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135
2ff28d81-b1dc-4b5c-9ad8-1587b75864cd
Waves present in electroretinogram are all EXCEPT:
a wave
bwave
c wave
d wave
3d
multi
ANSWER: (D) d waveREF: Khurana 4th ed p. 489Electroretinogram is composed of:a wave : Rods and Conesb wave : Muller cellsc wave: Pigment epithelium
Ophthalmology
Neuro-Ophthalmology
8a7f180a-d10e-4b2b-ae57-3cc6e97f022a
Rapid diffusion of water across cell membranes depends on the presence of water channels, called aquaporins. Proximal convoluted tubule have:
Aquaporin 1
Aquaporin 2
Aquaporin 5
Aquaporin 9
0a
multi
Aquaporin-1 is localized to both the basolateral and apical membrane of the proximal tubules and its presence allows water to move rapidly out of the tubule along the osmotic gradients set up by active transpo of solutes, and isotonicity is maintained. Ref: Barrett K.E., Barman S.M., Boitano S., Brooks H.L. (2012). Cha...
Physiology
null
659d8fb4-e1d8-4fbd-a09a-b08cb36b0cbf
E.H. Angle introduced his classification of malocclusion in:
1876
1900
1899
1903
2c
single
ANGLE'S CLASSIFICATION OF MALOCCLUSION In 1899, Edward Angle classified malocclusion based on the mesial-distal relation of the teeth, dental arches and jaws. He considered the maxillary first permanent molar as a fixed anatomical point in the jaws and the key to occlusion. Ref: Textbook of orthodontics Gurkeerat Singh 2n...
Dental
null
608b0c0c-74a3-48c2-92b3-f59e98d2a7e8
Histiocytes are:
Scavenger cells
Allergic cells
Released in immunologic response
Leukocytes
0a
multi
null
Physiology
null
7a603add-33a7-4a96-a9a9-f72b482cb41c
How much is the probable bilirubin level of this neonate?
6 mg/dl
9 mg/dl
12 mg/dl
18 mg/dl
3d
single
Yellow staining of palms & soles indicates a bilirubin level > 15 mg/dl Modified Kramer rule:
Pediatrics
Neonatal Jaundice
b463fe87-c185-4ce8-ad60-ffe951a07db5
A patient with glaucoma is being treated with systemic beta blocker. All of the foll,twing can be given to the patient except
Brimonidine
Dorzolamide
Levobunolol
Prostaglandin
2c
multi
Ans. c. Levobunolol Brimonidine, dorzolamide and prostaglandin are topical anti-glaucoma drugs. These drugs do not have systemic side effects, while levobunolol (beta-blocker) is systemic anti-glaucoma drug given orally, having systemic side effects. That is why in patients with glaucoma treated with systemic beta bloc...
Pharmacology
null
8c7f6285-ce04-44cd-a9ca-24e52bacacb1
Not a mechanism of Action of Insulin
Tyrosine kinase-beta cell stimulation
Incroporation of GLUT-4 into cells
Inhibition of Na+K+ATPase
Hexokinase stimulation
2c
single
INSULIN is a protein hormone formed from proinsulin in the beta cells of the pancreatic islets of Langerhans. The major fuel-regulating hormone, it is secreted into the blood in response to a rise in concentration of blood glucose or amino acids. Insulin promotes the storage of glucose and the uptake of amino acids, in...
Physiology
Endocrinology
d7278944-1a25-4859-bf55-01600c4ae421
In carcinoma prostate with matastasis which is raised
ESR
Alkaline phosphatase
Acid phosphatase
Bilirubin
1b
single
null
Surgery
null
fd933c85-c0b4-4be4-bf69-f0b27ccc3848
Inhibitor of Complex I of ETC-
H2S
2, 4 DND
Rotenone
BAL
2c
multi
Ans. is 'c' i.e., Rotenone Inhibitors of Electron transport chain (Respiratory chain)o Complex I:- Barbiturates (amoborbital), piercidin A, rotenone, ehlorpromazine, guanithidine.o Complex II:- Carboxin, TTFA, malonate.o Complex III:- Dimercaprol, BAL, actinomycin A, Naphthyloquinone.o Complex IV (cytochrome c oxidase)...
Biochemistry
Respiratory Chain
cadae1b1-a5cb-49f9-b6fd-33c81ae6682f
Diuretics that can be used in renal failure is -
Furosetnide
Chlohiazide
Mannitol
Chlohalidone
0a
single
Ans. is 'a' i.e., Furosemide Loop diuretics (furosemide) can be used in renal failure. Among thiazides, only metolazone is used in renal failure.
Pharmacology
null
3ddd6157-7227-41bd-a5d6-81fa79f20418
patient is known case of CAD suddenly presents with chest pain , shoness of breath, and with blood pressure of 90/60mmhg o/e cold clammy skin is observed, with urine output of 25ml/hr .what is the drug of choice ?
droxidopa
adrenaline
dopamine
dobutamine
2c
single
Cardiogenic shock is a condition in which your hea suddenly can&;t pump enough blood to meet your body&;s needs. The condition is most often caused by a csevere hea attack. Angina Pectoris, squeezing pain in center of chest. # Dysrhythmias * Diminished hea sounds * Acute drop in blood pressure > 30 mm Hg * Decreased ca...
Pharmacology
All India exam
55d899f1-0d0d-434f-acc5-377cf098be0d
Neoadjuvant chemotherapy stands for -
Chemotherapy along with surgery
Chemotherapy before surgery
Chemotherapy after surgery
Chemotherapy along with radiation therapy
1b
single
Ans. B. Chemotherapy before surgeryNeoadiuvant chemotherapy refers to Combination of Chemotherapy and surgery/radiotherapy in which chemotherapy is given prior to surgery/radiotherapy.
