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e85037de90f9d9227fd3c680bd0ce306 | Rats were subchronically primed with nicotine , clozapine or saline . | [
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] | Nicotine and clozapine cross-prime the locus coeruleus noradrenergic system to induce long-lasting potentiation in the rat hippocampus. A priming-challenge schedule of nicotine treatment causes long-lasting potentiation (LLP), a form of synaptic plasticity closely associated with the norepinephrine (NE) neurotransmitte... | null | ### Instruction:
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Nicotine and clozapine cross-prime the locus coeruleus noradrenergic system to... |
09d51495e2d83ea5f32d530926d8541c | The chimeric anti- EGFR monoclonal antibody cetuximab has been approved for EGFR-expressing colorectal tumors in patients who progress after irinotecan-based chemotherapy in combination with irinotecan and in squamous cell head and neck carcinomas for patients with locally advanced disease in combination with radiation... | [
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] | [] | The future of anti-EGFR therapy. We report here on the state of our knowledge of the target--namely, the epidermal growth factor (EGF) and its receptor--and the challenges related to the methods of determination of the epidermal growth factor receptor (EGFR) and associated molecular pathways. A critical review of the a... | null | ### Instruction:
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The future of anti-EGFR therapy. We report here on the state of our knowledge ... |
22c52fc95d8815028638dbd0c82cb2ea | New agents , such as taxane , irinotecan and oxaliplatin , combined with old agents , such as cisplatin and 5-FU , are currently under evaluation to further improve treatment outcomes . | [
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"is_context_needed": true... | Chemotherapy for advanced gastric cancer: slow but further progress. Gastric cancer remains a significant problem in terms of global health, and is the most common cancer in Korea. Surgery is the only potentially curative treatment for localized gastric cancer, but most cases present at an advanced stage. Randomized tr... | null | ### Instruction:
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Chemotherapy for advanced gastric cancer: slow but further progress. Gastric c... |
1007329826934be65ae5d787ac699734 | Taxinol , Gemcitabine ( GEM ) , Navelbine ( NVB ) , Edatrexate ( ETX ) , CPT-11 and high dose Epirubicin ( EPI HD ) are recommended as new effective drugs . | [
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] | [] | Non-surgical therapy for patients with advanced non-small cell lung cancer. Advanced non-small cell lung cancer (NSCLC) denotes those of TNM stage III and IV. NSCLC has its specific characteristics in respect of oncological behaviour, molecular biology, sensitivity to chemotherapy (CT) and radiotherapy (RT), and requir... | null | ### Instruction:
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Non-surgical therapy for patients with advanced non-small cell lung cancer. Ad... |
5462aa5679ca8723fbb384a42f1503a3 | One group was given enalapril ( EN ) 50 mg/l dissolved in the drinking water ; the second received lovastatin ( L ) 15 mg/kg given daily by gavage ; the third received both agents ; the fourth was left untreated , and the final group received no puromycin and served as the control group . | [
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] | The combination of lovastatin and enalapril in a model of progressive renal disease. puromycin-induced nephrotic syndrome is an animal model of progressive renal disease. Both angiotensin converting enzyme inhibitors and lipid-lowering agents have been used to preserve renal structure and function in this model, althou... | null | ### Instruction:
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The combination of lovastatin and enalapril in a model of progressive renal di... |
46c1af10ca741651727ab83341728298 | Using the Killing-curve method , we tested the in vitro bactericidal activity of fosfomycin alone or in combination with vancomycin or teicoplanin at a concentration of 8 microg/mL , that is easily achievable in serum at standard dosing regimens , against seven methicillin-resistant Staphylococcus aureus strains , isol... | [
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] | In vitro activity of fosfomycin in combination with vancomycin or teicoplanin against Staphylococcus aureus isolated from device-associated infections unresponsive to glycopeptide therapy. fosfomycin is a molecule that inhibits the early stage of peptidoglycan synthesis and shows a broad-spectrum bactericidal activity ... | null | ### Instruction:
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In vitro activity of fosfomycin in combination with vancomycin or teicoplanin ... |
f4bb3b5302fc3c34787fb3c978b1644e | Combination therapy with mitomycin , tamoxifen , and UFT proved to be an effective postoperative chemoendocrine therapy for stage II , ER-positive breast cancer . | [
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] | UFT and mitomycin plus tamoxifen for stage II, ER-positive breast cancer. Hokkaido ACETBC Study Group. A trial was designed to examine the combination of UFT and mitomycin (Mutamycin) plus tamoxifen (Nolvadex) as postoperative adjuvant therapy in the treatment of patients with stage II, estrogen receptor (ER)-positive ... | null | ### Instruction:
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UFT and mitomycin plus tamoxifen for stage II, ER-positive breast cancer. Hokk... |
70ee0c1e56cac0e3bb9d3c835721416e | The remaining 76 patients did not receive anti-thymocyte globulin but were given cyclosporine A and methotrexate or mycophenolate mofetil ( group 3 ) . | [
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] | The impact of graft-versus-host disease prophylaxis in reduced-intensity conditioning allogeneic stem cell transplant in acute myeloid leukemia: a study from the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation. The impact of the intensity of graft-versus-host-disease immunoprophy... | null | ### Instruction:
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The impact of graft-versus-host disease prophylaxis in reduced-intensity condi... |
b83939edbb4e56478efb8e3be32e53e1 | Propranolol significantly decreased the maximum plasma concentration ( Cmax ) and area under the plasma concentration-time curve ( AUC ) of lacidipine ( by 38 % and 42 % , respectively ) whereas lacidipine significantly increased the Cmax and AUC of propranolol ( by 35 % and 26 % , respectively ) ; neither the time to ... | [
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] | The pharmacokinetic and pharmacodynamic interaction between lacidipine and propranolol in healthy volunteers. The pharmacokinetic and pharmacodynamic profiles of lacidipine, a 1,4-dihydropyridine calcium antagonist, and the beta-adrenoceptor blocker propranolol were determined alone and in combination in 24 healthy mal... | null | ### Instruction:
