Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Ubr1p-Cup9p-Ptr2p pathway involves in the sensitivity to readthrough compounds negamycin derivatives in budding yeast. | In this study, we found that dipeptide transporter Ptr2p is the putative transporter of read-through compounds (+)-negamycin derivatives TCP-126 and TCP-112, in budding yeast. Ptr2p expression and activity were correlated with the TCP-112 sensitivity, and dipeptide with high affinity to Ptr2p suppressed the TCP-112 act... | ['Amino Acids, Diamino', 'Biological Transport', 'Genes, Fungal', 'Homeodomain Proteins', 'Membrane Transport Proteins', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Transcription Factors', 'Ubiquitin-Protein Ligases'] | 31,159,660 | [['D12.125.095'], ['G03.143'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['D12.776.260.400'], ['D12.776.157.530', 'D12.776.543.585'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.354.750'], ['D12.776.930'], ['D08.811.464.938.750']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Investigation on etiology of hepatic venous obstruction Budd-Chiari syndrome. | Budd-Chiari syndrome (BCS) is an uncommon clinical condition with a complex etiology. Pathogenesis of BCS is still poorly understood. We included hepatic veno-occlusive lesion tissues of 20 patients (patients group) with hepatic venous obstruction BCS and compared with 20 similar tissues with other etiologies (control ... | ['Adult', 'Budd-Chiari Syndrome', 'Connective Tissue', 'Female', 'Humans', 'Immunohistochemistry', 'Liver', 'Male', 'Middle Aged', 'Myocytes, Smooth Muscle', 'Proliferating Cell Nuclear Antigen', 'Proto-Oncogene Proteins c-myc', 'Tumor Suppressor Protein p53'] | 25,096,503 | [['M01.060.116'], ['C06.552.347', 'C14.907.355.830.925.275'], ['A10.165'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.18... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Permeabilizing and hemolytic action of large and small polyene antibiotics on human erythrocytes. | The effects of large polyenes (heptaenes and the "degenerate heptaene" nystatin) on human erythrocytes were found to occur in three separate stages. Stage I was a reversible increase in cell membrane permeability to monovalent cations and occurred at low antibiotic concentrations. At intermediate antibiotic concentrati... | ['Anti-Bacterial Agents', 'Binding Sites', 'Carbohydrates', 'Cell Membrane Permeability', 'Erythrocyte Membrane', 'Erythrocytes', 'Hemolysis', 'Humans', 'In Vitro Techniques', 'Molecular Weight', 'Polyenes', 'Potassium', 'Sodium'] | 7,447,419 | [['D27.505.954.122.085'], ['G02.111.570.120'], ['D09'], ['G03.143.335', 'G04.175'], ['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['C23.550.403', 'G12.122.545'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['G02.494'], ['D02.455.326.2... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Inhibitory effect on Microcystis aeruginosa as well as separation and identification of the allelochemicals of Allium cepa]. | OBJECTIVE: To uncover the inhibition of Allium cepa (onion) on Microcystis aeruginosa, and identify the allelochemicals in onion.METHODS: The inhibition of different concentrations of onion bulb and onion leaf water extracts on M. aeruginosa were investigated, and the allelochemicals of onion bulb were extracted and id... | ['Gas Chromatography-Mass Spectrometry', 'Microcystis', 'Onions', 'Pheromones', 'Plant Extracts', 'Plant Leaves', 'Water'] | 26,591,781 | [['E05.196.181.349.500', 'E05.196.566.500'], ['B03.280.500', 'B03.440.475.100.500'], ['B01.650.940.800.575.912.250.618.100.050.060.600'], ['D23.641'], ['D20.215.784.500', 'D26.667'], ['A18.024.812'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
What do neurologists think about their role in neuroimaging training and practice? | In 1996, a survey of the members of the American Academy of Neurology revealed the following facts and opinions: (1) On an average month, each respondent ordered 15 computed tomography, 22 magnetic resonance imaging, 13 ultrasound and 1 single-photon emission computerized tomography studies. (2) Most respondents did no... | ['Diagnostic Imaging', 'Humans', 'Neurology', 'Patient Care Management', "Physician's Role", 'Surveys and Questionnaires', 'United States'] | 16,173,163 | [['E01.370.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.600'], ['N04.590'], ['F01.829.316.616.625.600'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['Z01.107.567.875']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Aortic valve annulus diameter in Chinese patients with severe calcific aortic valve stenosis: implications for transcatheter aortic valve implantation. | OBJECTIVES: The objective of the study was to describe the distribution and determine the predictors of aortic valve annulus diameter (AVAD) in Chinese patients with severe calcific aortic valve stenosis (CAS).BACKGROUND: AVAD in Chinese patients with CAS has not been reported. Predictors of AVAD in patients with CAS a... | ['Aged', 'Aged, 80 and over', 'Anthropometry', 'Aortic Valve Stenosis', 'Asian Continental Ancestry Group', 'Calcinosis', 'Cardiac Catheterization', 'China', 'Chordae Tendineae', 'Cohort Studies', 'Echocardiography, Doppler', 'Echocardiography, Transesophageal', 'Female', 'Follow-Up Studies', 'Heart Valve Prosthesis', ... | 21,953,731 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['C14.280.484.048.750', 'C14.280.955.249'], ['M01.686.508.200'], ['C18.452.174.130'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['Z01.252.474.164'], ['A07.541.510.240'], ['E05.318.372.500.750', 'N05.715.36... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Treatment of Physiologic Gingival Pigmentation with Surgical Blade: A 25-Year Follow-up. | Gingival hyperpigmentation in the anterior region in people with a high smile line is an esthetic concern. Gingival depigmentation can be achieved through various procedures. Most techniques have shown successful short-term results; however, recurrence is observed in 50% of patients after 2 to 4 years. A 46-year-old wo... | ['Female', 'Follow-Up Studies', 'Gingiva', 'Gingival Diseases', 'Gingivectomy', 'Humans', 'Hyperpigmentation', 'Middle Aged', 'Time Factors'] | 30,118,532 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A14.549.167.646.480'], ['C07.465.714.258'], ['E04.545.350', 'E06.645.350', 'E06.721.321'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.621.430'], ['M01.060.116.630'], ['G01.910.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Trichomonas vaginalis lipophosphoglycan mutants have reduced adherence and cytotoxicity to human ectocervical cells. | The extracellular human pathogen Trichomonas vaginalis is covered by a dense glycocalyx thought to play a role in host-parasite interactions. The main component of the glycocalyx is lipophosphoglycan (LPG), a polysaccharide anchored in the plasma membrane by inositol phosphoceramide. To study the role of LPG in trichom... | ['Animals', 'Cell Adhesion', 'Cells, Cultured', 'Cervix Uteri', 'Epithelial Cells', 'Ethyl Methanesulfonate', 'Female', 'Galactose', 'Glucosamine', 'Glycosphingolipids', 'Host-Parasite Interactions', 'Humans', 'Mutagens', 'Plant Lectins', 'Trichomonas vaginalis', 'Wheat Germ Agglutinins'] | 16,278,462 | [['B01.050'], ['G04.022'], ['A11.251'], ['A05.360.319.679.256'], ['A11.436'], ['D02.455.326.146.100.050.500.300', 'D02.886.645.600.055.050.510.300'], ['D09.947.875.359.377'], ['D09.067.342.531'], ['D09.400.410.420', 'D10.390.470', 'D10.570.877.360'], ['G16.527.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A second nonrandom translocation, der(16)t(1;16)(q21;q13), in Ewing sarcoma and peripheral neuroectodermal tumor. | The majority of Ewing sarcomas and peripheral neuroectodermal tumors (PNET) that have been karyotyped contain a specific translocation, t(11;22)(q23;q11). We report here a second nonrandom translocation, der(16)t(1;16)(q21;q13), in 2 of 20 cases of Ewing sarcoma (seven previously unreported) and 2 of 7 cases of PNET (a... | ['Adolescent', 'Adult', 'Child', 'Chromosome Banding', 'Chromosomes, Human, Pair 1', 'Chromosomes, Human, Pair 16', 'Female', 'Humans', 'Karyotyping', 'Male', 'Middle Aged', 'Neoplasms, Germ Cell and Embryonal', 'Peripheral Nervous System Neoplasms', 'Sarcoma, Ewing', 'Translocation, Genetic'] | 2,164,462 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E01.370.225.500.385.130', 'E01.370.225.500.620.670.130', 'E01.370.225.750.600.670.130', 'E05.200.500.385.130', 'E05.200.500.620.670.130', 'E05.200.750.600.670.130', 'E05.242.385.130', 'E05.393.285.130'], ['A11.284.187.520.300.235.240', 'G05.360.162.520.300.235.240']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The polarized distribution of Na+,K+-ATPase: role of the interaction between {beta} subunits. | The very existence of higher metazoans depends on the vectorial transport of substances across epithelia. A crucial element of this transport is the membrane enzyme Na(+),K(+)-ATPase. Not only is this enzyme distributed in a polarized manner in a restricted domain of the plasma membrane but also it creates the ionic gr... | ['Animals', 'Cell Line', 'Cell Polarity', 'Cricetinae', 'Cricetulus', 'Dogs', 'Epithelial Cells', 'Fluorescence Resonance Energy Transfer', 'Models, Molecular', 'Protein Binding', 'Protein Conformation', 'Protein Isoforms', 'Protein Subunits', 'Rats', 'Recombinant Fusion Proteins', 'Sodium-Potassium-Exchanging ATPase'] | 20,444,976 | [['B01.050'], ['A11.251.210'], ['G04.250'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['B01.050.150.900.649.313.750.250.216.200'], ['A11.436'], ['E05.196.712.516.600.676.500', 'G01.154.240.280', 'G02.111.255.280'], ['E05.599.595'], ['G02.111.679', 'G03.808'], ['G02.11... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Apoptosis-associated markers and clinical outcome in human oral squamous cell carcinomas. | BACKGROUND: Apoptosis is a genetically regulated cell death involved in the deletion of cells in normal or malignant tissues. Proteins of the Bcl-2 family play a key role in the control of apoptosis and carry out both pro-apoptotic and anti-apoptotic functions. The present study evaluated the prognostic value of Bcl-2 ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Apoptosis', 'Biomarkers, Tumor', 'Carcinoma, Squamous Cell', 'Female', 'Gene Expression', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Mouth Neoplasms', 'Neoplasm Staging', 'Prognosis', 'Proportional Hazards Models', 'Proto-... | 18,410,312 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G04.146.954.035'], ['D23.101.140'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['G05.297'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['M01.060.11... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hypolipidemic activity of Anethum graveolens in rats. | The aerial parts of Anethum graveolens (dillweed) are used in Iran as a hypolipidemic agent. The scientific basis for its use has yet to be established. In this study the hypolipidemic activity of dill powder and its essential oil (its most important fraction) were evaluated in male Wistar rats (180 +/- 20 g) fed a hig... | ['Anethum graveolens', 'Animals', 'Cholesterol', 'Cholesterol, Dietary', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Dose-Response Relationship, Drug', 'Hypolipidemic Agents', 'Male', 'Oils, Volatile', 'Phytotherapy', 'Plant Components, Aerial', 'Plant Extracts', 'Rats', 'Rats, Wistar', 'Triglycerides'] | 18,058,989 | [['B01.650.940.800.575.912.250.075.077'], ['B01.050'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.225', 'D10.212.302.347', 'D10.570.938.208.222'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['D04.210.500.247... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Concentration kinetics of secoisolariciresinol diglucoside and its biosynthetic precursor coniferin in developing flaxseed. | INTRODUCTION: In the plant kingdom, flaxseed (Linum usitatissimum L.) is the richest source of secoisolariciresinol diglucoside (SDG), which is of great interest because of its potential health benefits for human beings. The information about the kinetics of SDG formation during flaxseed development is rare and incompl... | ['Butylene Glycols', 'Chromatography, High Pressure Liquid', 'Cinnamates', 'Flax', 'Glucosides', 'Kinetics', 'Reproducibility of Results', 'Seeds'] | 22,689,568 | [['D02.033.455.125'], ['E05.196.181.400.300'], ['D02.241.223.200'], ['B01.650.940.800.575.912.250.859.797.620.500'], ['D09.408.348'], ['G01.374.661', 'G02.111.490'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Predictive value of intravenous glucose tolerance test insulin secretion less than or greater than the first percentile in islet cell antibody positive relatives of type 1 (insulin-dependent) diabetic patients. | We have followed-up 35 islet cell antibody-positive first degree relatives of patients with Type 1 (insulin-dependent) diabetes mellitus for an average of 1,300 days with sequential intravenous glucose tolerance tests. At the time of analysis and manuscript submission approximately half (18 of 35) had developed diabete... | ['Administration, Oral', 'Adolescent', 'Adult', 'Aged', 'Autoantibodies', 'Biomarkers', 'Child', 'Child, Preschool', 'Diabetes Mellitus, Type 1', 'Follow-Up Studies', 'Glucose', 'Glucose Tolerance Test', 'HLA-DR Antigens', 'Humans', 'Infusions, Intravenous', 'Insulin', 'Insulin Secretion', 'Middle Aged', 'Prediabetic S... | 2,065,854 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D23.101'], ['M01.060.406'], ['M01.060.406.448'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['E05.318.372.500.750.249', 'N05.715.360.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Exploring physiotherapists' experiences of implementing a cognitive behavioural approach for managing low back pain and identifying barriers to long-term implementation. | OBJECTIVES: Our objectives were two-fold: (i) to describe physiotherapists' experiences of implementing a cognitive behavioural approach (CBA) for managing low back pain (LBP) after completing an extensive online training course (iBeST), and (ii) to identify how iBeST could be enhanced to support long-term implementati... | ['Adult', 'Aged', 'Attitude of Health Personnel', 'Education, Continuing', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Interviews as Topic', 'Low Back Pain', 'Male', 'Middle Aged', 'Physical Therapists', 'Physical Therapy Modalities', 'Professional Role', 'United Kingdom'] | 28,826,744 | [['M01.060.116'], ['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['I02.358.212'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['C23.888.592.612.107.400'], ['M01.060.116.630'], ['M01.5... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
[Evaluation of a new method for detection of obstructive disease in children asthma: the negative expiratory pressure (NEP)]. | INTRODUCTION: To take in charge of an asthmatic child it is necessary to evaluate the lung function.METHODS: In this study, the Negative Expiratory Pressure (NEP) has been used for the first time in children with asthma. After lung spirometry by plethysmography, we have used the NEP to assess the prevalence of expirato... | ['Adolescent', 'Asthma', 'Child', 'Exhalation', 'Forced Expiratory Volume', 'Functional Residual Capacity', 'Humans', 'Inspiratory Capacity', 'Lung Diseases, Obstructive', 'Maximal Expiratory Flow-Volume Curves', 'Plethysmography', 'Posture', 'Prospective Studies', 'Pulmonary Ventilation', 'Residual Volume', 'Spirometr... | 16,023,842 | [['M01.060.057'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['G09.772.705.700.275'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['E01.370.386.700.485.750.275', 'G09.772.850.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.700.485.750.900.350', '... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Salmonella enterica serovar Typhimurium expressing mutant lipid A with decreased endotoxicity causes maturation of murine dendritic cells. | A major Salmonella component involved in cellular activation is the lipopolysaccharide (LPS) molecule which can act as a dendritic cell (DC) stimulator. The structure of the lipid A domain of the LPS molecule dictates its immunostimulatory capacity with various cell types. In this study, the role of lipid A as an integ... | ['Animals', 'Dendritic Cells', 'Interleukin-1', 'Lipid A', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mutation', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type II', 'Salmonella typhimurium', 'Tumor Necrosis Factor-alpha'] | 14,573,628 | [['B01.050'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.529.374.465.131', 'D23.529.374.500.400'], ['D09.698.718.450.500', 'D10.494.500', 'D23.050.161.616.525.500', 'D23.946.123.3... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of antibody in cytotoxicity by lymphocytes armed against 253J bladder cancer line. | The role of antibody-dependent cell-mediated cytotoxicity (ADCC) in cytotoxicity mediated by antibody-armed effector cells was examined. Cytotoxicity mediated by unsensitized human peripheral blood mononuclear cells (MNC) directed against the human bladder cancer cell line, 253J, was significantly enhanced when MNC wer... | ['Absorption', 'Animals', 'Antibodies', 'Antibody-Dependent Cell Cytotoxicity', 'Cell Adhesion', 'Cell Line', 'Cytotoxicity, Immunologic', 'Humans', 'Immune Sera', 'Lymphocytes', 'Rabbits', 'Urinary Bladder Neoplasms'] | 7,298,218 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G12.287.070'], ['G04.022'], ['A11.251.210'], ['G12.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.207.152.846.500', 'D12.776.124.486.485.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acute lung injury induced by lipopolysaccharide is inhibited by wogonin in mice via reduction of Akt phosphorylation and RhoA activation. | OBJECTIVES: Neutrophil infiltration into the lung is the critical characteristic of acute lung injury (ALI), which is a clinical state with acute inflammatory syndrome. Up to now, there is no effective medicine for ALI. Wogonin has been shown to posses serval biological activities including anti-inflammation, anti-oxid... | ['Acute Lung Injury', 'Animals', 'Drugs, Chinese Herbal', 'Flavanones', 'Intercellular Adhesion Molecule-1', 'Lipopolysaccharides', 'Male', 'Mice, Inbred ICR', 'Phosphorylation', 'Proto-Oncogene Proteins c-akt', 'Scutellaria', 'Vascular Cell Adhesion Molecule-1', 'rho GTP-Binding Proteins', 'rhoA GTP-Binding Protein'] | 26,749,510 | [['C08.381.520.500'], ['B01.050'], ['D20.215.784.500.350', 'D26.335'], ['D03.383.663.283.266.450.252', 'D03.633.100.150.266.450.252'], ['D12.776.395.550.200.450', 'D12.776.543.550.200.450', 'D23.050.301.350.450'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['B01.050.050... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
MDR-1 genotypes and quetiapine pharmacokinetics in healthy volunteers. | BACKGROUND: P-glycoprotein is an efflux transporter encoded by the multidrug-resistance MDR-1 gene, which influences the absorption and excretion of a variety of drugs. The relation between quetiapine pharmacokinetics and MDR-1 genetic polymorphisms remains controversial. Therefore, the aim of the present study was to ... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Antipsychotic Agents', 'Dibenzothiazepines', 'Female', 'Healthy Volunteers', 'Humans', 'Male', 'Polymorphism, Single Nucleotide', 'Quetiapine Fumarate'] | 23,740,681 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['D02.886.680.70... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Proximity of schools in Detroit, Michigan to automobile and truck traffic. | Exposure to traffic-related air pollutants, which has been associated with a range of adverse health effects, often is represented using indirect proxies or surrogate exposure measures, most commonly, the proximity to busy roads. This study examines the proximity of grade K-12 schools to high traffic roads in Wayne Cou... | ['Adolescent', 'Air Pollution', 'Automobiles', 'Child', 'Child, Preschool', 'Environmental Exposure', 'Environmental Monitoring', 'Female', 'Humans', 'Male', 'Michigan', 'Motor Vehicles', 'Schools', 'Transportation', 'Vehicle Emissions'] | 16,622,481 | [['M01.060.057'], ['N06.850.460.100'], ['J01.937.500.100'], ['M01.060.406'], ['M01.060.406.448'], ['N06.850.460.350'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.350.500', 'Z01.107.567.875.510.500'], ['J01.937.500'], ['I02.783', 'J03.832'], ['J01.937']... | ['Named Groups [M]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
The role of Pseudomonas aeruginosa elastase as a potent inflammatory factor in a rat air pouch inflammation model. | Pseudomonas aeruginosa, an opportunistic pathogen, can cause life threatening infections in patients compromised by underlying respiratory disease like bronchiectasis, cystic fibrosis and diffuse panbronchiolitis. Most strains of P. aeruginosa produce some kind of protease with broad substrate specificities during the ... | ['Air', 'Animals', 'Bacterial Proteins', 'Bacterial Toxins', 'Chemotaxis, Leukocyte', 'Disease Models, Animal', 'Inflammation Mediators', 'Injections, Subcutaneous', 'Interleukin-8', 'Lipopolysaccharides', 'Male', 'Metalloendopeptidases', 'Neutrophils', 'Pseudomonas aeruginosa', 'Rats', 'Rats, Sprague-Dawley'] | 10,459,586 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['B01.050'], ['D12.776.097'], ['D23.946.123'], ['G04.198.424.233'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D23.469'], ['E02.319.267.530.620'], ['D12.644.276.374.200.120.800', 'D12.644.276.374.465.312', 'D12.776.467.374.200.120.800', 'D12.776.467.374.465.246', '... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Food sources of vitamin D and their association with 25-hydroxyvitamin D status in Dutch older adults. | Various populations are at increased risk of developing a low vitamin D status, in particular older adults. Whereas sun exposure is considered the main source of vitamin D, especially during summer, dietary contributions should not be underestimated. This study aims to identify food sources of vitamin D that associate ... | ['Aged', 'Butter', 'Cross-Sectional Studies', 'Diet', 'Dietary Supplements', 'Female', 'Food', 'Humans', 'Male', 'Margarine', 'Middle Aged', 'Netherlands', 'Nutritional Status', 'Vitamin D', 'Vitamin D Deficiency', 'Vitamins'] | 27,777,183 | [['M01.060.116.100'], ['D10.212.302.199', 'G07.203.300.350.100', 'G07.203.300.375.200', 'J02.500.350.100', 'J02.500.375.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.650.240'], ['G07.203.300.456', 'J02.500.456'], ['G07.203.300', 'J02.500'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Breakaway forces of flat and domed surfaced Magfit implant magnet attachments. | The aim of this in vitro study was to compare the resistance to separation (breakaway force) of flat (Magfit-IP-BF) and domed (Magfit-IP-BD) implant magnet attachments subjected to non-axial forces. The separating forces were applied by an Instron Universal Testing Instrument to single magnet attachments at angles of 0... | ['Dental Implants', 'Dental Prosthesis Retention', 'Dental Prosthesis, Implant-Supported', 'Magnetics', 'Tensile Strength'] | 17,378,452 | [['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E06.780.346.687'], ['E06.780.346.706', 'E07.695.190.185'], ['H01.671.493'], ['G01.374.850']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[The change rules and correlation between specific leaf weight and dry weight of rhizoma of Atractylodes macrocephala]. | OBJECTIVE: To study the change rules of specific leaf weight, dry weight of rhizoma and the drying rate of annual and biennial Atractylodes macrocephala.METHODS: We measured the specific leaf weight and dry weight of rhizoma, and accounted the drying rate and correlation by dugging the annual and biennial plants each 1... | ['Atractylodes', 'Biomass', 'Photosynthesis', 'Plant Leaves', 'Plants, Medicinal', 'Quality Control', 'Rhizome', 'Seasons', 'Sunlight'] | 19,873,724 | [['B01.650.940.800.575.912.250.100.126'], ['G16.500.275.157.100', 'N06.230.124.100'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.568'], ['A18.024.812'], ['B01.650.560'], ['J01.897.608'], ['A18.024.937.750', 'A18.400.750'], ['G01.910.645.661', 'G16.500.275.071... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Equivalence of students' scores on timed and untimed anatomy practical examinations. | Untimed examinations are popular with students because there is a perception that first impressions may be incorrect, and that difficult questions require more time for reflection. In this report, we tested the hypothesis that timed anatomy practical examinations are inherently more difficult than untimed examinations.... | ['Anatomy', 'Comprehension', 'Educational Measurement', 'Female', 'Humans', 'Male', 'Perception', 'Philadelphia', 'Physical Therapy Specialty', 'Stress, Psychological', 'Students, Health Occupations', 'Task Performance and Analysis', 'Time Factors', 'Universities', 'Young Adult'] | 23,463,722 | [['H01.158.100'], ['F02.463.188.357'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593'], ['Z01.107.567.875.500.550.525', 'Z01.433.820'], ['H02.010.625'], ['F01.145.126.990', 'F02.830.900'], ['M01.848.769'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600'], ['G01.910.857'], ['I02.783.83... | ['Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 |
Neuroprotective properties of gallic acid from Sanguisorbae radix on amyloid beta protein (25--35)-induced toxicity in cultured rat cortical neurons. | Our previous studies reported that methanol extract of Sanguisorbae radix from Sanguisorba officinalis L. (Rosaceae) prevented neuronal cell damage induced by Abeta (25-35) in vitro. The present study was carried out to investigate the effect of gallic acid isolated from Sanguisorbae radix on Abeta (25-35)-induced neur... | ['Amyloid beta-Peptides', 'Animals', 'Apoptosis', 'Calcium', 'Cells, Cultured', 'Cerebral Cortex', 'Female', 'Gallic Acid', 'Glutamic Acid', 'Neuroprotective Agents', 'Peptide Fragments', 'Rats', 'Rats, Sprague-Dawley', 'Reactive Oxygen Species', 'Sanguisorba'] | 18,175,960 | [['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['G04.146.954.035'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251'], ['A08.186.211.200.885.287.500'], ['D02.241.223.100.300.200', 'D02.241.511.390.200', 'D02.455.426.559.389.127.281.200', 'D02.455.426.559.389.657.410.20... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
N-sulfonylanthranilic acid derivatives as allosteric inhibitors of dengue viral RNA-dependent RNA polymerase. | A novel class of compounds containing N-sulfonylanthranilic acid was found to specifically inhibit dengue viral polymerase. The structural requirements for inhibition and a preliminary structure-activity relationship are described. A UV cross-linking experiment was used to map the allosteric binding site of the compoun... | ['Binding Sites', 'Dengue Virus', 'Enzyme Inhibitors', 'Humans', 'Inhibitory Concentration 50', 'Models, Molecular', 'RNA-Dependent RNA Polymerase', 'Structure-Activity Relationship', 'Sulfinic Acids', 'ortho-Aminobenzoates'] | 20,014,868 | [['G02.111.570.120'], ['B04.820.578.344.350.270'], ['D27.505.519.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.940.350', 'G07.690.936.563'], ['E05.599.595'], ['D08.811.913.696.445.735.780'], ['G02.111.830', 'G07.690.773.997'], ['D01.029.260.877.700', 'D01.875.800.700', 'D02.886.645.585'], ['D02.241.223.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Beyond the Individual: Social and Cultural Influences on the Health-Seeking Behaviors of African American Men. | Morbidity and mortality rates are alarmingly high among African American men and are influenced by the health-seeking behaviors of this population. This study examined data from 40 focus groups with African American men in Durham, North Carolina, to better understand social and cultural influences on health-seeking beh... | ['Adult', 'African Americans', 'Aged', 'Cultural Characteristics', 'Focus Groups', 'Humans', 'Male', "Men's Health", 'Middle Aged', 'Motivation', 'North Carolina', 'Patient Acceptance of Health Care', 'Peer Group', 'Socioeconomic Factors'] | 30,767,594 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['I01.076.201.450.324', 'I01.880.853.100.329'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.400.425'], ['M01.060.116.630'], ['F01.658', 'F01.752.543.500.750'],... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Esthesioneuroblastoma as an unusual cause for dystopia. | Abstract Esthesioneuroblastoma, also known as olfactory neuroblastoma, is an uncommon malignant neoplasm arising from the olfactory epithelium in the roof of the nasal cavity. There are very few case reports published worldwide. The common presenting symptoms of Esthesioneuroblastoma are unilateral nasal obstruction (7... | ['Combined Modality Therapy', 'Craniotomy', 'Diagnosis, Differential', 'Esthesioneuroblastoma, Olfactory', 'Exophthalmos', 'Eye Abnormalities', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Nasal Cavity', 'Nose Neoplasms', 'Orbit', 'Tomography, X-Ray Computed', 'Young Adult'] | 24,063,411 | [['E02.186'], ['E04.525.190'], ['E01.171'], ['C04.557.465.625.600.590.650.550.150', 'C04.557.470.670.590.650.550.150', 'C04.557.580.625.600.590.650.550.150', 'C10.292.650.200'], ['C11.675.349'], ['C11.250', 'C16.131.384'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A04.531.449'], ['C04.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Snout contact fixation, climbing and gnawing during apomorphine stereotypy in rats from two substrains. | Apomorphine, at doses greater than or equal to 10 mg/kg (intraperitoneally), produced two patterns of stereotypy. In rats from one supplier it induced predominantly gnawing while in those from another predominantly climbing, suggesting that the response to the drug is influenced by genetic and/or experimental factors. ... | ['Animals', 'Apomorphine', 'Behavior, Animal', 'Dose-Response Relationship, Drug', 'Humans', 'Male', 'Motor Activity', 'Rats', 'Rats, Inbred Strains', 'Species Specificity', 'Stereotyped Behavior'] | 7,201,932 | [['B01.050'], ['D03.132.098.038.290', 'D03.633.100.531.085.030.290', 'D03.633.400.095.290'], ['F01.145.113'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', 'G11.427.410.698'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Singlet CH domain containing human multidomain proteins: an inventory. | The actin cytoskeleton presents the basic force in processes such as cytokinesis, endocytosis, vesicular trafficking and cell migration. Here, we list 30 human singlet CH (calpononin homology/actin binding) containing multidomain molecules, each encoded by one gene. We show the domain distributions as given by the SMAR... | ['Amino Acid Sequence', 'Calcium-Binding Proteins', 'Evolution, Molecular', 'Gene Components', 'Humans', 'Microfilament Proteins', 'Molecular Sequence Data', 'Multigene Family', 'Phylogeny', 'Protein Structure, Tertiary', 'Sequence Alignment'] | 19,459,066 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.157.125'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.024.340.137'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.730', 'D12.776.220.525'], ['L01.453.245.667'], ['G05.360.340.024.340.645'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G02.111.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Of Asian forests and European fields: Eastern U.S. plant invasions in a global floristic context. | BACKGROUND: Biogeographic patterns of species invasions hold important clues to solving the recalcitrant 'who', 'where', and 'why' questions of invasion biology, but the few existing studies make no attempt to distinguish alien floras (all non-native occurrences) from invasive floras (rapidly spreading species of signi... | ['Acclimatization', 'Agriculture', 'Asia', 'Databases, Factual', 'Ecosystem', 'Environment', 'Europe', 'Flowers', 'Geography', 'Models, Biological', 'Movement', 'Plant Physiological Phenomena', 'Plants', 'Trees', 'United States'] | 18,978,940 | [['G07.025.133', 'G16.012.500.133'], ['J01.040'], ['Z01.252'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['G16.500.275.157', 'N06.230.124'], ['G16.500.275', 'N06.230'], ['Z01.542'], ['A18.024.249.500'], ['H01.277.500'], ['E05.599.395'], ['G07.568', 'G11.427.410'], ['G15'], ['B01.650'], ['B01.650.915'], ['Z01.... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Information Science [L]', 'Health Care [N]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
Studies on the allergenicity of the developing spores of Pteris vittata L. | Ninety patients were investigated with intradermal testing of developing stages of Pteris vittata L., whole spores, and their fractions. Allergenic principles were found to be present in both protoplasm and spore wall of the fertile tissue. | ['Adolescent', 'Adult', 'Allergens', 'Animals', 'Female', 'Humans', 'Hypersensitivity', 'Intradermal Tests', 'Male', 'Microscopy, Electron, Scanning', 'Middle Aged', 'Plant Proteins', 'Plants', 'Rats', 'Rats, Inbred Strains', 'Skin', 'Spores'] | 2,774,307 | [['M01.060.057'], ['M01.060.116'], ['D23.050.063'], ['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['E01.370.225.812.871.300', 'E05.200.812.871.300', 'E05.478.594.890.300'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['M01.060.116.630'], ['D12.776.765'], ['B01.650'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Use of powder metallurgy for development of implants of Co-Cr-Mo alloy powder]. | This paper discusses the application of powder metallurgy for the development of porous implantation materials. Powders obtained from Co-Cr-Mo alloy with different carbon content by water spraying and grinding, have been investigated. Cold pressing and rotary re-pressing methods were used for compressing the powder. It... | ['Humans', 'Metallurgy', 'Microscopy, Electron, Scanning', 'Powders', 'Prostheses and Implants', 'Surface Properties', 'Vitallium'] | 11,388,037 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576.655.875.400'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D26.255.779'], ['E07.695'], ['G02.860'], ['D01.220.175.950', 'D01.552.033.182.900', 'D25.058.224.735', 'D25.339.208.224.959', 'J01.637.051.058.224.735', 'J01.637.051.339.208.224.959']] | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Ultrasound controlled follicle puncture in the "2 instrument technic"]. | The authors present a new instrumentarium for ultrasonically guided transabdominal-transvesical follicular puncture. Permanent sonographic imaging of the puncture cannula and precise puncturing without being impeded by the resistance of the abdominal wall are provided by an attachment functioning as an adjustable targe... | ['Embryo Transfer', 'Female', 'Fertilization in Vitro', 'Humans', 'Laparoscopes', 'Ovarian Follicle', 'Pregnancy', 'Ultrasonography'] | 2,947,326 | [['E02.875.800.500', 'E05.820.800.500'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.230.220.520', 'E07.858.240.520'], ['A05.360.319.114.630.535', 'A06.300.312.497.535'], ['G08.686.784.769'], ['E01.370.350.