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Walking on the edge: meanings of living in an ageing body and using a walker in everyday life - a phenomenological hermeneutic study. | BACKGROUND: In order to maintain one's state of health whilst growing older, the ability to walk is essential.AIM AND OBJECTIVE: The aim of this study was to illuminate the meanings of the lived experience of living in an ageing body and using a walker in daily life.METHODS: Narrative interviews were performed with sev... | ['Activities of Daily Living', 'Adaptation, Psychological', 'Aged', 'Aging', 'Attitude to Health', 'Geriatric Nursing', 'Humans', 'Mobility Limitation', 'Nursing Methodology Research', 'Self Concept', 'Self Efficacy', 'Walkers', 'Walking'] | 22,676,835 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['F01.058'], ['M01.060.116.100'], ['G07.345.124'], ['F01.100.150', 'N05.300.150'], ['H02.478.676.236', 'N02.421.533.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.550'], ['H01.770.644.145.390.634', 'H02.478.395.634', 'N04.590.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Instability and site-specific excision of integration-proficient mycobacteriophage L5 plasmids: development of stably maintained integrative vectors. | Integrative vectors expressing foreign genes are used as tools for the development of recombinant vaccines in mycobacteria since it is assumed that these vectors are stably maintained even without antibiotic selection. We here demonstrate that integration-proficient vectors are lost from the mycobacterial genome in hig... | ['Attachment Sites, Microbiological', 'Genetic Vectors', 'Integrases', 'Mycobacteriophages', 'Mycobacterium bovis', 'Mycobacterium smegmatis', 'Plasmids', 'Polymerase Chain Reaction', 'Rec A Recombinases', 'Transformation, Bacterial', 'Virus Integration'] | 11,310,445 | [['G05.360.340.024.079'], ['G05.360.337'], ['D08.811.739.500'], ['B04.123.502'], ['B03.510.024.962.500.402', 'B03.510.460.400.410.552.552.402'], ['B03.510.024.962.500.720.662', 'B03.510.460.400.410.552.552.720.662'], ['G05.360.600'], ['E05.393.620.500'], ['D08.811.739.650', 'D08.811.913.696.445.692'], ['E05.393.350.810... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Detecting cognitive dysfunction in multiple sclerosis with a magnetic resonance imaging rating scale: a pilot study. | OBJECTIVE: In multiple sclerosis (MS), magnetic resonance imaging (MRI) predictors of cognitive impairment are based on sophisticated computer-generated analyses that are difficult to apply in clinical settings. This study investigated the clinical usefulness of a new visual rating scale, the Cholinergic Pathways Hyper... | ['Brain', 'Cholinergic Fibers', 'Cognition Disorders', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Multiple Sclerosis', 'Neuropsychological Tests', 'Pilot Projects', 'Severity of Illness Index', 'Visual Pathways'] | 15,858,457 | [['A08.186.211'], ['A08.675.127.500', 'A08.675.542.234', 'A11.671.188.500', 'A11.671.501.234'], ['F03.615.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['F04.711.513'], ['E05.318.372.750', 'E05.337.737... | ['Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Preclinical Pharmacokinetic Studies of the Tritium Labelled D-Enantiomeric Peptide D3 Developed for the Treatment of Alzheimer?s Disease. | Targeting toxic amyloid beta (Aâ) oligomers is currently a very attractive drug development strategy for treatment of Alzheimer?s disease. Using mirror-image phage display against Aâ1-42, we have previously identified the fully D-enantiomeric peptide D3, which is able to eliminate Aâ oligomers and has proven therapeuti... | ['Alzheimer Disease', 'Animals', 'Area Under Curve', 'Blood Proteins', 'Chromatography, Thin Layer', 'Disease Models, Animal', 'Drug Evaluation, Preclinical', 'Half-Life', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Microsomes, Liver', 'Oligopeptides', 'Protein Binding', 'ROC Curve', 'Stereoisomerism', '... | 26,046,986 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['B01.050'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D12.776.124'], ['E05.196.181.400.537'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.290.750', 'E05.337.550'], ['G01.910.405'], ['B01.050.150.900.649.313.9... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
PDGFR-â (+) perivascular cells from infantile hemangioma display the features of mesenchymal stem cells and show stronger adipogenic potential in vitro and in vivo. | Infantile hemangioma, a common benign tumor of infancy, grows quickly in the first year of life, and then regresses slowly to fibrofatty tissue in childhood. The accumulation of fibrofatty tissue in hemangioma involution indicates adipogenesis during this period. Perivascular cells (PCs) from multiple organs display mu... | ['Adipogenesis', 'Animals', 'Cell Differentiation', 'Cell Lineage', 'Cell Separation', 'Flow Cytometry', 'Fluorescent Antibody Technique', 'Hemangioma', 'Humans', 'In Vitro Techniques', 'Mesenchymal Stem Cells', 'Mice', 'Mice, Nude', 'Multipotent Stem Cells', 'Pericytes', 'Receptor, Platelet-Derived Growth Factor beta'... | 25,031,705 | [['G04.152.149'], ['B01.050'], ['G04.152'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E0... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neutrophil elastase contributes to the development of ischemia-reperfusion-induced liver injury by decreasing endothelial production of prostacyclin in rats. | We previously reported that nitric oxide (NO) derived from endothelial NO synthase (NOS) increased endothelial prostacyclin (PGI(2)) production in rats subjected to hepatic ischemia-reperfusion (I/R). The present study was undertaken to determine whether neutrophil elastase (NE) decreases endothelial production of PGI(... | ['6-Ketoprostaglandin F1 alpha', 'Animals', 'Capillary Permeability', 'Cephalosporins', 'Chemokines, CXC', 'Cyclooxygenase Inhibitors', 'Endothelium', 'Enzyme Inhibitors', 'Epoprostenol', 'Glycine', 'Iloprost', 'Indomethacin', 'Intercellular Signaling Peptides and Proteins', 'Leukocyte Elastase', 'Liver', 'Liver Circul... | 15,246,960 | [['D10.251.355.255.550.400.350', 'D10.251.355.325.450', 'D23.469.050.175.725.400.350'], ['B01.050'], ['G03.143.330', 'G09.330.165'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['D12.644.276.374.200.120', 'D12.776.467.374.200.120', 'D23.125.300.120', 'D23.469.200.120', 'D23.529.374.200.120'], ['D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The combi-targeting concept: in vitro and in vivo fragmentation of a stable combi-nitrosourea engineered to interact with the epidermal growth factor receptor while remaining DNA reactive. | PURPOSE: JDA58 (NSC 741282), a "combi-molecule" optimized in the context of the "combi-targeting concept," is a nitrosourea moiety tethered to an anilinoquinazoline. Here, we sought to show its binary epidermal growth factor receptor (EGFR)/DNA targeting property and to study its fragmentation in vitro and in vivo.EXPE... | ['Animals', 'Cell Line, Tumor', 'Comet Assay', 'DNA', 'DNA Damage', 'Drug Screening Assays, Antitumor', 'ErbB Receptors', 'Humans', 'Inhibitory Concentration 50', 'Male', 'Mass Spectrometry', 'Mice', 'Microscopy, Fluorescence', 'Neoplasm Transplantation', 'Nitrosourea Compounds', 'Phosphorylation'] | 17,200,372 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.560.150'], ['D13.444.308'], ['G05.200'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Provider management strategies of abnormal test result alerts: a cognitive task analysis. | OBJECTIVE: Electronic medical records (EMRs) facilitate abnormal test result communication through "alert" notifications. The aim was to evaluate how primary care providers (PCPs) manage alerts related to critical diagnostic test results on their EMR screens, and compare alert-management strategies of providers with hi... | ['Computer User Training', 'Continuity of Patient Care', 'Diagnostic Imaging', 'Electronic Health Records', 'Female', 'Humans', 'Male', "Practice Patterns, Physicians'", 'Primary Health Care', 'Reminder Systems', 'Task Performance and Analysis', 'Texas', 'Veterans'] | 20,064,805 | [['I02.903.080'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['E01.370.350'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.374.577', 'N05.300.625'], ['N04.590.2... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
[The prevalence of beta-thalassemia heterozygotes compound alpha-thalassemia in Guangdong district]. | OBJECTIVE: To investigate the prevalence of beta-thalassemia (beta-thal) heterozygotes compound alpha-thal in Guangdong area.METHODS: alpha-thal 1 genes were amplified in 500 beta-thal carriers diagnosed by reverse dot blotting (RDB) using gap-PCR method, alpha-thal 2 genes were detected in 400 of the 500 beta-thal car... | ['Adult', 'Blotting, Southern', 'China', 'DNA', 'Female', 'Gene Frequency', 'Genotype', 'Globins', 'Heterozygote', 'Humans', 'Male', 'Prevalence', 'alpha-Thalassemia', 'beta-Thalassemia'] | 11,769,674 | [['M01.060.116'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['Z01.252.474.164'], ['D13.444.308'], ['G05.330'], ['G05.380'], ['D12.776.422.316'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Transesophageal echocardiography in the diagnosis of left atrial appendage aneurysm. | Intrapericardial left atrial appendage aneurysm is rare. We describe the transthoracic and transesophageal echocardiographic findings in a 42-year-old man with atrial arrhythmia and an abnormal left atrial appendage on chest roentgenogram. Presence of an intrapericardial left atrial appendage aneurysm was confirmed at ... | ['Adult', 'Echocardiography', 'Heart Aneurysm', 'Heart Atria', 'Humans', 'Male', 'Radiography'] | 2,245,034 | [['M01.060.116'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C14.280.358', 'C14.907.055.608'], ['A07.541.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evolution of Insect Iridescence: Origins of Three-Dimensional Photonic Crystals in Weevils (Coleoptera: Curculionoidea). | A variety of photonic mechanisms give rise to iridescence and other structural colors in insects. In weevils (Coleoptera: Curculionoidea), iridescence is created by the most complex of these mechanisms, the three-dimensional photonic crystal. These self-assembling crystals take the form of triply periodic networks with... | ['Animals', 'Biological Evolution', 'Iridescence', 'Sensilla', 'Weevils'] | 31,093,648 | [['B01.050'], ['G05.045', 'G16.075'], ['G01.590.310'], ['A13.093.500'], ['B01.050.500.131.617.720.500.500.375.900']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
"Bunt bradycardia": two cases of slowing of heart rate inflight during negative Gz. | Two cases are presented of Canadian Forces pilots who experienced inflight bradycardia during 15 s of -1 Gz acceleration. The bradycardia was characterized by rapid cardio-deceleration, stable bradycardia, then cardio-acceleration during recovery following the -Gz exposure that was slower than the cardio-deceleration. ... | ['Aerospace Medicine', 'Gravitation', 'Heart Rate', 'Humans'] | 8,002,914 | [['H02.403.029'], ['G01.060.350'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Sex hormones in amenorrheic women with alcoholic liver disease. | Urinary excretion of estrogens and plasma concentrations of estrone, estradiol, LH, FSH, PRL, progesterone, testosterone, and sex hormone binding globulin were measured in nine chronic alcoholic women with cirrhosis or alcoholic fatty liver. They were aged 24-40 yr and all had secondary amenorrhea which had lasted for ... | ['Adult', 'Amenorrhea', 'Estrogens', 'Fatty Liver, Alcoholic', 'Female', 'Follicle Stimulating Hormone', 'Gonadal Steroid Hormones', 'Gonadotropin-Releasing Hormone', 'Humans', 'Liver Cirrhosis, Alcoholic', 'Liver Diseases, Alcoholic', 'Luteinizing Hormone', 'Progesterone', 'Prolactin', 'Sex Hormone-Binding Globulin', ... | 6,427,268 | [['M01.060.116'], ['C23.550.568.500'], ['D27.505.696.399.472.277'], ['C06.552.241.390', 'C06.552.645.390', 'C25.775.100.087.645.390'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['D06.472.334.851'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460',... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
