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135
858b735d-393c-43e5-afff-21708d5ab677
Which of the following is a manifestation of 22q11 mutation syndrome?
Hypercalcemia
Conotruncal abnormalities
Thymic hyperplasia
Dysmorphogenesis of the 1st and 2nd pharyngeal pouches
1b
single
Chromosome 22q11.2 deletion syndrome encompasses a spectrum of disorders that result from a small deletion of band q11.2 on the long arm of chromosome 22. It is also called as Velocardiofacial syndrome or DiGeorge syndrome It is characterized by Dysmorphogenesis of the 3rd and 4th pharyngeal pouches resulting in follow...
Pathology
JIPMER 2017
aaab69a3-1021-4981-947f-7ab4ddeb233e
All of the following are true about medulloblastoma except?
It is the most common primary malignant brain tumor in childhood
Isochrome 17q indicates poor prognosis
Most common site is brainstem (medulla)
Tumor is highly radio sensitive
2c
multi
Medulloblastoma occurs exclusively in the cerebellum.
Pathology
null
071f1b94-3e92-4da4-bd9c-a12bf8a4138f
A 40-year-old man complains of nausea, vomiting, diarrhea, and cramping abdominal pain. His temperature is 38degC , blood pressure 90/60 mm Hg, and pulse rate 90/minute. On physical examination, the patient appears dehydrated, with sunken eyeballs, dry tongue, and poor skin turgor. Hyperpigmentation is noted in the pal...
Amyloidosis
Autoimmunity
Metastatic cancer
Sarcoidosis
1b
multi
- Given clinical features suggests the diagnosis of Primary chronic adrenal insufficiency (Addison disease). - MCC of addison disease in developed countries - Autoimmunity - MCC of addison disease in developing countries like India - Tuberculosis - It is fatal wasting disorder caused by failure of adrenal glands to pro...
Pathology
Adrenal Gland
4633f9a7-b324-4db0-a18d-22abca324997
Internucleosomal cleavage of DNA is characteristic of:
Reversible cell injury
Irreversible cell injury
Necrosis
Apoptosis
3d
single
. Apoptosis
Pathology
null
a26c3a77-a853-41dc-a22e-3c5042caa70f
An 8-year-old child has had abdominal pain and dark urine for 10 days. Physical examination shows blotchy purple skin lesions on the trunk and extremities. Urinalysis shows hematuria and proteinuria. Serologic test results are negative for MPO-ANCA (P-ANCA) and PR3-ANCA (C-ANCA). A skin biopsy specimen shows necrotizin...
Giant cell arteritis
Henoch-Schonlein purpura
Polyarteritis nodosa
Takayasu arteritis
1b
multi
In children, Henoch-Schonlein purpura is the multisystemic counterpart of the IgA nephropathy seen in adults. The immune complexes formed with IgA produce the vasculitis that affects mainly arterioles, capillaries, and venules in the skin, gastrointestinal tract, and kidney. In older adults, giant cell arteritis is see...
Pathology
Blood Vessels
6865f332-6232-457b-9d77-f9ecacb27436
A 55-year-old woman presents to the clinic for evaluation of several weeks of fever, abdominal pain, weight loss, and lack of energy. Three days prior to the assessment, she developed a left foot drop. Her blood pressure is 160/90 mm Hg, pulse 80/min, and the physical examination confirms left peroneal nerve damage and...
nephrotic syndrome
diffuse glomerulonephritis
granuloma formation
necrotizing vasculitis of vessels
3d
multi
This patient has polyarteritis nodosa (PAN) and in classic PAN, unlike microscopic polyangiitis, both small and medium vessels are involved. The renal lesions are ischemic secondary to fibrinoid necrosis of the vessels. In microscopic polyangiitis, a diffuse glomerulonephritis is frequently present. The most common org...
Medicine
Immunology and Rheumatology
35ca550a-45f2-4a61-9dce-50be0a4fddaa
Most common type of renal stone is: March 2013 (d)
Calcium phosphate
Magnesium ammonium phosphate
Cystine
Uric acid
0a
single
Ans. A i.e. Calcium Phosphate
Surgery
null
1377975f-82b5-4d88-b412-2bf071ab6557
A 14 year old female patient complains of decayed teeth. Intra-oral examination reveals restoration of occlusal caries with composite restoration. Which of the following lasers is used for curing of this restorative material?
Argon
CO2
Nd:YAG
Excimers
0a
single
null
Dental
null
7362fd06-c3df-46d4-a540-a965d94044f9
Drug of choice in amoebic liver abscess is
Metronidazole
Ciprofloxacin
Emetine
Chloroquine
0a
single
(A) Metronidazole # Metronidazole acts directly on the trophozoites of E. histolytica. Because of high concentration in liver extensively small amounts of drug (800 mg, TDS X 5-10 days) effective in Amoebic Liver Abscess.
Medicine
Miscellaneous
7c89c715-6550-4e2f-b9b2-850b4cd18593
WHO immunization evaluation coverage survey is normally done in what age group?
0-12 months
6-12 months
12-23 months
9-12 months
2c
multi
Ans. is 'c' i.e., 12-23 months WHO used 30 x 7 technique (total = 210 children) for cluster sampling in which there are 30 clusters, each containing 7 childrenwho are 12 - 23 months old and are completely immunized for primary immunization (till measles vaccine at 9 month).
Social & Preventive Medicine
null
df3970b5-3069-468f-8f62-1998c296b1fd
Pseudokidney sign' on USG is seen in
Trichobezoar
CA stomach
CA kidney
Polycystic kidney
1b
single
Ans. CA stomach
Radiology
null
96ab155c-44b2-4954-9f83-46351c695ae5
Robe Koch assistant advised him to use agar instead of gelatin for solidifying culture media for cultivation of bacteria because
Agar has more nutrients
Gelatin melts at 37oC
Gelatin is not easily available
Agar is cheaper
1b
single
Gelatin was the substance originally used to gel culture media. However, gelatin is liquid at 35oC., the optimum temperature for many bacteria. In addition, some bacteria are capable of liquifying the gelatin, making it an unsuitable solidifying agent. Agar has neither of these drawbacks. Agar is preferred over gelatin...
