Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Tannin-protein complexes as radical scavengers and radical sinks. | The 2,2'-azinobis(3-ethylbenzothiazoline 6-sulfonic acid) radical cation (ABTS(*)(+)) decolorization assay has been used to determine the antioxidant activity of the polyphenol epicatechin(16) (4 --> 8) catechin (procyanidin, PC) alone or in complex with the model proteins bovine serum albumin (BSA) or gelatin. PC had ... | ['Antioxidants', 'Benzothiazoles', 'Biflavonoids', 'Catechin', 'Cations', 'Free Radical Scavengers', 'Free Radicals', 'Gelatin', 'Hydrogen-Ion Concentration', 'Hydrolyzable Tannins', 'Proanthocyanidins', 'Proteins', 'Serum Albumin, Bovine', 'Sulfonic Acids'] | 11,600,044 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D03.383.129.708.089', 'D03.633.100.185'], ['D03.383.663.283.266.450.190', 'D03.633.100.150.266.450.190'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['D01.248.497.300'], ['D27.505... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The alpha 2 chain of type 1 collagen does not map to mouse chromosome 16 but maps close to the Met proto-oncogene on mouse chromosome 6. | The gene locus for the alpha 2 chain of type 1 collagen (Cola-2) was previously assigned to chromosome 16. Here we demonstrate, utilising both somatic cell hybrid analysis and genetic linkage analysis, in an interspecific Mus domesticus x Mus spretus cross that Cola-2 fails to cosegregate with mouse chromosome 16, but ... | ['Animals', 'Chromosome Mapping', 'Collagen', 'Cricetinae', 'Cricetulus', 'Crosses, Genetic', 'Female', 'Hybrid Cells', 'Male', 'Mice', 'Nucleic Acid Hybridization', 'Proto-Oncogenes'] | 2,776,477 | [['B01.050'], ['E05.393.183'], ['D05.750.078.280', 'D12.776.860.300.250'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['E05.393.281'], ['A11.251.600'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.393.661', 'G02.111.611'], ['G05.360.340.024.340.375.500.791']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rectal cancer: mucinous carcinoma on magnetic resonance imaging indicates poor response to neoadjuvant chemoradiation. | PURPOSE: To assess response of locally advanced rectal carcinoma to chemoradiation with regard to mucinous status and local tumor invasion found at pretherapeutic magnetic resonance imaging (MRI).METHODS AND MATERIALS: A total of 88 patients were included in this prospective study of patients with advanced mrT3 and mrT... | ['Adenocarcinoma, Mucinous', 'Adult', 'Aged', 'Aged, 80 and over', 'Antimetabolites, Antineoplastic', 'Carcinoma', 'Chemoradiotherapy', 'Dose Fractionation, Radiation', 'Drug Administration Schedule', 'Female', 'Fluorouracil', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neoadjuvant Therapy', 'Neopla... | 21,236,593 | [['C04.557.470.200.025.075', 'C04.557.470.590.075'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['C04.557.470.200'], ['E02.186.079', 'E02.319.164', 'E02.815.160'], ['E02.815.639.200'], ['E02.319.283'], ['D03.383.742.698.875.404']... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Low population serum microneutralization antibody titer against the predominating influenza A(H3N2) N121K virus during the severe influenza summer peak of Hong Kong in 2017. | The 2017 Hong Kong influenza A(H3N2) summer season was unexpectedly severe. However, antigenic characterization of the 2017 circulating A(H3N2) viruses using ferret antisera did not show significant antigenic drift. We analyzed the hemagglutinin amino acid sequences of A(H3N2) virus circulating in Hong Kong in 2017, an... | ['Adolescent', 'Adult', 'Aged', 'Antibodies, Neutralizing', 'Antibodies, Viral', 'Female', 'Hong Kong', 'Humans', 'Influenza A Virus, H3N2 Subtype', 'Influenza Vaccines', 'Influenza, Human', 'Male', 'Middle Aged', 'Phylogeny', 'Seasons', 'Vaccination', 'Young Adult'] | 29,511,175 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.244', 'D12.776.124.790.651.114.244', 'D12.776.377.715.548.114.244'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['Z01.252.474.164.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Effect of Gum Chewing on the Volume and pH of Gastric Contents: A Prospective Randomized Study. | BACKGROUND: Insufficient fasting prior to endoscopic procedures performed under sedation may result in potential aspiration of gastric contents. Fasting as per ASA guidelines is recommended prior to these procedures. However, the effect of chewing gum on fasting status has been a subject of debate and often leads to pr... | ['Adult', 'Aged', 'Chewing Gum', 'Conscious Sedation', 'Endoscopy, Gastrointestinal', 'Fasting', 'Female', 'Gastrointestinal Contents', 'Humans', 'Hydrogen-Ion Concentration', 'Male', 'Middle Aged', 'Prospective Studies'] | 25,362,513 | [['M01.060.116'], ['M01.060.116.100'], ['D05.750.078.739.249', 'D09.698.700.249', 'D20.215.721.249.249', 'G07.203.300.140.200', 'J02.500.140.200'], ['E03.250'], ['E01.370.372.250.250', 'E01.370.388.250.250.250', 'E04.210.240.250', 'E04.502.250.250.250'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
FOXE1 polymorphisms are associated with familial and sporadic nonmedullary thyroid cancer susceptibility. | OBJECTIVE: FOXE1 is a transcription factor required for thyroid differentiation and function. FOXE1 locus polymorphisms (chromosome 9q22.33) were recently associated with increased sporadic thyroid cancer risk. In this study, we aimed to investigate the association of FOXE1 variants with nonmedullary thyroid cancer (NM... | ['Adenocarcinoma, Follicular', 'Aged', 'Aged, 80 and over', 'Forkhead Transcription Factors', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Humans', 'Linkage Disequilibrium', 'Middle Aged', 'Polymorphism, Genetic', 'Portugal', 'Sequence Analysis, DNA', 'Thyroid Neoplasms'] | 22,882,326 | [['C04.557.470.200.025.060'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.348.500'], ['M01.060.116.630'], ['G05.365.795'], ['Z01.542.727'], ['E05.393.760.700'], [... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Comparison of in vitro antibacterial activities of gentamicin and verdamicin. | The in vitro activities of verdamicin and gentamicin were studied in parallel against 1,049 bacterial isolates. Verdamicin demonstrated activity similar to that of gentamicin against members of the family Enterobacteriaceae and against Pseudomonas aeruginosa at 2 and 8 mug/ml, respectively. Proteus rettgeri and Provide... | ['Anti-Bacterial Agents', 'Gentamicins', 'Gram-Negative Bacteria'] | 4,157,358 | [['D27.505.954.122.085'], ['D09.408.051.374'], ['B03.440']] | ['Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enhanced specific antibody response to bovine serum albumin in pigeons due to L-carnitine supplementation. | 1. Thirty adult female pigeons (Columba livia domestica) were randomly divided into 3 equal groups; the 1st and 2nd groups were immunised with bovine serum albumin (BSA) at 0 and 20 d, the 2nd group also received 1 g L-carnitine per litre of drinking water from -5 to 25 d post-immunisation (dpi) and the 3rd group, a co... | ['Animals', 'Body Weight', 'Carnitine', 'Columbidae', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Immunoglobulin G', 'Immunoglobulin M', 'Linear Models', 'Random Allocation', 'Serum Albumin, Bovine'] | 11,128,385 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D02.092.877.883.099'], ['B01.050.150.900.248.165.150'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D12.776.124.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cardiac resynchronization therapy and the relationship of percent biventricular pacing to symptoms and survival. | BACKGROUND: With the advent of cardiac resynchronization therapy, it was unclear what percentage of biventricular pacing would be required to obtain maximal symptomatic and mortality benefit from the therapy. The optimal percentage of biventricular pacing and the association between the amount of continuous pacing and ... | ['Aged', 'Bundle-Branch Block', 'Cardiac Pacing, Artificial', 'Cohort Studies', 'Female', 'Heart Failure', 'Humans', 'Male', 'Massachusetts', 'Monitoring, Ambulatory', 'Product Surveillance, Postmarketing', 'Registries', 'Retrospective Studies', 'Survival Analysis', 'Treatment Outcome', 'United States'] | 21,699,828 | [['M01.060.116.100'], ['C14.280.067.558.323', 'C14.280.123.500.323', 'C23.550.073.425.100'], ['E02.331.200'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.550.510'], ['E01.370.520.500'], ['E05.337.800']... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cancer mortality among males in relation to exposures assessed through a job-exposure matrix. | To identify potential associations between workplace exposures and cancer mortality risks, job titles collected from 1965 to 1971 for 58,678 men (a subset of a large representative sample of the Canadian workforce) were transformed into probable chemical exposures using a job-exposure matrix developed in Montreal. Mort... | ['Adult', 'Aged', 'Canada', 'Databases, Factual', 'Death Certificates', 'Environmental Monitoring', 'Epidemiological Monitoring', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Neoplasms', 'Occupational Exposure', 'Occupations', 'Population Surveillance', 'Prevalence', 'Regression Analysis', 'Risk', 'Risk Facto... | 10,926,723 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.107.567.176'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E05.318.308.940.350', 'L01.399.250.900.350', 'N04.452.859.264', 'N05.715.360.300.715.315', 'N06.850.520.308.940.350'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E05.318.375', 'N06.850.520.460'], ['E05.3... | ['Named Groups [M]', 'Geographicals [Z]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
[Use of cabergoline for prevention of ovarian hyperstimulation syndrome in assisted reproductive technologies]. | Presentation of seven cases of patients at risk for moderate or severe OHSS, treated with Cabergoline. | ['Cabergoline', 'Dopamine Agonists', 'Ergolines', 'Female', 'Humans', 'Ovarian Hyperstimulation Syndrome', 'Ovary', 'Ovulation Induction', 'Pregnancy'] | 25,558,669 | [['D03.132.327.287.131', 'D03.633.400.439.197'], ['D27.505.519.625.150.151', 'D27.505.696.577.150.151'], ['D03.132.327.287', 'D03.633.400.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.056.630.642', 'C19.391.630.642'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['E02.875.800.9... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Correlation between the phenotypic domains of the UPOINT system and sexual dysfunction in men with chronic prostatitis/chronic pelvic pain syndrome]. | Objective: To investigate the correlation of the six phenotypic domains of the UPOINT (urinary, psychosocial, organ-specific, infection, neurologic/systemic, and tenderness) system with premature ejaculation (PE) and ED in male patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).METHODS: We collect... | ['Adult', 'Chronic Disease', 'Chronic Pain', 'Erectile Dysfunction', 'Humans', 'Male', 'Pelvic Pain', 'Phenotype', 'Premature Ejaculation', 'Prostatitis'] | 32,223,082 | [['M01.060.116'], ['C23.550.291.500'], ['C23.888.592.612.274'], ['C12.294.644.486', 'F03.835.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.944'], ['G05.695'], ['C12.294.644.743', 'F03.835.700'], ['C12.294.565.750']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fooled by local robustness: an applied ecology perspective. | In this short discussion, we point out that it is apparently as easy to be fooled by robustness as it is to be fooled by randomness. Our objective is to bring to the attention of applied ecologists that radius-of-stability robustness models are models of local robustness. As such, these models are utterly unsuitable fo... | ['Conservation of Natural Resources', 'Ecosystem', 'Models, Biological', 'Population Dynamics'] | 22,908,702 | [['J01.256', 'N06.230.080'], ['G16.500.275.157', 'N06.230.124'], ['E05.599.395'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700']] | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