INCREASED RATES OF SMOKING CESSATION OBSERVED AMONG TRANSGENDER WOMEN RECEIVING HORMONE TREATMENT. | OBJECTIVE: According to the Centers for Disease Control, while 68% of adult smokers nationally desire to quit, only 6.2% successfully quit in a given year. Transgender women seen for hormone therapy at Boston Medical Center (BMC) are strongly advised to quit smoking before the start of treatment, not only due to genera... | ['Adult', 'Aged', 'Case-Control Studies', 'Estradiol', 'Estrogen Replacement Therapy', 'Estrogens', 'Estrogens, Conjugated (USP)', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mineralocorticoid Receptor Antagonists', 'Motivation', 'Retrospective Studies', 'Smoking', 'Smoking Cessation', 'Spironolactone', 'Transgender Pe... | 27,682,351 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['E02.319.452.150'], ['D27.505.696.399.472.277'], ['D06.472.334.851.437.988'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tobacco and alcohol use among firefighters during their first 3 years of service. | Firefighters constitute an understudied occupational group that are exposed to a great deal of occupational stress including potentially traumatic stress. As such, higher prevalence rates of posttraumatic stress disorder (PTSD) and substance use disorders have been observed within this population; however, very little ... | ['Adult', 'Alcohol Drinking', 'Depression', 'Female', 'Firefighters', 'Humans', 'Male', 'Mental Health', 'Prevalence', 'Stress Disorders, Post-Traumatic', 'Tobacco Use', 'Young Adult'] | 29,771,556 | [['M01.060.116'], ['F01.145.317.269'], ['F01.145.126.350'], ['M01.526.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.418', 'N01.400.500'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['F03.950.750.500'], ['F01.145.958'], ['M01.060.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Regular physical activity eliminates the harmful association of television watching with multimorbidity. A cross-sectional study from the European Social Survey. | The aims of the study were to analyse the association of television viewing, physical activity (PA), and multimorbidity; and to understand if PA attenuates or eliminates the detrimental associations between television viewing and multimorbidity. This is a cross-sectional study based on data from the European Social Sur... | ['Body Mass Index', 'Cross-Sectional Studies', 'Europe', 'Exercise', 'Female', 'Humans', 'Life Style', 'Male', 'Middle Aged', 'Multimorbidity', 'Noncommunicable Diseases', 'Obesity', 'Risk Factors', 'Surveys and Questionnaires', 'Television', 'Time Factors'] | 29,360,480 | [['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458'], ['M01.060.116.630'], ['N05.715.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Technology, Industry, and... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Knowledge, attitude and practice for cervical cancer prevention and control among women of childbearing age in Hossana Town, Hadiya zone, Southern Ethiopia: Community-based cross-sectional study. | BACKGROUND: Cervical cancer is the second most common female cancer which Ethiopia put a strategic goal to reduce its incidence and mortality by 2020. Lack of knowledge and poor attitude towards the disease and risk factors can affect screening practice and development of preventive behavior for cervical cancer. The ai... | ['Adolescent', 'Adult', 'Cervix Uteri', 'Cross-Sectional Studies', 'Ethiopia', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Middle Aged', 'Papanicolaou Test', 'Socioeconomic Factors', 'Uterine Cervical Neoplasms', 'Young Adult'] | 28,742,851 | [['M01.060.057'], ['M01.060.116'], ['A05.360.319.679.256'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.058.290.120.310'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.225.500.384.100.422', 'E01.370.225.9... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The cost-effectiveness of single-dose azithromycin for treatment of incubating syphilis. | BACKGROUND: Treatment of incubating syphilis with intramuscular benzathine penicillin in exposed sex partners is not always practical in the field, and exposed partners may not adhere to referrals for treatment at clinical facilities. The availability of a single-dose oral therapy could increase the number of partners ... | ['Administration, Oral', 'Anti-Bacterial Agents', 'Azithromycin', 'Cost-Benefit Analysis', 'Decision Support Techniques', 'Drug Administration Schedule', 'Humans', 'Injections, Intramuscular', 'Penicillin G Benzathine', 'Referral and Consultation', 'Sexual Partners', 'Syphilis, Latent', 'United States'] | 12,782,951 | [['E02.319.267.100'], ['D27.505.954.122.085'], ['D02.540.576.500.992.050'], ['N03.219.151.125'], ['E05.245', 'L01.313.500.750.190'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.460'], ['D02.065.589.099.750.750.685', 'D02.886.108.750.750.685', 'D03.633.100.300.750.750.685'], ['N04... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
[Social scenarios in Latin America and the Caribbean]. | A wide range of sources have pointed out the magnitude and depth of the social problems that trouble Latin America and the Caribbean and the risks that these problems pose for democracy. Although there are other issues that merit consideration, this article briefly outlines nine key social problems: 1) the increase in ... | ['Caribbean Region', 'Latin America', 'Social Problems'] | 11,026,780 | [['Z01.107.084'], ['Z01.107.424'], ['I01.880.735']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
[Boredom in zoo animals--an relevant animal welfare problem?]. | Modern sciences, the philosophy of insight, and psychology are the basis for a discussion of the question, whether animals can experience boredom or even suffer from it. Various examples are used for illustration. The results show that neither a direct statement is possible nor can a logical conclusion by indirect anal... | ['Animal Welfare', 'Animals', 'Animals, Zoo', 'Boredom', 'Cats', 'Child', 'Humans', 'Motivation', 'Stereotyped Behavior'] | 8,578,562 | [['I01.880.604.100'], ['B01.050'], ['B01.050.050.448'], ['F01.470.192'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['F01.145.896']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Global quantitative analysis of phosphorylation underlying phencyclidine signaling and sensorimotor gating in the prefrontal cortex. | Prepulse inhibition (PPI) is an example of sensorimotor gating and deficits in PPI have been demonstrated in schizophrenia patients. Phencyclidine (PCP) suppression of PPI in animals has been studied to elucidate the pathological elements of schizophrenia. However, the molecular mechanisms underlying PCP treatment or P... | ['Acoustic Stimulation', 'Animals', 'Disease Models, Animal', 'Long-Term Potentiation', 'Male', 'Phencyclidine', 'Phosphorylation', 'Prefrontal Cortex', 'Prepulse Inhibition', 'Rats', 'Rats, Sprague-Dawley', 'Reflex, Startle', 'Schizophrenia', 'Sensory Gating', 'Signal Transduction'] | 25,869,802 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G11.561.638.350'], ['D03.383.621.699'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['A08.186.211.200.885.287.500.270.700'], ['G11.561.794.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.64... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Dermatofibrosarcoma protuberans. A clinico-pathologic analysis of 5 cases]. | The author study the clinical histories and the histopathologic findings in five patients who were hospitalized in the National Oncological Institute, between 1983 and 1993 in whom the diagnosis of Dermatofibrosarcoma protuberans was established. He note the age, sex, localization of the tumor, the frequency and cause ... | ['Adolescent', 'Adult', 'Dermatofibrosarcoma', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Middle Aged', 'Skin Neoplasms'] | 7,938,714 | [['M01.060.057'], ['M01.060.116'], ['C04.557.450.565.590.350.320', 'C04.557.450.795.350.320'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.805', 'C17.800.882']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibition of NF-kappa B and oxidative pathways in human dendritic cells by antioxidative vitamins generates regulatory T cells. | Dendritic cells (DCs) are central to T cell immunity, and many strategies have been used to manipulate DCs to modify immune responses. We investigated the effects of antioxidants ascorbate (vitamin C) and alpha-tocopherol (vitamin E) on DC phenotype and function. Vitamins C and E are both antioxidants, and concurrent u... | ['Antioxidants', 'Apoptosis', 'Ascorbic Acid', 'Cell Differentiation', 'Cells, Cultured', 'Clonal Anergy', 'Dendritic Cells', 'Dexamethasone', 'Down-Regulation', 'Drug Combinations', 'Humans', 'Immunophenotyping', 'Intracellular Fluid', 'NF-kappa B', 'Oxidation-Reduction', 'Protein Kinase C', 'Reactive Oxygen Species',... | 15,944,264 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.146.954.035'], ['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['G04.152'], ['A11.251'], ['G12.535.425.100'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
When the waves of European Neolithization met: first paleogenetic evidence from early farmers in the southern Paris Basin. | An intense debate concerning the nature and mode of Neolithic transition in Europe has long received much attention. Recent publications of paleogenetic analyses focusing on ancient European farmers from Central Europe or the Iberian Peninsula have greatly contributed to this debate, providing arguments in favor of maj... | ['Archaeology', 'DNA, Mitochondrial', 'Europe', 'European Continental Ancestry Group', 'Farmers', 'France', 'Haplotypes', 'Humans', 'Molecular Sequence Data', 'Paris'] | 25,928,633 | [['I01.076.201.208'], ['D13.444.308.283.225'], ['Z01.542'], ['M01.686.508.400'], ['M01.526.390'], ['Z01.542.286'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['Z01.433.800', 'Z01.542.286.588']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 |