Radiology
null
5a5817da-ca1f-4653-ba95-4e5287095a3f
Flowing wax appearance on anterior and posterior borders of vertebrae with normal intervertebral disc space occurring due to ligament calcification is seen in –
Ankylosing spondylitis
Diffuse idiopathic skeletal hypertrophy
Psoriatic spondyloarthropathy
RA
1b
single
Diffuse idiopathic skeletal hyperostosis: DISH (hyperostotic spondylosis, Forestier's disease) is a multifocal entity of older people characterized by "flowing ossifications of the spine" involving four or more contiguous vertebrae and hyperostosis of some ligamentous attachments. The thick, flowing, florid, exuberant ...
Radiology
null
3e9d6544-e024-4e4d-bda0-e99f176502f6
Which is false about hemolytic anemia?
Decreased LDH
Decreased Haptoglobin
Decreased RBC survival
Increased Uncongugated Bilirubin
0a
multi
Ans. (a) Decreased LDH(Ref: 9th/pg 631-632)In hemolytic anemia, there is decreased haptoglobin, decreased RBC survival, increased unconjugated bilirubin & Increased LDH.
Pathology
Misc. (R.B.C)
0b486244-a2f0-40f5-92d3-b018dd85e760
Oligohydramnios is seen in -
Renal agenesis
Oesophageal atresia
Exomphalos
Neural tube defect
0a
single
Ans. is 'a' i.e. Renal agenesis Renal agenesis prevents urine formation which leads to oligohydramnios.Oligohydramnios is condition where amniotic fluid is deficient in amount to the extent of 100ml or entirely absentAetiologyRenal agenesis*Amnion nodosum*IUGR*Post maturity*Obst. of urinary tract (post urethral Valve*)
Gynaecology & Obstetrics
Hydramnios and Oligo Hydramnios
06db2902-3592-4f74-acb6-f4f9d01a1635
Dermatome supplying the middle finger is-
C6
C7
C8
T1
1b
single
Ans. is 'b' i.e., C7 * Sensory distribution of upper limb is as followThe cutaneous nervesRegion suppliedNerve(s)Root valueDerived fromUpper part of pectoral region, and skin over upper part of deltoidSupraclavicularC3,C4Cervical plexusArm 1. Upper medial partIntercostobrachialT22nd intercostal2. Lower medial partMedia...
Anatomy
Upper Extremity
65f3144c-1d8b-480e-bdc7-b18e4dfa4d96
A 10 year old boy is having hypeension. There is no other significant history and urine analysis is cause for his hypeension ?
Chronic glomerulonephritis
Polycystic kidney disease
Reflux nephropathy
Renal Parenchymal disease
1b
single
All these renal disease leads to hypeension. But except in polycystic kidney disease, all other will show characteristics urine findings. Polycystic kidney disease is usually asymptotic. Hypeension devolops about 10 to 20 years of age. Reference: GHAI Essential pediatrics, 8th edition
Pediatrics
C.V.S
ccef4d75-9799-4592-9555-e775093126d4
What is the mechanism of action of Fulvestrant?
Selective estrogen agonist
Selective esrogen receptor modulator
Selective esrogen receptor upregulator
Selective esrogen receptor downregulator
3d
single
Fulvestrant: is an estrogen receptor antagonist that downregulates the estrogen receptor and has no agonist effects. Fulvestrant competitively inhibits binding of oestradiol to the estrogen receptor (ER), with a binding affinity that is 89% that of oestradiol. Reduces the number of estrogen receptor. Good to know: It i...
Pharmacology
null
f4f20037-2971-4f59-9589-4bcd3666a0df
8 year old child with hematuria in 5 days after throat infection?
Post streptococcal nephropathy
Ig A nephropathy
Nephrotic syndrome
can be a or b
1b
single
Ans. is 'b'i.e., Ig A Nephnopathy IgA nephropathy Predominant deposition of IgA in glomeruli. RECURRENT episode of gross rematuria that also precipitation by UI in last 2-5 days. PSGN Acute GN following infection by group A - -hemolytic streptococci. Common in school age children. o Streptococcal infection usually of t...
Pediatrics
null
fd4d7f7f-a112-4fb5-88be-1fd5bf805297
Following is derivative of dental lamina:
Epithelial rests of Malassez
Enamel pearls
Rests of Serrae
All of the above
2c
multi
Options 'C' Rests of Serres are remnants of dental laminal epithelium entrapped within gingiva. Option 'A & B' are remnants of Hertwig epithelial root sheath.
Dental
null
c446702e-5b20-4694-937a-0951c5cc959d
Ascent to high altitude may cause all of the following except: March 2012
Cerebral edema
Pulmonary edema
Cerebral palsy
Venous thrombosis
2c
multi
Ans: C i.e. Cerebral palsyComplications of ascent to high altitudeHACE/ high altitude cerebral edema is rare, life threatening and usually preceded by AMS/ acute mountain sicknessHAPE/ high altitude pulmonary edema is a life threatening condition which usually occurs in the first 4 days after scent above 2500 m.Venous ...
Medicine
null
b523715d-b959-4929-9ae2-d0cd01aacde2
Which of the following are pathological hallmark of Alzheimer&;s disease
Intercellular Lewy Bodies
Intracellular Pick's Bodies
Extracellular Beta Amyloid Plaques
Extracellular Neurofibrillary Tangles
2c
multi
The two hallmark pathologies required for a diagnosis of Alzheimer&;s disease(AD) are the extracellular plaque deposits of the Beta-amyloid peptide (Ab) and the intracellular flame-shaped neurofibrillary tangles of the Hyper-Phophorylated microtubule binding protein &;tau&;. Histological Hallmarks of Alzheimer&;s disea...
Pathology
Nervous system
55a55d2f-2795-4614-b35e-d8335ef0fa92
Which of the following is not a cause for the development of carpal tunnel syndrome?
Alcoholism
Sarcoidosis
Gout
Menorrhagia
3d
single
Ans. is 'd' i.e., Menorrhagia * There are many causes of carpal tunnel syndrome: -1) Idiopathic: - This is the most common cause.2) Pregnancy and menopause3) Metabolic: - Gout, Diabetes mellitus4) Endocrine: - Hypothyroidism, Myxedema, Acromegaly, Hyperparathyroidism.5) Deposition disorder:- Amyloidosis, Sarcoidosis, R...