Ab initio folding of albumin binding domain from all-atom molecular dynamics simulation. | Ab initio folding with all-atom model remains to be a difficult task even for small proteins. In this report, we conducted an accumulated 24 mus simulations on the wild type and two mutants of albumin binding domain (ABD) using the AMBER FF03 all-atom force field and a generalized-Born solvation model. Folding events h... | ['Albumins', 'Binding Sites', 'Models, Molecular', 'Protein Binding', 'Protein Conformation', 'Protein Folding', 'Protein Structure, Tertiary'] | 17,458,992 | [['D12.776.034'], ['G02.111.570.120'], ['E05.599.595'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709'], ['G01.154.651', 'G02.111.688'], ['G02.111.570.820.709.610']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Issues surrounding psychological testing of minority patients. | Psychological testing of minority patients is a frequently debated issue, not only in the scientific literature, but in the mass media, the courts, and legislative bodies. A historical overview of the controversy illustrates past abuses in such testing, but a closer look at methodological issues concerning cognitive-in... | ['Cultural Characteristics', 'Humans', 'Intelligence Tests', 'Language', 'MMPI', 'Minority Groups', 'Professional-Patient Relations', 'Psychological Tests', 'Social Environment'] | 3,557,344 | [['I01.076.201.450.324', 'I01.880.853.100.329'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.141.493'], ['F01.145.209.399', 'L01.559'], ['F04.711.647.513.607'], ['I01.880.853.300'], ['F01.829.401.650', 'N05.300.660'], ['F04.711'], ['I01.880.853.500']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
A factor analytic investigation of home-bound elderly individuals' concerns about death and dying, and their coping responses. | One hundred and seventy-eight home-bound elderly men and women participated in an investigation of death and dying concerns and coping responses used to deal with these anxieties. A semi-structured interview procedure was used to obtain responses from the subjects. The data subsequently were subjected to two factor ana... | ['Adaptation, Psychological', 'Aged', 'Aged, 80 and over', 'Anxiety', 'Attitude to Death', 'Disabled Persons', 'Fear', 'Female', 'Humans', 'Interview, Psychological', 'Male', 'Psychometrics'] | 2,149,563 | [['F01.058'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.470.132'], ['F01.100.125', 'N05.300.125'], ['M01.150'], ['F01.470.361'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.669.599'], ['F04.711.780']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Uncoupling of RNA and DNA synthesis after plasma stimulation of G0-arrested BALB/C-3T3 cells. | The addition of whole serum to G0-arrested, confluent Balb/c-3T3 cells induces them to progress through G1 and synthesize DNA after a 12-h lag period. Prior to the onset of DNA synthesis, RNA is synthesized and RNA content increases. Serum has been fractionated into two sets of growth factors: a platelet-derived growth... | ['Animals', 'Blood', 'Blood Platelets', 'Cell Division', 'Cell Line', 'Culture Media', 'DNA', 'Mice', 'Mice, Inbred BALB C', 'RNA'] | 427,156 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Abiotic and biological mechanisms of nitric oxide removal from waste air in biotrickling filters. | Nitric oxide (NO) may participate in the ozone layer depletion and forming of nitric acid. Abiotic and biological mechanisms of NO removal from waste gases were studied in a biotrickling filter. The abiotic NO removal rate in the biotrickling filter was estimated by a review of the literature. The abiotic and biologica... | ['Air Pollutants', 'Air Pollution', 'Biodegradation, Environmental', 'Biofilms', 'Filtration', 'Nitric Oxide', 'Oxidation-Reduction'] | 16,499,144 | [['D27.888.284.101'], ['N06.850.460.100'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['A20.593', 'G06.120'], ['E05.196.454', 'G01.280', 'G02.263'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['G02.700', 'G03.295.531']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
["And thus there was another pointless thing in the country [...]". The failed homoeopathic training of missionaries at the Basle Mission]. | This article deals with the unsuccessful attempts to allow missionaries of the Basle Mission to undergo homoeopathic training. Before the Mission undertook systematic medical missionary work in society in the 1880s, there were various requests and suggestions to train the missionaries in homoeopathy. Here, these attemp... | ['Christianity', 'Correspondence as Topic', 'Education, Medical', 'History, 18th Century', 'History, 19th Century', 'Homeopathy', 'Humans', 'Missionaries', 'Religion and Medicine', 'Religious Missions', 'Switzerland'] | 21,796,904 | [['K01.844.188'], ['L01.559.423.906.377'], ['I02.358.399'], ['K01.400.504.875'], ['K01.400.504.937'], ['E02.190.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.427'], ['K01.844.619'], ['K01.844.777', 'N03.540.297.500'], ['Z01.542.883']] | ['Humanities [K]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Antisera from mice and rats incubated with syngeneic Rous sarcoma cells. | CDF1, (BALB/c X DBA/2)F1, mice were repeatedly inoculated with transplantable mouse Rous sarcoma (SR-CDF1) cells which were half-killed by 60Co-irradiation beforehand to attain prolonged immunization. The sera obtained from these mice contained antibodies against the src and gag gene products of Rous sarcoma virus (RSV... | ['Alpharetrovirus', 'Animals', 'Antibodies, Viral', 'Cell Transformation, Viral', 'Immune Sera', 'Immunization', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred DBA', 'Rats', 'Rats, Inbred F344', 'Sarcoma, Avian'] | 6,259,386 | [['B04.613.807.070', 'B04.820.650.070'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['C04.697.098.500.160', 'C23.550.727.098.500.160', 'G06.920.143'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Early detection of subclinical edema in chronic kidney disease patients by bioelectrical impedance analysis. | BACKGROUND: Abnormalities in body water distribution are common in chronic kidney disease (CKD) patients. Volume expansion, even in the absence of overt edema, contributes to high blood pressure, and progressive volume expansion eventually leads to clinical edema and fluid overload. Total body water (TBW) can be accura... | ['Adult', 'Aged', 'Early Diagnosis', 'Edema', 'Electric Impedance', 'Female', 'Humans', 'Male', 'Middle Aged', 'Renal Insufficiency, Chronic', 'Young Adult'] | 25,509,689 | [['M01.060.116'], ['M01.060.116.100'], ['E01.390'], ['C23.888.277'], ['G01.358.500.249.277.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C12.777.419.780.750', 'C13.351.968.419.780.750'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The TRIP from ULF to ARF. | ARF is a key activator of p53, and together they form a critical duo for protection against cancer. Previous evidence had recognized the regulatory potential of ubiquitin-mediated degradation of ARF. The recent identification of TRIP12/ULF as a ubiquitin ligase of ARF adds an important missing piece to the ARF/p53 path... | ['ADP-Ribosylation Factor 1', 'ADP-Ribosylation Factors', 'Animals', 'Apoptosis', 'Cell Cycle', 'Cyclin-Dependent Kinase Inhibitor p16', 'Exons', 'Genes, p16', 'Humans', 'Mice', 'Neoplasms', 'Oncogenes', 'Tumor Suppressor Protein p53', 'Ubiquitin-Protein Ligases', 'Ubiquitins'] | 20,385,357 | [['D08.811.277.040.330.300.400.100.100', 'D12.644.360.525.100.100', 'D12.776.157.325.515.100.100', 'D12.776.476.525.100.100', 'D12.776.543.990.300.150'], ['D08.811.277.040.330.300.400.100', 'D12.644.360.525.100', 'D12.776.157.325.515.100', 'D12.776.476.525.100'], ['B01.050'], ['G04.146.954.035'], ['G04.144'], ['D12.644... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessment of work-related exposure to polycyclic aromatic hydrocarbons in Italy. | BACKGROUND: Polycyclic aromatic hydrocarbons (PAHs) are generally present in the workplace environment as complex mixtures and often difficult to identify a priori.OBJECTIVES: The aim of this study is to evaluate the level and coverage of occupational exposure to PAHs in Italy.METHODS: Data were collected from exposure... | ['Air Pollutants, Occupational', 'Databases, Factual', 'Environmental Monitoring', 'Female', 'Humans', 'Italy', 'Male', 'Models, Statistical', 'Occupational Exposure', 'Polycyclic Aromatic Hydrocarbons', 'Principal Component Analysis', 'Registries'] | 23,450,729 | [['D27.888.284.101.268'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['N06.850.460.350.600'], ['D02.455.426.559.847', '... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
[A case of intracranial hemorrhage following superior sagittal sinus thrombosis associated with nephrotic syndrome]. | A case of intracranial hemorrhage due to superior sagittal sinus thrombosis occurring in a boy with nephrotic syndrome is described. A twelve-year-old boy with nephrotic syndrome presented sudden onset of generalized convulsions. CT scan revealed a subcortical hematoma in the left frontal lobe. A left carotid angiograp... | ['Cerebral Hemorrhage', 'Child', 'Humans', 'Male', 'Nephrotic Syndrome', 'Sinus Thrombosis, Intracranial', 'Tomography, X-Ray Computed'] | 9,430,145 | [['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.630.643', 'C13.351.968.419.630.643'], ['C10.228.140.300.525.425.500', 'C14.907.253.566.350.500', 'C14.907.355.590.213.350.500'], ['E01.370.350.350.810', 'E01.370.35... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The role of delayed hypersensitivity in the development of an experimental dysentery infection and vaccinal process]. | The results of experiments, indicating the development of cell-mediated delayed hypersensitivity (DH) skin reaction, its dependence on the virulence of Shigella flexneri 2a, the dose and the character of the antigen used for testing the reaction, are presented. One of the immunologically active components of S. flexner... | ['Animals', 'Antigens, Bacterial', 'Dose-Response Relationship, Immunologic', 'Dysentery, Bacillary', 'Hypersensitivity, Delayed', 'Immunization', 'Immunization, Passive', 'Male', 'Mice', 'Mice, Inbred CBA', 'Mutation', 'Shigella flexneri', 'Skin Tests', 'Spleen', 'Time Factors', 'Virulence'] | 2,698,032 | [['B01.050'], ['D23.050.161'], ['G12.300'], ['C01.150.252.400.310.229', 'C06.405.205.331.479', 'C06.405.469.300.479'], ['C20.543.418'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['E02.095.465.425.400.330', 'E05.478.550.520'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Antinociceptive efficacy and respiratory effects of dexmedetomidine in ball pythons (Python regius). | OBJECTIVE To determine antinociceptive efficacy, behavioral patterns, and respiratory effects associated with dexmedetomidine administration in ball pythons (Python regius). ANIMALS 12 ball pythons. PROCEDURES Antinociception was assessed by applying an infrared heat stimulus to the cranioventral surface of snakes duri... | ['Analgesics, Non-Narcotic', 'Animals', 'Behavior, Animal', 'Boidae', 'Dexmedetomidine', 'Drug Administration Schedule', 'Female', 'Male', 'Respiration', 'Temperature', 'Time Factors'] | 29,943,640 | [['D27.505.696.663.850.014.040', 'D27.505.954.427.040.100'], ['B01.050'], ['F01.145.113'], ['B01.050.150.900.833.672.125.500'], ['D03.383.129.308.245'], ['E02.319.283'], ['G09.772.705'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Synthesis of prostaglandin E2, thromboxane B2 and prostaglandin catabolism in gastritis and gastric ulcer. | Because endogenous prostaglandins may protect the gastric mucosa a study was conducted to determine factors influencing the synthesis of immunoreactive prostaglandin (iPG) E2 and thromboxane (iTx) B2 as measured by radioimmunoassay and prostaglandin catabolism measured radiometrically, in human gastric mucosa. Gastric ... | ['Dinoprostone', 'Female', 'Gastric Mucosa', 'Gastritis', 'Humans', 'Indomethacin', 'Male', 'Prostaglandin Antagonists', 'Prostaglandins', 'Prostaglandins E', 'Radioimmunoassay', 'Stomach Ulcer', 'Thromboxane B2'] | 3,468,053 | [['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['A03.556.875.875.440', 'A10.615.550.291'], ['C06.405.205.697', 'C06.405.748.398'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.420'], ['D06.347.710', 'D27.505.696.399.450.710'], ['D10.251.355.255.550', 'D23.469.050.175.725'], ['D10... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acute hepatitis E by a new isolate acquired in the United States. | OBJECTIVE: To report the first case of acute hepatitis E by a novel isolate acquired in the United States and confirmed by nucleotide sequencing.MATERIAL AND METHODS: We describe the clinical manifestations and the results of associated laboratory studies in a man who was found to have acute hepatitis E infection.RESUL... | ['Acute Disease', 'Diagnosis, Differential', 'Hepatitis Antibodies', 'Hepatitis E', 'Hepatitis E virus', 'Humans', 'Immunoglobulin G', 'Male', 'Middle Aged', 'Polymerase Chain Reaction', 'RNA, Viral', 'RNA-Directed DNA Polymerase'] | 9,413,292 | [['C23.550.291.125'], ['E01.171'], ['D12.776.124.486.485.114.254.450', 'D12.776.124.790.651.114.254.450', 'D12.776.377.715.548.114.254.450'], ['C01.925.440.470', 'C01.925.782.455', 'C06.552.380.705.470'], ['B04.450.412', 'B04.820.578.407.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Scandinavian guidelines for initial management of minimal, mild, and moderate head injuries. The Scandinavian Neurotrauma Committee. | BACKGROUND: The Scandinavian Neurotrauma Committee was initiated by the Scandinavian Neurosurgical Society to develop evidence-based guidelines for improved care of neurotrauma patients.METHODS: A MEDLINE search identified 475 papers dealing with the management of minimal, mild, and moderate head injuries. Forty-two st... | ['Craniocerebral Trauma', 'Humans', 'Scandinavian and Nordic Countries', 'Trauma Severity Indices'] | 10,780,615 | [['C10.900.300', 'C26.915.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.816'], ['E05.318.308.940.968.875', 'E05.944', 'N04.452.859.564.800', 'N05.715.360.300.715.500.800', 'N06.850.520.308.940.968.875']] | ['Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Development of novel mucoadhesive pellets of metformin hydrochloride. | Mucoadhesive polymer-coated pellets containing metformin hydrochloride were prepared by the powder-layering technique using a centrifugal fluidizing (CF)-granulator. Four high-viscosity polymers were applied to make the pellets: 1) hydroxymethylcellulose (HPMC), 2) sodium alginate (Na-Alg), 3) HPMC/Carbopol, and 4) sod... | ['Acrylic Resins', 'Adhesiveness', 'Alginates', 'Animals', 'Capsules', 'Carboxymethylcellulose Sodium', 'Chemistry, Pharmaceutical', 'Delayed-Action Preparations', 'Drug Carriers', 'Gastric Mucosa', 'Glucuronic Acid', 'Hardness', 'Hexuronic Acids', 'Hypoglycemic Agents', 'Hypromellose Derivatives', 'Kinetics', 'Metform... | 19,387,583 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['G02.860.139'], ['D09.698.068'], ['B01.050'], ['D26.255.150'], ['D09.698.365.180.663.329'], ['H01.158.703.007', 'H01.181.466'], ['D26.255.210', 'E02.319.300.253'], ['D26.255.260', 'E02.319.300.380'], ['A03.556.875.875.440', 'A10.615.550.29... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Pooled analysis of association between a genetic variant in the 3'-untranslated region of Toll-like receptor 4 and cancer risk. | Many epidemiological studies have shown the association between certain genetic variations in the Toll-like receptor 4 (TLR4) gene (for example, rs4986790 and rs4986791) and cancer risk. However, the results from investigations into the association between rs11536889, a genetic variant in the 3'-untranslated region of ... | ["3' Untranslated Regions", 'Alleles', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Male', 'Polymorphism, Single Nucleotide', 'Prostatic Neoplasms', 'Toll-Like Receptor 4'] | 26,782,430 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['G05.360.340.024.340.030'], ['E05.393.385'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.795.598'], ['C04.588.945.440.770', 'C12... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evidence of increasing public participation in advance care planning: a comparison of polls in Alberta between 2007 and 2013. | BACKGROUND: Advance care planning (ACP) encompasses both verbal and written communications expressing preferences for future health and personal care and helps prepare people for healthcare decision-making in times of medical crisis. Healthcare systems are increasingly promoting ACP as a way to inform medical decision-... | ['Adolescent', 'Adult', 'Advance Care Planning', 'Aged', 'Aged, 80 and over', 'Alberta', 'Community Participation', 'Female', 'Forecasting', 'Humans', 'Male', 'Middle Aged', 'Young Adult'] | 26,817,793 | [['M01.060.057'], ['M01.060.116'], ['N04.590.233.624.124'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.567.176.064'], ['N02.421.143.212', 'N03.540.245.360'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.060.116.815']] | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Cost-effectiveness analysis of ribotype-guided fecal microbiota transplantation in Chinese patients with severe Clostridium difficile infection. | BACKGROUND: Clostridium difficile infection (CDI) caused by ribotype 002 strain is associated with poor outcomes in Chinese patients. Fecal microbiota transplantation (FMT) is an effective but costly treatment for CDI. We aimed to examine potential cost-effectiveness of ribotype-guided FMT in Chinese patients with seve... | ['Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Asian Continental Ancestry Group', 'China', 'Clostridioides difficile', 'Clostridium Infections', 'Cost-Benefit Analysis', 'Decision Support Techniques', 'Enterocolitis, Pseudomembranous', 'Fecal Microbiota Transplantation', 'Female', 'Gene Frequency', 'Humans', '... | 30,048,534 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['M01.686.508.200'], ['Z01.252.474.164'], ['B03.353.625.657.500'], ['C01.150.252.410.222'], ['N03.219.151.125'], ['E05.245', 'L01.313.500.750.190'], ['C01.150.252.410.222.310', 'C06.405.205.596.800', 'C06.405.469.363.800'], ['E02.095.231'], ['G05.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Klebocin typing of Klebsiella species isolated from nosocomial infection in intensive care unit. | Klebocin typing and antibiotic resistance have been studied for 518 strains of Klebsiella pneumoniae, [106 from intensive care unit (ICU) sites, 182 from ICU staff flora, 192 from patient flora and 38 from clinical specimens]. The overall typability was 71.62%. The most common mnemonic types among various sources were ... | ['Bacteriocins', 'Cross Infection', 'Humans', 'Intensive Care Units', 'Klebsiella Infections', 'Klebsiella pneumoniae', 'Microbial Sensitivity Tests'] | 10,740,735 | [['D12.776.097.151', 'D12.776.543.695.110'], ['C01.248', 'C23.550.291.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['C01.150.252.400.310.503'], ['B03.440.450.425.425.600', 'B03.660.250.150.400.590'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of silorane and methacrylate-based composite resins on the curing light transmission. | The aim of this study was to investigate the influence of different composite resins - Filtek P90 (silorane-based composite) and Heliomolar (methacrylate-based composite) - on light transmission and decrease in Knoop hardness between the bottom and top of cured specimens. The irradiance of a light-curing unit (LCU) was... | ['Acrylic Resins', 'Composite Resins', 'Dental Stress Analysis', 'Hardness', 'Light-Curing of Dental Adhesives', 'Materials Testing', 'Methacrylates', 'Optical Phenomena', 'Polymerization', 'Polyurethanes', 'Silorane Resins', 'Siloxanes'] | 21,271,045 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['E06.308'], ['G01.374.647'], ['E06.095.585'], ['E05.570'], ['D02.241.081.069.600'], ['G01.590'], ['G02.750'], ['D0... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Selective modulation of excitatory and inhibitory microcircuits by dopamine. | Dopamine plays an important role in the working memory functions of the prefrontal cortex, functions that are impacted in age-related memory decline, drug abuse, and a wide variety of disorders, including schizophrenia and Parkinson's disease. We have previously reported that dopamine depresses excitatory transmission ... | ['Animals', 'Axons', 'Dopamine', 'Electrophysiology', 'Ferrets', 'Neural Inhibition', 'Neurons', 'Prefrontal Cortex', 'Pyramidal Cells', 'Synapses', 'Synaptic Transmission', 'Time Factors'] | 12,591,942 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['H01.158.344.528', 'H01.158.782.236'], ['B01.050.150.900.649.313.750.250.575.350'], ['G07.265.755', 'G11.561.616'], ['A08.675', 'A11.671'], ['A08.18... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Rational design, synthesis and anti-proliferative evaluation of novel 1,4-benzoxazine-[1,2,3]triazole hybrids. | A series of novel 1,2,3-triazole-1,4-benzoxazine hybrids 5a-n were efficiently synthesized employing click chemistry approach and evaluated for anti-proliferative activity against four cancer cell lines such as HeLa (cervical), MIAPACA (pancreatic), MDA-MB-231 (breast) and IMR32 (neuroblastoma). Compounds 5n and 5g exh... | ['Antineoplastic Agents', 'Benzoxazines', 'Cell Line, Tumor', 'Cell Proliferation', 'Dose-Response Relationship, Drug', 'Drug Design', 'Drug Screening Assays, Antitumor', 'HeLa Cells', 'Humans', 'Molecular Structure', 'Structure-Activity Relationship', 'Triazoles'] | 25,462,234 | [['D27.505.954.248'], ['D03.383.533.249', 'D03.633.100.209'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Biofilm promoted current generation of Pseudomonas aeruginosa microbial fuel cell via improving the interfacial redox reaction of phenazines. | Bacteria biofilm plays a key role in current generation of microbial fuel cells (MFCs), especially for the start-up stage. However, the detailed mechanism of the biofilm promoting the power generation is not very clear so far, especially for those exoelectrogens who rely on the self-excreted electron mediators for extr... | ['Bioelectric Energy Sources', 'Biofilms', 'Electric Conductivity', 'Electrochemistry', 'Electrodes', 'Electron Transport', 'Phenazines', 'Pseudomonas aeruginosa'] | 28,575,838 | [['E07.305.124.150'], ['A20.593', 'G06.120'], ['G01.358.500.249.277'], ['H01.181.529.307'], ['E07.305.250'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['D03.633.300.704'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The reinnervation of healing extraction sockets in the ferret. | The objective of this study was to describe the pattern of healing of pulpal and periodontal nerve fibers following tooth extraction. The mandibular canine teeth were, under general anesthesia, removed from one side of nine young ferrets. One week (two animals), one month (four animals), and three months (three animals... | ['Alveolar Process', 'Animals', 'Computer Simulation', 'Ferrets', 'Nerve Regeneration', 'Silver Staining', 'Tooth Extraction', 'Wound Healing'] | 8,360,365 | [['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['B01.050'], ['L01.224.160'], ['B01.050.150.900.649.313.750.250.575.350'], ['G11.561.585', 'G16.762.611'], ['E01.370.225.500.620.670.780', 'E01.370.225.750.600.670.780', 'E05.200.500.620.670.780', 'E05.200.750.600.670.780'], ['E04.545.700', 'E06.64... | ['Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Methodology for the systematic reviews of occupational therapy for children and adolescents with difficulty processing and integrating sensory information. | Systematic reviews of literature relevant to children and adolescents with difficulty processing and integrating sensory information are important to the practice of occupational therapy in this area. This article explains the five questions that were developed and served as the focus for these reviews: neuronal plasti... | ['Adolescent', 'Child', 'Evidence-Based Practice', 'Humans', 'Occupational Therapy', 'Peer Review, Research', 'Perceptual Disorders', 'Sensation Disorders'] | 20,608,269 | [['M01.060.057'], ['M01.060.406'], ['H02.