Admission variables predictive of academic struggle in a PharmD program. | Objective. To characterize and describe admission variables predictive of poor grade attainment by students in 2 pathways to a doctor of pharmacy (PharmD) program.Methods. A retrospective analysis of course grades of PharmD students admitted from 2000 to 2009 (N= 1,019) in the traditional degree pathway ("1 plus 5" deg... | ['Chi-Square Distribution', 'College Admission Test', 'Curriculum', 'Education, Pharmacy', 'Educational Status', 'Humans', 'Missouri', 'Retrospective Studies', 'School Admission Criteria', 'Schools, Pharmacy', 'Students, Pharmacy', 'Universities'] | 23,459,593 | [['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['I02.399.272'], ['I02.158'], ['I02.358.525'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.510.515'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Comparing mortality and time until death for medicare HMO and FFS beneficiaries. | OBJECTIVE: To compare adjusted mortality rates of TEFRA-risk HMO enrollees and disenrollees with rates of beneficiaries enrolled in the Medicare fee-for-service sector (FFS), and to compare the time until death for decedents in these three groups.DATA SOURCE: Data are from the 124 counties with the largest TEFRA-risk H... | ['Aged', 'Aged, 80 and over', 'Disabled Persons', 'Fee-for-Service Plans', 'Female', 'Health Maintenance Organizations', 'Hospitalization', 'Humans', 'Logistic Models', 'Male', 'Medicare', 'Mortality', 'Quality of Health Care', 'Retrospective Studies', 'Time Factors', 'Treatment Outcome', 'United States'] | 11,221,818 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.150'], ['N03.219.442.195', 'N03.219.521.710.305.090', 'N04.452.758.745.225'], ['N03.219.521.576.343.800.400', 'N03.219.521.576.343.925.400', 'N04.452.758.244.425', 'N04.590.374.410.400'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The differential impact of PDE4 subtypes in human lung fibroblasts on cytokine-induced proliferation and myofibroblast conversion. | Lung fibroblast proliferation and differentiation into myofibroblasts are pathological key events during development of lung fibrosis. Cyclic nucleotide signaling is described as a negative modulator of these cellular processes, and cyclic nucleotide degrading type 4 phosphodiesterases (PDE4) are important regulators o... | ['Aminopyridines', 'Benzamides', 'Cell Differentiation', 'Cell Proliferation', 'Cells, Cultured', 'Cyclic Nucleotide Phosphodiesterases, Type 4', 'Cyclopropanes', 'Cytokines', 'Fibroblast Growth Factor 2', 'Fibroblasts', 'Gene Expression Profiling', 'Humans', 'Interleukin-1beta', 'Isoenzymes', 'Lung', 'Myofibroblasts',... | 21,520,048 | [['D02.092.080', 'D03.383.725.050'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D08.811.277.352.640.150.400', 'D12.644.360.008.400', 'D12.776.476.008.400'], ['D02.455.426.392.368.533'], ['D12.644.276.374', 'D12.776.467.374',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Circadian Misalignment Increases C-Reactive Protein and Blood Pressure in Chronic Shift Workers. | Shift work is a risk factor for inflammation, hypertension, and cardiovascular disease. This increased risk cannot be fully explained by classical risk factors. Shift workers' behavioral and environmental cycles are typically misaligned relative to their endogenous circadian system. However, there is little information... | ['Adult', 'Biomarkers', 'Blood Pressure', 'C-Reactive Protein', 'Cardiovascular Diseases', 'Chronobiology Disorders', 'Circadian Rhythm', 'Female', 'Humans', 'Hypertension', 'Inflammation', 'Male', 'Middle Aged', 'Risk Factors', 'Shift Work Schedule', 'Sleep', 'Work Schedule Tolerance', 'Young Adult'] | 28,347,188 | [['M01.060.116'], ['D23.101'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['C14'], ['C10.281'], ['G07.180.562.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C23.550.470'], ['M01.060.116.630'], ['E05.318.740.600.800.725', 'N0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Histologic Evaluation of Critical Size Defect Healing With Natural and Synthetic Bone Grafts in the Pigeon ( Columba livia ) Ulna. | Fracture and bone segment loss are major clinical problems in birds. Achieving bone formation and clinical union in a fracture case is important for the survival of the bird. To evaluate the efficacy of bone grafts for defect healing in birds, 2 different bone grafts were investigated in the healing of a bone defect in... | ['Animals', 'Biomechanical Phenomena', 'Bone Matrix', 'Bone Substitutes', 'Bone Transplantation', 'Columbidae', 'Durapatite', 'Fracture Fixation', 'Fractures, Bone', 'Wings, Animal'] | 26,115,209 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['A10.165.265.166'], ['D25.130.325', 'J01.637.051.130.325'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['B01.050.150.900.248.165.150'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.02... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Polymorphisms of the BDNF gene show neither association with multiple sclerosis susceptibility nor clinical course. | Brain-derived neurotrophic factor (BDNF) has been proposed a protective role in multiple sclerosis (MS) in several studies. The val(66)met polymorphism alters the function of the BDNF protein, and has along with rs56164415 previously been reported to be associated with MS. We genotyped BDNF SNPs val(66)met and rs561644... | ['Adult', 'Age of Onset', 'Brain-Derived Neurotrophic Factor', 'Disease Progression', 'Female', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Humans', 'Male', 'Methionine', 'Multiple Sclerosis', 'Norway', 'Polymorphism, Genetic', 'Valine'] | 22,341,604 | [['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['C23.550.291.656'], ['E05.393.385'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.030.676', 'D12.125.142.557'... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Direct detection of potassium cations bound to G-quadruplex structures by solid-state 39K NMR at 19.6 T. | We report solid-state 39K NMR detection of the K+ ions bound to three G-quadruplex structures formed by self-assembly of 5'-tert-butyl-dimethylsilyl-2',3'-O-isopropylidene guanosine, guanosine, and guanosine 5'-monophosphate. The 39K NMR spectra clearly show different spectral signatures for K+ ions inside the G-quadru... | ['Cations, Monovalent', 'DNA', 'G-Quadruplexes', 'Guanosine', 'Nuclear Magnetic Resonance, Biomolecular', 'Nucleic Acid Conformation', 'Potassium'] | 12,797,784 | [['D01.248.497.300.459'], ['D13.444.308'], ['G02.111.570.820.486.550', 'G05.360.580.550'], ['D03.633.100.759.590.454', 'D13.570.583.454', 'D13.570.800.453'], ['E05.196.867.519.550'], ['G02.111.570.820.486', 'G05.360.580'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
"One plate/three-reporter" assay format for the detection and validation of yeast two-hybrid interactions. | We describe a novel assay format for the Gal4-based yeast two-hybrid-system, in which the readout from three different reporter genes is measured sequentially in a single microplate. Activation of the URA3, MEL1, and lacZ reporters in response to a protein-protein interaction is monitored by measuring sequentially: (i)... | ['Fungal Proteins', 'Genes, Reporter', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Two-Hybrid System Techniques', 'Yeasts'] | 15,560,140 | [['D12.776.354'], ['G05.360.340.024.340.435'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872'], ['E05.393.220.870', 'E05.601.690.650', 'E05.601.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor. | The structure of the type II DHQase from Streptomyces coelicolor has been solved and refined to high resolution in complexes with a number of ligands, including dehydroshikimate and a rationally designed transition state analogue, 2,3-anhydro-quinic acid. These structures define the active site of the enzyme and the ro... | ['Amino Acid Sequence', 'Animals', 'Bacterial Proteins', 'Binding Sites', 'Crystallography, X-Ray', 'Hydro-Lyases', 'Models, Molecular', 'Molecular Sequence Data', 'Molecular Structure', 'Protein Folding', 'Protein Structure, Quaternary', 'Protein Structure, Tertiary', 'Sequence Alignment', 'Shikimic Acid', 'Streptomyc... | 11,937,054 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.097'], ['G02.111.570.120'], ['E05.196.309.742.225'], ['D08.811.520.241.300'], ['E05.599.595'], ['L01.453.245.667'], ['G02.111.570', 'G02.466'], ['G01.154.651', 'G02.111.688'], ['G02.111.570.820.709.550'], ['G02.111.570.820.709.610'], ['E05.393.751'], [... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Rapid evolutionary dynamics in a 2.8-Mb chromosomal region containing multiple prolamin and resistance gene families in Aegilops tauschii. | Prolamin and resistance gene families are important in wheat food use and in defense against pathogen attacks, respectively. To better understand the evolution of these multi-gene families, the DNA sequence of a 2.8-Mb genomic region, representing an 8.8 cM genetic interval and harboring multiple prolamin and resistanc... | ['Chromosomes, Plant', 'Evolution, Molecular', 'Gene Duplication', 'Genes, Plant', 'Genome, Plant', 'Phylogeny', 'Prolamins', 'Triticum'] | 27,228,577 | [['A11.284.187.560', 'A18.005', 'G05.360.162.560'], ['G05.045.250', 'G16.075.250'], ['G05.365.590.320', 'G05.558.320'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.360.340.365'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D12.776.765.433.500', 'D12.776.765.725.500'], ['B01.650.940.800.575.912.250.822.91... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The G2028R glycine substitution mutation in COL7A1 leads to marked inter-familiar clinical heterogeneity in dominant dystrophic epidermolysis bullosa. | BACKGROUND: Glycine substitution mutations in COL7A1 not only cause dominant dystrophic epidermolysis bullosa (DDEB), but can also be silent mutations which lead to recessive dystrophic epidermolysis bullosa (RDEB) in combination with additional mutations in the other allele.OBJECTIVE: In this study, we have examined a... | ['Adult', 'Amino Acid Substitution', 'Collagen Type VII', 'Epidermolysis Bullosa Dystrophica', 'Family Health', 'Female', 'Genetic Heterogeneity', 'Glycine', 'Humans', 'Male', 'Pedigree', 'Phenotype'] | 15,113,589 | [['M01.060.116'], ['E05.393.420.601.035', 'G05.558.109'], ['D12.776.860.300.250.400.300'], ['C16.131.831.493.160', 'C16.320.850.275.160', 'C17.300.200.367', 'C17.800.804.493.160', 'C17.800.827.275.160', 'C17.800.865.410.160'], ['N01.400.300'], ['G05.365.331'], ['D12.125.481'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Large-Scale Membrane- and Lignin-Modified Adsorbent-Assisted Extraction and Preconcentration of Triazine Analogs and Aflatoxins. | The large-scale simultaneous extraction and concentration of aqueous solutions of triazine analogs, and aflatoxins, through a hydrocarbon-based membrane (e.g., polyethylene, polyethylene/polypropylene copolymer) under ambient temperature and atmospheric pressure is reported. The subsequent adsorption of analyte in the ... | ['Adsorption', 'Aflatoxins', 'Chemistry Techniques, Analytical', 'Chromatography, High Pressure Liquid', 'Hydrocarbons', 'Lignin', 'Membranes, Artificial', 'Polyethylene', 'Polypropylenes', 'Silica Gel', 'Solubility', 'Solvents', 'Spectroscopy, Fourier Transform Infrared', 'Triazines', 'Viscosity'] | 28,398,252 | [['G01.030', 'G02.020'], ['D03.383.663.283.119', 'D03.633.100.150.119', 'D23.946.587.142'], ['E05.196'], ['E05.196.181.400.300'], ['D02.455'], ['D05.750.078.562.180.515', 'D05.750.078.687', 'D20.538', 'D25.720.099.687', 'J01.637.051.720.099.687'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['D02.455.326.271.665... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Health-related quality-of-life treatments for severe haemophilia: utility measurements using the Standard Gamble technique. | Prophylaxis for haemophilia improves outcomes, but at a substantial cost. Cost-utility analysis balances improvements seen in health-related quality of life (HRQoL) against costs, with the purpose of aiding healthcare decision-making. This analysis uses a measure of HRQoL known as utility. The objective of this study w... | ['Adult', 'Attitude to Health', 'Catheters, Indwelling', 'Cost-Benefit Analysis', 'Decision Support Techniques', 'Drug Administration Schedule', 'Factor IX', 'Factor VIII', 'Female', 'Health Services Needs and Demand', 'Hemophilia A', 'Hemophilia B', 'Humans', 'Male', 'Middle Aged', 'Parents', 'Quality of Life', 'Sickn... | 11,952,846 | [['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['E07.132.500'], ['N03.219.151.125'], ['E05.245', 'L01.313.500.750.190'], ['E02.319.283'], ['D08.622.355', 'D12.776.124.125.375', 'D12.776.811.243.355', 'D23.119.375'], ['D12.776.124.125.350', 'D12.776.811.286', 'D23.119.350'], ['N03.349.380.420', 'N05.300.450'], ['C15.