text
stringlengths
1
1.05M
meta
dict
Introduction {#s1} ============ Self-generated sensory stimuli will typically share a common temporal register--their physical onset times will be closely correlated with the moment in time when the causative motor action is completed. For example, if we imagine the act of clicking our fingers together, completing the...
{ "pile_set_name": "PubMed Central" }
Introduction {#s1} ============ In the fasting state, gastrointestinal contractions show characteristic motor patterns, designated as the migrating motor contractions (MMC) ([@r1]). MMC consist of three phases called as phase I (motor quiescent period), phase II (irregular and low amplitude contraction period) and pha...
{ "pile_set_name": "PubMed Central" }
Established 25 years ago by a small group of collaborators, the Trauma Audit and Research Network (TARN) is now recognised as the UK\'s national clinical audit for traumatic injury and holds the largest trauma registry in Europe. Based at Salford Royal NHS Foundation Trust, TARN\'s role is to support hospitals by provi...
{ "pile_set_name": "PubMed Central" }
INTRODUCTION {#sec1-1} ============ Surgery is the preferred treatment method for lung cancer; however, fear of surgery, incomprehension of primary disease and concern about postoperative complications result in severe depression and anxiety.[@ref1],[@ref2] Though the influence mechanism of psychological factors on pr...
{ "pile_set_name": "PubMed Central" }
Advancements in statistical and computational methods have much to contribute to promoting new discoveries in psychology. In particular, as found in diverse disciplines as marketing, health care, and medicine, machine learning and big data offer similarly unique potential to inform, test, and advance our knowledge of m...
{ "pile_set_name": "PubMed Central" }
Introduction ============ Preventing type 2 diabetes is a public health priority in the United States ([@R1]). Prediabetes occurs when a person's blood glucose level is higher than normal (fasting blood glucose level of 100--125 mg/dL \[5.6 to 7.0 mmol/L\]), putting the person at increased risk for heart disease, stro...
{ "pile_set_name": "PubMed Central" }
Background ========== Attention-deficit/hyperactivity disorder (ADHD) is one of the most common behavioral disorders in children and adolescents. Its rate in community samples is variably reported. A study reported the rate of 5.29% \[[@B1]\]. Meanwhile, the rate of its screening symptoms is much higher, reaching up t...
{ "pile_set_name": "PubMed Central" }
{ "pile_set_name": "PubMed Central" }
Published: November 12, 2019 Introduction {#sec1} ============ Ubiquitination is one of the most versatile post-translational modifications, controlling a wide variety of cellular processes ([@bib32]). In most cases, the carboxy terminus of ubiquitin (Ub) is covalently linked to the ε-amino (a primary amine) group of...
{ "pile_set_name": "PubMed Central" }
**Suggested citation:** EFSA CONTAM Panel (EFSA Panel on Contaminants in the Food Chain) , Knutsen HK, Alexander J, Barregård L, Bignami M, Brüschweiler B, Ceccatelli S, Cottrill B, Dinovi M, Grasl‐Kraupp B, Hogstrand C, Hoogenboom LR, Nebbia CS, Oswald IP, Petersen A, Rose M, Roudot A‐C, Schwerdtle T, Vleminckx C, Vol...
{ "pile_set_name": "PubMed Central" }
Introduction {#s1} ============ People frequently compare themselves to others [@pone.0036742-Festinger1], [@pone.0036742-Summerville1]. For example, people compare their salary to their co-worker\'s salary [@pone.0036742-Sweeney1] and their physical fitness to that of professional athletes [@pone.0036742-Mussweiler1]...
{ "pile_set_name": "PubMed Central" }
INTRODUCTION ============ Plastic deformation of crystalline materials is controlled by the glide of dislocations. It is well known that dislocation glide is governed by the presence of other lattice defects ([@R1]). In the case of polycrystalline materials, which are used in most practical applications, dislocation g...
{ "pile_set_name": "PubMed Central" }
Background ========== The transcortical puncture of the ventricles is considered to be a simple neurosurgical procedure and is performed as one of the first procedures in neurosurgical training \[[@B1]\]. The ventricular catheter is considered as a lifelong functioning implant in the case of a shunting procedure; ther...
