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47e6f0e8-32ae-4c0f-9fa1-64caee5fc30d | A patient at 8 weeks pregnancy is diagnosed to have dermoid cyst it should be removed at : | Immediately | At 14-16 weeks | Only when it undergoes torsion | At term along with LSCS | 1b | single | At 14-16 weeks | Gynaecology & Obstetrics | null |
d41b6154-c6db-4a8e-95c5-5bc24b4de39e | A 30-year-old theatre actress developed few wrinkles on the face. The treating physician advised her to have local injections of a drug. This drug is also indicated in cervical dystonia and other spastic disorders like cerebral palsy. Very recently, it has also been approved for prophylaxis of migraine. The physician w... | Hemicholinium | Vesamicol | Botulinum toxin | Physostigmine | 2c | single | Ans. (C) Botulinum toxin(Ref: KK Sharma 2/e p217)As shown in the diagram, the drug is inhibiting the exocytosis of ACh. Botulinum toxin act by this mechanism. Other features pointing towards botulinum toxin are:Anticholinergic adverse effects (dry mouth, blurring of vision)Use in wrinkles, spastic disorders, prophylaxi... | Pharmacology | A.N.S. |
ec7f081a-0417-49b9-98a1-c625ec23b895 | Accumulation of sphingomyelin in lysosome occurs in which disease - | Niemann-Pick disease | Farber's disease | Tay Sach's disease | Krabbe's disease | 0a | single | Ans. is 'a' i.e., Niemann-Pick disease o Gaucher's disease is due to deficiency of b-glucosidase (glucocerebrosidase).DiseaseEnzyme deficiencyLipid accumulatedTay-sach diseaseHexosaminidase AGM2 gangliosideSandoff diseaseHexosaminidase BGM2 gangliosideNiemann-Pick diseaseSphingomyelinaseSphingomyelineFarber's diseaseCe... | Biochemistry | Lipid Oxidation and Synthesis |
87ab8fb0-3d81-4c09-a019-aceb1fc77856 | Saccule develops from | Saccus anterior | saccus medius | Pars superior | Pars Inferior | 3d | single | ref : hazarika 4th ed | ENT | All India exam |
0b947405-4650-40a8-bf75-118a165056ce | Which of the following hallucinations is pathognomonic of schizophrenia | Auditory hallucinations commanding the patient | Auditory hallucinations giving running commentary | Auditory hallucinations criticizing the patient | Auditory hallucinations talking to patient | 1b | multi | Hallucinations are common in schizophrenia. Auditory hallucinations are by far the most frequent, these can be an elementary auditory hallucination (hearing simple words rather than voices), Thought echo, Third person hallucination, Voice commenting on ones on the action. Only the third person hallucinations are believ... | Psychiatry | Schizophrenia and other psychotic disorders |
c25154c7-a460-4b45-aa24-5019cf88c1f4 | Which of the following dietary source contains the lowest percent of linoleic acid? | Coconut oil | Mustard oil | Groundnut oil | Corn oil | 0a | single | <p> Essential fatty acids: Those that cannot be synthesised by humans.They can be derived from food only. The most impoant essential fatty acid is linoleic acid, which serves as the basis for production of other essential fatty acids( linolenic and arachidonic acid) . Not all PUFA are essential fatty acids. Linoleic ac... | Social & Preventive Medicine | Nutrition and health |
355cd91e-bb30-465c-b54b-d45d8053006d | Site of lesion in endocarditis of rheumatic hea disease - | Along lines of closure of valves | Free margin of valves | Both sides of valves | Valve cusps | 0a | multi | Ans. is 'a' i.e., Along lines of closure of valves | Pathology | null |
42252360-5aba-4e59-be5c-2252f515a534 | True Statement about silicosis -a) Produces pleural plaqueb) Associated with tuberculosisc) Lower lobe infiltrationd) Hilar adenopathy | c | d | bd | ac | 2c | multi | Silicosis
Silicosis is a lung disease caused by inhalation of crystalline silicon dioxide (silica).
Currently, it is the most prevalent occupational disease in the world.
Silicosis is a slowly progressive disease, usually presenting after decades of exposure as slowly progressive nodular fibrosing pneumoconiosis.
Sili... | Pathology | null |
ea4a7f36-fee1-4017-8909-eef7b0167758 | What is the % Body surface area involved in burns of the perineum? | 1% | 3% | 5% | 9% | 0a | single | Ans. (a) 1%Ref: Sabiston 19th ed. 1523Perineum involved in burns is 1% of body surface area. | Surgery | Initial Care of the Burn Patient |
8b544ade-d957-47a8-b19c-368636888b69 | Ursodeoxycholic acid is a : | Urinary stone dissolving drug | Thrombolytic drug | Gall stone dissolving drug | Antifibrinolytic | 2c | multi | • Medical therapy for gallstones utilizes bile acids: Chenodeoxycholic acid (CDCA) and Ursodeoxycholic acid (UDCA)
Mechanism of Action
• They inhibit HMG-CoA reductase, the rate limiting enzyme for cholesterol synthesis, thus decreases cholesterol saturation of bile
• They cause dispersion of the cholesterol from the s... | Surgery | null |
994e8efb-e7a7-4eaf-804e-cd2a6b2b6e16 | Best contraceptive method during lactation | IUD | Progesterone only pill (POP) | Lactational amenorrhoea | Barrier method | 1b | single | (B) (Progesterone- only pill) (491- Dutta 6th)POP/MINIPILL* POP is contain very low dose of a progestin Leuonorgestrel, Norethisterone, desogestrel, lynestrenol or norgestrel* It has to be taken daily from the first day of the cycle*** Mechanism of action - it works mainly by making cervical mucus thick and viscous, th... | Gynaecology & Obstetrics | Miscellaneous (Gynae) |
8e3d8b59-248f-4f6b-951c-3024ae184cd9 | Onion peel appearance in X-ray suggests | Osteogenic sarcoma | Ewings sarcoma | Osteoclastoma | Chondrosarcoma | 1b | single | Onion peel appearancne Typical of ---Ewings sarcoma May also be seen in ----Osteosarcoma and osteomyelitis Refer Campbell 13th/e p 953 | Anatomy | null |
