Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
A one-pot coupling/hydrolysis/condensation process to pyrrolo[1,2-a]quinoxaline. | CuI/L-proline-catalyzed coupling of 2-halotrifluoroacetanilides with pyrrole-2-carboxylate esters in DMSO at 80-90 degrees C followed by in situ hydrolysis at 60 degrees C afforded pyrrolo[1,2-a]quinoxalines. Indole-2-carboxylate esters underwent the same process smoothly to provide the corresponding tetracyclic produc... | ['Hydrolysis', 'Molecular Structure', 'Pyrroles', 'Quinoxalines'] | 18,522,423 | [['G02.380'], ['G02.111.570', 'G02.466'], ['D03.383.129.578'], ['D03.633.100.857']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mechanism of hypertensive nephropathy in the Dahl/Rapp rat: a primary disorder of vascular smooth muscle. | The Dahl/Rapp salt-sensitive (S) rat is a model of salt-sensitive hypertension and hypertensive renal disease. This study explored the role of vascular remodeling in the development of renal failure in S rats. Groups of S and Sprague-Dawley rats were given 0.3 and 8.0% NaCl diets for up to 21 days and evidence of smoot... | ['Animals', 'Bromodeoxyuridine', 'Cell Hypoxia', 'Cell Proliferation', 'Hypertension', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Kidney', 'Male', 'Muscle, Smooth, Vascular', 'Nitroimidazoles', 'Rats', 'Rats, Inbred Dahl', 'Renal Insufficiency', 'Sodium Chloride', 'Sucrose', 'Time Factors', 'Transcription Factors'] | 15,583,217 | [['B01.050'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['G03.197.300', 'G04.270.300'], ['G04.161.750', 'G07.345.249.410.750'], ['C14.907.489'], ['D12.776.260.103.625.750', 'D12.776.930.125.625.750'], ['A05.810.453'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis of 3-phenylpyrazolo[4,3-b]pyridines via a convenient synthesis of 4-amino-3-arylpyrazoles and SAR of corticotropin-releasing factor receptor type-1 antagonists. | 3-Phenylpyrazolo[4,3-b]pyridines were synthesized via a cyclization of 4-amino-3-phenylpyrazoles 11-13 with ethyl acetoacetate. These compounds were found to be potent CRF(1) antagonists. The 2-alkylpyrazolo[4,3-b]pyridines were more polar but less active than the corresponding 1-alkyl-isomers. | ['Humans', 'Pyrazoles', 'Pyridines', 'Receptors, Corticotropin-Releasing Hormone', 'Structure-Activity Relationship'] | 12,951,127 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.539'], ['D03.383.725'], ['D12.776.543.750.695.180', 'D12.776.543.750.720.600.290', 'D12.776.543.750.750.555.290', 'D12.776.543.750.750.700.150'], ['G02.111.830', 'G07.690.773.997']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of telechelic cis-1,4-polyisoprene cationomers in the synthesis of antibacterial ionic polyurethanes and copolyurethanes bearing ammonium groups. | New crosslinked ionic polyurethanes and copolyurethanes were yielded by reaction of telechelic cis-1,4-oligoisoprenes, bearing a variable number of ammonium and hydroxy groups, with isocyanurate of isophorone diisocyanate (I-IPDI). Aiming for a comparative study, polyurethane elastomers based on non-ionic telechelic ol... | ['Anti-Bacterial Agents', 'Biocompatible Materials', 'Butadienes', 'Cations', 'Disinfection', 'Hemiterpenes', 'Materials Testing', 'Pentanes', 'Polyurethanes', 'Pseudomonas aeruginosa', 'Quaternary Ammonium Compounds', 'Staphylococcus epidermidis'] | 17,610,950 | [['D27.505.954.122.085'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D02.455.326.271.665.146.240'], ['D01.248.497.300'], ['N06.850.780.200.450.850.375'], ['D02.455.849.486'], ['E05.570'], ['D02.455.326.146.770'], ['D02.241.081.251.944.750', 'D05.750.716.650', 'D25.720.327.782', 'D25.720.716.650', 'J01.637.051... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Association of serum osteoprotegerin with left ventricular mass in African American adults with hypertension. | BACKGROUND: African-Americans with hypertension are susceptible to left ventricular hypertrophy (LVH). Serum osteoprotegerin level has been reported to be associated with LVH. We investigated the association of osteoprotegerin with LV mass (LVM) in 898 African-Americans with hypertension (mean age 65 years, 71% women).... | ['African Americans', 'Aged', 'Biomarkers', 'Female', 'Heart Ventricles', 'Humans', 'Hypertension', 'Hypertrophy, Left Ventricular', 'Male', 'Middle Aged', 'Organ Size', 'Osteoprotegerin'] | 20,339,356 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['D23.101'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C14.280.195.400', 'C23.300.775.250.400'], ['M01.060.116.630'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690'], ['D12.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Value of serial troponin T measures for early and late risk stratification in patients with acute coronary syndromes. The GUSTO-IIa Investigators. | BACKGROUND: The baseline cardiac troponin T (cTnT) level strongly predicts short-term mortality in acute coronary syndromes, but the added value of later measures to predict short- and long-term outcome and in the context of baseline clinical characteristics is unclear.METHODS AND RESULTS: Relations between baseline, p... | ['Acute Disease', 'Aged', 'Coronary Disease', 'Female', 'Humans', 'Male', 'Middle Aged', 'Models, Cardiovascular', 'Myocardium', 'Prognosis', 'Proportional Hazards Models', 'Risk Assessment', 'Time Factors', 'Troponin T'] | 9,799,204 | [['C23.550.291.125'], ['M01.060.116.100'], ['C14.280.647.250', 'C14.907.585.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.599.395.161'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['E01.789'], ['E05.318.740.500.700', 'E05.318.740.600.700', 'E05.318.740.750.725', 'E05.318.740... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Syncope in the emergency department: comparison of standardized admission criteria with clinical practice. | AIMS: Syncope is a major health care problem that accounts for many emergency department (ED) and hospital admissions. This study was conducted to investigate the short-term risk of serious events in patients presenting to the ED with syncope and to compare guideline-based admission criteria with those adopted in clini... | ['Adult', 'Aged', 'Algorithms', 'Diagnostic Tests, Routine', 'Emergency Service, Hospital', 'Europe', 'Female', 'Guidelines as Topic', 'Humans', 'Male', 'Middle Aged', 'Patient Discharge', "Practice Patterns, Physicians'", 'Prevalence', 'Retrospective Studies', 'Risk Assessment', 'Syncope', 'United States'] | 21,757,485 | [['M01.060.116'], ['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['E01.370.395'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['Z01.542'], ['N04.761.700.350', 'N05.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.760.169.125', 'E02.760.400.610', 'N0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Screening and Identification of Trichoderma Strains Isolated from Natural Habitats with Potential to Cellulose and Xylan Degrading Enzymes Production. | A total of 123 Trichoderma strains were isolated from different habitats and tested for their ability to degrade cellulose and xylan by simple plate screening method. Among strains, more than 34 and 45% respectively, exhibited higher cellulolytic and xylanolytic activity, compared to the reference strain T. reesei QM 9... | ['Biomass', 'Cellulase', 'Cellulose', 'Ecosystem', 'Lignin', 'Soil Microbiology', 'Temperature', 'Trichoderma', 'Wood', 'Xylans'] | 30,015,456 | [['G16.500.275.157.100', 'N06.230.124.100'], ['D08.811.277.450.420.200.200'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['G16.500.275.157', 'N06.230.124'], ['D05.750.078.562.180.515', 'D05.750.078.687', 'D20.538', 'D25.720.099.687', 'J01.637.051.720.099.687'], ['H01.158.2... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
SERPINA3 is a key modulator of HNRNP-K transcriptional activity against oxidative stress in HCC. | Most studies about serpin peptidase inhibitor, clade A member 3 (SERPINA3) has been limited to its inhibitory functions and mechanisms. Herein, we report a novel role of SERPINA3 in transcriptional regulation of HCC progression-related genes. Among 19 selected genes through HCC cell isolation system based on telomere l... | ['Animals', 'Carcinoma, Hepatocellular', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Transformation, Neoplastic', 'Disease Models, Animal', 'Gene Expression Regulation, Neoplastic', 'Heterogeneous-Nuclear Ribonucleoprotein K', 'Heterografts', 'Humans', 'Liver Neoplasms', 'Mice', 'Oxidative Stress', 'Protein Binding... | 31,121,493 | [['B01.050'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.697.098.500', 'C23.550.727.098.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.308.370'], ['D12.776.157.725.813.750.50... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Age-related use and benefit of the bone-anchored hearing aid compact. | OBJECTIVE: To study age-related patient satisfaction with the bone-anchored hearing aid (BAHA) compact.METHODS: A retrospective postal questionnaire, the International Outcome Inventory for Hearing Aids (IOI-HA), was sent to 211 BAHA Compact users. Questionnaire responses from 135 BAHA users were analyzed related to ag... | ['Adolescent', 'Adult', 'Aged', 'Aging', 'Audiometry, Pure-Tone', 'Communication', 'Female', 'Hearing Aids', 'Hearing Loss', 'Hearing Loss, Conductive', 'Hearing Loss, Mixed Conductive-Sensorineural', 'Hearing Loss, Sensorineural', 'Humans', 'Male', 'Middle Aged', 'Patient Satisfaction', 'Speech Perception', 'Surveys a... | 19,638,942 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['E01.370.382.375.060.055'], ['F01.145.209', 'L01.143'], ['E07.305.906.500', 'E07.814.458'], ['C09.218.458.341', 'C10.597.751.418.341', 'C23.888.592.763.393.341'], ['C09.218.458.341.562', 'C10.597.751.418.341.562', 'C23.888.592.763.393.341.562'], ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Transactivation potencies of the Baikal seal (Pusa sibirica) peroxisome proliferator-activated receptor á by perfluoroalkyl carboxylates and sulfonates: estimation of PFOA induction equivalency factors. | The present study assessed the transactivation potencies of the Baikal seal (Pusa sibirica) peroxisome proliferator-activated receptor á (BS PPARá) by perfluorochemicals (PFCs) having various carbon chain lengths (C4-C12) using an in vitro reporter gene assay. Among the twelve PFCs treated with a range of 7.8-250 ìM co... | ['Animals', 'Caprylates', 'Dose-Response Relationship, Drug', 'Fluorocarbons', 'Gene Expression', 'PPAR alpha', 'RNA, Messenger', 'Seals, Earless', 'Transcriptional Activation', 'Water Pollutants, Chemical'] | 21,381,677 | [['B01.050'], ['D02.241.081.222', 'D10.251.122'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.455.526.510.435'], ['G05.297'], ['D12.776.826.239.500'], ['D13.444.735.544'], ['B01.050.150.900.649.313.750.250.700'], ['G05.308.800'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tauroursodeoxycholic acid activates protein kinase C in isolated rat hepatocytes. | BACKGROUND & AIMS: Ursodeoxycholic acid (UDCA) improves liver function in patients with chronic cholestatic liver diseases by an unknown mechanism. UDCA is conjugated to taurine in vivo, and tauroursodeoxycholic acid (TUDCA) is a potent hepatocellular Ca2+ agonist and stimulates biliary exocytosis and hepatocellular Ca... | ['Animals', 'Cell Membrane', 'Cells, Cultured', 'Cholagogues and Choleretics', 'Cytosol', 'Diglycerides', 'Enzyme Activation', 'Exocytosis', 'Isoenzymes', 'Liver', 'Male', 'Protein Kinase C', 'Rats', 'Rats, Sprague-Dawley', 'Taurochenodeoxycholic Acid', 'Taurocholic Acid'] | 8,613,063 | [['B01.050'], ['A11.284.149'], ['A11.251'], ['D27.505.954.483.508'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D10.351.303'], ['G02.111.263', 'G03.328'], ['G04.468'], ['D08.811.348', 'D12.776.800.300'], ['A03.620'], ['D08.811.913.696.620.682.700.725'], ['B01.050.150.900.649.313.992.635.50... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Transitory postural and positional nystagmus in children and its diagnostic significance]. | Among 587 children at an age from 5 to 14 years, examined in the university clinic of O.R.L. Essen in a 10 years period because of dizziness, 201 times the subjective sensations could be objectified by a vestibular nystagmus. After elimination of all cases with a pathologic ear state 39 times a posture or positioning n... | ['Adolescent', 'Child', 'Child, Preschool', 'Humans', 'Nystagmus, Pathologic', 'Posture', 'Vertigo'] | 6,633,543 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.292.562.675', 'C11.590.400'], ['G11.427.695'], ['C09.218.568.900.883', 'C10.597.951', 'C23.888.592.958']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A novel nonsense mutation of the KAL gene in two brothers with Kallmann syndrome. | Kallmann syndrome (KS), defined by the association of hypogonadotropic hypogonadism and anosmia or hyposmia, can be caused by mutations in the KAL gene on Xp 22.3. This gene encodes an extracellular matrix glycoprotein called anosmin-1, which belongs to the class of cell adhesion molecules. In the absence of a function... | ['Adolescent', 'Codon, Nonsense', 'Exons', 'Extracellular Matrix Proteins', 'Genetic Linkage', 'Humans', 'Kallmann Syndrome', 'Male', 'Nerve Tissue Proteins', 'Polymerase Chain Reaction', 'Polymorphism, Single-Stranded Conformational', 'Sequence Analysis, DNA', 'X Chromosome'] | 11,044,805 | [['M01.060.057'], ['D13.444.735.544.355.250.235', 'G05.360.335.355.250.235', 'G05.365.590.195'], ['G05.360.340.024.340.137.232'], ['D12.776.860.300'], ['G05.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.706.316.096.750', 'C13.351.875.253.096.750', 'C16.131.939.316.096.750', 'C16.320.467', 'C19.391.119.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Lowered cAMP and cGMP signalling in the brain during levodopa-induced dyskinesias in hemiparkinsonian rats: new aspects in the pathogenetic mechanisms. | Dysregulation of dopamine receptors is thought to underlie levodopa-induced dyskinesias in experimental models of Parkinson's disease. It is unknown whether an imbalance of the second messengers, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), is involved in the alterations of levodopa/... | ['Animals', 'Animals, Newborn', 'Brain', 'Cerebral Cortex', 'Cyclic AMP', 'Cyclic GMP', 'Dopamine', 'Dopamine Agents', 'Down-Regulation', 'Dyskinesia, Drug-Induced', 'Globus Pallidus', 'Levodopa', 'Male', 'Neostriatum', 'Oxidopamine', 'Parkinsonian Disorders', 'Phosphodiesterase Inhibitors', 'Phosphorylation', 'Purinon... | 18,717,735 | [['B01.050'], ['B01.050.050.282'], ['A08.186.211'], ['A08.186.211.200.885.287.500'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['D02.092.211.215.406', 'D02.092.311.34... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adolescent substance use, sleep, and academic achievement: evidence of harm due to caffeine. | Using academic achievement as the key outcome variable, 7377 Icelandic adolescents were surveyed for cigarette smoking, alcohol use, daytime sleepiness, caffeine use, and potential confounders. Structural equation modeling (SEM) was used to examine direct and indirect effects of measured and latent variables in two mod... | ['Adolescent', 'Adolescent Behavior', 'Caffeine', 'Central Nervous System Stimulants', 'Cross-Sectional Studies', 'Educational Status', 'Female', 'Humans', 'Iceland', 'Male', 'Sleep', 'Sleep Deprivation', 'Substance-Related Disorders'] | 20,970,177 | [['M01.060.057'], ['F01.145.022'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D27.505.696.282', 'D27.505.954.427.220'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.816.249', 'Z01.639.490'], ['F02.83... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Perinatal effects of Gardnerella vaginalis deciduitis in the rabbit. | OBJECTIVE: We determined the effects of intrauterine infection with Gardnerella vaginalis on maternal and fetal outcome in the rabbit.STUDY DESIGN: Both uterine horns of rabbits on day 20 or 21 of gestation (70% of gestation) were inoculated hysteroscopically with either 0.2 ml of 10(5) to 10(7) CFU/ml of G. vaginalis ... | ['Animals', 'Bacterial Infections', 'Birth Weight', 'Brain', 'Brain Diseases', 'Decidua', 'Endometritis', 'Female', 'Fetal Death', 'Fetal Diseases', 'Fever', 'Gardnerella vaginalis', 'Obstetric Labor, Premature', 'Organ Size', 'Placenta', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Pregnancy Outcome', 'Rabbits... | 8,456,914 | [['B01.050'], ['C01.150.252'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['A08.186.211'], ['C10.228.140'], ['A05.360.319.679.490.373', 'A16.710.289'], ['C13.351.500.056.750.249', 'C13.351.500.852.299'], ['C13.703.223', 'C23.5... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
gamma-Glutamyltransferase predicts cardiovascular death among Japanese women. | The clinical importance of gamma-glutamyltransferase (GGT) has recently been debated. Although some studies have suggested that the relationship between GGT and cardiovascular disease (CVD) mortality is independent of alcohol consumption, to our knowledge no studies have reported the relationship between GGT and CVD mo... | ['Biomarkers', 'Cardiovascular Diseases', 'Female', 'Follow-Up Studies', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Prospective Studies', 'Risk Factors', 'Sex Factors', 'gamma-Glutamyltransferase'] | 17,034,795 | [['D23.101'], ['C14'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E05.318.372.500.750... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Intercondylar Notch Width as a Risk Factor for Medial Femoral Condyle Osteochondritis Dissecans in Skeletally Immature Patients. | BACKGROUND: Juvenile osteochondritis dissecans (OCD) of the medial femoral condyle (MFC) is one of the most common causes of knee pain in adolescents. Wilson sign reproduces knee pain with internal rotation of the tibia during extension of the knee from 90 to 30 degrees due to impingement of the tibial eminence on the ... | ['Adolescent', 'Australia', 'Case-Control Studies', 'Child', 'Female', 'Femur', 'Humans', 'Kinanthropometry', 'Knee Joint', 'Magnetic Resonance Imaging', 'Male', 'Osteochondritis Dissecans', 'Radiography', 'Reproducibility of Results', 'Retrospective Studies', 'Risk Factors', 'Tibia'] | 25,988,680 | [['M01.060.057'], ['Z01.639.100', 'Z01.678.100.373'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['A02.835.232.043.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.600.024.450', 'N06.850.505.200.100.700'], ['A02.835.583.475'], ['E01.370.350.825.500']... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
NAD(P)H quinone oxidoreductase 1 is essential for ozone-induced oxidative stress in mice and humans. | One host susceptibility factor for ozone identified in epidemiologic studies is NAD(P)H quinone oxidoreductase 1 (NQO1). We hypothesized that after ozone exposure, NQO1 is required to increase 8-isoprostane (also known as F(2)-isoprostane) production, a recognized marker of ozone-induced oxidative stress, and to enhanc... | ['Animals', 'Bronchi', 'Bronchial Hyperreactivity', 'Bronchial Provocation Tests', 'Cells, Cultured', 'Chemokines', 'Dicumarol', 'Dinoprost', 'Enzyme Inhibitors', 'Epithelial Cells', 'Humans', 'Interleukin-8', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'NAD(P)H Dehydrogenase (Quinone)', 'NADPH Dehydrogenase', 'Oxi... | 19,059,883 | [['B01.050'], ['A04.411.125'], ['C08.127.210'], ['E01.370.386.700.125'], ['A11.251'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['D03.383.663.283.446.520.203', 'D03.633.100.150.446.520.203'], ['D10.251.355.255.550.400.200', 'D23.469.050.175.725.400.200'], ['D27.505... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Mechanisms of antimicrobial resistance]. | Most fundamental differences in the bacterial structure between the gram positive and negative bacteria are whether the organism has the outer membrane. The most essential mechanism of antimicrobial resistance in the gram negative bacteria are the alteration of membrane permeability to antibiotics. The outer membrane c... | ['Aminoglycosides', 'Anti-Bacterial Agents', 'Drug Resistance, Microbial', 'Gram-Negative Bacteria', 'Gram-Positive Bacteria', 'Lactams', 'Macrolides', 'Methicillin Resistance', 'Quinolones', 'Staphylococcus aureus', 'Vancomycin'] | 8,126,881 | [['D09.408.051'], ['D27.505.954.122.085'], ['G06.225', 'G07.690.773.984.269'], ['B03.440'], ['B03.510'], ['D02.065.589', 'D03.383.411'], ['D02.540.505', 'D02.540.576.500', 'D04.345.674.500'], ['G06.099.225.500.600.525', 'G06.225.347.500.600.525', 'G07.690.773.984.269.347.500.600.525'], ['D03.633.100.810.835'], ['B03.30... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of spontaneously released endothelium-derived relaxing factor in cerebral and extracerebral arteries in rabbits. | To investigate regional differences in spontaneously released endothelium-derived relaxing factor (EDRF), a bioassay of spontaneously released EDRF was performed on rabbit basilar, ear, common carotid and thoracic arteries using an isometric tension measurement technique and a measurement of cyclic guanosine monophosph... | ['Acetylcholine', 'Animals', 'Arteries', 'Basilar Artery', 'Biomarkers', 'Carotid Arteries', 'Cyclic GMP', 'Ear', 'Endothelium, Vascular', 'Hemoglobins', 'Male', 'Muscle Proteins', 'Muscle, Smooth, Vascular', 'Nitric Oxide', 'Rabbits', 'Saponins', 'Secretory Rate', 'Serotonin', 'Thoracic Arteries', 'Vasodilation'] | 7,905,607 | [['D02.092.211.111'], ['B01.050'], ['A07.015.114'], ['A07.015.114.106'], ['D23.101'], ['A07.015.114.186'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['A01.456.313', 'A09.246'], ['A07.015.700.500', 'A10.272.491.355'], ['D12.776.124.400', 'D12.776.422.316.762'], ['D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multiple binding modes for palmitate to barley lipid transfer protein facilitated by the presence of proline 12. | Molecular dynamics simulations have been used to characterise the binding of the fatty acid ligand palmitate in the barley lipid transfer protein 1 (LTP) internal cavity. Two different palmitate binding modes (1 and 2), with similar protein-ligand interaction energies, have been identified using a variety of simulation... | ['Binding Sites', 'Carrier Proteins', 'Fatty Acid-Binding Proteins', 'Hydrogen Bonding', 'Ligands', 'Models, Molecular', 'Molecular Dynamics Simulation', 'Palmitates', 'Proline'] | 23,139,016 | [['G02.111.570.120'], ['D12.776.157'], ['D12.776.157.170'], ['G02.282'], ['D27.720.470.480'], ['E05.599.595'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D10.251.694.600'], ['D12.125.072.401.623']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Nonolfactory sensory pathway to the telencephalon in a teleost fish. | Pathways conveying lateral-line sensory information within the brain of a bullhead catfish terminate in a localized zone within the telencephalon. Thus, the telencephalon in teleosts, as in amniote species, contains regions that receive specific sensory input. Therefore, this lemniscal organization is not restricted to... | ['Afferent Pathways', 'Animals', 'Biological Evolution', 'Electricity', 'Fishes', 'Mechanoreceptors', 'Smell', 'Telencephalon'] | 7,192,013 | [['A08.612.220'], ['B01.050'], ['G05.045', 'G16.075'], ['G01.358.500.249'], ['B01.050.150.900.493'], ['A08.675.650.915.750', 'A08.800.950.750', 'A11.671.650.915.750'], ['F02.830.816.643', 'G11.561.790.643'], ['A08.186.211.200.885']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-dose Ara-C for remission induction and consolidation of previously untreated adults with ALL or lymphoblastic lymphoma. | Thirty-two patients with untreated ALL (n = 26) or lymphoblastic lymphoma (n = 6) between 17 and 65 years of age were treated with a short remission induction course with VP16-213, amsacrine, intermediate dose Ara-C for 6 days, prednisone and intrathecal methotrexate, followed by a consolidation course with vincristine... | ['Adolescent', 'Adult', 'Amsacrine', 'Antineoplastic Combined Chemotherapy Protocols', 'Bone Marrow Transplantation', 'Cytarabine', 'Dose-Response Relationship, Drug', 'Etoposide', 'Female', 'Humans', 'Male', 'Methotrexate', 'Middle Aged', 'Pilot Projects', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Prednisone'... | 7,880,926 | [['M01.060.057'], ['M01.060.116'], ['D03.633.300.046.250.225'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.095.147.725.040', 'E04.936.580.040'], ['D03.383.742.680.245.453', 'D13.570.065.300', 'D13.570.685.245.453'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.455.426.559.847.638.960.675.250', 'D... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Regulation of sarcoplasmic reticulum gene expression during cardiac and skeletal muscle development. | The expression of major sarcoplasmic reticulum proteins during cardiac and fast-twitch skeletal muscle development was examined using gene-specific probes. Through the use of S1 nuclease mapping, Northern blot, and RNA slot-blot analysis, sarcoplasmic reticulum proteins were shown to exhibit both narrow tissue specific... | ['Actins', 'Animals', 'Calcium-Binding Proteins', 'Calcium-Transporting ATPases', 'Calsequestrin', 'Cell Line, Transformed', 'Cells, Cultured', 'Female', 'Gene Expression Regulation', 'Heart', 'Isoenzymes', 'Male', 'Mice', 'Muscle Development', 'Muscle Proteins', 'Muscles', 'Myogenin', 'RNA', 'Rabbits', 'Receptors, Cho... | 1,372,478 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['D12.776.157.125'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', 'D12.776.157.530.813.250', 'D12.776.543.585.450.250.500', 'D12.776.543.585.813.250'], ['D12.776.157.125.155', 'D12.776.210.500.220'], ['A11.251.210.172... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Polarization-induced charge distribution at homogeneous zincblende/wurtzite heterostructural junctions in ZnSe nanobelts. | Homogeneous heterostructural wurtzite (WZ)/zincblende (ZB) junctions are successfully fabricated in ZnSe nanobelts. Polarity continuity across the ZB/WZ interface is demonstrated. The saw-tooth-like potential profile induced by spontaneous polarization across the WZ/ZB/WZ interfaces is identified directly at the nanosc... | ['Electrons', 'Models, Molecular', 'Molecular Conformation', 'Nanostructures', 'Selenium Compounds', 'Sulfides', 'Zinc', 'Zinc Compounds'] | 22,298,439 | [['G01.249.335', 'G01.358.500.750'], ['E05.599.595'], ['G02.111.570.820'], ['J01.637.512'], ['D01.810'], ['D01.248.497.158.874', 'D01.875.350.850', 'D02.886.520'], ['D01.268.556.940', 'D01.268.956.906', 'D01.552.544.940'], ['D01.975']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
N-acetylcysteine reverses cardiac myocyte dysfunction in HIV-Tat proteinopathy. | HIV cardiomyopathy remains highly prevalent among the estimated 33 million HIV-infected individuals worldwide. This is particularly true in developing countries. Potential mechanisms responsible for myocardial dysfunction following HIV infection include direct effects of HIV proteins. We have previously reported that c... | ['Acetylcysteine', 'Adenosine Triphosphate', 'Animals', 'Antiviral Agents', 'Calcium', 'Cardiomyopathies', 'Catalase', 'Female', 'Gene Products, tat', 'Glutathione', 'Glutathione Peroxidase', 'HIV Infections', 'Hydrogen Peroxide', 'Male', 'Mice', 'Mice, Transgenic', 'Myocardial Contraction', 'Myocytes, Cardiac', 'Oxida... | 22,556,393 | [['D02.886.030.230.259', 'D12.125.166.230.259'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D27.505.954.122.388'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C14.280.238'], ['D08.811.682.732.332'], ['D12.776.260.755.199', 'D12.776.930.900.199', 'D12.776.9... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Spontaneous intrahepatic porto-cava shunt associated with chronic pericarditis. A case report]. | INTRODUCTION: Spontaneous intrahepatic portosystemic shunts are rare vascular anomalies that consist of a communication between the portal system and the systemic venous circulation. We report a case of a porto-caval shunt associated with chronic pericarditis.CASE REPORT: A 47-year-old patient with post pericarditis ci... | ['Aneurysm', 'Humans', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Pericarditis, Constrictive', 'Portal Vein', 'Tomography, Spiral Computed', 'Ultrasonography, Doppler, Color', 'Vascular Fistula', 'Vena Cava, Inferior'] | 18,236,819 | [['C14.907.055'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['M01.060.116.630'], ['C14.280.720.595'], ['A07.015.908.670.567'], ['E01.370.350.350.810.800', 'E01.370.350.600.350.700.810.800', 'E01.370.350.700.700.810.800', 'E01.370.350.700.810.810.800', 'E01.370.350.825.810.810.... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Emergency appendicectomy: a one year audit. | A retrospective study of emergency appendicectomy over a one-year period at Beaumont Hospital was carried out. The overall normal appendicectomy rate was 22.8%, and was twice as high in women (31%) as in men (15%). Gangrenous or perforated appendicitis was present in 20% of cases. The overall mean assessment-surgery in... | ['Acute Disease', 'Adolescent', 'Adult', 'Appendectomy', 'Appendicitis', 'Emergencies', 'Female', 'Humans', 'Ireland', 'Male', 'Medical Audit', 'Middle Aged', 'Retrospective Studies', 'Utilization Review'] | 1,428,756 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['E04.210.078'], ['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.467', 'Z01.639.587'], ['N04.761.700.250.500', 'N05.700.175.500'], ['M01.06... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Non-traditional adipokines in pediatric HIV-related lipodystrophy: a-FABP as a biomarker of central fat accumulation. | BACKGROUND: Lipodystrophy characterized by adipose tissue redistribution and lipid and glucose metabolism abnormalities, is common among HIV-infected adults and children on highly-active-antiretroviral-therapy (HAART). In a previous study of HIV-infected children, we did not detect insulin resistance, despite a high pe... | ['Abdominal Fat', 'Acute-Phase Proteins', 'Adipokines', 'Adiposity', 'Adolescent', 'Anti-HIV Agents', 'Antiretroviral Therapy, Highly Active', 'Biomarkers', 'Body Fat Distribution', 'Child', 'Child, Preschool', 'Chitinase-3-Like Protein 1', 'Fatty Acid-Binding Proteins', 'Female', 'HIV Infections', 'Humans', 'Lectins',... | 24,266,781 | [['A10.165.114.830.500'], ['D12.776.124.050'], ['D06.472.699.042', 'D12.644.276.024', 'D12.644.548.011', 'D12.776.467.024', 'D23.529.024'], ['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['M01.060.057'], ['D27.505.954.122.388.077.088'], ['E02.319.310.075'], ['D23.101']... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evidence for a conserved role of retinoic acid in urodele amphibian meiosis onset. | Pleurodeles waltl is a urodele amphibian displaying a ZZ/ZW genetic mode of sex determination. Gonad differentiation can later be modulated by hormone treatment. To investigate germ cell differentiation, we analyzed the expression of the meiosis marker PwDmc1 and show that germ cells enter meiosis in late larval life i... | ['Animals', 'Biomarkers', 'Cell Differentiation', 'Cytochrome P-450 Enzyme System', 'Female', 'Germ Cells', 'Male', 'Meiosis', 'Metamorphosis, Biological', 'Ovary', 'Pleurodeles', 'Retinoic Acid 4-Hydroxylase', 'Sex Determination Processes', 'Signal Transduction', 'Testis', 'Tissue Culture Techniques', 'Tretinoin'] | 19,347,951 | [['B01.050'], ['D23.101'], ['G04.152'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['A05.360.490', 'A11.497'], ['G04.144.220.220.687', 'G05.113.220.687'], ['G07.345.500.550'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['B01.050.150.900.090.608.700.540'], ['D08.244.453.498.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hybrid facial image feature extraction and recognition for non-invasive chronic fatigue syndrome diagnosis. | Due to an absence of reliable biochemical markers, the diagnosis of chronic fatigue syndrome (CFS) mainly relies on the clinical symptoms, and the experience and skill of the doctors currently. To improve objectivity and reduce work intensity, a hybrid facial feature is proposed. First, several kinds of appearance feat... | ['Algorithms', 'Case-Control Studies', 'Eyelids', 'Face', 'Fatigue Syndrome, Chronic', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Male', 'Pattern Recognition, Automated', 'Skin Aging'] | 26,117,650 | [['G17.035', 'L01.224.050'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A01.456.505.420.504', 'A09.371.337'], ['A01.456.505'], ['C01.925.330', 'C05.651.310', 'C10.228.440.600', 'C10.668.364'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Perfectionism in weight-concerned and -unconcerned women: an experimental approach. | OBJECTIVE: The primary purpose of the study was to explore, experimentally, the common clinical observation that anorexics are highly perfectionistic.METHOD: Extremely weight-concerned and control college student subjects (as defined by scores on the Eating Attitudes Test [EAT]) were assigned high or low goals or they ... | ['Adolescent', 'Adult', 'Anorexia Nervosa', 'Body Image', 'Body Weight', 'Creativity', 'Defense Mechanisms', 'Feedback', 'Female', 'Humans', 'Internal-External Control', 'Motivation', 'Personality Assessment', 'Self Concept', 'Socialization'] | 8,859,396 | [['M01.060.057'], ['M01.060.116'], ['F03.400.125'], ['F01.752.747.792.110', 'F02.463.593.112'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['F01.752.264', 'F02.463.785.302'], ['F01.393'], ['L01.906.394.211'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 |
Basophilic leukocytes in allergic contact dermatitis. | A variety of cell-mediated hypersensitivity reactions in experimental animals include a prominent infiltrate of basophilic leukocytes. This form of reactivity has been designated cutaneous basophil hypersensitivity and is favored when sensitization to several types of antigen is accomplished without the use of complete... | ['Adult', 'Alkenes', 'Basophils', 'Biopsy', 'Catechols', 'Dermatitis, Contact', 'Edema', 'Eosinophils', 'Fibrin', 'Humans', 'Hypersensitivity, Delayed', 'Immunity, Cellular', 'Inflammation', 'Lymphocytes', 'Male', 'Skin', 'Skin Tests'] | 5,060,290 | [['M01.060.116'], ['D02.455.326.271'], ['A11.118.637.415.120', 'A11.627.340.120', 'A15.145.229.637.415.120', 'A15.382.490.315.120'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D02.455.426.559.389.657.166'], ['C17.800.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes. | Chemoprevention involves the use of natural or synthetic substances to reduce the risk of developing cancer. Two dietary components capable of mediating chemopreventive activity in animal models by modulation of drug-metabolizing enzymes are sulforaphane, an aliphatic isothiocyanate, and brassinin, an indole-based dith... | ['Animals', 'Anticarcinogenic Agents', 'Chloramphenicol O-Acetyltransferase', 'Enzyme Induction', 'Female', 'Genes, Regulator', 'Glutathione', 'Humans', 'Isothiocyanates', 'Liver', 'Mammary Neoplasms, Experimental', 'Mice', 'Mice, Inbred BALB C', 'NAD(P)H Dehydrogenase (Quinone)', 'Organ Culture Techniques', 'RNA, Mess... | 9,000,567 | [['B01.050'], ['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['D08.811.913.050.134.170'], ['G05.308.320.200'], ['G05.360.340.024.340.425'], ['D12.644.456.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.500.375', 'D02.886.250'], ['A03.620'], ['C04.588.531.500', 'C04.619.590', 'E05.598.