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.169.063.500.489', 'E02.831.489', 'H02.010.500'], ['F01.829.316.549.700', 'H01.770.644.487', 'I01.880.604.640.700', 'L01.143.865.750', 'L01.737.640', 'N03.706.700.700'], ['C10.597.606.762', 'C23.888.592.604.764', '... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Neuronal nitric oxide synthase interacts with Sp1 through the PDZ domain inhibiting Sp1-mediated copper-zinc superoxide dismutase expression. | In this report we demonstrate that neuronal nitric oxide synthase (nNOS) is able to interact with Sp1 both in vivo and in vitro. In particular, we show that such interaction is mediated by the N-terminal PDZ domain of full length nNOS (fl-nNOS). In fact nNOS mutant lacking the PDZ domain (ÄnNOS) displays an impaired ab... | ['Animals', 'Copper', 'Gene Expression Regulation, Enzymologic', 'Humans', 'Immunoglobulins', 'Immunoprecipitation', 'Mice', 'Neurons', 'Nitric Oxide', 'Nitric Oxide Synthase Type I', 'PDZ Domains', 'Protein Binding', 'RNA, Messenger', 'Rats', 'Superoxide Dismutase', 'Tumor Cells, Cultured', 'Zinc'] | 21,056,687 | [['B01.050'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['G05.308.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485', 'D12.776.124.790.651', 'D12.776.377.715.548'], ['E05.196.150.639', 'E05.478.605'], ['B01.050.150.900.649.313.992.635.505.500'], ['A08.675', 'A11.671'], ['D01... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical significance of co-expression of aberrant antigens in acute leukemia: a retrospective cohort study in Makah Al Mukaramah, Saudi Arabia. | BACKGROUND: Aberrant phenotypes in acute leukemia have variable frequency and their prognostic and predictive relevance is controversial, despite several reports of clinical significance.AIMS: To determine the prevalence of aberrant antigen expression in acute leukemia, assess clinical relevance and demonstrate immunop... | ['Adolescent', 'Adult', 'Aged', 'Antigens, CD', 'Antigens, Ly', 'Antigens, Neoplasm', 'Disease-Free Survival', 'Female', 'Humans', 'Immunophenotyping', 'Kaplan-Meier Estimate', 'Karyotype', 'Leukemia, Myeloid, Acute', 'Male', 'Middle Aged', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Retrospective Studies', 'Sau... | 24,528,030 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.920', 'D23.101.100.920'], ['D23.050.285'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Nondestructive evaluation of cell numbers in bone marrow stromal cell/beta-tricalcium phosphate composites using ultrasound. | Composites of bone marrow stromal cells (BMSCs)/beta-tricalcium phosphate (beta-TCP) have been increasingly used as bone substitutes and studied as a bone graft model for bone tissue engineering. The number of seeded cells in the composites is a crucial factor for achieving successful bone tissue regeneration. In this ... | ['Animals', 'Bone Marrow Cells', 'Calcium Phosphates', 'Rats', 'Rats, Sprague-Dawley', 'Stromal Cells', 'Trypsin', 'Ultrasonics'] | 19,580,422 | [['B01.050'], ['A11.148', 'A15.378.316'], ['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['A11.329.830'], ['D08.811.277.656.300.760.895', 'D08.811.277.656.959.350.895'], ['H01.671.031.849']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Executive functioning of Portuguese preschoolers in the Shape School test: A cross cultural study. | The Shape School is a neuropsychological test of executive functions (EF) for preschool-aged children. The purposes of this study were: (a) to adapt the use of the Shape School for European Portuguese preschool children and (b) to examine the cultural sensitivity of this test comparing the performance of Portuguese sam... | ['Behavior', 'Child', 'Child Development', 'Child, Preschool', 'Cross-Cultural Comparison', 'Executive Function', 'Female', 'Humans', 'Male', 'Neuropsychological Tests', 'Portugal', 'Task Performance and Analysis'] | 28,631,966 | [['F01.145'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513'], ['Z01.542.727'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Meningioma transcript profiles reveal deregulated Notch signaling pathway. | Meningiomas constitute the second most common central nervous system tumor, and yet relatively little is known about the molecular events that are important for the pathogenesis and malignant progression of these tumors. We have used serial analysis of gene expression to compare the transcriptomes of nonneoplastic meni... | ['Basic Helix-Loop-Helix Transcription Factors', 'Calcium-Binding Proteins', 'Cell Line, Tumor', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Homeodomain Proteins', 'Humans', 'Intercellular Signaling Peptides and Proteins', 'Jagged-1 Protein', 'Ligands', 'Membrane Proteins', 'Meningeal Neopla... | 15,958,550 | [['D12.776.260.103', 'D12.776.930.125'], ['D12.776.157.125'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.393.332'], ['G05.308.370'], ['D12.776.260.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276', 'D12.776.467', 'D23.529'], ['D12.644.276.930.500', 'D12.776.157.125.797.500', 'D12.776.543.800.500... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake. | High-affinity cellular copper uptake is mediated by the CTR (copper transporter) 1 family of proteins. The highly homologous hCTR (human CTR) 2 protein has been identified, but its function in copper uptake is currently unknown. To characterize the role of hCTR2 in copper homoeostasis, epitope-tagged hCTR2 was transien... | ['Amino Acid Sequence', 'Biological Transport', 'Cation Transport Proteins', 'Cell Membrane', 'Cells, Cultured', 'Copper', 'Copper Transporter 1', 'Cytosol', 'Endosomes', 'HeLa Cells', 'Humans', 'Lysosomes', 'Molecular Sequence Data', 'SLC31 Proteins', 'Sequence Alignment', 'Transfection'] | 17,617,060 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G03.143'], ['D12.776.157.530.450.250', 'D12.776.543.585.450.250'], ['A11.284.149'], ['A11.251'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D12.776.157.530.450.250.578.875.500', 'D12.776.157.530.937.640.500', 'D12.776.543.585.450.250.578.875.500', 'D12.77... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Hemocytes of Rhynchophorus ferrugineus (Olivier) (Coleoptera: Curculionidae) and their response to Saccharomyces cerevisiae and Bacillus thuringiensis. | Originally from tropical Asia, the Red Palm Weevil (RPW Rhynchophorus ferrugineus (Olivier)) is the most dangerous and deadly pest of many palm trees, and there have been reports of its recent detection in France, Greece and Italy. At present, emphasis is on the development of integrated pest management based on biolog... | ['Animals', 'Bacillus thuringiensis', 'Blood Cell Count', 'Hemocytes', 'Hemolymph', 'Host-Pathogen Interactions', 'Larva', 'Pest Control, Biological', 'Phagocytosis', 'Saccharomyces cerevisiae', 'Weevils'] | 21,147,119 | [['B01.050'], ['B03.300.390.400.158.218.800', 'B03.353.500.100.218.800', 'B03.510.100.100.218.800', 'B03.510.415.400.158.218.800', 'B03.510.460.410.158.218.800'], ['E01.370.225.500.195.107', 'E01.370.225.625.107', 'E05.200.500.195.107', 'E05.200.625.107', 'E05.242.195.107', 'G04.140.107', 'G09.188.105'], ['A11.118.480'... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Reaction of tryptophanyl-tRNA synthetase from beef pancreas with periodate-oxidized ATP. | Tryptophanyl-tRNA synthetase from beef pancreas reacts with periodate-oxidized ATP according to biphasic kinetics. A rapid phase involves two groups of the protein, presumably lysine side-chains. The slow phase corresponds to the reaction of a larger number of groups. The time-course of the partial losses of the ATP-PP... | ['Adenosine Triphosphate', 'Amino Acyl-tRNA Synthetases', 'Animals', 'Cattle', 'Diphosphates', 'Kinetics', 'Pancreas', 'RNA, Transfer, Trp', 'Tryptophan-tRNA Ligase'] | 2,820,730 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D08.811.464.263.200'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D01.029.260.700.675.374.775.150', 'D01.248.497.158.730.650.200', 'D01.695.625.675.650.775.150'], ['G01.374.661', 'G02.111.490'], ['A03.734'], ['D13.444.735.757... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Emotional processing in survivors of the Jupiter cruise ship disaster. | Twenty-three survivors of the Jupiter cruise ship disaster completed the Impact of Events Scale, a measure of intrusion and avoidance, as well as measures of arousal and affect at two points in time: between 3 and 7 months (Time 1) and between 12 and 14 months (Time 2) following the event. The aim of the present study ... | ['Adaptation, Psychological', 'Adult', 'Aged', 'Anxiety', 'Defense Mechanisms', 'Depression', 'Disasters', 'Female', 'Greece', 'Humans', 'Male', 'Middle Aged', 'Personality Assessment', 'Personality Inventory', 'Ships', 'Stress Disorders, Post-Traumatic', 'Survival'] | 7,887,877 | [['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['F01.470.132'], ['F01.393'], ['F01.145.126.350'], ['N06.230.100'], ['Z01.542.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.513'], ['F04.711.647.513'], ['J01.937.817'], ['F03.950.750.500'], ['I03.784']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Total synthesis, structure revision, and absolute configuration of (-)-brevenal. | Total synthesis of structure 1 originally proposed for brevenal, a nontoxic polycyclic ether natural product isolated from the Florida red tide dinoflagellate, Karenia brevis, was accomplished. The key features of the synthesis involved (i) convergent assembly of the pentacyclic polyether skeleton based on our develope... | ['Magnetic Resonance Spectroscopy', 'Molecular Conformation', 'Sensitivity and Specificity', 'Stereoisomerism', 'Thiopental'] | 17,177,450 | [['E05.196.867.519'], ['G02.111.570.820'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872'], ['G02.607.445.682'], ['D03.383.742.698.253.800.810']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Failure of histiocytosis X cells to express i blood group antigen. | Expression of HLADR, I, i blood group antigen and T6 antigen were studied in Histiocytosis X cells and pulmonary alveolar macrophages using double labelling immunofluorescence technique or immuno-peroxidase procedure. Alveolar macrophages express simultaneously HLADR and i blood group antigen. Histiocytosis X cells, ch... | ['Blood Group Antigens', 'Bone Diseases', 'Fluorescent Antibody Technique', 'Granuloma', 'Histiocytosis, Langerhans-Cell', 'Humans', 'I Blood-Group System', 'Immune Sera', 'Immunoenzyme Techniques', 'Macrophages', 'Microscopy, Electron', 'Skull'] | 3,913,947 | [['D23.050.301.290', 'D23.050.705.230'], ['C05.116'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['C15.604.515.292', 'C23.550.382'], ['C08.381.483.375', 'C15.604.250.