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Overdiagnosis, sojourn time, and sensitivity in the Copenhagen mammography screening program. | The goal of this research was to estimate the overdiagnosis at the first and second screens of the mammography screening program in Copenhagen, Denmark. This study involves a mammography service screening program in Copenhagen, Denmark, with 35,123 women screened at least once. We fit multistate models to the screening... | ['Aged', 'Breast Neoplasms', 'Denmark', 'Disease Progression', 'Female', 'Humans', 'Mammography', 'Mass Screening', 'Middle Aged', 'Models, Theoretical', 'Sensitivity and Specificity'] | 16,848,843 | [['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['Z01.542.816.124'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500']... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Functional divergence prediction from evolutionary analysis: a case study of vertebrate hemoglobin. | It is a central assumption of evolution that gene duplications provide the genetic raw material from which to create proteins with new functions. The increasing availability in multigene family sequences that has resulted from genome projects has inspired the creation of novel in silico approaches to predict details of... | ['Animals', 'Binding Sites', 'Databases, Genetic', 'Evolution, Molecular', 'Genome', 'Hemoglobins', 'Humans', 'Models, Molecular', 'Multigene Family', 'Oxygen', 'Phylogeny', 'Protein Conformation', 'Software'] | 12,832,652 | [['B01.050'], ['G02.111.570.120'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['G05.045.250', 'G16.075.250'], ['G05.360.340'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595'], ['G05.360.340.024.340.645'], ['D01.268.185.550', 'D01.362.670'], [... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Closure of Myelomeningocele Within 48 Hours to Decrease Infection Risk. | BACKGROUND: Appropriate timing for closure of myelomeningocele (MM) varies in the literature. Older studies present 48 h as the timeframe after which infection complication rates rise.OBJECTIVE: The objective of this guideline is to determine if closing the MM within 48 h decreases the risk of wound infection or ventri... | ['Cerebral Ventriculitis', 'Humans', 'Meningomyelocele', 'Neurosurgical Procedures', 'Surgical Wound Infection', 'Time Factors'] | 31,418,041 | [['C01.207.245.169', 'C10.228.140.430.249', 'C10.228.228.245.169'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.500.680.610', 'C16.131.666.680.610'], ['E04.525'], ['C01.947.692', 'C23.550.767.925'], ['G01.910.857']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Avoiding premature closure in sequential diagnosis. | An important aspect of diagnostic reasoning is the ability to recognise when there is sufficient evidence to enable a working diagnosis to be made and thus avoid the unnecessary risks and costs of further testing. On the other hand, the reasoner must be careful to avoid the error, known as premature closure, of accepti... | ['Abdomen, Acute', 'Adult', 'Age Factors', 'Aged', 'Artificial Intelligence', 'Child', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Models, Theoretical', 'Probability', 'Sex Factors'] | 9,232,189 | [['C23.888.592.612.054.200', 'C23.888.821.030.249'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['G17.035.250', 'L01.224.050.375'], ['M01.060.406'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.85... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Responses of neurons of the upper cervical segments of the spinal cord in the cat to stimulation of the locomotor region of the brain stem with different frequencies]. | Synaptic responses of C2 and C3 neurons to stimulation of medullary or midbrain locomotor points were recorded extracellularly in mesencephalic cats. Neurons excited with a firing index of 0.4-0.6 at a stimulation frequency of 2 S-1 retained this index at frequencies of 20-60 S-1 too. Many neurons with the low firing i... | ['Animals', 'Brain Mapping', 'Cats', 'Decerebrate State', 'Electric Stimulation', 'Locomotion', 'Medulla Oblongata', 'Reaction Time', 'Spinal Cord', 'Synapses'] | 6,621,743 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C10.597.305', 'C23.888.592.298'], ['E05.723.402'], ['G07.568.500', 'G11.427.410.568'], ['A08.186.211.132.810.591.500'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677']... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of fast food meals on nutrient intake of two groups. | Two groups in different population centers were studied to determine how often consumers frequented fast food restaurants, and consequently, how heavily they relied on this type of food for nutrients. A questionnaire was answered by 280 customers of two fast food restaurants of the same chain. They were asked how often... | ['Adolescent', 'Adult', 'Aged', 'Ascorbic Acid', 'Calcium, Dietary', 'Child', 'Child, Preschool', 'Diet', 'Dietary Fats', 'Dietary Proteins', 'Energy Intake', 'Feeding Behavior', 'Female', 'Humans', 'Infant', 'Iron', 'Male', 'Middle Aged', 'Nutritional Requirements', 'Restaurants', 'Thiamine', 'Vitamin A'] | 845,349 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['D01.146.395'], ['M01.060.406'], ['M01.060.406.448'], ['G07.203.650.240'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.650.240.340']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
An anatomical method for re-siting the umbilicus. | The umbilicus is the only normal scar on the body and it is the most noticeable scar following abdominoplasty and TRAM or DIEP flap procedures. We describe a technique for resiting the umbilicus that attempts to recreate the anatomical structure by attaching the superficial fascia to the periumbilical skin to produce a... | ['Cosmetic Techniques', 'Humans', 'Umbilicus'] | 15,253,213 | [['E02.218'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.923.047.849']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Technetium-99m methoxyisobutylisonitrile chest imaging for small-cell lung cancer. Relationship to chemotherapy response (six courses of combination of cisplatin and etoposide) and p-glycoprotein or multidrug resistance related protein expression. | AIMS: This is a retrospective and adaptive randomization study. The purpose of this study was to evaluate the relationship between technetium-99m methoxyisobutylisonitrile (Tc-99m MIBI) chest-imaging results, chemotherapy response and P-glycoprotein (Pgp) or multidrug resistance related protein (MRP) expression in smal... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma, Small Cell', 'Cisplatin', 'Etoposide', 'Female', 'Humans', 'Immunoenzyme Techniques', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Multidrug Resistance-Associated Proteins', 'Prognosis', 'Radio... | 11,822,755 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.557.470.200.380'], ['... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Use of a human skin in vitro model to investigate the influence of 'every-day' clothing and skin surface decontamination on the percutaneous penetration of organophosphates. | UNLABELLED: Organophosphates (OPs) are widely used in agriculture. Many studies have investigated the capability of personal protective equipment (PPE) to reduce chemical exposure; however, investigations into the protective effect of 'every-day' clothing are rare. The purpose of this study was to investigate the prote... | ['2-Propanol', 'Chlorpyrifos', 'Clothing', 'Decontamination', 'Dichlorvos', 'Female', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'In Vitro Techniques', 'Motor Vehicles', 'Occupational Exposure', 'Organophosphorus Compounds', 'Propylene Glycol', 'Skin', 'Skin Absorption', 'Solvents'] | 24,910,987 | [['D02.033.755.615'], ['D02.705.400.625.100', 'D02.705.539.345.100', 'D02.886.300.692.100'], ['J01.637.215'], ['N06.850.780.325'], ['D02.705.400.130'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['J01.937.500'], ['N06.850.460.350.600'], ['D02.705'], ['D02.0... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[The effect of temperature on the motor activity of the chick embryo and amnion at 5-14 days of development]. | It has been shown that cooling the developing eggs from 37.7 degrees C results cessation of motor activity of the amnion in 5-14-day embryos at 36-33 degrees C, whereas motor activity of the embryo remains unaffected up to 31-26 degrees C. Immobilization of the embryo was observed on cooling up to 22-18 degrees C. The ... | ['Amnion', 'Animals', 'Chick Embryo', 'Cold Temperature', 'Hot Temperature', 'Motor Activity', 'Temperature', 'Time Factors'] | 1,817,418 | [['A10.615.284.277', 'A16.254.750.277'], ['B01.050'], ['A13.350.150', 'A16.331.200'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.72... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Papillary carcinoma of the thyroid gland]. | Papillary thyroid cancer is after ovarian cancer the most frequent malignant disease of the endocrine system and because of this fact, early detection and appropriate surgical treatment is essential. Radical surgical treatment lower the risk of the disease relapse and postoperative adjuvant therapy with radioiodine is ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Papillary', 'Child', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Thyroid Neoplasms', 'Thyroidectomy'] | 15,179,760 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.5... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Massively parallel sequencing analysis of nondegraded and degraded DNA mixtures using the ForenSeq™ system in combination with EuroForMix software. | Massively parallel sequencing (MPS) technologies enable the simultaneous analysis of short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs). MPS also enables the detection of alleles of the minor contributors in imbalanced DNA mixtures. In this study, 59 STRs (amelogenin, 27 autosomal STRs, 7 X-STRs, an... | ['Asian Continental Ancestry Group', 'DNA Degradation, Necrotic', 'DNA Fingerprinting', 'Female', 'Gene Frequency', 'Genotype', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Likelihood Functions', 'Male', 'Microsatellite Repeats', 'Polymorphism, Single Nucleotide', 'Sequence Analysis, DNA', 'Software'] | 30,374,565 | [['M01.686.508.200'], ['C23.550.717.273', 'G05.200.220'], ['E05.318.740.225.500.500', 'E05.393.290', 'I01.198.780.937.375', 'N04.452.910.099.750'], ['G05.330'], ['G05.380'], ['E05.393.760.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.3... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Factors influencing the complication rate of subduroperitoneal shunt placement for the treatment of subdural hematomas in infants. | OBJECT: In this study the authors' goal was to identify the complication rate of subduroperitoneal (SDP) shunts for the treatment of subdural hematomas (SDHs) in infants and to determine the influences on and predictive factors for these complications.METHODS: The authors present a case series spanning the years 1994 t... | ['Device Removal', 'Drainage', 'Female', 'Follow-Up Studies', 'Hematoma, Subdural, Intracranial', 'Humans', 'Infant', 'Male', 'Retrospective Studies', 'Risk Factors', 'Treatment Outcome', 'Ventriculoperitoneal Shunt'] | 17,465,380 | [['E04.199'], ['E02.309', 'E04.237'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C10.228.140.300.535.450.400.400', 'C10.900.300.837.600.400', 'C14.907.253.573.400.450.400', 'C23.550.414.838.700.400', 'C23.550.414.913.700.400', 'C26.915.300.490.450.400'], ['B01.050.150.