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The pharmacokinetic and pharmacodynamic interaction between lacidipine and pro... |
f471cf9397ea607071e678ff48f72b27 | The patient received chemotherapy comprising vincristine , actinomycin D , doxorubicin , cisplatin , and cyclophosphamide . | [
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] | Autologous peripheral blood stem cell transplantation in a patient with relapsed pleuropulmonary blastoma. Pleuropulmonary blastoma (PPB) is a rare and aggressive primary intrathoracic neoplasma of children. The prognosis is extremely poor with frequent metastasis to the brain and bone. We present a 4-year-old girl wit... | null | ### Instruction:
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Autologous peripheral blood stem cell transplantation in a patient with relaps... |
c27cefd30656336acf4b74f488e05d74 | It was found that the increase in acoustic startle responses observed with ethanol or nicotine was attenuated by haloperidol . | [
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] | [] | Nicotine and ethanol enhancements of acoustic startle reflex are mediated in part by dopamine in C57BL/6J mice. nicotine has been shown to have additive as well as antagonistic effects on behavior stimulated by ethanol. Here, we examine the effects of nicotine, ethanol, and the coadministration of each drug on acoustic... | null | ### Instruction:
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Nicotine and ethanol enhancements of acoustic startle reflex are mediated in p... |
813dcb872eb1f84227a34f52386ba8d0 | The use of tacrolimus ( 88 % vs 77 % , P=.02 ) and cytolytic therapy ( 81 % vs 46 % , P < .0001 ) was likewise greater among patients who received ganciclovir prophylaxis . | [
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] | [] | Ganciclovir prophylaxis delays but does not prevent cytomegalovirus infection in renal transplant recipients. Cytomegalovirus (CMV) infection is associated with reduced graft and patient survival among renal transplant recipients. The purpose of this study was to examine the effect of routine prophylaxis with 12 weeks ... | null | ### Instruction:
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Ganciclovir prophylaxis delays but does not prevent cytomegalovirus infection ... |
c0ee5c12e6ffd1a92a439a953fce6247 | Because gemcitabine has been considered a standard treatment for advanced pancreatic cancer for the past decade , several randomized trials have tested the combination of gemcitabine plus a second agent , including platinum based agents , topoisomerase inhibitors , taxanes , bevacizumab and cetuximab , as biologically ... | [
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] | First-line treatment for advanced pancreatic cancer. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011. Pancreatic adenocarcinoma remains a treatment-refractory cancer. Although pancreatic adenocarcinoma is only the 10th most common cause of new cancer in th... | null | ### Instruction:
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First-line treatment for advanced pancreatic cancer. Highlights from the "2011... |
38329cd40dbe6ad6067d19e9582d38cb | Gemcitabine and recently FOLFIRINOX ( 5-flourouracil , leucovorin , oxaliplatin and irinotecan ) have provided some limited survival advantage in advanced pancreatic cancer . | [
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... | [] | Immunotherapy updates in pancreatic cancer: are we there yet? Pancreatic cancer is a lethal disease and remains one of the most resistant cancers to traditional therapies. Historically, chemotherapy or radiotherapy did not provide meaningful survival benefit in advanced pancreatic cancer. Gemcitabine and recently FOLFI... | null | ### Instruction:
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Immunotherapy updates in pancreatic cancer: are we there yet? Pancreatic cance... |
69e1dda67a8c14cb6423a43d0b603f56 | No synergism was found against Pneumococci and Meningococci but also no antagonism of the lower MIC and MBC values seen with ampicillin and penicillin G. The combination of chloramphenicol with either penicillin or ampicillin constitutes a clinically successful therapeutic regimen which is now also proven by in vitro i... | [
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] | [Bactericidal action of chloramphenicol and synergism with beta-lactam antibiotics]. Excellent clinical results were observed with the combination therapy of chloramphenicol with beta-lactam-antibiotics in the treatment of purulent meningitis. This came as a surprise as bacteriostatic antibiotics like chloramphenicol a... | null | ### Instruction:
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[Bactericidal action of chloramphenicol and synergism with beta-lactam antibio... |
161afbd8e6bbb825a43f76766b0d37a0 | Similarly , nifedipine , nitroglycerin and hydralazine should not to be considered first-line therapies in the management of hypertensive crises because these agents are associated with significant toxicities and/or adverse effects . | [
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] | [] | Treatment of acute severe hypertension: current and newer agents. Approximately 72 million people in the US experience hypertension. Worldwide, hypertension may affect as many as 1 billion people and be responsible for approximately 7.1 million deaths per year. It is estimated that approximately 1% of patients with hyp... | null | ### Instruction:
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Treatment of acute severe hypertension: current and newer agents. Approximatel... |
d1848c9d6ebf91e701d7f2875f077be8 | Bendamustine is effective both with rituximab and as a monotherapy in rituximab-refractory patients . | [
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Bendamustine in chronic lymphocytic leukemia and refractory lymphoma. bendamus... |
d95caf8d1b6b298d37ffecb80c7bbbed | Ten micromoles of gefitinib reversed topotecan , SN-38 , and mitoxantrone resistance , and increased the intracellular topotecan accumulation in the resistant cells but not in the parental cells . | [
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"end... | [] | Gefitinib ("Iressa", ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance. gefitinib ("Iressa", ZD1839) is an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor, and the single agent is clinicall... | https://pubmed.ncbi.nlm.nih.gov/15735043/ | ### Instruction:
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Gefitinib ("Iressa", ZD1839), an epidermal growth factor receptor tyrosine kin... |
9553267587970e290dcd162f832fc386 | The effects of multiple combination chemotherapy with vincristine , cyclophosphamide ( Endoxan ) , methotrexate , 5-fluorouracil , adriamycin and prednisolone ( VEMFAH ) for advanced breast cancer . | [
