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f8815d77-f060-4c18-beea-52dab61f7281 | The most common tumour of cerebellopontine angle is | Meningioma | Acoustic neuroma | Neurofiroma | None of the above | 1b | multi | Acoustic neuroma comprises 80% of all cerebellopontine angle tumours. Ref: Textbook of diseases of ENT, PL Dhingra, 7th edition, pg no. 125 | ENT | Ear |
e408bfe3-f6ac-45f1-887f-d7bc84755822 | In community-acquired acute bacterial sialadenitis, the most common causative pathogen is: | S. aureus | S. albus | S. salivarius | None of the above | 0a | multi | In community-acquired acute bacterial sialadenitis, the most common causative pathogen is S. aureus, which can be eradicated using an antibiotic with Gram-positive coverage such as amoxicillin with clavulanate or clindamycin. | Pathology | null |
77efb28d-6aa1-4b74-b57a-73e15b1b071d | DOC for ventricular arrhythmias due to digitalis toxicity is: | Lignocaine | Quinidine | Amiodarone | Verapamil | 0a | single | Ventricular arrhythmias due to digitalis toxicity Lidocaine i.v. repeated as required is the drug of choice It suppresses the excessive automaticity but does not accentuate A-V block Quinidine, Procainamide, and propafenone are contraindicated Note: Lignocaine is DOC but 2nd alternative option is Phenytoin for digitali... | Pharmacology | Hypeension, Arrhythmias, Dyslipidemia |
02f404ad-056f-4288-b5a5-1ac89748491c | Power of a study can be increased by- | Increasing a error | Decreasing ss error | Decreasing a error | Increasing ss error | 1b | single | <p> Decreasing ss error. Reference:Simple Biostatistics by Indrayan & Indrayan,1stbedition,page no: <\p> | Social & Preventive Medicine | Biostatistics |
2544eaa8-a265-431b-8ad7-7a93d1ef129d | Note true about Japanese encephalitis | Transmitted by culex mosquito | Caused by group A arbovirus | Pig is amplifier host | Man is incidental host | 1b | multi | Ans. b. Caused by group A arbovirus | Microbiology | null |
693fe465-25c8-4f22-837a-a4377cb85b94 | All of the following statements are true about repair of groin hernias except: | Lichtenstein tension free repair has a low recurrence rate | TEP repair is an extraperitoneal approach to laparoscopic repair of groin hernia | In Shouldice repair, non-absorbable mesh is used | The surgery can be done under local anesthesia in selected cases | 2c | multi | Ans. (c) In shouldice repair, non absorbable mesh is usedRef: Sabiston 19/e p1120-1126* Lichtenstein uses Tension free prolene mesh (procedure of choice for Inguinal hernia)* TEP repair - Total Extra Peritoneal repair* Shouldice- Anatomical repair- Double breasting of Fascia transversalis done* Hernia Surgeries are don... | Surgery | Hernia |
56d9f5dc-9219-4db2-847f-46fef27b229d | A 23 years old female patient presented with sever diffuse hair fall for last 1 month. She had a major accident with severe blood loss 5months back for which she had to be hospitalized for 1 month. She is very anxious that all her hair will fall. Most likely diagnosis is? | Alopecia aerate | Telogen effluvium | Anagen effluvium | Androgenetic alopecia | 1b | multi | Ans. is 'b' i.e., Telogen effluvium Points in favor arei) Diffuse hair fallii) History of accident with blood loss (stress)iii) Hair loss after 5 months of accident | Skin | Alopecia |
bde0f28d-d1d7-49ef-8e42-e0990539176c | Which of the following is not affected by a lesion in posterior column of spinal cord: | Romberg's sign | Temperature sense | Vibration sense | Ataxia | 1b | single | Answer is B (Temperature sense): Temperature sense is a feature of the spinothalamic tract and not the posterior column. Vibration & Joint position sense are transmitted the posterior column. Altered joint position sense may lead to Ataxia and a positive Romberg's sign. | Medicine | null |
71af0c12-7f37-4493-bebb-5624861d89dd | . A 45 year male with a history of alcohol dependence presents with confusion, nystagmus and ataxia. Examination reveals 6th cranial nerve weakness. He is most likely to be suffering from: | Korsakoff's psychosis | Wernicke encephalopathy. | De Clerambault syndrome | Delirium tremens | 1b | single | B i.e. Wernicke encephalopathy | Psychiatry | null |
1afdee0e-7613-4068-b3a3-559370c8530b | Post Kidney transplantation complication caused by CMV is? | Parotitis | Cholecystitis | Pyelonephritis | GI Necrosis and stricture | 2c | single | The answer here is simple as the pyelonephritis is the only option related to kidney. The impoant point to revise here is that CMV in transplant patients is the a complication of immunosuppression SIDE EFFECTS OF NON SPECIFIC IMMUNOSUPPRESSION 1) INFECTION : bacterial and fungal infections are most common , risk greate... | Surgery | Urology |
11bae4c3-e222-4d88-84d1-b16810b0774e | Total Iron required per day for pregnancy period:- | 65 mg/day | 35 mg/day | 25 mg/day | 70 mg/day | 1b | single | Group Recommended intake (mg/day) Man 17 Woman (non-pregnant) & lactating women 21 Pregnancy 35 | Social & Preventive Medicine | RDA, Nutritional Requirements |
6ab6deac-a1d0-490c-8bad-637246fb9cbd | Oral combined contraceptive pills contain which one of the following sets of hormones? | Ethinyl estradiol, progestogen, and estrone | Progestogen and ethinyl estradiol | Progestogen and estrone | Estrone and ethinyl estradiol | 1b | single | null | Unknown | null |
c2cccbf1-7893-426b-ba09-1f8a93b08589 | A study of peripheral blood smears shows that neutrophil nuclei of women have a Barr body, whereas those of men do not. The Barr body is an inactivated X chromosome. Which of the following forms of RNA is most likely to play a role in Barr body formation? | lncRNA | mRNA | miRNA | siRNA | 0a | single | There are forms of noncoding RNA that play a role in gene expression. Long noncoding RNA (lncRNA) segments greater than 200 nucleotides in length can bind to chromatin to restrict access of RNA polymerase to coding segments. The X chromosome transcribes XIST, a lncRNA that binds to and represses X chromosome expression... | Pathology | Cellular Pathology |
dc1556e2-6830-490d-b16e-1df2214fb9ed | Anti topoisomerase 1 is marker of | Systemic sclerosis | Classical polyaeritis nodosa | Nephrotic syndrome | Rheumatoid ahritis | 0a | single | Ref Robbins 9/e p228 B cell activation also occurs, as indicated by the pres- ence of hypergammaglobulinemia and ANAs. Although there is no evidence that humoral immunity plays a signifi- cant role in the pathogenesis of SS, two of the ANAs are viually unique to this disease and are therefore useful in diagnosis (Table... | Anatomy | General anatomy |
90022d5e-decc-4628-9722-5fbcc79b6ee9 | The patient gives history of putting tobacco in buccal vestibule and chewing betel quid, the lesion is: | Pan chewer’s lesion | Tobacco pouch keratosis | Leukoplakia | Both 1 and 2 | 3d | multi | Tobacco pouch keratosis: A white, wrinkled change of the mucosa in the mandibular buccal vestibule secondary to the use of chewing tobacco.