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D2... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Leptin has concentration and stage-dependent effects on embryonic development in vitro. | There is accumulating evidence that leptin may be directly involved in pre-implantation embryonic development, however, it is unclear whether there is a concentration and stage-dependent regulatory pattern. In this study, the addition of 10 ng/ml human recombinant leptin to the culture medium significantly increased th... | ['Animals', 'Blastocyst', 'Cleavage Stage, Ovum', 'Dose-Response Relationship, Drug', 'Electrophoresis', 'Embryo Culture Techniques', 'Embryonic Development', 'Female', 'Leptin', 'Mice', 'Mice, Inbred Strains', 'Pregnancy', 'Protein Isoforms', 'RNA, Messenger', 'Receptors, Cell Surface', 'Receptors, Leptin', 'Recombina... | 16,885,533 | [['B01.050'], ['A16.254.500'], ['A16.166'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.196.401', 'E05.301.300'], ['E05.481.500.468'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['D06.472.699.042.500', 'D12.644.276.024.500', 'D12.644.548.011.500', 'D12.776.467.024.500', 'D23.529.024.500'], ['B01.050.150.900.649.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rituximab combined with conventional therapy versus conventional therapy alone for the treatment of mucous membrane pemphigoid (MMP). | BACKGROUND: The use of rituximab for refractory autoimmune blistering diseases is increasing. Data related to rituximab for the treatment of mucous membrane pemphigoid (MMP) are limited.OBJECTIVE: We sought to compare the efficacy of adding rituximab with traditional immunosuppressive therapies in the treatment of MMP.... | ['Academic Medical Centers', 'Adult', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Female', 'Follow-Up Studies', 'Georgia', 'Humans', 'Immunosuppressive Agents', 'Male', 'Middle Aged', 'Pemphigoid, Benign Mucous Membrane... | 26,936,298 | [['N02.278.020'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['E02.319.310'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.35... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Walking speed predicts health status and hospital costs for frail elderly male veterans. | This study evaluated the use of walking speed as an indicator of function and health status in acutely ill, hospitalized, older male veterans. Hospital inpatients in a Department of Veterans Affairs (VA) study of Geriatric Evaluation and Management (GEM) (n = 1,388, age 74.2 +/- 5.7, 98% male) were followed for 1 year.... | ['Aged', 'Female', 'Frail Elderly', 'Gait', 'Health Status', 'Hospital Costs', 'Humans', 'Male', 'United States', 'Veterans', 'Walking'] | 16,320,148 | [['M01.060.116.100'], ['M01.060.116.100.540'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['N03.219.151.400.687', 'N03.219.262.500', 'N05.300.375.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875'], ['M01.930'], ['G11.427.410.568.900', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Infrared spectroscopy with heated attenuated total internal reflectance enabling precise measurement of thermally induced transitions in complex biological polymers. | We report an improved tool for acquiring temperature-resolved fourier transform infrared (FT-IR) spectra of complex polymer systems undergoing thermal transitions, illustrated by application to several phenomena related to starch gelatinization that have proved difficult to study by other means. Starch suspensions from... | ['Amylose', 'Calorimetry, Differential Scanning', 'Crystallization', 'Hot Temperature', 'Kinetics', 'Phase Transition', 'Polymerization', 'Signal-To-Noise Ratio', 'Spectrophotometry, Infrared', 'Spectroscopy, Fourier Transform Infrared', 'Starch', 'Thermodynamics'] | 23,461,675 | [['D09.301.915.361', 'D09.698.365.855.361'], ['E05.196.131.310', 'E05.196.370.310'], ['E05.196.300', 'G02.171'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G01.374.661', 'G02.111.490'], ['G01.645', 'G02.734'], ['G02.750'], [... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Switch from intravenous to enteral moxifloxacin in critically ill patients: a pilot study. | Critically ill patients generally receive moxifloxacin intravenously to achieve rapid bacterial killing. An early switch from intravenous to enteral moxifloxacin may be considered because of its good oral bioavailability in healthy volunteers. Since bioavailability may be altered in critically ill patients due to patho... | ['Administration, Intravenous', 'Administration, Oral', 'Adult', 'Anti-Infective Agents', 'Area Under Curve', 'Aza Compounds', 'Biological Availability', 'Creatine', 'Critical Illness', 'Female', 'Fluoroquinolones', 'Humans', 'Male', 'Microbial Sensitivity Tests', 'Middle Aged', 'Moxifloxacin', 'Pilot Projects', 'Pneum... | 22,804,100 | [['E02.319.267.082'], ['E02.319.267.100'], ['M01.060.116'], ['D27.505.954.122'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D02.145'], ['G03.787.151', 'G07.690.725.129'], ['D02.078.370.280', 'D12.125.373'], ['C23.550.291.625'], ['D03.633.100.810.835.322'], ['B01.050.150.900.649.313.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Squamous cell carcinoma causing blindness and ophthalmoplegia in a cat. | Ophthalmoplegia and blindness caused by squamous cell carcinoma were reported in a cat. Unilateral functional deficits of cranial nerves II, III, IV, and VI and of the sympathetic nerve supply caused blindness, complete ophthalmoplegia, and Horner syndrome. Radiography and computed tomography revealed a proliferating b... | ['Animals', 'Blindness', 'Carcinoma, Squamous Cell', 'Cat Diseases', 'Cats', 'Female', 'Ophthalmoplegia', 'Orbital Neoplasms', 'Skull Neoplasms'] | 2,793,581 | [['B01.050'], ['C10.597.751.941.162', 'C11.966.075', 'C23.888.592.763.941.162'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C10.292.562.750', 'C10.597.622.447', 'C11.590.472', 'C23.888.592.636.447'], ['C04.588.149.721.656', 'C04.588.364.659', 'C05.116... | ['Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of feeding dried distillers' grains with solubles on milk yield and milk composition of cows in mid-lactation and digestibility in sheep. | We evaluated the effect of three sources of dried distillers' grains with solubles (DDGS) in diets of mid-lactating dairy cows on milk production and milk composition and on digestibility in sheep. DDGS from wheat, corn and barley (DDGS1 ), wheat and corn (DDGS2 ) and wheat (DDGS3 ) were studied and compared with a rap... | ['Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Cattle', 'Diet', 'Edible Grain', 'Female', 'Lactation', 'Male', 'Milk', 'Sheep'] | 23,808,383 | [['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G07.203.650.240'], ['A18.024.500.750.500', 'B01.650.160.250', 'B01.650.510.250', 'G07.203.300.300.550', 'G07.203.300.775.500', 'J02.500.300.550', 'J02.500.775.500'], ['G08.686.523', 'G08.686.702.500... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Differential pattern in circulating nitrogen derivatives, lactoferrin, and anti-lactoferrin antibodies in HIV type 1 and HIV type 2 infections. | HIV-1 infection is associated with a dramatic reduction in antioxidative molecules both at the cellular level and in the circulation. This is particularly so for lactoferrin, an iron-binding protein involved in natural defenses (antimicrobial and antiviral activities, etc.) and found in whole secretions, including milk... | ['Antibodies, Antineutrophil Cytoplasmic', 'CD4 Lymphocyte Count', 'Disease Progression', 'Enzyme-Linked Immunosorbent Assay', 'HIV Infections', 'HIV Seropositivity', 'HIV-1', 'HIV-2', 'Humans', 'Lactoferrin', 'Nitric Oxide', 'Nitrites'] | 11,485,621 | [['D12.776.124.486.485.114.323.190', 'D12.776.124.790.651.114.323.190', 'D12.776.377.715.548.114.323.190', 'D23.101.050'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500.150', 'G04.140.107.595.500.150'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The retinofugal pathways in a primitive actinopterygian, the chondrostean Acipenser g?ldenst?dti. An experimental study using degeneration, radioautographic and HRP methods. | Experimental study of the retinofugal pathways in Acipenser g?ldenst?dti was carried out on 109 specimens using 3 experimental tracing methods: Fink-Heimer (after retinal ablation), radioautography (after intraocular injection of tritiated markers) and HRP (after intraocular injection of HRP or iontophoretic deposit of... | ['Animals', 'Autoradiography', 'Axonal Transport', 'Brain', 'Fishes', 'Functional Laterality', 'Horseradish Peroxidase', 'Hypothalamus', 'Nerve Degeneration', 'Retina', 'Superior Colliculi', 'Thalamus', 'Tritium', 'Visual Perception'] | 6,184,126 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['G03.143.355.040', 'G04.392.040', 'G11.561.050'], ['A08.186.211'], ['B01.050.150.900.493'], ['F02.830.297.425', 'G11.561.225.425'], ['D08.811.682.732.512'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['C23.550.737'], ['A09.371.729'], ['A... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effects of iron supplement on metabolism of iron and folic acid in rat liver]. | OBJECTIVE: To study the effects of iron supplement on metabolism of iron and folic acid.METHODS: Thirty-two weanling Sprague-Dawley rats were divided into two groups, iron-normal and iron-deficiency, feeding twice a day with synthetic fodder containing 800 micrograms and less than 20 micrograms iron per day, respective... | ['Animals', 'Animals, Newborn', 'Folic Acid', 'Food, Formulated', 'Iron', 'Liver', 'Male', 'Rats', 'Rats, Sprague-Dawley'] | 10,322,805 | [['B01.050'], ['B01.050.050.282'], ['D03.633.100.733.631.400'], ['G07.203.300.525.350', 'J02.500.525.350'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of insulin therapy on endothelium-dependent dilation in type 2 diabetes mellitus. | Endothelial dysfunction is an early marker of atherosclerosis occurring in patients with type 2 diabetes mellitus. Endothelium-dependent dilation (EDD) has been shown to improve by combined therapy of insulin and metformin. Studies on endothelium-independent vasodilatory capacity, however, have had controversial result... | ['Adult', 'Aged', 'Brachial Artery', 'Diabetes Mellitus, Type 2', 'Endothelium, Vascular', 'Female', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Male', 'Middle Aged', 'Ultrasonography, Interventional', 'Vasodilation'] | 11,835,925 | [['M01.060.116'], ['M01.060.116.100'], ['A07.015.114.139'], ['C18.452.394.750.149', 'C19.246.300'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['M01.060.116.630'], ['E01.370.350.850.855', '... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Laboratory errors for identification of the escherichia coli strains of the serological groups O6 and O25 as acute intestinal infections.] | Were studied the genes encoding the virulence factors of 221 strains: E. coli O6:H1 (194) and E. coli O25:H4 (27), isolated in 2014-2018 from stool samples of children and adults examined according to epidemic indications. Molecular methods included PCR with hybridization-fluorescence and electrophoresis detection of a... | ['Adult', 'Child', 'Escherichia coli', 'Escherichia coli Infections', 'Genes, Bacterial', 'Humans', 'Microbial Sensitivity Tests', 'Phylogeny', 'Serotyping', 'Virulence Factors', 'beta-Lactamases'] | 32,459,896 | [['M01.060.116'], ['M01.060.406'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], [... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Molecular recognition between a new pentacyclic acridinium salt and DNA sequences investigated by optical spectroscopic techniques, proton nuclear magnetic resonance spectroscopy, and molecular modeling. | A pentacyclic acridine, 1H-2,3-dihydroindolizino[7,6,5-kl]acridinium chloride (1), related in structure to tetra- and pentacyclic marine natural products, has previously been shown to induce apoptosis in breast and non-small-cell lung tumor cell lines and shows significant differences in biological potency and antitumo... | ['Acridines', 'Base Sequence', 'Binding Sites', 'Chemical Phenomena', 'Chemistry, Physical', 'DNA', 'Ethidium', 'Indoles', 'Intercalating Agents', 'Models, Molecular', 'Nuclear Magnetic Resonance, Biomolecular', 'Oligodeoxyribonucleotides', 'Spectrometry, Fluorescence', 'Spectrophotometry, Ultraviolet'] | 10,346,892 | [['D03.633.300.046'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['G02'], ['H01.181.529'], ['D13.444.308'], ['D03.633.300.633.416'], ['D03.633.100.473'], ['D27.720.470.410.360'], ['E05.599.595'], ['E05.196.867.519.550'], ['D13.695.578.424.450'], ['E05.196.712.516.600.676', 'E05.196.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Outcomes assessment applied to CLS curriculum revision evaluation. | OBJECTIVE: To describe the application of outcomes measurement and assessment to curriculum revision.SETTING: A baccalaureate level clinical laboratory science (CLS) program in an academic health center.PRACTICE DESCRIPTION: Professional portion of CLS educational program.PRACTICE INNOVATION: Curriculum revision.MAIN O... | ['Academic Medical Centers', 'Curriculum', 'Humans', 'Medical Laboratory Personnel', 'Outcome and Process Assessment, Health Care', 'Schools, Health Occupations', 'Universities'] | 10,165,525 | [['N02.278.020'], ['I02.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.510', 'M01.526.502.500', 'N02.360.510'], ['N04.761.559', 'N05.715.360.575'], ['I02.783.495'], ['I02.783.830', 'J03.832.830']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Evidence that the increased calcium sensitivity of resistance vessels in spontaneously hypertensive rats is an intrinsic defect of their vascular smooth muscle. | We have investigated media thickness and noradrenaline- and calcium-sensitivity of isolated mesenteric resistance vessels from spontaneously hypertensive (SHR) and control Wistar-Kyoto (WKY) rats, which had been treated in various ways. Vessels from untreated SHRs had an increased media thickness and increased noradren... | ['Animals', 'Antihypertensive Agents', 'Blood Pressure', 'Calcium', 'Disease Models, Animal', 'Felodipine', 'Hypertension', 'Hypertension, Renal', 'Mesenteric Arteries', 'Muscle, Smooth, Vascular', 'Nifedipine', 'Norepinephrine', 'Pyridines', 'Rats', 'Rats, Inbred Strains', 'Sympathetic Nervous System', 'Vascular Resis... | 7,297,323 | [['B01.050'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D03.383.725.203.250'], ['C14.907.489'], ['C12.777.419.331', 'C13.351.968.419.331', 'C14.907.489.631'], ['A07.015.114.565'], ['A02.633... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Especial skills: specificity embedded within generality. | Recent evidence suggests that massive amounts of practice of the basketball free throw (a "set shot") results in the development of a specific memory representation that is unique to this one shot distance and angle, and that is distinct from set shots taken at locations other than the free throw line. We termed this u... | ['Adolescent', 'Adult', 'Athletic Performance', 'Basketball', 'Female', 'Humans', 'Male', 'Memory', 'Motor Skills', 'Psychological Theory', 'Space Perception'] | 19,164,838 | [['M01.060.057'], ['M01.060.116'], ['I03.450.642.845.054'], ['I03.450.642.845.117'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['F02.808.260'], ['F02.739'], ['F02.463.593.778']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Time-varying linear and nonlinear parametric model for Granger causality analysis. | Statistical measures such as coherence, mutual information, or correlation are usually applied to evaluate the interactions between two or more signals. However, these methods cannot distinguish directions of flow between two signals. The capability to detect causalities is highly desirable for understanding the cooper... | ['Algorithms', 'Computer Simulation', 'Linear Models', 'Nonlinear Dynamics', 'Time Factors'] | 22,680,497 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['E05.599.850', 'H01.548.675'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Solvent mimicry with methylene carbene to probe protein topography. | The solvent accessible surface area (SASA) of the polypeptide chain plays a key role in protein folding, conformational change, and interaction. This fundamental biophysical parameter is elusive in experimental measurement. Our approach to this problem relies on the reaction of the minimal photochemical reagent diaziri... | ['Amino Acid Sequence', 'Animals', 'Bees', 'Binding Sites', 'Calmodulin', 'Cattle', 'Diazomethane', 'Indicators and Reagents', 'Melitten', 'Methane', 'Methylation', 'Models, Molecular', 'Molecular Sequence Data', 'Protein Conformation', 'Protein Folding', 'Solvents', 'Spectrometry, Mass, Matrix-Assisted Laser Desorptio... | 26,348,271 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.500.131.617.720.500.500.875.387'], ['G02.111.570.120'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['B01.050.150.900.649.313.500.380.271'], ['D02.172.383.383'], ['D27.720.470.410'], ['D12.644.050.550', 'D12.776.543.695.0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A method to assess concomitant cardiac phosphodiesterase inhibition and positive inotropy. | The ability of positive inotropic drugs to inhibit phosphodiesterase was assessed by observance of the potentiation of inotropic responses to the low intrinsic efficacy beta-adrenoceptor partial agonist prenalterol. Previous studies have shown that an increase in tissue stimulus response capability, as is produced for ... | ['1-Methyl-3-isobutylxanthine', 'Adenosine Monophosphate', 'Animals', 'Cardiotonic Agents', 'Guinea Pigs', 'Heart', 'In Vitro Techniques', 'Models, Biological', 'Phosphodiesterase Inhibitors', 'Prenalterol', 'Receptors, Adrenergic, beta'] | 2,450,236 | [['D03.633.100.759.758.824.751.500'], ['D03.633.100.759.646.138.180', 'D13.695.667.138.180', 'D13.695.827.068.180'], ['B01.050'], ['D27.505.954.411.222', 'D27.720.799.080'], ['B01.050.150.900.649.313.992.550'], ['A07.541'], ['E05.481'], ['E05.599.395'], ['D27.505.519.389.735'], ['D02.033.100.624.698.708', 'D02.033.755.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid culture-independent microbial analysis aboard the international space station (ISS) stage two: quantifying three microbial biomarkers. | Abstract A portable, rapid, microbial detection unit, the Lab-On-a-Chip Application Development Portable Test System (LOCAD-PTS), was launched to the International Space Station (ISS) as a technology demonstration unit in December 2006. Results from the first series of experiments designed to detect Gram-negative bac... | ['Biomarkers', 'Exobiology', 'Extraterrestrial Environment', 'Gram-Negative Bacteria', 'Lipopolysaccharides', 'Spacecraft', 'Teichoic Acids'] | 22,984,871 | [['D23.101'], ['H01.158.273.295'], ['G01.060.075.159', 'G16.500.275.240'], ['B03.440'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['J01.937.285.850.900'], ['D09.408.872', 'D09.698.718.825', 'D09.894.847', 'D23.050.161.616.797']] | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Diet and nasopharyngeal carcinoma: a case-control study in Guangzhou, China. | We conducted interviews on 306 histologically confirmed incident cases of nasopharyngeal carcinoma (NPC) occurring in residents of Guangzhou City, China, who were under the age of 50 years, and an equal number of age-, sex-, and neighborhood-matched controls. We also interviewed 110 mothers of patients under age 45 yea... | ['Adult', 'Age Factors', 'Carcinoma', 'China', 'Diet', 'Female', 'Humans', 'Interviews as Topic', 'Middle Aged', 'Mothers', 'Nasopharyngeal Neoplasms', 'Risk Factors', 'Surveys and Questionnaires', 'Urban Population', 'Weaning'] | 2,732,001 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C04.557.470.200'], ['Z01.252.474.164'], ['G07.203.650.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['M01.060.116.630'], ['F01.829.263.500.320.200', 'I01.880.853.15... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
A preliminary study of manipulation under anaesthesia for secondary frozen shoulder following breast cancer treatment. | INTRODUCTION: The aim of this paper is to present the results of manipulation under anaesthesia (MUA) and injection of local anaesthetic and corticosteroid followed by a physiotherapy regime for secondary frozen shoulder after breast cancer treatment (surgery, radiotherapy), and to compare them with a control group.MET... | ['Adult', 'Anesthesia, General', 'Anesthetics, Local', 'Breast Neoplasms', 'Bupivacaine', 'Bursitis', 'Case-Control Studies', 'Combined Modality Therapy', 'Drug Therapy, Combination', 'Exercise Therapy', 'Female', 'Glucocorticoids', 'Humans', 'Hydrotherapy', 'Injections, Intra-Articular', 'Manipulation, Orthopedic', 'M... | 24,780,667 | [['M01.060.116'], ['E03.155.197'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['C04.588.180', 'C17.800.090.500'], ['D02.065.199.239', 'D02.092.146.113.239'], ['C05.550.251'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E02.186'], ['E02.319... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Continuous hydrogen production during fermentation of alpha-cellulose by the thermophillic bacterium Clostridium thermocellum. | Continuous hydrogen (H2) production during fermentation of alpha-cellulose was established using the thermophillic, anaerobic bacterium Clostridium thermocellum ATCC 27405. The objectives of this work were to characterize growth of C. thermocellum, quantify H2 production and determine soluble end-product synthesis patt... | ['Acetates', 'Bioelectric Energy Sources', 'Bioreactors', 'Carbon Dioxide', 'Cellulose', 'Clostridium thermocellum', 'Equipment Design', 'Equipment Failure Analysis', 'Ethanol', 'Fermentation', 'Formates', 'Hydrogen', 'Hydrogen-Ion Concentration', 'Lactic Acid', 'Refuse Disposal', 'Temperature'] | 18,828,175 | [['D02.241.081.018', 'D10.251.400.045'], ['E07.305.124.150'], ['E07.115', 'J01.897.120.115'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['B03.300.390.400.200.770', 'B03.353.625.375.500.770', 'B03.510.415.400.200.770'], ['... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The association of Medicare health care delivery systems with stage at diagnosis and survival for patients with melanoma. | OBJECTIVE: To evaluate differences in the stage at diagnosis and survival for melanoma between the 2 most common types of Medicare health care delivery systems, fee-for-service (FFS) and managed care (health maintenance organizations [HMOs]), in the United States during the period from January 1, 1985, through December... | ['Aged', 'Aged, 80 and over', 'Delivery of Health Care', 'Early Diagnosis', 'Fee-for-Service Plans', 'Female', 'Health Care Surveys', 'Health Maintenance Organizations', 'Humans', 'Male', 'Medicare', 'Melanoma', 'Neoplasm Staging', 'Odds Ratio', 'Prognosis', 'Registries', 'Risk Assessment', 'Skin Neoplasms', 'Socioecon... | 15,967,922 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['N04.590.374', 'N05.300'], ['E01.390'], ['N03.219.442.195', 'N03.219.521.710.305.090', 'N04.452.758.745.225'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N03.219.521.576.343.800.400', 'N03.219.521.576... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Perinatal undernutrition attenuates field excitatory postsynaptic potentials and influences dendritic spine density and morphology in hippocampus of male rat offspring. | Perinatal undernutrition affects the hippocampus, a brain region crucial for learning and memory. However, far less is known about the changes of dendritic spine density and morphology related to hippocampal synaptic plasticity. As dendritic spines are dynamic structures essential for synaptic plasticity and serve as t... | ['Age Factors', 'Animals', 'CA1 Region, Hippocampal', 'Dendritic Spines', 'Excitatory Postsynaptic Potentials', 'Female', 'Long-Term Potentiation', 'Male', 'Malnutrition', 'Maternal Nutritional Physiological Phenomena', 'Pyramidal Cells', 'Rats'] | 23,570,795 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['A08.186.211.180.405.099', 'A08.186.211.200.885.287.500.345.099'], ['A08.675.256.200', 'A11.284.180.225.169', 'A11.671.240.169'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['G11.561.638.350'], [... | ['Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Coherent neuronal ensembles are rapidly recruited when making a look-reach decision. | Selecting and planning actions recruits neurons across many areas of the brain, but how ensembles of neurons work together to make decisions is unknown. Temporally coherent neural activity may provide a mechanism by which neurons coordinate their activity to make decisions. If so, neurons that are part of coherent ense... | ['Animals', 'Brain Mapping', 'Decision Making', 'Electrophysiological Phenomena', 'Excitatory Postsynaptic Potentials', 'Macaca mulatta', 'Male', 'Neurons', 'Parietal Lobe', 'Photic Stimulation', 'Psychomotor Performance', 'Signal Transduction'] | 26,752,158 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.785.373'], ['G07.265'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['A08.675', 'A11.671'], ['A... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Three-dimensional echocardiography in the diagnosis of cardiopathies]. | The ability to visualize with dynamic 3D views the images obtained from the 2D study was the obviously next step in the evolution of echocardiography. Today, thanks to the technological evolution, the capability of obtaining and processing images with computers support has emerged with a great potential. Three-dimensio... | ['Echocardiography, Three-Dimensional', 'Heart Diseases', 'Humans'] | 12,001,843 | [['E01.370.350.130.750.230', 'E01.370.350.400.200', 'E01.370.350.850.220.230', 'E01.370.370.380.220.230'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
NMR detection of adventitious xylose binding to the quorum-sensing protein SdiA of Escherichia coli. | During the solution structure determination of the Escherichia coli quorum-sensing protein SdiA in the presence of N-octanoyl-l-homoserine lactone (HSL), NMR signals were detected in (13)C-filter-(13)C-filter spectra for the bound HSL molecule. An additional set of coupled signals, independent of those of HSL, were als... | ['Escherichia coli', 'Escherichia coli Proteins', 'Ligands', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Molecular Structure', 'Quorum Sensing', 'Trans-Activators', 'Xylose'] | 17,889,538 | [['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['D27.720.470.480'], ['E05.196.867.519'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['G04.085.700', 'G06.550.700'], ['D12.776.260.755', 'D12.776.930.900', 'D12.776.964.925.984'], ['D09.947.875.627.867']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pulmonary hypertension and right heart failure due to severe hypernatremic dehydration. | INTRODUCTION: Neonates are at risk of developing hypernatremic dehydration and its associated complications, such as stroke, dural sinus thrombosis and renal vein thrombosis. Pulmonary hypertension has not been described as a complication of hypernatremia.CASE REPORT: We report a case of a seven-day-old neonate with se... | ['Dehydration', 'Extracorporeal Membrane Oxygenation', 'Fluid Therapy', 'Heart Failure', 'Humans', 'Hypernatremia', 'Hypertension, Pulmonary', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Male'] | 28,553,778 | [['C18.452.950.179', 'C23.550.274'], ['E02.880.301', 'E04.292.451'], ['E02.319.360'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.950.452'], ['C08.381.423', 'C14.907.489.556'], ['M01.060.703.520'], ['C16.614']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Changes in calcium, phosphate, magnesium and sodium content in bones of ovariectomized rats]. | Bilateral ovariectomies (OVX) or sham surgeries-respectively-were performed in two lots of ten female Wistar rats, 90 days old. Food was available ad libitum to sham rats, and it was restricted to OVX ones. At 15, 30, 45 and 90 days, a segment of their tails was sectioned. At 180 days all rats were sacrificed and the l... | ['Animals', 'Body Weight', 'Bone and Bones', 'Calcium', 'Female', 'Magnesium', 'Osteoporosis', 'Ovariectomy', 'Phosphates', 'Rats', 'Rats, Wistar', 'Sodium', 'Time Factors'] | 9,161,458 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A02.835.232', 'A10.165.265'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['C05.116.198.579', 'C18.452.104.579'], ['E... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Psychiatric consultation in the management of patient ambivalence interfering with the doctor-patient relationship. | The author describes states of patient ambivalence as a regressive response to illness that may interfere with the patient-staff alliance. She provides three illustrations of such ambivalence and tells how they were handled by psychiatric consultation in an obstetrical hospital. She describes the characteristics of the... | ['Adult', 'Climacteric', 'Conflict, Psychological', 'Depressive Disorder', 'Female', 'Humans', 'Hyperemesis Gravidarum', 'Middle Aged', 'Obstetrics and Gynecology Department, Hospital', 'Physician-Patient Relations', 'Pregnancy', 'Psychotherapy', 'Referral and Consultation'] | 7,457,639 | [['M01.060.116'], ['G08.686.157', 'G08.686.841.249'], ['F01.658.209'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.703.407.500', 'C23.888.821.937.049.500'], ['M01.060.116.630'], ['N02.278.216.500.968.495', 'N04.452.442.452.422.495'], ['F01.829.401.650.675', 'N05.300.660.625'], ['G08.686.784.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
CD4 mAbs prevent progression of alloactivated CD4+ T cells into the S phase of the cell cycle without interfering with early activation signals. | Knowing that several CD4 mAbs may delay allograft rejection in the absence of circulating CD4+ lymphocyte depletion in vivo, we investigated the mechanisms whereby CD4 mAbs can interfere with the development of alloreactive T cells in the mixed lymphocyte reaction (MLR). In agreement with previous reports, CD4 mAbs of ... | ['Antibodies, Monoclonal', 'CD4 Antigens', 'CD4-Positive T-Lymphocytes', 'Cytokines', 'DNA Primers', 'G1 Phase', 'Gene Expression', 'Humans', 'Lymphocyte Activation', 'Lymphocyte Culture Test, Mixed', 'RNA, Messenger', 'Receptors, Interleukin-2', 'S Phase'] | 8,900,315 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.894.100', 'D23.101.100.894.100'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['D... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Suppression of ocular inflammation in endotoxin-induced uveitis by inhibiting nonproteolytic activation of prorenin. | PURPOSE: A recent study revealed that angiotensin receptor signaling mediates ocular inflammation and neovascularization. It was also found that prorenin undergoes nonproteolytic activation leading to upregulation of the renin-angiotensin system (RAS) when prorenin receptor interacts specifically with the handle region... | ['Animals', 'Antibodies, Blocking', 'Chemokine CCL2', 'Disease Models, Animal', 'Enzyme Activation', 'Enzyme-Linked Immunosorbent Assay', 'Escherichia coli', 'Immunoenzyme Techniques', 'Inflammation', 'Intercellular Adhesion Molecule-1', 'Interleukin-6', 'Leukocytes', 'Lipopolysaccharides', 'Peptide Fragments', 'RNA, M... | 16,723,487 | [['B01.050'], ['D12.776.124.486.485.114.143', 'D12.776.124.790.651.114.143', 'D12.776.377.715.548.114.143'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G02.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cervical cancer with paraaortic involvement: do patients truly benefit from tailored chemoradiation therapy? A retrospective study on 8 French centers. | We retrospectively studied the therapeutic significance of extended-field radiotherapy combined with concurrent platinum-based chemotherapy for the management of cervical carcinoma with paraaortic spread. Treatment response and survival outcomes were evaluated. One hundred and fifteen women were retrospectively studied... | ['Adenocarcinoma', 'Adult', 'Aged', 'Antineoplastic Agents', 'Aorta', 'Brachytherapy', 'Carcinoma, Squamous Cell', 'Chemoradiotherapy', 'Chemotherapy, Adjuvant', 'Cisplatin', 'Disease Progression', 'Disease-Free Survival', 'Female', 'Humans', 'Lymph Node Excision', 'Lymphatic Metastasis', 'Magnetic Resonance Imaging', ... | 26,295,788 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['A07.015.114.056'], ['E02.815.150'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E02.186.079', 'E02.319.164', 'E02.815.160'], ['E02.186.170', 'E02.319.170'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['C23.550.291.656'], ['... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enigmas from the past: M'Intosh's (1885) annelidicolous copepods from the voyage of H.M.S. Challenger. | The type material of four monotypic genera, Leaniricola, Oestrella, Praxillinicola and Trophoniphila (Copepoda, Cyclopoida), described by M'Intosh (1885) from deep water polychaete hosts collected during the H.M.S. Challenger expedition, is re-examined. Leaniricola rotundata M'Intosh (1885) is removed from its floating... | ['Animals', 'Copepoda', 'Female', 'Male', 'Oceans and Seas', 'Polychaeta'] | 27,811,805 | [['B01.050'], ['B01.050.500.131.365.160'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.756'], ['B01.050.500.091.700']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Evaluation of open versus closed urine collection systems and development of nosocomial bacteriuria in dogs. | OBJECTIVE: To determine whether use of a closed urine collection system would decrease the incidence of nosocomial bacteriuria in hospitalized dogs, compared with use of an open urine collection system (used, sterile IV bags).DESIGN: Randomized controlled trial.ANIMALS: 51 hospitalized dogs requiring indwelling urinary... | ['Animals', 'Bacteriuria', 'Cross Infection', 'Dog Diseases', 'Dogs', 'Female', 'Male', 'Specimen Handling', 'Urinary Catheterization'] | 20,632,792 | [['B01.050'], ['C01.915.219', 'C12.777.892.219', 'C13.351.968.892.219'], ['C01.248', 'C23.550.291.875.500'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.225.998', 'E05.200.998'], ['E01.370.390.820', 'E02.148.947', 'E05.157.500']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ablation of LKB1 in the heart leads to energy deprivation and impaired cardiac function. | Energy deprivation in the myocardium is associated with impaired heart function and increased morbidity. LKB1 is a kinase that is required for activation of AMP-activated protein kinase (AMPK) as well as 13 AMPK-related protein kinases. AMPK stimulates ATP production during ischemia and prevents post-ischemic dysfuncti... | ['Aerobiosis', 'Animals', 'Cells, Cultured', 'Energy Metabolism', 'Gene Deletion', 'Heart', 'Heart Diseases', 'Intracellular Signaling Peptides and Proteins', 'Mice', 'Mice, Knockout', 'Muscles', 'Myocardial Ischemia', 'Myocardium', 'Organ Culture Techniques', 'Organ Specificity', 'Protein-Serine-Threonine Kinases', 'S... | 20,441,792 | [['G02.111.017', 'G03.049'], ['B01.050'], ['A11.251'], ['G03.295'], ['G05.365.590.762.320', 'G05.558.800.320'], ['A07.541'], ['C14.280'], ['D12.644.360', 'D12.776.476'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.313.9... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rhodium and iridium salts inhibit proliferation and induce DNA damage in rat fibroblasts in vitro. | Environmental concentration of the platinum group elements is increased in the last years due to their use in automobile catalytic converters. Limited data are available on the effects of such elements at a cellular level and on their toxicity, especially for rhodium and iridium which have been more recently introduced... | ['Animals', 'Apoptosis', 'Cell Cycle', 'Cell Cycle Proteins', 'Cell Line', 'Cell Proliferation', 'Cell Survival', 'Comet Assay', 'DNA Damage', 'Fibroblasts', 'Iridium', 'Rats', 'Rhodium'] | 22,521,858 | [['B01.050'], ['G04.146.954.035'], ['G04.144'], ['D12.776.167'], ['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.560.150'], ['G05.200'], ['A11.329.228'], ['D01.268.556.401', 'D01.268.956.280', 'D01.552.544.401'], ['B01.050.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Therapeutic strategies in the surgical treatment of Hangman's fractures]. | Hangman's fractures are located in the region between facets of the axis, which are accompanied by an increasing rate recently. However,there are no uniform standards for the treatment, especially for the treatment of fractures of types II and IIa because the operative approaches which include anterior and posterior ar... | ['Cervical Vertebrae', 'Humans', 'Spinal Fractures'] | 19,753,974 | [['A02.835.232.834.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.117.500.500', 'C26.404.812']] | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Local direction of edge motion causes and abolishes the barberpole illusion. | The perceived direction of motion of a one-dimensional grating is measured in straight-edged rectangular and indented rectangular apertures. It is shown that the perceived direction of motion of the pattern is largely determined by the directions of motion at the edges, rather than by the aspect ratio or global shape o... | ['Humans', 'Motion Perception', 'Optical Illusions', 'Pattern Recognition, Visual', 'Time Factors'] | 8,273,299 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.932.567'], ['F02.463.593.446.659'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['G01.910.857']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quetiapine in the successful treatment of schizophrenia with comorbid alcohol and drug dependence: a case report. | BACKGROUND: Excluding nicotine and caffeine dependence, almost 50% of individuals with schizophrenia also meet the criteria for substance abuse or dependence. Comorbid drug abuse presents complications to the effective treatment of these patients because they have increased psychotic symptoms and poorer treatment compl... | ['Adult', 'African Americans', 'Antipsychotic Agents', 'Benzodiazepines', 'Contraindications', 'Diagnosis, Dual (Psychiatry)', 'Dibenzothiazepines', 'Humans', 'Male', 'Olanzapine', 'Pirenzepine', 'Priapism', 'Quetiapine Fumarate', 'Schizophrenia', 'Substance-Related Disorders'] | 12,906,345 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['D03.633.100.079.080'], ['E02.208'], ['E01.190'], ['D02.886.680.702.500', 'D03.633.300.276'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.079.080.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Temporal effects of vascular endothelial growth factor and 3,5-cyclic monophosphate on blood-brain barrier solute permeability in vivo. | To test the hypothesis that vascular endothelial growth factor (VEGF) can transiently increase the blood-brain barrier permeability, P, as for peripheral microvessels and that the elevation of 3,5-cyclic monophosphate (cAMP) levels can inhibit the VEGF-induced acute hyperpermeability, we employed multiphoton microscopy... | ['Analysis of Variance', 'Animals', 'Blood-Brain Barrier', 'Capillary Permeability', 'Cerebrovascular Circulation', 'Cyclic AMP', 'Dextrans', 'Dose-Response Relationship, Drug', 'Female', 'Fluorescein', 'Fluorescein-5-isothiocyanate', 'Rats', 'Rats, Sprague-Dawley', 'Vascular Endothelial Growth Factor A'] | 25,066,133 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A07.035', 'A08.186.211.035'], ['G03.143.330', 'G09.330.165'], ['G09.330.100.159'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D05.750.078.562.272', 'D09.698.365.272'], ['G07.690.77... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Study of pre-operative chemotherapeutic methods for colonic cancer--the concentration in blood and tissues after pre-operative administration of UFT]. | As one of the fundamental studies of the pre-operative chemotherapeutic methods in 22 cases with colonic cancer, we studied a progress of the concentration in blood and concentration in tissues including those in the portal vein after administration of UFT. The concentration of 5-FU in blood reached to the peak at 2 ho... | ['Administration, Oral', 'Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Colonic Neoplasms', 'Drug Administration Schedule', 'Female', 'Humans', 'Male', 'Middle Aged', 'Preoperative Care', 'Tegafur', 'Uracil'] | 1,929,448 | [['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Quercetin Reduces Cortical GABAergic Transmission and Alleviates MK-801-Induced Hyperactivity. | An imbalance between neuronal excitation and inhibition represents a core feature in multiple neuropsychiatry disorders, necessitating the development of novel strategies to calibrate the excitatory-inhibitory balance of therapeutics. Here we identify a natural compound quercetin that reduces prefrontal cortical GABAer... | ['Animals', 'Antipsychotic Agents', 'Cells, Cultured', 'Dizocilpine Maleate', 'Excitatory Amino Acid Antagonists', 'Humans', 'Hyperkinesis', 'Locomotion', 'Male', 'Mice, Inbred C57BL', 'Neurons', 'Prefrontal Cortex', 'Quercetin', 'Receptors, GABA-A', 'Synaptic Transmission', 'gamma-Aminobutyric Acid'] | 30,057,312 | [['B01.050'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['A11.251'], ['D02.455.426.559.847.181.384.380', 'D04.615.181.384.380'], ['D27.505.519.625.190.300', 'D27.505.696.577.190.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.350.350', 'C23.888.592.350.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characteristics of cocaine users in a private inpatient treatment setting. | Patient records were reviewed from an eighteen-month period of a private hospital adult addictive disease unit. Of 667 consecutive admissions, sixty-five (49 males, 16 females) were diagnosed with cocaine abuse or dependence; 38 percent were from rural areas. Although mean age of males and females was similar, males ha... | ['Adult', 'African Americans', 'Chi-Square Distribution', 'Cocaine-Related Disorders', 'Female', 'Hospitals, Private', 'Hospitals, Psychiatric', 'Humans', 'Kentucky', 'Male', 'Retrospective Studies', 'Rural Population'] | 10,429,356 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C25.775.300', 'F03.900.300'], ['N02.278.421.481'], ['N02.278.421.556.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.075.400', 'Z01.107.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Chemical patterning of ultrathin polymer films by direct-write multiphoton lithography. | We applied 2-photon laser ablation to write subdiffraction nanoscale chemical patterns into ultrathin polymer films under ambient conditions. Poly(ethylene glycol) methacrylate brush layers were prepared on quartz substrates via surface-initiated atom-transfer radical polymerization and ablated to expose the underlying... | ['Microscopy, Atomic Force', 'Microscopy, Confocal', 'Nanotechnology', 'Polyethylene Glycols', 'Titanium'] | 21,452,872 | [['E01.370.350.515.666.400', 'E05.595.666.400'], ['E01.370.350.515.395', 'E05.595.395'], ['H01.603', 'J01.897.520.600'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
p53 target Siva regulates apoptosis in ischemic kidneys. | The role of p53 in inducing apoptosis following acute kidney injury is well-established; however, the molecular mechanisms remain largely unknown. We report here that the p53 proapoptotic target Siva and its receptor CD27, a member of the tumor necrosis factor receptor family, are upregulated following renal ischemia-r... | ['Analysis of Variance', 'Animals', 'Apoptosis', 'Apoptosis Inducing Factor', 'Apoptosis Regulatory Proteins', 'Caspase 8', 'Caspase 9', 'Cell Hypoxia', 'Cytochromes c', 'Disease Models, Animal', 'Enzyme Activation', 'Intracellular Signaling Peptides and Proteins', 'Kidney', 'LLC-PK1 Cells', 'Male', 'Mice', 'Mice, 129 ... | 21,307,125 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G04.146.954.035'], ['D08.811.682.608.047', 'D12.644.360.075.311', 'D12.776.157.687.063', 'D12.776.331.161', 'D12.776.476.075.311', 'D12.776.660.720.063'], ['D12.644.360.075', 'D12.776.476.075'], ['D08.811.277.656.262.500.126.550.800', 'D... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of indomethacin on leukotriene4-induced histamine hyperresponsiveness in asthmatic subjects. | The effect of indomethacin on the capacity of LTE4 to enhance airway histamine responsiveness was evaluated in eight mild asthmatic subjects. Subjects attended the laboratory on three separate pairs of study days when inhalation challenges with methacholine or LTE4 were performed and the airway responses to histamine w... | ['Adult', 'Airway Resistance', 'Asthma', 'Bronchial Hyperreactivity', 'Bronchial Provocation Tests', 'Female', 'Histamine', 'Humans', 'Indomethacin', 'Leukotriene E4', 'Male', 'Methacholine Chloride', 'SRS-A'] | 1,333,740 | [['M01.060.116'], ['E01.370.386.700.050', 'G09.772.060'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C08.127.210'], ['E01.370.386.700.125'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of the dual route theory of reading: a metanalysis of 35 neuroimaging studies. | Numerous studies concerned with cerebral structures underlying word reading have been published during the last decade. A few controversies, however, together with methodological or theoretical discrepancies between laboratories, still contribute to blurring the overall view of advances effected in neuroimaging. Carrie... | ['Clinical Trials as Topic', 'Cluster Analysis', 'Cognition', 'Functional Laterality', 'Humans', 'Magnetic Resonance Imaging', 'Nervous System', 'Nervous System Physiological Phenomena', 'Occipital Lobe', 'Reading', 'Stereotaxic Techniques', 'Temporal Lobe', 'Tomography, Emission-Computed', 'Visual Cortex', 'Visual Per... | 14,568,445 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['F02.463.188'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A08'], ['G11.561'], ['A08.186.211.200.88... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
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