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135
a83b48f3-485f-4afd-b9fd-6bcd8f39f37f
Which of the following enzyme is absent in Wolman's disease?
Cholestrol ester hydrolase
Acid hydrolase
Acyl-CoA carnitine
Acid lipase
3d
single
Ans. D. Acid lipase (Ref. H-17th/ pg. 2454; Table 355-1)WOLMAN'S DISEASE# It is a lysosomal storage disorder, that occurs due to acid lipase deficiency.# Features: increased LDL levels, hypercholesterolemia, atherosclerosis, adrenal calcification and death in infancy itself.Disorders of Neutral LipidsDisorderEnzyme Def...
Biochemistry
Lipids
adae8176-3142-4c7c-9710-45b6e338ab41
Breast is a -
Endocrine gland
Modified sweat gland
Modified sebaceous gland
Holocrine gland
1b
single
Ans. is 'b' i.e., Modified sweat gland o Breast is a modified sweat gland. It is the apocrine type of sweat gland.
Unknown
null
081c1946-d513-40dd-bea2-1e68d16da82a
Which one of the following procedures is most likely to increase intraocular pressure of glaucoma patient –a) Use of atropineb) Decreased pressure in jugular veinc) High dose of vitamin Cd) Dark environmente) Carbonic anhydrase inhibitors.
b
c
ad
ab
2c
single
Any factor which dilates the pupil will precipitate the attack of acute congestive glaucoma. Such factors are dim light (watching a film in a cinema), and mydriatic drugs (atropine, tropicamide, cyclopentolate, phenylephrine). Dilatation of the pupil increases the amount of apposition between iris and anteriorly placed...
Ophthalmology
null
8c4733e6-2128-44e1-a0be-1377fc363a51
Normal serum uric acid levels in males is
3.1 - 7 mg/dl
2.5-5.6 mg/dl
1.2-3.3 mg/dl
1.8-4.4 mg/dl
0a
single
serum uric acid male 3.1-7.0 mg/dL female 2.5-5.6 mg/dL Ref: RAM DAS NAYAK EXAM PREPARATORY MANUAL FOR UNDERGRADUATES 2nd ed. pg no: 784
Pathology
Urinary tract
4b5fc05b-61b1-4b49-9488-e3472c515df7
A female presented with a history of episodes of altered sensorium, involuntary movements, memory deficits and headache since the last 6 months. 4 episodes occurred during the day and 2 during sleep. She has been married since 1 year. Most likely diagnosis is-
Epilepsy
Somatization disorder
Somatoform disorder
Hypochondriasis
0a
single
This patient has Abnormal movements Amnesia (memory deficit) Episode during sleep Amongst the given options, only epilepsy can present with a seizure during sleep. Other three options will not present as a seizure during sleep
Psychiatry
null
d8784495-890d-40b2-999c-14faa877d565
Best investigation for acute intestinal obstruction is:
Barium studies
X-ray
USG
ERCP
1b
single
Diagnosis - X-ray Abdomen: Confirm the clinical suspicion and define more accurately the site of obstruction (60% diagnostic accuracy) Supine radiographs: Dilated loops of small intestine without evidence of colonic distention, diagnose site and level of obstruction. Erect radiographs: Multiple air-fluid levels, which ...
Surgery
Intestinal obstruction
b331ec8c-1497-4ffe-90bf-21616d203bea
GemciGemitis effective in
Head and neck cancers
Pancreatic cancer
Small cell lung cancer
Soft tissue sarcoma
1b
multi
Ref-Katzung 10/891 Gemitabine is an antimetabolite that is the drug of choice for pancreatic cancer
Anatomy
Other topics and Adverse effects
d2791573-0a66-4eb6-bd4f-5d9f110700a0
Features of left side Ca colon are
Anemia
Obstruction
Altered bowel habit
Melena
1b
single
. Patient can have de novo multiple primary carcinomas in different pas of the colon at the same time, i.e. synchronous (5-10%), or can present with growth in different pas of the colon in different periods, i.e. metachronous (10-20%). Gross types: Annular, tubular, ulcerative, cauliflower like. Annular (stenosing) typ...
Surgery
G.I.T
0d972769-edcb-433c-bcd8-0fcb6fdc6a4a
Aphthous ulcers are known as -
Canker sores
Marjolin's ulcer
Curling's ulcer
Cushing ulcers
0a
single
Aphthous ulcers Also known as Canker Sores These are superficial Ulcerations of the oral mucosa. The lesions may be Single or multiple. Ulceration is surrounded by an erythematous halo and is Covered by a thin exudate.
Pathology
null
35a15496-b452-427f-bf18-20d264e26781
All are true regarding brachial plexus injury, except
Preganglionic lesions have a better prognosis than postganglionic lesions
Erb's palsy causes paralysis of the abductors and external rotators of the shoulder
In Klumpke's palsy, Horner's syndrome may be present on the ipsilateral side
Histamine test is useful to differentiate between the preganglionic and postganglionic lesions
0a
multi
Preganglionic lesions have a better prognosis than postganglionic lesions* o Preanlionic Brachial Plexus Injury. o - preganglionic lesions represent root avulsions from the spinal cord o - preganglionic injuries have limited spontaneous recovery; o - surgical repair is impossible (bad pregnosis as compared to post-gang...
Surgery
null
0403d72c-ddc2-41a5-949e-258ee984157e
Ligamentum teres is remnant of -
Umbilical arteries
Left umbilical vein
Ductus-venosus
Ductus arteriosus
1b
single
Ans. is 'b' i.e., Left umbilical vein o The ligament teres represents the obliterated left umbilical vein.Embryonic partRemnantsDuctus arteriosusLigamentum arteriosumUmbilical arteryProximal partSuperior vesical artery.Distal partMedial umbilical ligamentUmbilical veinLigament teresDuctus venosusLigamentum venosusSeptu...