Orthopaedics
Miscellaneous
b9fd7182-d6a5-4e10-b9ef-a2f26a3a9b62
Which of the following childhood disorder improves with increase in age –
Conduct disorder
Emotional problems
Temper tantrum
Sleep disorder
2c
single
Temper tantrum reaches its peak point during second and third year of life and gradually subsides in between 3 to 6 years as the child learng to control his negativism and complies to the requests of others.
Pediatrics
null
81905da9-b211-4446-a7e1-9f957b9a5af2
Which of the following is most likely to be the cause of painful third nerve palsy of sudden onset in a man of 40
Rupture of an infraclinoid aneurysm
Sphenoidal ridge meningioma
Diabetes mellitus neuropathy
Rupture of a supraclinoid aneurysm
3d
single
Ans. Rupture of a supraclinoid aneurysm
Ophthalmology
null
180a5762-2c82-4bb7-863d-8c30659ad414
Condition in which lid is adhered to conjunctiva is-
Ankyleblepharon
Symblepharon
Trichiasis
Madarosis
1b
single
Ans. is 'b' i.e., Symblepharon * A symblepharon is a partial or complete adhesion of the palpebral conjunctiva of the eyelid to the bulbar conjunctiva of the eyeball. It results either from disease (conjunctival sequelae of trachoma) or trauma.
Ophthalmology
Lid
fa28d875-46fc-4997-9eec-0fd9c8290986
A 10 year old child due to choked suddenly on consuming food . On the failed attempt of Valsalva's manoeuvre a needle cricothyrotomywas performed . It would open into which of the following regions?
Rima glottidis
Laryngeal vestibule
Laryngeal ventricle
Infraglottic cavity
3d
single
Infraglottic cavity extends from rima glottidis to the lower border of the cricoid cailage. The rima glottidis is the space between the vocal folds and arytenoid cailages. Vestibule extends from the laryngeal inlet to the vestibular folds. Ventricle extends between vestibular fold and the vocal fold. Piriform recess is...
Anatomy
Pharynx, larynx and trachea and cranial nerves 3,4,6
82ebbe53-d8c6-42bb-8625-e5cdf1a2d7d1
The main infectious agent associated with recurrent pulmonary infections in patients with cystic fibrosis is _____________ .
Mycoplasma
Pseudomonas
Pneumocystis
Aspergilus
1b
single
Pseudomonas affect small children with malnutrition and poor immunity.it colonise airway of patients with cysticfibrosis and cause recurrent pulmonary exacerbations. pathology:well demarcated areas of consolidation and necrosis occur due to vasculitis Ref : ESSENTIAL PEDIATRICS ,O.P.GHAI, PG NO:355,7 th edition
Pediatrics
Respiratory system
110e8193-b795-4a9f-9c38-c2481b9b7e10
Pleomorphic adenoma is
More common in males
Endothelial origin
Most common site is parotid
More common in females
3d
single
null
ENT
null
81c41c9a-1d5c-4bff-b21f-f434326278d9
Which is not a product of the pentose phosphate pathway?
Sedoheptulose-7-phosphate
O2
Glyceraldehyde-3-phosphate
NADPH
1b
single
Step 5: Transketolase Reaction - Transketolase is a thiamine pyrophosphate (TPP) dependent enzyme. It transfers two-carbon unit (with keto group) from xylulose-5-phosphate to ribose-5-phosphate to form a 7 carbon sugar, sedoheptulose-7-phosphate and glyceraldehyde-3- phosphate. Transketolase enzyme will transfer the gr...
Biochemistry
Metabolism of carbohydrate
e2a6614c-8723-4dc3-8225-be6a69b2b2f1
Which is not an extrapyramidal tract -
Reticulospinal tract
Rubrospinal tract
Corticospinal tract
Tectospinal tract
2c
single
Ans. is 'c' i.e., Corticospinal tract Descending pathwaysPyramidal tractExtrapvramidal tractso Corticospinal tracto Rubrospinal tracto Tectospinal tracto Vestibulospinal tracto Reticulospinal tracto This question is a direct repeat from NBE based A1 2013-14.
Physiology
Neural Tracts
4034edd7-030e-4e74-a67b-f01c752e5fbf
In cerebellar lesion NOT seen is
Ataxia
Nystagmus
Resting tremors
Past pointing
2c
single
Resting tremor is the manifestation of parkinsonism In cerebellar lesion intentional tremors are seen
Anatomy
Neuroanatomy 1
7a57b1dc-7558-42ec-8bdb-efd1fe3be24d
A 2 yrs old boy, is brought with sudden onset of stridor and respiratory difficulty. The chest examination reveals decreased breath sounds and wheeze in the right side. The chest X-Ray showed an opaque right hemithorax. Which of the following is the most likely diagnosis:
Pneumothorax
Acute epiglottitis
Massive pleural effusion
Foreign body aspiration
3d
single
Foreign body inhalation is most common cause of acute collapse with peak age incedence in 1-2 years. Ref: Textbook of Pediatrics By K.N Agarwal, 2010, Page 235
Radiology
null
f24b6333-bc80-4b41-8db3-b91cfdb945cd
Dental caries is caused by
Streptococcus pyogenes
Streptococcus mutans
Enterococcus
Hemophilus Influenzae
1b
single
Streptococcus mutans is an alpha Hemolytic streptococcus which is a pa of the normal flora of the oral cavity. This gram-positive coccus is commonly found in the mouth from where it can spread to cause dental caries or endocarditis in individuals with risk factors(dental extraction in individuals with damaged hea valve...
