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Tariq S. Hakky, MD
Department of Urology
University of Southern Florida, USA
Moffitt Cancer Center, USA
E-mail: tariq7\@gmail.com
| {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Philadelphia-negative myeloproliferative neoplasms (MPNs) are a spectrum of clonal disorders of the hematopoietic system characterized by overproduction of mature blood elements, a trend to thrombotic and/or hemorrhagic complications with variable rates of transformation to seco... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-polymers-12-00045}
===============
Carbon-fiber-reinforced polymer composites have attracted scientific attention from many groups aiming for scientific research and industrial utilization, and are widely used as novel engineering materials in many fields because of their high tensile strength, ... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Crohn\'s disease (CD) is defined as the immune-mediated chronic intestinal disorder characterized by non-caseating granuloma and transmural inflammation of unknown etiology.[@B1] Although it may develop anywhere in the gastrointestinal tract, from the mouth to the anus, the most frequent pres... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Aromatic polyesters are widely used indispensable plastics currently produced from petroleum^[@CR1]^. Microbial fermentative production of polymers from renewable resources has received much attention to substitute petroleum-based polymers and help solving environmental problems. Thus... | {
"pile_set_name": "PubMed Central"
} |
Mitochondria contain their own genome--a maternally-inherited 16.6 kb circular double-stranded DNA molecule (mtDNA) encoding 13 proteins, 22 mt-tRNAs and two mt-rRNAs. Each mitochondrion harbours multiple copies of mtDNA and each cell contains multiple mitochondria. Point mutations and large-scale rearrangements (delet... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Research into errors occurring during skilled human behavior has a long tradition, and has revealed important insights into planning and execution of complex tasks, such as speech, typing, and music performance (for the music domain, see e.g., Palmer and van de Sande, [@B51], [@B52]; Pa... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Open and endovascular repair of thoracoabdominal aortic aneurysms (TAAAs) is associated with a high risk of complications such as acute kidney injury^[@CR1],[@CR2]^. Moreover, postoperative AKI is related to increased mortality rates after open, endovascular and emergency aortic aneur... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
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Introduction
============
The genetic code is essential to all forms of life and is of fundamental importance to the whole of biology. Until relatively recently, the code was thought to be invariable, frozen, in all organisms, because of the way in which any change would produce widespread alteration in the amino acid... | {
"pile_set_name": "PubMed Central"
} |
In the article titled "Fetal cardiac arrhythmias: Current evidence", published on pages 148-163, Issue 2, Volume 11 of Annals of Pediatric Cardiology,\[[@ref1]\] the name of the author Edward Araujo Junior is written incorrectly as "Junior EA" instead of "Araujo Júnior E".
The "How to cite this article" section should... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Stem rust (caused by *Puccinia graminis* f. sp. *tritici* Erikss. & E. Henn.) is one of the most damaging diseases in wheat ([@B30]). It occurred frequently in the United States from the 1920s to 1960s and caused up to 50% yield losses ([@B18]). In the central United States Great Plains, an a... | {
"pile_set_name": "PubMed Central"
} |
Past {#Sec1}
====
Twenty years' experience in practicing sentinel lymph node biopsy (SLNB) in breast cancer patients demonstrates that residual axillary tumor burden is not synonymous with disease recurrence over time. While meta-analyses have reported a false-negative rate (FNR) for SLNB between 5 and 7%, the reporte... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#Sec1}
===============
Fidaxomicin is an oral, narrow-spectrum antibacterial that is being developed by Optimer Pharmaceuticals for the treatment of *Clostridium difficile* infections. The compound was previously being jointly developed by Optimer and Par Pharmaceuticals; the latter had exclusive righ... | {
"pile_set_name": "PubMed Central"
} |
{#Fa}
Here is a clue: He died in a self-experiment that showed that verruga peruana and Oroya fever are etiologically related.
Who is he?
