Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Analysis of Factors Influencing Inpatient and Outpatient Satisfaction with the Chinese Military Health Service. | BACKGROUND: Relatively few articles have focused on exploring factors influencing soldiers' overall satisfaction and differences between inpatients' and outpatients' satisfaction, particularly in the Chinese army. Elucidating factors influencing military inpatient and outpatient care separately and analyzing their diff... | ['Adolescent', 'Adult', 'China', 'Humans', 'Inpatients', 'Military Medicine', 'Outpatients', 'Patient Satisfaction'] | 27,007,805 | [['M01.060.057'], ['M01.060.116'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['H02.403.500'], ['M01.643.630'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600']] | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
A phase II survival comparison of patients with adenocarcinoma of the pancreas treated with 5-fluorouracil and calcium leucovorin versus a matched tumor registry control population. | Carcinoma of the pancreas is a virulent malignancy. We performed a Phase II survival study by treating 30 patients with pancreatic cancer with leucovorin, 200 mg/m2 x 5 days immediately followed by 5-fluorouracil, 370 mg/m2 every 4 weeks. We examined the survival of our 30 study patients with patients drawn from the Ma... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Fluorouracil', 'Humans', 'Leucovorin', 'Male', 'Middle Aged', 'Pancreatic Neoplasms', 'Registries', 'Remission Induction', 'Survival Analysis'] | 7,977,161 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.733.631.400.800.350.450', 'D08.211.840.300.500'], ['M01.060.116.630'], ['C04.588.274.761', 'C04.588.322.475', 'C06.301.761', 'C06.689.667',... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Representations of numerical and non-numerical magnitude both contribute to mathematical competence in children. | A growing body of evidence suggests that non-symbolic representations of number, which humans share with nonhuman animals, are functionally related to uniquely human mathematical thought. Other research suggesting that numerical and non-numerical magnitudes not only share analog format but also form part of a general m... | ['Child', 'Child Development', 'Child, Preschool', 'Comprehension', 'Female', 'Humans', 'Male', 'Mathematics', 'Mental Competency', 'Symbolism'] | 27,146,696 | [['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['F02.463.188.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.548'], ['F01.590', 'F02.410', 'I01.880.604.583.530', 'N03.706.535.625'], ['K01.400.899', 'K01.752.798']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Pseudomalignant myositis ossificans. A pathological study of eight cases. | Eight cases of pseudomalignant myositis ossificans are presented. There was a male predominance and four patients were under 20 years of age. There was no history of trauma, but there was evidence of mild local or general inflammation with positive roentgenograms in two cases. Histologically there was active fibroblast... | ['Adolescent', 'Adult', 'Bone Matrix', 'Bone and Bones', 'Child', 'Connective Tissue', 'Diagnosis, Differential', 'Female', 'Humans', 'Hyperplasia', 'Male', 'Middle Aged', 'Muscles', 'Myositis Ossificans', 'Soft Tissue Neoplasms'] | 1,183,991 | [['M01.060.057'], ['M01.060.116'], ['A10.165.265.166'], ['A02.835.232', 'A10.165.265'], ['M01.060.406'], ['A10.165'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['M01.060.116.630'], ['A02.633', 'A10.690'], ['C05.651.594.638'], ['C04.588.839']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Subgingival Microbial Changes During the First 3 Months of Fixed Appliance Treatment in Female Adult Patients. | Although periodontal diseases during fixed appliance treatment are a common issue, few studies have focused on the clinical and microbial factors associated with orthodontic appliances. Hence, we investigated changes in the subgingival microbial community and their association with periodontal changes at the early stag... | ['Adult', 'Bacteria', 'Bacterial Load', 'Dental Plaque Index', 'Female', 'Gingiva', 'Hemorrhage', 'Humans', 'Inflammation', 'Microbiota', 'Orthodontic Appliances, Fixed', 'Periodontal Diseases', 'Porphyromonas gingivalis', 'Prevotella intermedia', 'RNA, Ribosomal, 16S', 'Time Factors', 'Young Adult'] | 30,542,916 | [['M01.060.116'], ['B03'], ['E01.370.225.875.150.115', 'E01.370.225.875.220.115', 'E05.200.875.150.115', 'E05.200.875.220.115', 'G06.099.100'], ['E05.318.308.980.438.300.300', 'E06.208.250', 'N05.715.360.300.800.438.300.325', 'N06.850.520.308.980.438.300.300', 'N06.890.160.090'], ['A14.549.167.646.480'], ['C23.550.414'... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A Hybrid Nanomaterial for the Controlled Generation of Free Radicals and Oxidative Destruction of Hypoxic Cancer Cells. | Anticancer modalities based on oxygen free radicals, including photodynamic therapy and radiotherapy, have emerged as promising treatments in the clinic. However, the hypoxic environment in tumor tissue prevents the formation of oxygen free radicals. Here we introduce a novel strategy that employs oxygen-independent fr... | ['A549 Cells', 'Antineoplastic Agents', 'Apoptosis', 'Cell Proliferation', 'Cell Survival', 'Drug Screening Assays, Antitumor', 'Free Radicals', 'Gold', 'Humans', 'Hypoxia', 'Metal Nanoparticles', 'Neoplasms', 'Oxidation-Reduction', 'Oxygen', 'Particle Size', 'Photochemotherapy', 'Photosensitizing Agents', 'Surface Pro... | 28,464,414 | [['A11.251.210.190.080', 'A11.251.860.180.080', 'A11.436.054'], ['D27.505.954.248'], ['G04.146.954.035'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['D01.339', 'D02.389'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Splicing mutations in DMD/BMD detected by RT-PCR/PTT: detection of a 19AA insertion in the cysteine rich domain of dystrophin compatible with BMD. | We have used an RNA based mutation detection method to screen the total coding region of the dystrophin gene of a Duchenne and a Becker muscular dystrophy patient in whom DNA based mutation detection methods have so far failed to detect mutations. By RT-PCR and the protein truncation test (PTT) we could identify point ... | ['Adolescent', 'Amino Acid Sequence', 'Base Sequence', 'Blotting, Western', 'Cell Differentiation', 'Child', 'Cysteine', 'DNA Transposable Elements', 'Dystrophin', 'Female', 'Fibroblasts', 'Heterozygote', 'Humans', 'Male', 'Molecular Sequence Data', 'Muscular Dystrophies', 'Mutation', 'MyoD Protein', 'Pedigree', 'Polym... | 8,950,674 | [['M01.060.057'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.152'], ['M01.060.406'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.1... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Adsorption of cyanine dyes on gold nanoparticles and formation of J-aggregates in the nanoparticle assembly. | This paper describes the results of an investigation of the interparticle interactions and reactivities in the assembly of gold nanoparticles mediated by cyanine dyes. The combination of the positively charged indolenine cyanine dyes and the negatively charged gold nanoparticles is shown to form a J-aggregate bridged a... | ['Adsorption', 'Carbocyanines', 'Gold', 'Metal Nanoparticles', 'Microscopy, Electron, Transmission', 'Molecular Structure', 'Spectrophotometry', 'Static Electricity'] | 16,570,972 | [['G01.030', 'G02.020'], ['D02.455.326.397.300'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['J01.637.512.600.500'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['G02.111.570', 'G02.466'], ['E05.196.712.726', 'E05.196.867.826'], ['G01.358.500.249.820']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Can tissue transglutaminase be a marker of idiopathic inflammatory myopathies? | In the normal striated muscle, tissue transglutaminase (TG2) content is vestigial. However, this protein's presence has been reported to occur in myoblasts and myotubes during the fetal period. Its increased expression has been also found in the muscle tissue in the course of sporadic inclusion body myositis, as well a... | ['Animals', 'Biomarkers', 'Dermatomyositis', 'GTP-Binding Proteins', 'Guinea Pigs', 'Humans', 'Inflammation', 'Male', 'Polymyositis', 'Transglutaminases'] | 15,752,564 | [['B01.050'], ['D23.101'], ['C05.651.594.819.500', 'C10.668.491.562.575.500', 'C17.300.250', 'C17.800.185'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['C05.651.594.819', 'C10.668.491.562.575'], ['D08.811.913.05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bacilysin overproduction in Bacillus amyloliquefaciens FZB42 markerless derivative strains FZBREP and FZBSPA enhances antibacterial activity. | Bacillus amyloliquefaciens strains FZBREP and FZBSPA were derived from the wild-type FZB42 by replacement of the native bacilysin operon promoter with constitutive promoters P repB and P spac from plasmids pMK3 and pLOSS, respectively. These strains contained two antibiotic resistance genes, and markerless strains were... | ['Actinobacteria', 'Anti-Bacterial Agents', 'Antibiosis', 'Bacillus', 'Dipeptides', 'Genetic Engineering', 'Operon', 'Plant Diseases', 'Solanum tuberosum', 'Staphylococcus aureus'] | 25,472,439 | [['B03.510.024', 'B03.510.460.400.400.049'], ['D27.505.954.122.085'], ['G06.550.050', 'G16.062'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['D12.644.456.345'], ['E05.393.420'], ['G05.360.340.024.686', 'G05.360.340.358.207.500'], ['G... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of elevated CO₂ on tobacco caterpillar, Spodoptera litura on peanut, Arachis hypogea. | If the carbon dioxide (CO(2)) concentration in the atmosphere changes in the future, as predicted, it could influence crops and insect pests. The growth and development of the tobacco caterpillar, Spodoptera litura (Fabricius) (Noctuidae: Lepidoptera), reared on peanut (Arachis hypogea L.) foliage grown under elevated ... | ['Analysis of Variance', 'Animals', 'Arachis', 'Carbon Dioxide', 'Herbivory', 'India', 'Insect Control', 'Larva', 'Plant Leaves', 'Spectrophotometry', 'Spodoptera'] | 23,437,971 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['B01.650.940.800.575.912.250.401.077'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['F01.145.113.547.600', 'F01.145.407.758', 'G07.203.650.353.758'], ['Z01.252.245.393'], ['N06.850.780.200.650.425'], ['B05.500.500', 'G07.345.500.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[The effect of oxytocin and vasopressin on individual behavior and EEG-correlates of narcotic dependent rats in the "open field" test]. | A single intracerebral injection of oxytocin activated the behavior, increased the frequency and amount of hippocampal theta-rhythm whereas vasopressin elicited opposite effects during "open field" test in drug-dependent rats with implanted electrodes in different brain structures. | ['Animals', 'Behavior, Animal', 'Electroencephalography', 'Heroin', 'Hippocampus', 'Male', 'Opioid-Related Disorders', 'Oxytocin', 'Rats', 'Rats, Inbred Strains', 'Vasopressins'] | 2,759,279 | [['B01.050'], ['F01.145.113'], ['E01.370.376.300', 'E01.370.405.245'], ['D03.132.577.249.562.445', 'D03.605.497.607.490', 'D03.633.400.686.607.490', 'D04.615.723.795.576.445'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['C25.775.643.500', 'F03.900.647.500'], ['D06.472.699.631.692.433', 'D12.644.548.69... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of endotoxin release and cytokine production induced by antibiotics in patients with Gram-negative nosocomial pneumonia. | OBJECTIVE: To determine the plasma concentrations of lipopolysaccharide, tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 in a homogeneous group of septic patients and to evaluate the effect of antibiotic treatment, imipenem or ceftazidime, on the release of lipopolysaccharide and cytokines.DESIGN: Pr... | ['Anti-Bacterial Agents', 'Ceftazidime', 'Cephalosporins', 'Cross Infection', 'Cytokines', 'Female', 'Gram-Negative Bacterial Infections', 'Humans', 'Imipenem', 'Interleukin-1', 'Interleukin-6', 'Lipopolysaccharides', 'Male', 'Middle Aged', 'Pneumonia, Bacterial', 'Prospective Studies', 'Sepsis', 'Statistics, Nonparame... | 11,889,308 | [['D27.505.954.122.085'], ['D02.065.589.099.249.210.150', 'D02.886.665.074.210.150', 'D03.633.100.300.249.210.150'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['C01.248', 'C23.550.291.875.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C01.150.252.400'], ['B01.050.150.900.649.31... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Temporal dynamics of methyltransferase and restriction endonuclease accumulation in individual cells after introducing a restriction-modification system. | Type II restriction-modification (R-M) systems encode a restriction endonuclease that cleaves DNA at specific sites, and a methyltransferase that modifies same sites protecting them from restriction endonuclease cleavage. Type II R-M systems benefit bacteria by protecting them from bacteriophages. Many type II R-M syst... | ['DNA Modification Methylases', 'DNA Restriction-Modification Enzymes', 'Deoxyribonuclease BamHI', 'Escherichia coli', 'Luminescent Proteins', 'Microscopy, Fluorescence', 'Models, Biological', 'Recombinant Proteins', 'Single-Cell Analysis'] | 26,687,717 | [['D08.811.150.240', 'D08.811.913.555.500.350'], ['D08.811.150'], ['D08.811.150.280.260.240', 'D08.811.277.352.335.350.300.260.240', 'D08.811.277.352.355.325.300.260.240'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.532'], ['E01.370.350.515.458', 'E05.595.458'], ['E05.599.395'], ['D12.776.828'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid generation of sequence variation during primary HIV-1 infection. | OBJECTIVE: HIV-1 undergoes extensive genetic variation in infected individuals. The extent of genetic variation has been examined in patients with AIDS, but little is known regarding the appearance of HIV-1 genetic variation immediately following infection during the primary phase of HIV-1 infection prior to seroconver... | ['Adult', 'Amino Acid Sequence', 'Base Sequence', 'Blotting, Western', 'Genetic Variation', 'HIV Infections', 'HIV-1', 'Humans', 'Male', 'Molecular Sequence Data', 'Mutation', 'Sequence Homology, Nucleic Acid'] | 1,616,650 | [['M01.060.116'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G05.365'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.40... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Tributyltin exposure results in craniofacial cartilage defects in rockfish (Sebastiscus marmoratus) embryos. | Tributyltin (TBT) is a ubiquitous marine environmental contaminant, which has been known to cause axial skeletal deformities in fish embryos. However, the effects of TBT on the craniofacial cartilage development of fishes remain unclear. The present study was designed to investigate the effects of waterborne TBT at env... | ['Alcian Blue', 'Analysis of Variance', 'Animals', 'Calcium', 'Cartilage', 'Chondrocytes', 'Craniofacial Abnormalities', 'DNA Primers', 'Dose-Response Relationship, Drug', 'Embryo, Nonmammalian', 'Fishes', 'Hedgehog Proteins', 'Proliferating Cell Nuclear Antigen', 'Real-Time Polymerase Chain Reaction', 'Receptors, Reti... | 22,261,028 | [['D03.633.100.473.050'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A02.165', 'A10.165.382'], ['A11.329.171'], ['C05.660.207', 'C16.131.621.207'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G07.690.773.875'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Structural basis for hydration dynamics in radical stabilization of bilin reductase mutants. | Heme-derived linear tetrapyrroles (phytobilins) in phycobiliproteins and phytochromes perform critical light-harvesting and light-sensing roles in oxygenic photosynthetic organisms. A key enzyme in their biogenesis, phycocyanobilin:ferredoxin oxidoreductase (PcyA), catalyzes the overall four-electron reduction of biliv... | ['Asparagine', 'Bacterial Proteins', 'Bile Pigments', 'Catalysis', 'Catalytic Domain', 'Crystallography, X-Ray', 'Histidine', 'Mutation', 'Oxidoreductases', 'Phycobilins', 'Phycocyanin', 'Protein Conformation', 'Water'] | 20,557,110 | [['D12.125.068.060', 'D12.125.095.165', 'D12.125.154.049'], ['D12.776.097'], ['D03.383.129.578.840.249', 'D03.633.400.909.249', 'D04.345.783.249', 'D23.767.193'], ['G02.130'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.196.309.742.225'], ['D12.125.072.329', 'D12.125.142.308'], ['G05.365.590'], ['... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficiency of recombinant thymosin â4 in spontaneous mouse model of chronic dermatitis. | The therapeutic efficiency of recombinant thymosin â4 (rTâ4) synthesized by us was studied in vivo on spontaneous CBRB mouse model that is adequate to human chronic dermatitis. Three applications of the drug during a week significantly alleviated symptoms of the disease in female mice, and in complex with subsequent an... | ['Animals', 'Chronic Disease', 'Dermatitis', 'Disease Models, Animal', 'Female', 'Mice', 'Recombinant Proteins', 'Thymosin'] | 25,778,656 | [['B01.050'], ['C23.550.291.500'], ['C17.800.174'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.828'], ['D06.472.910.850', 'D12.644.548.869', 'D12.776.922']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Laurell electroimmunodiffusion. Concerns and limits of various technics for the study of immunoaffinity chromatographic eluants]. | Monodimensional and bidimensional electroimmunodifusion techniques were applied to the study of immunochromatography eluates. They were obtained with human sera as samples, and rabbit anti human sera alpha1AGP antibodies coupled to CNBr Sepharose 4B packed in a chromatography column. By monodimensional electroimmunodif... | ['Antibodies', 'Chromatography, Affinity', 'Humans', 'Immunoelectrophoresis', 'Orosomucoid'] | 908,128 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E05.196.181.400.170'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.735.645.350.350', 'E05.196.401.568', 'E05.200.812.735.645.350.350', 'E05.301.300.568', 'E05.478.594.760.645.350.350', 'E05.478.605.492.350.350']... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of responses to serotonin in the pulmonary vascular bed of the cat. | Pulmonary vascular responses to serotonin (5-hydroxytryptamine; 5-HT) were investigated in the intact-chest cat under constant-flow conditions. Injections of 5-HT into the perfused lobar artery in doses of 1-30 micrograms caused dose-related increases in lobar arterial pressure and, at doses of 3-30 micrograms, decreas... | ['15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid', 'Adrenergic alpha-Antagonists', 'Animals', 'Arginine', 'Blood Pressure', 'Bronchi', 'Cats', 'Female', 'Fluoxetine', 'In Vitro Techniques', 'Ketanserin', 'Male', 'Meclofenamic Acid', 'Muscle Tonus', 'NG-Nitroarginine Methyl Ester', 'Norepinephrine', ... | 8,104,177 | [['D01.248.497.158.685.750.744.650.500.500', 'D01.339.431.374.744.650.500.500', 'D01.650.550.750.700.650.500.500', 'D02.389.338.638.650.500.500', 'D10.251.355.255.550.025.650.500.500', 'D23.469.050.175.725.025.650.500.500', 'D23.469.700.630.500'], ['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['B01.05... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of Corneal Thickness on the Penetration of Topical Vancomycin. | PURPOSE: To study the influence of corneal thickness on intraocular penetration of topical ophthalmic drops, using vancomycin 50 mg/mL drops as a model.METHODS: The study included 58 eyes of 58 patients undergoing phacoemulsification cataract extraction. The central corneal thickness was measured by ultrasonic pachymet... | ['Administration, Topical', 'Adult', 'Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Aqueous Humor', 'Cornea', 'Corneal Pachymetry', 'Female', 'Humans', 'Male', 'Middle Aged', 'Ophthalmic Solutions', 'Phacoemulsification', 'Vancomycin'] | 26,258,280 | [['E02.319.267.120'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['A09.371.060.067.070', 'A12.207.270.040'], ['A09.371.060.217'], ['E01.370.380.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D26.776.708.645', 'D27.505.954.578.645', 'D27.720.75... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Homologies between T cell receptor junctional sequences unique to multiple sclerosis and T cells mediating experimental allergic encephalomyelitis. | The selection of T cell clones with mutations in the hypoxanthine guanine phosphoribosyltransferase (hprt) gene has been used to isolate T cells reactive to myelin basic protein (MBP) in patients with multiple sclerosis (MS). These T cell clones are activated in vivo, and are not found in healthy individuals. The third... | ['Amino Acid Sequence', 'Base Sequence', 'Encephalomyelitis, Autoimmune, Experimental', 'Humans', 'Hypoxanthine Phosphoribosyltransferase', 'Molecular Sequence Data', 'Multiple Sclerosis', 'Polymerase Chain Reaction', 'Receptors, Antigen, T-Cell, alpha-beta', 'Sequence Homology, Amino Acid', 'T-Lymphocytes'] | 8,040,252 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.314.350.250', 'C20.111.258.625.300', 'E05.598.500.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.400.725.450'], ['L01.453.245.667'], ['C1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Novel Insights in the Regulation of Phosphatidylserine Exposure in Human Red Blood Cells. | BACKGROUND/AIMS: In previous publications we were able to demonstrate the exposure of phosphatidylserine (PS) in the outer membrane leaflet after activation of red blood cells (RBCs) by lysophosphatidic acid (LPA), phorbol-12 myristate-13acetate (PMA), or 4-bromo-A23187 (A23187). It has been concluded that three differ... | ['Annexin A5', 'Benzophenanthridines', 'Calcimycin', 'Calcium', 'Cells, Cultured', 'Charybdotoxin', 'Erythrocyte Count', 'Erythrocytes', 'Gene Expression Regulation', 'Humans', 'Intermediate-Conductance Calcium-Activated Potassium Channels', 'Lysophospholipids', 'Methomyl', 'Naphthalenes', 'Phosphatidylserines', 'Phosp... | 27,771,709 | [['D12.776.157.125.050.100'], ['D03.132.089', 'D03.633.300.633.207', 'D03.633.400.131'], ['D03.633.100.221.173'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251'], ['D12.644.115', 'D20.888.065.830.150', 'D23.946.833.065.830.150'], ['E01.370.225.500.195.107.330', 'E01.370.225.625.107.330', 'E05.200.500... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Myomectomy during cesarean section: a safe procedure? | A patient's frequent request is the simultaneous surgical removal of a previously diagnosed myoma during cesarean section. The aim of this study was to evaluate the safety and efficacy of myomectomy during cesarean section. From January 1995 until December 2004, 47 pregnant women with coexisting uterine myomas underwen... | ['Adult', 'Case-Control Studies', 'Cesarean Section', 'Female', 'Greece', 'Humans', 'Leiomyoma', 'Outcome Assessment, Health Care', 'Postoperative Complications', 'Pregnancy', 'Pregnancy Complications, Neoplastic', 'Risk Assessment', 'Safety', 'Treatment Outcome', 'Uterine Neoplasms'] | 17,308,166 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E04.520.252.500'], ['Z01.542.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.590.450'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['C23.550.767'], ['G08.686.784.769'], ['C04.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Stillbirth (co)variance components for a sire-maternal grandsire threshold model and development of a calving ability index for sire selection. | (Co)variance components for stillbirth in US Holsteins were estimated under a sire-maternal grandsire threshold model using subsets of data from the national calving ease database, which includes over 6 million calving records with associated stillbirth scores. Stillbirth was coded as a binomial trait indicating whethe... | ['Animals', 'Bayes Theorem', 'Breeding', 'Cattle', 'Dairying', 'Female', 'Heredity', 'Male', 'Models, Genetic', 'Parity', 'Parturition', 'Pregnancy', 'Selection, Genetic', 'Stillbirth'] | 17,430,953 | [['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['E05.820.150', 'G05.090'], ['B01.050.150.900.649.313.500.380.271'], ['J01.040.246'], ['G05.390'], ['E05.599.395.397'], ['G08.686.677', 'G08.686.784.769.472', 'N06.850.490.812.600'], ['G08.686.784.769.490'], ['G08.686.784.769']... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