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Potential use of high levels of vegetal proteins in diets for market-sized gilthead sea bream (Sparus aurata). | The effect of partial or total dietary substitution of fishmeal (FM) by vegetal protein sources on growth and feed efficiency was carried out in on-growing gilthead sea bream (mean initial weight 131 g). The Control diet (FM 100) contained FM as the primary protein source, while in Diets FM 25 and FM 0 the FM protein w... | ['Amino Acids', 'Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Aquaculture', 'Body Weight', 'Diet', 'Digestion', 'Fish Products', 'Plant Proteins', 'Sea Bream'] | 26,880,503 | [['D12.125'], ['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['J01.040.168'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G07.203.650.240'], ['G07.203.650.250', 'G10.261.190'], ['G07.203.300.600.875.400', 'J02.500.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Chromosome number of Severtzov's sheep (Ovis ammon severtzovi): G-banded karyotype comparisons within ovis. | Severtzov's sheep (Ovis ammon severtzovi; Nasonov 1914) has a 2n = 56 diploid chromosome number and a karyotype consisting of two pairs of biarmed and 25 pairs of acrocentric autosomes, a large acrocentric X, and a minute biarmed Y. The G-banding patterns of the largest pair of biarmed chromosomes were identical to tho... | ['Animals', 'Animals, Wild', 'Chromosome Banding', 'Karyotyping', 'Male', 'Sheep', 'Species Specificity'] | 9,656,470 | [['B01.050'], ['B01.050.050.300'], ['E01.370.225.500.385.130', 'E01.370.225.500.620.670.130', 'E01.370.225.750.600.670.130', 'E05.200.500.385.130', 'E05.200.500.620.670.130', 'E05.200.750.600.670.130', 'E05.242.385.130', 'E05.393.285.130'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Energetics and metabolite profiles during early flight in American robins (Turdus Migratorius). | Although birds use fat as the primary fuel for migratory flights, carbohydrate and protein catabolism could be significant in the early stages of flight while pathways of fatty acid transport and oxidation are induced. The fuel mixture of long distance migrant birds can also be affected by the rate of water loss, where... | ['Animals', 'Blood Glucose', 'Body Composition', 'Butyrates', 'Energy Metabolism', 'Flight, Animal', 'Glycerol', 'Hematocrit', 'Humidity', 'Phospholipids', 'Proteins', 'Songbirds', 'Triglycerides', 'Uric Acid'] | 23,715,798 | [['B01.050'], ['D09.947.875.359.448.500'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['D02.241.081.114', 'D10.251.400.143'], ['G03.295'], ['G11.427.410.568.304', 'G11.427.410.698.416'], ['D02.033.800.875.500', 'D09.853.875.500'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['G16.500.275.063.725.310'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Capping structures of simian virus 40 19S and 16S mRNAs. | In vivo [methyl 3H]-labeled SV40 19S and 16S mRNA species were purified and their internal methylation as well as their capping structures analyzed. SV40 viral mRNA sedimenting in the 19S region contains approximately equal proportions of m7GpppAm and m7Gppm6Am, while the 16S mRNA contains mainly m7Gpppm6Am. N6 methyl ... | ['Adenosine', 'Base Sequence', 'Guanosine', 'Methylation', 'Molecular Weight', 'RNA, Messenger', 'RNA, Viral', 'Simian virus 40'] | 201,923 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D03.633.100.759.590.454', 'D13.570.583.454', 'D13.570.800.453'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['G02.494'], ['D13.444.735.544'], ['D13.444.735.828'], ['B04.280.210.70... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Synchrotron radiation circular dichroism spectroscopy reveals structural divergences in HDL-bound apoA-I variants. | Apolipoprotein A-I (apoA-I) in high-density lipoprotein (HDL) provides cardiovascular protection. Synchrotron radiation circular dichroism (SRCD) spectroscopy was used to analyze the dynamic solution structure of the apoA-I protein in the apo- and HDL-states and the protein structure conversion in HDL formation. Wild-t... | ['Apolipoprotein A-I', 'Circular Dichroism', 'Humans', 'Lipoproteins, HDL', 'Polymorphism, Single Nucleotide', 'Protein Binding', 'Protein Conformation, beta-Strand', 'Protein Stability', 'Synchrotrons', 'Transition Temperature'] | 29,051,568 | [['D10.532.091.200.100', 'D12.776.070.400.200.100', 'D12.776.521.120.200.100'], ['E05.196.867.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.532.432', 'D12.776.521.479'], ['G05.365.795.598'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.600.750'], ['G02.111.700'], ['E07.710.680.700'], ['G01.906.595.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Strategies to improve the fertility of fresh and frozen donkey semen. | Fertility rates of donkey semen in jennies are lower compared to mares. The aims of this study were to evaluate different sperm cryopreservation methods and insemination strategies to improve the fertility of donkey semen in jennies. Three experiments were performed: (1) the comparison of two freezing methods of donkey... | ['Animals', 'Cryopreservation', 'Equidae', 'Female', 'Fertility', 'Freezing', 'Insemination, Artificial', 'Male', 'Pregnancy', 'Semen Preservation'] | 26,806,444 | [['B01.050'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['B01.050.150.900.649.313.984.235'], ['G08.686.210'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['E02.875.800.937', 'E05.820.800.937', 'G08.686.7... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acceptance, attitudes, and beliefs of Singaporean Chinese toward an ocular implant for glaucoma drug delivery. | PURPOSE: We investigated patients' attitudes and perceptions toward a subconjunctival implant as a novel ocular drug delivery method for glaucoma.METHODS: We recruited 344 Chinese patients with primary open angle or angle closure glaucoma currently on topical antiglaucoma medication for a minimum of six months from spe... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antihypertensive Agents', 'Asian Continental Ancestry Group', 'Attitude to Health', 'Cross-Sectional Studies', 'Drug Delivery Systems', 'Drug Implants', 'Female', 'Glaucoma, Angle-Closure', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Male', 'Medication Adherence', ... | 23,188,725 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.411.162'], ['M01.686.508.200'], ['F01.100.150', 'N05.300.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E02.319.300'], ['D26.255.210.315'], ['C11.525.381.056'], ['C11.525.381.407'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Characteristics of aldehyde dehydrogenases of certain aerobic bacteria representing human colonic flora. | We have proposed the existence of a bacteriocolonic pathway for ethanol oxidation resulting in high intracolonic levels of toxic and carcinogenic acetaldehyde. This study was aimed at determining the ability of the aldehyde dehydrogenases (ALDH) of aerobic bacteria representing human colonic flora to metabolize intraco... | ['Acetaldehyde', 'Alcohol Drinking', 'Aldehyde Dehydrogenase', 'Colon', 'Escherichia coli', 'Ethanol', 'Humans', 'Intestinal Mucosa', 'Klebsiella pneumoniae', 'Pseudomonas aeruginosa', 'Risk Factors'] | 9,632,053 | [['D02.047.064'], ['F01.145.317.269'], ['D08.811.682.657.163.249'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.369', 'A10.615.550.444'], ['B03.440.450.425.425.600', 'B03.660.250.1... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Long-term prognostic significance of homocysteine in middle-aged and elderly. | OBJECTIVE: We investigated the association among increased levels of plasma homocysteine (Hcy), all-cause mortality, and cardiovascular events.METHODS: Hcy was measured in 670 middle-aged and elderly subjects with no previous manifest cardiovascular disease. The follow-up period was 15 years.RESULTS: Subjects with Hcy ... | ['Aged', 'Biomarkers', 'Cardiovascular Diseases', 'Disease-Free Survival', 'Female', 'Follow-Up Studies', 'Homocysteine', 'Humans', 'Incidence', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Prognosis', 'Proportional Hazards Models', 'Risk Factors'] | 27,008,914 | [['M01.060.116.100'], ['D23.101'], ['C14'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D02.886.030.498', 'D12.125.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Oxidation of reduced nicotinamide adenine dinucleotide by particles from Mycobacterium lepraemurium. | Particles from Mycobacterium lepraemurium catalysed the oxidation of NADH with oxygen as the terminal electron acceptor. The preparations contained cytochromes of the a + a3'b and c types, as well as CO-binding pigments. The NADH oxidase activity was sensitive to inhibitors of the flavoprotein system as well as to HQNO... | ['Amobarbital', 'Antimycin A', 'Azides', 'Carbon Monoxide', 'Cell-Free System', 'Chloromercuribenzoates', 'Cyanides', 'Cytochromes', 'Dinitrophenols', 'Kinetics', 'Mycobacterium lepraemurium', 'NAD', 'NADH, NADPH Oxidoreductases', 'Oxygen Consumption', 'Pentachlorophenol', 'Pigments, Biological', 'Quinacrine', 'Quinoli... | 170,040 | [['D03.383.742.698.253.077'], ['D02.540.576.500.750'], ['D01.625.100', 'D02.159'], ['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['A11.284.835.168'], ['D02.241.223.100.200.311', 'D02.241.223.100.500.261', 'D02.455.426.559.389.127.250.311', 'D02.455.426.559.389.127.500.261', 'D02.691.750.740.644.261'], ['D01.248.49... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The medical mall design as an answer to hospital cost control. | Reorganizing the hospital's inpatient and outpatient services for the convenience of patients and to decrease acute care costs is becoming a necessary strategy under prospective pricing. Two architectural planners discuss the health care mall concept and the benefits of segregating ambulatory and ancillary services. | ['Facility Design and Construction', 'Health Facilities', 'Health Services Accessibility', 'Medical Office Buildings', 'United States'] | 10,270,506 | [['J01.086.339', 'N02.278.200'], ['N02.278'], ['N04.590.374.350', 'N05.300.430'], ['N02.278.562'], ['Z01.107.567.875']] | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
[Clinical pharmacokinetics of the antitumor antibiotic reumycin: an analysis of individual variability]. | The pharmacokinetics of reumycin, an antitumor antibiotic, was studied with high performance liquid chromatography in patients with tumors of the brain and kidneys. The drug was injected intravenously in single doses of 30-300 mg. It was shown that the pharmacokinetics of reumycin was nonlinear and within every dose co... | ['Antibiotics, Antineoplastic', 'Brain Neoplasms', 'Chromatography, High Pressure Liquid', 'Humans', 'Kidney Neoplasms', 'Kinetics', 'Neoplasm Metastasis', 'Time Factors', 'Triazines'] | 4,062,279 | [['D27.505.954.248.106'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['G01.374.661', 'G02.111.490'], ['C04.697.650', ... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hemiepiphysiodesis for posttraumatic tibial valgus. | Posttraumatic tibial valgus is a recognized complication of proximal tibial metaphyseal fractures in children. There is no consensus regarding management of this malalignment; approaches range from repeated osteotomy to therapeutic nihilism. The authors present 12 patients with an average age at fracture of 4 years 11 ... | ['Bone Plates', 'Child', 'Child, Preschool', 'Epiphyses', 'Female', 'Fracture Fixation, Internal', 'Humans', 'Infant', 'Joint Deformities, Acquired', 'Knee Injuries', 'Male', 'Sutures', 'Tibia', 'Tibial Fractures', 'Treatment Outcome'] | 16,670,554 | [['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['M01.060.406'], ['M01.060.406.448'], ['A02.835.232.251'], ['E04.555.