{ "pile_set_name": "PubMed Central" }
1. Introduction =============== In the last few decades due to exponential improvement in the herbal medicine field *Moringa oleifera* is popular in develop countries because it is obtained from the natural source and shows less adverse effects. Herbal drugs and their constituents play an important role in different m...
{ "pile_set_name": "PubMed Central" }
Introduction {#Sec1} ============ In order to understand the primary processes of photosynthesis, it is essential to have a detailed and an accurate information about the molecular architecture of the pigment system of the antenna and the reaction center complexes, as well as their (macro-)assemblies. The non-invasiv...
{ "pile_set_name": "PubMed Central" }
INTRODUCTION {#sec1-1} ============ With the advancement of dentistry and the growing interest in the developments of ideal materials to replace lost dental tissue, resin-based composites have been widely used to restore posterior teeth.\[[@ref1]\] Concerns about aesthetics, the content of mercury in amalgam restorati...
{ "pile_set_name": "PubMed Central" }
Introduction ============ *Salvia miltiorrhiza* Bunge (family Labiatae) is one of the traditional bulk medicinal materials. Its dried roots have been prescribed for the clinical treatment of many human diseases, such as irregular menstruation, cardiovascular and cerebrovascular diseases, and inflammation ([@B20]; [@B2...
{ "pile_set_name": "PubMed Central" }
We thank Masotti ([@B1]) for his interest and comment in this issue of *Diabetes* on our recently published article ([@B2]). In his letter, Masotti proposed, on the basis of our study findings and those from his own laboratory, that the glycolytic/gluconeogenic pathways may play an integral role in body weight regulati...
{ "pile_set_name": "PubMed Central" }
Our raw data are available via the URL/DOI below: URL: <https://figshare.com/s/b2c43d7229c9eb83a7d5> DOI: [10.6084/m9.figshare.5135005](https://doi.org/10.6084/m9.figshare.5135005). Introduction {#sec001} ============ A decline in kidney function due to chronic kidney disease (CKD) causes mineral disorders. It leads ...
{ "pile_set_name": "PubMed Central" }
Introduction ============ The central nervous system first appears in the human embryo at around the 3rd or 4th week after fertilization; development continues until roughly to 2 years of age. In rats, development occurs from the second week of pregnancy until the end of lactation. This phase is known as "the critical...
{ "pile_set_name": "PubMed Central" }
Introduction {#Sec1} ============ Cardiovascular disease (CVD) is a common comorbidity in breast cancer survivors \[[@CR1], [@CR2]\] and estimated to be responsible for many non-cancer-related mortalities \[[@CR1]\]. This is partly due to aging, yet also a consequence of received treatment. The cardiotoxicity of cance...
{ "pile_set_name": "PubMed Central" }
![](EDU-1311-2016.01.jpg)Maria R. Bonsignore is Head of the ERS Clinical Physiology, Sleep and Pulmonary Circulation Assembly, and an Associate Professor at DiBiMIS, University of Palermo, Palermo, Italy. She has a research interest in respiratory sleep medicine, with a focus on obstructive sleep apnoea. She is also in...
{ "pile_set_name": "PubMed Central" }
Introduction ============ Lymph node (LN) metastasis has important prognostic implications in patients with cancer.[@b1-cmar-10-1597] Recently, the number of negative LNs has also attracted attention for its prognostic value. It has been reported that an increased number of negative LNs was associated with longer surv...
{ "pile_set_name": "PubMed Central" }
Introduction {#s1} ============ The efficient survival of multicellular organisms requires physiological co-ordination between cells, tissues and various organs. This co-ordination is achieved through signaling pathways some of which evolved in parallel with multicellular complexity. Release of calcium (Ca^2+^) from i...
{ "pile_set_name": "PubMed Central" }
1. Introduction {#sec1} =============== Esophageal cancer is known to be associated with metachronous cancers in other organs, particularly head and neck cancer and gastric cancer \[[@B1]--[@B4]\]. Recently, the survival rate of esophageal cancer patients after esophagectomy has improved due to progress in surgical te...
