id
stringlengths
36
36
question
stringlengths
1
1.57k
opa
stringlengths
1
287
opb
stringlengths
1
287
opc
stringlengths
1
286
opd
stringlengths
1
301
cop
class label
4 classes
choice_type
stringclasses
2 values
exp
stringlengths
1
22.5k
subject_name
stringclasses
21 values
topic_name
stringlengths
3
135
0f389694-d6a7-4907-bc43-7050a1651554
Genu of internal capsule carries:
Optic radiation
Coicospinal
Coicorubral tract
Coiconuclear tract.
3d
single
D i.e. Coiconuclear
Anatomy
null
d1ac0e0c-88e3-4471-9a25-1b91c90d1941
All are contents of axilla, except
Axillary tail of breast
Axillary vessels
Axillary sheath
Roots of brachial plexus
3d
multi
AXILLA: Is a pyramidal space situated between the upper pa of the arm and the chest wall. CONTENTS: 1)Axillary aery and its branches. 2)Axillary vein and its tributaries. 3)Infraclavicular pa of the brachial plexuses. 4)Five groups of axillary lymph nodes and the associated lymphatics. 5)The long thoracic and intercost...
Anatomy
Upper limb
bc2fdf3a-fb37-405a-babe-f18e31071657
Ptosis results from trauma to which nerve-
VII
VIII
III
VI
2c
single
*Ptosis is due to occulomotor nerve paralysis. Ref: Principles of ophthalmology 4th/e p.1107
Ophthalmology
Diseases of orbit, Lids and lacrimal apparatus
a88a722c-7729-4e3b-9076-f16c9fbdfde7
Effect of inhalational agent on neuromuscular system which is true -
They relax skeletal muscle and decreases the effect of neuromuscular blocking drugs (NMBD)
They contract skeletal muscle and potentiate the effect of NMBD
They directly relax skeletal muscle and they potentiate the action of NMBD
No effect on neuromuscular system
2c
multi
Halogenated volatile anesthetics have a potentiating effect on nondepolarizing muscle relaxants. The mechanism appears to be incompletely understood, but is likely a combination of: effect on central motor neurons augmentation of the NMB's affinity for the receptor site inhibition of post-synaptic nicotinic acetylcholi...
Anaesthesia
Inhalational Anesthetic Agents
ac497c9c-268b-45da-90a8-420341092240
Cell type which lacks HLA antigen is -
Monocyte
Thrombocytes
Neutrophil
Red blood cell
3d
single
Class I products of the genes of the major histocompatibility complex (MHC), HLA-A, -B, and -C, are present on viually all nucleated cells. Mature human red blood cells are not nucleated and do not generally have easily detectable HLA antigens, Reff: www.mayoclinin.com
Microbiology
Immunology
f51f9f5e-54cf-4e72-9cce-6be1b6d40d0f
Which one of the following is diagnosed by latex agglutination for antigen in CSF?
Cryptococcus
Aspergillosis
Candida
Histoplasmosis
0a
single
(A) Cryptococcus # Approximately 90% of patients with cryptococcal meningoencephalitis, including all those with a positive CSF smear, have capsular antigen detectable in CSF or serum by latex agglutination.# Certain important points about cryptococcus> Cryptococcus is the only pathogenic yeast> It is characterized by ...
Microbiology
Misc.
f67c0016-35f7-479b-8499-0825b200e3ff
Tamsulosin, a competitive α adrenoceptor antagonist has an affinity for which of the following receptors
α1A
α1D
None of the above
Both (a) and (b)
1b
multi
The actions of the α1-adrenoceptor antagonist tamsulosin have been examined at functional α1-adrenoceptor subtypes and compared with those at the human prostate receptor. At the α1D-adrenoceptors of the rat aorta, tamsulosin acted as a competitive antagonist with a high affinity (pKB=10.1). At the α1B-adrenoceptor of t...
Pharmacology
null
958f79f2-2050-42d6-bc36-7566da27961b
"MAC" of desflurane is:
1.15
2
4
6
3d
single
In 20-30 year old patients Minimum Alveolar Concentration(MAC)for Halothane. 0.75 Isoflurane. 1.15 Sevoflurane. 1.85 Desflurane. 6 From Tripati 7th edition
Pharmacology
Anesthesia
cd482bc2-4e0f-4cd2-8771-52704416f367
Drugs used in the treatment of MRSA are :
Quinupristin\/dalfopristin
Atropine
Teicoplanin
Penicillin G
0a
single
Staphylococcal infections are usually caused by Staphylococcus aureus. However, the incidence of infections due to Staphylococcus epidermidis and other coagulase-negative staphylococci has also been steadily rising. Pharmacotherapy Patients with serious staphylococcal infections should be initially staed on agents acti...
Pharmacology
Chemotherapy
4531f49d-73ac-4182-8210-835f4397583d
True about Pertussis is/are -a) Incubation period is 7-14 daysb) Main source of infection is chronic carriersc) Can affect any aged) Secondary attack rate in unimmunised persons is 90%e) More common in summers
abc
acd
bc
bde
1b
multi
null
Social & Preventive Medicine
null
a56f32f1-2244-45b7-82cc-6c546172bd61
Treatment of stage III B carcinoma cervix is:
Wertheim procedure
Schauta's procedure
Chemotherapy
Intracavitary brachytherapy followed by external beam RT
3d
single
Ans. is d, i.e. Intracavitary brachytherapy followed by external beam RT.Ref: Novak 14th/ed, p1436, 1427; Shaw 15th/ed, p414The best treatment for stage III B of invasive cancer is chemoradiation. Since this option is not given - we will go for next best option, i.e. RadiotherapyGenerally from stage II a-IV A when radi...