Anatomy
Embryology
026d9d88-1115-4b30-b7a2-cd3651809482
Interstitial nephritis is most commonly seen with -
Methicillin
Ampicillin
Amoxycillin
Cloxacillin
0a
single
Ans. is 'a' i.e., Methicillin o Hematuria, Albuminuria and reversible interstitial nephritis are the specific adverse effect of methicillin. Remember o Methicillin - Intestitial nephritis o Oxacillin - Hepatitis o Nafcillin - Neutropenia o Ampicillin - Diarrhea
Pharmacology
null
7a0d18a7-433d-445f-b68e-695b79afe3cd
Malignant neuroleptic syndrome is caused by:March 2009
Antidepressants
Anxiolytics
Antipsychotics
Antiepileptics
2c
single
Ans. C: AntipsychoticsNeuroleptic malignant syndrome (NMS) refers to the combination of hypehermia, rigidity, and autonomic dysregulation that can occur as a serious complication of the use of antipsychotic drugs.The list of atypical antipsychotic drugs that may cause NMS include olanzapine, risperidone, paliperidone, ...
Psychiatry
null
d432ca2c-435b-4c07-b5a6-3d687ad04c28
Feathery appearance in jejunum is due to –
Valvulae conniventes
Haustrations
Luminal gas
Vascular network
0a
single
The nervous and villous coat of the jejunum are extensive and are thrown into folds, called Valvulae conniventes which give feathery appearance in the jejunum.
Radiology
null
781195f7-fa9b-462a-9db1-1de4f7763f96
Daily release of ho rmonefrom mirena is -
10 microgram
20 microgram
30 microgram
40 microgram
1b
single
Ans. is 'b' i.e., 20 microgram Mirena:o It is levennogesterol releasing intrauterine contraceptive device system.o It measures about 32 x 32 mm.o It has a life span of 5 yearso It contains 52 mg of levenogesterol.o It releases 20 meg/ day of levenogesterol.
Gynaecology & Obstetrics
Methods - Progestogen-Only Contraception
eee23968-1660-44ba-9d12-397a2a62cdbf
In the early stage of which of the following carcinoma, no lymphatics involved:
Glottic CA
Infraglottic CA
Supraglottic CA
Hypopharyngeal CA
0a
single
Ans. (a) Glottic CARef: Dhingra's ENT 5th ed. / 327* Most common laryngeal malignancies are squamous cell CA (90-95%).* It can be any of these three sites:Supraglottis2nd MC site. Nodal metastasis occur early. MC to middle jugular nodes Symptom: Throat pain, Dysphagia, referred pain to ear > HoarsenessGlottisMC site. L...
ENT
Tomour of Larynx
da395a79-51b9-4408-9f11-69475bc27085
All the following are true about Upper End Of Tibia EXCEPT:
Ossification centre for the upper end fuses by 18 years
Meniscal Cailage is attached to the Intercondylar Area
Gives attachment to Semimembranosus
Posterior aspect of Patella aiculates with Upper End Of Tibia laterally
3d
multi
Patella has no aiculation with Tibia; it is aiculated to Femur Only. Ossification: Secondary Centre for the Upper End is present at bih and fuses with the shaft by 16 years in females and 18 in males. Both Medial and Lateral menisci are attached to the Intercondylar Area on tibia. Semi-membranosus muscle is attached to...
Anatomy
Bones Joints and Ligaments
60df544e-e82b-47d0-bd8b-fca35fc7cd51
Hyperkalemia shows the following changes in ECG, except
Increased T wave amplitude
Prolonged PR interval
ST depression
Prolonged QRS duration
2c
multi
null
Medicine
null
99259615-1192-4a5c-bacc-0a4a3ea31184
Drug of choice among these for neonatal seizures:
Phenobarbitone
Phenytoin
Diazepam
Clobazam
0a
single
Ans. A. PhenobarbitoneThe drug of choice for treating neonatal seizures is phenobarbitone. Its initial IV dose is 20-40mg/kg IV, followed by maintenance dose of 3-5mg/kg/dayIV/IM or oral.
Pediatrics
Central Nervous System
2813d9d4-bf61-48e1-8058-9bbcc3c322eb
Tennis elbow is
Inflammation of lateral epicondyle of humerus
Inflammation of medial epicondyle of humerus
Avulsion injury of head of radius
Avulsion injury of olecranon process
0a
single
Tennis elbow is a condition characterised by pain and tenderness at the lateral epicondyle of the humerus due to non-specific inflammation at the origin of the extensor muscles of the forearm.Maheswari 5th edition Pg: 302
Orthopaedics
Elbow injuries
5bef725d-7c7a-4987-ab0a-5b300b501f40
M/C type of breech presentation:
Frank breech
Complete breech
Footling
Knee
0a
single
Ans is a, i.e. Frank breechRef Fernando Arias 4/e, p 375Varieties of breech:CompleteIncomplete:-Frank breech (70%)-Footling breech-Knee breech
Gynaecology & Obstetrics
Malpresentation
104ef788-edc8-45e0-8ef2-a2ad76c38e27
Presumptive count includes
No E. Coli
Coliform but not only E.
Gram negative bacilli
Any bacteria
1b
single
Presumptive coliform test In presumptive coliform test the most probable number of all coliform organisms (not only E.coh) are counted → Presumptive coliform count. The methods are : - Multiple tube method Membrane filtration technique. After analysing presumptive coliforrn count, E.coli count is confirmed by othe...
Social & Preventive Medicine
null
2c812472-e452-4cba-a0fa-fc178f9148a2
Killian's dehiscence is seen in:
Oropharynx
Nasopharynx
Cricopharynx
Vocal cords
2c
single
Ans. c (Cricopharynx). (Ref. Diseases of ENT by PL Dhingra, 3rd /pg. 290)# Inferior constrictor muscle has two parts:- Thyropharyngeus (oblique fibers)- Cricopharyngeus (transverse fibers)# Between these two parts exists a potential gap, known as "Killan's dehiscence" (gateway of tears).# Clinical significance:- Perfor...
ENT
Pharynx
b04d724e-c87b-4261-ba68-bec6f30d227e
Type of graft, best suited for renal transplantation -
Allograft
Autograft
Xenograft
Isograft
3d
multi
Although the best graft is-autograft, a renal graft can obviously not be an autograft. So the best renal graft is an isograft.
