Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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FTIR spectroscopic evidence for the involvement of an acidic residue in quinone binding in cytochrome bd from Escherichia coli. | In this work, FTIR difference spectroscopy is used to search for possible binding partners and protonable groups involved in the binding of the quinol to cytochrome bd from Escherichia coli. In addition, the electrochemically induced FTIR difference spectra are compared for preparations of the enzyme isolated from cell... | ['Aerobiosis', 'Binding Sites', 'Cytochrome b Group', 'Cytochromes', 'Electrochemistry', 'Electron Transport Chain Complex Proteins', 'Escherichia coli', 'Escherichia coli Proteins', 'Oxidation-Reduction', 'Oxidoreductases', 'Protein Conformation', 'Quinones', 'Spectroscopy, Fourier Transform Infrared'] | 11,926,823 | [['G02.111.017', 'G03.049'], ['G02.111.570.120'], ['D08.244.187', 'D12.776.422.220.187'], ['D08.244', 'D12.776.422.220'], ['H01.181.529.307'], ['D08.811.600.250', 'D12.776.543.277'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G02.700', 'G03.295.531'], ['D08.811.682'], ['G02.111.570.8... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Mapping the Literature on Nutritional Interventions in Cognitive Health: A Data-Driven Approach. | Manual review of the extensive literature covering nutrition-based lifestyle interventions to promote healthy cognitive ageing has proved educational, however, data-driven techniques can better account for the large size of the literature (tens of thousands of potentially relevant publications to date) and interdiscipl... | ['Cognition', 'Data Mining', 'Humans', 'Nutritional Status', 'Research Design'] | 30,586,933 | [['F02.463.188'], ['L01.313.500.750.280.199', 'L01.470.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.650.650', 'N01.224.425.525'], ['E05.581.500', 'H01.770.644.728']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Sphingosine Kinase-1 Involves the Inhibitory Action of HIF-1á by Chlorogenic Acid in Hypoxic DU145 Cells. | Hypoxia enhances cancer development in a solid tumor. Hypoxia-inducible factor-1 á (HIF-1á) is a transcription factor that is dominantly expressed under hypoxia in solid tumor cells and is a key factor that regulates tumor. HIF-1á regulates several target genes involved in many aspects of cancer progression, including ... | ['Cell Line, Tumor', 'Cell Proliferation', 'Chlorogenic Acid', 'Enzyme Activation', 'Glycogen Synthase Kinase 3 beta', 'Humans', 'Hypoxia', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Neovascularization, Pathologic', 'Phosphorylation', 'Phosphotransferases (Alcohol Group Acceptor)', 'Plant Extracts', 'Protein Stabili... | 28,165,392 | [['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D02.241.223.200.185', 'D02.241.223.268.220'], ['G02.111.263', 'G03.328'], ['D05.500.117.875.500', 'D08.811.913.696.620.682.700.429.500.500', 'D08.811.913.696.620.682.700.646.625.500', 'D12.644.360.300.500.500', 'D12.776.476.081.875.500',... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Five common functional polymorphisms in microRNAs (rs2910164, rs2292832, rs11614913, rs3746444, rs895819) and the susceptibility to breast cancer: evidence from 8361 cancer cases and 8504 controls. | OBJECTIVES: To evaluate the relationship between the five common polymorphisms in miRNAs (miR-146a rs2910164 G>C, miR-149 rs2292832 C>T, miR-196a2 rs11614913 C>T, miR-499 rs3746444 A>G and miR-27a rs895819 A>G), and breast cancer (BC) risk.METHODS: Meta-analyses were performed on 15 published studies involving 8, 361 B... | ['Asian Continental Ancestry Group', 'Breast Neoplasms', 'European Continental Ancestry Group', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'MicroRNAs', 'Polymorphism, Single Nucleotide', 'Risk'] | 25,483,824 | [['M01.686.508.200'], ['C04.588.180', 'C17.800.090.500'], ['M01.686.508.400'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['G05.365.795.598'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Immediate Enhancement of Nerve Function Using a Novel Axonal Fusion Device After Neurotmesis. | BACKGROUND: The management of peripheral nerve injuries remains a large challenge for plastic surgeons. With the inability to fuse axonal endings, results after microsurgical nerve repair have been inconsistent. Our current nerve repair strategies rely upon the slow and lengthy process of axonal regeneration (~1 mm/d).... | ['Animals', 'Axons', 'Disease Models, Animal', 'Drug Delivery Systems', 'Electromyography', 'Female', 'Immunohistochemistry', 'Male', 'Nerve Regeneration', 'Neurosurgical Procedures', 'Peripheral Nerve Injuries', 'Polyethylene Glycols', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', 'Recovery of Function', 'Sciat... | 29,053,522 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.319.300'], ['E01.370.405.255', 'E01.370.530.255'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Experimental evidence of frequency-dependent selection on group behaviour. | Evolutionary ecologists often seek to identify the mechanisms maintaining intraspecific variation. In social animals, whole groups can exhibit between-group differences in their collective traits. We examined whether negative frequency-dependent selection (that is, a rare-type advantage) could help to maintain between-... | ['Animals', 'Female', 'Phenotype', 'Predatory Behavior', 'Selection, Genetic', 'Social Behavior', 'Spiders', 'Starvation'] | 30,911,148 | [['B01.050'], ['G05.695'], ['F01.145.113.111.600', 'F01.145.113.252.520'], ['G05.783'], ['F01.145.813'], ['B01.050.500.131.166.803'], ['C18.654.521.750']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Forensic application of intrarenal aquaporin-2 expression for differential diagnosis between freshwater and saltwater drowning. | Aquaporins (AQPs) are a family of homologous water channel proteins. In this study, the expressions of AQP1, 2, and 4 were immunohistochemically examined in kidney samples to evaluate their forensic applicability to differentiate between freshwater drowning (FWD) and saltwater drowning (SWD). Kidney samples were obtain... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Aquaporin 2', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Diagnosis, Differential', 'Drowning', 'Female', 'Forensic Pathology', 'Fresh Water', 'Humans', 'Immunohistochemistry', 'Infant', 'Kidney', 'Male', 'Middle Aged', 'Seawater', 'Young Adult'] | 19,834,729 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.157.530.400.500.040.437', 'D12.776.543.550.450.730.040.437', 'D12.776.543.585.400.730.040.530'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['E01.171'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Comparison of SOM point densities based on different criteria. | Point densities of model (codebook) vectors in self-organizing maps (SOMs) are evaluated in this article. For a few one-dimensional SOMs with finite grid lengths and a given probability density function of the input, the numerically exact point densities have been computed. The point density derived from the SOM algori... | ['Algorithms', 'Neural Networks, Computer'] | 10,578,045 | [['G17.035', 'L01.224.050'], ['G17.485', 'L01.224.050.375.605']] | ['Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Protective effect of oxymatrine on chronic rat heart failure. | Oxymatrine is one of the alkaloids extracted from the Chinese herb Sophora japonica (Sophora flavescens Ait.) with anti-inflammatory, immune reaction inhibiting, antiviral, and hepatocyte and antihepatic fibrosis protective activities. However, the effect of oxymatrine on heart failure is not yet known. In this study, ... | ['Alkaloids', 'Animals', 'Anti-Arrhythmia Agents', 'Calcium', 'Calcium Channels, L-Type', 'Calcium Signaling', 'Chronic Disease', 'Heart Failure', 'Male', 'Mitochondria, Heart', 'Quinolizines', 'Rats', 'Rats, Sprague-Dawley', 'Ryanodine Receptor Calcium Release Channel', 'Sarcoplasmic Reticulum', 'Sarcoplasmic Reticulu... | 21,691,940 | [['D03.132'], ['B01.050'], ['D27.505.954.411.097'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.530.400.150.400', 'D12.776.543.550.450.150.400', 'D12.776.543.585.400.150.400'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['C23.550.291.500'], ['C14.280.434'], ['A11.284.430.214... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transdiaphragmatic repositioning of the heart in the setting of emergency laparotomy after blunt trauma. | Cardiac luxation after blunt trauma is a rare condition that carries a high mortality rate. We report a case of a left pericardial rupture with partial dislocation of the heart into the left pleural cavity and cardiac strangulation in a polytraumatized patient after a severe motor vehicle accident. This case is of spec... | ['Accidents, Traffic', 'Heart Injuries', 'Humans', 'Laparotomy', 'Male', 'Middle Aged', 'Multiple Trauma', 'Pericardium', 'Rupture', 'Thoracic Injuries', 'Wounds, Nonpenetrating'] | 19,857,442 | [['N06.850.135.392'], ['C26.891.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.406'], ['M01.060.116.630'], ['C26.640'], ['A07.541.795', 'A10.615.789.470'], ['C26.761'], ['C26.891'], ['C26.974']] | ['Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A novel approach to detect test-seeking behaviour in the blood donor population: making the invisible visible. | BACKGROUND AND OBJECTIVES: Individuals may donate blood in order to determine their infection status after exposure to an increased infection risk. Such test-seeking behaviour decreases transfusion safety. Instances of test seeking are difficult to substantiate as donors are unlikely to admit to such behaviour. However... | ['Adult', 'Behavior', 'Blood Donors', 'Female', 'HIV Infections', 'Hepatitis C', 'Humans', 'Male', 'Middle Aged', 'Motivation', 'Syphilis'] | 27,281,653 | [['M01.060.116'], ['F01.145'], ['M01.898.313'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Correlates of return to work for breast cancer survivors. | PURPOSE: To identify correlates of return to work for employed breast cancer survivors.PATIENTS AND METHODS: Patients included 416 employed women with newly diagnosed breast cancer identified from the Metropolitan Detroit Cancer Surveillance System. Patients were interviewed by telephone 12 and 18 months after diagnosi... | ['Adult', 'Age Factors', 'Breast Neoplasms', 'Confidence Intervals', 'Employment', 'Female', 'Humans', 'Illinois', 'Lifting', 'Logistic Models', 'Middle Aged', 'Multivariate Analysis', 'Odds Ratio', 'Prejudice', 'Risk Factors', 'Surveys and Questionnaires', 'Survivors', 'Time Factors'] | 16,421,415 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['N01.824.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.350.350', 'Z01.107.567.875.510.350'], ['G01.374.669'], ['E05.318.740.500.52... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Motive- and appearance awareness-based explanations for body (dis)satisfaction following exercise in daily life. | OBJECTIVE: Although exercise is typically found to improve body satisfaction, this effect may be reduced or even reversed for trait body-dissatisfied individuals. The reasons for this remain unclear. This study tested the possibility that these effects are due to appearance-related motives and/or increased appearance a... | ['Adolescent', 'Adult', 'Awareness', 'Body Image', 'Emotions', 'Exercise', 'Female', 'Humans', 'Motivation', 'Personal Satisfaction', 'Self Report', 'Young Adult'] | 30,039,516 | [['M01.060.057'], ['M01.060.116'], ['F02.463.188.150'], ['F01.752.747.792.110', 'F02.463.593.112'], ['F01.470'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['F01.145.677'], ['E05.318.308.980.500', 'N05.715.360.300.800.500', 'N06.850.520.308.9... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The incompatibility product of IncFII R plasmid NR1 controls gene expression in the plasmid replication region. | The incompatibility properties of IncFII R plasmid NR1 were compared with those of two of its copy number mutants, pRR12 and pRR21. pRR12 produced an altered incompatibility product and also had an altered incompatibility target site. The target site appeared to be located within the incompatibility gene, which is loca... | ['Bacteriophage lambda', 'DNA Replication', 'DNA Restriction Enzymes', 'DNA, Recombinant', 'Escherichia coli', 'Genes', 'Lysogeny', 'Mutation', 'Nucleic Acid Hybridization', 'Plasmids', 'beta-Galactosidase'] | 6,290,455 | [['B04.123.150.800.230', 'B04.123.205.230', 'B04.280.090.800.230'], ['G02.111.225', 'G05.226'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D13.444.308.460'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340'], ['G05.935.500', 'G06.920.877.500'], ['G... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chronic hypothermia following tuberculous meningitis. | A patient who developed chronic hypothermia following tuberculous meningitis is described. A central defect of thermoregulation was discovered, probably due to a discrete vascular lesion in the anterior hypothalmus. | ['Adult', 'Body Temperature Regulation', 'Chronic Disease', 'Circadian Rhythm', 'Epilepsy, Tonic-Clonic', 'Female', 'Humans', 'Hypothermia', 'Memory, Short-Term', 'Tuberculosis, Meningeal'] | 6,785,394 | [['M01.060.116'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['C23.550.291.500'], ['G07.180.562.190'], ['C10.228.140.490.375.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.119.565'], ['F02.463.425.540.407'], ['C01.150.252.223.500.937', 'C01.150.252.223.850.800', 'C01.150.252.410.040.552.846.5... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of a targeted cognitive-behavioral program for children with conduct problems--the SNAP Under 12 Outreach Project: service intensity, age and gender effects on short- and long-term outcomes. | This study tested the effectiveness of a multifaceted, cognitive-behavioral therapy (CBT) program for antisocial children--the SNAP Under 12 Outreach Project (ORP)--in relation to age, sex and indices of treatment intensity. Study participants were 80 clinic-referred children (59 boys and 21 girls) aged 6-11 years assi... | ['Age Factors', 'Antisocial Personality Disorder', 'Child', 'Cognitive Behavioral Therapy', 'Community-Institutional Relations', 'Conduct Disorder', 'Control Groups', 'Female', 'Humans', 'Juvenile Delinquency', 'Male', 'Personality Inventory', 'Probability', 'Program Evaluation', 'Sex Factors'] | 18,783,124 | [['N05.715.350.075', 'N06.850.490.250'], ['F03.675.050'], ['M01.060.406'], ['F04.754.137.350'], ['N04.452.822.210'], ['F03.625.094.300'], ['E05.318.370.074', 'E05.581.500.149'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.735.479'], ['F04.711.647.513'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Inconsistencies in quality of life data collection in clinical trials: a potential source of bias? Interviews with research nurses and trialists. | BACKGROUND: Patient-reported outcomes (PROs), such as health-related quality of life (HRQL) are increasingly used to evaluate treatment effectiveness in clinical trials, are valued by patients, and may inform important decisions in the clinical setting. It is of concern, therefore, that preliminary evidence, gained fro... | ['Bias', 'Clinical Trials as Topic', 'Data Collection', 'Humans', 'Qualitative Research', 'Quality of Life', 'Research Design', 'Research Personnel', 'Surveys and Questionnaires'] | 24,124,580 | [['N05.715.350.150', 'N06.850.490.500'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644.241.850'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Clinical Characteristics of Epidemic Myalgia Associated with Human Parechovirus Type 3 during the Summer of 2019. | Objective Epidemic myalgia associated with human parechovirus type 3 (EM-HPeV3) is characterized by severe muscle pain and weakness on the limbs and trunk with a fever. No outbreak of EM-HPeV3 has been reported since 2016, and its clinical characteristics have not been sufficiently clarified. We herein report a series ... | ['Adult', 'Disease Outbreaks', 'Female', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Myalgia', 'Picornaviridae Infections', 'Pleurodynia, Epidemic', 'Retrospective Studies'] | 32,296,005 | [['M01.060.116'], ['N06.850.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['C05.651.542', 'C10.668.491.525', 'C23.888.592.612.547.249', 'F02.830.816.353.500', 'G11.561.790.353.500'], ['C01.925.782.687'], ['C01.925.782.687.359.213.737'], ['E05.318.372.50... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Increasing the dose, evaluating compliance, revising the diagnosis. Prescriptions for apparently resistant processes in the esophagus]. | One of the most common reasons for failed treatment of esophageal diseases is inadequate medication dosage. This applies in particular to gastro-esophageal reflux disease (GERD). In many cases, however, the adoption of unrealistic therapeutic aims or inappropriate target criteria may play a role. Last, but not least, a... | ['Antacids', 'Anti-Ulcer Agents', 'Diagnostic Errors', 'Dose-Response Relationship, Drug', 'Esophagitis, Peptic', 'Gastroesophageal Reflux', 'Humans', 'Patient Compliance', 'Recurrence', 'Treatment Failure'] | 11,026,221 | [['D27.505.519.170', 'D27.505.954.483.080'], ['D27.505.954.483.203'], ['E01.354', 'N02.421.450.280'], ['G07.690.773.875', 'G07.690.936.500'], ['C06.405.117.620.420', 'C06.405.205.663.420', 'C06.405.469.275.800.523', 'C06.405.748.586.524'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Freeze-fracture study of muscle plasmalemma in normal and dystrophic chickens. | We compared the freeze-fracture morphology of the plasmalemma of the pectoralis major muscle taken from normal and dystrophic chickens at adult, embryonic, and early posthatching stages. Developmental changes were more conspicuous in surface caveolae than in intramembranous particles. The most striking differences betw... | ['Animals', 'Chickens', 'Freeze Fracturing', 'Muscular Dystrophy, Animal', 'Sarcolemma'] | 503,105 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predictive value of clinical history compared with urodynamic study in 1,179 women. | OBJECTIVE: to determine the positive predictive value of clinical history in comparison with urodynamic study for the diagnosis of urinary incontinence.METHODS: retrospective analysis comparing clinical history and urodynamic evaluation of 1,179 women with urinary incontinence. The urodynamic study was considered the g... | ['Female', 'Humans', 'Medical Records', 'Middle Aged', 'Predictive Value of Tests', 'Reference Values', 'Reproducibility of Results', 'Retrospective Studies', 'Urinary Bladder, Overactive', 'Urinary Incontinence', 'Urodynamics'] | 27,008,494 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.940.968', 'N04.452.859.564', 'N05.715.360.300.715.500', 'N06.850.520.308.940.968'], ['M01.060.116.630'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E05.978.810'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Pollution Characteristics and Sources of Carbonaceous Aerosol in PM2.5 During Winter in Guanzhong Area]. | To study the characteristics and sources of carbonaceous aerosol in PM2.5 during winter in Guanzhong area, PM2.5 samples were collected from December 2012 to February 2013 in Xi'an, Baoji, Weinan and Qinling, and then organic carbon (OC) and elemental carbon (EC) were analyzed following the thermal/optical reflection p... | ['Aerosols', 'Air Pollutants', 'Biomass', 'Carbon', 'China', 'Coal', 'Environmental Monitoring', 'Gasoline', 'Particle Size', 'Particulate Matter', 'Seasons'] | 27,363,127 | [['D20.280.055', 'D26.255.165.055'], ['D27.888.284.101'], ['G16.500.275.157.100', 'N06.230.124.100'], ['D01.268.150'], ['Z01.252.474.164'], ['D20.345.108', 'N06.230.132.258.108'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D20.345.630.540', 'N06.230.132.258.630.540'], ['G02.712'], ['D20.633'], ['G01.910.645.661', 'G... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Reproducibility of serum sex steroid assays in men by RIA and mass spectrometry. | There is an increasing trend to apply gas chromatography combined with mass spectrometry (GC-MS) or liquid chromatography tandem mass spectrometry (LC-MS/MS) assay methods to large-scale epidemiologic studies for the measurement of serum sex steroids. These methods are generally considered the gold standard for sex ste... | ['Aged', 'Algorithms', 'Androstenedione', 'Gas Chromatography-Mass Spectrometry', 'Gonadal Steroid Hormones', 'Humans', 'Male', 'Middle Aged', 'Radioimmunoassay', 'Reproducibility of Results', 'Testosterone'] | 17,507,629 | [['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['D04.210.500.054.079.329', 'D04.210.500.578.502.112', 'D06.472.040.502.112', 'D06.472.334.851.968.875'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D06.472.334.851'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.384.700', 'E05.478.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Changes in mouse mammary epithelial cell size during mammary gland development. | The average volume and size distribution of mouse mammary epithelial cells (MMEC) at different stages of functional activity of the mammary gland have been estimated. During early pregnancy, the mean MMEC volume begins to enlarge, resulting in a 21-fold cell volume increase by late lactation (Day 18). Progressive incre... | ['Animals', 'Cell Differentiation', 'Epithelial Cells', 'Female', 'Lactation', 'Mammary Glands, Animal', 'Mice', 'Pregnancy'] | 884,741 | [['B01.050'], ['G04.152'], ['A11.436'], ['G08.686.523', 'G08.686.702.500'], ['A10.336.482', 'A13.589'], ['B01.050.150.900.649.313.992.635.505.500'], ['G08.686.784.769']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Differential roles of the basolateral amygdala and nucleus basalis magnocellularis during post-reactivation contextual fear conditioning reconsolidation in rats. | The roles of the basolateral amygdala and nucleus basalis magnocellularis in fear conditioning reconsolidation were investigated by means of tetrodotoxin bilateral inactivation performed 96 h after conditioning, immediately after reactivation training. Footshocks of 1.2 mA intensity were employed to induce the generali... | ['Acoustic Stimulation', 'Amnesia', 'Amygdala', 'Analysis of Variance', 'Animals', 'Basal Nucleus of Meynert', 'Brain Mapping', 'Conditioning, Psychological', 'Fear', 'Male', 'Memory', 'Motor Activity', 'Rats', 'Rats, Wistar'] | 18,691,662 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['C10.597.606.525.100', 'C23.888.592.604.529.100', 'F01.700.625.100', 'F03.615.200'], ['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A08.186.211.200.885.287.249.880.100'], ['E01... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cardiac MR elastography for quantitative assessment of elevated myocardial stiffness in cardiac amyloidosis. | PURPOSE: To evaluate if cardiac magnetic resonance elastography (MRE) can measure increased stiffness in patients with cardiac amyloidosis. Myocardial tissue stiffness plays an important role in cardiac function. A noninvasive quantitative imaging technique capable of measuring myocardial stiffness could aid in disease... | ['Aged', 'Aged, 80 and over', 'Amyloidosis', 'Case-Control Studies', 'Contrast Media', 'Echocardiography', 'Elastic Modulus', 'Elasticity Imaging Techniques', 'Female', 'Heart', 'Heart Ventricles', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Myocardium', 'Patie... | 28,236,336 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C18.452.845.