Microbiology
Bacteriology
16825c90-708d-478b-bddf-641591be1105
Injury due to Alkalis causes:
Retinal detachment
Retinitis
Perforation
Symbelapharon
3d
single
Symbelapharon
Ophthalmology
null
2a4d9231-b099-44c3-a814-20aa31b23592
Massive transfusion can cause a) Hyperkalemia b) DIC c) Thrombocytopenia d) Hypothermia
a,d
b,c
a,c,d
a,b,c,d
3d
single
Complications of Massive transfusion Massive transfusion cam lead to coagulapathy and metabolic complications Most common cause of death after massive transfusion : Dilutional Coagulopathy or DIC Transfusion of 15-20 units of blood components causes Dilutional thrombocytopenia After massive transfusion initially transi...
Anatomy
General anatomy
ac09ba55-5709-43a8-88df-fe2297c17d90
Biconcave shape of RBC is useful for all, EXCEPT:
Allows considerable alteration in cell volume
Increasing surface area for diffusion
Resisting hemolysis
Passing easily through smaller capillaries
1b
multi
Biconcave shape allows easy folding of RBC on itself when it passes through capillaries. It allows considerable alteration in cell volume. Thus can withstand considerable changes of osmotic pressure and resisit hemolysis. Also Know: In humans, they survive in the circulation for an average of 120 days. The average norm...
Physiology
null
6c07ea7b-ef89-4cd9-ab60-02b483a53609
Sweating is Not present in
Heat syncope
Heat cramps
Heat stroke
Heat fatigue
2c
single
Heat stroke Exposure to high environmental temperatures can lead to following conditions ? I . Heat fatigue - Performance of a person decreases due to high environmental temperatures. The person gets tired early d/t high temp. 2. Heat cramps - these are painful spasms of voluntary muscles following strenous work in hot...
Forensic Medicine
null
262fb0cc-a4f6-44fb-a19a-354af144e281
When taking a reline impression for an upper denture, which is the most common error?
Failure to remove undercuts
Improperly rounded peripheries
Improper establishment of a post dam area
Changed centric occlusion
3d
single
null
Dental
null
48a34f28-3ee4-42ec-a8ab-21f8c98b7796
Mitral and periglomerular cells are seen in
Medulla
Olfactory bulb
Primary visual cortex
Geniculate body
1b
single
Ans. (b) Olfactory bulb(Ref: Ganong, 25th ed/p.217)Olfactory bulb has got special synaptic units called olfactory glomeruli where four types of cells are seen namely,#Mitral cells#Tufted cells#Granule cells#Periglomerular cells
Physiology
Nervous System
10c65fb9-5831-437a-9d1a-66859e4e4ba3
Osteosarcoma commonly affects: September 2005
Metaphysis
Diaphysis
Epiphysis
None of the above
0a
multi
Ans. A: Metaphysis Metaphysis-common site for osteosarcoma Diachysis- common site for ewing's tumor Epiphysis- common site for osteoclastoma
Surgery
null
c5c32e97-ef5c-4b92-b4e8-1ff85c779318
All are common oral manifestations of HIV except?
Candidiasis
Aphthous ulcers
Hairy leukoplakia
Lichen planus
3d
multi
Ans. is 'd' i.e., Lichen planus Oral manifestations of HIV/AIDSFungal infectionsOral candidiasis (erythematous & pseudo membranous type)HistoplasmosisCryptococcosisViral diseasesHerpes simplexHerpes zosterHPV (warts)CMVHairy leukoplakia & HBVBacterial infectionsPeriodontal disease (linear gingival erythema, necrotizing...
Pathology
Infectious Disease
328a48e6-5247-4ec1-b679-8f2ac8fa7e2a
Which of the following is responsible for adhesion of platelets to the vessel wall?
Von Willebrand factor
Factor IX
Fibrinogen
Fibronectin
0a
multi
the Von-Willebrand factor is responsible for adhesion of platelets to the vessel wall. “Endothelial injury allows platelets to contact the underlying extracellular matrix; subsequent adhesion occurs through interactions with von Willebrand factor (VWF), which is a product of normal endothelial cells and an essential co...
Pathology
null
6a87b99d-dcb3-49ea-b985-abadac3b6cbf
Coracoid process is a ____________ kind of epiphysis -
Atavistic
Pressure
Traction
Aberrant
0a
single
null
Anatomy
null
9903c825-5f6d-47cb-88aa-393dec323c28
Long term side effect of glucocorticosteroids:
Hepatotoxicity
Osteoporosis
Precocious puberty
Lupus like syndrome
1b
single
Ans. B. OsteoporosisGlucocorticosteroid have many side effects like Cushing syndrome hyperglycemia, osteoporosis, delay in wound healing, increase in infection and many other.
Pharmacology
Endocrinology
c1a18b08-f746-45d8-80f4-41ede31adb67
Prussak's space is situated in:
Epitympanum
Mesotympanum
Hypotympanum
Ear canal
0a
single
(a) Epitympanum(Ref. Cummings, 6th ed., 1983)The space of the epitympanum, lying in between the Shrapnell's membrane or pars flaccida and the neck of malleus is known as "PRUSSAK'S SPACE".When the retraction pocket on Pars flaccida grows medially, it goes into this Prussak's space making this the most common site of pr...
ENT
Ear
d04f5d55-00e8-48f8-ba1a-b47baddf2e2c
Which is the purpose of adjusting the occlusion in dentures?
To obtain balanced occlusion.
To stabilize dentures.
To obtain even occlusal contacts.
All of the above.
3d
multi
Occlusal adjustment of dentures should be done with the premise of obtaining even occlusal contacts with balanced occlusion in order to stabilize the dentures during function.
Dental
null
efffccca-d3a5-4136-b26b-9f8e609d2b86
Which of the following enzymes is involved in the degradation of the basement membrane?
Metalloproteinases
Oxidases
Elastases
Hydroxylases
0a
multi
Matrix metalloproteinases are a family a proteolytic enzymes that degrade components of the extracellular matrix and basement membrane. Ref: Robbin's Basic Pathology 7th Edition, Page 110, 111, 312, 103; Clinical Gynecologic Endocrinology and Infeility By Marc A. Fritz, Leon Speroff, 2010, Page 596.