{ "pile_set_name": "PubMed Central" }
Introduction {#s1} ============ Atelectasis is a highly prevalent pulmonary complication in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) and an important cause of postoperative hypoxemia. [@pone.0078643-Magnusson1]--[@pone.0078643-Lundstrom1] Pulmonary collapse occurs early after the induction...
{ "pile_set_name": "PubMed Central" }
Introduction {#Sec1} ============ The heart is composed of multiple cell types that can be broadly categorized into cardiomyocytes (CMs) and non-CMs. In turn, CMs can be identified as primarily contractile or conducting. Together, conducting CMs comprise the cardiac conduction system (CCS), which coordinates the elect...
{ "pile_set_name": "PubMed Central" }
Background ========== Gout is a true crystal deposition disease in which all clinical manifestations are considered to be directly attributable to the presence of monosodium urate (MSU) crystals. It is one of the most prevalent inflammatory arthropathies with a prevalence of approximately 1.4%, and is the most common ...
{ "pile_set_name": "PubMed Central" }
All relevant data are within the paper and its Supporting Information files. Introduction {#sec001} ============ Reactive oxygen species (ROS) including superoxide anion and hydrogen peroxide play diverse roles in biology. ROS can inflict severe oxidative damage to cellular components, but when carefully controlled, ...
{ "pile_set_name": "PubMed Central" }
Introduction {#S0001} ============ In Poland, the use of antibiotic growth stimulators was banned on 1 January 2006 due to increasing levels of microbial resistance to drugs \[[@CIT0001], [@CIT0002]\] and the immunosuppressive activity of selected antibiotics \[[@CIT0003]\]. The above increased the demand for natural ...
{ "pile_set_name": "PubMed Central" }
1. Introduction {#sec1-biomolecules-09-00401} =============== Acid-sensing ion channels (ASICs) are members of ligand-gated cation channels and belong to the degenerin/epithelial Na^+^ channel superfamily. Four genes (ACCN1--ACCN4) express six subunits (ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3, and ASIC4), four of which ...
{ "pile_set_name": "PubMed Central" }
Introduction {#Sec1} ============ Neuroendocrine neoplasms may arise in a number of organs and come from cells containing vasoactive substances within secretory granules located in the cytoplasm \[[@CR1]\]. Neuroendocrine tumors can be classified further into large cell neuroendocrine carcinoma (LCNEC), small cell lun...
{ "pile_set_name": "PubMed Central" }
1. Introduction =============== Tetrahydrofolate plays a central role in one-carbon metabolism involving DNA biosynthesis, and the biologically active cofactor forms are substrates for at least 15 relevant enzymes \[[@B1-molecules-17-05604],[@B2-molecules-17-05604],[@B3-molecules-17-05604],[@B4-molecules-17-05604]\]. ...
{ "pile_set_name": "PubMed Central" }
Data have been deposited to Figshare: (<http://dx.doi.org/10.6084/m9.figshare.1453184>). Introduction {#sec002} ============ Most drug users use more than one pharmacological class of drugs, and many develop dependence on several drugs \[[@pone.0140501.ref001]\]---these individuals are termed polydrug users. Polydrug...
{ "pile_set_name": "PubMed Central" }
Introduction ============ An increased mortality from lung cancer has been reported in workers from two beryllium facilities in the USA that were in operation in the 1940s ([@R7]; [@R16]; [@R17]). The increased risk was restricted to workers in these two facilities who were first employed before 1960, as workers hired...
{ "pile_set_name": "PubMed Central" }
(J Am Heart Assoc. 2019;8:e011160 DOI: 10.1161/JAHA.118.011160.)30834806 Clinical PerspectiveWhat Is New?Accurate prediction of adverse events after coronary revascularization is essential for preprocedural informed consent and for appropriate therapy selection.This study utilized novel machine learning methodologies ...