f3161ce9-6869-445f-aa2b-42a56d7a40ce | Retinitis pigmentosa patients doesn't have:- | DHA | Eicosa pentaenoic acid | Arachidonic acid | Timnodonic acid | 0a | single | Not all, but many studies have found that patients with retinitis pigmentosa tend to have lower blood levels of DHA (Docosa Hexaenoic Acid, o3, 22:6), an omega -3 fatty acid found in the photoreceptor cells. ADDITIONAL READING ON DHA: Also known as Cervonic acid. This is having 22 C and 6 double bonds (Docosa means 22,... | Biochemistry | NEET 2019 |
4011cf61-225c-439f-8951-0383ee9327ac | Risk factors for preeclampsia:a) Chronic hypertenstionb) Obesityc) Placental ischaemiad) Multigravidae) Antiphospholipid syndrome | acd | ace | cde | ade | 1b | single | null | Gynaecology & Obstetrics | null |
76fd4d1b-9f38-4cc8-a597-9b14cec2df3d | The technique to produce limited removal of epithelial tissue in the sulcus while a chamfer finish line is being created in tooth structure is called | Soft tissue modification | Gingettage | Gingival displacement | Electrosurgery | 1b | multi | null | Dental | null |
75a617dc-002e-4043-808b-7acdfd05597f | Chediak_higashi syndrome is due to defect in | Opsonisation | Chemotaxis | LAD | Extracellular microbacterial killing | 1b | single | Ref Walter and Israel 7/e p150 Chediak Higashi syndrome is an autosomal ressive Condition in which polymorphs exhibit defective random movements , defective chemotaxis and impairee degranulation on phagocytosis paicles | Anatomy | General anatomy |
950da686-0e7c-4e4b-917c-f40bd4d4ae48 | The most abundant group of fibres in the PDL are | Trans-septal | Horizontal | Oblique | Apical | 2c | single | null | Dental | null |
1286873c-5682-4785-b86c-69aa63962f2d | Zero order kinetics is followed by all of the following drugs EXCEPT | Phenytoin | Barbiturates | Alcohol | Theophylline | 1b | multi | Zero order (linear) kinetics; The rate of elimination remains constant irrespective of drug concentration, Clearance decreases with increase in concentration, or a constant amount of the drug is eliminated in unit time, e.g. ethyl alcohol, methanol. The elimination of some drugs approaches saturation over the therapeut... | Pharmacology | General pharmacology |
0d6de076-be13-4370-ae5a-142319ddec72 | Capilary Refill time in child with shock is ? | > 1 second | > 2 seconds | > 3 seconds | > 4 seconds | 2c | single | 1. Capillary refill time (C) * The accepted upper normal time is < 3 sec. * A study of 469 preterm and term healthy neonates at 1-7 days of age demonstrated significant site and observer variations when C was measured on the chest, forehead, palm, and heel. * C is more reliable when measured on the chest but not the fo... | Pediatrics | Fluid and electrolytes |
5a9f4199-cd06-4ced-b8b0-9eff57b3e493 | Most common cause of stridor in children is - | Laryngeal papilloma | Laryngeal web | Laryngomalacia | Vocal cord palsy | 2c | single | null | ENT | null |
0d6852fa-a2b6-45af-8fc4-fb51e0ad06c9 | In G6PD deficiency, which cells are more prone for hemolysis: | Older red cells | Young red cells | Reticulocytes | All are susceptible | 0a | multi | - Mature red cells do not synthesize new proteins - Hence, as red cells ages G6PD enzyme levels fall quickly & becomes inadequate to protect against oxidant stress. - Thus, older red cells are much more prone to hemolysis than younger ones. | Pediatrics | Hemolytic anemia |
22647ee5-b15f-421e-ad3c-a957146cb160 | A 60-year-old man is hit by a pickup truck and brought to the emergency department with a blood pressure of 70/0 mm Hg. Peritoneal lavage showed no blood in the abdomen. The blood pressure is elevated to 85 systolic following the administration of 2 L of Ringer's lactate. An x-ray showed a pelvic fracture. What is the ... | Exploratory laparotomy with packing of the pelvis | CT scan of the pelvis | External fixation of the pelvis | Open reduction and internal fixation (ORIF) of the pelvis | 2c | multi | Early external fixation of the pelvis has been shown to reduce bleeding and mortality in patients in shock consequent to pelvic fractures. An unstable patient should not be sent for a CT scan. Selective angiography with embolization of the bleeding vessel may also be helpful in these patients. Laparotomy usually result... | Surgery | Trauma |
6fa40291-7f15-401f-96fe-cfc7dd4a5926 | The branches of nasociliary nerve include following except | Anterior ethmoidal nerve | Posterior ethmoidal nerve | Supratrochlear nerve | Infratrochlear nerve | 2c | multi | . | Pathology | All India exam |
0a29b088-1e34-4792-9f3c-862cc561c220 | Metabolic acidosis is seen in all except:September 2005 | Diabetic ketaacidosis | Emphysema | Aspirin overdose | Uremia | 1b | multi | Ans. B: EmphysemaMetabolic acidosis occurs when the body produces too much acid, or when the kidneys are not removing enough acid from the bodyDiabetic acidosisHyperchloremic acidosis results from excessive loss of sodium bicarbonate from the body,Lactic acidosis is a buildup of lactic acid-alcohol, cancer, liver failu... | Physiology | null |
715b7559-b990-4825-8ae0-eabce0e8e131 | Palpatory thud, audible slap is seen in | Tracheal foreign body | Bronchial foreign body | Laryngeal foreign body | None | 0a | multi | A sharp foreign body will only produce a cough and haemoptysis. A loose foreign body like seed may move up and down the trachea between the carina and the undersurface of vocal cords causing "audible slap" and "palpatory thud." Asthmatic wheeze may also be present. It is best heard at the patient's open mouth. Ref: PL ... | ENT | Larynx |