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Preparation of a naturally occurring D-erythro-(2S, 3R)-sphingosylphosphocholine using Shewanella alga NS-589. | Sphingosylphosphocholine, an N-deacylated derivative of sphingomyelin, has been found to be involved in many cellular events. This paper describes a new method for preparation of a D-erythro-sphingosylphosphocholine, which is naturally occurring but difficult to prepare by chemical methods, using marine bacteria as a b... | ['Amidohydrolases', 'Chromatography, Thin Layer', 'Gram-Negative Facultatively Anaerobic Rods', 'Magnetic Resonance Spectroscopy', 'Phosphorylcholine', 'Spectrometry, Mass, Fast Atom Bombardment', 'Sphingosine', 'Stereoisomerism'] | 9,323,602 | [['D08.811.277.087'], ['E05.196.181.400.537'], ['B03.440.450'], ['E05.196.867.519'], ['D02.092.877.883.333.700', 'D02.675.276.232.700'], ['E05.196.566.750'], ['D02.033.100.700', 'D02.033.455.843', 'D02.092.063.700'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Guaianolide sesquiterpenoids from Ainsliaea yunnanensis. | Six previously undescribed C17-guaianolides, a previously undescribed guaianolide alkaloid, and two previously undescribed guaianolides as well as 10 known guaianolides were obtained from an ethanol extract of Ainsliaea yunnanensis Franch. The chemical structures of all previously reported sesquiterpenoids were determi... | ['Alkaloids', 'Animals', 'Asteraceae', 'Cell Survival', 'Inhibitory Concentration 50', 'Lipopolysaccharides', 'Macrophages', 'Mice', 'Molecular Structure', 'Nitric Oxide', 'Nuclear Magnetic Resonance, Biomolecular', 'Sesquiterpenes, Guaiane'] | 28,411,482 | [['D03.132'], ['B01.050'], ['B01.650.940.800.575.912.250.100'], ['G04.346'], ['E05.940.350', 'G07.690.936.563'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['B01.050.150.900.649.313.992... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Focused antithrombotic therapy: novel anti-platelet salicylates with reduced ulcerogenic potential and higher first-pass detoxification than aspirin in rats. | The use of aspirin as an anti-platelet drug is limited by its propensity to induce gastric injury and by its adverse effect on vascular prostacyclin formation. Two phenolic non-steroidal anti-inflammatory drugs (salicylic acid and diflunisal) were modified by esterification with a series of O-acyl moieties. The short-t... | ['Animals', 'Anti-Inflammatory Agents', 'Arthritis, Experimental', 'Aspirin', 'Blood Platelets', 'Diflunisal', 'Dose-Response Relationship, Drug', 'Female', 'Fibrinolytic Agents', 'Gastric Mucosa', 'In Vitro Techniques', 'Inactivation, Metabolic', 'Liver', 'Platelet Aggregation', 'Platelet Aggregation Inhibitors', 'Rat... | 9,851,736 | [['B01.050'], ['D27.505.954.158'], ['C05.550.114.015', 'E05.598.500.249'], ['D02.455.426.559.389.657.410.595.176'], ['A11.118.188', 'A15.145.229.188'], ['D02.455.426.559.389.657.410.595.303'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['A03.556.875.87... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cost containment through health promotion programs. | The multiple health promotion programs provided in the United States for the employees of a major office equipment manufacturer and the effect they are believed to have not only on cost containment but also on employee self-image, job satisfaction, company loyalty, morale and productivity are described. Specific attent... | ['Cost Control', 'Health Promotion', 'Humans', 'Occupational Health Services', 'Physical Fitness', 'United States'] | 7,153,803 | [['N03.219.151.160'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.143.740'], ['G11.427.685', 'I03.450.642.845.054.800', 'N01.400.545'], ['Z01.107.567.875']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[Surface-active properties of expirates in patients with acute pneumonia]. | Surface activity of expirates, expired vapours was studied in 143 male patients, aged 18 to 20 years with acute pneumonia (AP). A colorimetric procedure based on estimation of the intensity of sudan solubilization by lipids contained in expirate condensates was used. The control group included 30 patients with acute br... | ['Adolescent', 'Adult', 'Breath Tests', 'Humans', 'Male', 'Pneumonia, Pneumococcal', 'Pneumonia, Staphylococcal', 'Pulmonary Surfactants', 'Respiration', 'Respiratory Insufficiency'] | 2,336,436 | [['M01.060.057'], ['M01.060.116'], ['E01.370.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.410.890.670.750', 'C01.150.252.620.550', 'C01.748.610.540.550', 'C08.381.677.540.550', 'C08.730.610.540.550'], ['C01.150.252.410.868.675', 'C01.150.252.620.620', 'C01.748.610.540.620', 'C08.381.677.540.620... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Synthetic peptide TEKKRRETVEREKE derived from ezrin induces differentiation of NIH/3T3 fibroblasts. | Synthetic 14 AA peptide (Gepon) derived from the hinge region of ezrin, a protein that links cell surface molecules to intracellular actin filaments, accelerates and facilitates wound and ulcer healing in clinical applications. However, the molecular mechanisms underlying this phenomenon and involved in enhanced healin... | ['Amino Acid Sequence', 'Animals', 'Cell Differentiation', 'Cell Movement', 'Collagen Type I', 'Cytoskeletal Proteins', 'Fibroblasts', 'Gene Expression Regulation', 'Gene Knockout Techniques', 'Hyaluronan Receptors', 'Intracellular Space', 'Mice', 'NIH 3T3 Cells', 'Peptide Fragments', 'Proto-Oncogene Proteins c-fos', '... | 28,668,507 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G04.152'], ['G04.198', 'G07.568.500.180'], ['D05.750.078.280.300.100', 'D12.776.860.300.250.300.100'], ['D12.776.220'], ['A11.329.228'], ['G05.308'], ['E05.393.335.750'], ['D09.698.735.200.625', 'D12.776.395.550.200.625.144', 'D12.776.395.650.750.281', 'D12.77... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Women and pensions: a decade of progress? | This Issue Brief compares changes from 1989 to 1998 in pension participation, accumulation, and allocation for employed women, versus employed men, ages 18-62. In addition, it provides an estimate of the gender "pension gap" in defined contribution accumulations, contrasts this with the gender "earnings gap," and provi... | ['Adolescent', 'Adult', 'Cohort Studies', 'Decision Making', 'Employment', 'Female', 'Humans', 'Income', 'Investments', 'Male', 'Middle Aged', 'Pensions', 'Retirement', 'Risk-Taking', 'Sex Factors', 'Women, Working'] | 11,187,399 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['F02.463.785.373'], ['N01.824.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ['N03.219.702'], ['M01.060.116.630'], ['N01.824.417.510'], ['I03.702'], ['F01.145.722'], ['N05.715.350... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Indices for studying urinary incontinence and levator ani function in primiparous women. | Urinary incontinence (UI) is a complex phenomenon that is prevalent in pregnant and parous women and requires the use of sophisticated measures to adequately reflect functioning of the continence system. The purpose of this study was to develop reliable and valid measures of UI and levator ani function for use in resea... | ['Adolescent', 'Adult', 'Female', 'Follow-Up Studies', 'Gestational Age', 'Humans', 'Longitudinal Studies', 'Neonatal Nursing', 'Nursing Research', 'Parity', 'Pelvic Floor', 'Postpartum Period', 'Pregnancy', 'Prevalence', 'Probability', 'Risk Assessment', 'Risk Factors', 'Sampling Studies', 'Severity of Illness Index',... | 12,790,869 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['H02.478.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[The quality of analgesia in relation to the plasma concentration of beta-endorphin during neuroleptanalgesia and epidural analgesia]. | In 66 patients who had to undergo radical abdominal hysterectomy because of cancer of the cervix uteri, the plasma concentrations of beta-endorphin were observed intra- and postoperatively. Two anaesthetic techniques were used: neuroleptanalgesia and thoracolumbar epidural analgesia with sedation and controlled inhalat... | ['Analgesia, Epidural', 'Female', 'Humans', 'Neuroleptanalgesia', 'beta-Endorphin'] | 2,144,117 | [['E03.091.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E03.091.646'], ['D06.472.699.327.935.239', 'D06.472.699.631.525.600.239', 'D12.644.400.400.935.239', 'D12.644.400.575.241.080', 'D12.644.548.365.935.239', 'D12.644.548.691.525.690.239', 'D12.776.631.650.405.935.239', 'D12.776.631.650.575.241.080']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
HIV-1 exposed dendritic cells show increased pro-inflammatory cytokine production but reduced IL-1ra following lipopolysaccharide stimulation. | OBJECTIVES: Dendritic cells (DC) are potential first target cells in sexually transmitted HIV-1 infection. They are also considered to be central in the activation of naive T cells, which thereupon can become permissive for HIV-1. In addition, activated DC express effector molecules, which likely contribute to the dire... | ['Cells, Cultured', 'Chemokines', 'Cytokines', 'DNA, Viral', 'Dendritic Cells', 'Genes, gag', 'HIV Infections', 'HIV-1', 'Humans', 'Interleukin 1 Receptor Antagonist Protein', 'Interleukin-1', 'Lipopolysaccharides', 'Receptors, Interleukin', 'Sialoglycoproteins', 'Tumor Necrosis Factor-alpha', 'Virus Replication'] | 10,546,853 | [['A11.251'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D13.444.308.568'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['G05.360.340.024.340.364.875.258', 'G05.360.340.358.024.875.25... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Design of Aerogels, Cryogels and Xerogels of Alginate: Effect of Molecular Weight, Gelation Conditions and Drying Method on Particles' Micromeritics. | Processing and shaping of dried gels are of interest in several fields like alginate aerogel beads used as highly porous and nanostructured particles in biomedical applications. The physicochemical properties of the alginate source, the solvent used in the gelation solution and the gel drying method are key parameters ... | ['Alginates', 'Cryogels', 'Drug Carriers', 'Drug Compounding', 'Freeze Drying', 'Gels', 'Humans', 'Molecular Weight', 'Nanostructures', 'Porosity'] | 30,884,869 | [['D09.698.068'], ['D20.280.320.375.500', 'D26.255.165.320.375.187'], ['D26.255.260', 'E02.319.300.380'], ['E05.916.270'], ['E01.370.225.500.620.760.160.260', 'E01.370.225.750.600.760.160.260', 'E02.792.156.260', 'E05.200.500.620.760.160.260', 'E05.200.750.600.760.160.260', 'E05.760.156.260'], ['D20.280.320', 'D26.255.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Hypogangliosis of the sigmoid colon: possibilities of sonographic diagnosis]. | This case report concerns a 53-year old woman suffering from recurrent spastic pain and a painful "resistance" in the left lower bowel for the last 30 years. Earlier clinical investigations including endoscopy and laparoscopy did not yield any results. In a recent investigation, only sonography showed wall thickening a... | ['Female', 'Hirschsprung Disease', 'Humans', 'Middle Aged', 'Muscle, Smooth', 'Sigmoid Diseases', 'Ultrasonography'] | 1,502,536 | [['C06.198.439', 'C06.405.469.158.701.439', 'C16.131.314.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.570', 'A10.690.467'], ['C06.405.469.158.850'], ['E01.370.350.850']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Therapeutic potential of the translation inhibitor silvestrol in hepatocellular cancer. | BACKGROUND & AIMS: Although hepatocellular cancers (HCC) frequently arise in the setting of fibrosis and a hepatic regenerative response requiring new cell growth, therapeutic strategies for these cancers have not targeted protein synthesis. Silvestrol, a rocaglate isolated from Aglaiafoveolata, can inhibit protein syn... | ['Analysis of Variance', 'Animals', 'Apoptosis', 'Blotting, Western', 'Caspase 3', 'Caspase 7', 'Cell Line, Tumor', 'Cell Proliferation', 'Dose-Response Relationship, Drug', 'Drug Synergism', 'Eukaryotic Initiation Factor-4A', 'Humans', 'Inhibitory Concentration 50', 'Liver Neoplasms', 'Membrane Potential, Mitochondria... | 24,086,701 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.77... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Helicobacter pylori and gastric cancer in view of relation to atrophy of background gastric mucosa]. | To make clinical assessment regarding the role of Helicobacter pylori (H. pylori) in the occurrence of gastric cancer, we examined serological and microbiological positive rate of H. pylori and histological and endoscopic findings of atrophic gastritis of background mucosa in 149 gastric cancer patients, 136 gastric ul... | ['Atrophy', 'Female', 'Gastric Mucosa', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Male', 'Middle Aged', 'Stomach Neoplasms'] | 8,283,641 | [['C23.300.070'], ['A03.556.875.875.440', 'A10.615.550.291'], ['C01.150.252.400.466'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C06.405.748.789']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The environmental history of Chatthin Wildlife Sanctuary, a protected area in Myanmar (Burma). | We reconstructed the history of Chatthin Wildlife Sanctuary (CWS) to understand how social and economic events, and policy changes affected the sanctuary's condition. We surveyed 25 villages surrounding CWS to evaluate past and present ecological conditions, compare the results with historical accounts and identify cau... | ['Animals', 'Animals, Domestic', 'Animals, Wild', 'Conservation of Natural Resources', 'Data Collection', 'Ecology', 'Environment', 'Forestry', 'History, 20th Century', 'Humans', 'Myanmar', 'Policy Making', 'Population Dynamics', 'Social Conditions'] | 15,294,353 | [['B01.050'], ['B01.050.050.116'], ['B01.050.050.300'], ['J01.256', 'N06.230.080'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['H01.158.273.248', 'H01.277.249'], ['G16.500.275', 'N06.230'], ['J01.576.430'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.145.5... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Humanities [K]', 'Geographicals [Z]', 'Anthropology, Education, Sociolog... | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 |