Microbiology
General Microbiology Pa 1 (History, Microscopy, Stains and Structure and Physiology of Bacteria)
fdf227d8-28d6-4227-9b28-64603b7ede70
Super imposition technique is used in :
Skull
Pelvis
Femur
Ribs
0a
single
A i.e. Skull
Forensic Medicine
null
745ba1fd-2544-40a6-b63d-a566e7ae55a8
True about citrate in ORS
Cheaper
Nutritious
Increases shelf
Tastier
2c
multi
In WHO ORS, sodium bicarbonate has been replaced by trisodium citrate: – Makes the product more stable – Results in less stool output (especially in high-output diarrhoea like cholera) as it increases intestinalabsorption of sodium and water
Social & Preventive Medicine
null
96f7f42d-8ace-46f8-a2dd-025c23806164
All the drugs given below can be used to protect gastric ulcer except
Colloidal bismuth salt
Magnesium hydroxide
Misoprostal
Sucralfate
1b
multi
null
Pharmacology
null
a381488f-e5af-4b6b-806d-e79746c26755
Isolation period should be -
Minimum incubation period
Maximum incubation period
Period interval
Generation time
2c
single
Isolation is defined as the period of communicability of infected person or animals from others in such places and such strict conditions as to prevent or limit the indirect transmission of the infectious agent from those infected to those who are susceptible or who may spread the agent to others (refer pgno:120 park 2...
Social & Preventive Medicine
Epidemiology
b1c66b28-2e67-4493-8e69-4e688d2dbc28
Dangerous area of eye:
Ciliary body
Optic nerve
Sclera
Choroid
0a
single
A i.e. Ciliary body
Ophthalmology
null
a58706d7-15ec-4967-9531-fcce6589b277
Hummingbird sign in brain MRI is seen in ?
Multiple sclerosis
Progressive supranuclear palsy
Parkinson's disease
Alzheimer disease
1b
single
Ans. is 'b' i.e., Progressive supranuclear palsyHummingbird sign on brain MRI is a radiological sign of progressive supranuclear palsy.
Radiology
null
48465792-936f-4fe6-bac6-bb438f625113
The commonest site of lytic lesion in multiple myeloma is -
Vertebral column
Femur
Clavicle
Pelvis
0a
single
null
Pathology
null
27532934-1b14-4e2b-8c9c-f3077c86934e
Earliest radiological change in RHEUMATOID AHRITIS is ?
Decreased joint space
Aicular erosion
Periaicular osteopenia
Subchondral cyst
2c
single
REF : MAHESWARI 9TH ED
Orthopaedics
Joint disorders
8350460d-b64e-4d21-985f-a41e259d17a7
Hypopigmented patches are seen in
Nevus ota
Nevus Ito
Nevus anemicus
Becker nevus
2c
single
Nevus anemicus presents as a single or multiple patches of hypopigmentation with ill-defined margins merging into normal skin present at bih or thereafter. Nevus anemicus presents as congenital hypopigmented patches with a well-defined border. They are asymptomatic and typically seen on the upper trunk, although they h...
Dental
Autoimmune skin disorders
70adf425-091e-4a76-86b5-6b040fdf5e72
A premature infant is more likely than a full-term infant to –
Suffer from jaundice of hepatic origin
Maintain in normal body temperature in a cold environment
Excrete urine with a uniform specific gravity
Suffer from anaemia
0a
single
The liver of premature (preterm) neonate is functionally immature that leads to hypoglycemia, hyperbilirubinemia (jaundice) and poor detoxification of drugs. Problems of preterm Premature babies Birth asphyxia                                            Hypothermia                                                      ...
Pediatrics
null
db89b77b-f178-4898-835b-f75c49a81ad1
Least post translational modification occurs in
t-RNA
Prokaryotic r- RNA
Eukaryotic r - RNA
Prokaryotic mRNA
3d
single
D i.e. Prokaryotic mRNA
Biochemistry
null
63f7212b-1ea6-463e-8107-7d33db8989f9
In myasthenia gravis, antibodies are present against:September 2012
Muscarinic receptor proteins
Nicotinic receptor proteins
Protein actin
Protein myosin
1b
single
Ans. B i.e. Nicotinic receptor proteinsMyasthenia gravisIt is an autoimmune neuromuscular disease leading to fluctuating muscle weakness and fatigability.It is an autoimmune disorder, in which weakness is caused by circulating antibodies that block acetylcholine receptors at the postsynaptic neuromuscular junction, inh...
Pathology
null
3191c068-3f1d-4f0e-a044-a395faa2501d
Mineral oils are used in mosquito control measure as -
A personal protection method
Larvicide
Adulticide
Space spray
1b
single
Mineral oils are used as chemical control against mosquito larvae. The mineral oil application to water is the oldest method to control mosquito. oils used are diesel oil, fuel oil, kerosene oil, and crude oils. Special mosquito larvicidal oils are also available. Oil kills larvae and pupae within a sho time after appl...
Social & Preventive Medicine
Environment and health
b8cd6e73-ffe3-4e2e-9278-ae04370bb5b7
A patient with congenital nephrotic syndrome requires which of the following procedures?
Live attenuated vaccines
Renal biopsy
Steroids in high doses
Low protein diet
1b
single
Congenital nephrotic syndrome is a very rare form of nephrotic syndrome. It occurs predominantly in families of Finnish origin and manifests sholy after bih. It is an inherited disorder. The condition is caused by a defect in the protein nephrin. Requires renal biopsy for diagnosis.