Gynaecology & Obstetrics
Carcinoma Cervix
a232a659-f439-4b65-9a67-1fe501a9d2d6
Muller's manoeuver is
Forceful expiration against closed glottis
Forceful inspiration against closed glottis
Forceful expiration against open glottis
Reverse of Valsalva's maneuver
3d
single
Muller's manoeuvre: Used to find the level and degree of obstruction in sleep-disordered breathing. It is performed while using flexible nasopharyngoscope. First, the examiner sees the upper airways at rest and then during the time when the patient makes a maximal inspiratory effo with nose and mouth closed. The base o...
ENT
Miscellaneous ENT
3a4fc6d9-0cf9-4904-bbd8-ec6dbb34070b
Which of the following fungus does not infect hair
Epidermophyton
Microsporum
Trichophyton
None of the above
0a
multi
Trichophyton infects hair, skin and nail. Microsporum infects hair and skin. Epidermophyton infects skin and nail. Reference: Textbook of Microbiology; Baveja; 4th edition
Microbiology
mycology
cfd8e300-58a3-4f67-83f6-8a75e3ab39be
APACHE-II score includes
Age
Blood pressure
Pa02
All
3d
multi
Acute Physiologic Assessment and Chronic Health Evaluation II (APACHE II) score generates a point score ranging from 0 to 71 based on 12 physiologic variables, age, and underlying health. The point score is calculated from a patient's age and 12 routine physiological measurements: AaDO2 or PaO2 (depending on FiO2) Temp...
Medicine
C.N.S
bffc87c0-841a-47f7-8a66-dd6eed8fbff4
Obsessive personality disorder is also called:
Anankastic personality disorder
Dissocial personality disorder
Eccentric personality disorder
Histrionic personality disorder
0a
multi
Obsessive-compulsive personality disorder (OCPD), as defined by the current version of DSM-5, and termedanankastic personality disorder in the ICD-10. Pre occupation with rules and regulations Perfection that slows them down Stubborn and inflexible Impoant to work, no time for leisure activities Formal, don't like humo...
Psychiatry
Personality Disorders
cc391afe-e381-4374-a25e-58a56bc4e2b2
Position of internal hemorrhoid in anus is especially common in -
4 o' clock position
11 o' clock position
8 o' clock position
9 o' clock position
1b
multi
Ans. is 'b' i.e., 11 o' clock position Classification of hemorrhoids|||Internal hemorrhoidsExternal hemorrhoids* Located proximal to the dentate line* Covered by transitional and columnar epithelium therefore are usually painless* Internal haemorrhoids (Greek: haima, blood; rhoos, flowing; synonym: piles, Latin: pila, ...
Surgery
Anal Canal
8c6aac4d-e5d8-48ba-8a9d-9b3e5dc06904
Women with PCOD and Hirsutism, Management is
Ethinyl estradiol + Cyproterone Acetate
Ethinyl estradiol
Levonorgestrel
Ethinyl estradiol + Levonorgestrel
0a
single
Treatment of Hirsutism Estrogen-Progestin Contraceptives Antiandrogens Mechanism of action Androgen production in hirsuite women usually is an LH-dependent process Estrogen-progestin contraceptives suppress pituitary LH secretion and thus suppress ovarian androgen production The high level of estrogen in oral c...
Gynaecology & Obstetrics
null
560aff8f-699e-411d-87f6-465c23101eb5
Schwangerschafts protein 1 (SP1), is a biochemical marker of-
Gestatinal trophoblastic disease
Ectopic pregnancy
Placenta accreta
Severe PIH
1b
single
Schwangerschafts protein 1 (SP1), also known as pregnancy-associated plasma protein C (PAPP-C) or pregnancy-specific b-glycoprotein (PSBS), is produced by the syncytiotrophoblast . It is a biochemical marker of Ectopic pregnancy
Gynaecology & Obstetrics
Ectopic Pregnancy (Hello ! Where are you ?)
79526aad-9986-43f2-8f3d-5fc2bf9fc84a
All drugs cause interstitial lung disease, except :
Phenytoin sodium
Sulfonamide
Busulfan
Alpha methyldopa
3d
multi
Drugs causing interstitial lung disease are: Amiodarone Nitrosoureas Busulfan Phenytoin Methotrexate Sulfonamides Penicillamine Cyclophosphamide Nitrofurantoin Gold salts Bleomycin
Pharmacology
null
0c46aaa4-5c0c-42e2-b79c-225704233774
Strored blood, which h. as been preserved in a blood bank, is deficient in which of the following coagulation factors?
II only
II and VII
V and VIII
IX and X
2c
single
The temperature in all areas of a refrigerator used for the storage of Red Blood Cells must be maintained between 1 and 6degC, and should have a fan for circulating air or be of capacity and design to ensure that the designated temperature is maintained and the blood may be deficit of v and vlll coagulation factors Ref...
Medicine
Miscellaneous
6c5f4fca-2545-4ce1-bd6d-ad633ed9c991
The life of preserved semen for aificial insemination is -
One year
Two year
Five year
Ten year
3d
single
Ans. is 'd' i.e., Ten years
Surgery
null
f5cf2e26-c94e-417d-bb55-d0594509fbbb
Source of maltose is
Beet sugar
Milk
Germinating Cereals
Yeast
2c
single
SugarSourceSucroseCane and beet sugar, sorghum and some fruits and vegetablesLactoseMilkMaltoseEnzymic hydrolysis of starch (amylase);germinating cereals and maltIsomaltoseEnzymic hydrolysis of starch (the branch points in amylopectin)LactuloseHeated milk (small amounts), mainlysyntheticTrehaloseYeasts and fungi; the m...
Biochemistry
Structure and function of protein
dab8cd7f-e83e-48c4-b080-b18effec8126
A 45-year-old woman visits the outpatient clinic with past history of dysphagia, nighttime fits of coughing, repeated chest infections, and a palpable swelling in her neck. Radiographic examination reveals the presence of a congenital pharyngeal pouch. Between which muscles is this pouch located?