A high spectral efficiency optical OFDM scheme based on interleaved multiplexing. | By multiplexing two OFDM signals with the same channel space and bit rate together in an interleaved mode, a novel optical multiplexing scheme is proposed and experimentally demonstrated. Since the channel space is halved, the spectral efficiency is doubled compared with conventional OFDM. It is proved that the orthogo... | ['Computer-Aided Design', 'Equipment Design', 'Equipment Failure Analysis', 'Optical Devices', 'Refractometry', 'Signal Processing, Computer-Assisted', 'Telecommunications'] | 21,164,963 | [['L01.224.108.150', 'L01.296.110.150'], ['E05.320'], ['E05.325.192'], ['E07.632'], ['E05.196.808', 'H01.671.617.755'], ['L01.224.800'], ['L01.178.847']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Blunted inhibition by insulin of agonist-stimulated calcium, pH and aggregatory responses in platelets from hypertensive patients. | INTRODUCTION: Insulin may influence platelet function by modulating platelet responsiveness to vasoactive agonists. In essential hypertension platelet hyperactivity might be related to altered modulation by insulin. The present study examined the effects of physiological concentrations of insulin on agonist-stimulated ... | ['Adult', 'Angiotensin II', 'Blood Platelets', 'Blood Pressure', 'Calcium', 'Case-Control Studies', 'Cytosol', 'Endothelins', 'Female', 'Humans', 'Hydrogen-Ion Concentration', 'Hypertension', 'Insulin', 'Intracellular Fluid', 'Male', 'Middle Aged', 'Platelet Aggregation', 'Spectrometry, Fluorescence', 'Thrombin'] | 7,868,873 | [['M01.060.116'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['A11.118.188', 'A15.145.229.188'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.318.372.500.500',... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The estrogen receptor: a structure-based approach to the design of new specific hormone-receptor combinations. | BACKGROUND: The specificity of hormone action arises from complementary steric and electronic interactions between a hormonal ligand and its cognate receptor. An analysis of such key ligand-receptor contact sites, often delineated by mutational mapping and X-ray crystallographic studies, can suggest ways in which hormo... | ['Animals', 'Binding Sites', 'Dose-Response Relationship, Drug', 'Drug Design', 'Estrogens', 'Humans', 'Ligands', 'Models, Molecular', 'Molecular Structure', 'Mutagenesis, Site-Directed', 'Protein Binding', 'Receptors, Estrogen', 'Structure-Activity Relationship', 'Substrate Specificity'] | 11,306,352 | [['B01.050'], ['G02.111.570.120'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['D27.505.696.399.472.277'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.480'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['E05.393.420.601.575'], ['G02.111... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Vitamin D supplementation in the management of knee osteoarthritis: study protocol for a randomized controlled trial. | BACKGROUND: Osteoarthritis (OA) is a common health issue worldwide in the aging population who are also commonly deficient in vitamin D. Our previous study suggested that higher serum 25-(OH)D levels were associated with reduced knee cartilage loss, implying that vitamin D supplementation may prevent the progression of... | ['Arthralgia', 'Bone Density Conservation Agents', 'Disease Progression', 'Double-Blind Method', 'Humans', 'Magnetic Resonance Imaging', 'Muscle Strength', 'Osteoarthritis, Knee', 'Placebos', 'Research Design', 'Tasmania', 'Treatment Outcome', 'Victoria', 'Vitamin D', 'Vitamin D Deficiency', 'Vitamins'] | 22,867,111 | [['C05.550.091', 'C23.888.592.612.094', 'F02.830.816.444.350', 'G11.561.790.444.350'], ['D27.505.696.242'], ['C23.550.291.656'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E01.370.600.425', 'G11.427.56... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Superior vena cava syndrome in a patient with locally advanced lung cancer with good response to definitive chemoradiation: a case report. | BACKGROUND: The incidence of superior vena cava syndrome within the United States is roughly 15,000 cases per year. Superior vena cava syndrome is a potentially life-threatening medical condition; however, superior vena cava syndrome is not fatal in the majority of cases. Superior vena cava syndrome encompasses a colle... | ['Carcinoma, Non-Small-Cell Lung', 'Chemoradiotherapy', 'Female', 'Humans', 'Lung Neoplasms', 'Middle Aged', 'Superior Vena Cava Syndrome', 'Tomography, X-Ray Computed', 'Vena Cava, Superior'] | 30,340,621 | [['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E02.186.079', 'E02.319.164', 'E02.815.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['C14.907.800'], ['E01.370.350.350.810', 'E01.370.350.600.35... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neutralization of the aspartic acid residue Asp-367, but not Asp-454, inhibits binding of Na+ to the glutamate-free form and cycling of the glutamate transporter EAAC1. | Substrate transport by the plasma membrane glutamate transporter EAAC1 is coupled to cotransport of three sodium ions. One of these Na(+) ions binds to the transporter already in the absence of glutamate. Here, we have investigated the possible involvement of two conserved aspartic acid residues in transmembrane segmen... | ['Amino Acid Sequence', 'Amino Acid Transport System X-AG', 'Animals', 'Anions', 'Aspartic Acid', 'Binding Sites', 'Binding, Competitive', 'Biological Transport', 'Catalysis', 'Cell Line', 'Cell Membrane', 'Cloning, Molecular', 'Dose-Response Relationship, Drug', 'Electrophysiology', 'Excitatory Amino Acid Transporter ... | 16,478,724 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.157.530.200.249.500', 'D12.776.157.530.937.250', 'D12.776.543.585.200.249.500', 'D12.776.543.585.937.250'], ['B01.050'], ['D01.248.497.158'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['G02.111.570.120'], ['E05.196.080', 'G02.111.084', 'G02.111.570... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Targeted deletion of caspase-1 reduces early mortality and left ventricular dilatation following myocardial infarction. | Objective. - Mice with targeted deletion of caspase-1 (interleukin-1beta (IL-1beta)-converting enzyme) lack the active forms of IL-1beta and IL-18, two cytokines implicated in maladaptive ventricular remodeling following cardiac injury. We, therefore, investigated the extent of ventricular dilation in caspase-1-knockou... | ['Animals', 'Apoptosis', 'Bisbenzimidazole', 'Blotting, Northern', 'Blotting, Western', 'Caspase 1', 'Collagen', 'Coloring Agents', 'Echocardiography', 'Enzyme-Linked Immunosorbent Assay', 'Gene Deletion', 'Immunohistochemistry', 'In Situ Nick-End Labeling', 'Interleukin-1', 'Interleukin-18', 'Matrix Metalloproteinase ... | 12,788,386 | [['B01.050'], ['G04.146.954.035'], ['D03.633.100.103.145'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D08.811.277.656.262.500.126.550.100', 'D08.811.277.656.300.200.126.550.100', 'D12.644.360.075.405.550.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Prediabetes, diabetes, and risk of breast cancer: a case-control study. | BACKGROUND AND AIMS: Although underlying mechanisms have been described to account for the association between prediabetes and diabetes with breast cancer, reported results have been inconsistent. We undertook this study to determine whether prediabetes and diabetes are risk factors for breast cancer in Mexican women w... | ['Adult', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Case-Control Studies', 'Confidence Intervals', 'Diabetes Complications', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Logistic Models', 'Mexico', 'Middle Aged', 'Multivariate Analysis', 'Odds Ratio', 'Prediabetic State', 'Prevalence', 'Risk Factors', 'Sel... | 24,937,172 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['C19.246.099'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Innovation in neurosurgery: Walter Dandy in his day. | In 1925, Walter Dandy published a preliminary report of an innovative operative procedure for patients with tic douloureux. Dandy reported treating tic by selectively sectioning the trigeminal nerve at the brain stem. His operative field was the cerebellopontine angle, which he exposed using a cerebellar approach. It i... | ['History, 20th Century', 'Humans', 'Neurosurgery', 'Trigeminal Nerve', 'Trigeminal Neuralgia', 'United States'] | 6,374,495 | [['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.425'], ['A08.800.800.120.760'], ['C07.465.299.625.500.700', 'C10.292.319.625.700.700'], ['Z01.107.567.875']] | ['Humanities [K]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
T2 mapping of rat patellar cartilage. | PURPOSE: To investigate the usefulness of magnetic resonance (MR) T2 mapping in characterizing the evolution of cartilage matrix content and thickness during the maturation and aging process.MATERIALS AND METHODS: Patellae from four groups of rats aged 4 weeks, 8 weeks, 4 months, and more than 6 months ("old rats") wer... | ['Aging', 'Animals', 'Cartilage, Articular', 'Chondroitin Sulfate Proteoglycans', 'Collagen', 'Hydroxyproline', 'Magnetic Resonance Imaging', 'Male', 'Patella', 'Rats', 'Rats, Wistar'] | 11,323,463 | [['G07.345.124'], ['B01.050'], ['A02.165.407.150', 'A02.835.583.192'], ['D09.698.735.200', 'D12.776.395.650.750'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D12.125.072.401.623.478'], ['E01.370.350.825.500'], ['A02.835.232.043.650.624', 'A02.835.232.730.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Urethral carcinoma and hyperplasia in male and female B6C3F1 mice treated with 3,3',4,4'-tetrachloroazobenzene (TCAB). | B6C3F1 mice chronically exposed to 3,3',4,4'-tetrachloroazobenzene (TCAB), a contaminant of dichloroaniline-derived herbicides, developed a number of neoplastic and nonneoplastic lesions, including carcinoma of the urinary tract. Groups of fifty male and fifty female B6C3F1 mice were exposed by gavage to TCAB at dose l... | ['Animals', 'Azo Compounds', 'Carcinogens', 'Carcinoma, Transitional Cell', 'Chlorobenzenes', 'Female', 'Herbicides', 'Hyperplasia', 'Kidney Diseases', 'Male', 'Mice', 'Ureteral Neoplasms', 'Urethral Diseases', 'Urethral Neoplasms', 'Urinary Bladder Neoplasms'] | 20,233,943 | [['B01.050'], ['D02.172'], ['D27.888.569.100'], ['C04.557.470.200.430'], ['D02.455.426.559.389.261', 'D02.455.526.439.202'], ['D27.720.031.700.366', 'D27.888.723.366'], ['C23.550.444'], ['C12.777.419', 'C13.351.968.419'], ['B01.050.150.900.649.313.992.635.505.500'], ['C04.588.945.947.940', 'C12.758.820.875', 'C12.777.