Biochemistry
null
0bd7db39-237c-4a87-a84a-68f113c5929b
In a case controlled study. It is found that the disease is more common in the group taking coffee as compared to the control group. The significance of this is -
Cause and effect relationship established
Disease median can be calculated
Caffeine is associated with occurrence of disease
Controls will not get the disease
2c
single
Ans. is 'c' i.e., Caffeine is associated with occurrence of disease Case-control study does not establish the cause and effect relationship because it can not distinguish between cause and associated factors. o Case-control study can only tell the association between cause and effect.
Social & Preventive Medicine
null
4dbf87c0-957a-491b-b3e0-372d785d0ef7
The commonest cyst to arise in pancreas after an attack of acute pancreatitis or pancreatic trauma is:March 2004
Serous cyst
Mucinous cyst
Pseudocyst
Malignant cyst
2c
single
Ans. C i.e. Pseudocyst
Surgery
null
89619730-6009-42db-97bb-2c42e2f10c5f
Which is the common amino acid between urea cycle and TCA?
Asparate
Alanine
Asparagine
Glutamate
0a
single
Ans. (a) AsparateRef: Satyanarayan Biochemistry, pg. 339Role of Aspartate in urea cycle:* Aspartate participates in urea cycle for condensation with citrulline to form Argino succinic acid. The reaction is catalyzed by Argino succinic acid synthetase (Asparate provides one out of the two nitrogens of urea, the other ni...
Biochemistry
Proteins and Amino Acids
0e0a80f9-42a2-4f0b-83da-effd52d8eb14
Which of the following structures is not at immediate risk of erosion by cholesteatoma ?
Long process of incus
Fallopian canal containing facial nerve
Horizontal/ lateral semicircular canal
Base plate of stapes
3d
multi
Ans. is 'd' i.e., Base plate of stapes Cholesteatoma has the propey to destroy the bone by viue of the enzymes released by it. Structures immediately at the risk of erosion are : - Long process of incus. Fallopian canal containing facial nerve. Horizontal / lateral semicircular canal
ENT
null
040babbf-80f2-4f25-8b92-062462c2229f
Third nerve palsy causes all except
Ptosis
Miosis
Outward eye movement
Diplopia
1b
multi
CN III palsy will cause diplopia not miosis.
Anatomy
null
367e4534-fef7-4ddb-aa13-ef2dc686a8a8
Substernal pain is a feature of:
Tachycardia
Emphysema
Angina pectoris
Thrombi and emboli
2c
single
null
Medicine
null
95472eb2-aece-47ba-a1f4-d9c6f9c7ee60
Normal splanchnic blood supply of the liver includes-
Portal vein
Splenic artery
Superior mesenteric artery
Inferior mesenteric vein
0a
single
Ans. is 'a' i.e., Portal vein * Liver has dual blood supply and receives 20% of its blood supply through hepatic artery (systemic) and 80% through portal vein (splanchnic). Portal vein is formed by union of splenic vein and superior mesenteric veins.* Venous drainage is through hepatic veins into IVC.
Anatomy
Abdomen & Pelvis
e092c51c-6d27-4406-ba01-f1b1c43468ad
In prolonged starvation the main energy source of brain is:
Glucose
Ketone bodies
Fructose
Fatty acids
1b
single
STARVE FEED CYCLE Divided into 5 stages: Well-fed state (1–4 hours after food) Early fasting (4–16 hours after food) Fasting (16–48 hours after food) Starvation (2–3 days without food) Prolonged starvation (> 5 days without food).
Biochemistry
null
8f99fcb8-8c5d-4639-94a9-34d09aecb646
Which of the following disorder is x-linked recessive ?
Gaucher disease
Neimann Kick disease
Tay Sachs disease
Fabry's disease
3d
single
Fabry's disease is x-linked recessive. Red are autosomal recessive.
Pediatrics
null
7bff6ca4-9b02-4ba9-9dae-08fb0d91c080
Zollinger Ellison syndrome is characterized by all of the following except -
Post bulbar ulcer
Recurrent duodenal ulcer
Severe diarrhoea
Massive HCL in response to histamine injection
3d
multi
null
Medicine
null
8d622bd1-e48d-43a7-9628-c3121335d777
National immunization programme, all are involved, EXCEPT:
TT
Hepatitis B
OPV
Measles
1b
multi
The vaccines recommended for National immunization programme are BCG, DPT, TT, OPV and measles. Hepatitis B is not recommended in National immunization programme. Ref: O.P. Ghai, 6Th Ed Page 200.
Pediatrics
null
552b8010-b294-44cf-b882-efc1d9d9011d
A 45-year-old woman has experienced worsening arthritis of her hands and feet for the past 15 years. On physical examination, there are marked deformities of the hands and feet, with ulnar deviation of the hands and swan-neck deformities of the fingers. Laboratory studies show an elevated level of rheumatoid factor. CB...
Autoantibodies against RBC membranes
Impaired synthesis of b-globin chains
Inadequate usage of stored iron
Sequestration of RBCs in splenic sinusoids
2c
single
The iron concentration and iron-binding capacity are low; however, in contrast to the finding in anemia of iron deficiency, the serum ferritin level is increased. This increase is typical of anemia of chronic disease. In this case, the chronic disease is rheumatoid arthritis. Underlying chronic inflammatory or neoplast...
Pathology
Blood
95e85ada-b61f-494d-8596-7a12cea5d31b
True about femoral hernia is -
Occurs exclusively in females
Pregnancy is common cause
Doesn't strangulate
In males associated with cryptorchidism
1b
multi
Answer is 'b' i.e. Pregnancy is common cause Femoral hernia In this hernia the abdominal contents pass through the femoral ring, traverse the femoral canal and come out through the saphenous opening. It is more common in females (But remember that most common hernia in the females is not femoral, but it is indirect ing...
Surgery
null
b0343895-cf99-47fd-b6eb-bc34ed101ca0
Most common association with Acanthosis nigricans ?
