'Pneumococcal Vaccines', 'Vaccination'] | 31,277,956 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.639.100', 'Z01.678.100.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.726.608'], ['D20.215.894.899.302'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['C01.150.252.410.890.670'], ['D20.215.894.135.750.600'], ['E02.095.465.425.400.530.890... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Pre-treatment with bone marrow-derived mesenchymal stem cells inhibits systemic intravascular coagulation and attenuates organ dysfunction in lipopolysaccharide-induced disseminated intravascular coagulation rat model. | BACKGROUND: Bacterial lipopolysaccharide (LPS) can activate immunological cells to secrete various proinflammatory cytokines involved in the pathophysiological process of disseminated intravascular coagulation (DIC) during infection. In recent years, it has been found that bone marrow-derived mesenchymal stem cells (BM... | ['Alanine Transaminase', 'Animals', 'Blood Coagulation', 'Bone Marrow Cells', 'Creatinine', 'Interferon-gamma', 'Interleukin-1beta', 'Lipopolysaccharides', 'Male', 'Mesenchymal Stem Cells', 'Rats', 'Rats, Wistar', 'Tumor Necrosis Factor-alpha'] | 22,800,895 | [['D08.811.913.477.700.100'], ['B01.050'], ['G09.188.390.150'], ['A11.148', 'A15.378.316'], ['D03.383.129.308.207'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615.350'], ['D12.644.276.374.465.010.600', 'D1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lack of correlation between occlusion and reperfusion arrhythmias in the cat. | Recently it has been stated that in dogs absence of arrhythmias during coronary artery occlusion identifies a subgroup at almost no risk for developing ventricular fibrillation (VF) during reperfusion. A potential implication would be that prevention of ischemic arrhythmias may also prevent the most severe reperfusion ... | ['Animals', 'Arrhythmias, Cardiac', 'Arterial Occlusive Diseases', 'Cats', 'Coronary Disease', 'Heart Ventricles', 'Myocardial Contraction', 'Perfusion', 'Time Factors', 'Ventricular Fibrillation'] | 3,993,527 | [['B01.050'], ['C14.280.067', 'C23.550.073'], ['C14.907.137'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C14.280.647.250', 'C14.907.585.250'], ['A07.541.560'], ['G09.330.580', 'G11.427.494.570'], ['E05.680'], ['G01.910.857'], ['C14.280.067.922', 'C23.550.073.922']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An analogue of met-enkephalin attenuates the pituitary-adrenal response to ovine corticotrophin releasing factor. | The met-enkephalin analogue, DAMME, suppresses the pituitary-adrenal axis in normal subjects; it is not clear whether this occurs at the level of the pituitary or above. We therefore administered synthetic ovine corticotrophin releasing factor (CRF-41) 100 micrograms i.v. to a group of normal male subjects, with or wit... | ['Adolescent', 'Adrenocorticotropic Hormone', 'Adult', 'Corticotropin-Releasing Hormone', 'D-Ala(2),MePhe(4),Met(0)-ol-enkephalin', 'Humans', 'Hydrocortisone', 'Male', 'Peptide Fragments', 'Pituitary-Adrenal System'] | 3,040,301 | [['M01.060.057'], ['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['M01.060.116'], ['D06.472.699.327.740.140', 'D12.644.400.400.740.140', 'D12.644.548.365.740.140', 'D1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dilatation of the aneurysmal sac after total arch replacement. | In our institution, total arch replacement for distal arch aneurysms is performed through a median sternotomy with antegrade selective cerebral perfusion. The distal anastomosis to the completely transected descending aorta is made through the aneurysmal sac. We report on three interesting cases presenting late dilatat... | ['Aged', 'Aged, 80 and over', 'Anastomosis, Surgical', 'Aneurysm, False', 'Aorta, Thoracic', 'Aortic Aneurysm, Thoracic', 'Embolization, Therapeutic', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Radiography', 'Risk Assessment', 'Treatment Outcome', 'Vascular Surgical Procedures'] | 18,222,284 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.035'], ['C14.907.055.090'], ['A07.015.114.056.372'], ['C14.907.055.239.125', 'C14.907.109.139.125'], ['E02.520.360', 'E02.926.