==========
1. Albert Barton
2. Daniel Alcides Carrión
3. Max Kuczynski-Godard
4. Ernest Odriozola
5. Garcilasco de la Vega
![This is a phot... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Animals have to ingest and digest food to ensure the continuous functioning of their internal metabolism by covering, for example, their energy, protein and vitamin requirements [@pone.0072770-Robbins1]. The multi-stage process of digestion includes mechanical, chemical and enzymatic st... | {
"pile_set_name": "PubMed Central"
} |
Dear editor,
Lung cancer is the leading cause of cancer-related death worldwide, with the predominant pathological type being non-small cell lung cancer (NSCLC) \[[@CR1], [@CR2]\]. Next-generation sequencing (NGS) analysis is increasingly used to help clinicians select appropriate target therapies, such as epidermal g... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s0}
============
*Candida albicans* is a normal commensal of humans that can become a potentially life-threatening fungal pathogen in immunosuppressed patients. Systemic infections resulting from *C. albicans* are associated with mortality rates of 50% or greater despite currently available antifungal t... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S1}
============
Basic functional tasks require the coordination and cooperation of neurons distributed in multiple regions across the brain, all of which are in a state of rapid growth in pre-adult populations. Researchers focused on pre-adult populations face considerable challenges due to brain activ... | {
"pile_set_name": "PubMed Central"
} |
Obara K, Abe E, Shimozawa N, Toyoshima I. A case of female adrenoleukodystrophy carrier with insidious neurogenic bladder. J Gen Fam Med. 2020;21:146--147. 10.1002/jgf2.314
1. INTRODUCTION {#jgf2314-sec-0001}
===============
Adrenoleukodystrophy (ALD) is an X‐linked hereditary disease caused by mutations in the ABCD1... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
Emphysematous pyelonephritis (EPN) is a rare disease. A history of diabetes mellitus and female gender are common predisposing factors.\[[@ref1][@ref2][@ref3]\] In comparison with simple pyelonephritis, EPN is an acute severe necrotizing infection of the renal parenchyma, and is a l... | {
"pile_set_name": "PubMed Central"
} |
Essential in the metabolism of all living organisms, the enzymes are increasingly used to drive chemical reactions outside their natural localization. In particular, the use of the biocatalysts as food additives and in processing raw materials has been practiced for a long time. In fact, enzymatic preparations from the... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-nanomaterials-10-00519}
===============
Surface-enhanced Raman spectroscopy (SERS) is a surface-sensitive technique that amplifies the Raman scattering intensities through molecules adsorbed on rough metal surfaces or nanostructured films subjected to light irradiation \[[@B1-nanomaterials-10-00... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
Postoperative nausea and vomiting (PONV) are common and distressing symptoms after surgery performed under general anaesthesia, with an incidence as high as 60%.\[[@ref1]\] Female patients experience PONV more often and it is more severe than that experienced by male patients.\[[@re... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Rotavirus (RV) is the most common cause of viral gastroenteritis in children, and 43--78% of asymptomatic neonatal infections have been described \[[@CR1]\]. Despite being predominantly asymptomatic, neonatal RV infection has received considerable attention, because some studies have repo... | {
"pile_set_name": "PubMed Central"
} |
An excess of proteinase receptors in the brain aggravates demyelination in multiple sclerosis (MS), suggest Noorbakhsh and colleagues on page 425. Mice lacking proteinase-activated receptor-2 (PAR~2~), they show, are protected from the brain damage characteristic of experimental autoimmune encephalomyelitis (EAE), a mo... | {
"pile_set_name": "PubMed Central"
} |
Due to the ethical considerations, data are available upon request. Data are from the "Developing the Observatory Test of Capacity, Performance, and Developmental Disregard (OTCPDD) for Children with Cerebral Palsy" study whose authors may be contacted at <tnwang@ntu.edu.tw>.
Introduction {#sec005}
============
Cereb... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Learning methods have been continually changing over time with the increasing employment of learning technology^[@CR1]--[@CR3]^. The ease and access of mobile platforms and the internet have provided new methods of communication and teaching. Following this trend, the use of three-dim... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
**Objective:** This aim of the present study was to determine the demographic and clinical characteristic of suicide attempts in adolescents compared than those of adults.