Hypeension
DM
Obesity
Hypothyroidism
2c
single
Ans. is 'c' i.e., Obesity Acanthosis nigricans is a brown to black, velvety hyperpigmentation of the skin. It is usually found in body folds, such as posterior & lateral folds of neck, axilla, groin, umblicus, forehead. It typically occurs in individuals younger than 40 years of age. Histopathologically papillomatosis ...
Skin
null
1aa63afc-f782-4ea1-af9e-d7e32ef24789
Delirium is seen in which of the following poisonings
Dhatura
Lead
Opioid
All
3d
multi
A i.e. Dhatura; B i.e. Lead; C i.e. Opioid - The Deliriant poisons are - 'Hy - AB - CD' i.e. Hyoscyamus, Atropa Belladona, Cannabis, DhaturaQ - Opium & chronic Lead poisoningQ also causes delirium
Forensic Medicine
null
287bd3e6-0982-46f8-b205-63d8721e1e82
A 74-year-old woman has noted increasing size and number of darker brown patches on the dorsum of each hand for the past 15 years. They do not change with sun exposure, are nonpruritic, and non-tender. On examination, these 0.5- to 1-cm lightly pigmented lesions are flat. Which of the following is the most likely micro...
Basal melanocytic hyperplasia
Dermal nevus cells
Loss of melanin in surrounding skin
Mast cell proliferation
0a
single
Unlike a freckle that darkens upon light exposure, lentigo (pleural:lentigenes) does not. There is a focal increase in melanocytes of the basal layer, along with thinning of epidermis and elongation of rete ridges. Lentigines can occur at any age; those in older persons may be termed senile lentigines or age spots. A n...
Pathology
Skin
cc31a3a5-a1be-4a72-addb-1ccdf0ae555f
Pericardial space is present between
Parietal and visceral pericardium
Endocardium and pericardium
Epicardium and pericardium
Endocardium and epicardium
0a
single
Pericardial space (pericardial cavity) lies between parietal serous pericardium and visceral serous pericardium.
Anatomy
null
9131f053-9731-4eed-a834-59ec4f4c4d15
Danazol is used in all except :
Hirsutism
Endometriosis
Dysfunctional uterine bleeding
Fibroid
0a
multi
null
Gynaecology & Obstetrics
null
0fe98237-9348-4c3b-a554-e0187760c9f4
Which is NOT a feature of polymyositis?
Pharyngeal muscle involvement
Gottron's rash
Proximal muscle involvement
Pain in limbs
1b
single
Answer is B (Gottron's rash) : Gottron's rash is a feature of dermatomyositis and is characterized by erythema of knuckles witlz raised violaceous scaly eruptions. No rash is seen in patients of polymnyositis Polymyositis is essentially a diagnosis of exclusion Polymyositis is a subacute inflammatory myopathy affecting...
Medicine
null
e5c9f88f-3af3-42ca-a6c7-f4a995a7caf0
Transmission of R factor is by -
Conjugation
Transduction
Transformation
Lysogenic conversion
0a
single
Conjugation Bacterial conjugation is the transfer of genetic material between bacteria through direct cell to cell contact or through a bridge- like the connection between two cells. Conjugation is a process whereby a donor (male) bacterium makes physical contact with a recipient (female) bacterium. Donor status is de...
Microbiology
null
0c3210af-dd70-47ff-910c-5043b1c363ff
Boutonniere deformity involves:
Flexion at PIP and DIP joint
Extention at PIP and DIP joint
Flexion at PIP and extention at DIP joint
Extention at PIP and flexion at DIP joint
2c
single
Boutonniere deformity involves: Flexion at PIP and extention at DIP joint seen in RA Other deformities in RA- Swan-neck deformity Z-deformity of thumb Ulnar detion of fingers
Orthopaedics
Joint Disorders
29524a4b-6be9-4a26-812c-5d9396424156
Infective stage for mosquito in case of Plasmodium vivax is:
Gametocyte
Sporozites
Tropozoites
Merozoites
0a
single
Gametocyte
Microbiology
null
4123625b-2917-492a-b800-b094adbc76b0
Rhinitiss sicca involves
Anterior nares
Septum
Posterior wall
Lateral wall
1b
multi
Rhinitis sicca is a crust-forming disease seen in patients who work in hot, dry and dusty surroundings, e.g. bakers, iron- and goldsmiths.Condition is confined to the anterior third of nose paicularly of the nasal septum. Here, the ciliated columnar epithelium undergoes squamous metaplasia with atrophy of seromucinous ...
ENT
Nose and paranasal sinuses
ec178a6c-85a6-4779-bc02-2177efacf99f
Most abundant and common complement component for both the pathways is:
C3
C5
Clq
C8
0a
multi
C3
Pathology
null
da715cdc-7b0e-4af0-81f1-07c6f44ef243
Cat is an agent for transmission of the following disease of man -
Isospora hominis
Fasciola hepatica
Toxoplasma gondii
Chilomastrix mensili
2c
single
Cat and other felines- definitive host Human - intermediate host (Refer pgno:64 baveja 3 rd edition)
Microbiology
parasitology
453400f4-8772-45e6-9e35-63e9e32f11f1
Screening of neonatal thyroid disease is done by
T4
T3
TSH
TPO antibodies
2c
single
Since the neonates are asymptomatic at bih all newborns are screened for neonatal hypothyroidism. TSH is estimated either in cord blood at the time of bih (preferred) or blood obtained from heel prick after 2 days of bih.(Refer: Nelson's Textbook of Pediatrics, SAE, 1st edition, pg no. 2669 - 2773)
Pediatrics
All India exam
24a5809c-da4e-4589-a1a5-dfec6afcd20d
The roof of the olfactory region is formed by ?
Nasal bone
Cribriform plate of ethmoid
Sphenoid
Temporal bone
1b
single
Ans. is 'b' i.e., Cribriform plate of ethmoid The olfactory mucosa lines the upper one-third of nasal cavity including the roof formed by cribriform plate and the medial and lateral walls up to the level of superior concha (turbinate).