Microbiology
null
930d7d7d-187f-43bc-b01d-97ea65599e6e
True about Gilbe syndrome is:
Conjugated hyperbilirubinemia
Starvation improves the condition
Phenobarbitone improves the condition
Life-threatening
2c
multi
Gilbe syndrome: Unconjugated hyperbilirubinemia Paial deficiency of UDPglucuronyl transferase enzyme Jaundice precipitated by fasting Phenobarbitone, being an enzyme inducer, improves the condition by increasing the activity of UDP glucuronyl transferase enzyme
Pediatrics
Liver disorders
ed26feee-795c-41d7-85dc-26b36c6c3e02
'Tiger eye' appearance on MRI brain is characteristic feature of:
Refsum's disease
Hallervorden Spatz disease
NARP mitochondrial disease
Abetalipoproteinemia
1b
multi
Ans. B. Hallervorden Spatz diseaseHallervorden- Spatz Disease (are neurodegenerative disorder of basal ganglia)DefinitionHallervorden- Spatz disease (HSD) is a rare disorder characterized by progressive extrapyramidal dysfunction and dementia. It's an iron metabolic disorder.Genetics1. The disease can be familial or sp...
Radiology
Nervous System
c42c9f8c-5dc1-4fb1-8a13-9d0d7fc05e75
Most of the CO2 transported in the blood is
Dissolved in plasma.
In carbamino compounds formed from plasma proteins.
In carbamino compounds formed from hemoglobin.
In HCO3–
3d
single
The CO2 that diffuses into red blood cells is rapidly hydrated to H2CO3 because of the presence of carbonic anhydrase. The H2CO3 dissociates to H+ and HCO3-, and the H+ is buffered, primarily by hemoglobin, while the HCO3- enters the plasma.
Physiology
null
f929aff2-b8c2-44f7-aebe-c02459ae88e5
Crypta Magna is the remnant of
First Pharyngeal pouch
Second Pharyngeal pouch
Third pharyngeal pouch
Fouh pharyngeal pouch
1b
single
Medial surface of each tonsil has 15-20 crypts, the largest of which is called Intratonsillar cleft or crypta Magna (which represents the persistence of the ventral poion of the second pharyngeal pouch)'.Ref: PL Dhingra, Diseases of Ear, Nose & Throat, 7th edition, pg no. 291
ENT
Oral cavity & Oesophagus
ab5ef317-80a2-40dd-a936-e090da751d25
Which is the true statement regarding megaloblasitc anemia-a) Megaloblastic precursors are present in bone marrowb) Mean corpuscular volume is increasedc) Serum LDH is increasedd) Thrombocytosis occurse) Target cells are found
ab
bc
abc
bcd
2c
multi
null
Pathology
null
f6dc814c-4c1e-445a-a238-6eff973434ca
A 30 year old primipara in labor with transverse lie treatment of choice is
Internal cephalic version
Emergency cesarean section
Wait and watch
External cephalic version
1b
single
Patients in labor with transverse lie can be managed by external cephalic version followed by surgical rupture of membrane But it is impoant to note that the patient is primigravuda with age 30years i.e, elderly primi so ECV is contraindicated This patient requires emergency cesaream section
Anatomy
Abnormal labor
90dbca2f-c7e0-4e31-8a44-fd0887d62eee
The early feature of Pott's paraplegia is -
Flexor spasm
Increased tendon jerk
Ankle clonus
Sensory loss
2c
single
Potts Paraplegia * It is a most serious complication of spinal TB,incidence is appr 20%. * MC in dorsal spine because it is the narrowest region,abcess remains confined under tension and even a small compromise can lead to neurological deficit,infection is common in this area and spinal cord terminates below L1 * Early...
Orthopaedics
Skeletal infections
73e99d3b-c06f-4d02-99e6-ee5ad7275a99
Winter bottoms sign in sleeping sickness refers to -
Unilateral conjunctivitis
Posterior cervical lymphadenopathy
Narcolepsy
Transient erythema
1b
single
Generalized or regional lymphadenopathy - Posterior cervical lymphadenopathy (Winterbottom sign) is characteristic of T brucei gambiense African trypanosomiasis
Microbiology
parasitology
7424abce-b85b-42e5-83d1-2d0741b6b98f
Compared with cow's milk, mother's milk has more -
Lactose
Vitamin D
Proteins
Fat
0a
single
Lactose content in cows milk-4.4g ,breast milk-7.4g per 100grams.REF.PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE.Editon-21.Page no.-582 table 21
Social & Preventive Medicine
obstetrics,pediatrics and geriatrics
46950810-7b8b-4048-be41-9026c2067c9d
C/F of Turner&;s syndrome:
Secondary amenorrhea
Edema of hands and feet
XY genotype
Mental retardation common
1b
single
Turner's syndrome 45,XO genotype sho strature neck is sho and webbed shield chest,high palate,low set ears lymphoedema of extremities at bih SHAW'S TEXTBOOK OF GYNAECOLOGY,Pg no:111,15th edition
Gynaecology & Obstetrics
Sexuality and intersexuality
91490220-f450-425a-b08b-cb5afb14084e
Strength of sewage is expressed in terms of all EXCEPT:
Biological Oxygen Demand
Chemical oxygen demand
Suspended solids
Coliform count
3d
multi
Ans. d (Coliform count). (Ref. Park PSM 22nd/pg. 708)SEWAGE# It is wastewater from community containing solid and liquid excreta, derived from houses, street and yard washing, factories and industries.# It resembles dirt water with unpleasant smell.# Composition of sewage is 99.9% water.# Average adult person excretes ...
Social & Preventive Medicine
Environment and Health
2c83bc82-0c12-48ae-84e7-3970674ff131
A bilipid layer is most permeable to -
Potassium
Sodium
Glucose
Urea
3d
single
Ans-DThe lipid bilayer is impermeable to most water-soluble molecules.Lipid soluble molecules readily enter the cellsMolecules that move rapidly through a given membrane (lipid bilayer) are said to have a high Permeabilitycoefficient: - as followsFig.: Permeability coefficients of water, some ions, and other small mole...