bcfd4182-1aa6-45a8-9f9d-92d8ea7c8af5 | Which of the following is known as "Gateway of tears" - | Killian's dehiscence | Rathke's pouch | Waldeyer's ring | Sinus of Morgagni | 0a | single | Inferior constrictor muscle has 2 parts; thyropharyngeus with oblique fibres and cricopharyngeus with transverse fibres. Between these 2 parts, there is a potential gap called as killians dehiscence or gateway of tears as perforation can occur at this site during oesophagoscopy and it is also the site for herniation of... | ENT | null |
05efacf2-26c7-4fc5-acb0-75a922638a3b | Stage of surgical anesthesia during ether administration is | Loss of Consciousness | failure of circulation | Regular respiration to cessation of breathing | Loss of Consciousness to beginning of regular respiration | 2c | single | Guedel's classification is a means of assessing of depth of general anesthesia introduced by Ahur Ernest Guedel for Ether in1937. Stage I (stage of analgesia or disorientation) Stage II (stage of excitement or delirium) Stage III (stage of surgical anesthesia) plane I to IV Stage IV: from stoppage of respiration till d... | Anaesthesia | General anaesthesia |
b747e2c1-572c-47b3-a209-058b88804705 | Source of epistaxis after ligation of external carotid aery is: | Maxillary aery | Greater palatine aery | Superior labial aery | Ethmoidal aery | 3d | single | A, B and C are branches of external carotid aery. If external carotid aery is ligated,the source of epistaxis will be Ethmoidal aery which is a branch of internal carotid aery. Ref Dhingra 6/e,p 178. | ENT | Nose and paranasal sinuses |
ccb341bf-ca41-45ca-b0a4-4e4552dacbcd | Anaphylactic shock is caused by w hich type of hypersensitivity reaction? | I | II | III | IV | 0a | single | Ans. is 'a' i.e., IAnaphylactic shock is caused by type 1 Hypersensitivity reaction. | Pathology | Hypersensitivity Reactions: Immune-Mediated Injury |
8d7dfe30-a605-4368-91f3-1a96bca69eb4 | The most effective buffer system in the blood which is controlled by respiration is: | Bicarbonates | Hemoglobin | Protein | Phosphate | 0a | single | The bicarbonate buffer system is one of the most effective buffer systems in the body because the amount of dissolved CO2 is controlled by respiration (ie, it is an "open" system). Additional control of the plasma concentration of HCO3- is provided by the kidneys. Additional factors that make the carbonic-acid-bicarbon... | Physiology | null |
b263047f-3938-4b63-876d-e93b11903e54 | Genetic risk factors for leukemia are all except- | Down's syndrome | Bloom syndrome | Ataxia telangiectasia | None | 3d | multi | Ans. is 'None' Genetic conditions predisposing to leukemia Down syndrome Diamond-Blackfan anemia Turner syndrome Fanconi syndrome Klinefelter syndrome Neurofibromatosis type 1 Bloom syndrome Schwachman syndrome Paroxysmal nocturnal hemoglobinuria Li-Fraumani syndrome Ataxia - telangiectasia Severe combined immune defic... | Pediatrics | null |
63331488-cd84-431d-81e1-c508edc75ac8 | Oil drop cataract is characteristically seen in - | Diabetes | Chalcosis | Galactosemia | Wilson's disease | 2c | multi | Oil drop cataract is seen in galactosemia. Ref: Clinical ophthamology 2nd/e p.791. | Ophthalmology | Lens |
46f56c63-943b-47fa-8244-19fa90f128ae | A middle aged person presented with the complaints of fear of leaving home, fear of travelling alone and fear of being in a crowd. He develops marked anxiety with palpitations and sweating, if he is in these situations. The most likely diagnosis is:AIIMS 06; NIMHANS 11 | Generalized anxiety disorder | Schizophrenia | Personality disorder | Agoraphobia | 3d | single | Ans. Agoraphobia | Forensic Medicine | null |
f90f5c63-eb4f-4d1c-a41e-6ac6f9ed9083 | What is the mechanism of acute rheumatic fever | Cross reactivity with endogenous antigen | Innocent by slender effect | Due to toxin secretion by streptococci | Release of pyrogenic cytokines | 0a | single | Cross reactivity with endogenous antigen Acute Rheumatic fever results from immune response to group A streptococci. - The main factor responsible for virulence in infection with streptococcal A group is "M" protein. - The body mounts an immune response against streptococci A organism by producing antibodies directed a... | Pathology | null |
3ee6cf84-6bde-42b2-94aa-6de4e28f5ff0 | Facial colliculus covers- | Facial nucleus | Abducent nucleus | Vestibular nucleus | Vagal nucleus | 1b | single | Ans. is 'b' i.e., Abducent nucleus o There is some misprinting in the question. It is abducent nucleus (not abducent nerve) which is covered by facial colliculus.o Facial colliculus is a small elevation in pons, produced by genu (recuring fibers) of facial nerve looping around (covering) abducent nucleus.o Facial colli... | Anatomy | Cranial Nerves |
aa1a626b-6cee-4dc0-b67f-e4ef3bcc6674 | Recently used irrigation solution is: | MTAB | MTAC | MTAD | MTAE | 2c | single | null | Dental | null |
67bfe8a2-4378-4392-a291-212aac6bbda5 | Twin peak sign seen in | Monochorionic Monoamniotic | Monochorionic Diamniotic | Dichorionic Diamniotic | Dichorionic Monoamniotic | 2c | single | Twin peak or lambda sign it is characterized of dichorionic pregnancies and is due to the chorionic tissue between the two layers of the intewin membrane at the placental origin . twin peak appears as a triangle with base at chorionic surface and apex in intewin membrane. | Gynaecology & Obstetrics | JIPMER 2018 |
cc118bb4-b546-47dd-bcbb-b77e11468e29 | Akinesia (hypoactivity) and mutism is a feature of | Twillight state | Stupor | Cataplexy | Torpor | 1b | single | Akinesia + Mutism is a feature of stupor, which is seen in catatonic schizophrenia or catalepsy.