Between styloglossus and stylopharyngeus
Between palatoglossal arch and median glossoepiglottic fold
Between upper and middle pharyngeal constrictors
Between the cricopharyngeal and thyropharyngeal portions of inferior pharyngeal constrictor
3d
single
The pharyngeal (Zenker) diverticulum is usually located between the cricopharyngeal and thyropharyngeal portions of the inferior pharyngeal constrictor. This is the most common site for development of a pharyngeal diverticulum due to the inherent weakness between the pharyngeal muscles in this location. Stasis of mater...
Anatomy
Head & Neck
ed9ec054-423c-44f9-855d-2c5e0764e3ad
Which of the following statements is true regarding kappa, lambda and heavy chain immunoglobins -
Coded in the same site of a chromosome
Coded in different sites of same chromosome
The chains are formed by genetic rearrangement after maturation
Different chains of same immunoglobulins are coded by different chromosomes
2c
multi
The variable region of each immunoglobulin heavy or light chain is encoded in several pieces--known as gene segments (subgenus). These segments are called variable (V), diversity (D) and joining (J) segments.V, D and J segments are found in Ig heavy chains, but only V and J segments are found in Ig light chains. Multip...
Microbiology
Immunology
edfedc44-beed-43b9-9158-8cf995e4010d
Differentiating features b/w neurosis and psychosis :
Insight is preserved
Lack of insight
Personality and behavior preserved
None
1b
multi
B i.e. Lack of insight
Psychiatry
null
a94e5850-fe52-44da-884e-48afb9027014
Which of the following is used to differentiate tumour recurrence and radiation necrosis?
PET scan
MRI
3D CT
USG
0a
single
ANSWER: (A) PET scanREF: Devita oncology 6th ed chapter 27PET may be used in therapeutic monitoring after chemotherapy or radiotherapy, with a classic indication being assessment for recurrent tumor versus radiation necrosis. Conventional imaging can not differentiate recurrent tumor from radiation necrosis
Unknown
null
2d11feca-87b7-41c4-b065-6ea655f7fada
Drugs associated with ischemic stroke include the following except
Cocaine
Oral contraceptives
Amphetamines
Barbiturates
3d
multi
*misuse of oestrogen containing drugs like oral contraceptive pills ,hormone replacement therapy,cocaine ,amphetamine,alcohol are modifiable risk factors of ischemic stroke . Ref Harrison20th edition pg 2445
Medicine
C.N.S
8e232f96-bb5b-4125-994f-314ea89fc37e
All are seen in malignant hypehermia except:
Bradycardia
Hyperkalemia
Metabolic acidosis
Hypeension
0a
multi
A i.e. Bradycardia
Anaesthesia
null
4b65c2ec-05cd-495d-bd14-b2f3a42ec4a5
In a case of anisocoria, when 1% pilocarpine le is instilled into the eye with abnormally dilated pupil, no response occurs. Cause of anisocoria may be:
Adie's pupil
Horner's syndrome
Pharmacological blockage
Uncal herniation
2c
multi
Ans is 'c' i.e. Pharmacological blockage Anisocoria (inequality of pupillary size) implies disease of the efferent (motor) nerve of the light reflex, iris or muscles of the pupil.If, on application of pilocarpine 1% in each eye, the affected pupil reacts little or not at all and the unaffected pupil constricts normally...
Ophthalmology
Pupillary Reflexes and their Abnormalities
3f5caf62-1ed6-4cbf-b74d-8ec3e307ab6c
Tracheostomy is not indicated in:
Emphysema
Bronchiectosis
Atelectasis
Pneumothorax
3d
single
null
ENT
null
b610c8ac-fc6a-489f-b551-381df941f170
A patient presents with cough with expectoration. Diagnosis of farmer's lung is suspected. True statement regarding this condition:
May to June seasonal
Persistent cough with expectoration
X- ray features upper lobe predominant in chronic HP
Pleural effusions are common
2c
multi
Farmer`s lung:- caused by Thermophilic Actinomycetes it is occupational disease - So, no seasonal predilection occur in Asthma - Hypersensitivity pneumonitis occurs due to inhalational exposure to variety of antigens leading to inflammatory response of alveoli and small airways. Choice A is ruled out as asthma attacks ...
Medicine
JIPMER 2018
112ff6c3-1262-4854-8e59-a697fd7a98b7
A deficiency of 5-8 mm usually requires extraction of:
First molars
Second premolars
First premolars
Second molars
2c
multi
null
Dental
null
24c407e2-d709-4843-8be8-76a28d89076c
Most common tumour occurring in appendix includes
Carcinoid tumour
Melanoma
Adeno carcinoma
Mucinous
0a
single
Carcinoid tumours arise in argentaffin tissue (Kulchitsky cells of the crypts of Lieberkuhn) and are most common in the vermiform appendix.The tumour can occur in any pa of the appendix, but it is frequently found in the distal third Ref: Bailey & Love&;s Sho Practice of Surgery,E25,Page-1217
Surgery
G.I.T
33b85685-5608-4533-bd25-7db2372e049f
HIV contains: March 2013
Integrase
RNA directed DNA polymerase
Ribonuclease
All of the above
3d
multi
Ans. D i.e. All of the above HIV virus It is composed of two copies of positive single-stranded RNA that codes for the virus's nine genes enclosed by a conical capsid composed of 2,000 copies of the viral protein p24. The single-stranded RNA is tightly bound to nucleocapsid proteins, p7, and enzymes needed for the deve...
Microbiology
null
158c4658-58b3-4ba8-8aa7-d910cb40eaac
Rigor mortis start in -
Eyelids
Heart
Voluntary muscles
Limbs
1b
single
null
Forensic Medicine
null
099ded4d-af93-4938-bcc1-a052fb3d9fd6
Most common type of RCC associated with dialysis:
Clear cell CA
Papillary CA
Medullary CA
Chromophobe
1b
single
Ans. (b) Papillary CA
Unknown
null
8a0df935-4989-4600-a61a-887f08c92fc6
All are true about Erythema multiforme except
Target lesion
Does not involve mucosa
Associated with HSV
Extensor involvement
1b
multi
null
Medicine
null
5e87322a-3be9-4b85-8497-0a5778ab5da6
Which of the following is true about Ganer cyst ?