Unknown
null
6eef55c2-ff1c-4252-9c39-368d9df36121
Essential amino acid amongst the following -
Valine
Lysine
Threonine
All
3d
multi
Ans. is 4d' i.e.. All Nutritionally Essential Nutritionally Nonessentiai Arginine - semi essential Alanine Histidine Asparagine Isoleucine Asparatate Leucine Cysteine Lysine Glutamate Methionine Glutamine Phenylalanine Glycine Threonine Praline Tryptophan Serine Valine Tyrosine
Unknown
null
3482a501-d805-4aeb-93d0-510bb55480b8
The following set of words can be used synonymously in epidemiology -
Source and Reservoir
Index and primary case
Latent infection and subclinical infection
Serial interval and incubation period
2c
single
Ans. is 'c' i.e., Latent infection and subclinical infection Though none of the given pairs can be used as synonymously, the best answer is 'c'.
Social & Preventive Medicine
null
0c05e387-5c3a-4b0a-a003-bee1db15d1d8
A patient presents with bilateral proptosis, heat intolerance and palpitations. Most unlikely diagnosis here would be
Hashismoto's thyropidittis
Thyroid adenoma
Diffuse thyroid goitre
Reidel,s thyroiditis
3d
single
null
Surgery
null
29e28b81-8db2-455f-b075-21608e3db798
Iron is maximum in
Pista
Cashewnut
Meat
Milk
2c
single
Ans. is 'c' i.e., Meat
Social & Preventive Medicine
null
ed6737ed-1626-4680-b8d8-c66e8cc6907b
CSF rhinorrhea can be seen in:
Lefort 2 fracture.
Lefort 3 fracture.
Nasoethmoidal fracture.
All of the above.
3d
multi
null
Surgery
null
5e79f9b6-31f1-426d-895d-c32f6e18d19c
Surgery for mitral stenosis during pregnancy is ideally done at :
14 weeks
20 weeks
28 weeks
32 weeks
0a
multi
14 weeks
Gynaecology & Obstetrics
null
b6dd0ee8-9fa1-4664-bb09-496c00aa2c65
Following statements are true regarding first pharyngeal arch :
Maxillary & mandibular prominences are formed
Maxilla & Zygomatic bone are formed by intermembranous ossification
Tensor palati formed by first arch
All
3d
multi
A i.e. Maxillary & mandibular prominences are formed; B i.e. Maxilla & Zygomatic bone are formed by intermembranous ossification; C i.e. Tensor palati formed by first arch
Anatomy
null
4c3587ae-04e4-4f29-b02f-2ecf5de8d0b6
all are ture ragrding gall stones management except ?
it should be cholestrol stone
it should be radio opaque
function gallbladder
non acute symptoms
1b
multi
medical management of gallstones : it should be cholesterol stone it should be radioluscent gallbladder should be functioning non acute symptoms size of stone <1.5cm ref : bailey and love 27th ed
Surgery
All India exam
6d326b8d-e98a-4b85-824a-3d0dc338477d
58-year-old man suffered road traffic accident and came to the hospital. He had multiple fractures in his lower limbs, ribs and lung contusion. Ultimately he succumbed to his injuries. At autopsy, a biopsy from the lung showed the following appearance. What is the likely cause of his death?
Fat embolism
Emphysema
Pulmonary embolism
Congestive hea failure
0a
single
Indeed, fat embolism occurs in some 90% of individuals with severe skeletal injuries Fat embolism syndrome Term applied to the minority of patients who become symptomatic. It is characterized by:- Pulmonary insufficiency, Neurologic symptoms, Anemia, and Thrombocytopenia, Staining:- Because lipids are dissolved out of ...
Pathology
Systemic Pathology
42524ed0-0f34-45fa-9e1d-26cfec81c266
Liver synthesizes all, except:
C3 complement component
Hap Toglobin
Fibrinogen
Immunoglobulin
3d
multi
D i.e. ImmunoglobulinAlpha (a ) and beta (f3) globulins are produced by hepatocytes (liver), where as immunoglobins or gamma globins are produced by B- lymphocyte (plasma cell)Q.Proteins synthesized by liver areProteinFunctionAlbuminOrmotic regulator; and carrier protein binding hormone, aminoacids,sterioids, vitamins,...
Physiology
null
5b6d90e8-4cf6-4fb4-b5c8-2c96d1dc4db1
Which of the following excludes painful stimuli from awareness:
Repression
Reaction formation
Projection
Rationalization
0a
single
A i.e. Repression Defence mechanism Definition Normal example Pathological example Repression - It is (unconscious or conscious) exclusion, expulsion - Forgetting; eg painful - Psychogenic or withholding of an unaccepted anxiety, pain or aspects of memory of amnesia distress provoking sturnuli (idea, impulse, emotion, ...
Psychiatry
null
ee2d1dab-c3d5-4d8c-a168-5c79974db0d6
The rate-limiting step in the biosynthesis of catecholamines is catalyzed by
Tyrosine hydroxylase
Dopa decarboxylase
Dopa mine f3 hydroxylase
Catechol-O-methyltransferase
0a
multi
The rate limiting step in the synthesis of catecholamines is catalysed by tyrosine hydroxylase Ref : guyton and hall textbook of medical physiology 12 edition page number:605,606,607
Physiology
Nervous system
48ca7f3b-1197-4614-8b1a-4a5ef7d3f6b6
A 25 year old male gives history of sudden painless loss of vision in one eye for the past 2 weeks. There is no history of trauma. On examination the anterior segment is normal but there is no fundal glow. Which one of the following is the most likely cause?
Vitreous haemorrhage
Optic atrophy
Developmental cataract
Acute attack of angle closure glaucoma
0a
single
Ans. (a) Vitreous hemorrhageRef: Kanski 7/e, p. 730Sudden painless loss of vision with absence of fundal glow and a normal anterior chamber, in absence of trauma (spontaneous) is consistent with a diagnosis of spontaneous vitreous hemorrhage.Vitreous hemorrhageSudden painless loss of visionOptic atrophyGradual painless...