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] | The effects of multiple combination chemotherapy with vincristine , cyclophosphamide ( Endoxan ) , methotrexate , 5-fluorouracil , adriamycin and prednisolone ( VEMFAH ) for advanced breast cancer . Thirty-eight patients with advanced breast cancer were treated with the 'VEMFAH' multiple-drug combination chemotherapy, ... | https://pubmed.ncbi.nlm.nih.gov/3902267/ | ### Instruction:
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The effects of multiple combination chemotherapy with vincristine , cyclophosp... |
1e789327329484c793977a63b0ab0cfa | Association of rash with outcomes in a randomized phase II trial evaluating cetuximab in combination with mitoxantrone plus prednisone after docetaxel for metastatic castration-resistant prostate cancer . | [
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Association of rash with outcomes in a randomized phase II trial evaluating ce... |
0a4f78997b6f89533c19850c90d7954f | CDM mice show decreased Homer1a and Homer1b/c mRNA expression in cortex and blood samples , while chronic treatment with imipramine and fluoxetine or acute ketamine application increases their level only in the cortex . | [
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] | Antidepressant treatment is associated with epigenetic alterations of Homer1 promoter in a mouse model of chronic depression. Understanding the neurobiology of depression and the mechanism of action of therapeutic measures is currently a research priority. We have shown that the expression of the synaptic protein Homer... | https://pubmed.ncbi.nlm.nih.gov/33128940/ | ### Instruction:
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Antidepressant treatment is associated with epigenetic alterations of Homer1 p... |
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0bae4bf9eca270aebdabe9ab47f382f2 | In addition , stimulation of erythropoiesis with recombinant human erythropoietin , supplemental iron therapy , and improving haemostasis by aprotinin may further reduce homologous blood requirements . | [
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661e745b70596299921deeab58a3d21e | In the presence of heparin and cortisone and of cortisone alone there was a 4.5- and 2.3-fold reduction , respectively , in the growth of the 9L glioma . | [
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Growth inhibition of the 9L glioma using polymers to release heparin and corti... |
7dffebdf49843e64c3a7aa9b3812bcc1 | Dibutyryl cAMP , forskolin and theophylline stimulated secretion of pancreastatin and somatostatin . | [
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b8c0eb9ae6e7ea066e515e69ee2799b5 | It was the aim of this study to evaluate maintenance therapy with bevacizumab + capecitabine following induction with bevacizumab + capecitabine + oxaliplatin ( XELOX ) versus bevacizumab + XELOX until progression as first-line therapy in metastatic colorectal cancer ( mCRC ) . | [
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Bevacizumab + capecitabine as maintenance therapy after initial bevacizumab + ... |
6f09f4aa6c650b00d751ef90c70bf1df | We chose to assess the chemopreventive effect of three different drugs : pioglitazone , lanreotide and S-trans-trans-farnesylthiosalicylic acid ( FTS ) . | [
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"text": "S-trans-trans-farnesylthi... | [] | Chemoprevention of hepatocellular carcinoma. Proof of concept in animal models. In the present work, we have evaluated the possibility of preventing liver carcinogenesis in rats at two stages of development. In the first series of experiments, we induced foci of altered hepatocytes, (FAH) which represent the first even... | https://pubmed.ncbi.nlm.nih.gov/21563652/ | ### Instruction:
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70606f6869fb0cb024b34ef2853f9163 | Etoposide ( 25 mg , twice daily ) and prednisone ( 5 mg , twice daily ) were administered orally . | [
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1a4eea0fb32e8a01c262faf7fad66861 | Rosuvastatin + ezetimibe , simvastatin + ezetimibe , and atorvastatin + ezetimibe were the most cost-effective combination therapies for reducing LDL-C levels . | [
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The cost effectiveness of statin therapies in Spain in 2010, after the introdu... |
5385813964fa22e9fdbad267cad739de | This 40-week open-label extension of the 12-week double-blind Triple Therapy With Olmesartan Medoxomil , Amlodipine , and Hydrochlorothiazide in Hypertensive Patients Study ( TRINITY ) evaluated the efficacy and safety of triple-combination treatments with olmesartan medoxomil , amlodipine besylate , and hydrochlorothi... | [
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Long-term efficacy and safety of triple-combination therapy with olmesartan me... |
13d227c15f3afba751d934f49d59e018 | Nithiamide and chlortetracycline + sulfamethazine + penicillin were least effective in preventing SD during the infection + medication and postmedication periods . | [
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A swine dysentery model for evaluation of drug prophylaxis: efficacy of variou... |
5c88fa895583c022261c8290cb802c4e | The largest number of strains was resistant to gentamicin , followed by erythromycin . | [
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] | [] | Sensitivity of antibacterials of Staphylococcus aureus isolated from impetigo patients. We measured the sensitivity to antibacterials of Staphylococcus aureus isolated from impetigo lesions during one year (from July 1994 to July 1995). The largest number of strains was resistant to gentamicin , followed by erythromyci... | https://pubmed.ncbi.nlm.nih.gov/9283995/ | ### Instruction:
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Sensitivity of antibacterials of Staphylococcus aureus isolated from impetigo ... |
5b3c9e4fed209076e7d197b42242c429 | Behavioural impact of intraseptally released vasopressin and oxytocin in rats . | [
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Behavioural impact of intraseptally released vasopressin and oxytocin in rats ... |
923b1d414c3afb26d65e3beafbdfddf8 | Optimized 14 day sequential therapy was non-inferior to , but better tolerated than 10 day bismuth quadruple therapy and both may be used in first-line treatment in populations with low to intermediate clarithromycin resistance . | [
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14 day sequential therapy versus 10 day bismuth quadruple therapy containing h... |
5c6c7ff9d0b179779cae4a24b94343f9 | Initial treatment with either neoadjuvant chemoradiation ( CRT ) or induction FOLFOX ( 5-Fluorouracil , leucovorin , and oxaliplatin ) chemotherapy followed by CRT is considered standard treatment for locally advanced rectal cancer . | [
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Induction Chemotherapy Reduces Patient-reported Toxicities During Neoadjuvant ... |
64dae357e4b90c9b29bcfa07ba6af307 | Prior to the procedure , the child was administered a dental cocktail containing chloral hydrate , hydroxyzine , and methadone . | [