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D27.505.259.500', 'D27.720.259'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['G01.374.590.605'], ['E01.370.350.850.270'], ['A07.541'], ['A07.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Preoperative RAS mutational analysis is of great value in predicting follicular variant of papillary thyroid carcinoma. | Follicular variant of papillary thyroid carcinoma (FVPTC), particularly the encapsulated subtype, often causes a diagnostic dilemma. We reconfirmed the molecular profiles in a large number of FVPTCs and investigated the efficacy of the preoperative mutational analysis in indeterminate thyroid nodules. BRAF V600E/K601E ... | ['Adult', 'Carcinoma', 'Carcinoma, Papillary', 'DNA Mutational Analysis', 'Female', 'Humans', 'Male', 'Middle Aged', 'Preoperative Period', 'Proto-Oncogene Proteins B-raf', 'Proto-Oncogene Proteins p21(ras)', 'Thyroid Cancer, Papillary', 'Thyroid Neoplasms', 'Thyroid Nodule'] | 25,648,502 | [['M01.060.116'], ['C04.557.470.200'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['E05.393.760.700.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.614.937', 'N02.421.585.753.937'], ['D08.811.913.696.620.682.700.559.842.374', 'D12.644.360.400.842.374', 'D12.776.476.400.842.437', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Self-association and DNA binding properties of the human topoisomerase IIA alpha2HTH module. | The eukaryotic topoisomerase II is an ubiquitous nuclear enzyme involved in vital cellular functions. It is also the target for some of the most active anticancer drugs. In the various crystal structures of yeast topoisomerase II, the 701-748 segment homologous to the human topoisomerase II alpha 724-771 segment folds ... | ['Amino Acid Sequence', 'Animals', 'Antigens, Neoplasm', 'DNA', 'DNA Topoisomerases, Type II', 'DNA-Binding Proteins', 'Dimerization', 'Dose-Response Relationship, Drug', 'Helix-Turn-Helix Motifs', 'Humans', 'Models, Molecular', 'Molecular Sequence Data', 'Peptide Fragments', 'Protein Binding', 'Protein Conformation', ... | 16,213,649 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D23.050.285'], ['D13.444.308'], ['D08.811.399.403.741'], ['D12.776.260'], ['G02.206', 'G03.230'], ['G07.690.773.875', 'G07.690.936.500'], ['G02.111.570.820.709.275.500.360.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595'], ['L01.453.245.6... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Validation of Submaximal Step Tests and the 6-Min Walk Test for Predicting Maximal Oxygen Consumption in Young and Healthy Participants. | Background: This study aimed to test the validity of three different submaximal tests (i.e., 3-min step test with 20.3-cm step box height (3MST20), 3-min step test with 30-cm step box height (3MST30), and 6-min walk test (6MWT)) in estimating maximal oxygen consumption (VO2max) in young and healthy individuals. Methods... | ['Adult', 'Exercise Test', 'Female', 'Healthy Volunteers', 'Humans', 'Male', 'Oxygen Consumption', 'Republic of Korea', 'Time Factors', 'Walk Test', 'Walking', 'Young Adult'] | 31,816,834 | [['M01.060.116'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['M01.774.500', 'M01.955.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.680'], ['Z01.252.474.557.750'], ['G01.910.857'], ['E01.370.370.380.250.500'], ['G11.427.410.568.900', 'G11.427.410.698.277.937', 'I03.350.937', 'I03.450... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Tobacco MYC2 regulates jasmonate-inducible nicotine biosynthesis genes directly and by way of the NIC2-locus ERF genes. | In Arabidopsis, the MYC2-family basic helix-loop-helix transcription factors mediate transcriptional regulation of jasmonate-responsive genes, and their transcriptional activities are suppressed by physical interactions with jasmonate-ZIM domain (JAZ) proteins. Jasmonate-inducible nicotine formation in Nicotiana plants... | ['Amino Acid Substitution', 'Basic Helix-Loop-Helix Leucine Zipper Transcription Factors', 'Binding Sites', 'Cells, Cultured', 'Cyclopentanes', 'G-Box Binding Factors', 'Gene Expression Profiling', 'Gene Expression Regulation, Plant', 'Gene Knockdown Techniques', 'Genes, Plant', 'Nicotine', 'Oxylipins', 'Phylogeny', 'P... | 21,576,194 | [['E05.393.420.601.035', 'G05.558.109'], ['D12.776.260.103.500', 'D12.776.260.108.092', 'D12.776.930.125.500', 'D12.776.930.127.092'], ['G02.111.570.120'], ['A11.251'], ['D02.455.426.392.368.450'], ['D12.776.260.254', 'D12.776.765.365', 'D12.776.930.313'], ['E05.393.332'], ['G05.308.375'], ['E05.393.335.500'], ['G05.36... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Information Science [L]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
High blood pressure in school children: prevalence and risk factors. | BACKGROUND: The purpose of this study was to determine the prevalence of high blood pressure (HBP) and associated risk factors in school children 8 to 13 years of age.METHODS: Elementary school children (n = 1,066) were examined. Associations between HBP, body mass index (BMI), gender, ethnicity, and acanthosis nigrica... | ['Adolescent', 'Child', 'Female', 'Humans', 'Hypertension', 'Male', 'Prevalence', 'Risk Factors'] | 17,109,750 | [['M01.060.057'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', ... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Long term mortality after a single treatment course with X-rays in patients treated for ankylosing spondylitis. | Mortality up to 1 January 1983 has been studied in 14,106 patients with ankylosing spondylitis given a single course of X-ray treatment during 1935-54. For neoplasms other than leukaemia or colon cancer, mortality was 28% greater than that of members of the general population of England and Wales, and this increase is ... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Colonic Neoplasms', 'Female', 'Follow-Up Studies', 'Humans', 'Leukemia, Radiation-Induced', 'Male', 'Middle Aged', 'Neoplasms, Radiation-Induced', 'Sex Factors', 'Spondylitis, Ankylosing', 'Time Factors', 'United Kingdom'] | 3,814,487 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Insoluble and soluble roasted walnut proteins retain antibody reactivity. | Thermal processing techniques commonly used during food production have the potential to impact food allergens by inducing physical and/or chemical changes to the proteins. English walnuts (Juglans regia) are among the most commonly allergenic tree nuts, but little information is available regarding how walnut allergen... | ['Allergens', 'Food Hypersensitivity', 'Immunoglobulin E', 'Juglans', 'Nuts', 'Plant Proteins'] | 26,471,647 | [['D23.050.063'], ['C20.543.480.370'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.715.548.114.619.312'], ['B01.650.940.800.575.912.250.859.750.500.500'], ['A18.024.500.500', 'G07.203.300.700', 'J02.500.700'], ['D12.776.765']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Primary umbilical endometriosis--a rare variant of cutaneous endometriosis. | A case of primary umbilical endometriosis is being reported here, who presented with a dark brown nodule on the umbilicus with black pigmentation around it for the last seven months, associated with cyclical pain and bleeding from the nodule. Wide local excision of the nodule, laparoscopic tubal ligation and visualizat... | ['Adult', 'Biopsy, Needle', 'Diagnosis, Differential', 'Endometriosis', 'Female', 'Follow-Up Studies', 'Humans', 'Immunohistochemistry', 'Laparoscopy', 'Risk Assessment', 'Skin Diseases', 'Sterilization, Tubal', 'Treatment Outcome', 'Umbilicus'] | 12,689,538 | [['M01.060.116'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['E01.171'], ['C13.351.500.163'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.75... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
A molecular scanner to automate proteomic research and to display proteome images. | Identification and characterization of all proteins expressed by a genome in biological samples represent major challenges in proteomics. Today's commonly used high-throughput approaches combine two-dimensional electrophoresis (2-DE) with peptide mass fingerprinting (PMF) analysis. Although automation is often possible... | ['Automation', 'Blood Proteins', 'Electrophoresis, Gel, Two-Dimensional', 'Electrophoresis, Polyacrylamide Gel', 'Humans', 'Image Processing, Computer-Assisted', 'Peptide Mapping', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Trypsin Inhibitor, Kunitz Soybean'] | 10,565,287 | [['J01.897.104'], ['D12.776.124'], ['E05.196.401.250', 'E05.301.300.230'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E05.196.181.400.454.720', 'E05.196.401.319.720', 'E05.196.700', 'E05.393.760.705.685'], ['E05.196.566.755'], ['D12.776.765.741.750']] | ['Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Elimination of bacteria on different implant surfaces through photosensitization and soft laser. An in vitro study. | Microbiologic examinations of implants have shown that certain microorganisms described as periodontal pathogens may have an influence on the development and the progression of peri-implant disease. This experimental study aimed to examine the bactericidal effect of irradiation with a soft laser on bacteria associated ... | ['Aggregatibacter actinomycetemcomitans', 'Bacteria', 'Bacterial Adhesion', 'Bacterial Infections', 'Colony Count, Microbial', 'Implants, Experimental', 'Lasers', 'Microscopy, Electron, Scanning', 'Photosensitizing Agents', 'Porphyromonas gingivalis', 'Prevotella intermedia', 'Titanium', 'Tolonium Chloride'] | 9,586,470 | [['B03.440.450.600.224.500', 'B03.660.250.550.170.500'], ['B03'], ['G06.099.050'], ['C01.150.252'], ['E01.370.225.875.220', 'E05.200.875.220'], ['E07.695.340'], ['E07.632.490', 'E07.710.520'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D27.505.954.444.600', 'D27.505.954.600.710'], ['B03.440.080.094.625.515', 'B0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multinucleate osteoclasts in medaka as evidence of active bone remodeling. | Putative sites of bone resorption in the acellular bony skeleton of the medaka fish (Oryzias latipes) were investigated primarily by RNA in situ hybridization and histological analysis. Numerous cells that displayed intense enzymatic activity of tartrate-resistant acid phosphatase (TRAP), the main marker of osteoclasts... | ['Acid Phosphatase', 'Alkaline Phosphatase', 'Amino Acid Sequence', 'Animals', 'Bone Remodeling', 'Cathepsin K', 'Cathepsins', 'Cell Differentiation', 'Cell Nucleus', 'Isoenzymes', 'Molecular Sequence Data', 'Oryzias', 'Osteoblasts', 'Osteoclasts', 'Skeleton', 'Tartrate-Resistant Acid Phosphatase', 'Vacuolar Proton-Tra... | 17,049,327 | [['D08.811.277.352.650.025'], ['D08.811.277.352.650.035'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G11.427.213', 'G16.762.150'], ['D08.811.277.656.224.405', 'D08.811.277.656.262.500.156', 'D08.811.277.656.300.200.156'], ['D08.811.277.656.224'], ['G04.152'], ['A11.284.430.106', 'A11.284.430.214.190.87... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Laparoscopic simultaneous treatment of peripelvic renal cysts and stones: case series. | INTRODUCTION: Renal multiple peripelvic cysts are often symptomatic. Obstruction of renal hilum and the collecting system leads to hydronephrosis and could promote formation of stones. Managing both entities at the same time needs a new approach to minimize complications and improve success rates. We report for the fir... | ['Aged', 'Demography', 'Female', 'Humans', 'Kidney Calculi', 'Kidney Diseases, Cystic', 'Laparoscopy', 'Male', 'Middle Aged', 'Pelvis', 'Preoperative Care', 'Tomography, X-Ray Computed'] | 19,619,068 | [['M01.060.116.100'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.600.500', 'C12.777.967.249.500', 'C12.777.967.500.503', 'C13.351.968.419.600.500', 'C13.351.968.967.249.500', 'C13.351.968.967.500.503', 'C23.300.175.850.550'], ['C12.777.419.403', 'C13.351.96... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Inhibition of stem cell factor-induced proliferation of primitive murine hematopoietic progenitor cells signaled through the 75-kilodalton tumor necrosis factor receptor. Regulation of c-kit and p53 expression. | TNF-alpha is a pleiotropic cytokine with stimulatory as well as inhibitory effects on hematopoiesis. We have previously demonstrated that TNF-alpha directly inhibits CSF-induced proliferation of primitive murine lineage-negative bone marrow progenitors (Lin-) and stem cell antigen-1 hematopoietic progenitors through th... | ['Animals', 'Bone Marrow Cells', 'Cell Division', 'Gene Expression Regulation', 'Hematopoiesis', 'Hematopoietic Cell Growth Factors', 'In Vitro Techniques', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred C57BL', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-kit', 'RNA, Messenger', 'Receptor Protein-Tyrosine Kin... | 7,535,812 | [['B01.050'], ['A11.148', 'A15.378.316'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G05.308'], ['G04.152.825', 'G09.188.343'], ['D12.644.276.374.410', 'D12.776.467.374.410', 'D23.529.374.410'], ['E05.481'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
C-reactive protein as a predictor of hypertension in the Hong Kong Cardiovascular Risk Factor Prevalence Study (CRISPS) cohort. | Inflammation contributes to the development of hypertension. Whether C-reactive protein (CRP) has a causal role in hypertension remains unknown. We studied the relationship between circulating CRP levels and hypertension. The role of single-nucleotide polymorphisms (SNPs) in the CRP gene as determinants of its plasma l... | ['Adult', 'Aged', 'Biomarkers', 'C-Reactive Protein', 'Female', 'Genetic Predisposition to Disease', 'Haplotypes', 'Hong Kong', 'Humans', 'Hypertension', 'Inflammation', 'Inflammation Mediators', 'Linkage Disequilibrium', 'Logistic Models', 'Male', 'Middle Aged', 'Odds Ratio', 'Polymorphism, Single Nucleotide', 'Predic... | 21,270,838 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380.360'], ['Z01.252.474.164.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C23.550.470'], ['D23.469'], ['G05.348.500'], ['E05.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Neuroaxonal Dystrophy and Cavitating Leukoencephalopathy of Chihuahua Dogs. | A novel form of neuroaxonal dystrophy is described in 3 Chihuahua pups, 2 of which were from the same litter. It was characterized not only by accumulation of numerous and widely distributed axonal swellings (spheroids) but also by a severe cavitating leukoencephalopathy. The dogs presented with progressive neurologica... | ['Animals', 'Atrophy', 'Brain', 'Dog Diseases', 'Dogs', 'Female', 'Leukoencephalopathies', 'Magnetic Resonance Imaging', 'Male', 'Neuroaxonal Dystrophies'] | 28,578,630 | [['B01.050'], ['C23.300.070'], ['A08.186.211'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['C10.228.140.695'], ['E01.370.350.825.500'], ['C10.228.140.744']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Music interventions and group participation skills of preschoolers with visual impairments: raising questions about music, arousal, and attention. | The purposes of this pilot study were two-fold: First, to document and compare attentive behavior during music and play-based group instructional sessions and second, to document and compare 4 group participation behaviors during music and play-based sessions. The 4 group participation behaviors included facing a centr... | ['Arousal', 'Attention', 'Child', 'Child Behavior', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Music Therapy', 'Pilot Projects', 'Play and Playthings', 'Psychotherapy, Group', 'Social Behavior', 'Time Factors', 'Treatment Outcome', 'Vision Disorders', 'Visually Impaired Persons'] | 15,015,909 | [['F02.830.104', 'G11.561.035'], ['F02.830.104.214'], ['M01.060.406'], ['F01.145.179'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.888.500', 'E02.760.169.063.500.440', 'E02.831.440', 'F04.754.549'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Phase I-II RTOG study (99-06) of patients with muscle-invasive bladder cancer undergoing transurethral surgery, paclitaxel, cisplatin, and twice-daily radiotherapy followed by selective bladder preservation or radical cystectomy and adjuvant chemotherapy. | OBJECTIVES: To evaluate the safety, tolerance, protocol completion rate, tumor response rate, and patient survival of chemoradiotherapy for patients with muscle-invasive operable bladder cancer.METHODS: After transurethral resection of the tumor in patients with Stage T2-T4a bladder cancer, twice-daily radiotherapy wit... | ['Antineoplastic Agents', 'Chemotherapy, Adjuvant', 'Cisplatin', 'Combined Modality Therapy', 'Cystectomy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Muscle, Smooth', 'Neoplasm Invasiveness', 'Paclitaxel', 'Urethra', 'Urinary Bladder Neoplasms', 'Urologic Surgical Procedures'] | 19,100,600 | [['D27.505.954.248'], ['E02.186.170', 'E02.319.170'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E02.186'], ['E04.950.774.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.570', 'A10.690.467'], ['C04.697.645', 'C23.550.727.645'], ['D02.455.426.392.368.242.888.777', 'D02.455.84... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A double-split gluteus maximus muscle flap for reconstruction of the rectal sphincter. | A double-split gluteus maximus muscle flap has been described as a method for reconstructing difficult cases of rectal sphincter disruption secondary to trauma. Anatomic considerations and three case reports are documented. All three patients have derived nearly complete rectal continence after this procedure. The use ... | ['Adult', 'Buttocks', 'Female', 'Humans', 'Male', 'Methods', 'Muscles', 'Rectum', 'Surgical Flaps'] | 3,966,108 | [['M01.060.116'], ['A01.378.610.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['A02.633', 'A10.690'], ['A03.556.124.526.767', 'A03.556.249.249.767'], ['A10.850.710', 'E07.862.710']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Experimental H1N1pdm09 infection in pigs mimics human seasonal influenza infections. | Pigs are anatomically, genetically and physiologically comparable to humans and represent a natural host for influenza A virus (IAV) infections. Thus, pigs may represent a relevant biomedical model for human IAV infections. We set out to investigate the systemic as well as the local immune response in pigs upon two sub... | ['Animals', 'Disease Models, Animal', 'Humans', 'Influenza A Virus, H1N1 Subtype', 'Influenza, Human', 'Lung', 'Orthomyxoviridae Infections', 'Seasons', 'Swine', 'Swine Diseases', 'T-Lymphocytes, Cytotoxic'] | 31,539,406 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400.214'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['A04.411'], ['C01.925.782.620'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['B01.050.150.900... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Acidolysis between triolein and short-chain fatty acid by lipase in organic solvents. | Ten kinds of lipases were examined as biocatalysts for the incorporation of short-chain fatty acids (acetic, propionic, and butyric acids) into triolein in order to produce one kind of reduced-calorie structured lipids. Trans-esterification (acidolysis) was successfully done in n-hexane by several microbial lipases. Am... | ['Aspergillus oryzae', 'Catalysis', 'Chromatography, Thin Layer', 'Fatty Acids', 'Hydrogen-Ion Concentration', 'Hydrolysis', 'Kinetics', 'Lipase', 'Lipid Metabolism', 'Lipids', 'Organic Chemicals', 'Solvents', 'Substrate Specificity', 'Triglycerides', 'Triolein'] | 16,041,127 | [['B01.300.381.081.500'], ['G02.130'], ['E05.196.181.400.537'], ['D10.251'], ['G02.300'], ['G02.380'], ['G01.374.661', 'G02.111.490'], ['D08.811.277.352.100.400'], ['G03.458'], ['D10'], ['D02'], ['D27.720.844'], ['G02.111.835'], ['D10.351.801'], ['D10.212.507.850', 'D10.351.801.801']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bone death in hip fracture in the elderly. | We examined femoral head bone from 50 cadavers and from 21 patients who had suffered pathologic fracture of the femoral neck. We used a histochemical technique for lactate dehydrogenase (LDH) activity to demonstrate osteocyte viability. The femoral heads were removed within 36 hours of death or fracture, as LDH activit... | ['Aged', 'Aged, 80 and over', 'Cell Survival', 'Female', 'Femoral Neck Fractures', 'Femur Head', 'Humans', 'Male', 'Osteocytes'] | 2,257,519 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G04.346'], ['C26.404.061.425.500', 'C26.531.750.500', 'C26.558.276.425.500'], ['A02.835.232.043.150.343'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.629.500']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rapid screening for S-adenosylmethionine-dependent methylation products by enzyme-transferred isotope patterns analysis. | We report here an isotopic labeling and mass spectrometric method to rapidly identify S-adenosylmethionine (AdoMet)-dependent methylation products. In the presence of CH(3)- and CD(3)-labeled AdoMet, a methyl transfer product appears as a doublet separated by 3 Da in a mass spectrum, while other compounds show their no... | ['Deuterium', 'Escherichia coli', 'Humans', 'Isotope Labeling', 'Methylation', 'Methyltransferases', 'S-Adenosylmethionine', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization'] | 14,755,618 | [['D01.268.406.500', 'D01.362.340.500', 'D01.496.289'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.522'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['D08.811.913.555.500'], ['D02.886.030.676.180', 'D03.633.100.759.590.138.264', 'D12.125.16... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Improvement of the H5N1 influenza virus vaccine strain to decrease the pathogenicity in chicken embryos. | The avian influenza vaccine strain A/duck/Hokkaido/Vac-1/2004 (H5N1) (Vac-1) was found to be pathogenic in chicken embryos (CEs). In order to decrease the pathogenicity of Vac-1 in CEs, a series of reassortant viruses was generated between Vac-1 and A/Puerto Rico/8/1934 (H1N1) (PR8), and their pathogenicity and growth ... | ['Allantois', 'Animals', 'Chick Embryo', 'Influenza A Virus, H1N1 Subtype', 'Influenza A Virus, H5N1 Subtype', 'Influenza Vaccines', 'Reassortant Viruses', 'Viral Load'] | 21,203,786 | [['A10.615.284.147', 'A16.254.750.147'], ['B01.050'], ['A13.350.150', 'A16.331.200'], ['B04.820.480.968.405.400.214'], ['B04.820.480.968.405.400.500'], ['D20.215.894.899.302'], ['B04.800'], ['E01.370.225.875.950', 'E05.200.875.950', 'G06.920.850']] | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Speaking fundamental frequency characteristics of white, African American, and Hispanic kindergartners. | Speech samples from groups of White, African American, and Hispanic kindergarten-age children were compared on measures of mean speaking fundamental frequency (F(zero)), maximum and minimum speaking F(zero), pitch sigma, and speaking range (in semitones). Results indicate that there are significant differences between ... | ['African Americans', 'Anthropometry', 'Child', 'Cross-Cultural Comparison', 'European Continental Ancestry Group', 'Female', 'Hispanic Americans', 'Humans', 'Male', 'Speech', 'Verbal Behavior'] | 8,783,135 | [['M01.686.508.100.100', 'M01.686.754.100'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['M01.060.406'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['M01.686.508.400'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.908.677', 'G11.561.812', 'L01.559.423.676'], ['F01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