Pediatrics
null
64cdc85e-b189-4321-a2b5-0a4345774be0
A woman presents with a thick curdy -- white vaginal discharge. The best treatment for her is :
Miconazole
Metronidazole
Nystatin
Doxycyclin
0a
single
Miconazole
Gynaecology & Obstetrics
null
13b01f2b-571f-4d7c-b120-c35f64f1d647
Iodised salt is given in an area endemic to Goiter. Type of prevention:
Health promotion
Specific protection
Primordial prevention
Treatment
1b
single
Ans. (b) Specific protectionRef : K. Park 23rd ed. / 41, 370-73* Iodised salt is given in an area which has risk of developing goiter. This is a primary level of prevention done by specific protection.* Primordial prevention is done before the emergence of risk factor.
Social & Preventive Medicine
Concept of Health and Disease
b4a39fc4-b39d-455a-8ff3-960a2426667e
Consider the following statements; giant cells are a characteristic histopathologic finding in
Apthous ulcers
Keratocyst
Brown tumor of hyper parathyroidism
Dentigerous cyst
2c
multi
null
Pathology
null
8d31e36f-58fe-443a-b1c7-db49c70911ac
Modified Ziehl-neelsen staining is used for:
Mycobacterium tuberculosis
Mycobacterium bovis
Nocardia
All of the above
3d
multi
Ans. is. 'd' i. e., All of the above
Microbiology
null
5184ba3a-2c28-4c94-a11d-9548ae8b822d
Type of Collagen in Hyaline Cartilage is
Type I
Type II
Type III
Type IV
1b
single
Types of Collagen in different tissues Type I - Bone, skin Type II - Hyaline and elastic Cartilage Type III - Skin, ligament, blood vessels Type IV - Basement membrane in various tissue Type V - Blood vessel wall, Synovium, corneal stroma
Anatomy
null
add97165-2e8e-40c7-81e0-471cadf7e98b
Flaying is seen in which type of laceration -
Tear
Avulsion
Split
Stretch
1b
single
The synopsis of forensic medicine & toxicology ; Dr k.s.narayan reddy ;28th edition ; Pg.no. 110 & 111 . Flaying comes under avulsion .The shearing & grinding force by a weight ,such as lorry wheel passing over a limb ,may produce seperation of skin from underlying tissue (avulsion ) over a relatively large area .This ...
Forensic Medicine
Mechanical injuries
a9d2839a-731a-4614-aaf6-c93affc1cb04
Site of action of vecuronium is -
Cerebrum
Reticular formation
Motor neurone
Myoneural junction
3d
single
Ans. is 'd' i.e., Myoneural junction Vecuronium is a nondepolarizing (competitive) neuromuscular blocker. The site of action is the end plate of skeletal muscles (End plate is thickened poion of muscle membrane at neuromuscular junction).
Pharmacology
null
e1c8b93e-01e8-4b5e-aec5-e8d357eec645
FALSE about Leprosy eradication programme is ?
Early detection of cases
Disability limitation
Long term multi drug therapy
Health education
2c
multi
Ans. is 'c' i.e., Long term multidrug therapy o In leprosy eradication programme the multidrug therapy is not long term but sho term therapy. o Shoer therapy has added advantage of patient compliance, cost-effectiveness and decreased work load.
Social & Preventive Medicine
null
342d31de-583c-4769-80a5-9f323e690d0c
The intermediate syndrome in organophosphorus poisoning refers to the occurence of which of the following?
Cholinergic syndrome with hypersecretion
Organophosphate induced polyneuropathy
Organophosphate induced delayed neuropathy
Motor cranial nerve palsies
1b
single
Intermediate Syndrome: This has been repoed in some patients and is characterized by weakness of the upper extremities and neck musculature, cranial nerve palsies and secondary respiratory arrest. It may occur between 24 and 96 hours after ingestion.Delayed Neuropathy: May sometimes occur 1-4 weeks after exposure. The ...
Forensic Medicine
Special topics
988f4632-4816-4ae5-8048-ae2f3b4e40f9
The main pathway for "De - Novo" synthesis of fatty acids occurs in
Mitochondria
Nucleus
Cytosol
None of the above
2c
multi
null
Biochemistry
null
49a2ffaf-a152-4a0d-8df3-e31c3403555b
Primary lesion in lichen planus is:
Macule
Papule
Vesicle
Bulk
1b
single
null
Pathology
null
f66a9478-28b0-4564-8694-90ea49833677
Which of the following inhalational agents has the maximum blood gas solubility coefficient?
Isoflurane
Sevoflurane
Desflurane
Nitrous oxide
0a
single
Blood-gas paition coefficient, also known as Ostwald coefficient for blood-gas, is a term used in pharmacology to describe the solubility of inhaled general anesthetics in blood. The coefficient is defined as the ratio of the concentration in blood to the concentration in gas that is in contact with that blood when the...
Anaesthesia
General anaesthesia
294dbdff-0d70-427d-a19b-2d40307c5611
Blood form of folic acid is -
Folinic acid
Pteroglutamate
Methyl THE
None
2c
multi
Ans. is 'c' i.e., Methyl THE Folic acid is absorbed in the jejunum. Following absorption, folic acid is transpoed in blood by two (3-globulins. The major circulating form is methyltetrahydrofolate and the normal concentration range is 5-15 ng/ml. Once it arrives in the liver, the methyl derivates are taken up by hepato...
Biochemistry
null
e5715690-ed6e-4f36-9e39-f7a06e116133
Changes in the gingiva during pregnancy are attributed to
Changes in the hormonal level
Altered microorganisms
Altered immunological responses level
All the above
0a
multi
null
Dental
null
59f6ea2f-1099-44c2-8502-c9a9a8b5f202
A female comes with normal breast development but scanty pubic hair. What is the most likely diagnosis ?