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A fatality due to an accidental methadone substitution in a dental cocktail. A... |
e447b67e96d1d9d23058ebfd3961dda4 | We aimed to compare the effect of four TK inhibitors ( axitinib , sunitinib , vandetanib , and XL184 ) on cell proliferation , RET expression and autophosphorylation , and ERK activation in cell lines expressing a MEN2A ( MTC-TT ) , a MEN2B ( MZ-CRC-1 ) mutation , and a RET/PTC ( TPC-1 ) rearrangement . | [
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... | [] | The effects of four different tyrosine kinase inhibitors on medullary and papillary thyroid cancer cells. Medullary and papillary thyroid carcinoma (MTC and PTC) are two types of thyroid cancer that can originate from activating mutations or rearrangements in the RET gene. Therapeutic options are limited in recurrent d... | https://pubmed.ncbi.nlm.nih.gov/21470995/ | ### Instruction:
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The effects of four different tyrosine kinase inhibitors on medullary and papi... |
27860521bbec4e5bd55327f4454516d5 | Additive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia . | [
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Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
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Additive beneficial effects of fenofibrate combined with atorvastatin in the t... |
88854df818fcc017ecd02baae0d05e44 | S. sciuri exhibited pronounced multiresistance , and many isolates were characterised by the carriage of a number of uncommon (multi)resistance genes ( e.g. cfr , apmA , fexA ) and decreased susceptibility towards last resort antibiotics such as linezolid and daptomycin . | [
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] | [] | Antibiotic resistance profiles of coagulase-negative staphylococci in livestock environments. Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) have globally emerged in animal husbandry. In addition to methicillin resistance, LA-MRSA may carry a variety of novel and uncommon antimicrobial resis... | https://pubmed.ncbi.nlm.nih.gov/27185355/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
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Antibiotic resistance profiles of coagulase-negative staphylococci in livestoc... |
6aa114c00b52be0ae72ee4e00cecdb8e | The results showed that chlorhexidine ( 0.5 mM ) was more effective than benzalkonium chloride ( 1 mM ) and piperazine ( 1 mM ) . | [
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The effect of some cationic antiseptics on the acidogenicity of dental plaque ... |
6ea354435c312ec5e44e62fe484b70f8 | Finally , although anidulafungin ( as an echinocandin surrogate susceptibility marker ) and amphotericin B ECVs should identify Candida and Aspergillus isolates with reduced susceptibility to these agents using the Etest , these ECVs will not categorize a fungal isolate as susceptible or resistant , as breakpoints do . | [
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Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
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Multicenter Study of Method-Dependent Epidemiological Cutoff Values for Detect... |
39b25cd9d4e2b993067672f328365fae | The method decision limits were determined to be 1.27 and 0.59 microg/kg for erythromycin and tylosin , respectively . | [
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] | [] | Determination of erythromycin and tylosin residues in honey by LC/MS/MS. Antibiotics are used in apiculture to protect bees against a variety of brood diseases. As a result of the development of resistance to oxytetracycline, erythromycin and tylosin are increasingly used for the prevention and treatment of these disea... | https://pubmed.ncbi.nlm.nih.gov/19610392/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
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Determination of erythromycin and tylosin residues in honey by LC/MS/MS. Antib... |
92e3dc3dddb96036451c1e9b0f351877 | Bevacizumab with or without erlotinib as maintenance therapy in patients with metastatic colorectal cancer ( GERCOR DREAM ; OPTIMOX3 ): a randomised , open-label , phase 3 trial . | [
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8992547ade8ad225056deedabff483df | Eighteen patients with primary or recurrent ovarian cancer were treated with paclitaxel 150 or 110 mg/m2 , respectively , together with gemcitabine 800 mg/m2 and cisplatin 75 mg/m2 , 3 weekly for 6 cycles . | [
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8e02adf7ef7e1034f79edf03487bc95b | After pretreatment with warfarin ( 0.2 mg/kg/day ) , low-dose rivaroxaban ( 60 mg/kg/day ) , high-dose rivaroxaban ( 120 mg/kg/day ) , or vehicle for 14 days , transient middle cerebral artery occlusion was induced for 90 min , followed by reperfusion with tPA ( 10 mg/kg/10 ml ) . | [
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20b7ca4fb30c58b4314d757911531693 | The cost-minimisation analysis showed that treatment costs for a 12-week course of capecitabine ( Pounds 2132 ) and tegafur with uracil ( Pounds 3385 ) were lower than costs for the intravenous Mayo regimen ( Pounds 3593 ) and infusional regimens on the de Gramont ( Pounds 6255 ) and Modified de Gramont ( Pounds 3485 )... | [
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The clinical and economic benefits of capecitabine and tegafur with uracil in ... |
07a90e10a5261b7008e02cead48838c6 | However , the combination of clindamycin and ciprofloxacin increased mortality associated with B. anthracis Sterne infection , particularly in gamma-irradiated animals . | [
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f5a4e1a3a2fd7c354cb27e3be2de987c | We investigated the maximum tolerated dose , dose-limiting toxicities , and response rate when the selective cyclooxygenase-2 inhibitor celecoxib is added to concurrent irinotecan , cisplatin , and radiation therapy for patients with inoperable stage II-III non-small cell lung cancer ( NSCLC ) . | [
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a928f7c6c1f1afb1f3997fc61a95654f | The combination of docetaxel and estramustine phosphate ( estramustine ) has been reported to be effective for HRPC . | [
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c46f91136c37afe4ed955420e39cc87a | Significant advances have been made in the last decade since the introduction of different tyrosine kinase inhibitors ( TKIs ) such as sunitinib , pazopanib , and sorafenib . | [
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"start": ... | [] | First-line tyrosine kinase inhibitors in metastatic renal cell carcinoma: A regional cancer center experience. Renal cell carcinoma (RCC) is highly resistant to systemic chemotherapy, and historically a poor prognosis for metastatic disease has been reported, with a 5-year survival rate of <10%. Significant advances ha... | https://pubmed.ncbi.nlm.nih.gov/30082547/ | ### Instruction:
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1d45a41a4087429135570126b747b54e | A fixed-dose combination of artesunate + amodiaquine ( ASAQ ) was recently developed . | [
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0da184f3d08d17f701d7a11270065b3e | All patients have received a median of four and half cycles ( range , 1 - 10 ) of 3-week ( 60 - 75 mg/m2 ) docetaxel regimens and 5 mg prednisone twice per day . | [
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7ad567a67c448d2d87998e69080f20fb | Combination therapy with other agents including anticoagulants , antihypertensive , anti-inflammatory , oral hypoglycemic and antifungal agents as well as beta-blockers , H2 blockers , cyclosporine and digoxin has been also reviewed . | [
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dc325ea5ead86b3a17c5f4b4f215509b | Comparative study of tranexamic acid and norethisterone in the treatment of ovulatory menorrhagia . | [
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Comparative study of tranexamic acid and norethisterone in the treatment of ov... |
97e1c88327c1ea59d0837ea5a5433a97 | The results of this work encourage the in vivo examination of the therapeutic potential of the combination of bortezomib and rapamycin in Mantle Cell Lymphoma patients . | [
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The effect of Bortezomib and Rapamycin on Telomerase Activity in Mantle Cell L... |
3e99a850beac024e20cc6bb5376f01de | Additive effects of combined valsartan and spironolactone on cardiac aldosterone escape in spontaneously hypertensive rats . | [
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Additive effects of combined valsartan and spironolactone on cardiac aldostero... |
206efdfddbfc96d10d86fbfe7dea73ae | 54 patients without distant metastases ( T2-T3b , N0-X , M0 ) received 3 cycles of neoadjuvant chemotherapy according to the MVAC protocol ( methotrexate , vinblastine , doxorubicin and cisplatin ) after transurethral resection ( TUR ) followed by cystectomy . | [
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82d01675243026c612a8cdb0a49b6a38 | The objective of this study was to compare cycle control , efficacy and tolerance of an oral contraceptive containing 20 microg ethinylestradiol and 150 microg desogestrel with a preparation containing 30 microg ethinylestradiol combined with 75 microg gestodene . | [
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Latin american experience with two low-dose oral contraceptives containing 30 ... |
22442dbeede668f6698d00b04a0b5e72 | They were assigned to either receiving a COCP containing 20 mcg ethinyl estradiol/150 mg desogestrel for two continuous cycle or NSAID ; mefenamic acid 500 mg TDS for 5 days , 21 days apart for two cycles . | [
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a5c80ba5bf5b384aa07401174cdc1726 | Preclinical data suggest that enzastaurin and bevacizumab may have complementary effects in inhibiting angiogenesis . | [
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64476c3ec43afe5a97fb58f0c495f642 | The PASI-75 , -90 and -100 were the highest in secukinumab ( 91.3 % , 82.6 % , 41.3 % , respectively ) , followed by ustekinumab ( 79.6 % , 44.9 % , 16.3 % ) , adalimumab ( 64.3 % , 28.6 % , 7.1 % ) and etanercept ( 50.0 % , 30.0 % , 0 % ) . | [
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502832b2d66be4f7c76573ad6f1b15dc | Trials have demonstrated decreased relapse with perioperative methotrexate , vinblastine , doxorubicin and cisplatin ( M-VAC ) chemotherapy in patients with muscle invasive bladder cancer . | [
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2e405044ef34961a85c429587014c801 | m2 on day 1 , oxaliplatin 85 mg/m² day 1 and capecitabine twice-daily dose of 625 mg/ m2 , p.o . for 2 weeks ) every 3 | [
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A Modified Epirubicin and Oxaliplatin Plus Capecitabine (EOX) Regimen as a Sec... |
60e477e5cd5aded203a0a848439207a0 | The objective of this analysis was to assess the cost-effectiveness of risedronate compared to generic alendronate in Germany applying the REAL effectiveness data . | [
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The impact of fewer hip fractures with risedronate versus alendronate in the f... |
5d8e94d769dadafed1e67a36606f7721 | However , two phase III trials demonstrated that incorporation of oxaliplatin to capecitabine with RT did not improve early outcomes and , by contrast , increased toxicity . | [
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The role of capecitabine in locally advanced rectal cancer treatment: an updat... |
677fdeeb41810fb495dcbcc5969fcc98 | The addition of everolimus to bicalutamide treatment of resistant tumours significantly reduced tumour growth rates and tumour volumes . | [
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Prolonging hormone sensitivity in prostate cancer xenografts through dual inhi... |
503a43e79ed74f42ff3b6fe92e2e4472 | Ropivacaine and bupivacaine were the common drugs used for RA , which were independent of RA utilization . | [
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085af6dcbceb17f4d6d9007c05ca030d | In 13 patients treated with equivalent doses of rotigotine switched from other DAs ( pramipexole , ropinirole , and cabergoline ) , ESS did not increase after treatment ( 10.0 ± 4.6 before and 8.6 ± 4.5 after treatment ) and decreased without worsening of CGI-I in 54 % patients . | [
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"start": 99... | [] | Rotigotine Transdermal Patch Does Not Make Parkinson Disease Patients Sleepy During Daytime. To assess quantitatively the influence of rotigotine transdermal patch on daytime sleepiness, the most common adverse event by non-ergot dopamine agonists (DAs), in Parkinson disease (PD) patients. ### methods An open-label stu... | https://pubmed.ncbi.nlm.nih.gov/26536020/ | ### Instruction:
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Rotigotine Transdermal Patch Does Not Make Parkinson Disease Patients Sleepy D... |
2f80aa3ed0868deba396a0cbaf76b31f | To assess plasma steady-state pharmacokinetics ( PK ) of rifampicin , isoniazid , saquinavir and ritonavir in HIV and tuberculosis ( TB ) co-infected patients , and investigate potential interactions between TB drugs and protease inhibitors ( PIs ) . | [
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Pharmacokinetic interaction between rifampicin and the once-daily combination ... |
08a35fc86bac0d38e3375f9b88b26dd4 | We randomly assigned 808 patients with HER2-positive metastatic breast cancer to receive placebo plus trastuzumab plus docetaxel ( control group ) or pertuzumab plus trastuzumab plus docetaxel ( pertuzumab group ) as first-line treatment until the time of disease progression or the development of toxic effects that cou... | [
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Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. The a... |
c2679a7e1f713326ad184919894b6e1c | Toxicological studies revealed that the oral LD50 for thiabendazole in mice was 2200 mg/kg , and when combined with 140 mg/kg of aspirin , the LD50 was reduced to 900 mg/kg . | [