A generalized staphylococcal scalded skin-like disease in lambs. | An idiopathic disease involving skin and kidneys was seen in two Merino lambs from the same herd. A generalized skin exfoliation in association with acute renal failure were the most prominent clinical features. The condition resembled staphylococcal scalded-skin syndrome of man, and pure cultures of Staphylococcus aur... | ['Acute Kidney Injury', 'Animals', 'Biopsy', 'Fatal Outcome', 'Kidney', 'Sheep', 'Sheep Diseases', 'Skin', 'Staphylococcal Scalded Skin Syndrome', 'Staphylococcus aureus'] | 10,605,373 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['B01.050'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The renal artery is involved in Chinese Takayasu's arteritis patients. | Takayasu's arteritis is a rare systemic vasculitis mainly affecting the aorta and its major branches. Previous studies have suggested that almost half of the Asian Takayasu's patients have renal artery involvement. However, due to the rarity of the disease, little is known about renal artery involvement in Chinese Taka... | ['Adolescent', 'Adult', 'China', 'Female', 'Glomerular Filtration Rate', 'Heart Failure', 'Humans', 'Hypertension, Pulmonary', 'Kidney Failure, Chronic', 'Male', 'Prevalence', 'Prognosis', 'Renal Artery', 'Renal Artery Obstruction', 'Retrospective Studies', 'Risk Factors', 'Severity of Illness Index', 'Takayasu Arterit... | 28,863,945 | [['M01.060.057'], ['M01.060.116'], ['Z01.252.474.164'], ['E01.370.390.400.300', 'G08.852.357'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.50... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Dynamic excitatory and inhibitory gain modulation can produce flexible, robust and optimal decision-making. | Behavioural and neurophysiological studies in primates have increasingly shown the involvement of urgency signals during the temporal integration of sensory evidence in perceptual decision-making. Neuronal correlates of such signals have been found in the parietal cortex, and in separate studies, demonstrated attention... | ['Decision Making', 'Humans', 'Models, Theoretical', 'Reaction Time', 'Task Performance and Analysis'] | 23,825,935 | [['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Changes in oxidative metabolism of murine spleen following laser and superluminous diode (660-950 nm) irradiation: effects of cellular composition and radiation parameters. | Chemiluminescence (CL) of splenocytes of A/Sn mice was recorded after irradiation of the cells with various individual laser an superluminous diode probes at wavelengths from 660 to 950 nm (pulse repetition rates varying from 4 to 5,000 Hz) and at various doses. Laser radiation was found to increase or suppress the spo... | ['Aging', 'Animals', 'Cell Count', 'Dose-Response Relationship, Radiation', 'In Vitro Techniques', 'Kinetics', 'Lasers', 'Luminescent Measurements', 'Male', 'Mice', 'Oxygen', 'Spleen'] | 8,366,746 | [['G07.345.124'], ['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['E07.632.490', 'E07.710.520'], ['E05.196.712.516'], ['B01.050.150.900... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Microbiological decomposition of organic matter in the bottom sediments of Lithuanian lakes]. | The rates of the processes of bacterial sulfate reduction (SR) and decomposition of organic matter (D(total)) were studied in the bottom sediments (BS) of 14 lakes in Lithuanian national and regional parks in the summers of 1998-2002. Anaerobic processes accounted for an average of 92% of D(total) in the depressions of... | ['Anaerobiosis', 'Biodegradation, Environmental', 'Colony Count, Microbial', 'Ecosystem', 'Fresh Water', 'Geologic Sediments', 'Lithuania', 'Sulfates', 'Sulfur-Reducing Bacteria', 'Temperature'] | 16,758,875 | [['G02.111.062', 'G03.078'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['E01.370.225.875.220', 'E05.200.875.220'], ['G16.500.275.157', 'N06.230.124'], ['G16.500.275.280', 'N06.230.232'], ['G01.311.330', 'G16.500.320'], ['Z01.542.248.136.580'], ['D01.248.497.158.845', 'D01.875.800.800.850'], ['B03.900'], ['G01.906... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Alpha satellite DNA-repeat OwlAlp1 forms centromeres in Azara's owl monkey. | Centromeres play crucial roles in faithful chromosome segregation and genome integrity. In simian primates, centromeres possess tandem array of alpha satellite DNA (also referred to as alphoid DNA). Average sizes of alpha satellite repeat units vary between species, for example, 171 bp in human and 343-344 bp in many p... | ['Animals', 'Aotidae', 'Cells, Cultured', 'Centromere', 'Centromere Protein A', 'Chromatin Immunoprecipitation', 'DNA, Satellite', 'Heterochromatin', 'Histones', 'Humans'] | 31,095,817 | [['B01.050'], ['B01.050.150.900.649.313.988.400.600.037'], ['A11.251'], ['A11.284.430.106.279.345.190.160.165', 'G05.360.160.165'], ['D12.776.157.687.173', 'D12.776.260.123', 'D12.776.660.235.100', 'D12.776.660.720.173', 'D12.776.664.235.100', 'D23.050.422.031'], ['E05.393.170', 'E05.478.605.160'], ['D13.444.308.480', ... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of diltiazem on occupational Raynaud's syndrome (vibration disease). | An open trial on the therapeutic effect of diltiazem, a calcium antagonist, was conducted on occupational Raynaud's syndrome (vibration disease). Seventeen men with vibration disease were studied. The mean age was 54 years. No patient had cardiovascular disease. Primary and secondary cases of Raynaud's phenomenon were ... | ['Benzazepines', 'Cold Temperature', 'Diltiazem', 'Hand', 'Humans', 'Male', 'Middle Aged', 'Occupational Diseases', 'Raynaud Disease', 'Vibration'] | 4,083,566 | [['D03.633.100.079'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D03.633.100.079.150'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C24'], ['C14.907.617.812'], ['G01.374.930']... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Development of migrating tendon-bone attachments involves replacement of progenitor populations. | Tendon-bone attachment sites, called entheses, are essential for musculoskeletal function. They are formed embryonically by Sox9+ progenitors and continue to develop postnatally, utilizing Gli1 lineage cells. Despite their importance, we lack information on the transition from embryonic to mature enthesis and on the re... | ['Animals', 'Animals, Newborn', 'Bone and Bones', 'Cell Compartmentation', 'Cell Death', 'Cell Lineage', 'Embryo, Mammalian', 'Embryonic Development', 'Female', 'Hedgehog Proteins', 'Male', 'Mice, Inbred C57BL', 'Models, Biological', 'Movement', 'Osteoclasts', 'Phagocytes', 'SOX9 Transcription Factor', 'Stem Cells', 'T... | 30,504,126 | [['B01.050'], ['B01.050.050.282'], ['A02.835.232', 'A10.165.265'], ['G04.128'], ['G04.146'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['A16.254'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['D12.644.276.671', 'D12.776.467.671', 'D23.529.671'], ['B01.050.050.199.520.520.420... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Teleconsultation via the web: an analysis of the type of questions that Iranian patients ask. | We evaluated an ask-the-doctor service which was set up as one of the accessory services of a health education website in Iran. The study lasted for five months. A total of 500 enquiries were submitted to the question and answer system. Eighty enquiries were excluded because they were duplicated submissions, not replie... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Family', 'Female', 'Humans', 'Iran', 'Male', 'Middle Aged', 'Physician-Patient Relations', 'Remote Consultation', 'Young Adult'] | 21,844,170 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.350'], ['M01.060.116.630'], ['F01.829.401.650.675', 'N05.300.660.625'], ['L01.178.847.652.550', 'N04.452.758.849.550', 'N... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
N-nitro-L-arginine and indomethacin do not affect endothelin-induced constriction of large and small coronary arteries in the anaesthetized greyhound. | 1. The aim of this study was to investigate whether endothelin-1 (ET-1)-induced constriction of large and small coronary arteries in the anaesthetized greyhound is modulated by the endogenous release of nitric oxide or prostanoids. 2. ET-1 (1-100 ng/kg) and the alpha1-adrenoceptor agonist phenylephrine (0.5-2 mu g/kg),... | ['Animals', 'Arginine', 'Coronary Vessels', 'Dogs', 'Dose-Response Relationship, Drug', 'Endothelin-1', 'Female', 'Indomethacin', 'Male', 'Phenylephrine'] | 8,713,496 | [['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['A07.015.114.269', 'A07.015.908.194'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.644.276.400.225', 'D12.776.467.400.225', 'D23.529.400.225'], ['D03.633.100.473.420'], ['D02.033.100.291.617', 'D02.0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils. | The aggregation of alpha-synuclein has been implicated as a critical step in the development of Parkinson's disease. Parkinson's disease is a progressive neurodegenerative disorder caused by the loss of dopaminergic neurons from the substantia nigra; currently, no cure exists. Baicalein is a flavonoid with antioxidant ... | ['Anaerobiosis', 'Benzothiazoles', 'Circular Dichroism', 'Escherichia coli', 'Flavanones', 'Flavonoids', 'Humans', 'Light', 'Lysine', 'Microscopy, Atomic Force', 'Molecular Weight', 'Nerve Tissue Proteins', 'Oxidation-Reduction', 'Protein Conformation', 'Quinones', 'Scattering, Radiation', 'Solubility', 'Spectrometry, ... | 15,096,521 | [['G02.111.062', 'G03.078'], ['D03.383.129.708.089', 'D03.633.100.185'], ['E05.196.867.151'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D03.383.663.283.266.450.252', 'D03.633.100.150.266.450.252'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and characterization of a novel reagent containing dansyl group, which specifically alkylates sulfhydryl group: an example of application for protein chemistry. | We have synthesized a novel reagent containing dansyl group, iodoacethyl dansylcadaverine (IADC), which specifically alkylates sulfhydryl groups. The carboxyl group of iodoacetic acid was activated with dicyclohexylcarbodiimide and was condensed with amino group of dansylcadaverine. Purity and chemical structure of IAD... | ['Amino Acid Sequence', 'Animals', 'Blotting, Western', 'Cadaverine', 'Chickens', 'Cysteine', 'Dansyl Compounds', 'Dithionitrobenzoic Acid', 'Glutathione', 'Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)', 'Molecular Sequence Data', 'Muscles', 'Peptide Fragments', 'Proteins', 'Sensitivity and Specificity', ... | 15,892,976 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D02.092.211.415.261', 'D02.092.782.258.174'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Quantitative real-time 3-dimensional stress echocardiography: a preliminary investigation of feasibility and effectiveness. | BACKGROUND: Use of rapidly emerging real-time 3-dimensional (3D) echocardiography promises to improve the diagnostic accuracy of stress echocardiography (SE). However, widespread acceptance of 3D-SE, based on real-time 3D echocardiography, is hampered in part by lack of efficient, accurate, and objective analysis tools... | ['Adult', 'Aged', 'Cohort Studies', 'Coronary Artery Disease', 'Echocardiography, Stress', 'Echocardiography, Three-Dimensional', 'Endocardium', 'Feasibility Studies', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Male', 'Middle Aged', 'Myocardial Contraction', 'Myocardial Ischemia', 'Observer Variation',... | 17,218,197 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E01.370.350.130.750.228', 'E01.370.350.850.220.228', 'E01.370.370.380.220.228'], ['E01.370.350.130.750.230', 'E01.370.350.400.200... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Expression of coproporphyrinogen oxidase and synthesis of hemoglobin in human erythroleukemia K562 cells. | Coproporphyrinogen oxidase (CPOX), the sixth enzyme in the heme-biosynthetic pathway, catalyzes oxidative decarboxylation of coproporphyrinogen to protoporphyrinogen and is located in the intermembrane space of mitochondria. To clarify the importance of CPOX in the regulation of heme biosynthesis in erythroid cells, we... | ['Aminolevulinic Acid', 'Animals', 'Base Sequence', 'Coproporphyrinogen Oxidase', 'DNA Primers', 'Gene Expression Regulation, Neoplastic', 'Hemoglobins', 'Humans', 'K562 Cells', 'Leukemia, Erythroblastic, Acute', 'Mice', 'Oligonucleotides, Antisense', 'Transfection', 'Transforming Growth Factor beta'] | 11,248,690 | [['D02.241.755.547.276', 'D12.125.262'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.682.660.250'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.308.370'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.21... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Multicenter phase 2 trial of sirolimus for tuberous sclerosis: kidney angiomyolipomas and other tumors regress and VEGF- D levels decrease. | BACKGROUND: Tuberous sclerosis (TSC) related tumors are characterized by constitutively activated mTOR signaling due to mutations in TSC1 or TSC2.METHODS: We completed a phase 2 multicenter trial to evaluate the efficacy and tolerability of the mTOR inhibitor, sirolimus, for the treatment of kidney angiomyolipomas.RESU... | ['Adolescent', 'Adult', 'Aged', 'Angiomyolipoma', 'Anti-Bacterial Agents', 'Female', 'Humans', 'Kidney Neoplasms', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Sirolimus', 'Tuberous Sclerosis', 'Vascular Endothelial Growth Factor D', 'Young Adult'] | 21,915,260 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C04.557.450.550.125', 'C04.557.450.692.249'], ['D27.505.954.122.085'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['C04.588.274.623', 'C06.301.623'... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The invention of artificial fertilization in the eighteenth and nineteenth century. | Artificial insemination and other fertilization techniques are today considered central to the history of reproductive medicine. The medical treatment of infertile couples, however, constitutes just a small part of the whole story of artificial fertilization. Lazzaro Spallanzani (1729-1799) in particular, said to have ... | ['Animal Husbandry', 'Animals', 'History, 18th Century', 'Insemination, Artificial', 'Inventions', 'Natural History'] | 28,523,637 | [['J01.040.090'], ['B01.050'], ['K01.400.504.875'], ['E02.875.800.937', 'E05.820.800.937', 'G08.686.784.363.492'], ['J01.897.400'], ['H01.158.273.602', 'H01.770.552', 'K01.400.703']] | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Complications of surgery for arteriovenous malformations of the brain. | A series of 112 patients undergoing complete surgical resection of arteriovenous malformations (AVM's) of the brain between 1974 and 1990 were analyzed for complications and 12-month outcomes. The cohort consisted of 44 patients with small AVM's (< 2 cm in diameter), 43 patients with medium-sized AVM's (2 to 4 cm in di... | ['Adolescent', 'Adult', 'Aged', 'Australia', 'Cerebral Hemorrhage', 'Child', 'Child, Preschool', 'Cohort Studies', 'Female', 'Humans', 'Infant', 'Intracranial Arteriovenous Malformations', 'Male', 'Middle Aged', 'Odds Ratio', 'Postoperative Complications', 'Regression Analysis', 'Sex Factors', 'Survival Rate'] | 8,421,199 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['Z01.639.100', 'Z01.678.100.373'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.11... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Sustained accumulation of antigen-presenting cells after infection promotes local T-cell immunity. | Antigen-presenting cells (APC), such as dendritic cells (DC) and macrophages, are critical for T-cell-mediated immunity. Although it is established that memory T cells accumulate and persist in peripheral tissues after the resolution of infection, whether this is also the case for APC remains unclear. Here, we report t... | ['Animals', 'Antigen Presentation', 'CD4-Positive T-Lymphocytes', 'Cell Movement', 'Dendritic Cells', 'Herpes Simplex', 'Humans', 'Interferon-gamma', 'Lymphocyte Activation', 'Macrophages', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Receptors, CCR2', 'Simplexvirus'] | 28,722,019 | [['B01.050'], ['G12.119', 'G12.450.050.400.070'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['G04.198', 'G07.568.500.180'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['C01.925.256.466.382', 'C01.925.825.320', 'C17.800.838.790.320'], ['... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The diagnostic accuracy of cervical biopsies in determining cervical lesions: an audit. | OBJECTIVE: The present audit was carried out to assess the diagnostic accuracy of cervical punch biopsy during colposcopy in comparison with diagnosis from subsequent cone excision.DESIGN AND SETTING: Retrospective analysis was performed by examining the histopathology reports for paired cervical punch biopsies and cer... | ['Adult', 'Aged', 'Biopsy', 'Cervical Intraepithelial Neoplasia', 'Female', 'Humans', 'Middle Aged', 'Retrospective Studies', 'Sensitivity and Specificity', 'Uterine Cervical Neoplasms', 'Young Adult'] | 22,558,890 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.557.470.200.240.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Is Whole-Exome Sequencing an Ethically Disruptive Technology? Perspectives of Pediatric Oncologists and Parents of Pediatric Patients With Solid Tumors. | BACKGROUND: It has been anticipated that physician and parents will be ill prepared or unprepared for the clinical introduction of genome sequencing, making it ethically disruptive.PROCEDURE: As a part of the Baylor Advancing Sequencing in Childhood Cancer Care study, we conducted semistructured interviews with 16 pedi... | ['Child', 'Ethics, Medical', 'Exome', 'Humans', 'Interview, Psychological', 'Medical Oncology', 'Molecular Sequence Data', 'Neoplasms', 'Patients', 'Physicians'] | 26,505,993 | [['M01.060.406'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['G05.360.340.011'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.669.599'], ['H02.403.429.515'], ['L01.453.245.667'], ['C04'], ['M01.643'], ['M01.526.485.810', 'N02.360.810']] | ['Named Groups [M]', 'Humanities [K]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Aches, pains and headache: an unusual combination of hypothyroidism, vitamin D deficiency, cervical radiculopathy and cortical vein sinus thrombosis. | A young obese woman was admitted with vague aches and pains, including a headache. At first a provisional diagnosis of depression/myofacial pain syndrome was considered. Later, on evaluation, she was diagnosed to have hypothyroidism and vitamin D deficiency. One week into treatment, her neck pain and headache got worse... | ['Female', 'Headache', 'Humans', 'Hypothyroidism', 'Magnetic Resonance Imaging', 'Pain', 'Papilledema', 'Radiculopathy', 'Retinal Hemorrhage', 'Sinus Thrombosis, Intracranial', 'Vitamin D Deficiency', 'Young Adult'] | 26,156,835 | [['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.482'], ['E01.370.350.825.500'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['C10.292.700.900', 'C11.640.710'], ['C10.668.829.820'], ['C11.290.807', 'C11.768.710', 'C23.550.414.756.775'], ['C10.228.140.300.525.425.500', ... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[A case of Exophiala dermatitidis ulceration]. | The authors present one case of corneal Exophiala dermatitidis ulceration. This case is analyzed in the field of corneal mycosis infection. Classification, rate, clinical history, biomicroscopy aspects will be discussed. Technical samples will be described. Anatomopathologic slides will be discussed. Finally the medica... | ['Adult', 'Antifungal Agents', 'Corneal Ulcer', 'Drug Therapy, Combination', 'Exophiala', 'Eye Infections, Fungal', 'Female', 'Humans'] | 9,810,090 | [['M01.060.116'], ['D27.505.954.122.136'], ['C01.375.177', 'C11.204.564.225', 'C11.294.177'], ['E02.319.310'], ['B01.300.107.366', 'B01.300.381.355'], ['C01.150.703.320', 'C01.375.450', 'C11.294.450'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The context of chest beating and hand clapping in wild western gorillas (Gorilla gorilla gorilla). | Loud auditory gestures that are produced by repetitively percussing body parts are rare in primate repertoires and have been mostly observed in captive settings. Gorillas produce two of the most conspicuous long-range signals of this type: chest beating and hand clapping. Here we present the first systematic analysis o... | ['Age Factors', 'Animal Communication', 'Animals', 'Congo', 'Female', 'Gestures', 'Gorilla gorilla', 'Hand', 'Male', 'Social Behavior'] | 31,894,436 | [['N05.715.350.075', 'N06.850.490.250'], ['F01.145.113.055'], ['B01.050'], ['Z01.058.290.100.140'], ['F01.145.209.530.538.445'], ['B01.050.150.900.649.313.988.400.112.400.375'], ['A01.378.800.667'], ['F01.145.813']] | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Novel hyaluronan-based nanocarriers for transmucosal delivery of macromolecules. | The goal of this work was to design a new nanocarrier composed of the glycosaminoglycan hyaluronan and the polysaccharide chitosan, intended for the transmucosal delivery of macromolecules. The nanoparticles were characterized for their size and superficial charge. The incorporation of hyaluronan was verified by agaros... | ['Chitosan', 'Cyclosporine', 'Drug Carriers', 'Drug Delivery Systems', 'Hyaluronic Acid', 'Macromolecular Substances', 'Materials Testing', 'Nanoparticles', 'Serum Albumin, Bovine'] | 18,236,434 | [['D05.750.078.139.500', 'D09.698.211.500'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['D26.255.260', 'E02.319.300.380'], ['E02.319.300'], ['D09.698.373.475'], ['D05'], ['E05.570'], ['J01.637.512.600'], ['D12.776.034.841.540', 'D12.776.124.727.875']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Necessity for reassessment of patients with serogroup 2 hepatitis C virus (HCV) and undetectable serum HCV RNA. | We encountered a patient positive for anti-hepatitis C virus (HCV) whose serum HCV RNA was undetectable with the Roche AmpliPrep/Cobas TaqMan HCV assay (CAP/CTM) version 1 but showed a high viral load with the Abbott RealTime HCV assay (ART). Discrepancies in the detectability of serum HCV RNA were investigated among 8... | ['Hepacivirus', 'Hepatitis C', 'Hepatitis C Antibodies', 'Humans', 'Male', 'Middle Aged', 'Mutation', 'RNA, Viral', 'Serum', 'Viral Load'] | 24,478,486 | [['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['D12.776.124.486.485.114.254.450.510', 'D12.776.124.790.651.114.254.450.510', 'D12.776.377.715.548.114.254.450.