It is remnant of Mesonephric duct in females.
It is functionally active in females.
It is remnant of Paramesonephric duct in females.
In males,it forms excretory system of male reproductive system.
0a
multi
Ganer cyst is basically a remnant of mesonephric or wolffian duct which remains vestigeal and functionally inactive in females. In males it forms collecting pa of male reproductive system.
Anatomy
Development of GU system and Neuro-vascular supply of pelvis & perineum
3ef7c2b9-06b0-419a-af6a-3171fa549bea
Main mechanism in thermoregulation-heat loss is
Radiation
Evaporation
Conduction
Convection
0a
single
Heat is lost from the body mainly by radiation (60%), evaporation (22%) and Conduction (18%).
Physiology
null
7beda74e-899b-435a-8b56-2914b35d413d
Which of the muscle in male is equivalent for vaginal sphincter in female?
Levator prostatae
Anococcygeal body
Puborectalis
Bulbospongiosus
0a
single
The sphincter vaginae (levator prostatae in the male) form a sling around the vagina and are inseed into a mass of fibrous tissue, called the perineal body. Ref: Clinical Anatomy by Systems By Richard S. Snell, 2007, Page 861.
Anatomy
null
2342d699-05cc-4929-a455-98f4edb75bc2
Drug of choice for CML is?
Imatinib
Hydroxurea
Infliximab
IFN
0a
single
ANSWER: (A) ImatinibREF: Harrison s 17th ed, CMDT 2008 p. 444The drug treatment of choice for CML when Allogenic SCT (stem cell therapy) is not feasible is IMATINIBIFN-tz used to be the drug treatment of choice for CML when IMATINIB was not available
Medicine
Blood
bb0e4fdd-cc3e-4a34-8aa7-28f0eed417af
The ideal replacement for the oesophagus after oesophagus after esophagectomy is
Stomach
Jejunum
Colon
Synthetic stent
0a
single
.Only 20% of oesophageal cancers present early and becomes curable. In such early growths confirmed with an absence of nodal spread, curative surgery is the main approach - radical oesophagectomy. Proximal extent of resection should be 10 cm above a macroscopic tumour and distal extent of resection is 5 cm from the mac...
Surgery
G.I.T
c4ad4e9f-6c50-44f6-a069-e4d5df742920
Egg has all vitamins except -
B1
B6
C
E
2c
multi
Expect vitamin C, egg contain all fat soluble vitamin. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION. PAGE NO - 582
Social & Preventive Medicine
Nutrition and health
e9e4d293-04ea-45a8-a654-63cad69b26d0
Lewy bodies contain
a-synuclein
Tirofiban
Melanin
Amyloid
0a
single
(A) a-synuclein # Examination of brain in Parkinson's Disease (PD):> Grossly reveals mild frontal atrophy with loss of the normal dark melanin pigment of the midbrain.> Microscopically there is degeneration of the dopaminergic cells with the presence of Lewy bodies (LBs) in the remaining neurons and processes of the su...
Medicine
Miscellaneous
46a0da3b-973e-48dd-9857-78b894ea50bf
Which peak on MR spectroscopy is seen in tuberculoma?
Lipid lactate
N-acetyl aspaate
Creatinine
Choline
0a
single
MR-spectroscopy usually reveals a large lipid lactate peak at 0.9 to 1.33 ppm and reduced NAA. The lipid peak in tuberculoma is primarily due to the predominant lipid content in the cell wall of tubercle bacillus. Presence of lactate indicates anaerobic glycolysis and necrosis within the Tuberculoma. However, lipid lac...
Radiology
Magnetic Resonance Imaging
7fb02341-81c1-498b-aad1-65cfca6cb00c
In Wilson disease, hepatic copper content usually exceeds_____________ dry weight
200 mg/g
250 mg/g
300 mg/g
350 mg/g
1b
multi
In Wilson's disease, hepatic copper content usually exceeds 250 mg/g dry weight (>4 mmol/g dry weight is the best biochemical evidence for Wilson disease).
Pediatrics
Liver disorders
09a7f48a-9ace-411e-a20a-d9c58bd2e3c0
Lunate sulcus is present in
Frontal lobe
Parietal lobe
Temporal lobe
Occipital lobe
3d
single
The occipital lobe sulciA. Transverse occipital B. Lateral occipital C. Lunate D. Superior and inferior polarReference: Chaurasia; 6th edition; 417 page
Anatomy
Brain
05b22f8a-162c-4d8c-be93-945710006c5b
Regarding transpo of Ca++ across a membrane, which of the following is true?
It is a passive transpo
It is a sympo
Maintains a high intracellular Ca++ concentration
Requires hydrolysis of ATP
3d
multi
Calcium transpo occurs by secondary active transpo. Hence, option A is incorrect It is an antipo or counter transpo; occurring as Na+/ Ca++ exchanger. Hence, option B is incorrect It is primarily aimed at maintaining a low cytosolic Ca++. Thus, option C is incorrect. To maintain a low intracytoplasmic Ca++, calcium is ...
Physiology
Transpo Processes
aa4728dd-8af6-4734-8c18-593d8c079796
Adenovirus causes -
Keratoenjuctivitis
Diarrhea
Parotid enlargement
All of the above
0a
multi
It causes epidemic keratoconjunctivitis REF:ANANTHANARYANAN TEXTBOOK OF MICROBIOLOGY 9EDITION PGNO.482
Microbiology
Virology
f93da77e-09c0-47ae-bc2d-15100d0511bf
Testosterone in male secreted from:
Leydig cell
Sertoli cell
Seminal vesicle
Epididymis
0a
single
Ans. (a) Leydig cellRef: LB. Singh 9th ed. /14-16* Leydig cell secrete testosterone* Sertoli cells helps in maturation of spermatozoa* Epididymis:store sperm* Seminal vesicle: secretes thick alkaline fluid.