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Altered bidirectional plasticity and reduced implicit motor learning in concussed athletes. | Persistent motor/cognitive alterations and increased prevalence of Alzheimer's disease are known consequences of recurrent sports concussions, the most prevalent cause of mild traumatic brain injury (TBI) among youth. Animal models of TBI demonstrated that impaired learning was related to persistent synaptic plasticity... | ['Adult', 'Analysis of Variance', 'Athletic Injuries', 'Brain Concussion', 'Brain-Derived Neurotrophic Factor', 'Electric Stimulation', 'Electromyography', 'Evoked Potentials, Motor', 'Football', 'Humans', 'Learning Disabilities', 'Male', 'Methionine', 'Motor Activity', 'Motor Cortex', 'Neural Inhibition', 'Neuronal Pl... | 21,572,090 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C26.115'], ['C10.228.140.199.444.250', 'C10.900.300.087.235.250', 'C10.900.300.350.300', 'C26.915.300.200.194.250', 'C26.915.300.450.500', 'C26.974.382.200'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Disc... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
[Measles in 2010. Knowledge and vaccination status of medical students]. | OBJECTIVES: In 2002, the WHO Regional Office for Europe developed a strategic plan for measles in the WHO European Region. WHO recommends that at least 95% of children receive two doses of measles vaccine. This plan targeted the elimination of measles for the year 2010 and is supported by the Federal Republic of German... | ['Adult', 'Female', 'Germany', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Measles', 'Measles Vaccine', 'Students, Medical', 'Vaccination', 'Young Adult'] | 21,290,279 | [['M01.060.116'], ['Z01.542.315'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.925.782.580.600.500.500'], ['D20.215.894.899.404'], ['M01.848.769.602'], ['E02.095.465.425.400.530.890', 'E05.478.550.600.890', 'N02.421.726.758.310.890', 'N06.850.780.200.425.900', 'N06.850... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
CCP4i2: the new graphical user interface to the CCP4 program suite. | The CCP4 (Collaborative Computational Project, Number 4) software suite for macromolecular structure determination by X-ray crystallography groups brings together many programs and libraries that, by means of well established conventions, interoperate effectively without adhering to strict design guidelines. Because of... | ['Computer Graphics', 'Crystallography, X-Ray', 'Macromolecular Substances', 'Molecular Structure', 'Proteins', 'Software', 'User-Computer Interface'] | 29,533,233 | [['L01.224.108', 'L01.296.110'], ['E05.196.309.742.225'], ['D05'], ['G02.111.570', 'G02.466'], ['D12.776'], ['L01.224.900'], ['L01.224.900.910']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of larval density and substrate quality on the wing geometry of Stomoxys calcitrans L. (Diptera: Muscidae). | BACKGROUND: In insects, oviposition decisions may lead to egg deposition in substrates with different larval density and nutritional levels. Individuals developing in such substrates may present plasticity in their phenotype. Here, we investigated the effect of two factors related to oviposition decisions, namely larva... | ['Animals', 'Camelus', 'Cattle', 'Equidae', 'Feces', 'Female', 'Larva', 'Muscidae', 'Oviposition', 'Population Density', 'Sheep', 'Wings, Animal'] | 31,077,236 | [['B01.050'], ['B01.050.150.900.649.313.500.190.180'], ['B01.050.150.900.649.313.500.380.271'], ['B01.050.150.900.649.313.984.235'], ['A12.459'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B01.050.500.131.617.720.500.500.750.642'], ['G08.686.784.480'], ['N01.224.600', 'N06.850.505.400.600'], ['B01.050.150.900.649.31... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Anticancer effect of 2,7-dihydroxy-3-methylanthraquinone on human gastric cancer SGC-7901 cells in vitro and in vivo. | CONTEXT: 2,7-Dihydroxy-3-methylanthraquinone (DDMN) is reported to have a remarkable anticancer activity against gastric cancer SGC-7901 cells.OBJECTIVE: The objective of this study is to study the anticancer effect and mechanism of DDMN on SGC-7901 cells.MATERIALS AND METHODS: The MTT assay was used to determine the e... | ['Animals', 'Anthraquinones', 'Antineoplastic Agents, Phytogenic', 'Apoptosis', 'Cell Culture Techniques', 'Cell Line, Tumor', 'Cell Survival', 'Dose-Response Relationship, Drug', 'Drugs, Chinese Herbal', 'Flow Cytometry', 'Gene Expression Regulation, Neoplastic', 'Hedyotis', 'Humans', 'Mice, Nude', 'Mitochondria', 'St... | 25,853,970 | [['B01.050'], ['D02.455.426.559.847.117.159', 