Relations between emotional and social functioning in children with anxiety disorders. | The current study investigated concurrent relations between emotional and social functioning in youth with anxiety disorders using a multi-reporter (i.e., children, parents, teachers) assessment strategy. Ninety youth (M age = 8.98 years, SD = 1.68) with a primary diagnosis of generalized anxiety disorder, social phobi... | ['Adaptation, Psychological', 'Anxiety Disorders', 'Anxiety, Separation', 'Child', 'Emotions', 'Female', 'Humans', 'Male', 'Parents', 'Peer Group', 'Social Adjustment'] | 24,258,408 | [['F01.058'], ['F03.080'], ['F03.080.300', 'F03.625.047'], ['M01.060.406'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['F01.829.316.483'], ['F01.145.813.621']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Usefulness of respiratory variation of inferior vena cava diameter for estimation of elevated central venous pressure in children with cardiovascular disease. | BACKGROUND: The purpose of the present study was to determine the relationship of inferior vena cava diameter (IVCD) and its respirophasic variation (IVC collapsibility index: IVCCI) with central venous pressure (CVP), and thereby to provide reference cut-offs for such IVC parameters to estimate elevation in CVP in ped... | ['Cardiovascular Diseases', 'Catheterization, Central Venous', 'Central Venous Pressure', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'ROC Curve', 'Respiration', 'Ultrasonography', 'Vena Cava, Inferior'] | 21,372,405 | [['C14'], ['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['G09.330.380.076.732.336'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.800.750', 'E05.318.740.872.750', 'N05.715.360.325.700.680', 'N06.850.520.445.800.750'], ['G09.772.705'], [... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Control of apoptosis during angiogenesis by survivin expression in endothelial cells. | Mechanisms controlling endothelial cell survival during angiogenesis were investigated. Stimulation of quiescent endothelial cells with mitogens, including vascular endothelial growth factor and basic fibroblast growth factor, induced up to approximately 16-fold up-regulation of the cell cycle-regulated apoptosis inhib... | ['Apoptosis', 'Cell Division', 'Cell Survival', 'Cells, Cultured', 'Endothelial Growth Factors', 'Endothelium, Vascular', 'Fibroblast Growth Factor 2', 'Humans', 'Inhibitor of Apoptosis Proteins', 'Lymphokines', 'Microtubule-Associated Proteins', 'Mitogens', 'Neoplasm Proteins', 'Neovascularization, Physiologic', 'Prot... | 10,666,367 | [['G04.146.954.035'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.346'], ['A11.251'], ['D12.644.276.390', 'D12.776.467.390', 'D23.529.390'], ['A07.015.700.500', 'A10.272.491.355'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['B01.050.150.900.649.313.988.400.11... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor. | The recent molecular cloning of the complementary DNA encoding T cell--replacing factor (TRF) has demonstrated that a single molecule is responsible for B cell growth factor II (BCGF-II) activity and eosinophil differentiation activity. It has been proposed that this molecule be called interleukin 5 (IL-5). We previous... | ['Animals', 'Cell Survival', 'Cells, Cultured', 'Chemotactic Factors', 'Eosinophils', 'Female', 'Interleukin-5', 'Interleukins', 'Mice', 'Mice, Inbred BALB C', 'Recombinant Proteins', 'Superoxides'] | 2,835,420 | [['B01.050'], ['G04.346'], ['A11.251'], ['D23.125'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['D12.644.276.374.465.202', 'D12.776.467.374.465.186', 'D23.529.374.465.202'], ['D12.644.276.374.465', 'D12.776.467.374.465', 'D23.529.374.465'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chronic performance of a leadless cardiac pacemaker: 1-year follow-up of the LEADLESS trial. | BACKGROUND: A leadless cardiac pacemaker (LCP) system was recently introduced to overcome lead-related complications of conventional pacing systems. To date, long-term results of an LCP system are unknown.OBJECTIVES: The aim of this study was to assess the complication incidence, electrical performance, and rate respon... | ['Aged', 'Arrhythmias, Cardiac', 'Cardiac Pacing, Artificial', 'Equipment Design', 'Equipment Safety', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Pacemaker, Artificial', 'Retrospective Studies'] | 25,881,930 | [['M01.060.116.100'], ['C14.280.067', 'C23.550.073'], ['E02.331.200'], ['E05.320'], ['E05.330'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.305.250.750'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.71... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Block modification of rod-shaped pi conjugated carbon frameworks with donor and acceptor groups toward highly fluorescent molecules: synthesis and emission characteristics. | To create organic molecules that are highly fluorescent at a longer wavelength region, we investigated the synthesis (using Pd-catalyzed cross-coupling) and photophysical properties (Phi(f), lambda(em), tau, lambda(abs), and epsilon) of the following pi conjugated molecular rods consisting of p-phenyleneethynylene unit... | ['Fluorescent Dyes', 'Luminescence', 'Molecular Structure', 'Organic Chemicals', 'Photochemistry'] | 18,362,962 | [['D27.720.233.348', 'D27.720.470.410.505.500'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.750.250.650.665', 'G01.750.770.578.665'], ['G02.111.570', 'G02.466'], ['D02'], ['H01.181.529.711']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[The outpatient care in the Latium region (Italy) in 2001]. | The Region of Latium has been operating an Outpatient Care Information System (SIAS) since 1997 to monitor the supply of outpatient care in a territory with a population of over five million. The present work has the aim of describing the outpatient care in the region, in terms of number of facilities involved by categ... | ['Ambulatory Care Facilities', 'Catchment Area, Health', 'Humans', 'Italy', 'Medicine', 'Private Sector', 'Public Sector', 'Rome', 'Specialization', 'Utilization Review'] | 15,554,509 | [['N02.278.035'], ['N01.224.791.200', 'N03.349.650.095', 'N06.850.505.400.800.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['H02.403'], ['I01.791', 'N04.452.633.390'], ['I01.795', 'N04.452.633.890'], ['Z01.433.850', 'Z01.542.489.569'], ['H02.811'], ['N04.761.879', 'N05.700.900']] | ['Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Hyperhomocysteinemia is associated with atherosclerotic occlusive arterial accidents in predialysis chronic renal failure patients. | Hyperhomocysteinemia has been shown to constitute an independent risk factor for premature occlusive arterial disease. Moderate hyperhomocysteinemia is present in chronic uremic patients, who often develop premature atherosclerosis, but no direct evidence of an association between the occurrence of atherosclerotic card... | ['Aged', 'Arteriosclerosis', 'Female', 'Homocysteine', 'Humans', 'Kidney Failure, Chronic', 'Logistic Models', 'Male', 'Middle Aged', 'Prospective Studies', 'Regression Analysis', 'Renal Dialysis', 'Uremia'] | 9,387,110 | [['M01.060.116.100'], ['C14.907.137.126'], ['D02.886.030.498', 'D12.125.166.498'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cytologic features of seminal vesicle epithelium in aspiration biopsy smears of the prostate. | To determine the rate of occurrence of cells derived from seminal vesicles in routine needle aspirates of the prostate, the smears of 853 aspirates were reviewed. The cytologic features of cells originating from the seminal vesicles were described using air-dried smears stained by the May-Gr?nwald-Giemsa method. The di... | ['Biopsy, Needle', 'Cytodiagnosis', 'Diagnosis, Differential', 'Epithelial Cells', 'False Positive Reactions', 'Humans', 'Male', 'Prostate', 'Prostatic Neoplasms', 'Seminal Vesicles', 'Specimen Handling'] | 1,065,171 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['E01.370.225.500.384', 'E05.200.500.384', 'E05.242.384'], ['E01.171'], ['A11.436'], ['E01.354.506'], ['B01.050.150.900.649.313.988.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[PREDICTORS OF MODERATE COGNITIVE DISORDERS IN PATIENTS WITH CORONARY HEART DISEASE AND TYPE 2 DIABETES MELLITUS]. | AIM: To study predictors of moderate cognitive disorders (MCD) in patients with coronary heart disease (CHD) and type 2 diabetes mellitus (DM2).MATERIALS AND METHODS: The study included 54 men with CPD andDM2 (mean age 56.8 ± 4.5 years). Standard medical examination was supplemented by the assessment of cognitive statu... | ['Age Factors', 'Aged', 'Carbohydrate Metabolism', 'Cognition Disorders', 'Coronary Artery Disease', 'Diabetes Mellitus, Type 2', 'Educational Status', 'Fructosamine', 'Glycated Hemoglobin A', 'Humans', 'Insulin', 'Lipid Metabolism', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'ROC Curve', 'Risk Factors'] | 27,172,719 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['G02.111.158', 'G03.191'], ['F03.615.250'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['C18.452.394.750.149', 'C19.246.300'], ['N01.824.196'], ['D09.067.342.300'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381'... | ['Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Heterogeneous localization of epitopes along axonemes of mammalian cilia. | The specificity of four monoclonal antibodies, raised against mammalian ciliary axonemes, was determined by both immunofluorescence and immunoblot experiments. Three antibodies reacted with epitopes which are differentially located along axonemal length. Among these, antibody 3.12 recognized an epitope common to differ... | ['Animals', 'Antibodies, Monoclonal', 'Cattle', 'Cilia', 'Immunoenzyme Techniques', 'In Vitro Techniques', 'Molecular Weight', 'Trachea'] | 7,549,913 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['B01.050.150.900.649.313.500.380.271'], ['A11.284.180.165'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['E05.481'], ['G02.494'], ['A04.889']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