This lesion consists of a thick brownish black encrustation on the buccal mucosa at the site of placement of the buccal quid. It is often seen among heavily addicted betel quid che... | Pathology | null |
abbcad0b-ffbe-4174-aa48-eef5bed96b21 | Marker for granulocytic Sarcoma- | CD33 | CD38 | CD117 | CD137 | 2c | single | Answer is option 3,CD117 kit, a proto-oncogene, encodes the transmembrane tyrosine kinase receptor CD117 and is detected by flow cytometry in the majority of cases of acute myeloid leukemia. The prognostic significance of the presence of c-Kit in acute myeloid leukemia is debated. Granulocytic sarcoma is a primary or s... | Pathology | Haematology |
56924b3d-df28-4e4c-b73a-e425211be8cc | Thoracic duct does NOT drain: | Right upper pa of body | Left upper pa of body | Right lower pa of body | Left lower pa of body | 0a | single | Right upper quadrant of the body drains the lymphatics into the right lymphatic duct and rest of the body drains into thoracic duct Thoracic duct is continuation of cysterna chyli as it pass through aoic hiatus begin at lower border of T12 . At T5(angle of louis) it crosses to left side and drains at left Jugulo-subcla... | Anatomy | Back and Thorax |
25528b65-065a-4f67-95e1-82246032ad75 | All the following are seen at Transpyloric Plane except | Pylorus of Stomach | Hilum of Kidney | Body of Gall Bladder | Neck of Pancreas | 2c | multi | The transpyloric plane is an imaginary transverse plane often referred to in anatomical descriptions.The transpyloric plane of Addison passes midway between the suprasternal notch and the pubic symphysis. It lies roughly a hand&;s breadth below the xiphisternal joint. Anteriorly, it passes through the tips of the ninth... | Anatomy | Abdomen and pelvis |
45a46a3a-f789-470d-89b6-26f529b6f571 | 100% moality disease, incidence and prevalence relationship will be; | P = 1 | P > 1 | P < 1 | No relationship | 2c | single | Prevalence = Incidence x Duration Duration= Prevalence/Incidence - longer the duration of the disease, the greater its prevalence. - if the disease is acute and of sho duration either because of rapid recovery or death, the prevalence rate will be relatively low compared with the incidence rate. (P < 1). | Social & Preventive Medicine | FMGE 2019 |
9d8bb96b-48cd-48ca-9d3b-ba5bcc19abf8 | Urinary anion gap is? | Plus 1 | 0 | Minus 1 | Cannot be calculated | 1b | single | Urinary anion gap (Na+ + K+ ) - (Cl- ) = 0 Urine is electro neutral *Anion gap in Blood = (Na+) - (Cl- + HCO3-) | Medicine | Fluids and Electrolyte Imbalance |
f9e237f3-3af8-4004-9ca5-5f7610409290 | Esophagus enters through | Central tendon of diaphragm | Along aoic opening | Muscular pa of diaphragm | All | 2c | multi | C. i.e. Muscular pa of diaphragm | Anatomy | null |
f9212b70-18d9-4d93-8c81-dfce19636d84 | Which of the following is true of lepromatous leprosy a) Bacterial index + to ++ b) Involvement of earlobes c) Symmetrical involvement d) Only a few bacilli are seen in the lesion e) Loss of eyebrows | abc | bce | ade | cde | 1b | multi | null | Medicine | null |
4bf60488-1574-4a3e-af43-5966598a85f6 | All can cause recurrent pulmonary infection except: | VSD | Recurrent LVF | TOF | ASD | 2c | multi | Answer is C (TOF) ASD, L VF and VSD are all associated with pulmonary congestion and hence predispose to pulmonary infections. TOF is associated with reduced pulmonary blood flow (oligenic lung fields) due to right ventricular outflow obstruction and hence does not predispose to recurrent pulmonary infections. | Medicine | null |
a6a1d8c8-c830-4409-982b-c0670e47f57a | All of the following structures are derived from mesonephric duct, EXCEPT: | Vas deferens | Ureter | Trigone of urinary bladder | Prostatic utricle | 3d | multi | The wolffian duct or mesonephric duct forms the epididymis, vas deferens and seminal vesicles. Testosterone directs the development of wolffian duct. Trigone of the bladder develop from the caudal end of the mesonephric duct. A pair of ureteric bud grow upwards from the distal mesonephric duct near its inseion into the... | Anatomy | null |
2dc39fab-a599-48b6-894d-56b312fa111e | For each mol of substrate oxidized Complexes I, III, and IV in the respiratory chain NADH, --- mol of ATP are formed? | 1 | 1.5 | 2 | 2.5 | 3d | single | For each mol of substrate oxidized Complexes I, III, and IV in the respiratory chain (ie, NADH), 2.5 mol of ATP are formed per 0.5 mol of O2 consumed; ie, the P:O ratio = 2.5. On the other hand, when 1 mol of the substrate (eg, succinate or 3-phosphoglycerate) is oxidized Complexes II, III, and IV, only 1.5 mol of ATP ... | Biochemistry | Respiratory chain |
c1918fdf-25c8-4d69-b842-1c14554798f6 | All of the following are Eradicable disease except | Tuberculosis | Guinea worm | Polio | Measles | 0a | multi | Till date only one disease has been eradicated - SMALLPOX. Diseases that are amenable to eradication are measles, diphtheria, polio and guniea worm. Ref : Park&;s Textbook of Preventive and Social Medicine; 23rd edition; Page 94 | Social & Preventive Medicine | Concept of health and disease |