**Methods:** The subjects were suicide attempters visited in emergency department at a university hospital. We prospectively collected data on soci... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Perilipins are phosphorylated proteins in adipocytes localized at the surface of the lipid droplet in adipocytes, steroid-producing cells and ruptured atherosclerotic plaques \[[@B1]-[@B4]\]. These proteins are essential in the regulation of triglyceride deposition and mobilization \[[@B5]-[@B7]\... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
Coronavirus disease 2019 (COVID-19) now affects 210 countries and all 6 World Health Organization regions to date.^[@bib1]^ COVID-19 represents a multisystem disease caused by the novel coronavirus strain severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which was first detected in Wuhan, China, in December... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Defective beta-cell function is one of the key reasons underlying the pathological process of both type 1 and 2 diabetes mellitus. Normal insulin-producing pancreatic beta-cells possess the powerful ability of adaptation and proliferation in response to chronic metabolic challenges such... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Glioblastoma multiforme (GBM) is the most common and deadly primary malignant tumor of the central nervous system in humans. The prognosis of GBM is bleak. Median survival is 15--23 months ([@B1]), which is in part due to several biological properties rendering the tumor type particular... | {
"pile_set_name": "PubMed Central"
} |
Several multi-targeted vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors (TKI) have been approved by the US FDA including sunitinib, sorafenib, pazopanib, axitinib, vandetanib, cabozantinib, ponatinib and regorafenib. However, these agents may also target kinases that are essential for card... | {
"pile_set_name": "PubMed Central"
} |
Sir,
Paracetamol (acetaminophen) is the most extensively used over-the-counter analgesic and antipyretic agent. Over dosing of paracetamol can lead to hospital admissions.\[[@ref1][@ref2]\] In the United Kingdom, nearly 50% of drug poisoning occurs due to paracetamol over dosing and nearly 100-200 people die every yea... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the manuscript.
Introduction {#sec001}
============
Hyperthermia (HT) therapy, defined as the moderate elevation of body tissues to temperatures of 39--45°C, has been used as a compelling treatment of cancers for centuries \[[@pone.0237372.ref001]\]. The hindrance to its adoption into reg... | {
"pile_set_name": "PubMed Central"
} |
Introduction, Methods and Results
=================================
Scrapie is a prion disease that affects sheep and goats. It belongs to the group of transmissible spongiform encephalopathies (TSE) that also comprises the zoonotic bovine spongiform encephalopathy (BSE). Major determinants for sheep scrapie occurrenc... | {
"pile_set_name": "PubMed Central"
} |
The second author's name is spelled incorrectly. The correct name is: Claudine J. C. Lamoth. The publisher apologizes for the error.
| {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
============
Although advances have been made in the treatment strategies and management of patients with acute myocardial infarction (AMI), some patients still have poor outcomes \[[@R1]--[@R4]\]. Early risk stratification is important for such patients. Patients found to be at high risk by early r... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
*Boswellia papyrifera* and *Boswellia carterii*, commonly known as Arabian incense, are traditionally used in the Ayurvedic system of medicine to treat arthritis. The chemical compositions of these plants were well characterized and reportedly include isoincensole and incensole acetate ... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and its Supporting Information files.
1. Introduction {#sec005}
===============
Neurosurgery provides highly specialised treatments to patients. While the number of patients treated is small compared to other medical disciplines, it is steadily growing with the aging of the popu... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s01}
============
Inflammation is a crucial host response against internal and external insults. The innate immune sentinels, pattern recognition receptors (PRRs), survey the presence of exogenous invariant microbial motifs, known as pathogen-associated molecular patterns, and endogenous danger signals ... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-ijerph-16-00219}
===============
Due to the enormous influences (over 1.2 million fatalities, as many as 50 million injuries, and billions of dollars in medical treatment and productivity loss annually) of roadway crashes on human societies, reducing crash risk has long been a primary objective ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S0001}
============
The Gram-positive coccal bacterium *Staphylococcus aureus* is a common member of the human microbiota, as well as a leading cause of bacterial infections in both hospital and community settings.^[1](#CIT0001),[2](#CIT0002)^ While *S. aureus* infections are usually localized to the sk... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Although the majority of children with newly diagnosed cancer are expected to be long-term survivors, cure remains elusive for patients with certain tumor types. For example, patients with high-risk neuroblastoma, advanced sarcoma, or high-grade glioma who relapse after initial therapy are ra... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