Option c : Cataplexy is sudden loss of muscle tone seen in Norcolepsy, which is not a correct answer. | Psychiatry | null |
5e306217-cc01-4eb2-b891-12d0378bb31a | The pathognomonic sign of neurofibromatosis is | Cafe-au-lait macules | Axillary frekling | Shagreen patch | None of the above | 1b | multi | B i.e. Axillary freckling Neurofibromatosis is autosomal dominantQ disorder. Axillary freckling (crowe sign) is a pathognomic sign of von- Reckling hausen's type 1 neurofibromatosisQ. Cafe - au - lait macules alone are not absolutely diagnostic of NF1, regardless of their size and number. | Skin | null |
fad84ed3-a53c-4a52-9b45-a1b5bf70ee7f | Ataxia telangiectasia is chracterised by all of the following except : | Chronic sinopulmonary disease | Decreased level of a-fetoprotein | Chromosomal breakage | IgA deficiency | 1b | multi | Answer is B (Decreased levels of a fetoproteins) Persistance of very high levels of oncofetal proteins, including alpha fetoproteins and carcinoembryonic antigens is of diagnostic value - Harrison All other features mentioned as options are characteristics of Ataxia-telengiectasia | Medicine | null |
2902211e-e3e0-4a58-997e-dd0290d80bac | Which of the following enzymes inhibit the production of cAMP? | Glucagon | Angiotensin II | ACTH | Beta-Adrenergics | 1b | single | Cyclic AMP was the first intracellular second messenger signal identified in mammalian cells. Different peptide hormones can either stimulate (s) or inhibit (i) the production of cAMP from adenylyl cyclase, which is encoded by at least nine different genes. Hormones that Inhibit Adenylyl Cyclase (HI) and the production... | Biochemistry | null |
781a48cb-2842-4dc4-8da4-4d98c23f13a0 | What is the mechanism of action of sacubitril? | ACE inhibitor | Neutral endopeptidase inhibitor | Endothelin antagonist | Angiotensin receptor blocker | 1b | single | Ans. b. Neutral endopeptidase inhibitorRef: CMDT 2018/P 414Sacubitril is a neutral endopeptidase or neprilysin inhibitor approved for treatment of chronic CHF in combination with angiotensin receptor blocker like valsartan.It can cause angioedema and hence is contraindicated with ACE inhibitors or within 36 hours of us... | Pharmacology | C.V.S |
49a9b6c2-562d-4062-ae65-7a770fc8a6fe | A man presents with fatigue. Hemogram analysis done suggested low Hb, high MCV. The next investigation is? | Vit B12/folatelevels | Bone Marrow | S. Iron studies | Reticulocyte count | 3d | single | Ans. (d) Reticulocyte count(Ref: Robbins 9th/pg 645-648)This is a tricky question as the initial investigation looks like B12 /folate levels, as the patient has macrocytosis.But remember, Macrocytosis can also be seen in hemolytic anemia, as newer RBC precursors released are larger in size.So the initial investigation ... | Pathology | Misc. (R.B.C) |
39fbda06-cc67-4b76-9301-030e5a38e319 | Tumors of the minor salivary glands are most frequently found at the: | Upper lip. | Lower lip. | Palate. | Tongue. | 2c | single | Palate is the most common site. | Surgery | null |
58ae8ec0-a556-4aa6-940c-44864b6fe207 | Which of the following is true regarding pulp component of PUFA? | Detected without use of probe | Pus drainage with swelling | Sinus tract detected with pain | Ulceration with pulp involvement | 0a | multi | PUFA index by Monse et al (2010)
The PUFA index records the presence of severely decayed teeth with:
Visible pulpal involvement - (P/p)
Ulceration caused by dislocated tooth fragments - (U/u)
Fistula - (F/f)
Abscess - (A/a).
Pediatric Dentistry Principles and Practice
M.S.Muthu | Dental | null |
e2b0394c-7982-4535-80f3-b2d24f2ce30a | The earliest immunoglobulin to be synthesized by the fetus is - | IgA | IgG | IgE | IgM | 3d | single | Option 1, 3, 4 IgM: IgM is the first immunoglobulin to be synthesized by a neonate in about 20 weeks of age. IgM is not transpoed across the placenta; hence, the presence of IgM in the fetus or newborn indicates intrauterine infection. The first immunoglobulin produced in response to an antigen is IgM. after 3 monts of... | Microbiology | Immunology Pa 1 (Immune Response, Antigen-Antibody Reactions, Hypersensitivity, Structure of Immune System, Immunodeficiency Disorders) |
8b326ca4-01cf-4c22-8a41-29efe2b25985 | Dissociative Fugue is characterised by | Wandering away from home | Irreversible amnesia | Gradual recovery | Normal recall | 0a | multi | Dissociative Disorders result after emotional trauma, conflicts over unacceptable urges or impulses Dissociative Identity Disorder*: multiple personality disorder, alters, the self-states presence of two or more distinct identities or personality states that recurrently take control of the individual's behavior accompa... | Psychiatry | All India exam |
22bb7f44-2046-4c62-866c-c300cb31dcd4 | Deficiency of which of the following enzymes is associated with Tyrosinosis: | Tyrosine aminotransferase | 4-Hydroxyphenylpyruvate dioxygenase | Homogentisate oxidase | Fumarylacetoacetate hydroxylase | 3d | single | Tyrosinosis is synonymous with Type-1 Tyrosinemia and is caused by a deficiency of Enzyme Fumarylacetoacetate hydrolase. Tyrosine Catabolic pathway and Associated Disorders: Tyrosine aminotransferase 4-Hydroxyphenylpyruvate dioxygenase Homogentisate oxidase Fumarylacetoacetatehydrolase Tyrosine aminotransferase Tyrosin... | Biochemistry | Metabolism of protein and amino acid |