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence of hepatitis G virus in liver disease. | The prevalence of hepatitis G virus (HGV) in liver disease of non-A, -B, -C viral hepatitis, hepatitis B and hepatitis C was determined. Two of 44 patients (4.5%) with liver injury without any hepatitis A, B or C marker were positive for HGV. One of five cases of hepatocellular carcinoma was positive for HGV. One of th... | ['Adolescent', 'Adult', 'Aged', 'Diabetes Complications', 'Female', 'Flaviviridae', 'Hepatitis, Chronic', 'Hepatitis, Viral, Human', 'Humans', 'Male', 'Middle Aged', 'Seroepidemiologic Studies', 'Transfusion Reaction'] | 10,625,323 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C19.246.099'], ['B04.820.578.344'], ['C06.552.380.350'], ['C01.925.440', 'C06.552.380.705'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.950', 'N05.715.360.330.500.950', 'N06.850.520.450.500.950'], ['C15.378.962', 'C20... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Temporal Changes in Concentrations of Lead and Other Trace Metals in Free-Ranging Eurasian Eagle Owls Bubo bubo in Sweden. | Patterns of lead and other trace metals were examined in 122 Eurasian eagle owls Bubo bubo found dead in Sweden in the period 1978-2013. Environmental lead (Pb) has decreased over recent decades from reduced anthropogenic emissions but mortality by Pb poisoning is still frequently reported for avian raptors and scaveng... | ['Animals', 'Environmental Monitoring', 'Environmental Pollutants', 'Female', 'Isotopes', 'Lead', 'Lead Poisoning', 'Liver', 'Male', 'Metals', 'Strigiformes', 'Sweden', 'Trace Elements'] | 31,312,864 | [['B01.050'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D27.888.284'], ['D01.496'], ['D01.268.556.435', 'D01.552.544.435'], ['C25.723.522.750'], ['A03.620'], ['D01.552'], ['B01.050.150.900.248.815.550'], ['Z01.542.816.500'], ['D01.268.811', 'D27.505.696.494.555', 'G07.203.300.681.500.555', 'J02.500.681.500.555']] | ['Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Retraction and remodeling of rod spherules are early events following experimental retinal detachment: an ultrastructural study using serial sections. | PURPOSE: To describe changes induced by retinal detachment in the ultrastructure and organization of rod terminals and their connections with B-type horizontal cell (HC) axon terminals and rod bipolar cell (RB) dendrites.METHODS: Sections from control, 3 day, 7 day, and 28 day detached feline retinas were prepared for ... | ['Animals', 'Cats', 'Disease Models, Animal', 'Immunohistochemistry', 'Microscopy, Confocal', 'Models, Biological', 'Presynaptic Terminals', 'Retinal Detachment', 'Retinal Rod Photoreceptor Cells', 'Synaptic Potentials'] | 19,137,070 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512'... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Stratification in nonparametric ROC studies. | In many clinical experiments it is clear that external factors can affect the performance of diagnostic tests as these factors influence the distributions of separator variables. The authors investigate how stratification of cases and/or controls can be used in nonparametric received operating characteristic (ROC) stud... | ['Analysis of Variance', 'Biometry', 'Breast Neoplasms', 'Coronary Disease', 'Diagnosis', 'Female', 'Humans', 'Male', 'Models, Statistical', 'Proportional Hazards Models', 'ROC Curve'] | 8,086,598 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.740.225', 'N06.850.505.200'], ['C04.588.180', 'C17.800.090.500'], ['C14.280.647.250', 'C14.907.585.250'], ['E01'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Tobacco smoking contributes little to facial wrinkling. | BACKGROUND: The potential detrimental effects of tobacco smoking have been widely cited. Tobacco smoking has been linked with facial wrinkling, but some previous studies have failed to take into account a number of potential confounders or were unblinded and thus subjective to bias.OBJECTIVE: This study was designed to... | ['Adult', 'Age Factors', 'Aged', 'Bias', 'Body Weight', 'Confounding Factors, Epidemiologic', 'Educational Status', 'Eye Color', 'Face', 'Female', 'Forecasting', 'Humans', 'Linear Models', 'Male', 'Melanosis', 'Middle Aged', 'Risk-Taking', 'Sex Factors', 'Single-Blind Method', 'Skin Aging', 'Smoking', 'Sunlight', 'Suns... | 10,343,942 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['N05.715.350.150', 'N06.850.490.500'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['N05.715.350.240', 'N06.850.490.718'], ['N01.824.196'], ['G14.340', 'G16.690.360'],... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Dynamic magnetic fields remote-control apoptosis via nanoparticle rotation. | The ability to control the movement of nanoparticles remotely and with high precision would have far-reaching implications in many areas of nanotechnology. We have designed a unique dynamic magnetic field (DMF) generator that can induce rotational movements of superparamagnetic iron oxide nanoparticles (SPIONs). We exa... | ['Animals', 'Antibodies', 'Apoptosis', 'Biological Transport', 'Cell Line, Tumor', 'Ferric Compounds', 'Humans', 'Lysosomal-Associated Membrane Protein 1', 'Lysosomes', 'Magnetic Fields', 'Nanoparticles', 'Rats', 'Rotation'] | 24,597,847 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G04.146.954.035'], ['G03.143'], ['A11.251.210.190', 'A11.251.860.180'], ['D01.490.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.395.550.550.500', 'D12.776.395.550.625.449', 'D12.776.543.550.527.500', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Multiple intracellular signaling pathways orchestrate adipocytic differentiation of human bone marrow stromal stem cells. | Bone marrow adipocyte formation plays a role in bone homeostasis and whole body energy metabolism. However, the transcriptional landscape and signaling pathways associated with adipocyte lineage commitment and maturation are not fully delineated. Thus, we performed global gene expression profiling during adipocyte diff... | ['Adipocytes', 'Adipogenesis', 'Animals', 'Bone Marrow Cells', 'Cell Differentiation', 'Gene Expression Regulation, Developmental', 'Humans', 'Mesenchymal Stem Cells', 'Osteoblasts', 'Osteogenesis', 'Signal Transduction'] | 29,298,881 | [['A11.329.114'], ['G04.152.149'], ['B01.050'], ['A11.148', 'A15.378.316'], ['G04.152'], ['G05.308.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.830.500', 'A11.872.590.500'], ['A11.329.629'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729'], ['G02.111.820', 'G04.835']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Brain activity assessed with PET during recall of word lists and narratives. | This study investigated the functional neuroanatomy involved in retrieval of structured versus unstructured verbal information. We compared cerebral blood flow using PET with the [15O]water method while subjects engaged in recall of novel and practised narratives and lists of unrelated words. Left orbital frontal corte... | ['Adult', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Male', 'Mental Recall', 'Reference Values', 'Tomography, Emission-Computed', 'Verbal Learning'] | 9,331,920 | [['M01.060.116'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['E05.978.810'], ['E01.370.350.350.800', 'E01.370.350.600.350.800', 'E01.370.350.710.800', 'E01.370.350.825.800', 'E01.370.384.730.800'], ['F02.463.425.952']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effective fragment potential study of the interaction of DNA bases. | Hydrogen-bonded and stacked structures of adenine-thymine and guanine-cytosine nucleotide base pairs, along with their methylated analogues, are examined with the ab inito based general effective fragment potential (EFP2) method. A comparison of coupled cluster with single, double, and perturbative triple (CCSD(T)) ene... | ['Base Pairing', 'DNA', 'Hydrogen Bonding', 'Quantum Theory'] | 21,877,717 | [['G02.111.570.820.486.100', 'G02.111.611.500', 'G05.360.580.100'], ['D13.444.308'], ['G02.282'], ['H01.671.579.800']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of vitamin B6 status on psychological distress in a longitudinal study of HIV-1 infection. | OBJECTIVE: Inadequate vitamin B6 status has been associated with altered neuropsychiatric function, possibly through its effect on the metabolism of neurotransmitters, including serotonin (5-HT). The present eighteen month longitudinal study evaluated the relationship between vitamin B6 status and psychological distres... | ['AIDS Dementia Complex', 'Adaptation, Psychological', 'Adult', 'HIV Infections', 'HIV-1', 'Homosexuality, Male', 'Humans', 'Life Change Events', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Nutrition Assessment', 'Social Support', 'Vitamin B 6 Deficiency'] | 7,890,479 | [['C01.221.250.875.049', 'C01.221.812.640.400.070', 'C01.778.640.400.070', 'C01.925.782.815.616.400.049', 'C01.925.813.400.070', 'C10.228.140.380.070', 'C20.673.480.070', 'F03.615.400.050'], ['F01.058'], ['M01.060.116'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.8... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Transcatheter Mitral Valve Edge-to-Edge Repair with the New MitraClip XTR System for Acute Mitral Regurgitation Caused by Papillary Muscle Rupture. | Treatment of patients presenting with cardiogenic shock due to acute mitral regurgitation related to papillary muscle rupture poses significant challenges, owing to the high risk associated with conventional surgery. We hereby report successful transcatheter mitral valve edge-to-edge repair with the new Mitraclip XTR d... | ['Acute Disease', 'Cardiac Catheterization', 'Echocardiography, Three-Dimensional', 'Echocardiography, Transesophageal', 'Heart Rupture, Post-Infarction', 'Heart Valve Prosthesis Implantation', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve', 'Mitral Valve Insufficiency', 'Papillary Muscles', 'Prosthesis Design'] | 31,604,669 | [['C23.550.291.125'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E01.370.350.130.750.230', 'E01.370.350.400.200', 'E01.370.350.850.220.230', 'E01.370.370.380.220.230'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['C14.280.470.475'], ['E04.100.376.485', 'E04.650.410'... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The rat corticotropin-releasing hormone gene. | In this paper we have described the isolation and characterization of the rat corticotropin releasing hormone gene. Nucleotide sequence comparisons with the human CRH gene have demonstrated several interesting regions of homology and suggest that the gene was highly conserved through evolution. Additionally we have dem... | ['Animals', 'Cloning, Molecular', 'Corticotropin-Releasing Hormone', 'DNA Restriction Enzymes', 'Gene Expression Regulation', 'Genes', 'RNA, Messenger', 'Rats', 'Transcription, Genetic'] | 2,831,769 | [['B01.050'], ['E05.393.220'], ['D06.472.699.327.740.140', 'D12.644.400.400.740.140', 'D12.644.548.365.740.140', 'D12.776.631.650.405.740.140'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['G05.308'], ['G05.360.340.024.340'], ['D13.444.735.544'], ['B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Simple, rapid and efficient transformation of genotype Nisqually-1: a basic tool for the first sequenced model tree. | Genotype Nisqually-1 is the first model woody plant with an available well-annotated genome. Nevertheless, a simple and rapid transformation of Nisqually-1 remains to be established. Here, we developed a novel shoot regeneration method for Nisqually-1 using leaf petiole and stem segment explants. Numerous shoots formed... | ['Agrobacterium tumefaciens', 'Genetic Vectors', 'Genome, Plant', 'Genomics', 'Models, Biological', 'Plant Shoots', 'Plants, Genetically Modified', 'Regeneration', 'Transformation, Genetic', 'Trees'] | 28,572,673 | [['B03.440.400.425.700.024.050', 'B03.660.050.662.024.500'], ['G05.360.337'], ['G05.360.340.365'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['E05.599.395'], ['A18.024.875'], ['B01.650.520', 'B05.620.600'], ['G16.762'], ['G05.728.865'], ['B01.650.915']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Usefulness of imaging studies in prostate cancer: Analysis of 241 patients]. | BACKGROUND: The role of staging studies in patients with prostate cancer (PCa) is a topic of discussion.AIM: To evaluate the usefulness of imaging studies in patients with prostate cancer.MATERIAL AND METHODS: We reviewed the pathology service records to identify patients with prostate cancer diagnosed between 2003 and... | ['Humans', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Prostatic Neoplasms', 'Retrospective Studies', 'Risk Assessment'] | 28,898,333 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N... | ['Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Airway remodeling and inflammation in competitive swimmers training in indoor chlorinated swimming pools. | BACKGROUND: Airway disorders are common in regular chlorinated swimming pool attendees, particularly competitive athletes, but the impact of intense swimming training on airway function and structure remains unclear.OBJECTIVE: This study aimed to evaluate airway inflammation and remodeling in elite swimmers.METHODS: Tw... | ['Airway Remodeling', 'Allergens', 'Asthma', 'Bronchi', 'Bronchial Provocation Tests', 'Bronchoconstrictor Agents', 'Cell Count', 'Chlorine', 'Eosinophils', 'Female', 'Humans', 'Inflammation', 'Male', 'Mast Cells', 'Methacholine Chloride', 'Mucins', 'Neutrophils', 'Nitric Oxide', 'Skin Tests', 'Spirometry', 'Swimming',... | 22,196,771 | [['C23.300.017', 'G09.772.029'], ['D23.050.063'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['A04.411.125'], ['E01.370.386.700.125'], ['D27.505.696.663.050.100', 'D27.505.954.796.170'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['D01.268.380.150', 'D01.362.225... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 |
[Pathogenesis of diabetic lesions of the myocardium]. | On the basis of both literature data and their own observations, the authors suggest the identification of various forms of diabetic cardiopathy in relation to the pathogenetic mechanisms of the development of this complication. The microangiopathic form of diabetic cardiopathy develops as a result of cardiac diabetic ... | ['Animals', 'Autonomic Nervous System Diseases', 'Cardiomyopathies', 'Diabetes Complications', 'Diabetes Mellitus, Experimental', 'Diabetic Angiopathies', 'Diabetic Neuropathies', 'Humans', 'Myocardial Contraction', 'Myocardium'] | 6,492,578 | [['B01.050'], ['C10.177'], ['C14.280.238'], ['C19.246.099'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['C14.907.320', 'C19.246.099.500'], ['C10.668.829.300', 'C19.246.099.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.330.580', 'G11.427.494.570'], ['A02.633.580', 'A07.541.704', 'A10.690... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
2-deoxy-D-glucose modulation of T-lymphocyte reactivity: differential effects on lymphoid compartments. | This study was designed to evaluate the effect of glucoprivation, as induced by 2-deoxy-D-glucose (2-DG) administration, on lymphocyte mitogen reactivity in Sprague-Dawley rats. The results showed that a single injection of 2-DG decreased reactivity in both whole-blood and spleen lymphocytes, as determined by mitogenic... | ['Animals', 'Blood Glucose', 'Deoxy Sugars', 'Deoxyglucose', 'Leukocyte Count', 'Lymph Nodes', 'Male', 'Mitogens', 'Organ Specificity', 'Rats', 'Rats, Inbred Strains', 'Spleen', 'T-Lymphocytes', 'Thymus Gland'] | 3,266,559 | [['B01.050'], ['D09.947.875.359.448.500'], ['D09.254'], ['D09.254.229'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.107.595', 'G04.140.107.595', 'G09.188.105.595'], ['A10.549.400', 'A15.382.520.604.412'], ['D27.505.519.593.624'], ['G07.650']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Incidence and predictors of postoperative deep vein thrombosis in cardiac surgery in the era of aggressive thromboprophylaxis. | BACKGROUND: Deep venous thrombosis (DVT) is a well-known complication of surgery but its significance in cardiac surgery is not well defined. We reviewed the results of a prospective observational protocol for repeated postoperative lower extremity duplex venous scans (DVS) screening starting on postoperative day 3-4 t... | ['Aged', 'Cardiac Surgical Procedures', 'Female', 'Humans', 'Incidence', 'Leg', 'Male', 'Middle Aged', 'Prognosis', 'Prospective Studies', 'Thrombolytic Therapy', 'Ultrasonography', 'Venous Thrombosis'] | 20,732,491 | [['M01.060.116.100'], ['E04.100.376', 'E04.928.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['A01.378.610.500'], ['M01.060.116.630'], ['E01.789'], ['E05.318.372.500.750.625', 'N05.715.360.330.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inhibition of purified chicken gizzard smooth muscle ecto-ATPAse by P2 purinoceptor antagonists. | Several "specific" inhibitors of P2 purinergic receptors (purinoceptors) were evaluated for their ability to inhibit purified chicken gizzard cell membrane ecto-ATPase. The P2 purinoceptor antagonists tested included suramin, triazine based reactive textile dyes, and non-specific total protein dyes. All inhibited the p... | ['Adenosine Triphosphatases', 'Animals', 'Chickens', 'Coloring Agents', 'Enzyme Inhibitors', 'Gizzard, Avian', 'Muscle, Smooth', 'Purinergic P2 Receptor Antagonists', 'Suramin', 'Triazines'] | 7,581,008 | [['D08.811.277.040.025'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D27.720.233'], ['D27.505.519.389'], ['A13.853.355'], ['A02.633.570', 'A10.690.467'], ['D27.505.519.625.725.400.200', 'D27.505.696.577.725.400.200'], ['D02.455.426.559.847.638.555.750', 'D02.886.645.600.080.050.650.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical study of multiple zonal aganglionosis in long segment Hirschsprung's disease]. | OBJECTIVE: To discuss pathogeny and diagnosis and management of multiple zonal aganglionosis in Hirschsprung's disease.METHODS: Records of 3 children, aging 5 days, 29 days and 18 months, 3 boys, with multiple zonal aganglionosis in long segment Hirschsprung's disease between 1987-2005 were reviewed retrospectively. To... | ['Colon', 'Hirschsprung Disease', 'Humans', 'Ileum', 'Infant', 'Infant, Newborn', 'Male', 'Retrospective Studies'] | 16,324,319 | [['A03.556.124.526.356', 'A03.556.249.249.356'], ['C06.198.439', 'C06.405.469.158.701.439', 'C16.131.314.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684.249', 'A03.556.249.124'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.5... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cleaved lymphocytes in chronic lymphocytic leukemia: a detailed retrospective analysis of diagnostic features. | Through a global analysis of diagnostic features, the aim was to profile CLL patients with circulating cleaved lymphocytes at diagnosis, a controversial prognostic factor. Although some of them could have been considered today as having Non-Hodgkin's lymphoma, all 106 patients of our retrospective series have had CLL t... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antigens, CD', 'Cell Size', 'Female', 'Humans', 'Immunophenotyping', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Lymphocytes', 'Male', 'Middle Aged', 'Models, Biological', 'Multivariate Analysis', 'Prognosis', 'Retrospective Studies', 'Survival Rate'] | 12,002,759 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.050.301.264.035', 'D23.101.100.110'], ['G04.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.594.450'], ['C04.557.337.428.080.125', 'C15.604.515.560.080.125', 'C20.683.515.528.080.125'], ['A1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cytologic diagnosis of low-grade papillary urothelial neoplasms (low malignant potential and low-grade carcinoma) in the context of the 1998 WHO/ISUP classification. | The 1998 World Health Organization/International Society of Urological Pathology (WHO/ISUP) classification of urothelial neoplasms introduced a category called papillary neoplasm of low malignant potential (LMP) and separated it from low-grade papillary urothelial carcinoma (LGPUC), which was thought to yield abnormal ... | ['Carcinoma, Papillary', 'Carcinoma, Transitional Cell', 'Humans', 'Retrospective Studies', 'Sensitivity and Specificity', 'Urinalysis', 'Urinary Bladder Neoplasms', 'Urine', 'Urothelium', 'World Health Organization'] | 12,672,093 | [['C04.557.470.200.360', 'C04.557.470.700.360'], ['C04.557.470.200.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ['E05.318.370.800... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Drivers' and cyclists' experiences of sharing the road: incidents, attitudes and perceptions of visibility. | This study explored the beliefs and attitudes of cyclists and drivers regarding cyclist visibility, use of visibility aids and crashes involving cyclists and motorists. Data are presented for 1460 participants (622 drivers and 838 cyclists) and demonstrate that there are high rates of cyclist-vehicle crashes, many of w... | ['Accidents, Traffic', 'Adult', 'Automobile Driving', 'Bicycling', 'Data Collection', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Location Directories and Signs', 'Male', 'Middle Aged', 'Odds Ratio', 'Social Perception', 'Visual Perception'] | 19,540,966 | [['N06.850.135.392'], ['M01.060.116'], ['I03.125'], ['I03.450.642.845.140'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.086.339.400'], ['M01.060.116.630'], ['E05.318.740.600.600', 'G17.680.500', 'N0... | ['Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Process... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 |
[New possibilities of treating acute angioedema caused by C1-inhibitor deficiency]. | The authors discuss diagnostic difficulties in 12 cases of hereditary angioneurotic edema due to C1-esterase inhibitor (C1-INH deficiency). Emphasis is on the treatment of the acute attacks with intravenous infusions of C1-inhibitor concentrate (Boehring, West Germany). This proved to be a very efficient and safe thera... | ['Acute Disease', 'Adolescent', 'Adult', 'Angioedema', 'Complement C1 Inactivator Proteins', 'Female', 'Humans', 'Liver Function Tests', 'Male', 'Middle Aged'] | 2,637,436 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['C14.907.079', 'C17.800.862.945.066', 'C20.543.480.904.066'], ['D12.644.861.140', 'D12.776.124.486.274.920.250', 'D12.776.872.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.372.460'], ['M01.060.116.630']] | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Quantitative assessment of cutaneous erythema]. | On the basis of general concepts on the objective nature of colour perception and colourimetric tables of the colour atlas special colourimetric rulers were elaborated for the assessment of skin erythema. These rulers can be used for the assessment of experimentally-reproduced common and allergic inflammations of the s... | ['Animals', 'Erythema', 'Guinea Pigs', 'Methods'] | 851,626 | [['B01.050'], ['C17.800.229', 'C23.888.885.328'], ['B01.050.150.900.649.313.992.550'], ['E05.581']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stromal progenitor cells from endogenous adipose tissue contribute to pericytes and adipocytes that populate the tumor microenvironment. | Epidemiologic studies associate cancer with obesity, but the pathophysiologic connections remain obscure. In this study, we show that obesity facilitates tumor growth in mice irrespective of concurrent diet, suggesting a direct effect of excess white adipose tissue (WAT). When transplanted into mice, adipose stromal ce... | ['Adipocytes', 'Adipose Tissue', 'Animals', 'Bone Marrow Transplantation', 'Flow Cytometry', 'Mice', 'Mice, Inbred C57BL', 'Obesity', 'Pericytes', 'Stem Cells', 'Stromal Cells', 'Tumor Microenvironment'] | 23,071,132 | [['A11.329.114'], ['A10.165.114'], ['B01.050'], ['E02.095.147.725.040', 'E04.936.580.040'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.05... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The relation between depth of trophoblastic invasion and beta-HCG levels in tubal pregnancies. | beta-HCG (human chorionic gonadotropin) values of over 2500 I.U./l are associated with higher failure rates for therapy with prostaglandin F2 alpha in tubal pregnancies. The purpose of our study was to ascertain if the 2500 I.U./l limit correlates with histopathology. We therefore compared the pre-operative beta-HCG-va... | ['Chorionic Gonadotropin', 'Chorionic Gonadotropin, beta Subunit, Human', 'Dinoprost', 'Fallopian Tubes', 'Female', 'Humans', 'Peptide Fragments', 'Pregnancy', 'Pregnancy, Tubal', 'Treatment Outcome', 'Trophoblasts'] | 7,541,981 | [['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['D06.472.699.322.326.125', 'D06.472.699.649.367.125', 'D12.644.548.726.367.125', 'D12.776.780.400.125', 'D23.101.140.325', 'D23.101.175'], ['D10.251.355.255.550.400.200', 'D23.469.050.175.725.400.200'], ['A05.360.319.114.373', '... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The pharmacokinetics of sertraline excretion into human breast milk: determinants of infant serum concentrations. | BACKGROUND: The purpose of this study was to attain a new landmark in the area of selective serotonin reuptake inhibitor therapy during lactation by establishing a basis for interpreting infant serum concentrations and for minimizing infant exposure in the absence of treatment-emergent side effects.METHOD: Breast milk ... | ['Breast Feeding', 'Child Development', 'Chromatography, High Pressure Liquid', 'Depressive Disorder', 'Female', 'Humans', 'Infant, Newborn', 'Lactation', 'Milk, Human', 'Pregnancy', 'Serotonin Uptake Inhibitors', 'Sertraline'] | 12,590,627 | [['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['F01.525.200', 'G07.345.374.750'], ['E05.196.181.400.300'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['G08.686.523', 'G08.686.702.500'], ['A12.200.467', 'A12.790.500', 'G07.203.100.7... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
The serum lathosterol to cholesterol ratio, an index of cholesterol synthesis, is not elevated in patients with glomerular proteinuria and is not associated with improvement of hyperlipidemia in response to antiproteinuric treatment. | The hypothesis that increased cholesterol synthesis provides a mechanism that contributes to nephrotic syndrome-associated hyperlipidemia is mainly based on experimental evidence. The serum level of the cholesterol precursor, lathosterol (expressed per millimole cholesterol), is a reliable marker of whole-body choleste... | ['Angiotensin-Converting Enzyme Inhibitors', 'Cholesterol', 'Dietary Proteins', 'Glomerulonephritis', 'Humans', 'Hyperlipidemias', 'Isomerism', 'Proteinuria'] | 8,637,447 | [['D27.505.519.389.745.085'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['C12.777.419.570.363', 'C13.351.968.419.570.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.584.500.500'], ['G02.111.570.685', 'G02.607.445'], ['... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent. | We have recently reported that a 16-amino acid long polypeptide corresponding to the third helix of the DNA binding domain (homeodomain) of Antennapedia, a Drosophila transcription factor, is internalized by cells in culture (Derossi, D., Joliot, A. H., Chassaing, G., and Prochiantz, A.(1994) J. Biol. Chem. 269, 10444-... | ['Amino Acid Sequence', 'Animals', 'Antennapedia Homeodomain Protein', 'Biological Transport', 'Cell Membrane', 'Cells, Cultured', 'Corpus Striatum', 'Homeodomain Proteins', 'Models, Biological', 'Models, Molecular', 'Molecular Sequence Data', 'Neurons', 'Nuclear Proteins', 'Peptide Fragments', 'Protein Structure, Seco... | 8,663,410 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.260.400.124', 'D12.776.660.049', 'D12.776.930.120'], ['G03.143'], ['A11.284.149'], ['A11.251'], ['A08.186.211.200.885.287.249.487'], ['D12.776.260.400'], ['E05.599.395'], ['E05.599.595'], ['L01.453.245.667'], ['A08.675', 'A11.671'], ['D12.776.660'], ['... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Small-molecule fluorescent probes for specific RNA targets. | A method was developed that uses small molecules as fluorescent probes to detect specific mRNAs. In this approach, the fluorescence of fluorophore-quencher conjugates is restored by the binding of an mRNA aptamer tag to the quencher segment of the molecules. The method allows real-time detection of mRNA transcripts in ... | ['Aptamers, Nucleotide', 'Fluorescent Dyes', 'Molecular Structure', 'Molecular Weight', 'RNA, Messenger'] | 21,412,566 | [['D13.695.578.424.224'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['G02.111.570', 'G02.466'], ['G02.494'], ['D13.444.735.544']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studies on N1-DNCP-N6-lactobionoyl-1,6-hexanediamine--a distinctive monovalent anaphylactogen. | N1-DNCP-N6-lactobionoyl-1,6,hexanediamine, which is a potent anaphylactogen when i.v. injected into anti-DNCP sensitized guinea pigs, was shown to be also anaphylactogenic when administered intradermally into guinea pigs passively sensitized by i.v. injection of anti-DNCP antiserum. The compound, which is monohaptenic ... | ['Animals', 'Disaccharides', 'Guinea Pigs', 'Haptens', 'Immunochemistry', 'Passive Cutaneous Anaphylaxis'] | 4,077,350 | [['B01.050'], ['D09.698.629.305', 'D09.947.750'], ['B01.050.150.900.649.313.992.550'], ['D23.050.550.480'], ['H01.158.201.486', 'H01.181.122.605', 'H02.403.044.500'], ['E01.370.225.812.871.600', 'E05.200.812.871.600', 'E05.478.594.890.600', 'G12.122.754']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Voltage-activated potassium, but not calcium currents in cultured bovine aortic endothelial cells. | The electrophysiological properties of cultured bovine aortic endothelial cells were characterized using the patch clamp technique. Resting potentials were measured on passing to the whole cell recording configuration and were close to--65 mV in healthy cells. In cell-attached recordings with a high potassium pipette s... | ['Animals', 'Cattle', 'Cells, Cultured', 'Endothelium, Vascular', 'Ion Channels', 'Membrane Potentials'] | 2,448,738 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['A07.015.700.500', 'A10.272.491.355'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
"PROPAGANDISTS FOR THE BEHAVIORAL SCIENCES": THE OVERLOOKED PARTNERSHIP BETWEEN THE CARNEGIE CORPORATION AND SSRC IN THE MID-TWENTIETH CENTURY. | The Carnegie Corporation's role as a patron of the behavioral sciences has been overlooked; its support for the behavioral sciences not only began earlier than the Ford Foundation's but was also at least equally important to their success. I show how the close postwar collaboration between the Carnegie Corporation and ... | ['Behavioral Research', 'Behavioral Sciences', 'Foundations', 'History, 20th Century', 'Humans', 'Interinstitutional Relations', 'Social Sciences', 'United States'] | 26,938,307 | [['F04.096.144', 'H01.770.644.108'], ['F04.096'], ['N03.219.483.311', 'N03.540.630.180'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.822.400'], ['F04.096.879', 'I01'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Humanities [K]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Effects of counter cations of base catalysts on nitrosation mechanisms. | Reaction of 2-butanone (1) with tert-butyl nitrite (tert-BuONO) was performed using base catalysts (RO-M+: R=CH3, C2H5; M+=Li+, Na+, K+) in alcohols (CH3OH or C2H5OH). In this report, the effects of M+ of RO-M+ on the nitrosation mechanisms were investigated. The yield of E-hydroxyimino compound (5E) increases much bet... | ['Catalysis', 'Cations', 'Electrons', 'Ethers, Cyclic', 'Gas Chromatography-Mass Spectrometry', 'Nitroso Compounds'] | 11,767,092 | [['G02.130'], ['D01.248.497.300'], ['G01.249.335', 'G01.358.500.750'], ['D02.355.291', 'D04.345.241'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D02.654']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Arsenic removal from flooded paddy soil with spontaneous hygrophyte markedly attenuates rice grain arsenic. | China ranks the top in global annual rice output. However, extensive mining and smelting has led to elevated arsenic (As) in paddy soils, potentially imperiling local population health and sustainable rice production in the country. Under flooded condition, reductive As mobilization generally occurs, providing a unique... | ['Arsenic', 'Arsenicals', 'China', 'Edible Grain', 'Floods', 'Oryza', 'Soil', 'Soil Pollutants'] | 31,521,815 | [['D01.268.513.249'], ['D01.075', 'D02.129'], ['Z01.252.474.164'], ['A18.024.500.750.500', 'B01.650.160.250', 'B01.650.510.250', 'G07.203.300.300.550', 'G07.203.300.775.500', 'J02.500.300.550', 'J02.500.775.500'], ['G16.500.175.812', 'N06.230.100.230.250'], ['B01.650.940.800.575.912.250.822.616'], ['D20.721', 'G01.311.... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Retrieval activates related words more than presentation. | Retrieving information enhances learning more than restudying. One explanation of this effect is based on the role of mediators (e.g., sand-castle can be mediated by beach). Retrieval is hypothesised to activate mediators more than restudying, but existing tests of this hypothesis have had mixed results [Carpenter, S. ... | ['Adolescent', 'Adult', 'Association', 'Cues', 'Female', 'Humans', 'Male', 'Mental Recall', 'Practice, Psychological', 'Recognition, Psychology', 'Repetition Priming', 'Semantics', 'Word Association Tests', 'Young Adult'] | 29,571,266 | [['M01.060.057'], ['M01.060.116'], ['F02.463.425.069', 'F04.754.720.346'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['F02.463.425.674'], ['F02.463.425.540.706'], ['F02.463.425.540.739'], ['L01.559.598.745'], ['F04.711.647.905'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Effects of dog-assisted intervention on behavioural and psychological symptoms of dementia. | AIM: To evaluate the effect of a dog-assisted intervention on the behavioural and psychological symptoms of residents with dementia during a six-month period.METHOD: The study was conducted in eight nursing homes in Sweden. A total of 33 residents with dementia, 20 in the intervention group and 13 in the control group,... | ['Aged', 'Aged, 80 and over', 'Animal Assisted Therapy', 'Animals', 'Case-Control Studies', 'Dementia', 'Dogs', 'Female', 'Human-Animal Bond', 'Humans', 'Male', 'Middle Aged', 'Nursing Homes', 'Sweden'] | 24,673,326 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.760.169.063.500.083', 'E02.779.124', 'F04.754.017'], ['B01.050'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.750.250.216.200'], ['F01.145.496.500'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