Anatomy
null
6b1609d4-0745-43d3-8210-e222eb697867
The most appropriate circuit for ventilating a spontaneously breathing infant -
Jackson Rees modification of Ayre's T piece
Mapleson A or Magill's circuit
Mapleson C or water's to & fro canister
Bain's circuit
0a
single
Ayre&;s T piece is used in infants. The patient inspires fresh gas from the reservoir tube,expires into the reservoir tube. Advantages are they are inexpensive,compact,no valves and low dead space
Anaesthesia
Anaesthetic equipments
dc084aa0-bb3a-4408-ab4f-d3005b48cde6
Investigation of choice in postcoital bleeding in a 60 years old lady is :
Pap smear
Colposcopy and biopsy
Pelvic ultrasound
Cone excision of cervix
1b
single
Ans. is b i.e. Colposcopy and biopsy investigation of choice in post-coital bleeding in a 60 years old lady (which suggests carcinoma cervix) is Colposcopy and Biopsy. The aim of Colposcopy is : - to confirm the diagnosis - to identify the extent of lesion - it allows conservative treatment in case of precancerous lesi...
Gynaecology & Obstetrics
null
16ad6c75-c769-41ad-85f2-bc3b4cec9a39
Primary pleural tumor is ?
Mesothelioma
Myxoma
Lipoma
Fibroma
0a
single
Ans. is 'a' i.e., Mesothelioma & 'd' i.e., Fibroma The pleura may be involved by primary or secondary tumors. Primary tumors Benign - Solitary fibrous tumor (benign fibrous mesothelioma or benign mesothelioma or pleural fibroma). Malignant - Malignant mesothelioma. Secondary tumors More common than primary tumors. Most...
Pathology
null
41ff3cbd-e0a1-47cc-ac7a-f1cca5fdef54
Epalrestat is a
Antihypeensive drug
Antidiabetic drug
Anti tubercular drug
None of the above
3d
multi
Epalrestat is analdose reductase inhibitor. There by it reduces the formation of sorbitol from glucose. Sorbitol acts like a tissue toxin. "Long-term treatment with epalrestat is well tolerated and can effectively delay the progression of diabetic neuropathy and ameliorate the associated symptoms of the disease, paicul...
Anatomy
All India exam
93fbd343-6ce9-4778-8c1f-3aaa87078ada
Mechanism of action of cholera toxin is
Ganglioside
Adenyl cyclase
Both 1 and 2
Exotoxin
2c
multi
CHOLERA ENTEROTOXIN Light (L) toxin : Binds with ganglioside in epithelial cell membrane Heavy(H) toxin : Activates Adenyl cyclase in Epithelial cell wall which increase camp, leading to outpouring of isotonic fluid in lumen of intestine Ref: Park 25th edition Pgno : 253
Social & Preventive Medicine
Communicable diseases
fc9a4e65-d6d3-454b-8fd8-eb8fa49cd5b0
Tissue elevation of which of the following cause vasoconstriction :
Na+
K+
Mg
Ca2+
3d
single
Ans. D. Ca2+Vascular Control by lons and Other Chemical Factors Guyton 12th(SAE)/269An increase in calcium ion concentration causes vasoconstriction.An increase in potassium ion concentration,.within the physiological range, causes vasodilation.An increase in magnesium ion concentration causes powerful vasodilation.An ...
Physiology
null
a051b259-e4df-450a-a9d8-804432ba0176
Vital statistics in a population include:-
Sex ratio
Age composition
Bih rate
Dependency ratio
2c
single
Population statistics Vital statistics Population size Sex ratio Density of population Dependency ratio Bih rate, death rate Natural growth rate Life expectancy at bih Moality rates Feility rates
Social & Preventive Medicine
Definition & Concepts
6ab6f443-ebe0-4dd5-9e7d-e4266a376fd9
A 26yr old pregnant mother who had previous twin delivery visits ANC OPD for routine check up she is sure of her dates with 36 wks pay what is the obstetric score
g3p1
g2p1
G2P2
G3P2
1b
single
REF : DUTTA 9TH ED
Gynaecology & Obstetrics
All India exam
1753717c-e558-473b-88aa-adb878c40fdf
Wrong statement is –
Mees line in arsenic poisoning
Pterygium of nails in Lichen planus
Onycholysis in Psoriasis
Koilonychia in Megaloblastic Anemia (B12 def)
3d
multi
Koilonychia is seen in iron deficiency anemia (not in megaloblastic anemia). Mees line is seen in Arsenic poisoning. Pterygium is diagnostic for lichen planus. Psoriasis can cause onycholysis
Dental
null
94741fb9-e52a-42c1-8df5-59f338e300b9
The MOST appropriate time for self-examination of breast in relation to menstraution in a pre-menopausal woman is?
A week after menstruation stas
Before ovulation
During menstruation
A day after menstruation ends
0a
single
Breast self-examination is to be performed by all women above 18 years throughout their life. It should be performed every month at the same time of menstrual cycle. For pre-menopausal women: The best time is right after the menstrual cycle ends (7-10 day; after menstrual cycle stas) as at this time the breasts are les...
Gynaecology & Obstetrics
null
9d454253-7fa4-4401-8f5c-2f019adf5101
True about anatomy of right ventricle
Situated posteriorly
More prominent trabeculation
Crista supraventricularis separate tricuspid valve & pulmonary valve
Ellipsoidal in shape
1b
multi
Forms the major poion of the anterior surface of the hea Right ventricle is divided into 2 pas: an inflow poion named "the sinus" and an outflow poion named "the conus" separated by the crista supraventricularis. As opposed to the normal left ventricle, the right ventricle is highly trabeculated the right ventricle is ...
Anatomy
Thorax
a110dad9-ff70-4a1e-a727-7a94cfa2057d
Ratio of sulfamethoxazole and trimethoprim in cotrimoxazole tablet is:-
5:01
1:05
1:01
5:05
0a
single
COTRIMOXAZOLE This is a fixed dose combination of sulfamethoxazole and trimethoprim in a ratio of 5:1. Due to different bioavailability (more for sulfamethoxazole), plasma concentration of the two drugs attained is 20:1 (in vivo), which is the best bactericidal concentration required. The bactericidal activity is due t...