3D reconstruction of the brain from magnetic resonance images using a connectivity algorithm. | We present high resolution three dimensional (3D) connectivity, surface construction and display algorithms that detect, extract, and display the surface of a brain from contiguous magnetic resonance (MR) images. The algorithms identify the external brain surface and create a 3D image, showing the fissures and surface ... | ['Adult', 'Algorithms', 'Brain', 'Female', 'Humans', 'Image Enhancement', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging'] | 3,695,821 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['L01.224.308'], ['E01.370.350.825.500']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Erythrocyte hyperaggregation in obesity: determining factors and weight loss influence. | OBJECTIVE: To compare erythrocyte aggregation (EA) in patients with severe obesity without other cardiovascular risk factors with a control group, using the Myrenne and the Sefam aggregometers, and to evaluate the effect of weight loss on this parameter.RESEARCH METHODS AND PROCEDURES: This was a longitudinal, clinical... | ['Adult', 'Blood Glucose', 'C-Reactive Protein', 'Cholesterol', 'Erythrocyte Aggregation', 'Female', 'Fibrinogen', 'Humans', 'Insulin', 'Insulin Resistance', 'Male', 'Middle Aged', 'Obesity', 'Statistics, Nonparametric', 'Triglycerides', 'Weight Loss'] | 17,712,132 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['E01.370.225.625.225', 'E05.200.625.225', 'G09.188.370.187'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Safety and efficacy of various regimens of heparin-mediated prevention of venous thromboses in patients with intracranial haemorrhage]. | Analysed in the article is the incidence rate of the development of venous thromboembolic complications in a total of 79 patients presenting with various-aetiology intracranial haemorrhage in different regimens of heparin-mediated prevention. The authors have revealed that early (on day 2-4 after the onset of the disea... | ['Aged', 'Anticoagulants', 'Blood Coagulation', 'Chemoprevention', 'Drug Monitoring', 'Early Medical Intervention', 'Female', 'Heparin, Low-Molecular-Weight', 'Humans', 'Intracranial Hemorrhages', 'Male', 'Middle Aged', 'Partial Thromboplastin Time', 'Retrospective Studies', 'Treatment Outcome', 'Ultrasonography', 'Ven... | 22,836,324 | [['M01.060.116.100'], ['D27.505.954.502.119'], ['G09.188.390.150'], ['E02.319.162'], ['E01.370.520.200'], ['N02.421.726.363'], ['D09.698.373.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.535', 'C14.907.253.573', 'C23.550.414.913'], ['M01.060.116.630'], ['E01.370.225.625.115.600', 'E05.20... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dual role of tumor suppressor p53 in regulation of DNA replication and oncogene E6-promoter activity of epidermodysplasia verruciformis-associated human papillomavirus type 8. | Human papillomavirus 8 (HPV8) is a representative of Epidermodysplasia verruciformis (EV)-associated viruses. Transient assays in the human skin keratinocyte cell line RTS3b have shown that its replication depends in trans on expression of the viral proteins E1 and E2, similarly to other HPVs. Using deletion mutants an... | ['Binding Sites', 'Cell Line', 'DNA Replication', 'Epidermodysplasia Verruciformis', 'Humans', 'Oncogene Proteins, Viral', 'Papillomaviridae', 'Promoter Regions, Genetic', 'Tumor Suppressor Protein p53', 'Virus Replication'] | 12,706,078 | [['G02.111.570.120'], ['A11.251.210'], ['G02.111.225', 'G05.226'], ['C01.925.256.650.810.345', 'C01.925.825.810.260', 'C01.925.928.914.345', 'C17.800.838.790.810.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.624.664.520', 'D12.776.964.700'], ['B04.280.210.655', 'B04.613.204.655'], ['G02.111.570.080.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
National outbreak of Salmonella serotype saintpaul infections: importance of Texas restaurant investigations in implicating jalape?o peppers. | BACKGROUND: In May 2008, PulseNet detected a multistate outbreak of Salmonella enterica serotype Saintpaul infections. Initial investigations identified an epidemiologic association between illness and consumption of raw tomatoes, yet cases continued. In mid-June, we investigated two clusters of outbreak strain infecti... | ['Adolescent', 'Adult', 'Aged', 'Capsicum', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Disease Outbreaks', 'Female', 'Humans', 'Male', 'Middle Aged', 'Research Report', 'Restaurants', 'Salmonella Food Poisoning', 'Salmonella Infections', 'Salmonella enterica', 'Serotyping', 'Texas', 'Young Adult'] | 21,373,185 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.650.940.800.575.912.250.908.500.145'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['N06.850.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H01.770.644.8... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 |
A rapid method for the detection of potentially viable Mycobacterium leprae in human biopsies: a novel application of PCR. | A simple procedure based on the polymerase chain reaction has been developed to detect Mycobacterium leprae, rapidly and unambiguously, in biological samples. Its application to small numbers of M. leprae cells (approximately 10(2] isolated from armadillo liver, mouse footpads or human biopsies is discussed. | ['Animals', 'Biopsy', 'Blotting, Southern', 'DNA, Bacterial', 'Electrophoresis, Agar Gel', 'Gene Amplification', 'Humans', 'Kinetics', 'Leprosy', 'Mycobacterium leprae', 'Polymerase Chain Reaction', 'Repetitive Sequences, Nucleic Acid'] | 2,693,204 | [['B01.050'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['D13.444.308.212'], ['E05.196.401.153', 'E05.301.300.100'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Applying Rprop neural network for the prediction of the mobile station location. | Wireless location is the function used to determine the mobile station (MS) location in a wireless cellular communications system. When it is very hard for the surrounding base stations (BSs) to detect a MS or the measurements contain large errors in non-line-of-sight (NLOS) environments, then one need to integrate all... | ['Algorithms', 'Humans', 'Neural Networks, Computer', 'Wireless Technology'] | 22,163,844 | [['G17.035', 'L01.224.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17.485', 'L01.224.050.375.605'], ['L01.178.847.950']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Cloning and sequencing of equine transforming growth factor-beta 1 (TGF beta-1) cDNA. | Transforming growth factor beta (TGF-beta) belongs to a family of peptide growth factors which control critical stages of cell proliferation and differentiation. We report the cloning and sequencing of the cDNA for TGF-beta type 1 isoform of the horse. The predicted mature equine TGF beta-1 peptide is 112 amino acids i... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cloning, Molecular', 'Horses', 'Humans', 'Molecular Sequence Data', 'Sequence Analysis', 'Sequence Homology, Amino Acid', 'Sequence Homology, Nucleic Acid', 'Transforming Growth Factor beta'] | 9,524,819 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['B01.050.150.900.649.313.984.235.472'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['E05.393.760'], ['G02.111.810.200', 'G05.810.200'], ['G02.111.810.550', 'G... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Engineered Disease Resistance in Cotton Using RNA-Interference to Knock down Cotton leaf curl Kokhran virus-Burewala and Cotton leaf curl Multan betasatellite Expression. | Cotton leaf curl virus disease (CLCuD) is caused by a suite of whitefly-transmitted begomovirus species and strains, resulting in extensive losses annually in India and Pakistan. RNA-interference (RNAi) is a proven technology used for knockdown of gene expression in higher organisms and viruses. In this study, a small ... | ['Begomovirus', 'DNA, Satellite', 'DNA, Viral', 'Disease Resistance', 'Gene Knockdown Techniques', 'Genetic Engineering', 'Gossypium', 'In Situ Hybridization, Fluorescence', 'Phylogeny', 'Plant Diseases', 'Plants, Genetically Modified', 'RNA Interference', 'Real-Time Polymerase Chain Reaction', 'Satellite Viruses', 'Se... | 28,906,473 | [['B04.280.350.100', 'B04.715.270.100'], ['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.360.340.024.220.150', 'G05.360.340.024.850.150'], ['D13.444.308.568'], ['C23.550.291.671', 'G12.450.564.250', 'G12.450.800.250', 'G15.630.250'], ['E05.393.335.500'], ['E05.393.420'], ['B01.650.940... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Inhibition of gastric mucosal mucin receptor by H. pylori lipopolysaccharide: effect of ebrotidine. | 1. H. pylori infection causes the loss of mucus coat continuity and its patchy appearance. Here, we present evidence that the bacterium, through its cell wall lipopolysaccharide, disrupts the interaction between mucin and its mucosal receptor, and that ebrotidine is capable of counteracting this process. 2. The recepto... | ['Animals', 'Anti-Ulcer Agents', 'Benzenesulfonates', 'Gastric Mucins', 'Helicobacter pylori', 'Lipopolysaccharides', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Cell Surface', 'Thiazoles'] | 8,690,245 | [['B01.050'], ['D27.505.954.483.203'], ['D02.455.426.559.389.097', 'D02.886.645.600.080.050.100'], ['D12.776.395.560.631.100'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quality of reporting in evaluations of surgical treatment of trigeminal neuralgia: recommendations for future reports. | OBJECTIVE: There are numerous reports on the surgical treatment of trigeminal neuralgia, but the studies do not use uniform outcome measures, which makes it difficult for patients and clinicians to determine which treatment may be most appropriate. The objectives of this study were to set quality criteria and standards... | ['Clinical Protocols', 'Evaluation Studies as Topic', 'Humans', 'Neurosurgical Procedures', 'Outcome Assessment, Health Care', 'Reference Standards', 'Reproducibility of Results', 'Research Design', 'Trigeminal Neuralgia'] | 12,823,880 | [['E02.183', 'N05.715.360.330.125'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.525'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['E05.978.808'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.581.500', 'H01.77... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[Granulomatosis with polyangiitis (Wegener). Description of 15 cases]. | BACKGROUND: Granulomatosis with polyangiitis (GP) is a necrotizing vasculitis of unknown etiology that involves small and medium caliber vessels. It is associated with anti neutrophil cytoplasm antibodies (ANCA). It most often affects the respiratory tract and the kidneys and its most important pathologic feature is th... | ['Adolescent', 'Adult', 'Aged', 'Female', 'Granulomatosis with Polyangiitis', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Young Adult'] | 22,089,070 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C08.381.483.950', 'C14.907.940.897.249.750', 'C20.111.193.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.5... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transpositions of mobile dispersed genes in Drosophila melanogaster and fitness of stocks. | In situ hybridization with polytene chromosomes was used to demonstrate the transposition of mobile dispersed genes (mdg)-1 and 3 following the selection of flies from low reproductive activity and viability (LA stock) for high reproductive activity, viability and fitness (LA+ and HA stocks). The inbred LA stock is con... | ['Animals', 'Chromosome Mapping', 'Drosophila melanogaster', 'Genes', 'Nucleic Acid Hybridization', 'Recombination, Genetic', 'Selection, Genetic'] | 6,806,565 | [['B01.050'], ['E05.393.183'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.360.340.024.340'], ['E05.393.661', 'G02.111.611'], ['G05.728'], ['G05.783']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activation of human Valpha24NKT cells by alpha-glycosylceramide in a CD1d-restricted and Valpha24TCR-mediated manner. | Vact14NK(natural killer) T cells play an important role in controlling tumors or in preventing autoimmunity in the murine system. Valpha24NKT cells, the human counterpart of Valpha14NKT cells, may contribute to controlling the progression of autoimmune diseases in humans. These findings show the possibility that ligand... | ['Antigens, CD1', 'Cell Line', 'Ceramides', 'Humans', 'Immunophenotyping', 'Killer Cells, Natural', 'Lymphocyte Activation', 'Receptors, Antigen, T-Cell', 'Receptors, Antigen, T-Cell, alpha-beta'] | 9,952,023 | [['D23.050.301.264.035.100', 'D23.050.301.264.894.080', 'D23.101.100.110.100', 'D23.101.100.894.080'], ['A11.251.210'], ['D02.065.313', 'D09.400.410.420.525.200', 'D10.390.470.675.200', 'D10.570.877.360.612.