{ "pile_set_name": "PubMed Central" }
Main Text {#sec1} ========= Lung cancer remains one of the leading causes of deaths from cancer worldwide, with ∼80% of all cases presenting as non-small-cell lung cancer (NSCLC).[@bib1], [@bib2] Currently, the standard first-line treatment for patients with advanced NSCLC without targetable driver mutations is platin...
{ "pile_set_name": "PubMed Central" }
1. Introduction {#sec1-nutrients-11-02661} =============== Globally, human dietary patterns range substantially in the degree of inclusion vs. avoidance of animal-based foods. Vegetarianism refers to the exclusion of meat, fish, seafood and possibly other animal products such as dairy and eggs. In this review, in acco...
{ "pile_set_name": "PubMed Central" }
![](brjcancer00446-0133.tif "scanned-page"){.741} ![](brjcancer00446-0134.tif "scanned-page"){.742} ![](brjcancer00446-0135.tif "scanned-page"){.743} ![](brjcancer00446-0136.tif "scanned-page"){.744} ![](brjcancer00446-0137.tif "scanned-page"){.745}
{ "pile_set_name": "PubMed Central" }
Introduction {#Sec1} ============ Young African American men who have sex with men (AAMSM) are disproportionately impacted by new HIV infections and HIV-related mortality \[[@CR1]--[@CR5]\]. MSM account for more than three-fourths of all new HIV infections among men in the U.S. and nearly half of these are AAMSM \[[@C...
{ "pile_set_name": "PubMed Central" }
Rabbit haemorrhagic disease (RHD) is a highly contagious and often lethal viral infection of wild and domestic rabbits (*Oryctolagus cuniculus*), which first emerged in China in 1984 \[[@CR19]\]. Over the next years RHD spread throughout the world affecting many countries, mainly in Asia and Europe but also in Africa, ...
{ "pile_set_name": "PubMed Central" }
Introduction {#s1} ============ The use of mitochondrial DNA (mtDNA) as a marker for studying the demographic and evolutionary history of natural populations is widely established [@pone.0106267-Avise1]. Several characteristics of the genome make it especially suited to this purpose including its relatively rapid rate...
{ "pile_set_name": "PubMed Central" }
The human ether-à-go-go-related gene (hERG, Kv 11.1) channel has played an especially important role in cardiac safety and the hERG patch clamp assay is a key regulatory requirement before a first in man trial[@b1] (<http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM074963.pdf>). H...
{ "pile_set_name": "PubMed Central" }
{ "pile_set_name": "PubMed Central" }
![](indmedgaz71774-0069){#sp1 .194} ![](indmedgaz71774-0070){#sp2 .195}
{ "pile_set_name": "PubMed Central" }
Introduction {#Sec1} ============ Plasmodium gametocytes develop from their asexual progenitors and are the only malaria parasite life-stage infective to mosquitoes. In preparation for their development in the mosquito, gametocytes cease to express many proteins involved in the parasites cycle of asexual replication, ...
{ "pile_set_name": "PubMed Central" }
Background ========== Common mental disorders have a high prevalence in women, particularly at childbearing age \[[@B1]\]. It is increasingly recognised that many, if not the majority of cases of perinatal depression begin in the antenatal period and persist after childbirth \[[@B2]\]. Perinatal depression is a major ...
{ "pile_set_name": "PubMed Central" }
Jones JS, Milton F, Mostazir M, Adlam ALR. The academic outcomes of working memory and metacognitive strategy training in children: A double‐blind randomized controlled trial. Dev Sci. 2020;23:e12870 10.1111/desc.12870 31134713 Research HighlightsNinety‐five children were randomly allocated to receive working memory t...
{ "pile_set_name": "PubMed Central" }
**Potential link between preeclampsia (PE) and posterior cortical atrophy (PCA):** PCA is a neurodegenerative disorder affecting the parietal, occipital, and occipital-temporal brain regions, often manifesting as a decline in visual processing and perception skills in affected individuals. The most common underlying pa...
{ "pile_set_name": "PubMed Central" }
Background {#Sec1} ========== Decreased physical activity has been associated with the increased prevalence of childhood overweight and obesity in Canada \[[@CR1]\], the United States and across Europe \[[@CR2]\]. Physical activity is especially important during the early years of childhood, as it has been associated ...