Anatomy
Male Sex Glands
7706664f-dfc9-49e3-98da-4abc42791f3f
Role of neo-adjuvant chemotherapy in breast carcinoma patient is: March 2011
Curing distant metastasis
To shrink the tumour to enable breast conserving therapy
Limiting metastasis
Symptomatic
1b
single
Ans. B: To shrink the tumour to enable breast conserving therapy Primary chemotherapy (neoadjuvant) is being used in many centres for large but operable tumours that would traditional require a mastectomy (and almost ceainly postoperative adjuvant chemotherapy) The aim of this treatment is to shrink the tumour to enabl...
Surgery
null
276160b3-9695-4aa9-94dd-a97b86785c36
Sialography report of a 46-year-old female suggests:
Sialiolithiasis.
Normal parotid appearance.
Sjogren syndrome.
None.
2c
multi
Image shows cherry blossom appearance.
Pathology
null
7163f860-82f2-44f6-ba64-dc394ae5b1b8
Which response is not seen in newborns as a measure of thermogenesis?
Shivering
Breakdown of brown fat
Universal flexion
Cutaneous vasoconstrictions
0a
single
ANSWER: (A) ShiveringREF: O.P Ghai 6th ed p. 151,152"Newborn cannot produce heat by shivering"Mechanisms for thermogenesis in new born are mainly due to rapid increase in circulating catecholamines due to cold stressLipolysis and re-esterification of brown fatPeripheral vasoconstrictionIncrease heart rate
Pediatrics
Newborn Infant - Physical Examination
f71815e1-abe4-414e-b903-c097a31267fd
Which of the following is more prone to Carcinoma?
Barret esophagus
Boerhaave syndrome
Mallory Weiss tear
Esophageal varices
0a
multi
Ans. (a) Barrett esophagusRef: Bailey & Love 26th ed. ch 62! 1000* Barrett's metaplasia, endoscopically recognized by tongues of reddish mucosa extending proximally from the gastroesophageal junction or histopathologically by the finding of specialized columnar metaplasia (intestinal type with goblet cells), is associa...
Surgery
Esophageal Diseases - Gastroesophageal Reflux Disease, Carcinoma
d05b04d5-f285-4fad-ba3e-c3433ddb68d2
Berkesonian bias refers to -
Bias arsing from different rates of admission to the hospital
Bias arising from presence of confounding factors
Bias arising from the case not being representative of general population
Bias arising from improper selection of cases
0a
single
This special example of berkesonian bias is termed after Dr. Joseph Berkesonian who recognized this problem. Ref: 25th edition, Park's Textbook of Preventive and Social Medicine, Page no. 81, 82
Social & Preventive Medicine
Epidemiology
3434c6e4-7513-482e-bd83-8b3d6bfd5ef0
Which does not indicate fetal lung maturity' -
Reactive NST
Gestation 37 weeks
Presence of phosphatidyl choline
L/S ratio
0a
single
Ans. is 'a' i.e., Reactive NST
Gynaecology & Obstetrics
Fetal Assessment
339e8ba7-6b74-497b-96ec-3dc4aced515a
A 20 years old nulliparous women is on oral contraceptives pills. She is currently diagnosed as having pulmonary tuberculosis. Which anti-tubercular drug decreases the effect of OCP
INH
Pyrazinamide
Ethambutol
Rifampicin
3d
single
Ans. is d i.e. Rifampicin Interacuons of OCP's with other Drugs
Gynaecology & Obstetrics
null
e91c317c-8241-4698-9406-b8dbfbe17fb1
All are toxicity seen with amiodarone therapy except
Pulmonary fibrosis
Corneal microdeposits
Cirrhosis of liver
Productive cough
3d
multi
Refer katzung 11e p 241 Amiodarone-induced pulmonarytoxicity (APT) is one of the most serious side effects of use. Incidence is approximately 5% when doses of 400 mg or more are used daily. ... Amiodarone pulmonarytoxicity can present in various ways: pneumonia interstitial disease, respiratory distress or solitary pul...
Anatomy
General anatomy
eb6e9bf6-0917-4102-bae0-a39998dc7a5b
Cerebrospinal fluid is filled between:
Dura mater and arachnoid mater
Arachnoid mater and Pia mater
Pia mater and Brain surface
Dura mater and Pia mater
1b
single
Subarachnoid space is a wide space between the pia and the arachnoid, filled with cerebrospinal fluid (CSF). It surrounds the brain and spinal cord like a water cushion. The spinal subarachnoid space is wider than the space around the brain. It is widest below the lower end of the spinal cord where it encloses the caud...
Anatomy
null
5220900c-0455-46e8-8887-3ef5fd472a17
Stroke volume is increased by ?
Increased end-diastolic and end-systolic volumes
Decreased end-diastolic and end-systolic volumes
Increased end-diastolic volume and decreased end-systolic volume
Decrased end-diastolic volume and increased end-systolic volume
2c
single
Ans. is 'c' i.e., Increased end-diastolic volume and decreased end-systolic volumeThe stroke volume is the amount of blood pumped out by left ventricle in each stroke.Stroke volume is given by the difference between end-diastolic ventricular volume (the volume of blood in the left ventricle at the end of diastole; norm...
Physiology
null
15f23eb5-8df6-403f-acb6-f47f411eb7da
No anti - inflammatory action is seen with which of the following-
Indomethacin
Paracetamol
Ketorolac
Ibuprofen
1b
single
Ans. is 'b' i.e., Paracetamol o It does not possess anti-inflammatory activity because it is ineffective in the presence of peroxides generated at the site of inflammation.
Pharmacology
null
424a595e-fdc3-44f9-b721-2edd96753473
Westermark sign is seen in:
Pulmonary embolism
Pulmonary sequestration
Pulmonary alveolar proteinosis
Pneumothorax
0a
single
Ans. (a) Pulmonary embolism Ref- Westermark sign is a sign of pulmonary embolus seen on chest radiographs. It is one of several described signs of pulmonary embolus on chest radiographs. Pathology The theory behind the sign is either obstruction of the pulmonary artery or distal vasoconstriction in hypoxic lung 3. In o...