99e82eb7-6059-47d6-96f3-83b2bfb8dae6 | Power driven instrument is | Gates glidden drill | Reamers | Giromatic | Racer-Engine | 0a | single | null | Dental | null |
422c1eb2-1a0e-4093-b8f8-65fd02fa8911 | In pyogenic liver abscess commonest route of spread is | Hematogenous through poal vein | Ascending infection through biliary tract | Hepatic aery | Local spread | 1b | single | Routes of spread 1st most common - Biliary tract 2nd most common - poal vein | Anatomy | G.I.T |
f3ceafd1-03ea-4f60-963d-33fbae8c9df7 | Which of the following organs is not involved in hemochromatosis? | Liver | Hea | Testis | Pancreas | 2c | single | Hereditary hemochromatosis is an adult-onset disorder that represents an error of iron metabolism characterized by inappropriately high iron absorption resulting in progressive iron overload and accumulation of iron in parenchymal organs, leading to organ toxicity.This is the most common inherited liver disease in whit... | Medicine | null |
8b5402cc-27db-429e-94d9-e59cd2ad2c82 | Most impoant component of Bishop score | Position | Dilatation | Station | Effacement | 1b | single | The most impoant component of bishop score is dilatation of cervix | Anatomy | General obstetrics |
8ba68e16-5216-4c93-bca5-7f238f114a82 | Most sensitive investigation for diagnosis of asymptomatic chlamydial infection:aEUR' | Culture | Nucleic acid amplification | Serology | Direct microscopic examination of tissue scraping | 1b | single | Nucleic acid amplification Chlamydial infections are frequently asymptomatic. - Confirmation of chlamydial infection usually depends on taking an appropriate clinical sample .from the patient ,followed by the direct detection of the organism using a suitable laboratory-based diagnostic test. The demonstration of chlamy... | Microbiology | null |
cc98f0d7-f862-4dab-a009-f0037c253d9c | The histologic entity that has the worst prognosis in interstitial lung disease is: | Non-specific interstitial pneumonia | Desquamative interstitial pneumonia | Acute interstitial pneumonia | Usual interstitial pneumonia | 2c | single | Ans: c (Acute interstitial pneumonia)Ref: Rosai and Ackerman's Surgical Pathology 9th ed Pg. 377, Harrison 18th ed chp 261Acute Interstitial Pneumonia (Hamman-Rich Syndrome)* A fulminant form of lung injury characterized by idiopathic ARDS and organizing diffuse alveolar damage by lung biopsy.* The onset is usually abr... | Unknown | null |
ac407b63-d4d4-49c0-b3d2-8330801555d2 | JAK-2 mutation is strongly associated with? | Burkitt's lymphoma | Polycythemia vera | Multiple myeloma | Mantle cell lymphoma | 1b | single | Ans. is 'b' i.e., Polycythemia vera * Janus kinase 2 (JAK2), a member of the Janus kinase family, is a non-receptor tyrosine kinase.* JAK2 fusions with the TEL(ETV6) (TEL-JAK2) and PCM 1 have found to be associated with leukemia, particularly clonal eosinophilia forms of the disease.* JAK-2 mutations are associated wit... | Pathology | Blood |
d8239459-b332-4d68-8b30-ebd3f57cd612 | A 32-year old adult male broke the jaw of another in an alleged fight. The investigating police officer: | Can arrest him only after procuring warrant | Can arrest him without warrant | May declare him hostile and put him in jail | May declare him sociopath and send him to mental asylum | 1b | multi | Ans. b. Can arrest him without warrant Fracture or dislocation of mandible is a 'Grievous injury' for which punishment is defined under IPC 325. It is a 'cognizable offence' hence a police officer can arrest the accused without warrant. "Cognisable offence: An offence for which a police officer can arrest a person with... | Forensic Medicine | null |
ecec99d4-0f36-4764-9cfa-bdc4ac084ac1 | In an emphysematous patient with bullous lesions, which is the best investigation to measure lung volume: | Body Plethysmography | Gas dilution | Transdiaphragmatic pressure | DLco | 0a | single | Answer is A (Body Plethysmography): Body Plethysmography is the investigation of choice fir estimating lung volumes in the setting of COPD with bullous lesions (trapped air) Estimating Lung Volumes Gas Dil ion Technique (Helium / Nitrogen Dilution Method) Gas dilution methods are fairly accurate in measurement of lung ... | Medicine | null |
325b78f1-31f0-4e8a-af95-d8d50101bbc8 | Bisphosphonates are not used in: | Hypercalcemia | Osteoporosis | Cancer induced osteolysis | Vitamin D intoxication | 3d | single | Vitamin D intoxication | Pharmacology | null |
2f1cc76d-1bda-4941-84d0-ef464596a301 | A 20 yrs aged patient, presents in coma with pin point pupils and fasciculations but no fever. Most probable diagnosis is: | Head injury | Dhatura | Pontine haemorrhage | Organophosphorus poisoning | 3d | single | D i.e. Organophosphorus poisoning Pinpoint pupils (miosis) is seen in 'Bar Car OR Mor - Chlor' i.e. Barbiturates, Carbolic acid (Phenol), Organophosphorus, Morphine (Opioid), Choral hydrate.Q & Pontine haemorrhageQ So we are left with two options - Pontine haemorrhage & Organophosphorus. Not useful in Carbamate poisoni... | Forensic Medicine | null |