{ "pile_set_name": "PubMed Central" }
![](envhper00373-0016-color.jpg "scanned-page"){.214}
{ "pile_set_name": "PubMed Central" }
![](indmedgaz72127-0031){#sp1 .91} ![](indmedgaz72127-0032){#sp2 .92}
{ "pile_set_name": "PubMed Central" }
Introduction {#sec1-1} ============ Domesticated Japanese quail (*Coturnix coturnix japonica*) is medium-sized fowl which more eaten by Egyptians due to its low cost, rapid growth, early onset of lay, high reproduction rates, and low feed intake. Japanese quail meat is high protein content (19.6%), low-fat content (12...
{ "pile_set_name": "PubMed Central" }
Introduction {#sec1} ============ Multilayer graphene (MLG) is expected to be applied to low-resistance wiring, heat spreaders, and anodes for lithium-ion batteries because of its high electrical/thermal conductivities, current-carrying capacity, and specific capacity.^[@ref1]−[@ref4]^ To make use of these features, i...
{ "pile_set_name": "PubMed Central" }
Introduction ============ The performance of voluntary motor tasks is associated with the primary motor cortex of the brain ([@b1-etm-0-0-2788]). Furthermore, cerebral blood flow and glucose metabolism have been demonstrated to positively correlate with neuronal processes during neuronal transmission in a healthy brai...
{ "pile_set_name": "PubMed Central" }
Introduction {#Sec1} ============ Near Infrared Spectroscopy (NIRS) is a non-invasive optical technique allowing a continuous measurement of brain\'s hemoglobin saturation in oxygen (rSO2). It is considered as a surrogate marker of cerebral insult, and recognized as a useful tool in in cardiovascular surgery and neuro...
{ "pile_set_name": "PubMed Central" }
![Insight from Mark Levis](JEM_20171056_Fig1){#fig1} Defining and characterizing the hematopoietic stem cell (HSC) has been an endeavor that has occupied more than one generation of experimental hematologists. An ongoing challenge has been to reconcile a functional definition of the HSC, encompassing the properties of...
{ "pile_set_name": "PubMed Central" }
Background ========== Within many healthcare systems, there has been a growing focus on the value of telehealth and telecare interventions for improving quality and cost-effectiveness of care for people with long term complex health and social care needs \[[@B1]\]. Such technologies are varied, but a distinction is ge...
{ "pile_set_name": "PubMed Central" }
INTRODUCTION ============ Anemia is the most common complication of inflammatory bowel disease (IBD)^[@R1],[@R2]^ both at diagnosis and during flare-ups,^[@R3],[@R4]^ exceeding by far the frequency of extraintestinal manifestations (eg, rheumatic, dermatologic, and ophthalmologic).^[@R5],[@R6]^ Thus, in a systematic r...
{ "pile_set_name": "PubMed Central" }
Introduction ============ Myasthenia gravis (MG) is a chronic autoimmune neuromuscular disease manifesting with weakness and fatigue of skeletal muscles after physical exercise, with a tendency to subside after periods of rest and typically after taking anticholinesterase medication. Myasthenia gravis is characterized...
{ "pile_set_name": "PubMed Central" }
Background {#Sec1} ========== Workers in high-intensity livestock operations have been recognized to be at risk for a number of chronic respiratory problems including bronchitis, rhinitis, chronic cough and phlegm, occupational asthma, and organic dust toxic syndrome to name a few \[[@CR1]--[@CR3]\]. Workers in such f...
{ "pile_set_name": "PubMed Central" }
![](edinbmedsurgj72466-0068){#sp1 .62} ![](edinbmedsurgj72466-0069){#sp2 .63} ![](edinbmedsurgj72466-0070){#sp3 .64} ![](edinbmedsurgj72466-0071){#sp4 .65} ![](edinbmedsurgj72466-0072){#sp5 .66} ![](edinbmedsurgj72466-0073){#sp6 .67} ![](edinbmedsurgj72466-0074){#sp7 .68} ![](edinbmedsurgj72466-0075){#sp8 .69} ...