Ophthalmology
Retina
187797ac-19f4-4c6d-9419-7d894c8fd4d6
Screening for condition recommended wrhen -
Low case fatality rate
Diagnostic tools not available
No effective treatment available
Early diagnosis can change disease course because of effective treatment
3d
single
Ans. is 'd' i.e., Early diagnosis can change disease course because of effective treatment o The disease to be screened should fulfil the following criteria before it is considered suitable for screening.1. The condition sougth should be an important health problem (in general, prevalence should be high).2. There shoul...
Social & Preventive Medicine
Screening for Disease
6bab5937-5032-4e0f-a4c6-8644b512d399
Parathyroid hormone is responsible for all actions except:
Absorption of phosphorous increase
Vit D absorption increases
Mobilizes calcium from bone
Increase intestinal absorption of calcium
0a
multi
A i.e. Absorption of phosphorus increaseParathyroid hormone increases phosphate excretion in urine due to decrease in reabsorption of phosphate in the proximal tubulesQ.
Physiology
null
1aa2ec95-8b25-4b5e-aa51-e3789b9bdcc6
In which of the following disease, the overall survival is increased by screening procedure -
Prostate Ca
Lung Cancer
Colon Ca
Ovarian Ca
2c
multi
.there is strong positive correlation between cancer colon and dietary fat.the studies have shown that increase in the dietary intake of fat has recently increased the incidence of ca colon in the western communities like japan.also dietary fibre intake is said to have a protective role in the development of carcinoma ...
Social & Preventive Medicine
Screening
6646de41-8d52-43b0-b2aa-41ef2e847024
Diuretic used in mountain sickness?
Hydrochohiazide
Furesemide
Acetazolamide
Spironolactone
2c
single
ACTIONS OF ACETAZOLAMIDE: i) Lowering of intraocular tension due to decreased formation of aqueous humor (it is rich in HC03). 2) Raised level of C02 in the brain and lowering of pH - sedation and elevation of seizure threshold. 3) Alteration of C02 transpo in lungs and tissues: - used in high altitude or mountain sick...
Pharmacology
Kidney
a91b4760-1cb4-4c4d-a83e-e5c6cc5cdcd2
In treatment of Parkinsonism with Levodopa dose limiting toxicity is
Choriform movements
Vomitings
Tardive dyskinesia
Giddiness
1b
single
(B) Vomitings # ADVERSE EFFECTS 2# HAEMATOLOGICAL Dose limiting toxicity> Leucopenia, nadir 21 - 28 days, recovery 28 - 35 days.> Thrombocytopenia, nadir 16 days, recovery 21 days.# GASTROINTESTINAL Dose limiting toxicity> Severe nausea and vomiting, duration 1-12 hours. Aggressive antiemetic prophylaxis is recommended...
Medicine
Miscellaneous
f419e5f8-ffaf-496e-b323-4f8de29fa129
The first sign of tetanus is
Dysphagia
Neck stiffness
Back pain
Trismus
3d
single
null
Medicine
null
a7e4d76d-bd99-45b2-b173-cd05d4fac860
Hanging in which body is fully suspended and feet are not touching the ground?
Paial hanging
Complete hanging
Homicidal hanging
Suicidal hanging
1b
single
HANGING ON THE BASIS OF SUSPENSION Hanging in which body is fully suspended and feet are not touching the ground is called complete hanging. Hanging in which feet or pa of body touches the ground and the body is not fully suspended is called paial hanging.
Forensic Medicine
Hanging and strangulation
ccf1bb2c-a1df-4531-a030-2a936bccb32a
Hysteroscopy is used in all EXCEPT :
Uterine synechiae
Abnormal vaginal bleeding
Infeility
None
3d
multi
None
Gynaecology & Obstetrics
null
f79105fa-3a81-4c66-a242-e1311e953d62
Tryptophan is glucogenic & ketogenic by producing
Acetyl CoA & alanine
Acetoacetate & fumarate
Acetoacetate & arginine
Arginine & alanine
0a
single
The major metabolic fate of tryptophan is to be oxidized by tryptophan pyrrolase (tryptophan di-oxygenase) (Step 1, Fig. 17.8). It is a hemoprotein. The enzyme is inducible by coicosteroids.iii. In this major pathway, the total 11 carbon atoms of tryptophan are catabolized as formyl group (1C which enters the one-carbo...
Biochemistry
vitamins
3cd72c66-ff0a-4e5c-9b9b-95be24dfd293
In Holmes-Adie pupil all are true except -
There is absent or retarded pupil reactions to light and near
Most cases are bilateral
Causes reduced or absent accommodation
Constricts with 2.5% methacholine
1b
multi
The Adie's tonic pupil. In this condition reaction to light is absent and to near reflex is very slow and tonic. The affected pupil is larger (anisocoria). Its exact cause is not known. It is usually unilateral, associated with absent knee jerk and occurs more often in young women. Adie's pupil constricts with weak pil...
Ophthalmology
Neuro-ophthalmology
c60f2e5a-61b0-4499-a30d-63dafb4fde9d
Pitting edema indicates an excess of .... litres of fluid in tissue spaces -
2.5
3.5
4.5
5.5
2c
single
null
Surgery
null
3d14c2a0-cf0f-42dd-979a-20a5c2058b9f
Which of the following does not pass through cavernous sinus?
Occulomotor (III) nerve
Trochlear nerve
Medial cerebral artery
Trigeminal nerve
2c
single
null
Anatomy
null
96ce8e3c-aea0-4481-ac52-db9cb435abbf
Mistuda reaction is read at
21st day
10th day
3rd day
45th day
0a
single
null
Social & Preventive Medicine
null
6ef5ff5d-49f3-4533-a7a5-b4a2f8f04d26
True regarding IgA nephropathy is
Usually seen in children <10 years of age
Microscopic hematuria is common presentation
Recurrent gross hematuria following respiratory infections
Decreased serum IgA
2c
multi
IgA nephropathy, characterized by mesangial deposits of IgA-containing immune complexes, is the most common cause of the nephritic syndrome worldwide; it is also a common cause of recurrent hematuria; it commonly affects children and young adults and has a variable course. Ref: Robbins basic book of pathology 9th editi...