SOCS-1 Suppresses Inflammation Through Inhibition of NALP3 Inflammasome Formation in Smoke Inhalation-Induced Acute Lung Injury. | Smoke inhalation leads to acute lung injury (ALI), a devastating clinical problem associated with high mortality rates. Suppressor of cytokine signaling-1 (SOCS-1) is a negative regulator of proinflammatory cytokine signaling. We have found that adenoviral gene transfer of SOCS-1 ameliorates smoke inhalation-induced lu... | ['Acute Lung Injury', 'Animals', 'Inflammasomes', 'Mice', 'Mice, Inbred C57BL', 'NLR Family, Pyrin Domain-Containing 3 Protein', 'Pneumonia', 'Smoke', 'Suppressor of Cytokine Signaling 1 Protein', 'Suppressor of Cytokine Signaling Proteins'] | 29,907,905 | [['C08.381.520.500'], ['B01.050'], ['D05.500.224'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D12.644.360.539.250'], ['C01.748.610', 'C08.381.677', 'C08.730.610'], ['D20.633.937'], ['D12.644.360.024.374.500', 'D12.776.157.057.249.5... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interlaboratory evaluation of the C3H/10T1/2 cell transformation assay. | The C3H/10T1/2 transformation assay was evaluated for its responsiveness and interlaboratory reproducibility. Two laboratories participated in this study and tested a series of 46 chemicals. The majority of these chemicals were tested under code. Of the 46 chemicals tested, seven were determined to be active in both la... | ['Animals', 'Cell Line', 'Cell Transformation, Neoplastic', 'Fibroblasts', 'Mice', 'Mice, Inbred C3H'] | 3,383,839 | [['B01.050'], ['A11.251.210'], ['C04.697.098.500', 'C23.550.727.098.500'], ['A11.329.228'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.388', 'B01.050.150.900.649.313.992.635.505.500.400.388']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Perceived racial discrimination in health care: a comparison of Veterans Affairs and other patients. | OBJECTIVES: We compared rates of perceived racial discrimination in health care settings for veteran and nonveteran patients and for veterans who used the Veterans Affairs health care system and those who did not.METHODS: Data were drawn from the 2004 Behavioral Risk Factor Surveillance System. We used logistic regress... | ['Adolescent', 'Adult', 'Aged', 'Behavioral Risk Factor Surveillance System', 'Delivery of Health Care', 'Female', 'Humans', 'Male', 'Middle Aged', 'Odds Ratio', 'Prejudice', 'United States', 'United States Department of Veterans Affairs', 'Young Adult'] | 19,443,818 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.308.980.438.149', 'N05.715.360.300.800.438.149', 'N06.850.520.308.980.438.149'], ['N04.590.374', 'N05.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.625.590', 'N06.850.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Efficacy of Seprafilm® in abdominal surgery for ventriculoperitoneal shunt malfunction: a report of two pediatric cases. | Temporary external drainage with adequate antibiotic treatment followed by ventriculoperitoneal (VP) shunt reinsertion is necessary to treat VP shunt malfunction with infection. In surgeries for VP shunt reinsertion, the key factors that determine whether the reinserted VP shunt will function sufficiently are adequate ... | ['Abdominal Cavity', 'Female', 'Humans', 'Hyaluronic Acid', 'Hydrocephalus', 'Male', 'Membranes, Artificial', 'Reoperation', 'Tissue Adhesions', 'Ventriculoperitoneal Shunt'] | 22,041,544 | [['A01.923.047.025'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.475'], ['C10.228.140.602'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['E04.690'], ['C23.550.355.274.840'], ['E04.035.188.850', 'E04.525.170.850']] | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Elimination of poisons]. | Therapeutic methods for treating poisoned men are based on the principles of intensive care therapy. The elimination of toxins depends on the circulatory circumstances; an enhancement of poison elimination can be achieved in providing a normal circulation. In the treatment of most cases of poisoning gastric and gut lav... | ['Bicarbonates', 'Carbon Dioxide', 'Electrolytes', 'Furosemide', 'Gastric Lavage', 'Hemoperfusion', 'Humans', 'Hydrogen-Ion Concentration', 'Mannitol', 'Poisoning', 'Renal Dialysis', 'Respiratory Therapy'] | 6,818,774 | [['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D01.248'], ['D02.065.884.725.300', 'D02.092.146.807.300', 'D02.886.590.700.725.300'], ['E05.927.441'], ['E02.870.244', 'E02.912.430', 'E04.292.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thermodynamic role of the pro region of the neurophysin precursor in neurophysin folding: evidence from the effects of ligand peptides on folding. | Attention has focused recently on the role of amino-terminal precursor pro regions in protein folding, with particular emphasis on their effects on folding kinetics. We examined the kinetic and thermodynamic effects of ligand peptides on the folding of neurophysin from the reduced state; these peptides serve as analogs... | ['Animals', 'Cattle', 'Disulfides', 'Glutathione', 'Hydrogen-Ion Concentration', 'Ligands', 'Neurophysins', 'Oxidation-Reduction', 'Protein Folding', 'Protein Precursors', 'Thermodynamics'] | 8,547,267 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['D12.644.456.448'], ['G02.300'], ['D27.720.470.480'], ['D12.644.400.525', 'D12.776.157.597', 'D12.776.631.650.525'], ['G02.700', 'G03.295.531'], ['G01.154.651', 'G02.111.688'], ['D12.776.811'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Co-delivery of siRNA and etoposide to cancer cells using an MDEA esterquat based drug delivery system. | Cancer has become the leading cause of death in many countries. Chemotherapy is a key component in the treatment of most cancers but has limited efficacy if the cancer develops resistance to the treatment over time and recur. RNA interference may be used to reduce the production of the proteins responsible for chemothe... | ['Antineoplastic Agents, Phytogenic', 'Cell Line, Tumor', 'Combined Modality Therapy', 'Drug Delivery Systems', 'Etoposide', 'Gene Silencing', 'Green Fluorescent Proteins', 'Humans', 'Neoplasms', 'Quaternary Ammonium Compounds', 'RNA, Small Interfering'] | 30,409,750 | [['D27.505.954.248.179'], ['A11.251.210.190', 'A11.251.860.180'], ['E02.186'], ['E02.319.300'], ['D02.455.426.559.847.638.960.675.250', 'D04.615.638.960.675.250', 'D09.408.348.275'], ['G05.308.203.374'], ['D12.776.532.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['D01.625.062.500', 'D02.092.877', 'D... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitative, noninvasive assessment of antidiarrheal actions of codeine using an experimental model of diarrhea in man. | Enteric coating of a capsule has been used to deliver a bolus of radioisotope to the ileocecal region. This has allowed quantitative assessment of regional colonic transit in a group of healthy subjects whose proximal colonic transit was accelerated by lactulose 20 ml thrice daily. In this experimental model of diarrhe... | ['Adult', 'Capsules', 'Codeine', 'Colon', 'Diarrhea', 'Female', 'Gastrointestinal Transit', 'Humans', 'Lactulose', 'Male', 'Particle Size', 'Radionuclide Imaging', 'Sodium Pertechnetate Tc 99m', 'Tablets, Enteric-Coated', 'Time Factors'] | 8,389,688 | [['M01.060.116'], ['D26.255.150'], ['D03.132.577.249.562.149', 'D03.605.497.607.204', 'D03.633.400.686.607.204', 'D04.615.723.795.576.149'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C23.888.821.214'], ['E01.370.372.310', 'G10.261.360.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.629.305.423... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adsorptive refolding of a highly disulfide-bonded inclusion body protein using anion-exchange chromatography. | alpha-Fetoprotein (AFP) is a prospective biopharmaceutical candidate currently undergoing advanced-stage clinical trials for autoimmune indications. The high AFP expression yields in the form of inclusion bodies in Escherichia coli renders the inclusion body route potentially advantageous for process scale commercial m... | ['Adsorption', 'Chromatography, Ion Exchange', 'Disulfides', 'Escherichia coli', 'Gene Expression', 'Humans', 'Inclusion Bodies', 'Protein Folding', 'Recombinant Proteins', 'alpha-Fetoproteins'] | 19,419,725 | [['G01.030', 'G02.020'], ['E05.196.181.400.383'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.420'], ['G01.154.651', 'G02.111.688'], ['D12.776.828'], ['D12.776.124.7... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Advanced psychotherapy training: psychotherapy scholars' track, and the apprenticeship model. | BACKGROUND/OBJECTIVE: Guided by ACGME's requirements, psychiatric residency training in psychotherapy currently focuses on teaching school-specific forms of psychotherapy (i.e., cognitive-behavioral, supportive, and psychodynamic psychotherapy). On the basis of a literature review of common factors affecting psychother... | ['Clinical Competence', 'Cognitive Behavioral Therapy', 'Curriculum', 'Humans', 'Internship and Residency', 'Pilot Projects', 'Problem-Based Learning', 'Psychiatry', 'Psychotherapeutic Processes', 'Psychotherapy', 'Psychotherapy, Brief', 'Psychotherapy, Psychodynamic'] | 23,820,910 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['F04.754.137.350'], ['I02.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['F02.463.425.720', 'I02.158.660', 'I02.903.565'], ['F0... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Evaluation of therapeutic anticoagulation with enoxaparin and associated anti-Xa monitoring in patients with morbid obesity: a case series. | Our purpose was to describe anti-Xa levels, dosage requirements, and complications associated with enoxaparin treatment doses in patients with morbid obesity. Inpatients with a BMI >40 kg/m(2) at an academic medical center prescribed therapeutic enoxaparin from 2004 to 2010 who also had an associated anti-Xa level were... | ['Adult', 'Aged', 'Blood Coagulation Factor Inhibitors', 'Enoxaparin', 'Evaluation Studies as Topic', 'Factor Xa Inhibitors', 'Female', 'Fibrinolytic Agents', 'Hemorrhage', 'Humans', 'Male', 'Middle Aged', 'Monitoring, Physiologic', 'Obesity, Morbid', 'Retrospective Studies', 'Venous Thromboembolism'] | 21,465,129 | [['M01.060.116'], ['M01.060.116.100'], ['D23.113'], ['D09.698.373.400.300.200'], ['E05.337', 'N05.715.360.335'], ['D27.505.519.389.745.800.449.500', 'D27.505.954.502.119.500.500'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Plasmin-mediated activation of the coagulation system. A study of patients with acute ischemic heart disease treated with recombinant tissue-plasminogen activator]. | We have studied the response of haemostatic reaction products in peripheral blood of patients with acute ischaemic heart disease receiving combined recombinant tissue type plasminogen activator/heparin therapy. We have found evidence that formation of excessive amounts of plasmin in vivo in relation to such therapy sig... | ['Acute Disease', 'Blood Coagulation', 'Fibrin Fibrinogen Degradation Products', 'Fibrinolysin', 'Humans', 'Myocardial Ischemia', 'Prospective Studies', 'Thrombolytic Therapy', 'Tissue Plasminogen Activator'] | 8,009,715 | [['C23.550.291.125'], ['G09.188.390.150'], ['D12.776.124.270.300', 'D12.776.811.300.290'], ['D08.811.277.656.300.760.330', 'D08.811.277.656.959.350.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.647', 'C14.907.585'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of digitonin on hyperglycaemia and dyslipidemia induced by high-sucrose intake. | This study examined whether high-sucrose intake effects on lipid profile and oral glucose tolerance may be inhibited by a single administration of digitonin, a saponin from the seeds of Digitalis purpurea Male Wistar 24 rats were initially divided into two groups (n=12): (C) was given standard chow and water; (S) recei... | ['Animals', 'Blood Glucose', 'Body Weight', 'Cholesterol', 'Cholesterol, VLDL', 'Diet', 'Digitonin', 'Dyslipidemias', 'Eating', 'Energy Metabolism', 'Fatty Acids, Nonesterified', 'Glucose Intolerance', 'Glucose Tolerance Test', 'Hyperglycemia', 'Lipid Peroxidation', 'Lipids', 'Male', 'Organ Size', 'Rats', 'Rats, Wistar... | 16,112,785 | [['B01.050'], ['D09.947.875.359.448.500'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.247', 'D10.532.599.700', 'D10.570.938.208.285', 'D12.776.52... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