b5bc6eb4-94b0-418d-84dc-17b69618c52e | NKX3-1 immunohistochemical used for diagnosis of? | Colorectal carcinoma | Pancreatic carcinoma | Prostate | Renal cell carcinoma | 2c | single | NKX3-1 expression acts as a transcription factor that has been found to play a main role in prostate development and tumor suppression. The loss of NKX3-1 expression is frequently observed in prostate. Other markers for prostate cancer are:- PSA(prostate specific antigen) AMACR Urinary PCA 3 TMPRSS2 | Pathology | Ovaries & prostate gland |
bae61c53-47e4-4981-8a73-a0b2a28134d8 | 'Square root' sign is characteristic of | Dilated cardiomyopathy | Restrictive cardiomyopahty | Constrictive pericarditis | Contractile dysfuncation seen in which type of cardiomyopathy? | 2c | single | square root sign is a charecteristic feature of Constrictive pericarditis Dip & plateau pattern' or 'square root sign': Early diastolic filling of the ventricles is unimpeded and abnormally rapid, but late diastolic filling is abbreted and halts abruptly when total cardiac volume expands to the volume limit set by the ... | Medicine | C.V.S |
dfe9ad73-a5eb-411a-a960-fe0ef5c6eefa | 3 year old girl has a central incisor removed because of
trauma. What is the best appliance to use to replace the
missing tooth? | A removable appliance | Fixed lingual wire with a tooth attached | A fixed lingual wire only | Hawley appliance with replacement tooth | 1b | single | null | Dental | null |
c7c7071e-6d15-407c-a4e5-d6257bababea | The epithelioid cell and multinucleated giant cells of Granulomatous inflammation are derived from which of the following cells? | Basophils | Eosinophils | CD4-T lymphocytes | Monocytes - Macrophages | 3d | single | Granulomatous inflammation is a characteristic feature of Type IV hypersensitivity reaction against tubercle bacilli. When ceain non degradable antigen such as tubercle antigen is present, the initial perivascular mononuclear cell monocyte infiltrate is replaced by macrophages over a period of 2-3 weeks. The accumulate... | Pathology | null |
9ff808a7-4e6b-490c-85a0-fd8603fad951 | Best uterine relaxation is seen with: | Chloroform | Nitrous oxide | Ether | Halothane | 3d | single | Halothane inhibit intestinal and uterine contractions. This propey is used for facilitating external or internal version during late pregnancy. However it&;s use during labour can prolong delivery bad increase postpaal blood loss. Muscle relaxation is minimal with nitrous oxide. Rest of the drugs donot have uterine con... | Pharmacology | Anesthesia |
2fe0cb1f-d9a5-4cc3-9175-e15badf2596e | Which of the following drugs can cause malignant hypehermia? | Succinyl choline | Halothane | Lidocaine | All the above | 3d | multi | Mepivacaine, Gallamine, Methoxy flurane, Ethyl chlonde etc also cause malignant hypehermia. | Pharmacology | null |
7910881f-ab27-4122-aad9-b3ef4ce6c651 | A typical febrile seizure is characterized by all Except | Male children are more prone | Occurs with sudden rise in temperature | Manifests with paial seizures | Phenobarbitone prevents fuher attacks | 2c | multi | FEBRILE SEIZURES:Febrile seizures are defined as seizures which occurring during fever.Febrile seizures are the commonest cause of seizures in childhoodMost common age of presentation is 6 months to 5 yearsOccurs at the sudden rise of core temperature.Recurrence rate is 30-50%Types: typical and atypical febrile seizure... | Pediatrics | All India exam |
d5abcaa3-6d11-4539-8f63-16ca46e68d30 | Thiamine deficiency causes decreased energy production because? | It is required for the process of transamination | It is co-factor in oxidative reduction | It is co-enzyme for transketolase in pentose phosphate pathway | It is co-enzyme for pyruvate dehydrogenase | 3d | single | null | Biochemistry | null |
fc0cdccc-7c32-4920-ba95-743156fafea9 | Erb's point is: | C4, C5 | C5, C6 | C6, C7 | C7, C8, T1 | 1b | single | C5, C6 | Anatomy | null |
4b81253b-0d97-4cf8-9404-80a3bab8261e | CA-19-9 is seen in all except | Breast carcinoma | Ovarian carcinoma | Colonic carcinoma | Pancreatic carcinoma | 0a | multi | (A) Breast carcinoma # CA19-9: CA19-9 is a monoclonal antibody generated against a colon carcinoma cell line to detect a monosialoganglioside found in patients with gastrointestinal adenocarcinoma.> It is found to be elevated in 21 to 42 percent of cases of gastric cancer, 20 to 40 percent of colon cancer, and 71 to 93... | Pathology | Misc. |
51584959-0f2a-4021-9063-aa1dca16c009 | Treatment of Ca larynx in stage. T1MoNo is - | Radiotherapy | Surgery total laryngectomy | Laser therapy | Microlaryngoscopic surgery | 0a | single | null | ENT | null |
3ffa53b5-3afc-489d-9d9f-2916c01fac5d | The complex process of leukocyte movements through the blood vessels are all EXCEPT - | Rolling | Adhesion | Migration | Phagocytosis | 3d | multi | Ans. is 'd' i.e., Phagocytosis | Pathology | null |
c38d8526-fd7c-44a9-9773-937d88486686 | A 30-year old HIV positive patient presents with fever, dyspnoea and non-productive cough. Patient is cyanosed. His chest X-ray reveals bilateral, symmetrical interstitial infiltrates. Which of the following is the most likely diagnosis? | Tuberculosis | Cryptococcosis | Toxoplasmosis | Pneunocystis carinii pneumonia | 3d | single | This HIV positive patient is showing clinical features and X-ray findings suggestive of pneumocystis carnii pneumonia. PCP infection occur in HIV positive individuals with CD4 count less than 200. It is an oppounistic fungal pulmonary pathogen that is an impoant cause of pneumonia in the immunocompromised host. Ref: Ha... | Medicine | null |
6df104e7-eb8d-49cb-9854-6bd6bcc53757 | Most common cause of cholangitis - | Viral infection | CBD stone | Surgery | Amoebic infection | 1b | single | Gall stones are the most common cause of obstruction in cholangitis.