{ "pile_set_name": "PubMed Central" }
Ovarian cancer is a highly lethal gynecological malignancy because it is almost always diagnosed at a late stage \[[@bb0005],[@bb0010]\]. Despite the best efforts of researchers and clinicians alike, survival rates for women diagnosed with this devastating disease have improved by only 8.5% in the last twenty years sin...
{ "pile_set_name": "PubMed Central" }
**Specifications Table**TableSubject areaChemistry, Biology, and material scienceMore specific subject areaGreen synthesis of Ag/Fe~3~O~4~ nanocomposite by using starchType of dataFiguresHow data was acquiredUV--visible absorption spectra of samples were obtained by a double beam UV--visible spectrophotometer (Cary 100...
{ "pile_set_name": "PubMed Central" }
Background {#Sec1} ========== Recent studies have shown that alcohol and illicit drug use is prevalent among secondary school students in Botswana. In 2005, the WHO-developed Global School-based Health Survey (GSHS) showed that 20.9% of surveyed 13- to 15-year-old secondary school students in Botswana "drank so much a...
{ "pile_set_name": "PubMed Central" }
CLINICAL FEATURES {#sec1-1} ================= Systemic lupus erythematosus (SLE) is a multi-systemic disease. The clinical findings depend on the severity and extent of the disease. Most patients initially present with fatigue and fever; the latter may be of low grade or show periods of spiking. Weight loss may also o...
{ "pile_set_name": "PubMed Central" }
1. Introduction {#sec1} =============== Diarrhea disease is one of major threats that afflict the global pork industry in recent years, which has caused an estimated loss of multi-million dollar annually. Various pathogens that can cause diarrhea in swine have been identified, and swine enteric coronaviruses are the m...
{ "pile_set_name": "PubMed Central" }
Introduction/Background {#Sec1} ======================= Dry needling (DN) is a subcutaneous needle insertion technique using a fine, solid needle without anesthetic or injection \[[@CR1]\]. DN can be distinguished from acupuncture, which although applied with a solid filiform needle, uses Traditional Chinese Medicine ...
{ "pile_set_name": "PubMed Central" }
Background ========== Prostate cancer (PCa) is the second most common cancer, and the fifth leading cause of cancer related death among men worldwide. Immunotherapy designed to induce tumor cell specific immune responses capable of destroying tumor cells has emerged as a promising treatment modality in solid malignant...
{ "pile_set_name": "PubMed Central" }
All relevant data are within the paper and its Supporting Information files. Introduction {#sec001} ============ Vagus nerve stimulation (VNS) is an approved clinical therapy for medically refractory epilepsy and depression \[[@pone.0163734.ref001]--[@pone.0163734.ref003]\]. More recently, VNS has been proposed as a ...
{ "pile_set_name": "PubMed Central" }
1. Introduction =============== Risk assessment for invasive weeds has focused primarily on assessing the risk of new species invading and/or establishing in previously uncolonized locations \[[@b1-ijerph-08-02828]--[@b4-ijerph-08-02828]\]. Although this approach is an important predictive tool in global efforts to pr...
{ "pile_set_name": "PubMed Central" }
Data for all experiments conducted for this paper will be made publicly available on the Oxford University Research Archive. The doi is [10.5287/bodleian:NGYZrDjOq](https://doi.org/10.5287/bodleian:NGYZrDjOq). Introduction {#sec001} ============ Aggression towards conspecifics is prevalent throughout the animal kingd...
{ "pile_set_name": "PubMed Central" }
1. Introduction {#sec1} =============== *Mycobacterium chelonae* is an atypical mycobacterium which does not cause tuberculosis or leprosy in humans. They are known for infections of skin, lungs, eyes, and soft tissue. People with immunodeficiency are more likely to contract an infection although a minority of concern...
{ "pile_set_name": "PubMed Central" }
INTRODUCTION ============ Age-dependent decline in muscle mass and strength is one of the remarkable public health concerns due to its adverse consequences including functional limitations and disabilities, increased risk of falls in older people, morbidities and all-cause mortality \[[@B1][@B2]\]. Some related factor...