aa9e0daf-f78e-4e95-a160-11c1e1dc587e | In family welfare programme, score of 1 is given to: | Birth rate | Net reproduction rate | Achievement of goal | Total implementation of programme | 1b | single | Ans. is 'b' i.e. Net reproductive rate NRR of 1 is equivalent to attaining approx., the 2 child norm*The Govt, of India in 1983 adopted the policy of attaining a NRR of 1 by the year 1996 (now to be achieved by 2006). | Social & Preventive Medicine | Demography |
760f5697-5318-4c30-a1c0-e09a6c0e3943 | Foamy macrophage is formed by - | LDL | HDL | Oxidized LDL | Oxidized HDL | 2c | single | Ans. is 'c' i.e., Oxidized LDLo Foam cells are lipid laden cells that derive predominantly from macrophages, but smooth muscle cells can also imbibe lipid to become foam cells.o Macrophages and endothelial cells generate oxygen free radicals that induce chemical change in LDL to yield oxidized (modified) LDL.o Oxidized... | Pathology | Histo Pathology |
52f6ee1b-c721-411e-a0d0-3eff35879ec4 | Dye for myelography is injected in? | Subdural space | Epidural space | Subarachnoid space | Extradural space | 2c | single | Ans. c (Subarachnoid space). (Ref. Clark, Positioning in Radiography, 10th ed., 588)MYELOGRAPHY# Myelography is the radiographic investigation of the spinal canal for the diagnosis of space occupying & obstructive lesions & requires the contrast agent to be injected into the subarchnoid space (which lies between pia ma... | Radiology | Nervous System |
aa3f686e-468e-4a3a-ac58-f8d41f2aa132 | Treatment for mild ptosis is- | Fasanella servat operation | Levator resection | Frontalis sling operation | Everbusch's Operation | 0a | single | *Fasanella-Servat operation. It is performed in cases having mild ptosis (1.5-2mm) and good levator function. In it, upper lid is eveed and the upper tarsal border along with its attached Muller's muscle and conjunctiva are resected. Ref: Khurana 7th/e p.395 | Ophthalmology | Diseases of orbit, Lids and lacrimal apparatus |
523326bc-fe56-4c06-b19d-4a64feb3a3f0 | Rash is not caused by ? | Salmonella | Shigella | Meningococci | Staphylococcus | 1b | single | Ans. is 'b' i.e., Shigella Salmonella (typhoid) and meningococci cause morbiliform rash. Staphylococcus causes scarlentiform rash in TS S and SSSS. Infections causing Exanthems (acute generalized rash) Morbilliform Viral : Measles (rubeola), rubella, erythema infectiosum, EBV, CMV, adenovirus, echovirus, early HIV, cox... | Microbiology | null |
90120236-907a-4065-8657-34da37055af5 | Ligament preventing the displacement of humerus is | Coracoclavicular | Coracohumeral | Coracoacromial | Glenohumeral | 3d | single | The area between the superior and middle glenohumeral ligament is a point of weakness in the capsule( foramen of Weitbrecht) which is a common site of anterior dislocation of humeral head. Reference : page no:147,BD chaurasia- upper limb& thorax, 7th edition. | Anatomy | Upper limb |
edbc33a9-9bb2-4c7d-ba77-d867412ffde6 | True about Dressler's syndrome is all, except : | Occurs with in hours after myocardial infarction | Recurrence may be seen | Chest pain is common | Responds well to salicylates | 0a | multi | Answer is A (Occurs with in hours after myocardial infarction) Dressler's syndrome develops after an interval of 1 to 4 weeks (or even month) following cardiac injury (MI) and not within hours. Dressler's syndrome / Post Cardiac Injury Syndrome Dressler's syndrome refers to an acute farm of pericarditis that develops a... | Medicine | null |
6b637ee8-0476-44aa-99fa-2e2124c09de8 | Wide and fixed 2nd heart sound seen in - | ASD | VSD | Aortic stenosis | PDA | 0a | single | (A) (ASD) 632. Davidson 21st (1922 - 24 - H 19th)Atrial septal defect* Wide fixed splitting of the second heart sound wide because of delay in right ventricular ejection (increased stroke volume and right bundle branch block) and fixed because the septal defect equalizes left and right atrial pressures throughout the r... | Medicine | C.V.S. |
3d795a0e-7c30-4278-bb77-8f53fdf275d4 | Ivacaftor was approved by FDA in 2018 for | Cystic fibrosis | Migraine | Hypeension | Glycogen storage disorders | 0a | single | Ivacaftor is used for treating cystic fibrosis | Pharmacology | All India exam |
45fddbe1-5644-4dbb-9e11-eec420418754 | One of the most common side effects of inhaled beclomethasone dipropionate is: | Pneumonia | Oropharyngeal candidiasis | Atrophic rhinitis | Pituitary adrenal suppression | 1b | single | (Ref: KDT 6/e p225) Most common adverse effect of inhaled coicosteroids is oropharyngal candidiasis. Pituitary adrenal suppression is less likey with inhalational route of coicosteroids than with oral route. | Pharmacology | Other topics and Adverse effects |
f6c0a096-3608-415c-99d0-3a4958d6c586 | All of the following are associated with proximal muscle weakness except – | Spinomuscular atrophy | Duchenis muscular dystrophy | Polymyositis | Myotonic dystrophy | 3d | multi | The general rule in that :
Myopathies have proximal muscle weakness.
Neuropathies have distal muscle weakness.
Myotonic dystrophy is an exception to this general rule and mainly involves the distal muscles. Also, know
The difference between myopathy and muscular dystrophy.