Other causes are
benign & malignant strictures
parasites
instrumentation of the ducts and indwelling stents
partially obstructed biliary enteric anastomosis
Most common organisms cultured from bile in patients with cholongitis include
Escherichia ... | Surgery | null |
18f8a6f3-e19e-4bc4-b07a-7afbae2eecfd | In human corneal transplantation, the donor tissue is | Synthetic polymer | Donated human cadaver eyes | Donated eyes from live human beings | Monkey eyes | 1b | single | B i.e. Donated human cadaver eyes Donor corneas are harvested from cadaveric donors within 6 hours after death Q (upto 12 hours after death in cold countries.) Corneal Transplantation (Grafting) /Keratoplasty General Indications To provide a clear visual axis and restore good vision (Optical Keratoplasty) To restore th... | Ophthalmology | null |
d4f62b1b-9379-413a-b7bf-dbe46e753c66 | Which of the following condition is associated with normal anion gap metabolic acidosis? | Cholera | Starvation | Lactic acidosis | Ethylene glycol poisoning | 0a | single | A normal anion gap metabolic acidosis is caused by the loss of bicarbonate with a reciprocal increase in chloride concentration. It is also known as hyperchloremic acidosis. It most commonly results from abnormal gastrointestinal or renal losses of HCO3-. Diarrhea is the most common cause of hyperchloremic metabolic ac... | Medicine | null |
b3015310-851f-4410-bfcd-1a79eb2abfdf | A 25-year-old sexually active woman complains of purulent discharge and dysuria after having intercourse with a new paner. Most sensitive investigation for diagnosis: | Grams staining | Bacterial growth or culture on selective media | Wet mount | Nucleic Acid Amplification Test (NAAT) | 0a | multi | Ans. d. Nucleic Acid Amplification Test (NAAT) Most sensitive investigation for diagnosis in a 25 year old sexually active woman who complains of purulent discharge and dysuria after having intercourse with a new paner (sexually transmitted urethritis) is Nucleic Acid Amplification Test (NAAT). `Gonorrhea and chlamydia... | Skin | null |
2e57482b-1b66-4415-8ba1-9f38fac0c2f9 | A large for gestational age baby delivered at 40 weeks was observed to be lethargic. The Blood sugar was measured to be 35mg/dl. The management is __________ | Foified Breast Milk | 10% IV Dextrose | Oral Glucose Solution | Normal saline | 1b | single | .A plasma glucose level of less than 30 mg/dL (1.65 mmol/L) in the first 24 hours of life and less than 45mg/dL (2.5 mmol/L) thereafter constitutes hypoglycemia in the newborn. Dextrose also has medical purposes, Because dextrose is a "simple" sugar, the body can quickly use it for energy. Simple sugars can raise blood... | Pediatrics | New born infants |
9afcd80f-6e62-4380-9c8e-7753e6cc2194 | The following are realated to bromocriptine therapy except : (Irrelevant Question) | It is used to inhibit inappropriate lactation with secondary amenorrhea | It is specific in suppressing only the prolactin secretion | If pregnancy occurs there is increased incidence of multiple pregnancy | Its teratogenic effect on the fetus is inconclusive | 2c | multi | Bromocriptine A synthetic ergot derivative and powerful dopamine agonist It supress prolactin while promoting the secretion of gonadotropins, hence induces menstruation, ovulation and promotes pregnancy. It also suppresses lactation USES Supression of lactation Cyclical mastalgia Anovulatory infeility Pituitary Microad... | Gynaecology & Obstetrics | PCOD, hirsutism and galactorrhea |
2b544534-f1f6-442b-82c4-0ec08799ba67 | Threshold level of herd immunity for Peussis is | 80% | 70% | 90% | 50% | 2c | single | Ans. is 'c' i.e., 90% Advantage of herd immunity o It is not necessary to achieve 100% immunization to control a disease by providing herd immunity. o When a ceain percentage of population, is vaccinated, the spread of disease is effectively stopped. o This critical percentage is referred to as herd immunity threshold.... | Social & Preventive Medicine | null |
a6d2756f-3a3f-411e-9439-6cb0ff5b6189 | Sibutramine belongs to which group of drugs according to it's indication of use? | Antipsychotic | Antihypeensive | Anti-Obesity | Anti-Diabetic | 2c | single | Sibutramine is a centrally acting anorectic drug which was used as anti obesity drug. The target site of action is ventromedial and lateral hypothalamic regions in the CNS. It functions as a serotonin and nor epinephrine reuptake inhibitor. It was withdrawn from US market in October 2010, due to an increased risk of no... | Pharmacology | null |
1f78b4ab-d93b-4f29-8a4e-d7d9cac19f76 | The term "Dementia precox" was coined by | Freud | Bleuler | Kraepelin | Schneider | 2c | single | C i.e., Kraepelin Benedict Morel used term demence precoce (in french) for deteriorated patients whose illness began in adolescence. Emil Kraeplin translated it into dementia. PrecoxQ i.e. dementia = deteriorated cognitive process & precox = early onset Eugen Bleuler coined term schizophreniaQ Kahlbaum described catato... | Psychiatry | null |
899eff7f-a810-4383-b4d3-ab747c568d05 | True about rhinophyma: | Premalignant | Common in alcoholics | Acne rosacea | Fungal etiology | 2c | multi | Rhinophyma is a slow-growing benign tumor which occurs due to hyperophy of the sebaceous glandsdeg of the tip of the nose.Seen in long standing cases of acne rosacea.Mostly affects men past middle age.Presents as a pink, lobulated mass over the nose.TreatmentParing down the bulk of the tumor with a sharp knife, or carb... | ENT | null |
6950df0d-d379-48a9-896a-e8c02f6fb9b2 | Most common cause of neuropathic joint - | Leprosy | Tabes dorsalis | Diabetes | Nerve injury | 2c | single | Ans. is 'c' i.e., DiabetesNeuropathic joint (Charcot's joint)o It is a progressive destructive arthritis associated with loss of pain sensationx, proprioception or both, in addition normal muscular reflexes that modulate joint movements are decreased.o Without these protective mechanisms, joints are subjected to repeat... | Orthopaedics | Neuropathic Joints |
bbc2a9c1-7d65-4b12-a6c2-ad3a7e53f360 | Preferred material for femoro popliteal bypass- | Dacron | PTNE | Saphenous vein | Gortex | 2c | single | null | Surgery | null |