The cattle tick, *Rhipicephalus (Boophilus) microplus*, is distributed in tropical and subtropical regions of the world \[[@B1]\]. Infestations with *R. microplus*economically impact cattle industry by reducing weight gain and milk production, and by transmitting pathogens that cause babesiosis (... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Studies of wild-type or genetically engineered mice maintained under germ-free conditions, or colonized with microbes derived from healthy or diseased humans (or other species), have been instrumental in advancing understanding of the assembly, dynamic operations, functional properties, a... | {
"pile_set_name": "PubMed Central"
} |
Citation
========
Luz FA, Gonçalves GL, Moreira GRP, Becker VO (2014) Three new cecidogenous species of *Palaeomystella* Fletcher (Lepidoptera, Momphidae) from the Brazilian Atlantic Rain Forest. ZooKeys 433: 97--127. doi: [10.3897/zookeys.433.7379](10.3897/zookeys.433.7379)
Introduction
============
Cecidogeny has ... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
*Siniperca chuatsi* rhabdovirus (SCRV), as one of the piscine rhabdoviruses, has caused great losses to the Chinese perch aquaculture industry \[[@bib1],[@bib2]\]. The viral genome is a negative single-stranded RNA with the length about 11 kb, which encodes five structural prote... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1-1}
============
Spinal deformity is a condition that has been recognized for many millennia,^[@ref1]^ with documented attempts at scoliosis correction dating back at least 5000 years.^[@ref2]^ Our understanding of the development and progression of spinal deformity has increased significantly in re... | {
"pile_set_name": "PubMed Central"
} |
Karlsson SA, Hero C, Eliasson B, et al. Refill adherence and persistence to lipid‐lowering medicines in patients with type 2 diabetes: A nation‐wide register‐based study. Pharmacoepidemiol Drug Saf. 2017;26:1220--1232. <https://doi.org/10.1002/pds.4281> 28799214
Statement about prior postings and presentations: Result... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
The understanding of the structure, function and interactions of biomolecules has greatly advanced through spectroscopic methods^[@CR1]--[@CR4]^. In this context a particularly widely applicable approach is vibrational spectroscopy, which represents a sensitive analytical and label-fr... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#s0005}
===============
There is considerable evidence that physical activity participation during pregnancy has beneficial effects for both the mother and fetus ([@bb0035], [@bb0105]). For the mother, physical activity may help prevent gestational diabetes, pre-eclampsia, support healthy weight, and ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Schizophrenia is a severe and complex disorder, not only characterized by delusions and hallucinations, but also by abnormalities in the processing of emotions [@pone.0099667-Phillips1], [@pone.0099667-Aleman1]. Literature suggests that the ability to regulate emotional stimuli is of gr... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Antihistaminergic drugs are commonly classified into three generations. First generation antihistamines, such as diphenhydramine, effectively block the H~1~receptor subtype but their use is limited due to significant central (sedation) and peripheral (tachycardia, xerostomia) antimuscarinic side ... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
The anterior cingulate cortex (ACC) is important for the affective and emotional component of physiological and pathological pain \[[@B1]-[@B5]\]. Brain imaging and electrophysiological studies have shown that the ACC responds to painful stimuli in humans \[[@B4],[@B6],[@B7]\] and nociceptive sti... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
In patients with cardiovascular diseases, the capacity of the organism to develop new blood vessels (neovascularization) constitutes an important adaptive mechanism against ischemia [@pone.0023308-Losordo1]. Recent studies suggest that postnatal neovascularization relies not exclusively... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new virus recently isolated from humans. This new virus is a betacoronavirus that belongs to the orthocoronavirinae subfamily of the coronaviridae family \[[@CR1], [@CR2]\]. SARS-CoV-2 was discovered to be the pathogen ... | {
"pile_set_name": "PubMed Central"
} |
**Specifications Table**TableSubject areaAir pollutionMore specific subject areaAerosol loading and Retention,aerosol size and aerosol optical depth statisticsType of dataTable and figureHow data was acquiredMulti-angle Imaging Spectro-Radiometer (MISR).Data formatRaw and analyzedExperimental factorsData retrieval of A... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Biological circuits in which a single input differentially regulates multiple outputs are beneficial in both naturally occurring and synthetically constructed contexts as they enable a common stimulus to drive multiple downstream effects. Often distinct output pathways must be activat... | {
"pile_set_name": "PubMed Central"
} |
In Table 1 of the above-mentioned article, the *ST6GAL1* locus was erroneously mislabeled as *ST64GAL1*.
The authors apologize for this error. The online version of the article (<https://doi.org/10.2337/db13-1663>) has been updated to correct this omission.
| {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the manuscript and its Supporting Information files.