Unknown
null
f9fd7fd3-0b91-487d-a2be-6e98101abd6a
True about Congenital Rubella syndrome is
It will become a chronic infection
Virus can be isolated only upto 6months after bih
Triad of CRS are cataract, cardiac defects, cerebral palsy
Infection is most serious after five months of pregnancy
0a
multi
* Rubella infection gets transmitted by veical transmission and bih defects is more common when acquired during first trimester of pregnancy. * Bih defects are uncommon when infection is acquired after 20 weeks of gestation. * Congenital Rubella syndrome leads to cardiac defects, cataract and deafness; (Classical triad...
Microbiology
Virology
02c32231-a5d0-47c9-ada2-6cbf18797f1a
Scarring alopecia is seen in -
T.Capitis
Androgenic alopecia
Alopecia areata
Lichen planus
3d
single
Causes of cicatricial alopecia: -Discoid lupus erythematosus and morphea - developmental /hereditary : aplasia cutis -traumatic, post radiation -herpes zoster and bacterial infections -lichen planopilaris - neoplastic disorders Ref Harrison20th edition pg 1234
Dental
Anatomy of skin
a84b619f-eae4-4634-b60b-4cc420014ec1
Donesumab, a monoclonal antibody against RANK ligand is used for the treatment of:
Rheumatoid arthritis
Osteoporosis
Osteoarthritis
Systemic lupus erythematosis
1b
single
Ans. (B) Osteoporosis(Ref: Principles of pharmacolpg HL Sharma and KK Sharma 2007/641)Receptor for activated nuclear factor kB (RANK) is present on osteoclast progenitors. Binding of RANK-ligand to these receptors causes differentiation and activation of osteoclast progenitors to mature osteoclasts. Donesumab is a mono...
Pharmacology
Immunomodulatory: DMARDS, Monoclonal Antibodies
4751aa6f-f229-4e0e-9c5a-6d3089dfd11d
Type IV hypersensitivity is -
Ig E mediated
Immune complex mediated
Cell mediated
Antibody mediated
2c
single
Ans. is 'c' i.e., Cell mediated Cell mediated (Type IV) hypersensitivity o It is initiated by activated T-lymphocytes. o It includes Delayed type hypersensitivity - mediated by CD-4 T cells. T-cell mediated cytotoxicity - mediated by CD8- T cells. 1. Delayed type hypersensitivity In delayed hypersensitivity reactions, ...
Pathology
null
3f9efec2-d27f-4f64-a42d-b8aab523f023
The sulphur granules in the wound are diagnostic of:
Nocardia
Actinomyces
Clostridium welchii
Aspergillus flavum
1b
single
Actinomyces
Microbiology
null
cd54d597-0155-44e7-a3e5-1f4b1350a7c6
Infraorbital anesthesia involves which nerve:
Anterior superior alveolar nerve
Posterior superior alveolar nerve
Facial nerve
Mandibular nerve
0a
single
null
Surgery
null
b83abaf5-f646-4f09-87f6-f05527fba941
Vector borne diseases are – a) Syphilisb) Typhusc) Dengued) J.E.
abc
bcd
ac
bd
1b
single
null
Social & Preventive Medicine
null
ade59ff2-068c-4266-86a5-71f7a110aa27
Which one of the following deficits results from the destruction of the ciliary ganglion?
Loss of corneal reflex
Loss of direct pupillary reflex
Loss of lacrimation
Miosis
1b
single
Destruction of the ciliary ganglion interrupts postganglionic parasympathetic fibers, which innervate the sphincter pupillae and ciliaris; this results in- loss of the direct pupillary reflex, mydriasis, and loss of accommodation.
Anatomy
Neuroanatomy 3
689aa2a9-b56f-4cf5-b3e5-6a3aa0a4870f
Loosers Zones/ Pseudofractures are commonly seen in the following areas except -
Scapula
Ribs
Pelvis
Radius
3d
multi
Answer- D. RadiusScapulaMedial femoral neck & shaftPubic & Ischial ramiLesser trochanteRibs & clavicleProximal ulna & radiusPhalanges, metacarpals & metatarsals
Surgery
null
3d4c9a31-81f6-415b-9433-c81ad9dcf445
Psammoma bodies features are all except:
Seen in meningioma
Concentric whorled appearance
Seen in papillary thyroid carcinoma
Seen in teratoma
3d
multi
Ans. (d) Seen in teratoma(Ref: R 9th/pg 65; 8th/pg 38)Psammoma bodies (PBs) are concentric lamellated calcified structures, observed most commonly in papillary thyroid carcinoma (PTC), meningioma, and papillary serous cystadenocarcinoma of ovaryThey represent a process of dystrophic calcification
Pathology
Cellular Pathology
52eff98b-36b7-4295-b175-ac544a6385e9
Test for detection or old blood stain is -
Gel diffusion
Precipitin test
Absorption elution test
Benzidine test
3d
single
Amongst the given options, only benzidine test is used to detect the nature of stain, i.e. whether it is blood or not.
Forensic Medicine
null
049a3117-5420-4562-9b0d-cca0da3c4c1d
Cirrhotic ascites has all the features except
Straw colour
Specific gravity < 1060
Leucocyte count < 200/cu mm
Serum ascitic albumin gradient <1
3d
multi
Serum-ascites albumin gradient g/dl > 1.1 in ascitic fluid caused by cirrhosis
Pathology
All India exam
6f67f33e-8594-485f-92c2-18986a4c05fa
Myasthenia gravis may be associated with
Thymoma
Systemic lupus erythematous
Hypehyroidism
All the above
3d
multi
Ref Robbins 7/e p1344; 9/e p1235-1236; Harrison 16/e p2521 table 366-3 MYASTHENIA GRAVIS (MG) is an autoimmune disease characterized by impaired neuromuscular transmission due to circulating antiacetylcholine receptor autoantibodies (AchRAb) (1). The frequent association of MG with thymic disease, such as follicular hy...