3aa8424d-28de-4787-b363-ce845a59ccc1 | Most appropriate treatment for acute paranychia | Paial nail removal | Nail removal | Lifting of eponychium | Incision and drainage | 0a | single | .ACUTE PARONYCHIA * It is the most common hand infection. * It occurs in subcuticular area under the eponychium. * Minor injury to finger is the common cause. * Suppuration occurs very rapidly. * It tracks around the skin margin and spreads under the nail causing hang nail or floating nail. * Organisms are Staphylococc... | Surgery | Urology |
bdb49294-7250-46ae-8321-ddb32b7456a9 | Larval form of which parasite resides in muscle - | Taenia saginata | Echinococcus | Trichuris | All of the above | 3d | multi | Larval form of trichuris ,taenia saginata,echinococcus resides in muscle | Microbiology | parasitology |
3a5a96de-f41c-46b5-af69-95d9f745126a | Foci of granulomatous inflammation show all of the following except? | Eosinophils | Epithelioid cells | Fibrosis | Lymphocytes | 0a | multi | Ans- (a) EosinophilsRef: Robbiris pathology 9th ed. /97* A special form of chronic inflammation is seen in response to tissue invasion by Mycobacterium tuberculosis.* Macrophages and multinucleated giant cells accumulate about the organisms, and fibrous tissue form about these small focal lesions or tubercles.* This co... | Pathology | Cellular Pathology |
2b48797b-e786-4f0a-b9e9-1ec7f4bb08dc | Triple negative breast cancer- What is true - | It has good prognosis | There are no receptors postitve for ER, PR and HER2 NEU | It is a cancer that cannot be diagnosed by triple assessment | Three Radiologic investigations ic CT scan, MRI and USG are needed for diagnosis | 1b | multi | Ans. is 'b' i.e., There are no receptors postitve for ER, PR and HER2 NEU o Triple-negative breast cancer refers to any breast cancer that does not express the genes for estrogen receptor (ER), progesterone receptor (PR) or Her2/neu. This makes it more difficult to treat since most chemotherapies target one of the thre... | Surgery | Breast Cancer - Prognosis and Follow-Up |
378272cf-64fd-4f75-b137-8a4c10c9e0c3 | Single skin lesion is seen in which type of leprosy - | LL | TT | BL | BT | 1b | single | null | Microbiology | null |
a80bf51b-6b81-413a-af79-3c17f89836ce | A 67 year old lady is brought in by her 6 children saying that she has gone senile. Six months after her husband's death she has become more religious, spiritual and gives lots of money in donation. She is occupied in too many activities and sleeps less. She now believes that she has a goal to change the society. She d... | Depression | Schizophrenia | Mania | Impulse control disorder | 2c | single | Kindly don't get confused with the fact that the symptoms are following husband's death. Even negative life events can precipitate manic episode. This patient has increased religiosity, overspending, increased activity levels, decreased sleep, new interests and goals and lack of insight. All these symptoms are suggesti... | Psychiatry | Mood Disorders |
0d0ccf67-f33d-4662-9b5d-54b27f6c0d64 | A 14 year old boy having lost his father a year ago, is caught shoplifting. The boy will be sent to - | An orphanage | An anganwari | A prison | A remand home | 3d | single | parks textbook of preventive and social medicine 23rd edition * in remand homes ,the child is placed under the care of doctors,psychiatrists and other trained personnel.every effos is made to improve mental and physical well beiing of the child .elementary schooling is given,various as and crafts are taught,gaames are ... | Social & Preventive Medicine | obstetrics,pediatrics and geriatrics |
d901fd9b-3b46-43d2-b24f-1895a593b8ef | The most important regulator of serum 1,25 (OH)2 vitamin D concentration is: | Serum calcium | Serum magnesium | Serum 25 (OH) vitamin D | Parathyroid hormone | 3d | single | A major function of parathyroid hormone is to act as a trophic hormone to regulate the rate of formation of 1,25(OH)2 vitamin D. The mechanism by which parathyroid hormone exerts this effect may be secondary to its effects on phosphorus metabolism. Other hormones, including prolactin and estrogen, also may playa role ... | Unknown | null |
0413e275-d5a3-4533-a121-10511017b5fd | Which of the following tendons passes below the sustenticulum Tali - | Tibialis Anterior | Tibialis Posterior | Flexor digitorum longus | Flexor hallucis longus | 3d | multi | Tendon of flexor hallucis longus passes below sustenticulum tali. | Anatomy | null |
92d02631-6740-429f-bd53-f3b6e64175c3 | Hypercalcemia is NOT seen in - | Primary hyperparathyroidism | Tumour lysis syndrome | Multiple sclerosis | Sarcoidosis | 1b | single | tumor lysis syndrome is characterized by hyperuricemia, hyperkalemia, hyper phosphate moa, and hypocalcemia .caused by destruction of large number of rapidly proliferating neoplastic cells.acidosis may develop.acute renal failure occur frequently. Hyperuricemia may be present at time of chemotherapy. The finding of uri... | Medicine | Endocrinology |
181fb4f3-d5ab-42e5-949f-c2149d0fd2ce | The most common aspect in gold inlay and amalgam cavity design is | Axiopulpal bevel | Gingival bevel | Occlusal bevel | Axiofacial bevel | 1b | single | The gingival bevel removes the unsupported enamel and compensates for casting shrinkage. It is a feature of resistance form. Reverse bevel is given in inlay for lap sliding fit. It locks the restoration and prevents proximal displacement. | Dental | null |
19895b5a-7caa-48c0-ad15-4bd87f669344 | Atracurium is excreted by | Renal excretion | Hepatic elimination | Nonenzymatic degradation | All of the above | 2c | multi | Ans. is 'c' i.e., Nonenzymatic degradation The unique feature of atracurium is inactivation in plasma by spontaneous nonenzymatic degradation (Hofmann elimination) in addition to that by alkaline ester hydrolysis. Consequently its duration of action is not altered in patients with hepatic / renal insufficiency or hypod... | Anaesthesia | null |
d0d522c0-33cc-4828-844b-6770e1b2f537 | Which water soluble vitamin is synthesized in our body - | Niacin | Folic acid | Cobalamine | Pyridoxine | 0a | single | Ans. is 'a' i.e., Niacin o This question is confusing one (Read text below)o Niacin (Vitamin B3) is synthesized from tryptophan inside the bodo Some vitamins are also formed by bacterial activity in coloni) Vitamin Kii) Vitamin B12Thiamin (Vitamin Bl)iv) Riboflavin (Vitamin B2)v) Biotin (Vitamin B7)o Thus, options a, b... | Biochemistry | Vitamins |