Myopathy
Any skeletal muscle disorder that c... | Pediatrics | null |
fa180203-1346-4615-9aa1-d3f47340b046 | Insulin does not facilitate glucose uptake in the following except : | Liver | Hea | RBC | Kidney | 1b | multi | B i.e. Hea | Physiology | null |
03596924-87f8-477d-8b0b-546a95950c39 | The electrical potential difference necessary for a single ion to be at equilibrium across a membrane is best described by the | Goldman equation | van't Hoff equation | Fick's law | Nernst equation | 3d | single | At normal body temperature (37degC), the electrical difference that will balance a given concentration difference of univalent ions--such as Na+ ions--can be determined from the following formula, called the Nernst equation.Ref: Guyton; 13th edition; Chapter 4 Transpo of Substances Through Cell Membranes | Physiology | General physiology |
327bac05-518c-4c0c-b6df-87485609de7d | Which one of the following ligaments contains splenic artery - | Gastrosplenic ligament | Splenocolic ligament | Splenorenal ligament | Splenophrenic ligament | 2c | single | Linorenal (splenorenal) ligament contains tail of pancreas, splenic vessels, lymph nodes and lymphatics and sympathetic nerve. | Anatomy | null |
370f65fc-f5ae-4e4b-8bb2-fb5dbcd32f06 | The non poisoning Salt of cyanide is : | Potassium cyanide | Hydrocyanic acid | Sodium cyanide | Potassium ferroc yanide | 3d | single | D i.e. Potassium ferrocyanide | Forensic Medicine | null |
d6a35c91-5899-46de-9d71-60b6cd131157 | α - intercalated cells are present in _________ helps in __________ | Distal convoluted tubule, HCO3– secretion | Distal convoluted tubule, H+ secretion | Collecting duct, H+ secretion | Collecting duct, HCO3– secretion | 2c | single | Intercalated cells are present in Collecting duct
I cells are of 2 types.
Alpha : acid secretion
Beta : HCO3 secretion | Physiology | null |
4116a0c4-a0e4-48e6-acdb-189b25db75c4 | M.C. retroperitoneal tumour is - | Fibrosarcoma | Liposarcoma | Dermoid cyst | Rhabdosarcoma | 1b | single | Ans is 'b' ie Liposarcoma The most common primary malignancy of the retroperitoneum is sarcoma.(Ref Sabiston) "In the retroperitoneal location, well-differentiated and dedifferentiated liposarcoma and leiomyosarcoma are the most common histiotypes, whereas in the visceral location, GISTs are found most commonly."- Devi... | Social & Preventive Medicine | null |
e6a9b479-6407-4acf-ab8e-90bf8c4b7c0b | Hydrolysis of which of the following compounds yield urea? | Ornithine | Argininosuccinate | Aspartate | Arginine | 3d | single | Arginine is an amino acid that is deaminated to form ornithine primarily in the liver as part of the urea cycle. Ornithine, argininosuccinate, aspartate and citrulline are generated in the urea cycle but do not provide free ammonia for urea synthesis. | Biochemistry | null |
66e36868-979b-433b-9826-3c27eed88e01 | Mild mental retardation is defined when IQ is- | 50-70 | 35-49 | 20-34 | <20 | 0a | single | Ans. is 'a' i.e., 50-70 CategoryIQMild50-70Moderate35-49Severe20-34Profound<20 | Social & Preventive Medicine | Social Science, Mental Health & Genetics |
69dca969-55d0-4574-a203-1740b3228daa | Histology of acute rejection of renal transplant are- | Aeriolar hyalinosis | Eosinophilic infiltration | Glomerular vasodilation | Neutrophilic infiltration | 3d | single | Harshmohan textbook of pathology 7th edition. *in hyper acute rejection there are numerous neutrophils around dialated and obstructed capillaries which are blocked by fibrin and platelet thrombi. *in acute rejection there is extensive infilteration in interstitium of the transplant by lymphocytes and a few plasma cells... | Pathology | General pathology |
b3726d86-8727-4d6b-b33c-07de2d709c06 | The hormone associated with cold adaption is: | Growth hormone. | Thyroxine. | Insulin. | Melanocyte Stimulating Hormone | 1b | single | B i.e. Thyroxine | Physiology | null |
3ca29e32-90e5-40b5-adaf-9119fe864a41 | Which of the following does not cross a blood brain barrier | Pralidoxime | Obidoxime | Diacetylmonoxime | Physostigmine | 0a | single | Ref-Katzung 11/e p121 Pralidoxime or 2-PAM, usually as the chloride or iodide salts, belongs to a family of compounds called oximes that bind to organophosphate-inactivated acetylcholinesterase. It is used to treat organophosphate poisoning in conjunction with atropine and diazepam | Pharmacology | Autonomic nervous system |
b0f60cde-5ffa-4f74-b9e4-00cfc6a31bf8 | Marker for Hairy cell Leukemia is: | CD 30 | CD 103 | CD1 | CD4 | 1b | single | CD 103 | Pathology | null |
d8d50d0b-a7e8-4f93-81ea-24515f1c6833 | All of the following drugs are used in Opioid dependence, except | LAAM | Buprenorphin | Methadone | Nalorphine | 3d | multi | (D) Nalorphine # Opioid dependence> Levomethadyl acetate> Levomethadyl acetate, also known as levo-a-acetylmethadol (LAAM) is a synthetic opioid similar in structure to methadone.> It has a long duration of action due to its active metabolites.> It was approved for use in the treatment of opioid dependence.> Indication... | Psychiatry | Miscellaneous |
e0d28304-c51e-4948-9c06-748934a723c9 | Platelet aggregation is caused by - | Nitrous oxide | Thromboxone A2 | Aspirin | PGI2 | 1b | single | Robbins basic pathology 9th edition page no 46, Answer is option 2, thromboxaneA2 Thromboxane A2 is a potent platelet aggregating agent and a vasoconstrictor, is the major prostaglandin produced in these cells. Itvis an intrmediate produced in the cyclooxygenase pathway by the enzyme thromboxane synthase. | Pathology | Haematology |