Turner's syndrome
Testicular feminizing syndrome
Mullerian agenesis
Gonadal dysgenesis
1b
single
Androgen insensitivity syndrome (AIS), formerly known as testicular feminization, is an X-linked recessive condition resulting in a failure of normal masculinization of the external genitalia in chromosomally male individuals. Adolescent patients have no pubic and axillary hair, with otherwise scanty body hair, and lac...
Gynaecology & Obstetrics
null
9f160a97-e9ec-4e15-b1bf-d5df088e7c59
A patient came with dyspnea, elevated JVP and edema in the feet. Lungs are clear. There is a parasternal heave and S2 is palpable in the pulmonary area. Which one of the following is LEAST helpful in determining etiology?
Echo for mitral stenosis
Anti-endomysial antibody estimation
ELISA for HIV
Urine/stool examination for Schistosoma ova
1b
single
* The findings of dyspnea, elevated JVP and pedal oedema are suggestive of right sided CHF * Parasternal heave and palpable S2 indicates pulmonary aery hypeension * This also explains why lungs are clear since pulmonary oedema is absent in PAH * Reduced RV compliance in RVH leads to elevated JVP and oedema in feet * Th...
Medicine
Hypeension
145a9614-2362-4e17-8246-c927fdbbd6a7
Which of the following clotting factors helps in bridging the fibrin in a clot and stabilizes the clot?
Factor III
Factor V
Factor VIII
Factor XIII
3d
single
Factor XIII is also called as fibrin stabilizing factor. It is activated by thrombin. Activated factor XIII strengthens the fibrin reticulum. The fibrin monomer molecules are initially held together by weak non covalent hydrogen bonding, and the newly formed fibers are not cross linked with each other. Therefore as a r...
Physiology
null
ba369469-747c-4009-aa72-25f1ca6cba6e
Mature defence mechanism is-
Sublimation
Denial
Projection
Distortion
0a
single
Ans. is 'a' i.e., Sublimation Defence mechanismo Narcissistic (Psychotic) :- Denial, disortion, projection.o Immature :- Blocking, introjection, passive-aggressive behavior, acting out, hypochondriasis, regression, schizoid fantasy, somatization.o Neurotic :- Controlling, Displacement, inhibition, extemalization, intel...
Psychiatry
Cognitive Development
7115e8cb-52ba-422d-897e-8f0c97913efd
Best screening test for pheochromocytoma?
Urinary VMA estimation
Serum catecholamine estimation
Clonidine suppression test
Urinarymetanephrine
0a
single
Ans: a (Urinary VMA estimation)Ref: Vasudevan & Sreekumari, 6th edi., Pg. 207Vanillyl mandelic acid (VMA) in urineVMA is the main urinary metabolite of the norepinephrine pathway. Metanephrine is acted upon by mono amine oxidase to form(VMA). Normal level of excretion of VMA is 2-6 mg/24 hr.lt is increased in pheochrom...
Biochemistry
Endocrinology
68856c0c-5d8e-4177-abcf-4668132309f8
Oral medication used in the treatment of scabies.
Albendazole
Metronidazole
Ketoconazole
Ivermectin
3d
single
Gama benzene hexachloride 1%lindane 12 -24 hrs a day/2hrs in children .used in caution in infants and children. Permethrin 5%cream -8-12 hrs at night. It act on the nerve cell membrane and disrupt sodium channel current . Used to treat scabies in pregnancy,lctation and infants more than 2 months of age. Benzoyl benzoat...
Dental
Fungal infections, Scabies, Pediculosis
54913cd2-fc2e-401c-8e74-43090a44e37d
A 68-year-old male patient in the cardiology ward complains at each mealtime of difficulty in swallowing (dysphagia). Radiographic studies reveal significant cardiac hypertrophy. A barium swallow, followed by radiographic examination of the thorax, reveals esophageal constriction directly posterior to the heart. Which ...
Mitral valve stenosis
Pulmonary valve stenosis
Regurgitation of the aorta
Occlusion of the anterior interventricular artery
0a
multi
Mitral stenosis leads to left atrial dilation, which can exert a compressive effect on the esophagus. The pulmonary valve is located between the outflow tract of the right ventricle and the pulmonary trunk. The aortic valve is located between the left ventricle and the aorta. Anterior interventricular (left anterior de...
Anatomy
Thorax
80e8b55f-50cf-4d4d-b4e3-9f8bd4fefc68
True about delusions is all except:
They are false belief, but firm.
It is primarily a disorder of perception
Not associated with intellectual background
It remains despite of contrary evidence
1b
multi
DELUSION: Delusion is a false belief in something which is not a fact It persists even after its falsity has been clearly demonstrated. A normal person can have a delusion, but is capable of correcting it by his reasoning power, by his past experience and by being convinced by others. It is primarily a disorder of thou...
Forensic Medicine
Forensic Psychiatry
81ffcdab-6aeb-43f4-954e-8b88fa798992
Aggrecan in
Receptor over platelets
A molecule present in osteoid tissue
Granules in leukocytes
Important component of cartilage
3d
single
Aggrecan is the major proteoglycan component of cartilage. It is composed of several glycosaminoglycans (hyaluronic acid, chondroitin sulfate and keratin sulfate) and both link and core proteins.
Biochemistry
null
19de04f4-3c52-4945-aca2-d11046aabfea
Anterior mesentery gives origin to
Greater omentum
Faciform ligament
Linorenal ligament
None of the above
1b
multi
The pa of the ventral mesentery that attaches to the stomach is known as the ventral mesogastrium. The lesser omentum is formed, by a thinning of the mesoderm or ventral mesogastrium, which attaches the stomach and duodenum to the anterior abdominal wall. The lower pa is dorsal mesentery. ref - BDC 6e vol2 pg235
Anatomy
Abdomen and pelvis
42c090c7-9712-4ec7-bdaa-83b7cf1d7c68
"Iris bombe" occurs due to
Adherent Glaucoma
Anterior Synechiae
Posterior Synechiae
Ring synechiae
3d
single
Posterior synechiae extending for 360 degrees around the pupil (seclusio pupillae), prevent the passage of aqueous from the posterior to the anterior chamber. This gives rise to forward bowing of the peripheral iris causing an 'iris bombe'. This may lead to elevation of IOP due to secondary angle closure by the periphe...