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G0... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Direct enzymatic production of oligosaccharide mixtures from sugar beet pulp: experimental evaluation and mathematical modeling. | The potential of sugar beet pulp as raw material for neutral and acidic oligosaccharide production by direct enzymatic treatment was evaluated. The effect of the polygalacturonase to solid ratio (PGaseSR), cellulase activity to polygalacturonase activity ratio (CPGaseR), and reaction time (t) on several dependent varia... | ['Aspergillus', 'Beta vulgaris', 'Cellulase', 'Fungal Proteins', 'Hydrolysis', 'Models, Theoretical', 'Oligosaccharides', 'Polygalacturonase', 'Polysaccharides', 'Trichoderma'] | 19,530,718 | [['B01.300.381.081'], ['B01.650.940.800.575.912.250.200.399'], ['D08.811.277.450.420.200.200'], ['D12.776.354'], ['G02.380'], ['E05.599'], ['D09.698.629'], ['D08.811.277.450.800'], ['D09.698'], ['B01.300.381.910']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Targeted oligonucleotide delivery in human lymphoma cell lines using a polyethyleneimine based immunopolyplex. | The efficacy of antisense gene therapy depends on efficient delivery of oligonucleotides into targeted cells. Although polyethyleneimine based polyplexes have been reported as good transfection reagents, they are inefficient in lymphoid cell transfection. We report the construction of an immunopolyplex, a targeted nonv... | ['Drug Delivery Systems', 'Genetic Vectors', 'Humans', 'Lymphoma', 'Oligonucleotides', 'Polyethyleneimine', 'Tumor Cells, Cultured'] | 12,220,845 | [['E02.319.300'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386', 'C15.604.515.569', 'C20.683.515.761'], ['D13.695.578.424'], ['D02.455.326.271.665.550.600', 'D02.491.650', 'D05.750.716.507.600', 'D25.720.716.507.600', 'J01.637.051.720.716.507.600'], ['A11.251.860']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Classification of brain disease from magnetic resonance images based on multi-level brain partitions. | In this paper, we present a classification method based on the multi-level brain partitions. Bag-of-visual-words model is used. Firstly, the representative SIFT features are extracted from brain template as the basic visual words. Secondly, individual MR images are described using the basic visual words and support vec... | ['Alzheimer Disease', 'Brain', 'Humans', 'Magnetic Resonance Imaging', 'Parkinson Disease', 'Support Vector Machine'] | 28,269,603 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'], ['G17.035.250.500.500.500', 'L01.224.050.375.530.500.500']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Methodologic aspects of isolated ultrafiltration of the blood in nonspecialized units]. | 14 isolated ultrafiltration procedures have been performed in 7 patients, using AT-196 device and renal dialyzer DIP-02-02. Volumetric blood flow was 100-120 ml/min; 1.0-1.2 l of ultrafiltrate were removed during 1 h. The patients' conditions gradually improved in the course of ultrafiltration procedure. A simple metho... | ['Acute Kidney Injury', 'Hemofiltration', 'Humans'] | 2,596,725 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['E02.870.225', 'E04.292.471'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The placebo effect. Is it important in diverticular disease? | Thirty patients with diverticular disease confirmed by barium enema examination were entered into a three-month double-blind trial of two tablets of methylcellulose (Celevac) daily or two placebo tablets daily. As these tablets were indistinguishable it was possible to cross over nine of the patients and follow them fo... | ['Aged', 'Clinical Trials as Topic', 'Diverticulum, Colon', 'Drug Evaluation', 'Female', 'Humans', 'Male', 'Methylcellulose', 'Middle Aged', 'Placebos', 'Tablets'] | 324,270 | [['M01.060.116.100'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['C06.405.205.282.750.500', 'C23.300.415.500'], ['E05.290.625', 'E05.337.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.365.180.663'], ['M01.060.116.630'], ['D26.660', 'E02.785'], ['D26.255.830']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gold-catalyzed oxide nanopatterns for the directed assembly of Ge island arrays on Si. | The heteroepitaxial growth of Ge on Au-patterned Si(001) is investigated using in situ spectromicroscopy. Patterning of a hydrogen-terminated Si surface with a square array of Au dots followed by brief exposure to air leads to the spontaneous, local oxidation of Si. The resulting oxide nanopattern limits the surface mi... | ['Crystallization', 'Germanium', 'Gold', 'Macromolecular Substances', 'Materials Testing', 'Molecular Conformation', 'Nanostructures', 'Nanotechnology', 'Oxides', 'Particle Size', 'Silicon', 'Surface Properties'] | 17,672,506 | [['E05.196.300', 'G02.171'], ['D01.268.513.750', 'D01.268.556.305', 'D01.552.544.305'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['D05'], ['E05.570'], ['G02.111.570.820'], ['J01.637.512'], ['H01.603', 'J01.897.520.600'], ['D01.248.497.158.685', 'D01.650.550'], ['G02.712'], ['D01.268.513.937'], ['G02.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Use of S-[2,3-bispalmitoyiloxy-(2R)-propyl]-R-cysteinyl-amido-monomethoxy polyethylene glycol as an adjuvant improved protective immunity associated with a DNA vaccine encoding Cu,Zn superoxide dismutase of Brucella abortus in mice. | This study was conducted to evaluate the immunogenicity and protective efficacy of a DNA vaccine encoding Brucella abortus Cu,Zn superoxide dismutase (SOD) using the Toll-like receptor 2/6 agonist S-[2,3-bispalmitoyiloxy-(2R)-propyl]-R-cysteinyl-amido-monomethoxy polyethylene glycol (BPPcysMPEG) as an adjuvant. Intrana... | ['Adjuvants, Immunologic', 'Administration, Intranasal', 'Animals', 'Antibodies, Bacterial', 'Bacterial Proteins', 'Bronchoalveolar Lavage Fluid', 'Brucella Vaccine', 'Brucella abortus', 'Brucellosis', 'Cell Proliferation', 'Cytotoxicity Tests, Immunologic', 'Disease Models, Animal', 'Female', 'Immunoglobulin A, Secret... | 25,165,025 | [['D27.505.696.477.067'], ['E02.319.267.120.655.500'], ['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D12.776.097'], ['E05.927.100.500'], ['D20.215.894.135.134'], ['B03.440.400.425.215.500.100', 'B03.660.050.070.100.100'], ['C01.150.252.400.167'], ['G04.161... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
First results of the RAMBAS experiment on investigation of the radiation mechanism of chiral influence. | The first results of the RAdiation Mechanism of Biomolecular ASymmetry (RAMBAS) experiment on investigation of the radiation mechanism of the influence on chiral molecules, as a factor leading to origination of chiral asymmetry are presented. It was found that irradiation of simple achiral materials by a flux of electr... | ['Amino Acids', 'Circular Dichroism', 'Origin of Life', 'Protons', 'Radiation, Ionizing', 'Stereoisomerism'] | 18,302,005 | [['D12.125'], ['E05.196.867.151'], ['G16.650', 'I01.076.368.584.542'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['G01.750.750'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Enhanced biodegradation of diesel fuel through the addition of particulate organic carbon and inorganic nutrients in coastal marine waters. | Diesel fuel pollution in coastal waters, resulting from recreational boating and commercial shipping operations, is common and can adversely affect marine biota. The purpose of this study was to examine the effect of additions of particulate organic carbon (POC) in the form of naturally-occurring marsh grass (Spartina ... | ['Biodegradation, Environmental', 'Gasoline', 'Hydrocarbons', 'Marine Biology', 'Oceans and Seas', 'Poaceae', 'Seasons', 'Water Pollutants, Chemical'] | 8,782,394 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['D20.345.630.540', 'N06.230.132.258.630.540'], ['D02.455'], ['H01.158.273.248.750.500', 'H01.277.249.750.500', 'H01.277.750.500'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.756'], ['B01.650.940.800.575.912.250.822'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Molecular cloning and characterization of two genes encoding 2-Cys peroxiredoxins from Fasciola gigantica. | In Fasciola species, peroxiredoxin (Prx) serves as the major antioxidant enzyme to remove hydrogen peroxide that is generated from various metabolic reactions, because the parasites lack catalase, and only express glutathione peroxidases at minimal levels. We have cloned and characterized two genes, FgPrx-1 and FgPrx-2... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Blotting, Northern', 'Cattle', 'Cloning, Molecular', 'DNA, Complementary', 'Fasciola', 'Gene Expression Regulation, Enzymologic', 'Gene Library', 'In Situ Hybridization', 'Lymnaea', 'Mice', 'Mice, Inbred ICR', 'Molecular Sequence Data', 'Molecular Weight', 'Peroxired... | 20,093,115 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['B01.050.150.900.649.313.500.380.271'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['B01.050.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Nitropyrenes: isolation, identificaton, and reduction of mutagenic impurities in carbon black and toners. | Extracts of selected xerographic toners and copies were found to be mutagenic in the Salmonella assay. The activity was independent of the xerographic hardware and process and was traced to nitropyrenes present as impurities in the carbon black, the toner colorant. Manufacturing process changes resulted in a substantia... | ['Biotransformation', 'Carbon', 'Chromatography, High Pressure Liquid', 'Copying Processes', 'Drug Evaluation, Preclinical', 'Microsomes, Liver', 'Mutagens', 'Oxidation-Reduction', 'Pyrenes', 'Salmonella typhimurium'] | 6,996,095 | [['G03.171', 'G03.787.225', 'G07.690.725.225'], ['D01.268.150'], ['E05.196.181.400.300'], ['L01.280'], ['E05.290.750', 'E05.337.550'], ['A11.284.835.540.541'], ['D27.888.569.468'], ['G02.700', 'G03.295.531'], ['D02.455.426.559.847.799', 'D04.615.799'], ['B03.440.450.425.800.200.825', 'B03.660.250.150.710.160.760']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Should health-care providers in the United States have access to influenza vaccines formulated for the southern hemisphere? | BACKGROUND: Influenza is the most common vaccine-preventable disease in travelers. It circulates year-round in the tropics, November to March in the northern hemisphere (NH), and April to October in the southern hemisphere (SH). In 2005, approximately 8.5 million US adults aged 18 years and older traveled to the Caribb... | ['Asia', 'Attitude of Health Personnel', 'Data Collection', 'Humans', 'Influenza Vaccines', 'Influenza, Human', 'Latin America', 'Oceania', 'Orthomyxoviridae', 'Travel', 'West Indies'] | 19,090,800 | [['Z01.252'], ['F01.100.050', 'N05.300.100'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.215.894.899.302'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['Z01.107.424'], ['Z01.678'], ['B04.820.480.968'], ['I03.883'], ['Z01.107.0... | ['Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Blood pressure response to a community-based program and long-term cardiovascular outcome. | BACKGROUND: The significance in terms of the cardiovascular outcome of different patterns of blood pressure (BP) response to community-based activities has not been previously studied. The aim of our study was to evaluate the relationship between changes of BP observed during a community-based program and long-term rat... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Argentina', 'Blood Pressure', 'Cardiovascular Diseases', 'Cohort Studies', 'Community Health Services', 'Endpoint Determination', 'Female', 'Humans', 'Male', 'Middle Aged', 'Risk Factors', 'Socioeconomic Factors', 'Young Adult'] | 24,390,293 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['Z01.107.757.077'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N02.421.143'], ['E05.315'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Calcium carbonate antacids alter esophageal motility in heartburn sufferers. | Chewed calcium carbonate (CaCO3) rapidly neutralizes esophageal acid and may prevent reflux, suggesting another mechanism of action independent of acid neutralization. Calcium is essential for muscle tone. Our aim was to determine if luminal calcium released from chewed antacids improved esophageal motor function in he... | ['Adult', 'Antacids', 'Calcium Carbonate', 'Esophagus', 'Female', 'Heartburn', 'Humans', 'Hydrogen-Ion Concentration', 'Male', 'Middle Aged', 'Peristalsis', 'Prospective Studies', 'Tablets'] | 15,628,717 | [['M01.060.116'], ['D27.505.519.170', 'D27.505.954.483.080'], ['D01.146.275', 'D01.200.275.150.150', 'D01.578.200'], ['A03.556.875.500'], ['C23.888.821.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['M01.060.116.630'], ['G10.261.360.596'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Developmental origin and identity of song system neurons born during vocal learning in songbirds. | New neurons are added to the forebrain song control regions high vocal center (HVC) and Area X of juvenile songbirds but the identity and site of origin of these cells have not been fully characterized. We used oncoretroviral vectors to genetically label neuronal progenitors in different regions of the zebra finch late... | ['Animals', 'Animals, Newborn', 'Brain Mapping', 'Cholera Toxin', 'Dopamine and cAMP-Regulated Phosphoprotein 32', 'Finches', 'Genetic Vectors', 'Green Fluorescent Proteins', 'High Vocal Center', 'Homeodomain Proteins', 'Learning', 'Neurons', 'T-Box Domain Proteins', 'Vocalization, Animal', 'gamma-Aminobutyric Acid'] | 17,348,018 | [['B01.050'], ['B01.050.050.282'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['D08.811.913.400.725.115.180', 'D23.946.123.194', 'D23.946.330.150'], ['D12.776.631.249', 'D12.776.744.459'], ['B01.050.150.900.248.620.750.250'], ['G05.360.337'], ['D12.776.532.265'], ['A08.186.211.200.885.28... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tag-free microfluidic separation of cells against multiple markers. | Conventional cell separation against multiple markers generally requires the attachment of antibody tags, typically fluorescent or magnetic, to selected cell types in a heterogeneous suspension. This work describes how such separation can be accomplished in a series of microfluidic systems without the need for such tag... | ['Alginates', 'Antigens, CD34', 'Biomarkers', 'Cell Separation', 'Flow Cytometry', 'Glucuronic Acid', 'Hematopoietic Stem Cells', 'Hexuronic Acids', 'Humans', 'Hydrogel, Polyethylene Glycol Dimethacrylate', 'Microfluidic Analytical Techniques', 'Vascular Endothelial Growth Factor Receptor-2'] | 22,519,841 | [['D09.698.068'], ['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['D23.101'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['D02.2... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
In vivo evaluation of 5-[(18)F]fluoro-2'-deoxyuridine as tracer for positron emission tomography in a murine pancreatic cancer model. | We used a murine tumor progression model for the evaluation of potential proliferation markers using positron emission tomography (PET). 5-[(18)F]-2'-deoxyuridine ([(18)F]FdUrd) was synthesized with >98% radiochemical purity and investigated in a pancreatic cancer model, transforming growth factor alpha transgenic mice... | ['Animals', 'Cell Division', 'Disease Models, Animal', 'Disease Progression', 'Floxuridine', 'Fluorodeoxyglucose F18', 'Genes, p53', 'Mice', 'Mice, Transgenic', 'Pancreatic Neoplasms', 'RNA, Messenger', 'Radionuclide Imaging', 'Radiopharmaceuticals', 'Thymidine Kinase', 'Thymidylate Synthase', 'Transforming Growth Fact... | 11,358,795 | [['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.291.656'], ['D03.383.742.680.852.300.350', 'D13.570.230.430.432', 'D13.570.685.852.300.350'], ['D09.254.229.500'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Broadband enhancement of single photon emission and polarization dependent coupling in silicon nitride waveguides. | Single-photon (SP) sources are important for a number of optical quantum information processing applications. We study the possibility to integrate triggered solid-state SP emitters directly on a photonic chip. A major challenge consists in efficiently extracting their emission into a single guided mode. Using 3D finit... | ['Computer Simulation', 'Optics and Photonics', 'Photons', 'Silicon Compounds'] | 26,072,744 | [['L01.224.160'], ['H01.671.617', 'J01.293.688'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782'], ['D01.837']] | ['Information Science [L]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Ultrasound monitoring of ovarian follicular growth during spontaneous cycles in Nigerian women. | Thirty-nine spontaneous cycles in 34 women (22 patients from the infertility clinic and 12 normal volunteers) were serially studied by ultrasound to monitor follicular growth for ovulation prediction and detection. Ovulation was also confirmed by a mid-luteal phase progesterone assay using WHO match RIA kits. Ovulation... | ['Adolescent', 'Adult', 'Anthropometry', 'Cohort Studies', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Infertility, Female', 'Luteal Phase', 'Nigeria', 'Ovarian Follicle', 'Ovulation Detection', 'Progesterone', 'Reproducibility of Results', 'Ultrasonography'] | 1,308,083 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['G08.686.605.410'], ['Z01.058.290.190.565'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Recognition memory for emotional facial expressions in patients with focal cerebral lesions. | A test of memory for emotional facial expressions was administered to 49 brain-damaged and 15 control subjects. On this task, patients with right-hemisphere lesions were more impaired than left-hemisphere patients; also, patients with frontal lobe lesions were more impaired than patients with posterior brain damage. Wh... | ['Arousal', 'Attention', 'Brain Damage, Chronic', 'Discrimination Learning', 'Dominance, Cerebral', 'Emotions', 'Facial Expression', 'Female', 'Humans', 'Male', 'Memory', 'Mental Recall', 'Middle Aged', 'Visual Perception'] | 2,789,812 | [['F02.830.104', 'G11.561.035'], ['F02.830.104.214'], ['C10.228.140.140'], ['F02.463.425.280'], ['F02.830.297', 'G11.561.225'], ['F01.470'], ['E01.370.600.225', 'F01.145.209.530.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['F02.463.425.540.641'], ['M01.060.116.630'], ['F02.463.593.932']... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Between visit variability of thermal imaging of feet in people attending podiatric clinics with diabetic neuropathy at high risk of developing foot ulcers. | OBJECTIVE: People with diabetic neuropathy who have previously ulcerated are at high risk of re-ulceration. They should regularly attend podiatry clinics for surveillance and routine protective podiatric treatment. It has been suggested that inflammation prior to skin breakdown shows up as a hotspot on a thermal image ... | ['Aged', 'Ambulatory Care', 'Diabetic Foot', 'Diabetic Neuropathies', 'Female', 'Foot', 'Humans', 'Male', 'Middle Aged', 'Podiatry', 'Thermography'] | 31,362,275 | [['M01.060.116.100'], ['E02.760.106', 'N02.421.585.106'], ['C14.907.320.191', 'C17.800.893.592.450.200', 'C19.246.099.500.191', 'C19.246.099.937.250'], ['C10.668.829.300', 'C19.246.099.937'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H02.696'], ['E01.370.350.800', 'E05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Stable gastric pentadecapeptide BPC 157 heals rectovaginal fistula in rats. | AIM: Rectovaginal fistula is a devastating condition providing more than 99% of patients for surgical treatment. We hypothesized that rectovaginal fistula may be healed by therapy with stable gastric pentadecapeptide BPC 157, in consistence with its initial clinical application and effect on external fistulas.MAIN METH... | ['Animals', 'Anti-Ulcer Agents', 'Female', 'Peptide Fragments', 'Proteins', 'Rats', 'Rats, Wistar', 'Rectovaginal Fistula', 'Wound Healing'] | 26,872,976 | [['B01.050'], ['D27.505.954.483.203'], ['D12.644.541'], ['D12.776'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['C06.267.550.600.650', 'C06.405.469.471.600.650', 'C06.405.469.860.752.650', 'C13.351.500.894.767.249', 'C23.300.575.185.550.600.650', 'C23.300.575.925.558'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hair transplantation. | Hair transplantation is a technique in which hair follicles are harvested from the occipital area and re-transplanted in the frontal bald area. Hair transplantation is the most common cosmetic procedure in the United States nowadays despite the fact that it is expensive. Usually, patients need more than one session to ... | ['Adult', 'Alopecia', 'Costs and Cost Analysis', 'Cross-Cultural Comparison', 'Hair', 'Hair Follicle', 'Humans', 'Male', 'Saudi Arabia', 'Surgery, Plastic', 'Surgical Instruments', 'United States'] | 11,376,357 | [['M01.060.116'], ['C17.800.329.937.122', 'C23.300.035'], ['N03.219.151'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['A17.360'], ['A10.272.497.500', 'A17.360.710', 'A17.815.250.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.750'], ['H02.403.810.788'], ['E07.858.700'], ['Z01.107.567.875... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Possible involvement of the Ah receptor in the induction of cytochrome P-450IA1 under conditions of hydrodynamic shear in microcarrier-attached hepatoma cell lines. | The exposure of two hepatoma cell lines, Hep G2 and Hepa-1, to moderate hydrodynamic shear, in microcarrier-attached suspension cultures, resulted in the transient induction of cytochrome P450IA1 (CYP1A1). Both cell lines have been characterized with respect to their Ah receptor (AhR) concentrations and induce CYP1A1 i... | ['Alkaloids', 'Benzoflavones', 'Carcinoma, Hepatocellular', 'Cell Line', 'Culture Techniques', 'Cytochrome P-450 Enzyme System', 'Enzyme Induction', 'Humans', 'Kinetics', 'Liver Neoplasms', 'Microspheres', 'Polychlorinated Dibenzodioxins', 'Protein Kinase C', 'Receptors, Aryl Hydrocarbon', 'Staurosporine', 'Stress, Mec... | 7,887,922 | [['D03.132'], ['D03.383.663.283.266.450.175', 'D03.633.100.150.266.450.175'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A11.251.210'], ['E05.481.500'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['G05.308.320.200'], ['B01.050.150.900.649.313.988.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Defining moments in leadership character development. | Critical moments in life define one's character and clarify true values. Reflective leadership is espoused as an important practice for transformational leaders. Professional development educators can help surface and explore defining moments, strengthen leadership behavior with defining moments as a catalyst for chang... | ['Character', 'Education, Nursing, Continuing', 'Humans', 'Leadership', 'Nursing Staff', 'Staff Development', 'Teaching'] | 26,057,159 | [['F01.752.190'], ['I02.358.212.450', 'I02.358.462.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['M01.526.485.680', 'N02.360.680'], ['I02.574.700', 'N04.452.677.822'], ['I02.903']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
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