f43e9739-0a1d-4c89-be3b-a84dc5e8269b | Gold standard investigation for screening breast carcinoma in patients with breast implant - | MRI | USG | Mammography | CT scan | 0a | single | Ans. is 'a' i.e., MRI o It can be useful to distinguish scar from recurrence in women who have had previous breast conservation therapy for cancer (although it is not accurate within 9 months of radiotherapy because of abnormal enhancement).o It is the best imaging modality for the breasts of women with implants,o It h... | Surgery | Breast Cancer - Prognosis and Follow-Up |
312af99f-ba2b-4ab3-9c04-0aec1663295c | Murphy sign is seen in: March 2013 (g) | Acute pancreatitis | Acute appendicitis | Acute cholecystitis | Acute esophagitis | 2c | single | Ans. C i.e. Acute cholcystitis Murphy's sign It is useful for differentiating pain in the right upper quadrant. Typically, it is positive in cholecystitis, but negative in choledocholithiasis, pyelonephritis and ascending cholangitis. | Surgery | null |
ce41aef7-8aca-4b2f-a993-825aff799df0 | All of the following structures forms the boundary of the Hesselbach's triangle, EXCEPT? | Rectus muscle | Inguinal ligament | Inferior epigastric vessel | Deep circumflex iliac vessel | 3d | multi | Hesselbach's triangle is a region in the anterior abdominal wall. It is bounded inferiorly by the inguinal ligament, medially by the lateral border of the rectus muscles, and laterally by the inferior epigastric vessels.Base of the triangle is formed by pubic pecten and pectineal ligament. | Anatomy | null |
3f3a0746-67b3-4be9-b894-ad7e5886c2e3 | The recommended target HbA1C to minimise the risk of vascular complications in diabetic individual is | 10% or more | 8% | 7% or less | 9% | 2c | single | null | Medicine | null |
6c42610f-f16f-46a4-a941-e5eaf133db2b | A young female patient came for routine examination. On examination a mid systolic click was found. There is no history of RHD. The histopathological examination is most likely to show | Myxomatous degeneration and prolapse of the mitral valve | Fibrinous deposition on the tip of papillary muscle | Rupture of chordae tendinae | Aschoff nodule on the mitral valve | 0a | single | Ans. a. Myxomatous degeneration and prolapse of the mitral valve | Pathology | null |
f9ee5718-6ce5-4028-a9c2-1d4e61029d6e | Most common testicular tumour | Seminoma | Teratoma | Seoli cell tumour | Chorio ca | 0a | single | Seminoma is the most common germ cell tumor of the testis or, more rarely, the mediastinum or other extra- gonadal locations. It is a malignant neoplasm and is one of the most treatable and curable cancers, with a survival rate above 95% if discovered in early stages. | Anatomy | Urology |
06230cf0-22a7-4e3c-8fec-944022f94eef | All except one are absorbed in the DCT: | Water | Potassium | Chloride | Sodium | 1b | multi | Although K+ is also absorbed in DCT, secretion of K+ may exceed K+ absorption in this segment. So, B should be the most appropriate answer. | Physiology | null |
aab097c4-282f-47b5-a1e6-24809e2c8319 | Subarachnoid hemorrhage blood is collected mostly in which pa of the skull - | Basal cistern | Around Fah carebri | Near cerebellum | Tentorium | 0a | single | Answer- A. Basal cisterncausative factor-Exclude underlying aneurysmal ruptureTypical location-Basal cisternsClinical profileHeadache,meningismusdelayed manifestations,vasospasm | Surgery | null |
a23d0f4d-6485-4fd2-b492-5ba9f9e19c0f | Not a layer of retina: | Outer limiting membrane | Retinal pigment epithelium | Bowman's membrane | Ganglion cell layer | 2c | single | Layers of the retina, from the outside inwards Retinal Pigment Epithelium Layer of rods and cones External (Outer) limiting membrane Outer nuclear layer Outer plexiform layer Inner nuclear layer Inner plexiform layer Ganglion cell layer Layer of optic nerve fibres Internal (Inner) limiting membrane The neural retina me... | Anatomy | null |
d92d357b-22b3-422b-8c73-799e412f01d0 | Which of the following statement regarding water reabsorption in the tubules? | The bulk of water reabsorption occurs secondary to Na+ reabsorption | Majority to facultative reabsorption occurs in proximal tubule | Obligatory reabsorption in ADH dependent. | 20% of water is always reabsorbed irrespective of water balance | 0a | multi | Water reabsorption occurs along with sodium reabsorption.Ref: Ganong&;s review of medical physiology; 24th edition; page no: 685 | Physiology | Renal physiology |
d2c651fc-b16e-40b6-9b07-688bc8ac0614 | A man 25-yrs-old presents with renal failure. His uncle died of renal failure 3 yrs ago. On slit lamp examination, keratoconus is present. Diagnosis is - | ADPCKD | ARPCKD | Aloport's syndrome | Denysh-Drash syndrome | 2c | single | null | Medicine | null |
8a612f97-7227-4fe2-bc4e-c920ca0674e4 | In a fetus, testis lies at superficial inguinal ring at: | 6th month | 7th month | 8th month | 9th month | 2c | single | Ans. C 8 monthsRef: Netter's Clinical Anatomy, 3rd ed. pg. 325Descent of testis3rd monthIliac fossa7th monthDeep inguinal ring7th monthTransits through inguinal canal8th monthSuperficial inguinal ring9th monthEnters the scrotum | Anatomy | Embryology |
92353c07-f3e0-4492-91d4-7121edb744f9 | Which of the following is not a sequelae of trachoma? | Proptosis | Tylosis | Pseudocyst | Dacrocystitis | 0a | single | Proptosis REF: Khurana 4th ed p. 66 Sequelae of trachoma: Lids : entropion, tylosis, ptosis, madarosis , ankyloblepharon Conjuctiva: concretions, pseudocyst, xerosis, symblepharon. Cornea: opacity, ectasia, xerosis. Others: Dacrocystitis, chronic dacryoadenitis. | Ophthalmology | null |
232436fc-4236-42b2-847a-55feeba56ebc | In open angle glaucoma investigation least done is : | Indirect ophthalmoscopy | Tonometry | Direct ophthalmoscopy | Perimetry | 0a | single | Investigations to be done in open angle glaucoma are :
Slit lamp examination
Tonometry
Gonioscopy
Direct ophthalmoscopy