Ophthalmology
All India exam
164f1927-543d-497d-8a53-e4c4338d6fbe
Neisseria infection are associated with ?
Deficiency of early complements
Deficiency of late complements
There is no such association
Any deficiency can be associated
1b
single
Ans. is `b' i.e., Deficiency of late complements
Microbiology
null
6c9531eb-aa57-4724-b359-4f045a7269b3
Signs of graft rejection are all except
Krachmer spots
Khodadoust line
Oedema
Foster spot
3d
multi
D i.e. Foster spot Foster-Fuchs spot, lacquer cracksQ, temporal crescent, lattice degeneration and peripapillary, macular & diffuse chorioretinal atrophy are seen in myopic chorioretinal degeneration.
Ophthalmology
null
193eaf92-45f0-4e2a-aeed-4a1c3577d275
All the following are true about bronchopulmonary aspergillosis except -
Central bronchiectasis
Pleural effusion
Asthma
Eosinophilia
1b
multi
null
Medicine
null
2fabc228-8f44-4693-a466-c370438dfcfa
Exceptions for informed consent are the following, except
Therapeutic privilege
Emergency doctrine
Therapeutic waiver
Therapeutic misadventure
3d
multi
Exceptions for informed consent: Therapeutic privilege Emergency doctrine Therapeutic waiver Loco parentis Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 385
Forensic Medicine
Medical Jurisprudence
c45d997f-1106-4f92-b48f-57d911e76597
Septic arthritis in a 2-year-old child is often caused by –
Hemophilous influenzae
Staphylococcus aureus
Gonococi
Pneumococci
1b
single
Bacteria are the most common pathogens in acute skeletal infections. The microbial spectrum is diverse in suppurative arthritis, but Staphylococcus aureus infection is most common. Salmonella is the most common cause of osteomyelitis in children with sickle cell anemia.
Pediatrics
null
42711992-9a90-4daf-9a3e-9b7bed04b55d
Cell lining of small intestine -
Simple squamous
Stratified squamous
Simple columnar
Stratified columnar
2c
multi
Explainatin 2: The intestinal epithelium is the layer of cells that forms the luminal surface or lining of both the small and large intestine (colon) of the gastrointestinal tract. It is composed of simple columnar epithelium. It has two important functions: absorbing helpful substances and providing a barrier against ...
Anatomy
Digestive System (Histology)
c8a78e2a-3e87-4c66-a322-932df6c567e9
Patient with 37 week AOG, centrally located placenta previa presented with bleeding per vaginum. Management:
Caesarean section
Abortion
Vaccum delivery
Foreceps delivery
0a
multi
Ans. (a) Caesarean sectionRef : D.C. Dutta 8th ed. / 290-92; William's 23rd ed. Chapter 35.* Placenta previa-placenta located at LUS.* One of the most commoncause of APH.* In case of centrally located placenta previa -mode of delivery is always CS.Management of placenta previa depends on its type- 4 typesIndication for...
Gynaecology & Obstetrics
Abortion
fdbbe368-4a13-42e6-8619-2bf4d21f1377
Which of the following techniques in the best for differentiating recurrence of brain tumour from radiation therapy induced necrosis?
MRI
Contrast enhanced MRI
PET scan
CT scan
2c
single
Ans. is 'c' ie PET scan (Ref: Harrison, 16/e, p2460)."MRI or CT scans are often unable to distinguish radiation necrosis from recurrent tumor, but PET or SPECT scans may demonstrate that glucose metabolism is increased in tumor tissue but decreased in radiation necrosis." - Harrison.
Radiology
Neoplasia
bc5c96c1-51cb-480e-bc5e-9e03874b5e2b
A 27 yr old boy has itchy, excoriated papules on the forehead and exposed pas of the arms and legs for 3 years. The disease was most severe in the rainy season and improved completely in winter. What is the most likely diagnosis?
Scabies
Uicaria
Insect bite hypersensitivity
Atopic dermatitis
2c
single
In this case, diagnosis can be made by excluding each option. This patient is least likely to have scabies, as it does not produce lesions on the face in adults. Atopic dermatitis is unlikely since he is giving a history of similar lesions only since 3 years. In atopic dermatitis lesions first appears in infancy and th...
Skin
null
32b51072-add3-4d2a-b72e-8e5c5f6e8fa1
Jean Piaget put forth the theory of
Psychoanalytic theory of psychosexual development
Social learning
Cognitive development
Cultural adaptation
2c
single
null
Dental
null
9faa2bab-0557-4309-aaf8-cd4e50c71fb6
Most important layer of a slow sand filter is -
Vital layer
Sand bed
Filter system
Raw water
0a
single
This is confusing one because of the following statements of Park. "The most important part of the filter is the sand bed" - Park "The vital layer is the heart of the slow sand filter" - Park Following statement may help in choosing the answer : - "Vital layer is the layer that provides the effective purification in...
Social & Preventive Medicine
null
73eb9714-155b-431a-bfcc-27fcbd1f1372
A rickshaw is run over legs of a child making markings of tyre on the legs. Which type of injury is this?
Patterned abrasion
Imprint abrasion
Pressure bruise
Split lacerations
0a
single
Patterned abrasion. Patterning of abrasions The patterning of abrasions is clearer than that of bruises because abrasions frequently take a fairly detailed impression of the shape of the object causing them and, once inflicted, do not extend or gravitate; therefore, they indicate precisely the area of application of fo...