{ "pile_set_name": "PubMed Central" }
Introduction {#S1} ============ Despite recent technical advances, the mortality of patients undergoing hemodialysis (HD) continues to be very high. In Spain, annual mortality is 15%, ranging from 3% in patients younger than 45 years to 24% in patients older than 75 years ([@B1]--[@B3]). Our country ranks middle in th...
{ "pile_set_name": "PubMed Central" }
![](edinbmedsurgj72607-0007){#sp1 .i} ![](edinbmedsurgj72607-0008){#sp2 .ii} ![](edinbmedsurgj72607-0009){#sp3 .iii} ![](edinbmedsurgj72607-0010){#sp4 .iv} ![](edinbmedsurgj72607-0011){#sp5 .v} ![](edinbmedsurgj72607-0012){#sp6 .vi} ![](edinbmedsurgj72607-0013){#sp7 .vii} ![](edinbmedsurgj72607-0014){#sp8 .viii}...
{ "pile_set_name": "PubMed Central" }
![](menthealthlond70775-0039){#sp1 .77} ![](menthealthlond70775-0040){#sp2 .78} ![](menthealthlond70775-0041){#sp3 .79} ![](menthealthlond70775-0042){#sp4 .80}
{ "pile_set_name": "PubMed Central" }
**Note** please consult PDF for full article
{ "pile_set_name": "PubMed Central" }
(To access the full article, please see PDF)
{ "pile_set_name": "PubMed Central" }
1. INTRODUCTION =============== Infection of the respiratory tract is regarded as the most common infection among humans worldwide \[[@r1]\]. Respiratory infections are a persistent health problem and being a common reason for consultation and hospitalization, impose an enormous burden on society. The clinical feature...
{ "pile_set_name": "PubMed Central" }
INTRODUCTION ============ The direct visualization of specific sites on DNA molecules of many hundreds of kilobases in length can provide valuable genomic information, which often complements that derived from sequencing. For example, fluorescence *in situ* hybridization is often used to study structural variations wi...
{ "pile_set_name": "PubMed Central" }
Although the geographic extent of endemic malaria transmission has been curtailed during the last century---in part through intensive mosquito control programs---the World Health Organization estimates that approximately 660,000 deaths were attributable to malaria in 2010 ([@bib11]). The importance of mosquitoes to mal...
{ "pile_set_name": "PubMed Central" }
Introduction {#Sec1} ============ High-resolution X-ray fiber diffraction is a key method for determining the structures of helical filaments that resist conventional crystallization^[@CR1],\ [@CR2]^. Helical structures consist of identical subunits, which repeat after a defined number of turns along the fiber axis. T...
{ "pile_set_name": "PubMed Central" }
Introduction {#sec1-1} ============ The incidence of clinically apparent thyroid swellings in the general population is 4%--5%.\[[@ref1]\] Majority of these swellings are benign in nature, among which goiter being most common. The prevalence of goiter is more than 40 million in India with more than 2 billion globally....
{ "pile_set_name": "PubMed Central" }
1. Introduction {#sec0005} =============== Epidermoid cyst in the floor of the mouth is an uncommon developmental lesion. The pathogenesis is the entrapment of the ectodermal tissue along embryonic fusion lines. The clinical presentation is a progressive swelling in the floor of the mouth and neck. If large enough, th...
{ "pile_set_name": "PubMed Central" }
Introduction {#S1} ============ With the development of industrialization and urbanization, the abundance of heavy metals in the environment has increased enormously during the past decades, which raised significant concerns throughout the world ([@B142]; [@B7]). Heavy metals are a group of metallic chemical elements ...
{ "pile_set_name": "PubMed Central" }
Introduction {#s1} ============ Infection with HIV initiates a series of events that ultimately lead to profound immunosuppression, caused by functional abnormalities in the immune system, mainly due to severe depletion of CD4^+^ T cells [@pone.0057336-Moir1]. The introduction of HAART has led to very important decli...