Perimetry | Unknown | null |
0120662c-2bcb-4a25-b0a8-ee3c23603812 | A 50-year-old man with fasting blood glucose >140 mg/ dL on two occasions is put on a restricted caloric diet and started on a glucagon-like peptide-1 (GLP-1) receptor agonist. Which of the following laboratory studies is most likely to afford the best method of monitoring disease control in this man? | Cholesterol, total | Fasting plasma glucose | Glycosylated hemoglobin | Microalbuminuria E Random plasma glucose | 2c | single | Nonenzymatic glycosylation refers to the chemical process whereby glucose attaches to proteins without the aid of enzymes. The degree of glycosylation is proportionate to the level of blood glucose. Many proteins, including hemoglobin, undergo nonenzymatic glycosylation. Because RBCs have a life span of about 120 days,... | Pathology | Endocrine |
46d67568-d256-4e48-a4e1-5d3fff23519a | In case of xeropthalmia secondary to Vitamin A deficiency, what does X2 indicate according to WHO: | Conjunctival xerosis | Bitot's spot | Corneal xerosis | Corneal ulcer | 2c | single | Ans.(c) Corneal xerosisRef: A.K. Khurana 6th ed. /468* Xeropthalmia: all the ocular manifestation of Vitamin A deficiency.* First clinical sign of Vitamin A deficiency: Conjunctival Xerosis* First clinical symptom of vitamin A deficiency: Night blindnessWHO Classification of XeropthalmiaCLASSSIGNSX1AConjunctival xerosi... | Ophthalmology | Symptomatic Conditions |
3d5ecc1e-60c3-4b61-bb87-7824cc7a9af9 | All of the following can result in serotonin syndrome when combined with MAO inhibitors except | Tricyclic antidepressants | Selective serotonin reuptake inhibitors | Carbamazepine | Tyramine containing foods | 3d | multi | Tyramine containing foods along with MAO inhibitors produce cheese reaction that is develop severe hypeension. In serotonin syndrome hypehermia, sweating, restlessness, muscle rigidity, aggressive behavior, tremors, seizures and coma occur. Ref KD Tripati 8th ed. | Pharmacology | Central Nervous system |
82cef1e1-949c-4520-af74-83cfb755e82c | In which type of nerve fibres is conduction blocked maximally by pressure | A alpha | A beta | A gamma | C | 0a | multi | null | Physiology | null |
ff137df2-9c26-4944-a0d7-04688504eedb | According to PALS 2010, all are components of initial impression of child except: | Consciousness | Colour | Airway | Breathing | 2c | multi | Ans: C (Airway) Ref: Pediatric Advanced Life Support 2010 Guidelines. Pediatric Advanced Life Support Provider Manual (A Modification of the Pediatric Assessment Triangle in the 2006 edition of the PALS textbook)Explanation:Consciousness, breathing, colour are seen in initial evaluation. Then Pulse and airway are seen ... | Pediatrics | Newborn Infant - Physical Examination |
9e98f99d-288e-49c4-b1a4-1fb870f0d080 | Dhobi's itch is: | Tinea corfioris | Tinea cruris | Tinea barbae | Tinea capitis | 1b | single | B. i.e. Tinea cruris | Skin | null |
f6839e12-e7c6-45fa-81e5-a200d26c3589 | Endolymphatic sac decompression is done in? | Menieres disease | Otosclerosis | Otitis media | Vestibular schwannoma | 0a | single | Ans. is 'a' i.e., Menieres disease Treatment of Meniere's disease Most treatments are for symptoms believed to be caused by excess endolymphatic fluid. Treatment of Meniere's disease is of two types :? A) Medical management B) Surgical management Medical management: Treatment of Meniere's disease begins first with medi... | ENT | null |
0d4c0885-dac2-4fe9-8b85-eaccced048b0 | CT Scan of head showing a 'Tram track5 appearance in | Neurofibroma | Tuberous sclerosis | Von Hippel Lindau disease | Sturge weber syndrome | 3d | single | Ans. is 'd' i.e.,. Sturge Weber Syndrome. Sturge-Weber syndrome is characterized by -A large unilateral cutaneous angioma* (.Port wine stain*) of the faceA cerebral angioma involving the ipsilateral* cerebral hemisphere and meninges.Adrenal pheochromocytoma*.Cerebral angioma leads to cortical atrophy and epilepsy*.Char... | Radiology | Brain Imaging: Anatomy, Trauma, and Tumors |
aba2d09c-2e6c-4326-ac3c-dd922b0a31ca | Which of the following is not a typical feature of Meniere's disease? | Sensorineural deafness | Pulsatile tinnitus | Vertigo | Fluctuating deafness | 1b | single | null | ENT | null |
0a36ce22-2d2a-41bc-8cbf-1df76c61d9b5 | Salivary gland tumor exclusively seen in parotid gland | Wahin's tumor | Pleomorphic adenoma | Mucoepidermoid Ca | Adenoid cystic Ca | 0a | single | Answer-A. Wahin's tumor"Wahin's tumor arises only in the parotid gland" - Textbook of surgery"Wahin's tumor arises almost exclusively in the parotid gland (the only tumor viually restricted to the parotid)"Salivary gland tumor seen only it parotid gland- Wahins'tumor. | Pathology | null |
38bf209a-e3dc-45bf-8b8b-34a077b815cc | A 60 year old male was diagnosed as carcinoma right lung. CECT of the chest shows a tumor of 5x5 cm in upper lobe and another 2x2 cm size tumor nodule in middle lobe. Which of the following is the treatment of choice? | Surgery | Radiotherapy | Chemotherapy | Suppoive treatment | 0a | single | Question does not indicate the type of lung cancer in the patient. Depending on the given size of the cancer (5cm) and absence of nodal involvement or metastasis, patient is in T2 N0 M0 or Stage I cancer. The current standard of treatment of stage I and II lung cancer is surgical resection, accomplished by lobectomy or... | Surgery | null |
1632e223-d7d1-4cfe-bdd3-ec2910a5cf7b | A most common cause of death due to burns in the early period is? | Sepsis | Hypovolemic shock | Both | None | 1b | multi | Srb's manual of surgery,4th edition Pathophysiology of burns:
1.Burns,
2.Loss of fluid,
3.Severe hypovolemia,
4.Reduced cardiac output,
a.Decreased myocardial function.