0eeff703-ebe8-42f3-9dc6-b628e030ec99 | Vision 2020-Right to sight by WHO targets all except: September 2009 | Cataract | Trachoma | Epidemic conjunctivitis | Onchocerciasis | 2c | multi | Ans. C: Epidemic conjunctivitis VISION 2020 is the global initiative for the elimination of avoidable blindness, launched in 1999, jointly by the World Health Organization (WHO) and the International Agency for the Prevention of Blindness (IAPB) with an international membership of NGOs, professional associations, eye c... | Ophthalmology | null |
969647be-6e6a-470d-b51e-a99f8a747492 | Ceruloderma is characterised by- | Excess melanin in dermis , pigmentation not accentuated under Wood's lamp | Excess melanin in basal and suprabasal layers, pigmentation accentuated under Wood's lamp | Increased epidermal and dermal melanin | Excess melanin in basal and suprabasal layers, pigmentation not accentuated under Wood's lamp | 0a | single | Ceruloderma- Due to defect in migration of melanocyte. Melanocyte derived from neural crest and migrate to stratum basale (epidermis) Defect in migration of melanocytes due to which they remain in dermis Eg. Of Ceruloderma - 1. Mongolian spot 2. Nevus of OTA3. Nevus of ITO Clinical features - Dermis- Blue lesion - Don'... | Dental | Hyper Pigmented Disorders |
0030feb4-e1af-46e3-a61d-0e22462393c6 | The mechanism of action of Enteropathogenic E.coli is - | Adherance to enterocytes | Stimulates adenyl cyclase | Produces secretory diarrohea | None of the above | 0a | multi | Ans. is 'a' i.e., Adherance to enterocytes . EPEC adheres to the mucosa of upper small intestine and causes disruption of the brush border microvilli. The name enteroadherent E. coli has been proposed for these strains, which can be indentified by their adhesion to HEP-2 cells. | Microbiology | null |
2126dc93-f76a-46de-9b4f-bc5c6e3f515f | Which of the following endocrine tumors is most commonly seen in MEN I | Insulinoma | Gastrinoma | Glucagonoma | Somatostatinoma | 1b | single | Ans. is 'b' i.e., Gastrinoma | Medicine | null |
c2df8d48-cc49-417f-bf2a-6ae3ee95edfe | Most common cause of breech presentation: | Contrcted pelvis | Hydramnios | Prematurity | Oligohydramnios | 2c | single | Prematurity | Gynaecology & Obstetrics | null |
2840b848-af54-41b2-8c26-1c877024490c | All of the following are therapeutic uses of penicillin G, except | Bacterial meningitis | Rickettsial infection | Syphilis | Anthrax | 1b | multi | Ans. is 'b' i.e., Rickettsial infection Penicillin G is the DOC for 1. Meningococcal meningitis 7. Leptospira 2. Bacillus anthracis (anthrax) 8. Actinomyces israelii (Actinomycosis) 3. Clostridium perfringens (gas gangrene) 9. Borrel i a burgdorferi (Lyme disease) 4. Clostridium tetani (tetanus) 10. Enterococci 5. Cory... | Pharmacology | null |
4c8541ed-eea6-4c08-a330-87a900adf122 | A patient was on treatment with penicillin. He developed pallor but there was no shoness of breath, uicaria or wheezing. On investigation, antibodies against penicillin were found in his blood. What is the type of hypersensitivity reaction that most likely occurred in this patient? | Type I hypersensitivity | Type II hypersensitivity | Type III hypersensitivity | Type IV hypersensitivity | 1b | multi | Ans. b. Type II hypersensitivity | Medicine | null |
21917de2-a170-4613-87cb-b78a6cd5d735 | Hynes pharyngoplasty is used to improve a child's ? | Appearance | Teething | Speech | Feeding | 2c | single | Ans. is 'c' i.e., Speech | Surgery | null |
cfdeea99-ec03-4ede-98c1-41971cdbfc4a | In HSP gross hematurea is seen in what % of children? | 5 - 10% | 10 - 20% | 20 - 30% | 30 - 40% | 2c | single | Ans. is 'c' i.e., 20 - 30% Henoch-schonlein_purpura (HSP) Small vessel vasculitis Purpuric rash Ahritis Abdominal pain Glomerulonephritis Gross hematuria is seen in 20-30% of cases | Pediatrics | null |
086aeee0-2851-42e7-860e-e9451dd213bf | Features of Horner's syndrome include all of the following except- | Miosis | Ptosis | Anhydrosis | Exopthalmos | 3d | multi | There is enophthalmos (not exophthalmos). | Ophthalmology | null |
167501c1-7b49-4744-a5b6-7358acae4efe | Ferritin biosynthesis is regulated by serum level of ? | Ceruloplasmin | Hepcidin | Iron | Transferrin | 2c | single | Ans. is `c' i.e., Iron"The level of iron in plasma is sensed by specific iron regulatory proteins which control the rate offerritin synthesis and to maintain homeostasis" - Human physiologyHepicidin regulates absorption of iron. But, it is also according to the serum iron level. If serum iron is deficiem, hepacidin lev... | Physiology | null |
30fd59d4-aeb3-428c-b70c-af7a79ab49bd | The standard normal distribution | Is skewed to the left | Has variance = 1.0 | Has standard deviation = 0.0 | Has mean = 1.0 | 1b | single | Normal Distribution:
Is also known as ‘Gaussian distribution’ or ‘Standard distribution’
Type of distribution: Is the distribution of values of a quantitative variable such that they are symmetric with respect to a middle value with same mean, median and mode, and then the frequencies taper off rapidly and symmetrical... | Social & Preventive Medicine | null |
96770f3d-307b-4ae3-a93e-1e1e02e3fa5c | Spanish windlass is practiced in Spain as a method of execution, it is a type of | Bansdola | Mugging | Garrotting | Hanging | 2c | single | In Spanish Windlass, an iron collar is tightened by a screw for strangulation. It is an example of garrotting where the victim&;s throat may be grasped or a ligature is thrown over the neck & quickly tightened by twisting it with a lever, which result in sudden loss of consciousness & collapse Reff: The synopsis of for... | Forensic Medicine | Asphyxia |
924a49ba-0a3c-4fab-8ea3-69ab9b017cd3 | Most common site for peripheral aneurysm is: | Popliteal | Profunda femoral | Femoral | External iliac | 0a | single | Ans: A (Popliteal) Ref: Robbins Pathologic Basis of Disease, 8th edition & Harrison online Chapter 249.Explanation:"Popliteal artery aneurysms are the most common peripheral artery aneurysms".Popliteal Artery AneurysmPopliteal artery aneurysms are the most common peripheral artery aneurysms.Approximately 50% are bilate... | Pathology | Aneurysms and Dissections |
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