Pathology
Urinary tract
e30d3f56-49f7-4bf4-a5f6-cc42166ff86a
Donovan bodies are seen in:
Granuloma inguinale
LGV
Syphilis
Herpes genitalia4
0a
single
Ans. is 'a' i.e., Granuloma inguinale
Skin
null
4360d1c0-89a1-48a2-9bf6-e9c99036d492
Which of the following nerve innervates rhomboids minor muscle?
Medial pectoral nerve
Long thoracic nerve
Dorsal scapular nerve
Nerve to the subclavius
2c
single
Dorsal scapular nerve innervates the rhomboids minor muscle which is involved in retraction of the scapula. Medial pectoral nerve innervates pectoralis minor which is involved in protraction, depression, and stabilization of scapula.Long thoracic nerve innervates serratus anterior which is involved in protraction and r...
Anatomy
null
80252a64-26ce-4225-92ac-47f0de4d3142
Example of neuromuscular blocker causing hypotension is:
Rocuronium
Vecuronium
Pancuronium
Atracurium
3d
single
The hypotension seen with the use of atracurium and mivacurium is due to release of histamine, whereas dTubocuranine causes hypotension histamine release and ganglion blockade. Ref: Miller's anesthesia-7th ed, Chapter 29.
Anaesthesia
null
8d26a97d-fde3-410e-b85b-48e4e6518c84
Anthrol acts as purgative due to -
Irritant action
Bulk formation in intestinal lumen
Osmotic action
Emollient effect
0a
single
Ans. is 'a' i.e., Irritant action o Anthroquinones (senna, cascara sagrada) are stimulant purgatives --> irritate the intestinal mucosa and thus stimulate motor activity.
Pharmacology
null
70a23529-fe33-4dd8-999a-bf70b4084332
Which of the following sexually transmitted disease is diagnosed by Ito's test?
Gonorrhoea
Herpes
Chancroid
Granuloma venereum
2c
multi
The Ito-Reenstierna test is an intradermal test, using inactivated Haemophilus ducreyi, for diagnosis of chancroid. Due to limited sensitivities for detection of circulating antibodies to H. ducreyi, serology has currently limited usefulness in the routine diagnosis of chancroid infection but may be useful in populatio...
Microbiology
null
2a7a4c60-ade9-4129-bef1-3b78f40f25b5
Which of the following finding is not suggestive of intrinsic hepatic fibrosis:
Bulging flanks
Collateral flow toward umbilicus
Eveed umbilicus
Venous hum
1b
single
In caput medusa the blood flows away from the umbilicus and is suggestive of poal hypeension. The increased flow results in a venous hum. The abdominal distention due to ascites explains flank fullness and eveed umbilicus.
Medicine
Misc.
f71b0459-5bbe-468b-8efd-fbd457d5c1c8
Omega shaped epiglottis is seen in?
Laryngomalacia
Epiglottitis
Tuberculosis
Carcinoma of epiglottis
0a
single
ANSWER: (A) LaryngomaiaciaREF: Dhingra 4th ed p.272In laryngomaiacia direct laryngoscopy shows elongated epiglottis, curled upon itself (omegashaped), floppy aryepiglottic folds and prominent arytenoids.Pediatric Epiglottis is omega-shaped and arytenoids relatively large covering significant portion of the posterior gl...
ENT
Larynx
5bde04b4-a48c-40de-aa3d-2e3020c14829
Common injury to baby is -
Fracture humerus
Fracture clavicle
Fracture scapula
Fracture femur
1b
single
The most common bone to be fractured in children and during birth is clavicle.
Orthopaedics
null
08467e2a-95da-4a74-887c-2289fffc8c59
Contact dermatitis is -
Type-I hypersensitivity
Type-II hypersensitivity
Type-III hypersensitivity
Type-IV hypersensitivity
3d
single
Contact dermatitis is a type IV hypersensitivity reaction. - delayed hypersensitivity sometimes results results from skin contact with a variety of chemicals - metals such as nickel and chromium, simple chemicals like dyes,drugs or plant allergens. The antigen activates specifically sensitised CD4 & CD8 T lymphocytes l...
Microbiology
Immunology
9aff3318-c2e2-416e-b131-72d1529bbafb
Gamma amino butyrate is synthesized from? -
Fumarate
Glutamate
Histidine
Glycine
1b
single
Ans. is 'b' i.e., Glutamate \Ref: Harper 29th/ e p. 304-305]o Gamma amino butyric acid (GABA) is formed by decarboxylation of L-glutamate.Amino acidsBiological important compoundTyrosineCatecholamines (epinephrineQ, norepinephrineQ, dopamineQ), thyroxineQ, triiodothryonine, melanin Q.(Note: - Phenylalanine is the precu...
Biochemistry
Amino Acids Basics
b6deed39-8b87-4f63-af3d-3cab936ce08e
Caloric requirement of adult male worker with moderate levels of activity is:-
2320 Kcal /day
2230 Kcal /day
2730 Kcal/day
3490 kcal/day
2c
single
Caloric requirement of Adult Male worker:- Sedentery levels of activity - 2320 Kcal/day Moderate levels of activity - 2730 Kcal/day Heavy levles of activity - 3490 Kcal/day. Caloric requirement of Adult Female worker:- Sedentery levels of activity - 1900 Kcal/day Moderate levels of activity - 2230 Kcal/day Heavy levles...
Social & Preventive Medicine
RDA, Nutritional Requirements
50d7e929-69bc-4731-9d94-b3fca1852ecc
Which of the following is associated with adult polycystic kidney disease?