UV-radiation-induced internalization of the epidermal growth factor receptor requires distinct serine and tyrosine residues in the cytoplasmic carboxy-terminal domain. | The mechanism of UV-radiation-induced EGF receptor (EGFR) internalization remains to be established. In the present study, we found UV-radiation-mediated internalization of the EGFR to be dependent on the cytoplasmic carboxy-terminal region. UV radiation was unable to induce internalization of EGFR carboxy-terminal tru... | ['Amino Acid Sequence', 'Animals', 'Cytoplasm', 'Dose-Response Relationship, Radiation', 'ErbB Receptors', 'Mice', 'Molecular Sequence Data', 'Mutation', 'NIH 3T3 Cells', 'Platelet-Derived Growth Factor', 'Protein Conformation', 'Protein Transport', 'Serine', 'Structure-Activity Relationship', 'Tissue Distribution', 'T... | 15,161,351 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.284.430.214'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['B01.050.150.900.649.313.992.635.505.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Evaluation of a successful biosocial rotation. | Efficacy of an eight-week rotation in developmental and behavioral pediatrics for second-year pediatric residents was evaluated. Pretesting and posttesting disclosed that our residents felt more competent with biosocial problems, had more favorable attitudes toward patients with biosocial problems, and had increased fa... | ['Arizona', 'Attitude of Health Personnel', 'Child', 'Child Abuse', 'Child Care', 'Curriculum', 'Humans', 'Internship and Residency', 'Pediatrics', 'Physician-Patient Relations', 'Psychology, Child'] | 6,637,908 | [['Z01.107.567.875.760.100'], ['F01.100.050', 'N05.300.100'], ['M01.060.406'], ['I01.198.240.856.350.250', 'I01.880.735.900.350.250'], ['I01.880.787.293.360', 'N02.421.088'], ['I02.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['H02.403.670'], ['F01.829.401.650.... | ['Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Deubiquitinating enzyme USP30 maintains basal peroxisome abundance by regulating pexophagy. | The regulation of organelle abundance is critical for cell function and survival; however, the mechanisms responsible are not fully understood. In this study, we characterize a role of the deubiquitinating enzyme USP30 in peroxisome maintenance. Peroxisomes are highly dynamic, changing in abundance in response to metab... | ['Animals', 'COS Cells', 'Chlorocebus aethiops', 'HeLa Cells', 'Humans', 'Mice', 'Mitochondrial Proteins', 'Mitophagy', 'Mutation', 'Peroxisomal Biogenesis Factor 2', 'Peroxisomes', 'Stress, Physiological', 'Thiolester Hydrolases'] | 30,700,497 | [['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.575'], ['G04.011.937', 'G04.599.500'],... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of maternal western-style diet on amniotic fluid volume and amnion VEGF profiles in a nonhuman primate model. | During pregnancy, high fat diet (HFD) induces maternal obesity, insulin resistance, and placental inflammatory responses that compromise placental and fetal development. Whether maternal HFD would adversely affect amniotic fluid volume (AFV) has not been explored. Vascular endothelial growth factor (VEGF) is expressed ... | ['Amnion', 'Amniotic Fluid', 'Animals', 'Diet, High-Fat', 'Female', 'Macaca', 'Male', 'Maternal Nutritional Physiological Phenomena', 'Pregnancy', 'Vascular Endothelial Growth Factor A', 'Vascular Endothelial Growth Factor Receptor-1'] | 30,353,684 | [['A10.615.284.277', 'A16.254.750.277'], ['A12.098', 'A16.378.149'], ['B01.050'], ['G07.203.650.240.267'], ['B01.050.150.900.649.313.988.400.112.199.120.510'], ['G07.203.650.566'], ['G08.686.784.769'], ['D12.644.276.100.800.200', 'D12.776.467.100.800.200', 'D23.529.100.800.200'], ['D08.811.913.696.620.682.725.400.950.1... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Self-assembled templates for polypeptide synthesis. | The chemical synthesis of polypeptide chains >50 amino acids with prescribed sequences is challenging. In one approach, native chemical ligation (NCL), short, unprotected peptides are connected through peptide bonds to render proteins in water. Here we combine chemical ligation with peptide self-assembly to deliver ext... | ['Amino Acid Sequence', 'Molecular Sequence Data', 'Molecular Structure', 'Particle Size', 'Peptides'] | 17,949,087 | [['G02.111.570.060', 'L01.453.245.667.060'], ['L01.453.245.667'], ['G02.111.570', 'G02.466'], ['G02.712'], ['D12.644']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Size and Proportions of Slow-Twitch and Fast-Twitch Muscle Fibers in Human Costal Diaphragm. | Smaller diaphragmatic motor unit potentials (MUPs) compared to MUPs of limb muscles lead to the hypothesis that diaphragmatic muscle fibers, being the generators of MUPs, might be also smaller. We compared autopsy samples of costal diaphragm and vastus lateralis of healthy men with respect to fibers' size and expressio... | ['Adult', 'Cadaver', 'Cell Count', 'Diaphragm', 'Humans', 'Male', 'Middle Aged', 'Muscle Fibers, Fast-Twitch', 'Muscle Fibers, Slow-Twitch', 'Ribs'] | 27,891,518 | [['M01.060.116'], ['C23.550.260.224'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A02.633.567.900.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A10.690.552.500.500.600', 'A11.620.249.400'], ['A10.690.552.500.500.700', 'A11.620.249.700'], ['A02.835.232.570.50... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Palmitic acid-labeled lipids selectively incorporated into platelet cytoskeleton during aggregation. | Previous experiments showed that during the early stages (20-30 seconds) of aggregation induced by adenosine diphosphate (ADP, 2 microM) or thrombin (0.1 U/mL) of rabbit or human platelets prelabeled with [3H]palmitic acid, labeled lipid became associated with the cytoskeleton isolated after lysis with 1% Triton X-100,... | ['Animals', 'Ceramides', 'Chromatography, Liquid', 'Cytoskeleton', 'Humans', 'Lipids', 'Palmitic Acid', 'Palmitic Acids', 'Phospholipids', 'Platelet Aggregation', 'Rabbits', 'Tritium'] | 2,395,415 | [['B01.050'], ['D02.065.313', 'D09.400.410.420.525.200', 'D10.390.470.675.200', 'D10.570.877.360.612.200'], ['E05.196.181.400'], ['A11.284.430.214.190.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10'], ['D10.251.694.750'], ['D10.251.694'], ['D10.570.755'], ['G09.188.370.687', 'G09.188.390.600.640'], ['B01... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interpopulational differences in the concentrations and ratios of salivary and serum progesterone. | Lower concentrations of salivary P in Bolivian women cannot be attributed to lower serum P or cholesterol or to higher cortisol-binding globulin or cortisol (stress) levels than those of the American women. Whether serum or salivary concentrations in the two population groups better reflect availability of P to the tis... | ['Bolivia', 'Humans', 'Hydrocortisone', 'Progesterone', 'Reproducibility of Results', 'Saliva', 'Sensitivity and Specificity', 'United States'] | 16,828,474 | [['Z01.107.757.136'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['D04.210.500.745.745.654.829', 'D06.472.334.734.623', 'D06.472.334.851.687.750'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'... | ['Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Why don't key populations access HIV testing and counselling centres in Nepal? Findings based on national surveillance survey. | OBJECTIVES: To assess the demographic, behavioural, psychosocial and structural factors associated with non-utilisation of HIV testing and counselling (HTC) services by female sex workers (FSWs) and men who have sex with men/transgender (MSM/TG).METHODS: This study involved a cross-sectional design. We used the nationa... | ['Adolescent', 'Adult', 'Counseling', 'Cross-Sectional Studies', 'Depression', 'Female', 'HIV Infections', 'Homosexuality, Male', 'Humans', 'Male', 'Mass Screening', 'Nepal', 'Regression Analysis', 'Sex Workers', 'Suicidal Ideation', 'Transgender Persons', 'Young Adult'] | 29,288,177 | [['M01.060.057'], ['M01.060.116'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.126.350'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.67... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Three-dimensional reconstruction of coronary arteries and plaque morphology using CT angiography--comparison and registration with IVUS. | BACKGROUND: The aim of this study is to present a new methodology for three-dimensional (3D) reconstruction of coronary arteries and plaque morphology using Computed Tomography Angiography (CTA).METHODS: The methodology is summarized in six stages: 1) pre-processing of the initial raw images, 2) rough estimation of the... | ['Algorithms', 'Coronary Angiography', 'Coronary Vessels', 'Humans', 'Imaging, Three-Dimensional', 'Plaque, Atherosclerotic', 'Tomography, X-Ray Computed', 'Ultrasonography, Interventional'] | 26,785,613 | [['G17.035', 'L01.224.050'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['A07.015.114.269', 'A07.015.908.194'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['C23.300.823'], ['E01.370.350.350.810', 'E01.370.350.600.350.70... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Peptide YY and gallbladder contraction. Studies in vivo and in vitro. | The purpose of this study was to examine the effect of peptide YY on contraction of the gallbladder in vivo and in vitro and on contraction of the sphincter of Oddi in vitro. In conscious dogs that were prepared with strain-gauge force transducers implanted in the gallbladder wall, peptide YY (400 ng/kg, bolus; 800 pmo... | ['Ampulla of Vater', 'Animals', 'Dogs', 'Female', 'Gallbladder', 'Gastrointestinal Hormones', 'In Vitro Techniques', 'Male', 'Muscle Contraction', 'Muscle, Smooth', 'Peptide YY', 'Peptides', 'Proglumide', 'Sincalide', 'Sphincter of Oddi'] | 3,360,265 | [['A03.159.183.079.300.950', 'A03.556.124.684.124.236', 'A03.556.875.249.160', 'A03.734.667.500'], ['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['A03.159.439'], ['D06.472.317'], ['E05.481'], ['G11.427.494'], ['A02.633.570', 'A10.690.467'], ['D06.472.317.662', 'D06.472.699.595', 'D12.644.548.595'], ['D12.64... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Accepting adoption's uncertainty: the limited ethics of pre-adoption genetic testing. | An increasing number of children are adopted in the United States from countries where both medical care and environmental conditions are extremely poor. In response to worries about the accuracy of medical histories, prospective adoptive parents increasingly request genetic testing of children prior to adoption. Thoug... | ['Adoption', 'Child', 'Child Welfare', 'Developing Countries', 'Genetic Testing', 'Humans', 'Parents', 'Risk', 'Uncertainty', 'United States'] | 24,913,138 | [['I01.880.853.150.140'], ['M01.060.406'], ['I01.880.787.293'], ['I01.615.500.300'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E05.318.740.600.800', 'G17.6... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
In vitro and in vivo assessment of matrix type transdermal therapeutic system of labetalol hydrochloride. | OBJECTIVE: The aim of the investigation was to develop and evaluate matrix type transdermal therapeutic systems containing new polymeric combinations (Eudragit E PO/Eudragit RL 100 & Plasdone S 630) as polymers and Labetalol Hydrochloride (LBHCl) as a model drug.EXPERIMENTAL: The matrix type TTS of LBHCl were prepared ... | ['Administration, Cutaneous', 'Animals', 'Antihypertensive Agents', 'Blood Pressure', 'Delayed-Action Preparations', 'Drug Delivery Systems', 'Elasticity', 'Humans', 'In Vitro Techniques', 'Labetalol', 'Models, Biological', 'Permeability', 'Polymers', 'Rats', 'Rats, Wistar', 'Skin', 'Skin Irritancy Tests', 'Solubility'... | 19,863,491 | [['E02.319.267.120.060'], ['B01.050'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D26.255.210', 'E02.319.300.253'], ['E02.319.300'], ['G01.374.590'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D02.033.100.291.460', 'D02.065.793.324', 'D02.092.063.291.460'], ['E05.599.395... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.