Anatomy
General anatomy
efc3c8e5-0d20-445b-834e-401cce6ce600
The recognized behaviour in a society is called
Custom
Tradition
Culture
Folkways
3d
multi
null
Dental
null
920c9641-cd85-4fe0-bedc-1db132f31850
The maximum depression of the soft palate is recorded when Frankfort horizontal plane is
30° below the horizontal plane
10° below the horizontal plane
60° below the horizontal plane
80° below the horizontal plane
0a
single
null
Dental
null
6a2dd9ad-67e2-4be0-ac9c-33d46b521203
A Central midline neck swelling is noted in a 4 yr old girl posted for tonsillectomy. The swelling is, painless. mobile, and cystic, just below the hyoid bone of size 2x1.1x1cm. U/S showed a thick walled cystic lesion. Management would include
Surgical removal
Antibiotics
Percutaneous aspiration
Chest X-ray
0a
multi
Mid line cystic swelling, mostly just below hyoid is thyroglossal cyst. Treatment is surgical removal (Sistrunk operation).
Surgery
Endocrinology and breast
57eda9fd-1f08-4b35-abdf-0201a1b6287a
Mesh is sutured to the edge of the defect, this is called
Onlay mesh
Inlay mesh
Underlay mesh
Sublay mesh
1b
multi
A well-placed mesh should have good overlap around all margins of the defect, at least 2 cm but up to 5 cm if possible. Suturing a mesh edge to edge into the defect is inlay mesh, this is not recommended.The mesh can be placed:Just outside the muscle in the subcutaneous space (onlay); Within the defect (inlay) - only a...
Surgery
General surgery
9e13c593-2ecb-47fb-8121-3ecb7a90fd03
A patient presents with hematuria for many days. On investigations he is found to have calcifications in the wall of urinary bladder and small contracted bladder; most probable cause is
Schistosomiasis
Amyloidosis
Tuberculosis
Ca urinary bladder
0a
multi
Schistosomiasis sometimes heralded by painless, recurrent hematuria, dysuria, or urinary frequency. It is first suspected cause for hematuria in endemic areas (sub saharan africa) Long-term urogenital schistosomiasis results in fibrosis that may obstruct urinary drainage and result in organ dysfunction. Ultrasonography...
Surgery
Urology
fe1ff803-d606-48e6-96f0-c7fc620ada3a
Plasmapharesis is used in all of the following except
Myaesthenic crisis
Cholinergic crisis
Gullian Barre syndrome
Polymyositis
1b
multi
Plasmapheresis of the autologuous and exchange types is used to treat a variety of disorders, including those of the immune system, such as Goodpasture's syndrome, Guillain-Barre syndrome, lupus, Polymyositis , myasthenia gravis, and thrombotic thrombocytopenic purpura. Ref - pubmed.com
Medicine
Immune system
6a547af3-6fda-4a1d-bcec-cb8aff639d89
Conduction velocity of nerve is reduced in all of the following conditions, except
Acute Motor Axonal Neuropathy (AMAN)
Acute Inflammatroy Demyelinating Neuropathy(AIDP)
Hereditary Sencory Motor Neuropathy (HSM)
Multifocal Motor Neuropathy
0a
multi
Acute motor axonal neuropathy (AMAN) is a variant of Guillain-Barre syndrome. It is characterized by acute paralysis and loss of reflexes without sensory loss. Pathologically, there is motor axonal degeneration with antibody-mediated attacks of motor nerves and nodes of Ranvier The syndrome typically presents as a prog...
Medicine
C.N.S
425eef96-7df3-459f-a6b1-de49a5aaef9f
Antemoem burn differ from postmoem burns by all except
Pus in vesicle
Vesicle with hyperemic base
Vesicle containing air
Infammatory red line
2c
multi
Vesicle containing air. In Antemoem burns, vesicles contain serous fluids with proteins & chlorides while in postmoem burns vesicles contain air. Trait Antemoem Burns Postmoem Burns 1 Line of redness Present Absent 2 Veiscles Contain albuminous fluid and chlorides Contain air 3 Infection Pus and sloughing Nil 4 Healing...
Forensic Medicine
null
ad515212-cf7b-4391-bd35-38029343c63f
Alpha-fetoprotein in maternal serum and/or amniotic fluid is increased in all except -
Fetal neural tube defects
Down's syndrome
Anencephaly
Encephalocele
1b
multi
null
Medicine
null
867491aa-2a0a-4718-98ea-9d2493b5df89
All are true about panel discussion except –
Two way discussion
6 to 20 members participates
Chief members initiates
Each one prepares the topic of discussion
1b
multi
Panel discussion It is a two way communication. 4 - 8 persons who are qualified to talk about a topic and discuss a given problem in front of a large group or audience. The panel comprises a chairman. The chairman opens the meeting, welcomes the group and introduces the panel speakers. He introduces topic briefly and...
Social & Preventive Medicine
null
38a23996-6981-4dde-b46b-5aea79034fd9
All of the following are X-linked except:
G-6 PD deficiency
Hemophilia -A
Von Willebrandt's disease
Fragile X syndrome
2c
multi
Answer is C (Von Willebrand disease) : Von Willebrand disease is inherited as autosomal dominant disorder. It is not X-linked.
Medicine
null
015f8b1c-8bdc-4c2f-8e4b-1ee1b20f7ab6
A patient has a functional shift towards right due to cross bite, the indicated treatment is
Maxillary expansion bilaterally
Expansion of maxilla on the side of functional shift
Expansion of maxilla opposite to the side of functional shift
None of the above
0a
multi
null
Dental
null
06e5a8a8-3c34-4d25-9e5d-e9826bf954a1
Humoral immunodeficiency is suspected in a patient and he is under investigation. Which of the following infections would not be consistent with the diagnosis?