Surgery
null
1bb5263c-3b99-4729-aa24-8b7bcd98f8cb
Asher man n syndrome is secondary to -
Tuberculosis
Endometrial carcinoma
Endometriosis
Submucosal fibroid
0a
single
Ans. is 'a' i.e., Tuberculosis Asherman's syndrome (AS) or Fritsch syndromeo It is a condition characterized by adhesions and/or fibrosis of the endometrium most often associated with dilation and curettage of the intrauterine cavity:o Intrauterine adhesions can also form after infection with tuberculosis or schistosom...
Gynaecology & Obstetrics
Secondary Amenorrhea
e451b103-fbd5-4d6c-9b42-ef75de84c708
What is the age of tendon transfer in post polio residual paralysis -
<6 months
1 year
2 years
>5 years
3d
single
Ans. is 'd' i.e., > 5 years * The available musclepower is redistributed either to equalize an unbalanced paralysis, or to use the motorpower for a more useful function.* It is not done before 5 years of age, asthe child has to be manageable enough tobe taught proper exercises.* More commonlyperformed tendon transfers ...
Orthopaedics
Management In Orthopedics
28be8a71-3e50-4a37-9e55-8870e6f3171f
Alosetron is
5HT1 receptor antagonist
5HT2 receptor antagonist
5HT3 receptor antagonist
Analogues of somatostatin
2c
single
.
Pathology
All India exam
53334b71-2ac3-4243-b130-9e3454858867
Vitamin A prophylaxis is given to children every:September 2007
3 months
6 months
12 months
18 months
1b
single
Ans. B: 6 monthsNational programme for prevention of nutritional blindness focuses onPromoting consumption of vitamin A rich foods by pregnant and lactating women and by children under 5 years of age.Administration of massive doses of vitamin A up to 5 years. First dose of 100,000 IU with measles vaccination at 9 month...
Social & Preventive Medicine
null
e4f17d59-6085-4aeb-83fc-420d92ba7a7c
In comparison to hyperplasia, hyperophy involves?
Increase in cell size and number
Increase in cell size without increase in number
Increase in cell number without increasing in size
Increase in cell size and decrease in number
1b
single
Ans. is 'b' i.e., Increase in cell size without increase in number Hyperplasia Increase in cell number without increasing in size o Occurs due to proliferation of cells Occurs only in cell capable of division DNA content in nuclei is same as normal cells o Example of tissues --> Breast, endometrium, liver, kidney Hyper...
Pathology
null
bdcd5061-814c-4b16-b994-30f67f31c93e
This milestone is achieved by _________
10 months
12 months
16 months
18 months
0a
single
At 10 months Sits up alone and indefinitely without suppo Pulls to a standing position Walks holding furniture Grabs objects with thumb and forefinger Pokes at things with forefingers Uncovers hidden toy Mama, dada sounds (repetitive consonant sounds) Responds to the sound of a name Plays Peek-a-boo Waves bye-bye Ref :...
Pediatrics
Growth and development
d49e9415-6a54-450a-84e2-0a5ec154dda0
Which of the following is used for initial screening of auditory function in a neonate?
Otoacoustic emission (OAE)
Auditory brainstem response (ABR)
Pure tone audiometry (PTA)
Free field audiometry
0a
single
Most screening programmes for newborn hearing ability uses otoacoustic emission as the initial test. It this test fails then auditory brainstem response is used for screening. Otoacoustic emissions are low level sound emitted spontaneously by the cochlea on presentation of an auditory stimulus. Persons with normal hear...
ENT
null
7e8d316f-f50b-4e6e-83c0-00f89e66a079
The recommended oral dose of vitamin A in pregnant females is:
50,000 U
1,00,000 U
2,00,000 U
3,00,000 U
2c
single
Ans. c. 2,00,000 U style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif; margin: 0 0 0 8px; text-indent: 0">'There was a previous recommendation by WHO on giving 2 lacs IU of Vitamin A to pregnant women immediately after delivery, which was withdrawn in 2011.'
Social & Preventive Medicine
Vitamins
ed21d7d4-14f4-4cd7-98ce-7cbc4aab0bba
Contraceptive efficacy expressed as -
100 women months
1000 women years
100 women years
10 women years
2c
single
null
Social & Preventive Medicine
null
baebecd0-0a48-4429-934d-9417da385a14
Not true regarding Sudden infant death syndrome
Also known as cot/crib death
Threefold increase in twins
Incidence common in females
Cigarette smoking by pregnant mothers increase the risk
2c
multi
SIDS / COT DEATH / CRIB DEATH :- It is sudden & unexpected death of seemingly healthy infant whose death remains unexplained even after comp. autopsy. Factors associated with SIDS :- Age = 2 month to 2 years Sex = Male Time = early morning Twins Mother = smoking during pregnancy
Forensic Medicine
Infant deaths & child abuse
a9c9b072-2d17-4b20-9939-5c82038457a2
Which vitamin is given in type 2B familial hyperlipidemia?
Thiamine
Riboflavin
Nicotinic acid
Panthothenic acid
2c
single
Niacin or nicotinic acid is vitamin. Niacin is conveed to its coenzyme forms NAD and NADPTreatment of hyperlipidemia:Niacin (at doses of 1.5 g/day or 100 times the Recommended Dietary Allowance or RDA) strongly inhibits lipolysis in adipose tissue--the primary producer of circulating free fatty acids. The liver normall...
Biochemistry
vitamins
a0b35fd9-8a5b-4084-a81f-8b3f5d046834
Doxylamine used in management of nausea and vomiting is marketed with which vitamin ?
Thiamine
Riboflavin
Niacin
Pyridoxine
3d
single
Ans. is'd'i.e., PyridoxineDoxylamineSedative H1 antihistamine with prominent anticholinergic activity. Marketed in combination with pyridoxine, it is specifically promoted in India for 'morning sickness' (vomiting of early pregnancy), although such use is not made in the UK and many other countries.
Pharmacology
null
f486903d-6d29-4d02-a670-8e7c92c076bb
Maximum tensile strength is recovered in wound area during what period after an injury?