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C05.550.515'], ['C26.558.554'], ['E07.858.690.820'], ['A02.835.232.043.650.883'], ['C26.404.875'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The yajC gene from Lactobacillus buchneri and Escherichia coli and its role in ethanol tolerance. | The yajC gene (Lbuc_0921) from Lactobacillus buchneri NRRL B-30929 was identified from previous proteomics analyses in response to ethanol treatment. The YajC protein expression was increased by 15-fold in response to 10 % ethanol vs 0 % ethanol. The yajC gene encodes the smaller subunit of the preprotein translocase c... | ['Bacterial Proteins', 'Cell Membrane', 'Escherichia coli', 'Escherichia coli Proteins', 'Ethanol', 'Genes, Bacterial', 'Lactobacillus', 'Protein Transport', 'SEC Translocation Channels', 'Stress, Physiological'] | 26,790,414 | [['D12.776.097'], ['A11.284.149'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['D02.033.375'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.550.450.475'], ['G03.143.700'], ['D05.50... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structure and antibacterial property of a new diterpenoid from Euphorbia helioscopia. | The present study was designed to isolate and evaluate the antibacterial activity of the compounds from the whole plant of Euphorbia helioscopia L.. Various chromatographic techniques were used to isolate and purify the compound. The structure of the compound was elucidated on basis of spectral data ((1)H NMR, (13)C NM... | ['Anti-Infective Agents', 'Diterpenes', 'Euphorbia', 'Molecular Structure', 'Mouth Diseases', 'Niacin', 'Plant Extracts'] | 26,412,431 | [['D27.505.954.122'], ['D02.455.849.291'], ['B01.650.940.800.575.912.250.859.797.438.333'], ['G02.111.570', 'G02.466'], ['C07.465'], ['D03.066.515.475', 'D03.383.725.547.475'], ['D20.215.784.500', 'D26.667']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A new strategy for the combination of supramolecular liquid phase microextraction and UV-Vis spectrophotometric determination for traces of maneb in food and water samples. | A novel and green method was developed for enrichment of maneb (manganese ethylene-bisdithiocarbamate) with a supramolecular solvent liquid phase microextraction method. The microextraction method has been used for the first time in the literature for separation-preconcentration of maneb. 1-decanol and tetrahydrofuran ... | ['Food Analysis', 'Furans', 'Hydrogen-Ion Concentration', 'Limit of Detection', 'Liquid Phase Microextraction', 'Maneb', 'Manganese', 'Naphthols', 'Solvents', 'Spectrophotometry', 'Water'] | 32,950,010 | [['E05.362', 'J01.576.423.850.100'], ['D03.383.312'], ['G02.300'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['E05.196.155.650.500'], ['D02.241.081.251.869.265.441', 'D02.257.188', 'D02.886.706.250.500'], ['D01.268.556.484', 'D01.268.956.374', 'D01.552.544.484'], ['D02.455.426.559.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Surface plasmon resonance characterization of calspermin-calmodulin binding kinetics. | We cloned, expressed, and purified a chimeric fusion between a soluble green fluorescent protein (smGFP) and the calmodulin binding protein calspermin. We have shown that the fusion protein, labeled smGN, has a K(i) in the calmodulin-dependent cyclic nucleotide phosphodiesterase activity assay of 1.97 nM, i.e., 3800 ti... | ['Animals', 'Arabidopsis Proteins', 'Binding Sites', 'Calmodulin', 'Calmodulin-Binding Proteins', 'Chromatography, Affinity', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Green Fluorescent Proteins', 'Kinetics', 'Models, Molecular', 'Protein Binding', 'Protein Structure, Secondary', 'Protein Structure, T... | 18,294,447 | [['B01.050'], ['D12.776.765.149'], ['G02.111.570.120'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['D12.776.157.142'], ['E05.196.181.400.170'], ['E05.196.401.402', 'E05.301.300.319'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.532.265'], ['G01.374.661', 'G02.111.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Factors associated with delirium severity among older patients. | AIM: The goal of this study was to determine whether the factors associated with delirium varied according to the severity of the delirium experienced by the older patients.BACKGROUND: Delirium among older patients is prevalent and leads to numerous detrimental effects. The negative consequences of delirium are worse a... | ['Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Causality', 'Cognition Disorders', 'Delirium', 'Female', 'Health Status', 'Humans', 'Long-Term Care', 'Male', 'Polypharmacy', 'Risk Factors', 'Severity of Illness Index'] | 17,462,033 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N05.715.350.200', 'N06.850.490.625'], ['F03.615.250'], ['C10.597.606.337.500', 'C23.888.592.604.339.500', 'F01.700.250.500', 'F03.615.350'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The Risk of Pyrrolizidine Alkaloids in Human Food and Animal Feed. | Toxicity from naturally occurring plant pyrrolizidine alkaloids bears substantial risk to humans and livestock. Risk management strategies must focus on minimizing the likelihood of such alkaloids entering into the food chain. To address this challenge, we describe the role of a tiered risk characterization approach an... | ['Animal Feed', 'Animals', 'Food Safety', 'Humans', 'Pyrrolizidine Alkaloids', 'Risk Management'] | 28,188,017 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['J01.576.423.850.730.500', 'N06.850.601.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.132.716', 'D03.633.100.772'], ['N03.219.463.800', 'N04.452.871']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Effects of isoflurane and sevoflurane on the survival of skin flaps in rats. | The effects of inhalational anaesthetic agents on survival of flaps are not well known. We investigated the effect of isoflurane and sevoflurane anaesthesia on survival of flaps using a caudally-based McFarlane skin flap in 20 male Wistar rats. Sevoflurane 1 minimum alveolar concentration (MAC) and isoflurane (1 MAC) i... | ['Anesthesia', 'Animals', 'Dermatologic Surgical Procedures', 'Graft Survival', 'Isoflurane', 'Male', 'Methyl Ethers', 'Models, Animal', 'Rats', 'Rats, Wistar', 'Sevoflurane', 'Skin', 'Skin Transplantation', 'Surgical Flaps'] | 16,320,401 | [['E03.155'], ['B01.050'], ['E04.680.275'], ['G12.875.545.340'], ['D02.355.601.570'], ['D02.355.601'], ['E05.598'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D02.355.601.810', 'D02.455.526.510.717'], ['A17.815'], ['E02.095.147.725.700', 'E04.680.275.850', 'E04.936.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Micromethod for plasminogen determination]. | Conditions are developed for determining potential activity of plasminogen in amine groups formed in casein hydrolysis. Two variants of determination are suggested: by means of a ninhydrin reagent and trinitrobenzene sulphoacid. The method permits determining 0.02-0.1 of plasmin casein units (cas. units); it is 20 time... | ['Caseins', 'Colorimetry', 'Humans', 'Indicators and Reagents', 'Kinetics', 'Microchemistry', 'Plasminogen'] | 7,324,197 | [['D12.776.256.159.750.207', 'D12.776.744.150'], ['E05.196.922.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.410'], ['G01.374.661', 'G02.111.490'], ['E05.196.620', 'H01.181.650'], ['D08.622.610', 'D12.776.124.790.223.580', 'D12.776.377.715.182.580', 'D12.776.811.243.610']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The nicotinic receptor agonists (-)-nicotine and isoarecolone differ in their effects on dopamine release in the nucleus accumbens. | This study compared the effect of the nicotinic receptor agonists, (-)-nicotine and isoarecolone, on the mesolimbic dopamine system of the rat using in vivo microdialysis. Previous studies showed that (-)-nicotine but not isoarecolone produced a locomotor activating effect, and that this was probably mediated by increa... | ['3,4-Dihydroxyphenylacetic Acid', 'Animals', 'Arecoline', 'Dopamine', 'Male', 'Nicotine', 'Nicotinic Agonists', 'Nucleus Accumbens', 'Rats', 'Rats, Sprague-Dawley', 'Time Factors'] | 8,720,585 | [['D02.241.223.601.220'], ['B01.050'], ['D03.066.515.292', 'D03.132.080', 'D03.383.725.547.292'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D03.132.760.570', 'D03.383.725.518'], ['D27.505.519.625.120.140.700', 'D27.505.696.577.120.140.700'], ['A08.186.211.200.885.287.249.487.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immune response of SLE patients to peptides based on the complementarity determining regions of a pathogenic anti-DNA monoclonal antibody. | We have examined the humoral and cellular responses of SLE patients to peptides based on the complementarity-determining regions (CDR) of a monoclonal anti-DNA antibody with a major idiotype- 16/6 Id, in comparison to their responses to the whole 16/6 Id-bearing antibody. Sera of 63% of the SLE patients had antibodies ... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Anti-Idiotypic', 'Antibodies, Antinuclear', 'Antibodies, Monoclonal', 'Case-Control Studies', 'Complementarity Determining Regions', 'Humans', 'Immunity, Cellular', 'Immunoglobulin Idiotypes', 'In Vitro Techniques', 'Lupus Erythematosus, Systemic', 'Lymphocyte Activation'... | 10,941,826 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.071', 'D12.776.124.790.651.114.071', 'D12.776.377.715.548.114.071'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Axial heterogeneity of adenosine transport and metabolism in the rabbit proximal tubule. | Transport and metabolism of adenosine were studied in the S1, S2, and S3 segments of the rabbit proximal renal tubule. Isolated segments were perfused in vitro with uniformly labelled 14C-adenosine to measure the lumen-to-bath flux of adenosine. This flux rate was measured by the disappearance of 14C from the luminal f... | ['Absorption', 'Adenosine', 'Animals', 'Biological Transport, Active', 'Chromatography, High Pressure Liquid', 'In Vitro Techniques', 'Kidney Tubules, Proximal', 'Kinetics', 'Perfusion', 'Rabbits'] | 1,614,030 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['B01.050'], ['G03.143.310'], ['E05.196.181.400.300'], ['E05.481'], ['A05.810.453.736.560.570'], ['G01.374.661', 'G02.111.490'], ['E05.680'], ['B01.050.150.900.649.313.968.700']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The metabolism of styrene oxide in the isolated perfused rat liver. Identification and quantitation of major metabolites. | Isolated perfused rat livers rapidly metabolized 14C-styrene oxide. A large proportion of the administered radioactivity was excreted in the bile as a single compound that was identified as S-(1-phenyl-2-hydroxyethyl)glutathione by comparison with an authentic synthetic standard. The circulating perfusate was found to ... | ['Animals', 'Bile', 'Biotransformation', 'Chromatography, Thin Layer', 'In Vitro Techniques', 'Liver', 'Male', 'Rats', 'Styrenes', 'Time Factors'] | 19,215 | [['B01.050'], ['A12.200.087'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['E05.196.181.400.537'], ['E05.481'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.700'], ['D02.455.426.559.389.150.750'], ['G01.910.857']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Telemedicine applied to Nephrology. Another form of consultation]. | UNLABELLED: In 2004, according to socio- demographic criteria and to the improvement in the welfare quality, we incorporated to the portfolio of services of our section a work tool that meant a novel technology; the "telemedicine". The Objective has been to asses the utility of telemedicine in the follow- up of the ren... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Kidney Diseases', 'Male', 'Middle Aged', 'Nephrology', 'Referral and Consultation', 'Retrospective Studies', 'Telemedicine', 'Young Adult'] | 18,662,148 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419', 'C13.351.968.419'], ['M01.060.116.630'], ['H02.403.429.580'], ['N04.452.758.849'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