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The effect of thiabendazole on pain threshold. thiabendazole significantly inc... |
a9b18b3c6a9e25a33609280998e2412d | Azacitidine and enasidenib are two therapies available for treatment of acute myelogenous leukemia ( AML ) , and the mechanisms of action of these drugs involve alteration of aberrant DNA methylation . | [
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Combination of azacitidine and enasidenib enhances leukemic cell differentiati... |
8c910778beeef8e539f66fd377e27eeb | Good , moderate and mild pain relief were noted in 19 ( 41 % ) , six ( 13 % ) and seven ( 15 % ) patients on lamotrigine and 13 ( 28 % ) , five ( 11 % ) and 15 ( 33 % ) patients on amitriptyline , respectively , by patient 's global assessment of efficacy and safety . | [
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Randomized double-blind study comparing the efficacy and safety of lamotrigine... |
e3eaa19866764043fe913227f0c1329f | The majority of the evidence comes from studies of bevacizumab and triamcinolone used as primary therapy for DMO . | [
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Anti-vascular endothelial growth factor combined with intravitreal steroids fo... |
8d3aa3b09931b7d3aa9d1b62ecf79b24 | Doxorubicin and ifosfamide are currently the two main drugs for the treatment of soft tissue sarcomas in adults . | [
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Perspectives on anthracyclines plus ifosfamide in advanced soft tissue sarcoma... |
dff2572ca5c7f865279efd425491fe4b | The skin and oral mucous membrane lesions recurred after effective treatments with methylprednisolone pulse therapy and combination therapy with prednisolone and cyclosporine . | [
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Successful treatment of adolescent pemphigus vulgaris by immunoadsorption meth... |
b9e3bc7f24bf72f23bc8e89b71cbd677 | Incorporation of colistin significantly accelerated the release of ciprofloxacin from the DMPG anionic liposomes . | [
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Co-Delivery of Ciprofloxacin and Colistin in Liposomal Formulations with Enhan... |
b0b756e4eaeb1d41e01248091673c2d5 | MAB using flutamide as second-line hormonal therapy can give a comparatively favourable PSA response with no severe side-effects ; therefore , this therapy may be suitable for patients with HRPC after primary MAB using bicalutamide has failed , particularly in those with no bone metastases or whose disease has progress... | [
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Clinical outcome of maximum androgen blockade using flutamide as second-line h... |
c5056778116a14b966bbe222b32e1acb | Phase I study of decitabine in combination with vorinostat in patients with advanced solid tumors and non-Hodgkin 's lymphomas . | [
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Phase I study of decitabine in combination with vorinostat in patients with ad... |
43af8a23a61c911f4823dbc4f666bac8 | Epirubicin ( 35 mg/m(2 ) ) and cyclophosphamide ( 400 mg/m(2 ) ) were administered from day 2 to day 4 , every 4 weeks . | [
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Combined 5-fluorouracil infusion with fractionated epirubicin and cyclophospha... |
c4003c230fdd89dca38ff9d23a7fdbb1 | Our patient could be weaned from LVAD probably due to the combination management strategy employing mitral valvuloplasty , use of cardiac resynchronization therapy , and taking carvedilol with spironolactone . | [
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Successful bridge to recovery with VAD implantation for anthracycline-induced ... |
8d4b14787de8987d0a9a17e167f7aeec | Serum hydroxyzine and cetirizine concentrations were above the limit of quantitation ( 0.1 ng/ml ) of the assay | [
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Pharmacokinetics of hydroxyzine and cetirizine following oral administration o... |
9443916aa7d28a5adeec2d2386bee04d | Although well tolerated , the efficacy of everolimus and vinorelbine combination therapy was not superior to vinorelbine monotherapy . | [
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VicTORia: a randomised phase II study to compare vinorelbine in combination wi... |
eb3681c71c2520fe8ab1a0369e10b461 | In addition , our results suggested that adalimumab , tocilizumab , rituximab and glucocorticoids may also have beneficial effects in restoring normal transcriptome , but not chloroquine , hydroxychloroquine or interferons . | [
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... | [] | Transcriptomic signatures and repurposing drugs for COVID-19 patients: findings of bioinformatics analyses. The novel coronavirus SARS-CoV-2 is damaging the world's social and economic fabrics seriously. Effective drugs are urgently needed to decrease the high mortality rate of COVID-19 patients. Unfortunately, effecti... | https://pubmed.ncbi.nlm.nih.gov/33312453/ | ### Instruction:
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Transcriptomic signatures and repurposing drugs for COVID-19 patients: finding... |
cfb44c26cc0a1b85c41cf38e39dac79a | In addition , biochemical examinations revealed that docetaxel could induce phosphorylation of both bcl-2 and c-raf-1 , but these changes were inhibited when tumor cells were pretreated or simultaneously treated with doxorubicin . | [
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In vitro evaluation of schedule-dependent interactions between docetaxel and d... |
168b963c3be6ac1ded38c2d41bc9b197 | Enhancement of radiation-induced downstaging of rectal cancer by fluorouracil and high-dose leucovorin chemotherapy . | [
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"start": 65,
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{
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"text": "leucovorin",
"start": 92,
"end": 102,
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] | [
{
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] | Enhancement of radiation-induced downstaging of rectal cancer by fluorouracil and high-dose leucovorin chemotherapy . To determine if fluorouracil (5-FU) plus high-dose leucovorin (LV) enhances local response in patients receiving preoperative radiation therapy (RT) for adenocarcinoma of the rectum, we compared the deg... | https://pubmed.ncbi.nlm.nih.gov/1727928/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
Enhancement of radiation-induced downstaging of rectal cancer by fluorouracil ... |
121a385260e78585b9b54b3081ebe872 | Final analysis of a phase II study of nivolumab in combination with ipilimumab for unresectable chemotherapy-naive advanced melanoma . | [
{
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{
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] | Final analysis of a phase II study of nivolumab in combination with ipilimumab for unresectable chemotherapy-naive advanced melanoma . nivolumab plus ipilimumab combination is currently one of the preferred regimens for advanced melanoma in recently updated clinical practice guidelines. However, the evidence on the eff... | https://pubmed.ncbi.nlm.nih.gov/32812243/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