Giardiasis
Pneumocystis carinii pneumonia
Recurrent sinusitis
Recurrent subcutaneous abscesses
1b
single
Answer is B (Pneumocystis carinii pneumonia) : Pneumocystis carinii infections are associated with deficient cell mediated immunity and not with humoral immunodeficiency. Humoral immunodeficiencies i.e. predominantly antibody deficiencies are associated with recurrent serious infections with pyogenic bacteria and giard...
Medicine
null
9487b690-3d93-41e4-8557-c24c63c896d8
The resting uretric pressure ?
5-7 cm of Hp
15-30 cm of Hp
7-10 cm of Hp
0-5 cm of 1-120
3d
single
Ans. is 'd' i.e. 0-5 cm of H20 "Baseline or resting ureteral pressure is approx. 0 to 5 cm 1120, and superimposed ureteral contraction ranging from 20 to 80 cm H20 occur two to six times per minute." - Cambell's Urology
Surgery
null
a9f591a3-72f8-444e-833d-00a815205261
True about heat hematoma: PGI 12
Inside the brain
Between skull and dura mater
Between skull and pericranium
Between scalp and pericranium
1b
multi
Ans. Between skull and dura mater
Forensic Medicine
null
c9792efb-4131-42d6-9429-43d9da8ba0e3
Under National Cancer control Programme, oncology wings were sanctioned to -
Regional Cancer institutes
District Hospitals
Medical college Hospitals
Voluntary Agenecies treating cancer patients
2c
single
Ans. is 'c' i.e., Medical college Hospital o Government hospital and government medical colleges arc provided with a grant of Rs 3.00 crores for the development of oncology wing.
Social & Preventive Medicine
null
5953863f-3390-4116-b2b7-38668eb888ab
The first gastrectomy was performed in 1881 by ?
Mickuliz
Wolfer
Billroth
Moynihan
2c
single
Ans. is 'c' i.e., Billroth
Surgery
null
007d63f9-11b9-469f-a328-c18a4c84501f
Which of the following is not a second generation antihistamines
Cyclizine
Fexofenadine
Loratidine
Acrivastine
0a
single
Antihistamines are classified as first generation and second generation compounds on the basis of CNS penetration and anticholinergic propeies. first generation antihistamines can penetrate blood brain barrier and possess additional anticholinergic propeies which are lacking in second generation drugs. cyclizine is a f...
Pharmacology
Autacoids
f4f8798d-722a-4953-b10d-68751d8729e8
All of the following are features of post-tubal ligation syndrome except:
Abnormal menstrual bleeding
Dysmenorrhea
Pelvic pain
Dysparaunia
3d
multi
Ans. is d, i.e. DyspareuniaRef: Dutta obs 7th/ed, p 557Post ligation syndrome-Some patients after tubal ligation can experience post-ligation syndrome characterized by menstrual irregularities like menorrhagia, or irregular periods along with pelvic pain or congestive dysmenorrhea and cystic ovaries.It is vascular in o...
Gynaecology & Obstetrics
Contraceptives
9ca01d9e-2ad2-4492-9499-5402d270696e
Post coital test is used to assess :
Cervical factor
Vagical factor
Uterine factor
Nose
0a
single
Cervical factor
Gynaecology & Obstetrics
null
0bfed726-df32-491c-8da0-1a119cbf9404
Reid index is useful in the diagnosis of:
Chronic bronchitis
Bronchial asthma
Bronchiectasis
Emphysema
0a
single
Ref: Chapter 15. The Lung: page: 688: Robbins and Cot ran Pathologic Basis of Disease: 8th editionExplanation:* The Reid index is ratio of the thickness of the mucous gland layer to the thickness of wall between the epithelium and cartilage.The normal Reid index is 0.4 and it is increased in chronic bronchitis, usually...
Pathology
Obstructive Lung Diseases
e07bb19d-7b1f-4df4-afd7-5a920e400cd2
Secondary hemorrhage after hysterectomy usually occurs
Immediately
Within 2 days
Between 5-10 days
Between 10-14 days
2c
multi
Ans. c (Between 5-10 days) (Ref. Dutta Gynecology 4th ed., 208; Shaw's Gynecology, 14th ed., p 228)# Hemorrhage (COMPLICATIONS OF HYSTER CTOMY)- Primary: within 24 hours (due to slipping of ligature usually that of vaginal angle)- Secondary: usually between 5-10 days (but may occur even in 3rd week)
Gynaecology & Obstetrics
Operative Gynaecology
e79c7cad-3b1f-4f3f-93a8-e7f6af647e3b
A 67-year-old woman has pulmonary function tests performed to evaluate symptoms of dyspnea. The most prominent finding is a reduction of the ratio of FEV1/FVC. Which of the following is the most likely diagnosis?
COPD
ankylosing spondylitis
Pickwickian syndrome
scleroderma of the chest wall
0a
multi
The VC is reduced in emphysema, but the FEV1 is grossly reduced because of high airway resistance. In predominant emphysema, diffusing capacity is more profoundly decreased than in predominant bronchitis.
Medicine
Respiratory
c3af2db1-c075-4a9f-8a06-752268d371cf
If 100 woman experience 20 accidental pregnancies after using a contraceptive method for 2 years each, Pearl index:
0.1 per 100 women years
100 per 1000 woman years
10 accidental pregnancies per 1000 woman years using contraceptives
10 accidental pregnancies per 100 woman years using contraceptives
3d
single
Pearl index is defined as the number of "failures of contraception(i.e, accidental pregnancies) per 100 woman-years of exposure (HWY)" Failure rate per HMY = Total accidental pregnancies X 1200 ----------------------------------- Total months of exposure Thus, on entering values given in question, we get 10 as answer. ...
Social & Preventive Medicine
JIPMER 2017
09a64b04-343b-4045-aee2-3c4047bbe373
Unfamiliarity of familiar things is seen in:
Deja vu
Jamais vu
Deja entendu
Deja pence
1b
single
Jamais vu refers to the feeling of unfamiliarity for familiar things. Deja vu refers to the feeling that an event which is being currently experienced has also happened in the past.
Psychiatry
Miscellaneous