Introduction {#sec005}
============
Atrial fibrillation (AF) is a common and complicated cardiac arrhythmia characterized by rapid and irregular atrial activation \[[@pone.0228405.ref001]--[@pone.0228405.ref003]\], which has a prevalenc... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Presence of autoantibodies (AAbs) specific against antigens present in the retina is the hallmark of autoimmune process in cancer-associated retinopathy (CAR) and autoimmune retinopathy (AR) \[[@CR1], [@CR2]\]. Patients diagnosed with paraneoplastic or non-paraneoplastic retinopathy o... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
The cross-national patterns of suicide rates, which can be influenced by gender and other factors, differ. Nevertheless, suicide rates generally increase with age. Since 1987, when China's suicide mortality statistics initially became available from the Ministry of Health, suicide rates i... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Low-vitamin D intakes or circulating levels have been associated with increased breast cancer risk in several ecological ([@bib15], [@bib16], [@bib19], [@bib20]), case--control and cohort studies ([@bib48], [@bib52], [@bib32], [@bib40], [@bib30], [@bib44], [@bib1]) although not all ([@bib18],... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Obesity is a complex disease caused by the interplay of genetics, epigenetics, and environmental factors. Different approaches such as linkage analysis, genome-wide association studies and exon as well as whole genome sequencing approaches identified numerous genes participating to th... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Energy storage devices including fuel cell, Li-batteries etc. have been developing especially today \[[@B1],[@B2]\]. Direct formic acid fuel cell has been receiving much attention as one of the most attractive energy sources \[[@B3]\]. Palladium (Pd) was found to show superior catalytic activ... | {
"pile_set_name": "PubMed Central"
} |
Sir,
Infantile hemangiomas are the most common childhood tumors.\[[@ref1]\] More than 50% of them occur in the head and neck region.\[[@ref1]\] As spontaneous regression occurs over years, active intervention is needed only for large complicated hemangiomas. But, even small uncomplicated hemangiomas in visibly promine... | {
"pile_set_name": "PubMed Central"
} |
Dear Editor-in-Chief
====================
Cancer is one of the most prevalent diseases in the world. More than 360,000 childhood cancer survivors live in the United States ([@B1]). In Korea, 89.4 children per 100,000 in the 0--14 age group suffer from some form of cancer ([@B2]). Physical activity is a well-known inte... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#s0005}
===============
As research accumulates on the deleterious health effects of prolonged sedentary behaviour, there is a growing need to understand the correlates of the behaviours typically associated with long periods of sedentary time. We define sedentary behaviour as being: "distinct from la... | {
"pile_set_name": "PubMed Central"
} |
Darabzadeh N, Hamidi‐Esfahani Z, Hejazi P. Optimization of cellulase production under solid‐state fermentation by a new mutant strain of *Trichoderma reesei*. Food Sci Nutr. 2019;7:572--578. 10.1002/fsn3.852
1. INTRODUCTION {#fsn3852-sec-0001}
===============
Cellulase, as a complex enzyme containing endoglucanase, e... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
DNA damage induces a G2 phase cell-cycle arrest in most tumour cell lines that lack functional p53 protein. Following abrogation of the G2 checkpoint, these cells arrest in mitosis and can subsequently form polyploid cells. This response is thought to represent an alternative to immediate death t... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-ijms-20-04405}
===============
There are approximately 5000--8000 rare diseases or conditions that affect 6--8% of the population \[Regulation EC No. 141/2000, 2000\]. Patients with these conditions are often isolated and experience significant obstacles in accessing high quality healthcare and ... | {
"pile_set_name": "PubMed Central"
} |
**Session:** 256. HAI: Miscellaneous
*Saturday, October 5, 2019: 12:15 PM*
| {
"pile_set_name": "PubMed Central"
} |
Background
==========
Following the London Declaration on Neglected Tropical Diseases, Human African Trypanosomiasis (HAT) has been targeted for elimination by 2020 \[[@B1]\]. As *Trypanosoma brucei gambiense* infection actually causes 98% of the total HAT cases (the remaining are due to *T. b. rhodesiense*), attentio... | {
"pile_set_name": "PubMed Central"
} |
**Session:** 68. Novel Antimicrobials and Approaches Against Resistant Bugs
*Thursday, October 3, 2019: 12:15 PM*
| {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
Interferons (IFNs) are secretory proteins with multiple biological properties such as antiviral, antiproliferative, and immunomodulatory activities ([@ref1][@ref2]). Due to the therapeutic potential, IFNs are currently licensed for the treatment of various viral infections, malignan... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
"When Horatius set out to defend the Roman bridge against the Etruscans, he knew full well that the city elders had already planned to cut it down, sacrificing him and the bridge in order to save the day".\[[@ref1]\] Chronic disease care in the older person, in many ways, is like a ... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-brainsci-09-00069}