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.594.4... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ocular findings in subacute sclerosing panencephalitis. | PURPOSE: The aim of this study was to evaluate the ocular manifestations of subacute sclerosing panencephalitis (SSPE) and to investigate possible risk factors in a relatively large series of patients.METHODS: In this prospective study, patients who were diagnosed with SSPE and had undergone ophthalmic examination were... | ['Child', 'Child, Preschool', 'Chorioretinitis', 'Edema', 'Female', 'Humans', 'Macula Lutea', 'Male', 'Optic Atrophy', 'Optic Nerve Diseases', 'Prospective Studies', 'Retinal Pigment Epithelium', 'Retinal Vessels', 'Risk Factors', 'Subacute Sclerosing Panencephalitis'] | 21,428,756 | [['M01.060.406'], ['M01.060.406.448'], ['C11.768.773.348', 'C11.941.160.478.400', 'C11.941.879.780.900.300.318'], ['C23.888.277'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.729.522'], ['C10.292.700.225', 'C11.640.451'], ['C10.292.700', 'C11.640'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.65... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A fluorescence-based high-performance liquid chromatographic assay to determine acid ceramidase activity. | Acid ceramidase (N-acylsphingosine amidohydrolase) is the lysosomal enzyme required to hydrolyze the N-acyl linkage between the fatty acid and sphingosine moieties in ceramide. A deficiency of acid ceramidase activity results in the lipid storage disorder, Farber disease. This study reports a new assay method to detect... | ['Acid Ceramidase', 'Amidohydrolases', 'Animals', 'Cell Line', 'Ceramidases', 'Chromatography, High Pressure Liquid', 'Fibroblasts', 'Fluorescence', 'Humans', 'Lysosomal Storage Diseases', 'Mice', 'Skin'] | 10,527,524 | [['D08.811.277.087.250.100'], ['D08.811.277.087'], ['B01.050'], ['A11.251.210'], ['D08.811.277.087.250'], ['E05.196.181.400.300'], ['A11.329.228'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.565.595', 'C18.452.648.595'], ['B01.050.150.900.649.313.9... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
TMJ disorders and pain: assessment by contrast-enhanced MRI. | Though magnetic resonance (MRI) is a widely accepted standard for the assessment of patients with temporomandibular joint (TMJ) disorders, efforts to correlate symptoms to MRI findings have often given controversial results. Aim of this study was to investigate the correlation between TMJ pain and findings of contrast-... | ['Arthralgia', 'Contrast Media', 'Female', 'Gadolinium DTPA', 'Humans', 'Image Enhancement', 'Magnetic Resonance Imaging', 'Male', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Temporomandibular Joint Disorders'] | 18,329,212 | [['C05.550.091', 'C23.888.592.612.094', 'F02.830.816.444.350', 'G11.561.790.444.350'], ['D27.505.259.500', 'D27.720.259'], ['D02.092.782.590.401', 'D02.241.081.018.639.400', 'D02.257.141'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.370.350.825.500'], ['E05.318.37... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Assembly of vaccinia virus: effects of rifampin on the intracellular distribution of viral protein p65. | The cytoplasmic assembly of vaccinia virus is reversibly blocked by the antibiotic rifampin, leading to the accumulation of partially membrane-delineated rifampin bodies in infected cells. Rifampin-resistant vaccinia virus mutants have point mutations in the D13L gene, which is controlled by a late promoter and express... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Viral', 'Cell Compartmentation', 'Cells, Cultured', 'Humans', 'Immunohistochemistry', 'Inclusion Bodies, Viral', 'Intracellular Membranes', 'Microscopy, Immunoelectron', 'Molecular Sequence Data', 'Peptide Fragments', 'Protein Denaturation', 'Rifampin', 'Vaccinia virus', ... | 8,289,340 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['G04.128'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Cardiovascular and metabolic characteristics of infertile Chinese women with PCOS diagnosed according to the Rotterdam consensus criteria. | Polycystic ovary syndrome (PCOS) is strongly associated with metabolic abnormalities in Western women. However, data from other populations and geographical regions are scarce. This study evaluated cardiovascular and metabolic risk factors in Chinese infertile women diagnosed with PCOS using the 2003 Rotterdam consensu... | ['Adult', 'Anovulation', 'Asian Continental Ancestry Group', 'Cardiovascular Diseases', 'China', 'Female', 'Glucose', 'Hirsutism', 'Humans', 'Hyperandrogenism', 'Lipid Metabolism', 'Metabolic Syndrome', 'Phenotype', 'Polycystic Ovary Syndrome'] | 20,800,551 | [['M01.060.116'], ['C13.351.500.056.630.050', 'C19.391.630.050', 'G08.686.784.690.080'], ['M01.686.508.200'], ['C14'], ['Z01.252.474.164'], ['D09.947.875.359.448'], ['C17.800.329.750', 'C23.888.971.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.706.316.064.500', 'C12.706.316.090.750', 'C13.351.875.253.06... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
A novel quantitative trait locus on chromosome 1 with pleiotropic effects on HDL-cholesterol and LDL particle size in hypertensive sibships. | BACKGROUND: High-density lipoprotein (HDL)-cholesterol, triglycerides, and LDL particle size are correlated lipid traits. Abnormal levels of these traits are frequent in hypertensive individuals and contribute to increased risk of coronary heart disease (CHD). We performed univariate and bivariate linkage analyses to i... | ['Aged', 'Cholesterol, HDL', 'Chromosome Mapping', 'Chromosomes, Human, Pair 1', 'Female', 'Genetic Linkage', 'Genotype', 'Humans', 'Hypertension', 'Lipoproteins, LDL', 'Lod Score', 'Male', 'Middle Aged', 'Particle Size', 'Quantitative Trait Loci', 'Siblings', 'Statistics as Topic', 'Triglycerides'] | 16,109,322 | [['M01.060.116.100'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['E05.393.183'], ['A11.284.187.520.300.235.240', 'G05.360.162.520.300.235.240'], ['G05.348'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['D10.532.515', 'D12.776.52... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupat... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Physicians' and midlevel providers' awareness of lifetime radiation-attributable cancer risk associated with commonly performed CT studies: relationship to practice behavior. | OBJECTIVE: The purpose of this study is to investigate emergency department (ED) providers' knowledge of the lifetime cancer risk attributable to radiation from commonly performed CT scans and its association with the ordering providers' risk-benefit analysis before ordering the examination. This study further explores... | ['Adult', 'Aged', 'Clinical Competence', 'Cross-Sectional Studies', 'Decision Making', 'Emergency Service, Hospital', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Neoplasms, Radiation-Induced', 'Radiography, Abdominal', 'Risk', 'Surveys and Questionnaires', 'To... | 23,169,726 | [['M01.060.116'], ['M01.060.116.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F02.463.785.373'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.9... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) trial programme; rationale, design and baseline characteristics including a meta-analysis of the effects of thienopyridines in vascular disease. | BACKGROUND: Other than aspirin, there are few oral antithrombotic treatments with proven efficacy in patients with acute coronary syndrome. In this report, we present the rationale, design and baseline characteristics of the Clopidogrel in Unstable angina to prevent Recurrent ischaemic Events (CURE) trial, which includ... | ['Angina, Unstable', 'Aspirin', 'Clopidogrel', 'Humans', 'Meta-Analysis as Topic', 'Platelet Aggregation Inhibitors', 'Randomized Controlled Trials as Topic', 'Ticlopidine', 'Vascular Diseases'] | 11,102,254 | [['C14.280.647.187.150', 'C14.907.585.187.150', 'C23.888.592.612.233.500.150'], ['D02.455.426.559.389.657.410.595.176'], ['D02.886.778.823.500.500', 'D03.383.725.849.500.500', 'D03.383.903.830.500.500', 'D03.633.100.928.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.500', 'E05.581.500.501', '... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Morphohistological aspects of tumors and tumor-like changes in the thyroid gland]. | The results of the thyroid gland (TG) state investigation in 1027 patients, ageing from 14 to 75 years, operated on in 1986-1995 yrs., are adduced. In 60.5% of patients the diffuse-nodular goitre was diagnosed, in 9.5%--Hashimoto's thyroiditis, in 9.5%--TG cancer, in 2.8%--other pathology. To establish the interrelatio... | ['Adenocarcinoma, Follicular', 'Adolescent', 'Adult', 'Aged', 'Goiter, Nodular', 'Humans', 'Middle Aged', 'Precancerous Conditions', 'Thyroid Gland', 'Thyroid Neoplasms', 'Thyroiditis, Autoimmune'] | 9,615,002 | [['C04.557.470.200.025.060'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C19.874.283.501'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.834'], ['A06.300.900'], ['C04.588.322.894', 'C04.588.443.915', 'C19.344.894', 'C19.874.788'], ['C19.874.871.102', 'C20.111.809']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Tuning structural durability of yeast-encapsulating alginate gel beads with interpenetrating networks for sustained bioethanol production. | Microorganisms have become key components in many biotechnological processes to produce various chemicals and biofuels. The encapsulation of microbial cells in calcium cross-linked alginate gel beads has been extensively studied due to several advantages over using free cells. However, industrial use of alginate gel be... | ['Alginates', 'Biotechnology', 'Calcium', 'Cells, Immobilized', 'Ethanol', 'Gels', 'Glucuronic Acid', 'Hexuronic Acids', 'Saccharomyces cerevisiae'] | 21,732,329 | [['D09.698.068'], ['H01.158.550', 'J01.897.120'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.270'], ['D02.033.375'], ['D20.280.320', 'D26.255.165.320'], ['D02.241.081.844.915.162.249', 'D02.241.152.811.162.500', 'D02.241.511.902.915.162.500', 'D09.811.922.162.500'], ['D02.241.081.844.915.400', 'D02.24... | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Resin-composite cytotoxicity varies with shade and irradiance. | OBJECTIVES: The study was aimed at investigating the cytotoxicity of different composites as a function of composite shade and the light curing unit (LCU) employed.METHODS: Non-polymerized and polymerized samples of the composites Grandio(®) (VOCO, Cuxhaven), Solitaire(®) (Heraeus Kulzer, Hanau) and Filtek Z 250(®) (3M... | ['Adult', 'Analysis of Variance', 'Cell Survival', 'Cells, Cultured', 'Color', 'Composite Resins', 'Curing Lights, Dental', 'Female', 'Fibroblasts', 'Gingiva', 'Humans', 'Light-Curing of Dental Adhesives', 'Statistics, Nonparametric'] | 22,240,279 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G04.346'], ['A11.251'], ['G01.590.540.199'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.186.104', 'E07.222.104'], ['A11.329.228'], ['A14.549.167.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Pregnancies complicated by diabetes--North Dakota, 1980-1992. | Women with established diabetes mellitus (EDM) or gestational diabetes mellitus (GDM) are at increased risk for maternal complications during pregnancy; infants born to women with diabetes also are at increased risk for adverse outcomes, including infant death, congenital malformation, birth injury, and hyaline membran... | ['Adult', 'Birth Certificates', 'Diabetes, Gestational', 'Female', 'Humans', 'Maternal Age', 'North Dakota', 'Population Surveillance', 'Pregnancy', 'Pregnancy in Diabetics', 'Prevalence'] | 7,969,000 | [['M01.060.116'], ['E05.318.308.940.250', 'L01.399.250.900.250', 'N04.452.859.132', 'N05.715.360.300.715.175', 'N06.850.520.308.940.250'], ['C13.703.170', 'C18.452.394.750.448', 'C19.246.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.560', 'N05.715.350.075.550', 'N06.850.490.250.550'], ['Z01.107.567.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