Final analysis of a phase II study of nivolumab in combination with ipilimumab... |
bfc860242fe9e9abc5f6ea5ffa6f1122 | In some relatively developed regions in China , infliximab and rituximab may be a favorable cost-effective alternative for moderate to severe RA . | [
{
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{
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"start": 63,
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{
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] | Cost effectiveness of different treatment strategies in the treatment of patients with moderate to severe rheumatoid arthritis in china. To analyse the cost-effectiveness of traditional disease-modifying anti-rheumatic drugs (tDMARDs) compared to biological therapies from the perspective of Chinese society. ### Methodo... | https://pubmed.ncbi.nlm.nih.gov/23056637/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
Cost effectiveness of different treatment strategies in the treatment of patie... |
0b928797b63ebfe5e343e20167824e7c | Topiramate CR treatment produced significant weight loss and meaningful improvements in A1C and blood pressure in obese patients with type 2 diabetes treated with diet and exercise or in combination with metformin . | [
{
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{
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"start": 204,
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{
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] | A randomized, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of topiramate controlled release in the treatment of obese type 2 diabetic patients. This is a randomized, placebo-controlled study of the weight-loss efficacy and safety of a controlled-release (CR) formulation of topir... | https://pubmed.ncbi.nlm.nih.gov/17363756/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
A randomized, double-blind, placebo-controlled, multicenter study to assess th... |
b9dfb483cf8d157dbce9404de8005b7c | To compare efficacy and toxicity of bolus application of chemotherapy protocol , oxaliplatin , fluorouracil ( bolus ) , leucovorin ( folfox ) between two groups of patients in the therapy of metastatic colorectal carcinoma ( mCRC ) . | [
{
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{
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{
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"start... | [
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] | Therapeutic efficacy and toxicity of bolus application of chemotherapy protocol in the treatment of metastatic colorectal cancer. To compare efficacy and toxicity of bolus application of chemotherapy protocol , oxaliplatin , fluorouracil ( bolus ) , leucovorin ( folfox ) between two groups of patients in the therapy o... | https://pubmed.ncbi.nlm.nih.gov/26276661/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
Therapeutic efficacy and toxicity of bolus application of chemotherapy protoco... |
9075a075ca48e05ac8a70fe6bf5e903d | Verapamil and quinine were added in patients with tumors failing to respond or progressing on CVAD alone . | [
{
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{
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"token_start": 2,
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] | [
{
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] | Combination chemotherapy with cyclophosphamide, vincristine, adriamycin, and dexamethasone (CVAD) plus oral quinine and verapamil in patients with advanced breast cancer. We evaluated the question of whether the chemosensitizers verapamil and quinine given orally to breast cancer patients failing combination chemothera... | https://pubmed.ncbi.nlm.nih.gov/9116320/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
Combination chemotherapy with cyclophosphamide, vincristine, adriamycin, and d... |
b01ddd458e6d0f844ef2a2dabc1e9c0d | However , dipyridamole had no effect on both the influx and efflux of epirubicin in doxorubicin-sensitive cells . | [
{
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{
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] | [
{
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] | [Studies on reversing effect of multidrug resistance by dipyridamole. II. Inhibition of epirubicin efflux from resistant cells by dipyridamole and its pharmacological effect]. We have previously reported that dipyridamole increases the cytotoxicity of epirubicin and alters the cell cycle in doxorubicin-resistant (P388/... | https://pubmed.ncbi.nlm.nih.gov/8721351/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
[Studies on reversing effect of multidrug resistance by dipyridamole. II. Inhi... |
acbfe42000da2810b6325717404141e6 | This study aims to evaluate the potential role of combination therapy with docetaxel , flavopiridol , or 5-FU in modulating chemosensitivity and better understand how they might be used clinically . | [
{
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"start": 75,
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{
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"start": 87,
"end": 99,
"token_start": 14,
"token_end": 15
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] | [
{
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] | Efficacy of sequential treatment of HCT116 colon cancer monolayers and xenografts with docetaxel, flavopiridol, and 5-fluorouracil. Clinical treatment of solid tumors with docetaxel, flavopiridol, or 5-fluorouracil (5-FU) often encounters undesirable side effects and drug resistance. This study aims to evaluate the pot... | https://pubmed.ncbi.nlm.nih.gov/17007746/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
Efficacy of sequential treatment of HCT116 colon cancer monolayers and xenogra... |
caa3da2a86157dc41125f56205a1a5d4 | Dipyridamole or dipyridamole and acetylsalicyclic acid were used in 22 pregnancies . | [
{
"span_id": 0,
"text": "Dipyridamole",
"start": 0,
"end": 12,
"token_start": 0,
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{
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"start": 16,
"end": 28,
"token_start": 2,
"token_end": 3
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{
"span_id": 2,
"text": "acetylsalicyclic acid",
... | [
{
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"spans": [
1,
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] | The course of pregnancy in patients with artificial heart valves. Twenty-five women with prosthetic heart valves (PHV) became pregnant 28 times. Twenty-six of the pregnancies occurred while the patients were receiving oral anticoagulants and these were continued throughout in 25 pregnancies. Dipyridamole or dipyridamol... | https://pubmed.ncbi.nlm.nih.gov/973644/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