'D02.806.100', 'D04.615.117.159'], ['D27.505.954.248.179'], ['G04.146.954.035'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['G07.690.773.875', 'G07.690.936.500'], ['D20.215.784.500.350'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Apomorphine-haloperidol interactions: different types of antagonism in cortical and subcortical brain regions. | Apomorphine, a dopamine (DA) receptor stimulant induced a dose-dependent decrease in the content of the dopamine metabolites 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) in the olfactory tubercle and striatum of rats, but it was ineffective in the frontal cortex. Apomorphine also antagonized the h... | ['3,4-Dihydroxyphenylacetic Acid', 'Animals', 'Apomorphine', 'Caudate Nucleus', 'Corpus Striatum', 'Dopamine', 'Dose-Response Relationship, Drug', 'Frontal Lobe', 'Haloperidol', 'Homovanillic Acid', 'Male', 'Olfactory Bulb', 'Rats', 'Receptors, Dopamine'] | 7,470,869 | [['D02.241.223.601.220'], ['B01.050'], ['D03.132.098.038.290', 'D03.633.100.531.085.030.290', 'D03.633.400.095.290'], ['A08.186.211.200.885.287.249.487.550.184'], ['A08.186.211.200.885.287.249.487'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['G07.690.773.875', 'G07.690.936.500'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phosphatidylinositol 3'-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase. | Serine phosphorylation of insulin receptor substrate-1 (IRS-1) has been proposed as a counter-regulatory mechanism in insulin and cytokine signalling. Here we report that IRS-1 is phosphorylated by a wortmannin insensitive phosphatidylinositol 3'-kinase (PI 3-kinase)-associated serine kinase (PAS kinase) distinct from ... | ['Androstadienes', 'Humans', 'Insulin', 'Insulin Receptor Substrate Proteins', 'Intracellular Signaling Peptides and Proteins', 'Phosphatidylinositol 3-Kinases', 'Phosphoproteins', 'Phosphorylation', 'Protein Phosphatase 2', 'Protein Tyrosine Phosphatase, Non-Receptor Type 11', 'Protein Tyrosine Phosphatase, Non-Recept... | 9,761,740 | [['D04.210.500.054.079.129'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D12.644.360.024.301', 'D12.776.157.057.045', 'D12.776.476.024.382'], ['D12.644.360', 'D12.776.476'], ['D08.811.913.696.620.500'], ['D12.776.744'], ['G02.111.665', 'G02.607.780... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Natural history and prognostic factors of primary biliary cirrhosis in Taiwan: a follow-up study up to 18 years. | PURPOSE: The natural history of primary biliary cirrhosis (PBC) has been little studied in Asia. We conducted a Taiwanese cohort study on the natural history of PBC and analysed the prognostic factors.METHODS: This study enrolled 96 consecutive PBC patients between 1985 and 2006 to evaluate the baseline characteristics... | ['Adult', 'Aged', 'Aged, 80 and over', 'Bilirubin', 'Carcinoma, Hepatocellular', 'Cohort Studies', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Liver Cirrhosis, Biliary', 'Liver Neoplasms', 'Logistic Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Prognosis', 'Retrospective Studies', 'Serum Albumin', 'Taiwan... | 18,346,129 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Protein kinase C activation by phorbol esters induces chromaffin cell cortical filamentous actin disassembly and increases the initial rate of exocytosis in response to nicotinic receptor stimulation. | Nicotinic stimulation and high K+ depolarization of bovine chromaffin cells cause disassembly of cortical filamentous actin networks. Previous work from our laboratory has demonstrated that disassembly of actin filaments is Ca(2+)-dependent, precedes exocytosis and occurs in cortical areas of low cytoplasmic viscosity ... | ['Actins', 'Adrenal Medulla', 'Alkaloids', 'Animals', 'Calcium', 'Cattle', 'Enzyme Activation', 'Exocytosis', 'Kinetics', 'Macromolecular Substances', 'Microscopy, Fluorescence', 'Naphthalenes', 'Nicotine', 'Norepinephrine', 'Polycyclic Compounds', 'Protein Kinase C', 'Receptors, Nicotinic', 'Sphingosine', 'Staurospori... | 1,281,530 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['A06.300.071.265'], ['D03.132'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.500.380.271'], ['G02.111.263', 'G03.328'], ['G04.468'], ['G01.374.661', 'G02.111.490'], ['D05'], ['E01.370.350.515.458',... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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