The CCC2000 Birth Cohort Study of Register-Based Family History of Mental Disorders and Psychotic Experiences in Offspring. | Psychotic experiences (PE) in individuals of the general population are hypothesized to mark the early expression of the pathology underlying psychosis. This notion of PE as an intermediate phenotype is based on the premise that PE share genetic liability with psychosis. We examined whether PE in childhood was predicte... | ['Child', 'Delusions', 'Denmark', 'Female', 'Hallucinations', 'Humans', 'Male', 'Pedigree', 'Psychotic Disorders', 'Registries', 'Risk', 'Schizophrenia'] | 25,452,427 | [['M01.060.406'], ['F01.145.126.200'], ['Z01.542.816.124'], ['C10.597.606.762.300', 'C23.888.592.604.764.300', 'F01.700.750.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.673'], ['F03.700.675'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300.715.700', 'N06.850.520.308.970'], ['E05.318.740.60... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Chimerism after vascularized limb versus bone marrow transplantation. | This study used quantitative PCR in the murine model to compare the ability of a limb allograft vs. a comparable dose of marrow suspension to induce chimerism. Female C57Bl/6 mice received a vascularized hindlimb allograft, a comparable dose of 5 x 10 (6) donor bone marrow cells, or a standard dose (20 x 10 (6)) of mar... | ['Animals', 'Bone Marrow Transplantation', 'CD40 Ligand', 'Chimerism', 'Female', 'Hindlimb', 'Immune Tolerance', 'Lymphocyte Depletion', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Models, Animal', 'Polymerase Chain Reaction', 'Random Allocation', 'Transplantation, Homologous'] | 16,845,620 | [['B01.050'], ['E02.095.147.725.040', 'E04.936.580.040'], ['D12.644.276.374.750.124', 'D12.776.395.550.185', 'D12.776.467.374.750.124', 'D12.776.543.550.198', 'D23.529.374.750.124'], ['G05.365.590.175.125'], ['A13.473'], ['G12.535.425'], ['E02.095.465.425.450.521', 'E05.478.610.570'], ['B01.050.150.900.649.313.992.635.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Empirical approaches to epidemiology of the Middle Ages]. | Diseases result from hazards and influences originating in one's environment and could be described in evolutionary terms as maladaptations. Variations in the pattern of diseases throughout times and places can therefore indicate variations in the living conditions of ancient populations. Palaeopathology is the only wa... | ['Germany', 'History, Medieval', 'Humans', 'Osteomyelitis', 'Paleopathology', 'Periostitis', 'Spondylitis, Ankylosing', 'Tuberculosis, Osteoarticular'] | 1,292,151 | [['Z01.542.315'], ['K01.400.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.160.495', 'C05.116.165.495'], ['I01.076.368.584.709'], ['C01.160.595', 'C05.116.165.595'], ['C05.116.900.853.625.800.850', 'C05.550.069.680', 'C05.550.114.865.800.850'], ['C01.150.252.410.040.552.846.843', 'C01.160.886', 'C05.116.... | ['Geographicals [Z]', 'Humanities [K]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
The diagnosis of dementia in the elderly. A comparison of CAMCOG (the cognitive section of CAMDEX), the AGECAT program, DSM-III, the Mini-Mental State Examination and some short rating scales. | The performance of CAMCOG, the cognitive section of the CAMDEX, is compared in a non-random sample of 222 elderly people with diagnoses based on AGECAT and on DSM-III criteria, and with the MMSE and some short rating scales. With a cut-off point of 69/70 and AGECAT organic syndrome as the criterion, the sensitivity of ... | ['Aged', 'Aged, 80 and over', 'Dementia', 'Depressive Disorder', 'Female', 'Humans', 'Male', 'Mental Status Schedule', 'Middle Aged', 'Neuropsychological Tests', 'Psychiatric Status Rating Scales', 'Psychometrics', 'Social Environment'] | 1,773,235 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380', 'F03.615.400'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513.603.500', 'F04.711.513.653.574'], ['M01.060.116.630'], ['F04.711.513'], ['F04.711.513.653'], ['F04.711.780'], ['I01.880.853.500']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Accumulation of albumin-linked and free-form pentosidine in the circulation of uremic patients with end-stage renal failure: renal implications in the pathophysiology of pentosidine. | Pentosidine is an advanced glycation end product and its formation is shown to be closely related to oxidative processes. Recent studies have shown that pentosidine levels are increased not only in plasma and matrix proteins from diabetic patients, but also markedly in nondiabetic hemodialysis patients. Currently, the ... | ['Animals', 'Arginine', 'Creatinine', 'Diabetes Mellitus, Type 2', 'Diabetic Nephropathies', 'Diet', 'Glomerulonephritis', 'Humans', 'Kidney Failure, Chronic', 'Lysine', 'Maillard Reaction', 'Nephrectomy', 'Oxidation-Reduction', 'Protein Binding', 'Rats', 'Rats, Wistar', 'Serum Albumin', 'Uremia', 'beta 2-Microglobulin... | 8,866,413 | [['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D03.383.129.308.207'], ['C18.452.394.750.149', 'C19.246.300'], ['C12.777.419.192', 'C13.351.968.419.192', 'C19.246.099.875'], ['G07.203.650.240'], ['C12.777.419.570.363', 'C13.351.968.419.570.363'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Online literature searches--a new dimension in mastering the information avalanche? A demonstration using examples]. | Several examples of online literature searches in the Chemical Abstracts, Science Citation Index, and Biological Abstracts data bases are discussed to demonstrate that online searching is a powerful and very useful tool for retrieving information faster and more efficiently than before. This article attempts to stimula... | ['Animals', 'Biology', 'Chemical Phenomena', 'Chemistry', 'Chromatography, High Pressure Liquid', 'Humans', 'Online Systems', 'Porphyrins', 'Research'] | 7,110,361 | [['B01.050'], ['H01.158.273'], ['G02'], ['H01.181'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500.750.300.742'], ['D03.383.129.578.840.500', 'D03.633.400.909.500', 'D04.345.783.500', 'D23.767.727'], ['H01.770.644']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[Exploration on the relationship between pathogenesis for yin-deficiency of acute myocardial infarction and immediate prognosis as well as its mechanism]. | OBJECTIVE: To study the relationship between pathogenesis for Yin-deficiency of acute myocardial infarction (AMI) and immediate prognosis as well as its neuro-endocrine mechanism.METHODS: According to the TCM standard of Syndrome Differentiation of Deficiency Syndrome, 194 patients with AMI were classified into the typ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Creatine Kinase', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Medicine, Chinese Traditional', 'Middle Aged', 'Myocardial Infarction', 'Prognosis', 'Yin Deficiency'] | 15,199,621 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.913.696.640.150'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Global gene expression analysis reveals differences in cellular responses to hydroxyl- and superoxide anion radical-induced oxidative stress in caco-2 cells. | Reactive oxygen species-induced oxidative stress in the colon is involved in inflammatory bowel diseases and suggested to be associated with colorectal cancer risk. However, our insight in molecular responses to different oxygen radicals is still fragmentary. Therefore, we studied global gene expression by an extensive... | ["8-Hydroxy-2'-Deoxyguanosine", 'Adenocarcinoma', 'Antineoplastic Agents', 'Apoptosis', 'Caco-2 Cells', 'Cell Cycle', 'Colonic Neoplasms', 'Deoxyguanosine', 'Electron Spin Resonance Spectroscopy', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Hydrogen Peroxide', 'Microarray Analysis'... | 20,044,591 | [['D03.633.100.759.590.454.240.500', 'D13.570.230.360.500', 'D13.570.583.454.240.500'], ['C04.557.470.200.025'], ['D27.505.954.248'], ['G04.146.954.035'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['G04.144'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C0... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Full elucidation of the transmembrane anion transport mechanism of squaramides using in silico investigations. | A comprehensive experimental and theoretical investigation of the transmembrane chloride transport promoted by four series of squaramide derivatives, with different degrees of fluorination, number of convergent N-H binding units and conformational shapes, is reported. The experimental chloride binding and transport abi... | ['Anions', 'Computer Simulation', 'Diffusion', 'Hydrogen Bonding', 'Ion Transport', 'Liposomes', 'Molecular Conformation', 'Molecular Dynamics Simulation', 'Phospholipids', 'Quantum Theory', 'Quinine', 'Thermodynamics', 'Water'] | 29,978,159 | [['D01.248.497.158'], ['L01.224.160'], ['G01.202', 'G02.196'], ['G02.282'], ['G03.143.500'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['G02.111.570.820'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D10.570.755'], ['H01.671.579.800'], ['D03.132.206.719', 'D03.60... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
What do zebrafish want? Impact of social grouping, dominance and gender on preference for enrichment. | Although environmental enrichment is known to improve laboratory rodent wellbeing and enhance scientific data collection, relatively little is known with regards to the type of enrichment that might be useful for zebrafish (Danio rerio). Therefore, this study explored if zebrafish displayed preferences for a range of e... | ['Animal Husbandry', 'Animals', 'Dominance-Subordination', 'Environment', 'Female', 'Male', 'Sex Factors', 'Social Behavior', 'Zebrafish'] | 24,939,904 | [['J01.040.090'], ['B01.050'], ['F01.145.813.650.400'], ['G16.500.275', 'N06.230'], ['N05.715.350.675', 'N06.850.490.875'], ['F01.145.813'], ['B01.050.150.900.493.200.244.828']] | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The Clinical Value of N-Terminal Pro B-Type Natriuretic Peptide in Evaluating Obstructive Sleep Apnea in Patients With Coronary Artery Disease. | STUDY OBJECTIVES: Natriuretic peptides have been identified as biomarkers of increased myocardial wall stress in the context of obstructive sleep apnea (OSA) in the general population. However, the relationship between N-terminal pro B-type natriuretic peptide (NT-proBNP) and OSA remains unclear in patients with corona... | ['Biomarkers', 'China', 'Coronary Artery Disease', 'Female', 'Humans', 'Male', 'Middle Aged', 'Natriuretic Peptide, Brain', 'Peptide Fragments', 'Prospective Studies', 'Sleep Apnea, Obstructive'] | 31,596,204 | [['D23.101'], ['Z01.252.474.164'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D06.472.699.584.625', 'D12.644.548.585.625', 'D12.776.631.590'], ['D12.644.541'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', '... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
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