1 to 2 weeks
3 to 4 weeks
6 months
1 year
1b
single
Net collagen accumulation, however, depends not only on increased collagen synthesis but also on decreased degradation. When sutures are removed from an incisional surgical wound, usually at the end of the first week, wound strength is approximately 10% that of unwounded skin. Wound strength increases rapidly over the ...
Pathology
null
aeacc5a4-67b0-4ff1-8143-dc8c8d92b855
Characteristic of acute inflammation is
Vasodilation and increase permeability
Vasoconstriction
Platelet aggregation
Infiltration by neutrophil
0a
single
Ref Robbins 8/e p 45 ,9/e p74 The acute inflammatory response rapidly delivers leuko- cytes and plasma proteins to sites of injury. Once there, leukocytes clear the invaders and begin the process of digesting and getting rid of necrotic tissues. Acute inflammation has two major components (Fig. 2-2): * Vascular changes...
Anatomy
General anatomy
a1852677-a618-48fc-b00a-366721a4c376
A 45-year-old female is diagnosed as a case of pneumococcal meningitis. Her blood sample were sent for culture sensitivity. In the mean time best drug to start as an empirical treatment is -
Penicillin G
Doxycycline
Streptomycin
Vancomyin + Ceftriaxone
3d
single
null
Medicine
null
19304004-9a31-4c89-aefa-7e77073e0624
All are components of GCS EXCEPT:
Eye opening
Respiration
Conversation
Motor response
1b
multi
ANSWER: (B) RespirationREF: Harrison 18t ed table 267-1GLASGOW COMA SCALE 123456EyesDoes not open eyesOpens eyes in response to painful stimuliOpens eyes in response to voiceOpens eyes spontaneouslyN/AN/AVerbalMakes no soundsIncomprehensiblesoundsUttersinappropriatewordsConfused,disorientedOriented,conversesnormallyN/A...
Surgery
Head Injury
8426dea3-1a44-45f6-88fd-a514e762a521
The prognosis of rapidly proliferating glomerulonephritis (Crescentric GN) depends upon -
Number of crescents
Size of crescents
Shape of crescents
Cellularity of crescents
0a
single
null
Medicine
null
0c9af557-7e33-4ba6-9d7a-4c99378ee12c
Deficiency of the 'intrinsic factor of Castle' causes:
Microcytic anemia
Pernicious anemia
Cooley's anemia
Aplastic anemia
1b
single
Answer is B (Pernicious Anemia) Deficiency of Intrinsic factor leads to a specific form of vitamin B12 deficiency megaloblastic anemia called `Pernicious Anemia'. Pernicious Anemia also known as Addison's Anemia is a megaloblastic anemia due to deficiency of intrinsic factor (secreted by parietal cells of gastric mucos...
Medicine
null
e3090a80-f0b0-4e60-9636-15b558084c7d
Urinary incontinence results from all except -
Neurogenic bladder
Vesico vaginal fistula
Ectopic ureter
Rectovesical fistula
3d
multi
Rectovesical fistula doesn’t cause urinary incontinence, as the level of fistula is above the sphincter mechanism.
Surgery
null
1df63d84-9e14-4ea8-9d64-c3082bb31060
Morbid jealousy is most often seen in patients taking
Alcohol
Amphetamine
LSD
Cannabis
0a
single
Some Complications of Alcohol Dependence Medical Complications Central Nervous System: i. Peripheral neuropathy ii. Delirium tremens iii. Rum fits (Alcohol withdrawal seizures) iv. Alcoholic hallucinosis v. Alcoholic jealousy vi. Wernicke-Korsakoff psychosis vii. Marchiaa-Bignami disease viii. Alcoholic dementia ix. Su...
Psychiatry
Substance abuse
b1713ee3-ce97-4d46-86ad-d8ba809b626e
Most common subtype of thyroid cancer is?
Medullary carcinoma
Papillary carcinoma
Follicular carcinoma
Anaplastic carcinoma
1b
single
ANSWER: (B) Papillary carcinomaREF: Sabiston 18th ed chapter 36, Schwartz 9th ed chapter 38Papillary carcinoma is the most common of the thyroid neoplasms and is usually associated with an excellent prognosis, particularly in female patients younger than 40 years. About 70% to 80% of patients in the United States in wh...
Surgery
Thyroid Malignancies
c7644e3c-19eb-4cd4-8cee-a8e1cb38a730
A 35 yr old P 3+0 is observed to have CIN grade III on colposcopic biopsy. Best treatment will be
Cryosurgery
Conization
LEEP
Hysterectomy
2c
single
LEEP Repeat All India 2009 "Although CIN can be treated with a variety of techniques, the preferred treatment for CIN 2 and 3 has become LEE?" - Novak's Gynecology p582 Though the patient is 35 yrs old and has completed her family, still hysterectomy won't be treatment of choice as-"Hysterectomy is currently considered...
Gynaecology & Obstetrics
null
886ed752-2ad3-44bd-b92c-eabe78f57546
Lipschutz inclusion bodies are seen in infects caused by-
Herpes virus
Vaccinia virus
Hepatitis-A virus
Hanta virus
0a
single
Herpes Simplex Viruses Infection Laboratory Diagnosis 1. Light Microscopy - cells from the base of the lesion, or wiped from a mucous surface, or biopsy material, may reveal intranuclear inclusions (Lipschutz inclusion bodies). Infected cells may show ballooning and fusion. 2. Electron Microscopy - Electron microscopy ...
Pathology
miscellaneous
a063d271-5c8b-453d-9ef1-b81dc4304b56
Which of the following antibodies is the most specific for the diagnosis of rheumatoid arthritis?
IgA
IgG
IgM
Anti-CCP
3d
single
Ans. d. Anti-CCP (Ref: Harrison 19/e p2136, 18/e p2745; CMDT 09/727)Anti-CCP antibodies are the most specific blood test for the diagnosis of rheumatoid arthritis."Anti CCP antibodies are the most specific blood test for rheumatoid arthritis (specificity ~95%)."- CMDT 09/727"Anti-cyclic citrullinated peptide (anti-CCP)...