NBP1 (Nap1 binding protein 1), an essential gene for G2/M transition of Saccharomyces cerevisiae, encodes a protein of distinct sub-nuclear localization. | Nap1p is identified in mammalian cell extract by its intrinsic activity to facilitate nucleosome assembly in vitro in the physiological ionic condition. The homologous proteins are present in most eukaryotes, and their functional analyses in vitro have suggested that they are necessary to keep proper nucleosome structu... | ['Amino Acid Sequence', 'Base Sequence', 'Carrier Proteins', 'Cell Cycle', 'Cell Cycle Proteins', 'Cell Division', 'Cell Nucleus', 'Cytoskeletal Proteins', 'DNA, Fungal', 'DNA-Binding Proteins', 'Fungal Proteins', 'G2 Phase', 'Genes, Essential', 'Green Fluorescent Proteins', 'Luminescent Proteins', 'Microscopy, Fluores... | 10,767,562 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.157'], ['G04.144'], ['D12.776.167'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D12.776.220'], ['D13.444.308.300'], ['D12... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Netilmicin in urinary tract infections. | 30 urological patients with normal renal function were treated with netilmicin because of urinary tract infections, mostly recurrent and due to predisposing factors. the drug was given in doses of 4 mg/kg/day for 4-9 days. All but 5 patients had resolution of their signs and symptoms, and the bacteria were eliminated i... | ['Adolescent', 'Adult', 'Aged', 'Enterobacteriaceae', 'Enterobacteriaceae Infections', 'Female', 'Gentamicins', 'Humans', 'Male', 'Microbial Sensitivity Tests', 'Middle Aged', 'Netilmicin', 'Pseudomonas Infections', 'Staphylococcal Infections', 'Streptococcal Infections', 'Urinary Tract Infections'] | 6,937,957 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B03.440.450.425', 'B03.660.250.150'], ['C01.150.252.400.310'], ['D09.408.051.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['M01.060.116.630'], ['D09.408.051.374.785.525'], ['C01.150.252.40... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Characteristics of surgically removed polyps in the course of follow-up after endoscopic polypectomy from the colon]. | Our experience refers to 188 patients submitted to endoscopic polypectomy, of whom 61 (32.4%) also to subsequent endoscopic controls. The polyps removed during follow-up compared to those previously removed showed the following characteristic: 1) Higher frequency in right colon (p > 0.01); 2) smaller size (p > 0.1); 3)... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Colonic Polyps', 'Colonoscopy', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged'] | 8,330,474 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['C23.300.825.411.235'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.85... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Alphoidless centromere of a familial unstable inverted Y chromosome. | We report on a 3-generation pedigree in which an inverted unstable Y chromosome had no phenotypical or reproductive repercussion despite a sizable proportion of secondary aneuploidies (mainly 45, X cells) in lymphocytes. This chromosome was metacentric and had a single Cd-positive primary constriction, but occasionally... | ['Adolescent', 'Aneuploidy', 'Centromere', 'Chromosome Inversion', 'DNA, Satellite', 'Humans', 'Male', 'Mitosis', 'Pedigree', 'Polymorphism, Genetic', 'Y Chromosome'] | 9,037,351 | [['M01.060.057'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['A11.284.430.106.279.345.190.160.165', 'G05.360.160.165'], ['C23.550.210.190', 'G05.365.590.175.190', 'G05.365.590.770.500', 'G05.558.805.500'], ['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.360.340.024.22... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Childhood trauma and health outcomes in HIV-infected patients: an exploration of causal pathways. | OBJECTIVE: Traumatic life histories are highly prevalent in people living with HIV/AIDS and predict sexual risk behaviors, medication adherence, and all-cause mortality. Yet the causal pathways explaining these relationships remain poorly understood. We sought to quantify the association of trauma with negative behavio... | ['Adaptation, Psychological', 'Female', 'HIV Infections', 'Homosexuality, Male', 'Humans', 'Life Change Events', 'Male', 'Patient Compliance', 'Social Support', 'Substance Abuse, Intravenous', 'Treatment Outcome', 'Unsafe Sex', 'Wounds and Injuries'] | 22,107,822 | [['F01.058'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['F01.145.802.975.500.600', 'G08.686.867.500.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458.410'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.... | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Canine myocilin is associated with lipid modified by palmitic acid. | PURPOSE: Myocilin, the product of the GLC1A locus in humans, has been associated with primary open angle glaucoma (POAG). Mutations in myocilin exon 3 correlate with age of onset and severity of POAG. Myocilin has been under investigation in experimentally induced glaucoma in rats, mice, and monkeys, however no animal ... | ['Amino Acid Sequence', 'Animals', 'Cell Line, Transformed', 'Cloning, Molecular', 'Cytoskeletal Proteins', 'Dogs', 'Eye', 'Eye Proteins', 'Gene Expression', 'Glycoproteins', 'Glycosylation', 'Lipid Metabolism', 'Molecular Sequence Data', 'Optic Disk', 'Palmitic Acid'] | 17,149,370 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.251.210.172'], ['E05.393.220'], ['D12.776.220'], ['B01.050.150.900.649.313.750.250.216.200'], ['A01.456.505.420', 'A09.371'], ['D12.776.306'], ['G05.297'], ['D09.400.430', 'D12.776.395'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['G03.458'], ['L0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The era of ultrasonography during laparoscopic cholecystectomy. | BACKGROUND: The use of ultrasound cholangiography during cholecystectomy has been well described. This study was undertaken to assess the use of the umbilical port exclusively for ultrasound and to assess its employment on the use of fluoroscopy resources. In addition, we also looked at the increased use of ultrasound ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cholecystectomy, Laparoscopic', 'Endosonography', 'Female', 'Fluoroscopy', 'Gallbladder Diseases', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Retrospective Studies', 'Umbilicus'] | 15,792,767 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.210.120.172.140', 'E04.502.250.520.160'], ['E01.370.350.850.280'], ['E01.370.350.700.225'], ['C06.130.564'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A rural local health department-hospital collaborative for a countywide community health assessment. | In mid-2012, the Polk County Health Department initiated a community health needs assessment process with the 3 medical centers serving this rural Wisconsin county of 45 000 residents. The collaborative process drew on primary and secondary data, including clinical data pooled from health care organizations, to assess ... | ['Cooperative Behavior', 'Health Services Accessibility', 'Humans', 'Needs Assessment', 'Public Health', 'Rural Population', 'Wisconsin'] | 25,414,952 | [['F01.145.813.115'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.594', 'N03.349.380.565', 'N05.300.537'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['N01.600.725'], ['Z01.107.567.875.350.900', 'Z01.107.567.875.510.900']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Fenvalerate-induced chromosome aberrations and sister chromatid exchanges in the bone marrow cells of mice in vivo. | Fenvalerate, a synthetic pyrethroid insecticide, is commonly used in agriculture and other domestic applications due to its high insecticidal activity and low mammalian-, avian- and phyto-toxicities. However, the genotoxic effect of fenvalerate is highly equivocal. In the present study the genotoxic effects of fenvaler... | ['Animals', 'Bone Marrow', 'Bone Marrow Cells', 'Chromosome Aberrations', 'Female', 'Insecticides', 'Male', 'Mice', 'Nitriles', 'Pyrethrins', 'Sister Chromatid Exchange'] | 12,297,152 | [['B01.050'], ['A15.382.216'], ['A11.148', 'A15.378.316'], ['C23.550.210', 'G05.365.590.175'], ['D27.720.031.700.491', 'D27.888.723.491'], ['B01.050.150.900.649.313.992.635.505.500'], ['D02.626'], ['D02.455.849.575.188.750'], ['G05.728.615.750']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcohol. | Here we report that low concentrations of alcohol (1-3 mM) increased Cl(-) currents gated by a recombinant GABA(A) receptor, alpha(4)beta(2)delta, by 40-50% in Xenopus laevis oocytes. We also found greater hippocampal expression of receptors containing alpha(4) and delta subunits, using a rat model of premenstrual synd... | ['Animals', 'Chlorides', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Ethanol', 'Female', 'Hippocampus', 'In Vitro Techniques', 'Ion Channel Gating', 'Oocytes', 'Patch-Clamp Techniques', 'Premenstrual Syndrome', 'Progesterone', 'Protein Subunits', 'RNA, Messenger', 'Rats', 'Receptors, GABA-A', 'Recomb... | 12,118,257 | [['B01.050'], ['D01.210.450.150', 'D01.248.497.158.215'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.033.375'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['E05.481'], ['G02.111.820.400', 'G04.835.400', 'G07.265.625'], ['A05.360.490.690.680', 'A11.497.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
T6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion. | Myosin VI has been implicated in many cellular processes including endocytosis, secretion, membrane ruffling and cell motility. We carried out a yeast two-hybrid screen and identified TRAF6-binding protein (T6BP) and nuclear dot protein 52 (NDP52) as myosin VI binding partners. Myosin VI interaction with T6BP and NDP52... | ['Actins', 'Alkaline Phosphatase', 'Binding Sites', 'Cell Adhesion', 'Cell Line', 'Cell Membrane', 'Cytokines', 'Cytoskeleton', 'Golgi Apparatus', 'HeLa Cells', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Metabolic Networks and Pathways', 'Microscopy, Electron, Transmission', 'Myosin Heavy Chains', 'NF-... | 17,635,994 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D08.811.277.352.650.035'], ['G02.111.570.120'], ['G04.022'], ['A11.251.210'], ['A11.284.149'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A11.284.430.214.190.750'], ['A11.284.430.214.190.875.336'], ['A11.251.210.190.400', 'A11.251.8... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Imaging and Genetic Approaches to Inform Biomarkers for Anxiety Disorders, Obsessive-Compulsive Disorders, and PSTD. | Anxiety disorders are the most common mental health problem in the world and also claim the highest health care cost among various neuropsychiatric disorders. Anxiety disorders have a chronic and recurrent course and cause significantly negative impacts on patients' social, personal, and occupational functioning as wel... | ['Anxiety', 'Anxiety Disorders', 'Biomarkers', 'Genetic Markers', 'Humans', 'Obsessive-Compulsive Disorder', 'Quality of Life', 'Stress Disorders, Post-Traumatic'] | 29,796,838 | [['F01.470.132'], ['F03.080'], ['D23.101'], ['D23.101.387', 'G05.695.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.080.600'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['F03.950.750.500']] | ['Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Agenesis of the gallbladder found at laparoscopy for cholecystectomy: an unpleasant surprise. | Gallbladder agenesis is a rare condition that results from the failure of the cystic bud to develop in the 4th wk of intrauterine life. Agenesis is usually discovered at laparotomy for cholecystectomy since ultrasound examination of a patient with suggestive symptoms not visualizing the gallbladder is compatible with c... | ['Cholecystectomy, Laparoscopic', 'Cholelithiasis', 'Diagnostic Errors', 'Female', 'Gallbladder', 'Humans', 'Middle Aged'] | 7,771,402 | [['E04.210.120.172.140', 'E04.502.250.520.160'], ['C06.130.409'], ['E01.354', 'N02.421.450.280'], ['A03.159.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Simulating irrational human behavior to prevent resource depletion. | In a situation with a limited common resource, cooperation between individuals sharing the resource is essential. However, people often act upon self-interest in irrational ways that threaten the long-term survival of the whole group. A lack of sustainable or environmentally responsible behavior is often observed. In t... | ['Cluster Analysis', 'Health Resources', 'Humans', 'Interpersonal Relations', 'Models, Theoretical', 'Social Environment'] | 25,760,635 | [['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['N03.349.340', 'N05.300.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['E05.599'], ['I01.880.853.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