Berry aneurysms in Circle of Willis
Saccular aneurysms of aorta
Fusiform aneurysms of aorta
Leutic aneurysms
0a
single
Ans. is 'a' i.e. Berry Aneurysm in Circle of Willis Extrarenal anomalies seen in patients with adult polycystic kidney disease.||||CystsBerry aneurysmColonic diverticula*Mitral valve(a) Liver (M.C. Site)*(Present in 5-10%)(M C. extrarenal deformity )Prolapse*(b) Spleen* perforation is common (c) Pancreas* (d) Ovaries
Pathology
Miscellaneous (Kidney)
276670bc-dc92-4f3e-9c9d-242922e3abc0
Contraindications to major hepatic resection for metastatic disease include all of the following Except
Total hepatic involvement
Advanced cirrhosis
Extrahepatic tumor involvement
Jaundice from extrinsic ductal obstruction
3d
multi
HEPATIC RESECTION Indications * Parasitic and non-parasitic cysts. * Benign and primary malignant tumours of the liver. * A secondary tumour that involves by direct extensions like from carcinoma of the gallbladder or limited secondaries from carcinoma colon/carcinoids. * Trauma to the liver. Contraindication * Advance...
Surgery
G.I.T
7a1584e4-5978-450a-9a23-8df97df816fc
Muscle that causes flexion at elbow joint when forearm is semi - pronated
Biceps brachii
Brachialis
Coracobrachialis
Brachioradialis
3d
single
Brachioradialis causes flexion at elbow joint when forearm is semi - pronated.
Anatomy
null
0ad006c2-aaa6-4f46-af8d-b9d18f5549bb
Spermatogenesis begins at -
Birth
5 years
Puberty
18 years
2c
single
Ans. is 'c' i.e., Puberty o Spermatogenesis refers to the process of formation of spermatozoa (sperm) from primitive germ cells (spermatogonia).o Spermatogenesis begins at puberty and continues throughout adult life to decline in old age.o In humans, it takes an average of 74 days to form a mature sperm from primitive ...
Anatomy
Fertilization and Development of Embryo
3bd7b023-4cb2-408d-a87f-f3ce9833ce13
Which of the following drug is used for Lithium induced tremors?
Add valproate
Propranolol
Trihexyphenidyl
Tetrabenazine
1b
single
Ans. B. PropranololNeurological Effects of lithium1. Tremor: postural tremor (8to12Hz) (treatment- b-Adrenergic receptor antagonists, such as propranolol)2. Cognitive Effects (dysphoria, lack of spontaneity, slowed reaction times and impaired memory)3. Other Neurological Effects: symptoms of mild parkinsonism, ataxia, ...
Psychiatry
Pharmacotherapy In Psychiatry
77fc199f-9595-423c-bcda-bd90f784599b
Extraocular muscle not supplied by oculomotor: (D. REPEAT 2011)
Superior oblique
Super rectus
Medial rectus
Inferior oblique
0a
single
Ref: Basaks Essentials of Ophthalmology, 5th edition Explanation:EXTRAOCULAR MUSCLESTotal 6 muscles (4 Rectus and 2 Oblique muscles).Rectus musclesOrigin: Common origin from annular tendon of Zinn around the optic foramen at the apex of the orbit.Insertion: They are inserted to the sclera after piercing the Tenon's cap...
Ophthalmology
Ocular Motility
00c1dd5b-96c6-4cda-a43c-ad3790a49a5a
Casoni's test is positive in
Echinococcus
Enterobius
Taenia solium
Taenia saginata
0a
single
Ans. a (Echinococcus)TestUsed forAdrenolytic testPheochromocytomaAllen testIn patients with severe Raynaud's phenomenon and refractory digital ulcers due to distal ulnar artery occlusion.Anticholinesterase testMyasthenia gravisApnea testDemonstration that apnea is due to irreversible medullary damage.Bentiromide testis...
Microbiology
Parasitology
11e07dff-2940-4e37-a1f6-361bd427b5b1
In comparison to breast milk, colostrum has a higher content of
Carbohydrates
Fat soluble vitamins
Water
Potassium
1b
single
Colostrum is the milk secreted during the first three days. It is yellow, thick and contains more of antibodies and fat-soluble vitamins.Transitional milk is that secreted during the following 2 weeks and contains plenty of immunoglobulins.This is followed by mature milk which is thin and watery.(refer to pgno: 430 She...
Gynaecology & Obstetrics
General obstetrics
fce0a6db-309c-46db-bd13-3550ab71486f
Drugs within the following groups react unourably with lithium
ACE inhibitors
Morphine
Valproate
Antipsychotics
0a
single
Causes worsening of lithium toxicity and renal damage
Pharmacology
All India exam
8111f865-90ee-4734-995e-2cf697be7756
"Periglomerular" Fibrosis is considered typical of:
Chronic pylonephritis
Chronic glomerulonephritis
Aerionephrosclerosis
Malignant hypeension
0a
single
Chronic pylonephritis
Pathology
null
2315fbec-c20b-4ed7-a1c2-7d351bbedafe
Which of the following can be ophthalmic complication of DM except -
Papillopathy
Snowflake cataract
Retinopathy
Rhegmatogenous retinal detachment
3d
multi
Answer- D. Rhegmatogenous retinal detachmentOcular manifestations of diabetic retinopathy are-1) Non- proliferative diabetic retinopathy (NPDR)-MicroaneurysmsRetinal hemorrhageRetinal edema (Retinal thickening)- macular edema.2) Proliferative diabetic retinopathy (PDR)Hallmark of PDR is the occurance of neovascularizat...
Ophthalmology
null
f8dfd273-2779-4e7e-95db-97b24f14189a
In the entire human genome, coding DNA constitutes?
2%
1%
0.10%
4%
0a
single
Ans. a. 2%
Physiology
null
c930d295-dd3a-4012-81c2-e02e452546f0
Natural disasters are all except -
Floods
Tomedo
Lightening strike
Accidental radioactive gas leak from factory
3d
multi
Ans. is 'd' i.e., Accidental radioactive gas leak from factory o A natural disaster is a major adverse event resulting from natural processes of the Earth; examples include floods, volcanic eruptions, earthquakes, tsunamis, and other geologic processes,o Accidental radioactive gas leak from factory is most commonly a r...