b.altered pulmonary resistance causing pulmonary edema,
5.Infection,
6.Systemic inflammatory response syndrome-SIRS,
7.Multiorgan dysfunction sy... | Surgery | null |
42780893-4730-437e-bef5-110d1f541445 | A pregnant patient in second trimester falls into
syncope during extraction of upper molars. She should be kept in | Trendelenburg position | Head down towards her feet | Right Lateral position | Left lateral position | 3d | multi | null | Surgery | null |
3eb0cf99-9b16-4d7a-ad1c-5efbb72ce89b | What is the indication of using Indocyanine green angiography indication in eye? | Occult choroidal neovasularisation | Conjunctivitis | Vitreous hemorrhage | Corneal ulcer | 0a | single | ANSWER: (A) Occult choroidal neovascularizationREF: Vaughan & Asbury's General Ophthalmology 17th ed chapter 2, Kanski 5th Ed Ch 14, Khurana 4th EdPg275INDOCYANINE GREEN ANGIOGRAPHYThe principal use for fluorescein angiography in age-related macular degeneration is in locating subretinal choroidal neovascularization fo... | Ophthalmology | Anatomy |
136e14ef-c905-49dc-b188-a03d206ab47c | Population coverage of primary health center | 20,000 in plain area | 10,000 in tribal area | 30,000 in tribal area | 30,000 in plain area | 3d | single | null | Social & Preventive Medicine | null |
8e2d14c5-3f67-4e60-a1b0-668cc72497ff | Prokaryotes are characterized by - | Absence of nuclear membrane | Presence of microvilli on its surface | Presence of smooth endoplasmic reticulum | All of the above | 0a | multi | Different between Prokaryotes and Eukaryotes PROKARYOTES EUKARYOTES Nuclear membrane absent Nuclear membrane well defined Cytoplasmic structures absent e.g. Mitochondria, Lysosomes, Golgi apparatus, and endoplasmic reticulum are absent. All these cell organelles are present In cell wall muramic acid & diaminopimelic ac... | Microbiology | General Microbiology Pa 1 (History, Microscopy, Stains and Structure and Physiology of Bacteria) |
856c58f9-7564-428b-8c5d-e35ebf73dbdd | Fracture shaft of humerus can cause damage to which of the following nerves? | Median nerve | Ulnar nerve | Axillary nerve | Radial nerve | 3d | single | Radial nerve palsy associated with humeral shaft fractures is the most common nerve lesion complicating fractures of long bones. Radial nerve injury is commonly associated with: Fracture shaft of humerus Saturday night palsy Injection palsy | Surgery | null |
75959259-5a33-4633-998b-80514359b32b | Reliability of screening test does not mean ? | Reproducibility | Repeatability | Validity | Precision | 2c | single | Ans. is 'c' i.e., Validity Repeatability (reliability) Repeatability means, the test must give consistent results when it is repeated more than once on the same individual under same conditions. That means the results of test are precise (exact), So repeatability is some time called precision, reliability or reproducib... | Social & Preventive Medicine | null |
c36a8155-cd28-425a-9af6-b83563e233df | A newborn vomits after each feeding of milk-based formula, and does not gain weight. Biochemical testing reveals a severe deficiency of galactose-1-phosphate uridyltransferase, consistent with homozygosity. If this condition goes untreated, what is the likely outcome for this patient? | Benign disease except for cataract formation | Chronic emphysema appearing in early adulthood | Chronic renal failure appearing in adolescence | Death in infancy | 3d | multi | Galactosemia occurs in two very different clinical forms. Deficiency of galactokinase produces very mild disease with the only significant complication being cataract formation. In contrast, homozygous deficiency of galactose-1-phosphate uridyltransferase produces severe disease culminating in death in infancy. In addi... | Biochemistry | null |
9a46bc3d-6b29-40de-aef8-1db8aca4306d | Structure passing through anterior pa of jugular foramen | Inf petrosal sinus | Internal jugular vein | Internal jugular vein | X, XI nerve | 0a | single | Jugular foramen transmits Through anterior pa: 1. Inferior petrosal sinus 2. Meningeal branch of the ascending pharyngeal aery Notes: through the middle pa: 9th, 10th,11th cranial nerves Through the posterior pa: internal jugular vein and meningeal branch of the occipital aery. BDC 6th edition vol 3 page no:20 | Anatomy | Head and neck |
fcf0e851-e66d-4a42-a5e8-11992065b2c1 | Role of Fluorine in dental health is the following EXCEPT | To make enamel harder than usual | To replace several hydroxyl ions in hydroxyapatite | To make enamel several times less soluble | To promote deposition of calcium phosphate to 'heal' pits in enamel surface | 0a | multi | Ans. a. (To make enamel harder than usual) (Ref. Guyton physiology 11th/994, 879)Role of Fluorine in Preventing Caries. Teeth formed in children who drink water that contains small amounts of fluorine develop enamel that is more resistant to caries than the enamel in children who drink water that does not contain fluor... | Physiology | Misc. |
16c171c8-bf48-43b9-b5ec-b5874aac343d | A 50-year-old family physician has veical diplopia; the man feels unsure when descending stairs. He can eliminate the double vision by tilting his head toward the opposite side. Which of the following extraocular muscles is responsible for the ocular malalignment? | Inferior rectus | Inferior oblique | Lateral rectus | Superior oblique | 3d | single | The superior oblique depresses, abducts, and intos the eye. Paralysis of this muscle results in extorsion and weakness of downward gaze. Head tilting compensates for extorsion. Chin depression would be seen in Superior oblique palsy | Ophthalmology | Squint |
181243ef-f60a-4288-b5bd-a39e33db2c8d | Loss of heterozygosity associated with | Acute myeloid leukemia | ALL | Retinoblastoma | Promyelocytic leukaemia | 2c | multi | Ref Robbins 9/e p292_293 familial case of retinoblastoma 1 defective and 1 normal gene at bih (heterozygous) second mutation causes both genes to be defective loss of heterozygosity Increased chances of cancer sporadic case of retinoblastoma both normal gene at bih _ homogeneous normal genes Both mutations occur somati... | Anatomy | General anatomy |
ec27bb7f-bbc9-4ce5-9a6c-8636f7c2ea6e | JE virus life cycle in nature run between? | Pigs-Mosquito | Cattle-Birds | Pigs-Human | Birds-Pigs | 0a | single | -Japanese encephalitis virus infect several extra human host, animals and birds. - The basic cycles of transmission are from pig to mosquito. Reference : Park's textbook of preventive and social medicine, 23rd edition, pg no:285 <\p> | Social & Preventive Medicine | Communicable diseases |
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