A multifaceted coating on titanium dictates osteoimmunomodulation and osteo/angio-genesis towards ameliorative osseointegration. | A multifaceted coating for hard tissue implants, with favorable osteogenesis, angiogenesis, and osteoimmunomodulation abilities, would be of great value since it could improve osseointegration and alleviate prosthesis loosening. However, to date there are few coatings that fully satisfy these criteria. Herein we descri... | ['Animals', 'Cell Line', 'Cells, Cultured', 'Coated Materials, Biocompatible', 'Durapatite', 'Endothelial Cells', 'Humans', 'Macrophages', 'Mice', 'Neovascularization, Physiologic', 'Osseointegration', 'Osteoblasts', 'RAW 264.7 Cells', 'Surface Properties', 'Titanium'] | 29,454,274 | [['B01.050'], ['A11.251.210'], ['A11.251'], ['D25.130.420', 'J01.637.051.130.420'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['A11.436.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.372', 'A11.627.482', 'A11.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Generation, absorption, and transfer of mechanical energy during walking in children. | The purpose of this study was to characterize the manner in which net joint moments and non-muscular forces generate, absorb, and transfer mechanical energy during walking in able-bodied children. Standard gait data from seven healthy subjects between 6 and 17 years of age were combined with a dynamic model of the whol... | ['Absorption', 'Adolescent', 'Biomechanical Phenomena', 'Child', 'Female', 'Gait', 'Humans', 'Joints', 'Male', 'Mechanical Phenomena', 'Models, Biological', 'Walking'] | 22,885,224 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['M01.060.057'], ['G01.154.090', 'G01.374.089'], ['M01.060.406'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583'], ['G01.374'], ['E05.599.395'], ['G11.427.410.568.900', 'G11.427.410.698... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Helping people with psychosis to expand their social networks: the stakeholders' views. | BACKGROUND: People with psychosis experience more social isolation than any other diagnostic group and have smaller social networks than the general population. This isolation can have a detrimental effect on quality of life. No direct, standardised interventions have been developed to specifically target this issue. S... | ['Adult', 'Aged', 'Caregivers', 'Female', 'Focus Groups', 'Humans', 'Male', 'Middle Aged', 'Psychotic Disorders', 'Quality of Life', 'Social Isolation', 'Social Networking', 'Stakeholder Participation'] | 31,996,175 | [['M01.060.116'], ['M01.060.116.100'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.700.675'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['F01.145.813.781', '... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Relationship between phosphorylation and cytochrome P450 destruction. | In our previous report we showed cytochrome b5 to be a competitive inhibitor of cAMP-dependent protein kinase (PKA) for interaction with cytochrome P450 (P450). While P450 was phosphorylated, cytochrome b5 was not. The phosphorylation of P450 resulted in an inhibition of its catalytic activity. In this report we attemp... | ['Animals', 'Circular Dichroism', 'Cytochrome P-450 Enzyme System', 'Cytochromes b5', 'Kinetics', 'Liver', 'Phenobarbital', 'Phosphorylation', 'Protein Conformation', 'Protein Denaturation', 'Protein Kinases', 'Pseudomonas', 'Rats'] | 2,275,544 | [['B01.050'], ['E05.196.867.151'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D08.244.187.500', 'D12.776.422.220.187.500'], ['G01.374.661', 'G02.111.490'], ['A03.620'], ['D03.383.742.698.253.650'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['G02.111.570.820.709'], ['G01.154.651.750.500', 'G02... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A thiazolo[4,5-b]pyridine-based ?uorescent probe for detection of zinc ions and application for in vitro and in vivo bioimaging. | 2-HPTP, a novel thiazolo [4, 5-b] pyridine-based Zn2+ selective fluorescent probe has been synthesized and investigated. This probe exhibited a high selectivity towards Zn2+ over other biologically essential cations such as Na+, K+, Ca2+, or Mg2+. 2-HPTP formed a 1:1 complex with Zn2+ and showed a fluorescent enhanceme... | ['Animals', 'Biosensing Techniques', 'Caenorhabditis elegans', 'Cell Proliferation', 'Fluorescent Dyes', 'Humans', 'Ions', 'Molecular Structure', 'Optical Imaging', 'Pyridines', 'Triazoles', 'Tumor Cells, Cultured', 'Zinc'] | 29,759,218 | [['B01.050'], ['E05.601.043'], ['B01.050.500.500.294.400.875.660.250.250'], ['G04.161.750', 'G07.345.249.410.750'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497'], ['G02.111.570', 'G02.466'], ['E01.370.350.589', 'E05.642'], ['D03.383.725'], ['D03.383.129... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development. | Genetic analyses of dwarfing phenotypes resulting from targeted mutagenesis of the genes encoding the insulin-like growth factors (IGF-I and IGF-II) and their cognate type 1 IGF receptor (IGF1R) have demonstrated that this signaling system is a major determinant of mouse embryonic growth. Of the two IGF ligands, IGF-I ... | ['Animals', 'Crosses, Genetic', 'Embryonic and Fetal Development', 'Female', 'Fetal Growth Retardation', 'Humans', 'Insulin-Like Growth Factor II', 'Mice', 'Mutation', 'Phenotype', 'Pregnancy', 'Receptor, IGF Type 1', 'Receptor, Insulin'] | 9,281,335 | [['B01.050'], ['E05.393.281'], ['G07.345.500.325', 'G08.686.784.170'], ['C13.703.277.370', 'C16.300.390', 'C23.550.393.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.937.420', 'D12.776.124.862.425', 'D12.776.467.937.420', 'D23.529.937.420'], ['B01.050.150.900.649.313.992.635.505.500'], ['G05.365.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Upregulation of steroidogenic acute regulatory protein by hypoxia stimulates aldosterone synthesis in pulmonary artery endothelial cells to promote pulmonary vascular fibrosis. | BACKGROUND: The molecular mechanism(s) regulating hypoxia-induced vascular fibrosis are unresolved. Hyperaldosteronism correlates positively with vascular remodeling in pulmonary arterial hypertension, suggesting that aldosterone may contribute to the pulmonary vasculopathy of hypoxia. The hypoxia-sensitive transcripti... | ['Aldosterone', 'Animals', 'Cells, Cultured', 'Endothelial Cells', 'Humans', 'Hypoxia', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Phosphoproteins', 'Pulmonary Artery', 'Pulmonary Fibrosis', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', 'Up-Regulation'] | 25,001,622 | [['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['B01.050'], ['A11.251'], ['A11.436.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.079'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D12.776.744'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cloning and characterization of the rat glutathione peroxidase gene. | The increased activity of glutathione peroxidase (GSHPx) in rat lungs is associated with the development of tolerance of the animals to hyperoxia. To understand further the regulation of expression of this enzyme, the molecular structure of the corresponding rat gene was characterized. The rat GSHPx gene consists of tw... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cloning, Molecular', 'Exons', 'Female', 'Gene Expression Regulation, Enzymologic', 'Genes', 'Glutathione Peroxidase', 'Introns', 'Molecular Sequence Data', 'Nucleic Acid Hybridization', 'Promoter Regions, Genetic', 'Rats', 'Rats, Sprague-Dawley', 'Sequence Homology, ... | 1,451,786 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['G05.360.340.024.340.137.232'], ['G05.308.320'], ['G05.360.340.024.340'], ['D08.811.682.732.500'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['L01.453.245.667'], ['E05... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Lack of effect of captopril on glomerular hyperfiltration in normoalbuminuric normotensive insulin-dependent diabetic patients. | The aim of the present study was to evaluate the effects of captopril on the glomerular filtration rate (GFR) and urinary albumin excretion rate (UAER) of normoalbuminuric normotensive insulin-dependent diabetes mellitus (IDDM) patients with and without glomerular hyperfiltration. Eleven normoalbuminuric (UAER < 30 mic... | ['Adult', 'Albuminuria', 'Angiotensin-Converting Enzyme Inhibitors', 'Captopril', 'Diabetes Mellitus, Type 1', 'Female', 'Glomerular Filtration Rate', 'Humans', 'Kidney Glomerulus', 'Male'] | 9,405,980 | [['M01.060.116'], ['C12.777.934.734.269', 'C13.351.968.934.734.269', 'C23.888.942.750.269'], ['D27.505.519.389.745.085'], ['D12.125.072.401.623.270'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453.324.359', '... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
In vitro evaluation of nucleoside transport inhibition in vivo. | A method is described which permits rapid evaluation of the effects of nucleoside transport inhibitors on [3H]thymidine uptake into mouse whole blood cells. The uptake is measured after 15-20 sec by withdrawing 100 microliters of blood from the orbital sinus into microcapillary pipets that have been prelabeled with [3H... | ['Animals', 'Biological Transport', 'Dipyridamole', 'Dose-Response Relationship, Drug', 'Humans', 'In Vitro Techniques', 'Male', 'Methotrexate', 'Mice', 'Mice, Inbred AKR', 'Mice, Inbred Strains', 'Nucleosides', 'Thymidine', 'Time Factors'] | 3,702,469 | [['B01.050'], ['G03.143'], ['D03.383.742.175'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D03.633.100.733.631.192.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.318', 'B01.050.150.900.649.313.992.635.505.500.400.318'], ['B01.05... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Wild Birds in Romania Are More Exposed to West Nile Virus Than to Newcastle Disease Virus. | The aim of this study was to evaluate the seroprevalence of West Nile virus (WNV) and Newcastle disease virus (NDV) in wild and domestic birds from Romania. During 2011-2014, 159 plasma samples from wild birds assigned to 11 orders, 27 families, and 61 species and from 21 domestic birds (Gallus gallus domesticus, Anas ... | ['Animals', 'Antibodies, Viral', 'Bird Diseases', 'Birds', 'Chickens', 'Ducks', 'Geography', 'Newcastle Disease', 'Newcastle disease virus', 'Poultry Diseases', 'Romania', 'Seroepidemiologic Studies', 'West Nile Fever', 'West Nile virus'] | 26,824,796 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['C22.131'], ['B01.050.150.900.248'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['B01.050.150.900.248.050.200', 'B01.050.150.900.248.690.345'], ['H01.277.500'], ['C01.925.782.580.600.080.60... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
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