{ "pile_set_name": "PubMed Central" }
Revised. Amendments from Version 1 ================================== Based on the reviews received we corrected some typographical errors, added some useful additional references, revised a few sentences for clarity and emphasised the importance of education to support rabies control programmes and ensure their susta...
{ "pile_set_name": "PubMed Central" }
1. Introduction {#sec1} =============== Bronchogenic cysts are congenital lesions arising from abnormal budding of the embryonic foregut, during early embryogenesis. They develop most commonly in the mediastinum, posterior to the carina \[[@B1]\]. Retroperitoneal location is extremely rare \[[@B2]\]. We report a case ...
{ "pile_set_name": "PubMed Central" }
Since the introduction of continuous ambulatory peritoneal dialysis by Moncrief and Popovich in 1976, the number of patients treated with peritoneal dialysis has continuously increased. Today, approximately 200 000 patients are treated with peritoneal dialysis (PD), and the growth is particularly rapid in many Asian co...
{ "pile_set_name": "PubMed Central" }
Introduction {#sec1-1} ============ Lymphedema is a chronic localised swelling caused due to excessive accumulation of lymphatic fluid in the interstitium and resulting from defective lymphatic drainage \[[@ref1]\]. Lymphedema can be primary or secondary. Primary lymphedema results from developmental abnormalities lea...
{ "pile_set_name": "PubMed Central" }
Historically, *Mycobacterium bovis* infection in humans was associated with consumption of unpasteurized milk and dairy products ([@R1],[@R2]) and this is still the most important route of exposure in developing countries. US populations are exposed to unpasteurized dairy products imported from countries where *M. bovi...
{ "pile_set_name": "PubMed Central" }
Ataxia with oculomotor apraxia type 4 (AOA4) is an autosomal recessive (AR) disorder recently delineated in a Portuguese cohort and caused by mutations in the *PNKP* (polynucleotide kinase 3′-phosphatase) gene.^[@R1]^ AOA4 is a progressive, complex movement disorder that includes hyperkinetic features, eye movement abn...
{ "pile_set_name": "PubMed Central" }
Within reason the patient\'s age and the number, site or size of fibroids should not be an impediment to uterus-preserving surgery with a view to future conception. Case report 1 {#s2} ============= This 45-year-old woman was a tertiary referral to our Myoma Service with a diagnosis of symptomatic fibroids confirmed ...
{ "pile_set_name": "PubMed Central" }
The intimal lining of synovial tissue consists of fibroblast-like synoviocytes (type A synoviocytes) and macrophages (type B synoviocytes). These cells are able to interact through the CD97/CD55 receptor ligand system. The CD97 receptor is a heterodimer receptor composed of an alpha and a beta subunit. The CD97alpha su...
{ "pile_set_name": "PubMed Central" }
Introduction {#s1} ============ Ultraviolet (UV) light is a pervasive environmental exposure with pleotropic effects on the skin. Sensitivity to UV light is a shared feature of several autoimmune diseases, including systemic and cutaneous lupus erythematosus (SLE and CLE, respectively), dermatomyositis, and occasional...
{ "pile_set_name": "PubMed Central" }
{ "pile_set_name": "PubMed Central" }
Currently, ER*α* expression is regarded as a reliable prognostic marker with which to predict the response of an individual breast cancer to hormone therapy ([Pertschuk and Axiotis, 1999](#bib16){ref-type="other"}). However, up to 40% of breast tumours with positive ER*α* status do not respond to endocrine manipulation...
{ "pile_set_name": "PubMed Central" }
Introduction {#s1} ============ Recent clinical studies have demonstrated that the blood concentration of cardiac troponin T (high-sensitivity cardiac troponin T (hs-cTnT)) can be measured by a highly sensitive assay. The blood concentration of hs-cTnT is a useful biomarker to evaluate myocardial injury or to predict ...
{ "pile_set_name": "PubMed Central" }
Critical thinking in nursing is complex and described by a mosaic of different definitions. These various definitions have led to confusion about what critical thinking entails \[[@R1]\]. In nursing education, critical thinking is a key objective and/or desired outcome for almost every nursing course and is an aspect o...
{ "pile_set_name": "PubMed Central" }