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of an intervention to reduce antibiotic use for childhood coughs in UK primary care using critical synthesis of multi-method research. | BACKGROUND: Overuse of antibiotics contributes to the global threat of antimicrobial resistance. Antibiotic stewardship interventions address this threat by reducing the use of antibiotics in occasions or doses unlikely to be effective. We aimed to develop an evidence-based, theory-informed, intervention to reduce anti... | ['Anti-Bacterial Agents', 'Child', 'Child, Preschool', 'Clinical Trials as Topic', 'Cough', 'Dose-Response Relationship, Drug', 'Evidence-Based Practice', 'Feasibility Studies', 'Humans', 'Primary Health Care', 'Prospective Studies', 'Reproducibility of Results', 'Research Design', 'United Kingdom'] | 29,281,974 | [['D27.505.954.122.085'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['C08.618.248', 'C23.888.852.293'], ['G07.690.773.875', 'G07.690.936.500'], ['H02.249'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Thyroid lesions in patients with acromegaly - case-control study and update to the meta-analysis. | INTRODUCTION: Acromegaly results from oversecretion of growth hormone and subsequently insulin growth factor-1. According to some authors, the disease can cause increased prevalence of nodular goitre and thyroid cancer (TC). However, the number of studies comparing acromegalic patients with control groups is low. We ai... | ['Acromegaly', 'Adult', 'Aged', 'Case-Control Studies', 'Female', 'Goiter, Nodular', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Thyroid Gland', 'Thyroid Neoplasms'] | 28,255,974 | [['C05.116.132.082', 'C10.228.140.617.738.250.100', 'C19.700.355.179'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C19.874.283.501'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A solitary laryngeal neurofibroma ina pediatric patient. | A neurofibroma of the larynx is a rare disease that usually involves the arytenoids and the aryepiglottic fold. Pediatric patients with a laryngeal neurofibroma often present with progressive dyspnea. A definitive diagnosis of a laryngeal neurofibroma is based on the histopathologic demonstration of the characteristic ... | ['Child, Preschool', 'Female', 'Humans', 'Immunohistochemistry', 'Laryngeal Neoplasms', 'Laryngoscopy', 'Larynx', 'Neurofibroma', 'S100 Proteins'] | 15,754,784 | [['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['C04.588.443... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Isolation and characterization of a human cDNA encoding uracil-DNA glycosylase. | DNA repair of genetic information is an essential defense mechanism, which protects cells against mutation and transformation. The biochemistry of human DNA repair is in its beginning stages. Our research has concentrated on the enzymes involved in the removal of atypical bases from DNA. We present information on the i... | ['Amino Acid Sequence', 'Base Sequence', 'Blotting, Northern', 'Blotting, Western', 'Cell Line', 'DNA Glycosylases', 'DNA, Neoplasm', 'HeLa Cells', 'Humans', 'Molecular Sequence Data', 'Molecular Weight', 'N-Glycosyl Hydrolases', 'Open Reading Frames', 'Protein Biosynthesis', 'RNA, Messenger', 'Sequence Homology, Nucle... | 2,001,396 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210'], ['D08.811.074.249', 'D08.811.277.450.430.09... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Autologous transplantation of Ph-negative peripheral blood stem cells for treatment of chronic myelogenous leukemia]. | A 21-year-old man, diagnosed in March 1997 as having chronic myelogenous leukemia (CML), received hydroxyurea followed by daily interferon (IFN) until December 1998, when the additional chromosome abnormality of +8 appeared. As no suitable matched donor was available, the patient received mobilization therapy consistin... | ['Adult', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'In Situ Hybridization, Fluorescence', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Male', 'Philadelphia Chromosome', 'Transplantation, Autologous'] | 11,020,996 | [['M01.060.116'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.750.600.670.325.350', 'E05.393.285.350', 'E05.393.661.475.350'], ['C04.557.337.539.250', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cellular uptake of 3,5,3'-triiodothyronine and thyroxine by red blood and thymus cells. | During recent studies of receptor binding of T3 and T4 in tadpole red blood cells (RBCs), it was found that the fractional uptake of T3 was 3-5 times greater than that of T4. The present studies were performed to determine if this difference was due to facilitated uptake of T3. All studies were performed in cells incub... | ['Animals', 'Biological Transport', 'Cytosol', 'Erythrocytes', 'Humans', 'Kinetics', 'Larva', 'Male', 'Rana catesbeiana', 'Rats', 'Rats, Inbred Strains', 'Thymus Gland', 'Thyroxine', 'Triiodothyronine'] | 3,486,116 | [['B01.050'], ['G03.143'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B01.050.150.900.090.180.708.180'], ['B01.050... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nondepleting anti-CD4 monoclonal antibody prevents diabetes and blocks induction of insulin autoantibodies following insulin peptide B:9-23 immunization in the NOD mouse. | INTRODUCTION: Insulin peptide B:9-23 is a major autoantigen in type 1 diabetes that induces insulin autoantibodies and prevents diabetes in the NOD. However, immunization with peptide without adjuvant may be insufficient to reverse disease or induce long-term tolerance. Furthermore, recent experience has demonstrated t... | ['Adoptive Transfer', 'Animals', 'Antibodies', 'Antibodies, Monoclonal', 'Autoantibodies', 'Blood Glucose', 'CD4 Antigens', 'Cyclophosphamide', 'Diabetes Mellitus, Type 1', 'Female', 'Insulin', 'Insulin Antibodies', 'Islets of Langerhans', 'Mice', 'Mice, Inbred NOD', 'Mice, SCID', 'Peptide Fragments', 'Spleen', 'Surviv... | 14,599,846 | [['E02.095.465.425.400.330.050', 'E05.478.550.520.050'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Correlation between the lateral pterygoid muscle attachment type and temporomandibular joint disc position in magnetic resonance imaging. | OBJECTIVES: The aim of this study was to investigate the correlation between the lateral pterygoid muscle (LPM) attachment type and temporomandibular joint (TMJ) disc position on sagittal and coronal MR scans.METHODS: 191 patients (148 females, 43 males), aged 14-60 years, underwent MR investigations of the TMJs in the... | ['Adolescent', 'Adult', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Pterygoid Muscles', 'Temporomandibular Joint Disc', 'Young Adult'] | 27,506,381 | [['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['A02.633.567.600.700', 'A14.530.790'], ['A02.835.583.861.900', 'A14.907.900'], ['M01.060.116.815']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regulation of aldosterone secretion during altered sodium intake. | The interactions of the renin-angiotensin system with other factors in the regulation of aldosterone secretion were analyzed during altered sodium in the rat. During sodium restriction, the rise in aldosterone one secretion was accompanied by trophic changes in the adrenal glomerulosa zone including increased angiotens... | ['Adrenal Cortex', 'Aldosterone', 'Angiotensin II', 'Animals', 'Cell Membrane', 'Diet, Sodium-Restricted', 'Hypophysectomy', 'Metoclopramide', 'Pituitary Gland', 'Rats', 'Receptors, Angiotensin', 'Receptors, Cell Surface', 'Receptors, Somatostatin', 'Sodium', 'Somatostatin'] | 6,136,631 | [['A06.300.071.140'], ['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['A11.284.149'], ['E02.642.249.290', 'G07.203.650.240.290'], ['E04.270.532', 'E04... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Corrosion cast studies of the bronchial arteries. | The bronchial a. are the nutrient vessels of the lung. Despite being high pressure (systemic) vessels they are of very small size compared to the pulmonary a. and their side branches are normally so minute that they are extremely difficult to visualize during in vivo studies--yet these branches also supply many importa... | ['Adult', 'Aorta, Thoracic', 'Bronchi', 'Bronchial Arteries', 'Child', 'Humans', 'Pulmonary Artery'] | 2,588,098 | [['M01.060.116'], ['A07.015.114.056.372'], ['A04.411.125'], ['A07.015.114.158'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.715']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Increased detection of cystic-fibrosis-related diabetes in Australia. | OBJECTIVES: To estimate the incidence of cystic-fibrosis-related diabetes (CFRD) in youth from New South Wales (NSW) and the Australian Capital Territory (ACT), Australia and to examine demographic/clinical features at diagnosis.METHODS: Incident cases of CFRD in young people aged ? 18 years diagnosed during 2000 to 20... | ['Adolescent', 'Australian Capital Territory', 'Child', 'Child, Preschool', 'Cystic Fibrosis', 'Diabetes Mellitus', 'Drug Administration Schedule', 'Female', 'Glucose Tolerance Test', 'Glycated Hemoglobin A', 'Humans', 'Hypoglycemic Agents', 'Incidence', 'Infant', 'Infant, Newborn', 'Insulin', 'Male', 'New South Wales'... | 21,653,750 | [['M01.060.057'], ['Z01.639.100.500', 'Z01.678.100.373.500'], ['M01.060.406'], ['M01.060.406.448'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['C18.452.394.750', 'C19.246'], ['E02.319.283'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['D09.400.430.937', 'D12.776.124.400.4... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Engineered and Native Coenzyme B12-dependent Isovaleryl-CoA/Pivalyl-CoA Mutase. | Adenosylcobalamin-dependent isomerases catalyze carbon skeleton rearrangements using radical chemistry. We have recently demonstrated that an isobutyryl-CoA mutase variant, IcmF, a member of this enzyme family that catalyzes the interconversion of isobutyryl-CoA and n-butyryl-CoA also catalyzes the interconversion betw... | ['Acyl Coenzyme A', 'Amino Acid Sequence', 'Cobamides', 'Intramolecular Transferases', 'Kinetics', 'Molecular Sequence Data', 'Protein Conformation', 'Recombinant Proteins', 'Sequence Homology, Amino Acid', 'Substrate Specificity', 'Xanthobacter'] | 26,134,562 | [['D03.633.100.759.646.138.382.300', 'D08.211.211.300', 'D13.695.667.138.382.300', 'D13.695.827.068.382.300'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D03.383.129.578.840.437.777.270', 'D03.633.400.909.437.777.270', 'D04.345.783.437.777.270', 'D08.211.175'], ['D08.811.399.520'], ['G01.374.661', 'G02.111.490'], ['... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Modulation of the locomotory capacity of human large granular lymphocytes. | The regulation of the migratory capacity of Percoll-purified large granular lymphocytes (LGL) into nitrocellulose filters was studied in a 2-hr assay with the use of modified Boyden chambers. Compounds that stimulate the natural killer cytotoxic function of LGL, such as interferons (natural beta, recombinant alpha A, r... | ['Adjuvants, Immunologic', 'Cell Movement', 'Chemotaxis, Leukocyte', 'Cytotoxicity, Immunologic', 'Humans', 'Interferon Type I', 'Interleukin-2', 'Killer Cells, Natural', 'Phorbol Esters', 'Picibanil'] | 3,488,820 | [['D27.505.696.477.067'], ['G04.198', 'G07.568.500.180'], ['G04.198.424.233'], ['G12.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.4... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A simple and sensitive HPLC-UV method for quantitation of lovastatin in human plasma: application to a bioequivalence study. | An available, simple, sensitive, and rapid method has been developed for determination of the 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitor, lovastatin in human plasma. The analytical procedure involves a one-step liquid-liquid extraction method using atorvastatin as internal standard. Chromatographic separa... | ['Analysis of Variance', 'Chromatography, High Pressure Liquid', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Lovastatin', 'Male', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Spectrophotometry, Ultraviolet', 'Therapeutic Equivalency', 'Young Adult'] | 19,721,239 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.505.954.557.500.202.370'], ['D02.455.426.559.847.638.400', 'D04.615.638.400'], ['E05.318.370.725', 'E05.337.851', 'N05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Posttraumatic growth and PTSD symptomatology among colorectal cancer survivors: a 3-month longitudinal examination of cognitive processing. | INTRODUCTION: The experience of cancer can be understood as a psychosocial transition, producing both positive and negative outcomes. Cognitive processing may facilitate psychological adjustment.METHODS: Fifty-five post-treatment, colorectal cancer survivors (M=65.9 years old; SD=12.7), an average of 13 months post-dia... | ['Adaptation, Psychological', 'Aged', 'Cognition', 'Colorectal Neoplasms', 'Female', 'Humans', 'Kentucky', 'Male', 'Regression Analysis', 'Social Desirability', 'Stress Disorders, Post-Traumatic', 'Survivors'] | 18,481,837 | [['F01.058'], ['M01.060.116.100'], ['F02.463.188'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.075.400', 'Z01.107.567.875.510.400'], ['E05.318.740.750',... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hemin is kinetically trapped in cytochrome b(5) from rat outer mitochondrial membrane. | Cytochrome b(5) from the outer mitochondrial membrane of rat liver (OM cyt b(5)) is substantially more stable to thermal and chemical denaturation than cytochrome b(5) from the endoplasmic reticulum of bovine liver (microsomal, or Mc cyt b(5)). In contrast, the corresponding apoproteins have similar stability, suggesti... | ['Animals', 'Cattle', 'Cytochromes b5', 'Drug Stability', 'Endoplasmic Reticulum', 'Hemin', 'In Vitro Techniques', 'Intracellular Membranes', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Mitochondria, Liver', 'Protein Denaturation', 'Protein Isoforms', 'Rats', 'Recombinant Proteins', 'Thermodynamics'] | 10,873,629 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D08.244.187.500', 'D12.776.422.220.187.500'], ['E05.916.330'], ['A11.284.430.214.190.875.248'], ['D03.383.129.578.840.500.640.587.462', 'D03.633.400.909.500.640.587.462', 'D04.345.783.500.640.587.462', 'D23.767.727.640.587.462'], ['E05.481'], ['A11.284.149.450', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of Anxiety, Health Anxiety and Somatosensory Amplification Levels in Individuals with Benign Paroxysmal Positional Vertigo. | OBJECTIVES: Psychiatric comorbidities may intensify peripheral vertigo and increase the number of repositioning maneuvers required. This study was designed to examine the relationship between benign paroxysmal positional vertigo (BPPV) and anxiety and assess its association with somatic amplification and health anxiety... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anxiety', 'Benign Paroxysmal Positional Vertigo', 'Case-Control Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Patient Positioning', 'Physical Therapy Modalities', 'Prospective Studies', 'Psychiatric Status Rating Scales', 'Somatosensory Disorders', 'Young Adult'] | 31,347,508 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.470.132'], ['C09.218.568.900.883.500', 'C10.597.951.500', 'C23.888.592.958.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.760.670', 'N0... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification of a cell surface-binding protein for the core protein of the basement membrane proteoglycan. | We have identified a protein(s) on the surface of hepatocytes that binds to the core protein of the heparan sulfate proteoglycan of basement membranes. These cells attached and spread on substrates prepared from the basement membrane heparan sulfate proteoglycan (HSPG) and its core protein (HSPG-core). Three proteins (... | ['Animals', 'Basement Membrane', 'Cell Adhesion', 'Cell Line', 'Cell Membrane', 'Cells, Cultured', 'Chondroitin Sulfate Proteoglycans', 'Glycosaminoglycans', 'Heparan Sulfate Proteoglycans', 'Heparitin Sulfate', 'Kinetics', 'Liver', 'Membrane Glycoproteins', 'Molecular Weight', 'Proteoglycans', 'Rats', 'Rats, Inbred St... | 2,526,126 | [['B01.050'], ['A10.272.220', 'A10.615.179'], ['G04.022'], ['A11.251.210'], ['A11.284.149'], ['A11.251'], ['D09.698.735.200', 'D12.776.395.650.750'], ['D09.698.373'], ['D09.698.373.425.500', 'D09.698.735.400', 'D12.776.395.650.350'], ['D09.698.373.425'], ['G01.374.661', 'G02.111.490'], ['A03.620'], ['D12.776.395.550', ... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Red Queen race between parasitic chytrids and their host, Planktothrix: a test using a time series reconstructed from sediment DNA. | Parasitic chytrid fungi (phylum Chytridiomycota) are known to infect specific phytoplankton, including the filamentous cyanobacterium Planktothrix. Subspecies, or chemotypes of Planktothrix can be identified by the presence of characteristic oligopeptides. Some of these oligopeptides can be associated with important he... | ['Animals', 'Biological Evolution', 'Chytridiomycota', 'DNA, Fungal', 'Environmental Monitoring', 'Geologic Sediments', 'Host-Pathogen Interactions', 'Lakes', 'Norway', 'Parasites', 'Phytoplankton', 'Polymerase Chain Reaction', 'Time Factors'] | 25,793,898 | [['B01.050'], ['G05.045', 'G16.075'], ['B01.300.283'], ['D13.444.308.300'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.330', 'G16.500.320'], ['G06.462', 'G16.527.200'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['Z01.542.816.374'], ['B01.050.500.714'], ['B05.080.500.600'], ['E05.393.620.500'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Lymphotoxin beta receptor (Lt betaR): dual roles in demyelination and remyelination and successful therapeutic intervention using Lt betaR-Ig protein. | Inflammation mediated by macrophages is increasingly found to play a central role in diseases and disorders that affect a myriad of organs, prominent among these are diseases of the CNS. The neurotoxicant-induced, cuprizone model of demyelination is ideally suited for the analysis of inflammatory events. Demyelination ... | ['Animals', 'Apoptosis', 'Brain', 'Cell Division', 'Corpus Callosum', 'Cuprizone', 'Demyelinating Diseases', 'Immunoglobulin G', 'Lymphotoxin beta Receptor', 'Macrophages', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Microglia', 'Myelin Sheath', 'Oligodendroglia', 'Recombinant Fusion Proteins', 'Time Factors', 'Tu... | 17,626,203 | [['B01.050'], ['G04.146.954.035'], ['A08.186.211'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A08.186.211.200.885.800.750'], ['D02.455.426.392.368.367.190'], ['C10.314'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['D12.77... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Percutaneous chemolitholysis of cystine stones. Possibilities for ambulatory procedure. | We report on a patient with symptomatic cystine calculi in a solitary kidney in whom percutaneous pelviocaliceal irrigation with tromethamine-E was performed as an ambulatory procedure for a significant period of time. Our experience demonstrates that in selected cases this form of treatment is well-tolerated. | ['Adult', 'Ambulatory Care', 'Cystine', 'Cystinuria', 'Humans', 'Kidney Calculi', 'Male', 'Therapeutic Irrigation', 'Tromethamine'] | 3,360,041 | [['M01.060.116'], ['E02.760.106', 'N02.421.585.106'], ['D01.248.497.158.874.390.369', 'D01.875.350.850.150.369', 'D02.886.030.230.369', 'D02.886.520.150.087', 'D12.125.095.369', 'D12.125.119.369', 'D12.125.166.230.369'], ['C12.777.419.815.885.250', 'C13.351.968.419.815.885.250', 'C16.320.831.885.250'], ['B01.050.150.90... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of basic fibroblast growth factor on perforated chinchilla tympanic membranes. | Basic fibroblast growth factor (bFGF) is a polypeptide mitogen which stimulates proliferation of epidermal and connective tissue cells. When applied to tympanic membrane perforations it has been reported to enhance healing and produce connective tissue hyperplasia. Previous work with animal models has shown that hyperp... | ['Animals', 'Chinchilla', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Fibroblast Growth Factor 2', 'Injections, Intralesional', 'Survival Rate', 'Tympanic Membrane', 'Tympanic Membrane Perforation', 'Wound Healing'] | 9,282,463 | [['B01.050'], ['B01.050.150.900.649.313.992.328'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['E02.319.267.530.430'], ['E05.318.308.985.550.900', 'N01.224.935.698.826', 'N06.850.505.400.975.550.900', 'N06.850... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The Expression of Lung Resistance Protein in Saliva: A Novel Prognostic Indicator Protein for Carcinoma of the Breast. | Considering that saliva is a fluid inundated with proteins, it is possible that solubilized oncogenic proteins may be present in saliva and may be useful in differentiating between healthy and diseased individuals. As a consequence, the purpose of this study was to determine if the solubilized form of LRP was present i... | ['Adult', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Female', 'Humans', 'Middle Aged', 'Prognosis', 'Saliva', 'Vault Ribonucleoprotein Particles'] | 26,506,284 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789'], ['A12.200.666'], ['A11.284.430.214.190.875.930', 'D12.776.157.725.500.937', 'D12.776.664.962.500.937']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Monitoring rarity: the critically endangered Saharan cheetah as a flagship species for a threatened ecosystem. | Deserts are particularly vulnerable to human impacts and have already suffered a substantial loss of biodiversity. In harsh and variable desert environments, large herbivores typically occur at low densities, and their large carnivore predators occur at even lower densities. The continued survival of large carnivores i... | ['Acinonyx', 'Algeria', 'Animals', 'Biodiversity', 'Desert Climate', 'Ecosystem', 'Geography', 'Humans', 'Population Density', 'Predatory Behavior'] | 25,629,400 | [['B01.050.150.900.649.313.750.377.750.030'], ['Z01.058.266.104'], ['B01.050'], ['G16.500.275.157.049', 'N06.230.124.049'], ['G16.500.275.071.325', 'N06.230.300.100.250.325'], ['G16.500.275.157', 'N06.230.124'], ['H01.277.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.224.600', 'N06.850.505.400.600'], ['... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
IL-10, but not IL-4, suppresses infection-stimulated bone resorption in vivo. | Periapical bone resorption occurs following infection of the dental pulp and is mediated mainly by IL-1alpha in the murine model. The production and activity of IL-1alpha is modulated by a network of regulatory cytokines, including those produced by Th1 (pro-inflammatory) and Th2 (anti-inflammatory) subset T cells. Thi... | ['Animals', 'Bone Resorption', 'Cells, Cultured', 'Cytokines', 'Disease Models, Animal', 'Gram-Negative Bacterial Infections', 'Gram-Positive Bacterial Infections', 'Immunosuppressive Agents', 'Interleukin-1', 'Interleukin-10', 'Interleukin-4', 'Macrophages, Peritoneal', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, In... | 11,034,365 | [['B01.050'], ['C05.116.264', 'G11.427.213.150'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C01.150.252.400'], ['C01.150.252.410'], ['D27.505.696.477.656'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.7... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A new theory of phylogeny inference through construction of multidimensional vector space. | Here, a new theory of molecular phylogeny is developed in a multidimensional vector space (MVS). The molecular evolution is represented as a successive splitting of branch vectors in the MVS. The end points of these vectors are the extant species and indicate the specific directions reflected by their individual histor... | ['Amino Acid Sequence', 'Amino Acid Substitution', 'Animals', 'Hemoglobins', 'Models, Genetic', 'Models, Theoretical', 'Molecular Sequence Data', 'Monte Carlo Method', 'Peptide Fragments', 'Phylogeny', 'Probability', 'Radiation Genetics', 'Species Specificity', 'Vertebrates'] | 11,319,265 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['D12.776.124.400', 'D12.776.422.316.762'], ['E05.599.395.397'], ['E05.599'], ['L01.453.245.667'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['D12.644.541'], ['G05.697', 'G16.075... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Anti-adipogenic and antiviral effects of l-carnitine on hepatitis C virus infection. | Hepatitis C virus (HCV) has been reported to hijack fatty acid metabolism in infected hepatocytes, taking advantage of lipid droplets for virus assembly. In this study, we analyzed the anti-HCV activity of l-carnitine, a substance involved in the transport of fatty acids into mitochondria. JFH-1 or HCV replicon-transfe... | ['Anti-Obesity Agents', 'Antiviral Agents', 'Carnitine', 'Cell Line', 'Hepacivirus', 'Hepatocytes', 'Humans', 'Lipid Droplets', 'Virus Assembly'] | 27,664,407 | [['D27.505.954.203'], ['D27.505.954.122.388'], ['D02.092.877.883.099'], ['A11.251.210'], ['B04.450.380', 'B04.820.578.344.475'], ['A11.436.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.875.393'], ['G06.920.925.950']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Caregiver evaluation of the ACTIVE intervention: "it was like we were sitting at the table with everyone". | Central to the hospice philosophy is the belief that the patient/family owns the plan of care. However, barriers prevent the majority of hospice patients/families from participating in the meetings where plans are created and revised. This study evaluates the participant experience of the ACTIVE (assessing caregivers f... | ['Adult', 'Aged', 'Caregivers', 'Female', 'Hospice Care', 'Humans', 'Interviews as Topic', 'Male', 'Middle Aged', 'Patient Care Team', 'Precision Medicine', 'Young Adult'] | 23,713,130 | [['M01.060.116'], ['M01.060.116.100'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['E02.760.905.400', 'N02.421.585.905.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['M01.060.116.630'], ['N04.590.715'], ['E02.782', 'H02.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Resistin promotes cardiac homing of mesenchymal stem cells and functional recovery after myocardial ischemia-reperfusion via the ERK1/2-MMP-9 pathway. | Stem cell therapy is a potentially effective and promising treatment for ischemic heart disease. Resistin, a type of adipokine, has been found to bind to adipose-derived mesenchymal stem cells (ADSCs). However, the effects of resistin on cardiac homing by ADSCs and on ADSC-mediated cardioprotective effects have not bee... | ['Adipose Tissue', 'Animals', 'Apoptosis', 'Cardiac Output', 'Cell Movement', 'Cells, Cultured', 'MAP Kinase Signaling System', 'Male', 'Matrix Metalloproteinase 9', 'Mesenchymal Stem Cell Transplantation', 'Mesenchymal Stem Cells', 'Mice', 'Mice, Inbred C57BL', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated ... | 30,412,442 | [['A10.165.114'], ['B01.050'], ['G04.146.954.035'], ['E01.370.370.380.150', 'G09.330.380.124'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['D08.811.277.656.300.480.205.360', 'D08.811.277.656.300.480.252.445', 'D08.811.277.656.300.480.525.700.350', 'D08.811.277.656.6... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Associations between circulating free fatty acids, visceral adipose tissue accumulation, and insulin sensitivity in postmenopausal women. | The aims of the study were to evaluate the contribution of visceral adipose tissue (AT) accumulation and insulin sensitivity to the determination of circulating free fatty acid (FFA) concentrations measured during a 2-hour euglycemic-hyperinsulinemic clamp and to verify whether elevated FFAs are associated with other c... | ['Aged', 'Body Mass Index', 'Cross-Sectional Studies', 'Fatty Acids, Nonesterified', 'Female', 'Glucose Clamp Technique', 'Humans', 'Insulin Resistance', 'Intra-Abdominal Fat', 'Metabolic Syndrome', 'Middle Aged', 'Postmenopause', 'Subcutaneous Fat'] | 19,154,950 | [['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D10.251.310'], ['E01.370.225.124.100.350', 'E05.196.500', 'E05.200.124.100.350'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Steady state visually evoked potential (SSVEP) topography in a graded working memory task. | The steady state visually evoked potential (SSVEP) elicited by a diffuse 13-Hz visual flicker was recorded from 64 scalp sites in 30 subjects performing a low and high demand version of an object working memory task. During the perceptual component of the task, the SSVEP amplitude was reduced at left and right parieto-... | ['Adult', 'Biofeedback, Psychology', 'Brain Mapping', 'Cerebral Cortex', 'Evoked Potentials, Visual', 'Humans', 'Male', 'Memory', 'Neural Pathways', 'Photic Stimulation', 'Thalamus'] | 11,587,778 | [['M01.060.116'], ['E02.190.525.123', 'F02.830.131', 'F04.754.137.301', 'F04.754.308.500'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.42... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A durable, low-cost electrogoniometer for dynamic measurement of joint trajectories. | This article introduces a method and step-by-step instructions for the design of a low-cost, flexible electrogoniometer, suitable for kinesiology, rehabilitation, and biometric applications. Two unidirectional flexible sensors are placed back-to-back, and a multivariate linear regression model was used to combine measu... | ['Adult', 'Arthrometry, Articular', 'Electricity', 'Equipment Failure', 'Female', 'Humans', 'Joints', 'Male', 'Middle Aged', 'Movement', 'Young Adult'] | 21,247,789 | [['M01.060.116'], ['E01.370.600.700.500', 'G11.427.760.500'], ['G01.358.500.249'], ['E05.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583'], ['M01.060.116.630'], ['G07.568', 'G11.427.410'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Establishment of an interleukin-5-dependent subclone from an interleukin-3-dependent murine hemopoietic progenitor cell line, LyD9, and its malignant transformation by autocrine secretion of interleukin-5. | An interleukin-5 (IL-5)-dependent subclone, K-5, was established from an IL-3-dependent murine hemopoietic progenitor cell line by co-culturing with bone marrow stroma cells. K-5 cells were induced to differentiate into myeloid lineage cells by co-culturing with cloned PA6 stroma cells. By co-culturing with another clo... | ['Animals', 'Base Sequence', 'Cell Differentiation', 'Cell Line', 'Cell Transformation, Neoplastic', 'Clone Cells', 'DNA', 'Gene Expression Regulation', 'Genes, Intracisternal A-Particle', 'Hematopoietic Stem Cells', 'Interleukin-3', 'Interleukin-5', 'Mice', 'Mice, Nude', 'Molecular Sequence Data', 'Organ Specificity',... | 2,112,086 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.152'], ['A11.251.210'], ['C04.697.098.500', 'C23.550.727.098.500'], ['A11.251.353'], ['D13.444.308'], ['G05.308'], ['G02.111.570.080.708.330.800.200', 'G05.360.080.708.330.800.200', 'G05.360.340.024.340.364.875.360', 'G05.360.340.024.425.800... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Short-term effects of postural drainage with clapping vs autogenic drainage on oxygen saturation and sputum recovery in patients with cystic fibrosis. | To compare the short-term effects of postural drainage with clapping (PD) and autogenic drainage (AD) on oxygen saturation, pulmonary function, and sputum recovery, we studied ten patients with cystic fibrosis (CF) randomly treated with PD or AD on separate days. Pulse oximetry was monitored and sputum was collected du... | ['Adolescent', 'Adult', 'Analysis of Variance', 'Child', 'Cystic Fibrosis', 'Drainage, Postural', 'Female', 'Humans', 'Lung', 'Male', 'Oxygen', 'Self Care', 'Sputum', 'Time Factors'] | 7,555,167 | [['M01.060.057'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['M01.060.406'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['E02.309.221', 'E02.779.358', 'E02.831.535.358', 'E02.880.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['D01.268.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Screening of Target Genes and Regulatory Function of miRNAs as Prognostic Indicators for Prostate Cancer. | BACKGROUND MicroRNAs expression profiling of prostate cancer is becoming increasingly used due to its usefulness in diagnosis, staging, prognosis, and response to treatment. The aim of this study was to screen differentially expressed miRNAs in prostate cancer and analyze the functions and signal pathways of their targ... | ['Biomarkers, Tumor', 'Case-Control Studies', 'Down-Regulation', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'MAP Kinase Signaling System', 'Male', 'MicroRNAs', 'Principal Component Analysis', 'Prognosis', 'Prostatic Neoplasms', 'ROC Curve', 'Up-Regulation'] | 26,628,405 | [['D23.101.140'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['E05.393.332'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['D13.150.650.319', 'D13.444.735.150.3... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Platelet modulation of polymorphonuclear leukocyte shear induced aggregation. | A cone and plate viscometer and Coulter Counter were used to study platelet modulation of polymorphonuclear leukocyte (PMNL) aggregation caused by controlled shear stress. As an index of aggregation, the large-particle percentage (LPP) was calculated. This represents the ratio of aggregated cell count to total cell cou... | ['Arachidonic Acid', 'Arachidonic Acids', 'Blood Platelets', 'Calcimycin', 'Cell Aggregation', 'Humans', 'Hydroxyeicosatetraenoic Acids', 'Leukotriene B4', 'Lipoxygenase', 'N-Formylmethionine Leucyl-Phenylalanine', 'Neutrophils'] | 3,000,480 | [['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['A11.118.188', 'A15.145.229.188'], ['D03.633.100.221.173'], ['G04.198.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.251.355.255.100.300', 'D10.251.355.310.166.550'], ['D10.251.355.255.100.450.411', ... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ex vivo and in vivo T cell-depleted allogeneic stem cell transplantation in patients with acute myeloid leukemia in first complete remission resulted in similar overall survival: on behalf of the ALWP of the EBMT and the MSKCC. | BACKGROUND: Graft-versus-host disease (GVHD) is one of the leading causes of non-relapse mortality and morbidity after allogeneic hematopoietic stem cell transplantation (allo-HCT).METHODS: We evaluated the outcomes of two well-established strategies used for GVHD prevention: in vivo T cell depletion using antithymocyt... | ['Adult', 'Aged', 'Female', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Leukemia, Myeloid, Acute', 'Male', 'Middle Aged', 'Survival Analysis', 'Transplantation Conditioning', 'Transplantation, Homologous', 'Young Adult'] | 30,342,553 | [['M01.060.116'], ['M01.060.116.100'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.275'], ['M01.060.116.630'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.850.520.830.998'], ['E02.095.465.425.450.800', 'E05.478.610.800'], ['E04.936.864'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Multitargeted Nanoparticles Deliver Synergistic Drugs across the Blood-Brain Barrier to Brain Metastases of Triple Negative Breast Cancer Cells and Tumor-Associated Macrophages. | Patients with brain metastases of triple negative breast cancer (TNBC) have a poor prognosis owing to the lack of targeted therapies, the aggressive nature of TNBC, and the presence of the blood-brain barrier (BBB) that blocks penetration of most drugs. Additionally, infiltration of tumor-associated macrophages (TAMs) ... | ['Animals', 'Apoptosis', 'Blood-Brain Barrier', 'Brain Neoplasms', 'Cell Line, Tumor', 'Disease Progression', 'Doxorubicin', 'Drug Delivery Systems', 'Drug Synergism', 'Female', 'Humans', 'Lipids', 'Macrophages', 'Mice', 'Mitomycin', 'Nanoparticles', 'Oligopeptides', 'RAW 264.7 Cells', 'Receptors, LDL', 'Survival Analy... | 31,348,614 | [['B01.050'], ['G04.146.954.035'], ['A07.035', 'A08.186.211.035'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['A11.251.210.190', 'A11.251.860.180'], ['C23.550.291.656'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['E02.319.300'], ['G07.690.773.968... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Detection of serum of IgG anti-neuronal antibodies in systemic lupus erythematosus patients with central nervous system manifestations. | The objective of the study was to assess the frequence of serum IgG anti-neuronal antibodies (NA) in SLE patints with CNS manifestations. Serum anti-NA antibodies were measured in 47 patients with SLE with CNS manifestations (CNS-SLE), age 33-52 years, mean age 38.6 years, 18 men and 29 women, as compared to 31 patient... | ['Adult', 'Antibodies', 'Female', 'Fluorescent Antibody Technique, Indirect', 'Humans', 'Immunoglobulin G', 'Lupus Vasculitis, Central Nervous System', 'Male', 'Middle Aged', 'Neurons'] | 21,528,753 | [['M01.060.116'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.551.512.240.310', 'E05.200.500.607.512.240.310', 'E05.200.750.551.512.240.310', 'E05.478.583.375.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Molecular phenotype of monocytes at the maternal-fetal interface. | OBJECTIVE: The purpose of this study was to gain insight into the pathways that are associated with inflammation at the maternal-fetal interface. This study examined the molecular characteristics of monocytes that were derived from the maternal circulation and the placenta of obese women.STUDY DESIGN: Mononuclear cells... | ['Adult', 'Female', 'Fetal Blood', 'Fetus', 'Gene Expression', 'Humans', 'Inflammation', 'Lipopolysaccharide Receptors', 'Monocytes', 'Obesity', 'Placenta', 'Pregnancy', 'Transcriptome'] | 22,071,058 | [['M01.060.116'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['A16.378'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['D12.776.395.550.448.100', 'D12.776.543.484.500.100', 'D12.776.543.550.418.100', 'D12.776.543.750.705.045', 'D23.050.301.264.900.045', 'D23.101.100.900.045'],... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Confronting racial disparities in infant mortality: reconciling science and politics. | The public debate surrounding disparities in infant mortality has resulted from a profound failure to seek a common wisdom. Because of its essential social roots, infant mortality will always remain the province of fundamental ideological and political conflict. However, without a more integrated analytic approach, pro... | ['African Americans', 'African Continental Ancestry Group', 'Birth Weight', 'Causality', 'European Continental Ancestry Group', 'Female', 'Health Policy', 'Humans', 'Infant Mortality', 'Infant, Newborn', 'Maternal Welfare', 'Socioeconomic Factors', 'United States', "Women's Health"] | 8,123,287 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.686.508.100'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['N05.715.350.200', 'N06.850.490.625'], ['M01.686.508.400'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Ancient differentiation in the single-island avian radiation of endemic Hispaniolan chat-tanagers (Aves: Calyptophilus). | The simple geographic structure of island systems often makes them tractable for studies of the patterns and processes of biological diversification. The Calyptophilus chat-tanagers of Hispaniola are of general evolutionary interest because their multiple lineages might have arisen on a single island, of conservation c... | ['Animals', 'Conservation of Natural Resources', 'DNA, Mitochondrial', 'Dominican Republic', 'Genetic Markers', 'Genetic Speciation', 'Geography', 'Haiti', 'Haplotypes', 'Passeriformes', 'Phylogeny'] | 17,845,436 | [['B01.050'], ['J01.256', 'N06.230.080'], ['D13.444.308.283.225'], ['Z01.107.084.900.300', 'Z01.639.880.300'], ['D23.101.387', 'G05.695.450'], ['G05.045.350', 'G16.075.350'], ['H01.277.500'], ['Z01.107.084.900.425', 'Z01.639.880.425'], ['G05.380.360'], ['B01.050.150.900.248.620'], ['G05.697', 'G16.075.605', 'L01.100.69... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
The public and private history of eugenics: an introduction. | Inspired by our experience addressing the legacy of eugenics at California State University, Sacramento, this special issue presents an array of articles representative of diverse approaches to the historical investigation of eugenics. This article provides an introduction to the history of eugenics and explores the wa... | ['Biotechnology', 'Eugenics', 'History, 20th Century', 'History, 21st Century', 'Humans', 'United States'] | 18,175,448 | [['H01.158.550', 'J01.897.120'], ['K01.400.307'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875']] | ['Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Humanities [K]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 |
A cross-sectional study of the feasibility of pharmacy-delivered harm reduction services among people who inject drugs in Xichang, China. | BACKGROUND: HIV prevalence is high in Liangshan, China (1.1 %). In 2012, people who inject drugs (PWID) in Xichang, the capital city, contributed to 60.0 % of the HIV infections. The goal of the current study was to examine the feasibility of implementing pharmacy-delivered harm reduction services (PDHRS) for PWID.METH... | ['Adolescent', 'Adult', 'China', 'Commerce', 'Cross-Sectional Studies', 'Female', 'HIV Infections', 'Harm Reduction', 'Hepatitis C', 'Humans', 'Male', 'Middle Aged', 'Needles', 'Patient Acceptance of Health Care', 'Pharmaceutical Services', 'Pharmacies', 'Risk Reduction Behavior', 'Substance Abuse, Intravenous', 'Syrin... | 26,370,245 | [['M01.060.057'], ['M01.060.116'], ['Z01.252.474.164'], ['J01.219'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['F01.145.477'], ['C01.221.250.750', 'C01.925.44... | ['Named Groups [M]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
[Ergonomic situation in stomatologic institutions of Tbilisi]. | Special working features of stomatology distinguishes it from other medical disciplines. This makes necessary to establish ergonomic environment of work for dentists and follow all necessary principles. The paper presents the major indices or ergonomic expertise in stomatologic institutions of Tbilisi, Georgia. It was ... | ['Dentistry', 'Ergonomics', 'Georgia (Republic)', 'Humans', 'Occupational Exposure', 'Occupational Health', 'Surveys and Questionnaires'] | 16,052,063 | [['E06', 'H02.163'], ['F02.784.412', 'J01.293.556'], ['Z01.542.900.420', 'Z01.542.931.420', 'Z01.586.950.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.600'], ['N01.400.525'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Application of a surface matching image registration technique to the correlation of cardiac studies in positron emission tomography (PET) by transmission images. | The aim of this work is to assess the accuracy of a surface matching registration (SMR) technique for the correlation of cardiac studies in positron emission tomography (PET). Registration parameters were estimated by matching corresponding body surfaces, extracted from transmission studies, aligned to the PET emission... | ['Computer Simulation', 'Heart', 'Humans', 'Phantoms, Imaging', 'Reproducibility of Results', 'Thorax', 'Tomography, Emission-Computed'] | 8,532,749 | [['L01.224.160'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.671'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['A01.923.761'], ['E01.370.350.350.800', 'E01.370.350.600.350.800', 'E01.370.350.710.800', 'E01.370.350.825.800', 'E01.370.384.730.800']] | ['Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Athetosis in typhoid fever. | A case of typhoid fever with neuropsychiatric features is described. These comprised confusion and delirium, meningism, a single major convulsion and bilateral athetoic movements. Athetosis has not previously been described in typhoid fever and must now be added to the long list of neuropsychiatric manifestations of th... | ['Adult', 'Athetosis', 'Humans', 'Male', 'Typhoid Fever'] | 3,701,678 | [['M01.060.116'], ['C10.597.350.110', 'C23.888.592.350.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.400.310.821.873']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Unrecognised compartment syndrome in a patient with tourniquet palsy. | We report a case in which compartment syndrome and tourniquet paralysis occurred simultaneously. This is a previously unreported combination which presents a diagnostic problem. We recommend that electrophysiological studies and continuous monitoring of compartment pressures should be used to minimise morbidity in high... | ['Adult', 'Ankle', 'Ankle Injuries', 'Anterior Compartment Syndrome', 'Compartment Syndromes', 'Diagnosis, Differential', 'Fractures, Bone', 'Humans', 'Male', 'Paralysis', 'Tourniquets'] | 3,102,499 | [['M01.060.116'], ['A01.378.610.050'], ['C26.558.100'], ['C05.651.180.063', 'C14.907.303.063'], ['C05.651.180', 'C14.907.303'], ['E01.171'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.622', 'C23.888.592.636'], ['E07.926']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Visual loss following traumatic asphyxia in children. | Two young children suffered loss of vision in separate incidents following traumatic asphyxia. Visual loss secondary to trauma can occur from a variety of causes. This is apparently the first description of traumatic asphyxia causing visual loss in children. In children, visual impairment is easily missed unless the de... | ['Asphyxia', 'Child', 'Female', 'Humans', 'Male', 'Optic Atrophy', 'Retinal Degeneration', 'Thoracic Injuries', 'Vision Disorders'] | 3,352,023 | [['C23.550.260.095', 'C26.103'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.292.700.225', 'C11.640.451'], ['C11.270.612', 'C11.768.585'], ['C26.891'], ['C10.597.751.941', 'C11.966', 'C23.888.592.763.941']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Contrast imaging by non-overlapping dual frequency band transmit pulse complexes. | SURF contrast imaging, as described previously in the literature, is a contrast agent detection technique achieved by processing of the received signals from transmitted dual frequency band pulse complexes with overlapping high-frequency (HF) and low-frequency (LF) pulses. The transmitted HF pulses are used for image r... | ['Computer Simulation', 'Contrast Media', 'Microbubbles', 'Nonlinear Dynamics', 'Signal Processing, Computer-Assisted', 'Ultrasonography'] | 21,342,814 | [['L01.224.160'], ['D27.505.259.500', 'D27.720.259'], ['E07.553'], ['E05.599.850', 'H01.548.675'], ['L01.224.800'], ['E01.370.350.850']] | ['Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Adult life behavioral consequences of early maternal separation are alleviated by escitalopram treatment in a rat model of depression. | In order to study the gene-environment interaction as well as investigate prophylactic/ameliorative effects of early intervention on development of adult life psychopathology, we superimposed maternal separation on an animal model of depression the Flinders Sensitive Line (FSL) rats and their controls the Flinders Resi... | ['Age Factors', 'Analysis of Variance', 'Animals', 'Animals, Newborn', 'Antidepressive Agents, Second-Generation', 'Behavior, Animal', 'Citalopram', 'Depression', 'Disease Models, Animal', 'Female', 'Male', 'Maternal Deprivation', 'Random Allocation', 'Rats', 'Swimming'] | 16,414,167 | [['N05.715.350.075', 'N06.850.490.250'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['B01.050.050.282'], ['D27.505.954.427.700.122.050'], ['F01.145.113'], ['D02.092.831.170', 'D02.626.320', 'D03.633.100.127.187'], ['F01.145.126.350'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], [... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Assessment and Maintenance of Unigametic Germline Inheritance for C. elegans. | The recent work of Besseling and Bringmann (2016) identified a molecular intervention for C. elegans in which premature segregation of maternal and paternal chromosomes in the fertilized oocyte can produce viable animals exhibiting a non-Mendelian inheritance pattern. Overexpression in embryos of a single protein regul... | ['Animals', 'Biomarkers', 'Caenorhabditis elegans', 'Caenorhabditis elegans Proteins', 'Chromosomes', 'Crosses, Genetic', 'Female', 'Fluorescence', 'Germ Cells', 'Inheritance Patterns', 'Male', 'Microtubules', 'Mosaicism', 'Mutation', 'Pharynx', 'Phenotype', 'Vulva', 'Zygote'] | 30,799,227 | [['B01.050'], ['D23.101'], ['B01.050.500.500.294.400.875.660.250.250'], ['D12.776.419.500'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['E05.393.281'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['A05.360.490', 'A11.497'], ['G05.420'], ['A11.284.430.214.190.750.602'], ['G05.365.590.175... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A previously unidentified sigma factor and two accessory proteins regulate oxalate decarboxylase expression in Bacillus subtilis. | We have investigated the function of a cell envelope stress-inducible gene, yvrI, which encodes a 22.5 kDa protein that includes a predicted sigma(70) region 4 domain, but lacks an apparent region 2 domain. YvrI interacts with RNA polymerase and overexpression of YvrI results in induction of OxdC, an oxalate decarboxyl... | ['Bacillus subtilis', 'Bacterial Proteins', 'Carboxy-Lyases', 'Enzyme Induction', 'Gene Expression Regulation, Bacterial', 'Oligonucleotide Array Sequence Analysis', 'Operon', 'Promoter Regions, Genetic', 'Regulon', 'Sigma Factor'] | 18,573,182 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['D08.811.520.224.125'], ['G05.308.320.200'], ['G05.308.300'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['G05.360.340.02... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of the group III metabotropic glutamate receptor in LTP, depotentiation and LTD in dentate gyrus of freely moving rats. | We investigated whether group III metabotropic glutamate (mGlu) receptors are critically involved in the expression of long-term potentiation (LTP), depotentiation, or long-term depression (LTD) in the dentate gyrus of freely moving rats. Male Wistar rats (7 8 weeks) underwent implantation of stimulating and recording ... | ['Animals', 'Behavior, Animal', 'Dentate Gyrus', 'Electric Stimulation', 'Excitatory Postsynaptic Potentials', 'Long-Term Potentiation', 'Long-Term Synaptic Depression', 'Male', 'Motor Activity', 'Propionates', 'Rats', 'Rats, Wistar', 'Receptors, Metabotropic Glutamate', 'Synaptic Transmission'] | 15,080,077 | [['B01.050'], ['F01.145.113'], ['A08.186.211.180.405.200', 'A08.186.211.200.885.287.500.345.200'], ['E05.723.402'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['G11.561.638.350'], ['G11.561.638.355'], ['F01.145.632', 'G11.427.410.698'], ['D02.241.081... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Seasonal Variation in Month of Diagnosis of Polish Children with Type 1 Diabetes - A Multicenter Study. | AIM: The seasonal variation of incidence of type 1 diabetes (T1D) theory supports the hypothesis that environmental factors play a role in the onset of the disease. The aim of this study is to assess seasonality of month of diagnosis in children with T1D in Poland.MATERIAL AND METHODS: the study group consisted of 2174... | ['Adolescent', 'Child', 'Child, Preschool', 'Diabetes Mellitus, Type 1', 'Female', 'Humans', 'Incidence', 'Infant', 'Male', 'Poland', 'Rural Population', 'Seasons', 'Urban Population'] | 29,506,312 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.703'], ['Z01.542.248.679'], ['N01.60... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Two new glycosidic acids, quamoclinic acids G and H, of the resin glycosides (Convolvulin) from the seeds of Quamoclit pennata. | Two new glycosidic acids, quamoclinic acids G and H, were isolated from the glycosidic acid fraction afforded by alkaline hydrolysis of the ether-insoluble resin glycoside (convolvulin) fraction from the seeds of Quamoclit pennata BOJER. Both compounds are the first examples of bisdesmosides of glycosidic acid having t... | ['Convolvulaceae', 'Glycosides', 'Magnetic Resonance Spectroscopy', 'Seeds'] | 20,823,606 | [['B01.650.940.800.575.912.250.238'], ['D09.408'], ['E05.196.867.519'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Postnatal changes of steroid receptor coactivator-1 immunoreactivity in rat cerebellar cortex. | Steroid receptor coactivator-1 (SRC-1) interacts with nuclear hormone receptors (NRs) to mediate their action in a ligand-dependent manner. Among such ligands, thyroid hormone (TH) is particularly crucial for brain development. The expression of many TH target genes is regulated by TH only for a limited critical period... | ['Animals', 'Blotting, Western', 'Cerebellar Cortex', 'Female', 'Histone Acetyltransferases', 'Immunohistochemistry', 'Nuclear Receptor Coactivator 1', 'Pregnancy', 'Rats', 'Rats, Sprague-Dawley', 'Thyroid Hormones', 'Transcription Factors'] | 15,876,152 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A08.186.211.132.810.428.200.212'], ['D08.811.913.050.134.415.500'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.23... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Systemic prophylactic antibiotics: need the 'cost' be so high? | To assess compliance with accepted principles, the use of prophylaxis with systemic antibiotics in selected specialty procedures was examined. The operations reviewed were aortofemoral bypass, pulmonary resections, open-hip procedures, and head-neck cancer procedures that involve the oropharyngeal cavity. Of all patien... | ['Anti-Bacterial Agents', 'Drug Utilization', 'Female', 'Head and Neck Neoplasms', 'Hip Fractures', 'Humans', 'Male', 'Middle Aged', 'Pneumonectomy', 'Postoperative Care', 'Preoperative Care', 'Surgical Wound Infection', 'Vascular Surgical Procedures'] | 7,213,003 | [['D27.505.954.122.085'], ['N04.452.706.477'], ['C04.588.443'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.620', 'E04.928.600.600'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.722.700'], ['E02.760.795', 'E04.604.750', 'N02.421.... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Language used in Lake Louise Scoring System underestimates symptoms of acute mountain sickness in 4- to 11-year-old children. | The Lake Louise Scoring System (LLSS) was designed to evaluate adults for symptoms of acute mountain sickness (AMS). The language used in the LLSS may be too complex for young children to comprehend. This study evaluates if age-appropriate language alters the results of AMS diagnostic scores in 4- to 11-yr-old children... | ['Acute Disease', 'Altitude Sickness', 'Child', 'Child Behavior', 'Child, Preschool', 'Colorado', 'Communication Barriers', 'Female', 'Humans', 'Male', 'Population Surveillance', 'Reference Values', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Severity of Illness Index', 'Surveys and Questionnaires'] | 17,584,006 | [['C23.550.291.125'], ['C08.618.020'], ['M01.060.406'], ['F01.145.179'], ['M01.060.406.448'], ['Z01.107.567.875.760.210'], ['L01.143.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980.438.700', 'N05.715.360.300.800.438.625', 'N06.850.520.308.980.438.700', 'N06.850.780.675'], ['E05.978.810'], ['E0... | ['Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Uni- and bilateral instrumented posterolateral fusion of the lumbar spine with local bone grafting: a prospective study with a 2-year follow-up. | STUDY DESIGN: Prospective trial.OBJECTIVE: To examine the bone union and clinical results after unilateral or bilateral instrumented posterolateral fusion surgery using a local bone graft.SUMMARY OF BACKGROUND DATA: The iliac crest bone graft technique for lumbar posterolateral fusion surgery is widely used; however, d... | ['Aged', 'Bone Transplantation', 'Decompression, Surgical', 'Disability Evaluation', 'Female', 'Follow-Up Studies', 'Humans', 'Ilium', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Pain Measurement', 'Prospective Studies', 'Spinal Fusion', 'Spinal Stenosis', 'Spondylolisthesis', 'Time Factors', 'Treatment Outcome'] | 21,544,013 | [['M01.060.116.100'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['E04.188'], ['E01.370.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043.825.434'], ['A02.835.232.834.519'], ['M01.060.116.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effects of smoking and its cessation on 8-epi-PGF2alpha and transforming growth factor-beta 1 in Type 1 diabetes mellitus. | BACKGROUND: Oxidative stress and transforming growth factor-beta 1 (TGF-beta1) are associated with diabetic complications, and smoking is a risk factor.AIMS: This study aimed (i) to compare urinary 8-epi-PGF2alpha and plasma and urinary TGF-beta1 levels obtained in heavy smokers with Type 1 diabetes with those observed... | ['Adult', 'Cotinine', 'Cross-Sectional Studies', 'Diabetes Mellitus, Type 1', 'Dinoprost', 'Female', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Immunoassay', 'Male', 'Smoking', 'Smoking Cessation', 'Transforming Growth Factor beta', 'Transforming Growth Factor beta1', 'Vasoconstrictor Agents'] | 15,008,841 | [['M01.060.116'], ['D03.383.773.812.180'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['D10.251.355.255.550.400.200', 'D23.469.050.175.725.400.200'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
SEOM clinical guidelines for the treatment of nasopharyngeal carcinoma 2013. | Nasopharyngeal carcinoma cases are not frequently encountered in our environment. Local stages are treated with radiotherapy. For advanced local stages, the association of chemotherapy with radiotherapy improves the rates of survival. In the case of metastatic disease stages, treatment requires platinum-based chemother... | ['Algorithms', 'Carcinoma', 'Humans', 'Monitoring, Physiologic', 'Nasopharyngeal Carcinoma', 'Nasopharyngeal Neoplasms', 'Neoplasm Metastasis', 'Neoplasm Staging', 'Recurrence'] | 23,982,852 | [['G17.035', 'L01.224.050'], ['C04.557.470.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.520'], ['C04.557.470.200.623', 'C04.588.443.665.710.650.500', 'C07.550.350.650.500', 'C07.550.745.650.500', 'C09.647.710.650.500', 'C09.775.350.650.500', 'C09.775.549.650.500'], ['C04.588.443.665.710.650', 'C07.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[A case with mild subdural hematoma presenting with a transient cluster of convulsions--problems concerning differentiation from benign infantile convulsion and benign complex partial epilepsies in infancy]. | A 1-month-old girl showed frequent partial seizures of sudden onset. Continuous spikes were observed in left central area during the ictal period, although interictal EEG showed neither epileptiform discharges nor focal signs. Optimal seizures control was obtained with intravenous administration of diazepam and subsequ... | ['Acute Disease', 'Diagnosis, Differential', 'Epilepsy, Benign Neonatal', 'Epilepsy, Complex Partial', 'Female', 'Hematoma, Subdural', 'Humans', 'Infant', 'Magnetic Resonance Imaging', 'Tomography, X-Ray Computed'] | 10,916,373 | [['C23.550.291.125'], ['E01.171'], ['C10.228.140.490.370', 'C16.614.258'], ['C10.228.140.490.360.260'], ['C10.228.140.300.535.450.400', 'C10.900.300.837.600', 'C14.907.253.573.400.450', 'C23.550.414.838.700', 'C23.550.414.913.700', 'C26.915.300.490.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703']... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Race, resistance, and restructuring: emerging skills in the new social services. | Since the introduction of the first neoliberal budgets in the mid-1980s, Canadian social service workers have had ample reason to resist changes in their work lives. Drawing on literature as well as on themes emerging from an intentionally diverse subset of data collected as part of a multiyear study, this article expl... | ['Adult', 'Career Choice', 'Ethnic Groups', 'Female', 'Humans', 'Male', 'Middle Aged', 'Social Work'] | 18,595,446 | [['M01.060.116'], ['F02.463.785.373.346.400'], ['M01.686.754', 'N01.224.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I01.880.792', 'N02.421.849']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
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