Medicine
Rheumatoid Arthritis
a7d66965-15fb-4922-84da-4d8cfa9e8e4f
Glomus tumour invading the veical pa of the carotid canal. It is
Type B
Type C1
Type C2
Type C3
2c
single
FISCH classification is used for glomus tumours based on the extension into surrounding anatomic structures. Type A tumour - Tumour limited to the middle ear cleft (glomus tympanicum) Type B tumour - Tumour limited to the tympanomastoid area with no infralabyrinthine compament involvement Type C tumour - Tumour involvi...
ENT
Ear
9b56b842-6494-4b63-b9e3-fb342f7bcb87
Na channel mediated TTXN resistant caused is d to involvement of the following:
Nav 1.1
Nav 1.8
TRPI
NMD4
1b
single
null
Biochemistry
null
88752750-864c-49b0-94aa-3c67f31cc188
Dobutamine is preferred over dopamine in cardiogenic shock because of its effect related to:
Better cardiac stimulation
Less peripheral vasoconstriction
Lower risk of cardiac arrhythmias
More CNS stimulation
1b
single
null
Pharmacology
null
eefe8af2-a23a-4436-9da0-2646b2c79c44
An elective surgery is to be done in a patient taking heavy doses of Aspirin. Management consists of :
Proceed with surgery
Stopping aspirin for 7 days and then do surgery
Preoperative platelet transfusion
Intra operative platelet transfusion
1b
single
Ans. is 'b' i.e., Stop aspirin for 7 days and then do surgery "Aspirin should be stopped 1 week before elective surgery." - KDT Aspirin, even in small doses, irreversibly inhibits Thrombooxane A2 (TXA2) synthesis by platelets. Thus it interferes with platelet aggregation and increase the bleeding time. This effect last...
Surgery
null
f7545418-04bd-4daf-8491-ea591ecddb66
A point that falls on horopter excites:
Corresponding retinal points
Crossed diplopia
Confusion
Stereopsis
0a
multi
Ans. Corresponding retinal points
Ophthalmology
null
fef6e97a-cd41-48ac-a3e8-a9273fb9c97e
Xerophthalmia is considered a problem in a community if:-
Night blindness >1%
Bitot spots >1%
Corneal ulceration > 0.05%
Corneal ulcer >0.5%
0a
single
Prevalence criteria for determining the Xerophthalmia problem in a community: Criteria Prevalence Night blindness >1.0% Bitot's spots >0.5% Corneal xerosis / corneal ulceration / keratomalacia >0.01% Corneal ulcer >0.05% Serum retinol >5.0%
Social & Preventive Medicine
Vitamins and Nutritional Deficiencies
4d8d4d4e-aeae-463e-831f-120b89713e99
The predominant immunoglobulin in saliva is
IgA
IgD
IgE
IgG
0a
single
null
Microbiology
null
84658904-3855-47b5-9307-99efb9d90b0d
Nerve supplying Gemellus inferior
Nerve to Obturator internus
Superior gluteal nerve
Inferior gluteal nerve
Nerve to Quadratus femoris
3d
single
Nerve to Obturator internus supplies obturator internus and Gemellus superior. Nerve to Quadratus femoris supplies Quadratus femoris and Gemellus inferior
Anatomy
null
dc8a7e19-52de-4350-b575-d1f8238c27dc
Ca-wheel appearance of tympanic membrane in ASOM is due to
Perforation of tympanic membrane
Edema of tympanic membrane
Congested blood vessels along malleus
Granulation tissue on tympanic membrane
2c
multi
In the stage of presuppuration of ASOM, there is congestion of pars tensa. A leash of blood vessels appears along the handle of malleus and at the periphery of tympanic membrane impaing it a ca-wheel appearance. (Ref: Textbook of diseases of ENT, Dhingra 7th edition; pg no 67)
ENT
Ear
103c7053-4cb6-43a7-88cb-e44cff6062b3
A patient on treatment for leukemia, develops chest pain, pulmonary infiltrates and pleural effusion. The likely cause is :
Daunorubicin
Hydroxyurea
Cytarabine
Tretinoin
3d
single
null
Pharmacology
null
74de58e3-f96c-4d43-916f-942e0926cfe2
Regarding Case Control Study true is
Useful for rare diseases
Incidence can be calculated
Takes longer time
Relative risk can be calculated
0a
multi
(A) Useful for rare diseases # CASE-CONTROL STUDY: Both exposure & outcome have occurred before the start of the study the study proceeds backwards from effect to cause; & it uses a control or comparison group to support or refute an inference.ADVANTAGES AND DISADVANTAGES OF CASE CONTROL STUDIESADVANTAGESDISADVANTAGES1...
Social & Preventive Medicine
Miscellaneous
5eb266b4-596f-4f1b-96d9-2a56f64b4ac8
Laboratory evaluation for the differential diagnosis of chronic myeloproliferative disorders includes all the following evcepr :
Chromosomal evaluation
Bone marrow aspiration
Flow-cytometric analysis
Determination of red blood cell mass
2c
multi
Answer is C (Flow cytometry) respective myeloproliferative disorde Myeloproliferative disorder Useful tests Polycythemia vera Elevated Red cell mass / with normal erythropoetin levels Chronic myeloid leukemia Chromosomal demonstration of Philadelphia chromosome or bcr /abl translocation Chronic idiopathic Myelofibrosis...
Medicine
null
d5c9834e-7024-4229-9bc4-01a8b1944a42
Scabies, an infection of the skin caused by Sarcoptes scabiet, is an example of:
Water borne disease
Water washed disease
Water based disease
Water related disease
3d
single
D i.e. Water related disease Scabies is water washed (category II) water related disease.
Skin
null