The course of pregnancy in patients with artificial heart valves. Twenty-five ... |
ea455dd922639a395f7675d9beb480a2 | Bevacizumab and trastuzumab are efficacious for treatment of advanced or HER2-positive metastatic breast cancer ; however , few data exist for this regimen in inflammatory breast cancer . | [
{
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{
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"token_start": 2,
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] | [
{
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] | Neoadjuvant bevacizumab, trastuzumab, and chemotherapy for primary inflammatory HER2-positive breast cancer (BEVERLY-2): an open-label, single-arm phase 2 study. Bevacizumab and trastuzumab are efficacious for treatment of advanced or HER2-positive metastatic breast cancer ; however , few data exist for this regimen i... | https://pubmed.ncbi.nlm.nih.gov/22377126/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
Neoadjuvant bevacizumab, trastuzumab, and chemotherapy for primary inflammator... |
17a298de5c61f56d978d1ac05164d0d5 | The frequency of their resistance to penicillin and ampicillin was 76.8 % ( 159/207 ) , followed by erythromycin ( 56 % , 116/207 ) , trimethoprim-sulfamethoxazole ( 28.5 % , 59/207 ) , chloramphenicol ( 24.2 % , 50/207 ) , kanamycin ( 19.8 % , 41/207 ) , and doxycycline ( 1.4 % , 3/207 ) . | [
{
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"token_start": 8,
"token_end": 9
},
{
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"text": "erythromycin",
"start": 100,
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"token_start": 18,
"token_end": 19
},
{
"span_id": 2,
"text": "chloramphenicol",
"st... | [] | Antimicrobial susceptibilities of exfoliative toxigenic and non-toxigenic Staphylococcus hyicus strains in Japan. Staphylococcus hyicus isolates (n=207), including 150 exfolitative toxigenic and 57 non-toxigenic strains, were examined for their susceptibility to 13 antimicrobial agents by using the dehydrated 96-well M... | https://pubmed.ncbi.nlm.nih.gov/19498301/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
Antimicrobial susceptibilities of exfoliative toxigenic and non-toxigenic Stap... |
7a43db7cf232e74d3891f1026462d914 | Rats were distributed into three groups ( n = 5 ) according to the drug studied namely , 50 % enantiomeric excess bupivacaine mixture ( 5 μg/mL ) ; pancuronium ( 2 μg/mL ) ; 50 % enantiomeric excess bupivacaine mixture + pancuronium . | [
{
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"text": "bupivacaine",
"start": 114,
"end": 125,
"token_start": 22,
"token_end": 23
},
{
"span_id": 1,
"text": "pancuronium",
"start": 148,
"end": 159,
"token_start": 29,
"token_end": 30
},
{
"span_id": 2,
"text": "bupivacaine",
"st... | [
{
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"is_context_needed": true
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] | Effect of 50% enantiomeric excess bupivacaine mixture combined with pancuronium on neuromuscular transmission in rat phrenic nerve-diaphragm preparation; a pilot study. Local anaesthetics are drugs that are widely used in clinical practice. However, the effects of these drugs on the neuromuscular junction and their inf... | https://pubmed.ncbi.nlm.nih.gov/26755834/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
Effect of 50% enantiomeric excess bupivacaine mixture combined with pancuroniu... |
fff07e1e94c80840f59c9458ee5f7de2 | Blood was sampled immediately prior to premedication ( temazepam ) , after induction of anaesthesia ( fentanyl and thiopentone ) and at 10-minute intervals until the end of the procedure ( N2O maintenance , vecuronium relaxation ) . | [
{
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"text": "temazepam",
"start": 55,
"end": 64,
"token_start": 8,
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},
{
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"text": "fentanyl",
"start": 102,
"end": 110,
"token_start": 16,
"token_end": 17
},
{
"span_id": 2,
"text": "thiopentone",
"start": 115... | [
{
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"spans": [
0,
1,
2,
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] | The plasma ACTH, AVP, CRH and catecholamine responses to conventional and laparoscopic cholecystectomy. We compared the responses of the stress hormones, cortisol, ACTH, vasopressin (AVP), corticotrophin releasing hormone (CRH) and catecholamines to elective conventional and laparoscopic cholecystectomy. ### design A r... | https://pubmed.ncbi.nlm.nih.gov/8392916/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
The plasma ACTH, AVP, CRH and catecholamine responses to conventional and lapa... |
f953f0ee4e567cff2bf69362b2ed6d37 | This study was performed to compare the efficacy of peritonsillar infiltration of bupivacaine , tramadol and combination of bupivacaine-tramadol in post-tonsillectomy pain . | [
{
"span_id": 0,
"text": "bupivacaine",
"start": 82,
"end": 93,
"token_start": 12,
"token_end": 13
},
{
"span_id": 1,
"text": "tramadol",
"start": 96,
"end": 104,
"token_start": 14,
"token_end": 15
}
] | [] | Preemptive peritonsillar infiltration with bupivacaine in combination with tramadol improves pediatric post-tonsillectomy pain better than using bupivacaine or tramadol alone: A randomized, placebo-controlled, double blind clinical trial. Post-tonsillectomy pain is one of the most common problems after anesthesia, ther... | https://pubmed.ncbi.nlm.nih.gov/26322280/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
Preemptive peritonsillar infiltration with bupivacaine in combination with tra... |
4dd39ba2d55cff79d702f364d08a7ac0 | The planned concomitant treatment in group B was : bleomycin 5 units twice a week i.m . , total dose 70 units , mitomycin C 15 mg/m2 i.v . after delivery of 10 Gy , and 10 mg/m2 i.v . on the last day of radiotherapy . | [
{
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"start": 51,
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"token_start": 9,
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},
{
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"text": "mitomycin",
"start": 112,
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"token_end": 24
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] | [
{
"class": "POS",
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] | Concomitant radiotherapy with mitomycin C and bleomycin compared with radiotherapy alone in inoperable head and neck cancer: final report. To compare the efficacy of concomitant irradiation with mitomycin C and bleomycin in patients with inoperable head and neck carcinoma with radiotherapy alone. ### Methods And Materi... | https://pubmed.ncbi.nlm.nih.gov/9719123/ | ### Instruction:
Given the context about compound efficacy for the given treatment mentioned within the input, mentioned the compounds
that can co-occur for the mentioned treatment
### Input:
Concomitant radiotherapy with mitomycin C and bleomycin compared with radiothe... |
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