===============
Electroencephalogram (EEG) assessment is a commonly utilized clinical tool for recording brain activity with the use of electrodes placed systematically on the scalp \[[@B1-brainsci-09-00069]\]. Clinical EEG assessment has existed for over 50 years relying on E... | {
"pile_set_name": "PubMed Central"
} |
Objective
=========
The aim of this work was to determine the impact of vaccination on the dynamics of mortality and the contribution of vaccine preventable infections to the structure of total infectious mortality of the population of Ukraine over the past 50 years to develop a more effective system of surveillance f... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
{
"pile_set_name": "PubMed Central"
} | |
Background
==========
The experience with asbestos highlighted that high aspect ratio particles (fibres) pose an additional hazard to the lung beyond that produced by conventional compact particles and gave rise to the discipline of fibre toxicology. Over several decades up to the present, fibre toxicology has evolved... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
*Withania somnifera* (Linn.) Dunal, commonly known as Indian Ginseng or Indian winter cherry, is recognized as the Queen of Indian herbs and has received similar admiration in Unani, Siddha, and Chinese systems of medicine [@bib1]. The roots are the most commonly used part and f... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Sarcopenia is an age-related progressive decline in muscle mass and function that contributes to increased physical disability, morbidity, and mortality among the elderly \[[@bib1]\]. The European Working Group on Sarcopenia in Older People (EWGSOP) defined sarcopenia as the pre... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
The current models of active Structure-from-Motion (SfM) are based on the Helmholtzian account of perception as inverse inference [@pone.0018731-Rao1]--[@pone.0018731-Zhong1]. According to this approach, the goal of the perceptual system is to infer from the sensory evidence the environ... | {
"pile_set_name": "PubMed Central"
} |
The study by Comelli et al. \[[@B1]\] published in a recent issue of the Journal of Epidemiology and Global Health describing the association between ambient temperature and incidence of acute-onset arterial fibrillation (AAF) in Italy was read with great interest. The authors retrieved data from the electronic health ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
The development of new responsive fluorescent probes that involve minimal perturbation of the biological system is essential for understanding the structure and the function of the cellular processes [@pone.0027078-Diaz1]. These systems must be adapted to the constraints imposed by the ... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the manuscript and its Supporting Information files.
Introduction {#sec001}
============
Deep-sea hydrothermal vents are chemosynthetic ecosystems, which are characteristed by high temperature (up to 390°C), low oxygen levels, enriched hydrogen sulfide (H~2~S), methane (CH~4~) and heavy m... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Levels of plasma free amino acid (PFAA) concentrations are determined by various factors. It is well known that PFAA balance is altered in subjects with various diseases and malnutrition, such as inborn metabolic disorder [@pone.0062929-Velazquez1], liver fibrosis [@pone.0062929-Fischer... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Schizophrenia is a serious mental disorder that affects three out of every 10, 000 adults, of the global population. Despite the low incidence, the chronic course raises the prevalence to high levels, affecting 24 million people worldwide^(^ [@B01] ^)^.
Although delusions and hallucinations ... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the manuscript and its Supporting Information files.
Background {#sec005}
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Tuberculosis (TB) is a communicable disease caused by the bacillus *Mycobacterium tuberculosis*. It usually affects the lungs (pulmonary TB) and transmitted when people who are sick with pulmonary TB expe... | {
"pile_set_name": "PubMed Central"
} |
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and bone erosion, which affects up to 1% of the population worldwide. It is the paradigm of a chronic disease, which hardly resolves and usually accompanies patients during their entire life[@b1][@b2]. This situation is par... | {
"pile_set_name": "PubMed Central"
} |
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[^1]: From the Department of Health, Phillips Academy, Andover, Mass., and the Grant Study, Department of Hygiene, Harvard University. These studies were aided by a grant from the Carnegie Corporation.
| {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Herniation of the lung is an uncommon entity which has only been reported mainly as case reports around the world. It is defined as a protrusion of lung tissue beyond the confines of the thoracic cavity through an abnormal opening in the chest wall, diaphragm or mediastinum line... | {
"pile_set_name": "PubMed Central"
} |
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