Pharmacology
Antimetabolites and Quinolones
f3685985-6ba5-4545-b999-611bb3cf5a20
Subacute bacterial endocarditis is caused by
Streptococcus viridans
Haemolytic streptococci
Staphylococcus aureus
Nisseria
0a
single
null
Microbiology
null
d73557d4-5a1a-4f36-af3a-185d8971e239
Which is an example of disability limitation
Resting the affected limb in neutral position
Arranging for schooling of a child suffering from PPRP
Reducing occurrence by polio immunisation
Providing calipers for walking
0a
single
Disability: Any restriction or lack of ability to perform an activity in the manner or within the range considered normal for human being. Disability Limitation: It is mode of intervention when patient repos late in the pathogenesis phase. The objective of this intervention is to prevent or halt the transition at' the ...
Surgery
null
d8116110-88bf-45c6-b43f-4e22e80b614c
The function of minor connector is
Connects major connector to all components of the RPD
Prevents gingival displacement of the RPD
Allows a single path of placement of the RPD
It is that unit of RPD to which all other parts are directly or indirectly attached
0a
multi
null
Dental
null
b07944cc-4026-4799-926b-e15e120ef6ba
Type B gastritis is
Body predominant
H. pylori associated
Autoimmune gastritis
Environmental gastritis
1b
single
Type B gastritis mainly involves the region of antral mucosa (hence antral predominant not body predominant.) and is more common. It is also called hypersecretory gastritis due to excessive secretion of acid, commonly due to infection with H. pylori. These patients may have associated peptic ulcer. Unlike Type A gastri...
Pathology
G.I.T
aa317892-de0d-46ec-9d03-e3c08fbee204
An ABG analysis shows : pH 7.2, raised pCO2, decreased HCO3; diagnosis is :
Respiratory acidosis
Compensated metabolic acidosis
Respiratory and metabolic acidosis
Respiratory alkalosis
2c
single
Answer is C (Respiratory and metabolic acidosis) The acid base disorder is therefore both respiratory and metabolic acidosis. There is acidosis (pH < 7.35). Raised PCO2 (acidosis) indicates that change in CO2 is in keeping with change in pH. The respiratory component is therefore primary. Decreased HCO3 (acidosis) indi...
Medicine
null
979f9d80-273e-49a4-95ee-5bb170c6200f
Storage temperature for vaccine is: A
--4degC to 0degC
0degC to 4degC
+2degC to 8degC
+4degC to 12degC
2c
single
+2degC to 8degC
Social & Preventive Medicine
null
c563d00a-06f9-4c5c-976b-b90077480d77
Retinoblastoma gene is located on chromosome -
6
9
13
21
2c
single
Harshmohan textbook of pathology 7th edition RB gene is located on long arm chromosome 13. This is the first ever tumor suppressor gene identified and this has been amply studied..
Pathology
General pathology
84845059-672d-4f44-9691-e62e8812927e
All are associated with AIDS EXCEPT:
Increased p 24 Ab
Hypogammaglobulinemia
Abnormal mitogen assay
Anergy
1b
multi
ANSWER: (B) HypogammaglobulinemiaREF: Harrisons 18th ed chapter 189Even though HIV causes immune suppression, it causes hypergammaglobulinemia rather than hypogammglobulinemiaIncreased p24 antibody: basis for detection in window period.T cell anergy is commonly seen in HIVAbnormal response of T cells to mitogens is a t...
Medicine
Virology
17819a61-a4f2-4f92-93a0-a6de01eb8193
Hand deformity presennting as hyper-extension at the metcarpo phalaogeal joint and flexion at inter-phalanngeal joint, occurs due to paralysed
Flexor digitorum profundus
Lumbricals
Lumbricals and interossei
Extensor digitorum
2c
single
Interossei and lumbricalsflexes MCP (metacarpophallangeal joint) and extend IP (interphallangeal joint). Injury to interossei and lumbricals leads toclaw hand (extended MCP and flexed IP)
Anatomy
NEET Jan 2020
97c1e5e7-6935-4bb3-adef-7d62f28690fe
Essential pentosuria is due to defect in
HMP pathway
Glycolysis
Gluconeogenesis
Uronic acid pathway
3d
single
It is an inborn error of metabolism.In the pathway, L-xylulose is conveed to D-xylulose by two enzymes, xylitol dehydrogenase, and xylulose reductase.Absence of any of these enzymes leads to pentosuria.Ref: DM Vasudevan, 7th edition, page no: 135
Biochemistry
Metabolism of carbohydrate
565c7f96-85ea-4522-8986-8b04a9b44bc4
Anti retro viral drug causing urinary stones:
Zidovudine
Lamivudine
Indinavir
Nelfinavir
2c
single
Ans: c (Indinavir) Ref: Harrison, 16th ed, p. 1127; 17th ed, p. 1192Indinavir is the antiretroviral drug which causes urinary stones.Classification of antiretro viral drugNucleoside reverse transcriptase inhibitors (NRTI)* Zalcitabine* Didanosine* Lamivudine* Zidovudine* Stavudine* Abacavir* EmtricitabineProtease inhib...
Medicine
Infection
b94c16a4-597d-4291-90cf-a14976a5ac45
Poor prognostic factor of non Hodgkin's lymphoma is -
Age > 60 years
Weight loss > 10%
Night sweats with loss of weight
All of the above
3d
multi
null
Medicine
null
c00f2006-5004-42dc-ae53-90de0cd71b02
Lutembacher syndrome includes all the following except
Mitral stenosis
ASD
VSD
Left to right shunt
2c
multi
Lutembacher syndrome is defined as a combination of mitral stenosis and a left-to-right shunt at the atrial levelTypically, the left-to-right shunt is an atrial septal defect (ASD) of the ostium secundum varietyBoth these defects, ASD, and mitral stenosis can be either congenital or acquired.(Refer: OP Ghai's Textbook ...
Pediatrics
All India exam