Forensic Medicine
Misc.
0874a338-5de1-4c89-ba01-a6fe05ef1242
DOC for "rapid cyclers" type of bipolar disorder is-
Carbamazepine
Valproate
Phenytoin
Lithium
1b
single
null
Psychiatry
null
74c0292e-a07f-41ed-8cde-966664aae7ca
Surgery is not useful in
Cerebral oedema
Depressed fracture
Extral dural haemorrhage
Subdural haemorrhage
0a
single
null
Surgery
null
208d34d4-744b-423c-a4b5-d001bf14fbde
A 40 year old man has chronic cough with fever for several months. The chest radiograph reveals a diffuse reticulondular pattern. Microscopically on transbronchial biopsy there are focal areas of inflammation containing epitheloid cell granuloma, Langhans giant cells, and lymphocytes. These findings are typical for whi...
Type I
Type II
Type III
Type IV
3d
multi
Ans. is 'd' i.e., Type IV o Presence of epitheloid cell granuloma, Ianghans giant cells and lymphocytes is characteristic of chronic granulomatous inflammation
Pathology
null
e5a54479-48d8-4548-93dd-e640a37f1320
Nicotinic acid -
Increases HDL
Increased triglyceride synthesis
Type II hyperlipoproteinemia
Decreased hydrolysis of VLDL
0a
single
Ans. is 'a1 i.e., Increases HDL Nicotinic acid (Niacin)o There are three main type of lipases related to metabolism of lipoproteins -1. Lipoprotein lipase - Present in blood vessels and causes hydrolysis of tryglvceride content of VLDL and chylomicrones.2. Hepatic lipase - Converts IDL to LDL by hydrolysing the triglyc...
Pharmacology
Hypolipidemic
666192fd-9a22-4afd-8180-b69b38b8fe3a
Giant 'a' waves in JVP occur in all except -
Junctional rhythm
Pulmonay hypeension
Tricuspid regurgitation
Complete hea block
2c
multi
Because Tricuspid stenosis usually occurs in the presence of other obvious valvulardisease, the diagnosis may be missed unless it is considered. SevereTS is associated with marked hepatic congestion, often resultingin cirrhosis, jaundice, serious malnutrition, anasarca, and ascites.Congestive hepatomegaly and, in cases...
Medicine
C.V.S
51279d1a-41eb-416a-8973-f6e4f73d3f3f
The facultative anaerobic bacteria are those who are:
Unable to grow in the presence of oxygen
Unable to grow in the absence of oxygen
Able to grow in the presence of carbon dioxide
Able to grow in the presence or absence of oxygen
3d
single
null
Microbiology
null
1250a0d7-d557-4716-8a76-4b8cf4242fd9
Treatment of Hirsutism in PCOD, Drug used is :
Menopausal Gonadotropin
GnRH
Spironolactone
Hcg
2c
single
In PCOD with Hirustism,drugs given are; a.oral contraceptive b.anti androgens Antiandrogens in PCOD Used are spironolactone, cyproterone acetate, Flutamide and Finasteride Spironolactone in a dose of 100-200 mg daily, blocks the androgen receptors, reduces it production and increases its metabolism and thus prevents hi...
Gynaecology & Obstetrics
PCOD, hirsutism and galactorrhea
1039153c-553e-40db-bb19-bb54e696c3a9
Dermatophyte which does not involve nail
Trichophyton
Microsporum
Epidermophyton
None of the above
1b
multi
Trichophyton - Infect skin, Hair and nail. Microsporum - Infect skin, Hair. Epidermophyton - Infect skin, Nail.
Microbiology
null
85f512a5-2d0a-4fd6-a485-da9b5c7bb423
Which of the following is the right order of psycho-sexual development:-
Oral - Phallic - Anal - Latent - Genital
Oral - Anal - Latent - Phallic - Genital
Anal - Oral - Phallic - Genital - Latent
Oral-Anal-Phallic-Latent - Genital phase
3d
multi
Freudian psychosexual stages of developmen Stage Age Erogenous Zone/Activities Oral 0-1 1/2 years Sucking biting chewing Anal 1 1/2 - 3 years Bowel and bladder control Phallic 3-6 years Genitalia Latency 6 - pubey Repression of sexual instincts Genital After pubey Adult sexual inclinations and interests
Psychiatry
Psychiatry Q Bank
d3d8f25d-b337-4f95-a1dd-88a732da581b
Hypersecretory glaucoma is seen in-
Epidemic dropsy
Marfan's syndrome
Hypeension
Diabetes
0a
single
"In epidemic dropsy, the aqueous shows raised level of histamine, prostaglandin and protein suggestion that the glaucoma is hypersecretory". Ref: pediatric Ophthalmology by PK Mukharjee 4th/e p.370
Ophthalmology
Miscellaneous
3eae4df2-379c-4e28-87dc-f3ea2694e8c8
An HIV-positive patient asks you if you can tell him the chances of him progressing to symptomatic AIDS. Which one of the following tests would be most useful?
CD4 lymphocyte count
HIV antibody test
HIV PCR
Neopterin
2c
single
HIV PCR, a nucleic acid amplification test for HIV RNA, has recently been shown to be the most valuable test for: monitoring a patient's progress during triple drug therapy and determining the chances of progression to AIDS. A viral load of 750,000 copies per ml significantly increases the chance of progression to AIDS...
Microbiology
Virology (RNA Virus Pa-1,2 & Miscellaneous Viruses)
1dc7c9d3-fdc7-4853-a1ee-103586d19a68
Which of the following is the method of treating internal resorption:
Extirpation of pulp and calcium hydroxide dressing
b) Extirpation of pulp and formocresol dressing
c) Pulpotomy
Pulp capping
0a
single
null
Dental
null
4eec5b7a-ec4d-4b40-a20f-44366dbee9d0
Not seen in the first decade -
Retino blastoma
Rhabdomyosarcoma
Neuroblastoma
Ameloblastoma
3d
single
Ameloblastoma is not a childhood tumor. Other three are childhood malignancies.
Pediatrics
null