Datasets:
yirenc
/
guidelines1K

Dataset card Data Studio Files
xet
 Community
1
clean_text
stringlengths
138
404k
Calcium carbimide # Overview Calcium carbimide, sold as the citrate salt under the trade name Temposil, is an alcohol sensitizing agent. Its effects are similar to the drug disulfiram (Antabuse) in that it interferes with the normal metabolism of alcohol by preventing the breakdown of the metabolic byproduct acetaldeh...
Ergotamine and caffeine (oral) # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational c...
Abrupt closure case 26 # Abrupt Closure ## Pre-intervention Shown below is a pre-intervention angiogram with significant diffuse in-stent lesion in the SVG to LAD. ## Intervention Shown below is an angiogram with ongoing intervention on the significant lesion described above. ## Post-intervention Shown below is a p...
TIP39 Tuberoinfundibular peptide of 39 residues is a protein that in humans is encoded by the PTH2 gene. TIP39 is related to parathyroid hormone (PTH; MIM 168450) and PTH-related protein (PTHRP; MIM 168470) and is a ligand for PTH receptor-2 (PTHR2; MIM 601469) (John et al., 2002). The molecular interaction of TIP39 wi...
Apraxia Synonyms and keywords: Dyspraxia # Overview Praxis, a Greek work for act, work, or deed, is the ability to perform the learned movements. It usually comprises of three components, namely, ideation (what to do), motor planning (how to do), and execution (performing the movement correctly), that results in purpo...
Rituximab for the treatment of relapsed or refractory stage III or IV follicular non-Hodgkin's lymphoma Evidence-based recommendations on rituximab for treating relapsed or refractory stage III or IV follicular non-Hodgkin's lymphoma in adults. # Guidance This guidance replaces 'The clinical effectiveness and cost ef...
Zap1p gene transcriptions "Zinc homeostasis in yeast is controlled primarily through the regulation of zinc uptake. Transcription of the ZRT1 and ZRT2 zinc transporters increases in zinc-limited cells, and this induction is dependent on the ZAP1 gene. Expression of ZAP1 itself increases in zinc-limited cells. (ZREs) ...
# GUIDELINE OBJECTIVES To make recommendations with respect to the role of adjuvant systemic chemotherapy in stage II and III colon cancer patients who have undergone complete resection with curative intent. # TARGET POPULATION The target population consists of adult patients with stage II and III colon cancer who hav...
Paul G. Rogers Society for Global Health Research Established by Research!America in July 2006, the mission of the Paul G. Rogers Society for Global Health Research is to increase awareness of -- and make the case for greater U.S. investment in --- research to fight diseases that affect the world's poorest nations; thi...
DCLRE1A DNA cross-link repair 1A protein is a protein that in humans is encoded by the DCLRE1A gene. DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1A is one of several evolutionarily conserved genes involved in repair of inter...
Sleep paralysis # Overview Sleep paralysis is a condition characterized by temporary paralysis of the body shortly after waking up (known as hypnopompic paralysis) or, less often, shortly before falling asleep (known as hypnagogic paralysis). Physiologically, it is closely related to the paralysis that occurs as a nat...
Prochlorococcus Prochlorococcus is a genus of very small (0.6 µm) marine cyanobacteria with an unusual pigmentation (chlorophyll b) belonging to photosynthetic picoplankton. It is probably the most abundant photosynthetic organism on Earth. # Overview Although there had been several earlier records of very small chlor...
Sandbox ammu save Editing West nile virus historical perspective # Overview WNV was first isolated in 1937 in Uganda from a hospitalized patient who presented with isolated fever. Between 1950 and 1960, small villages in the Mediterranean basin had repeated outbreaks, especially in Israel and Egypt. These outbreaks al...
Osmium tetroxide Osmium tetroxide is the chemical compound with the formula OsO4. The compound is noteworthy for its many uses, despite the rarity of osmium. It also has a number of interesting properties, one being that the solid is volatile. # Physical properties Osmium tetroxide exists as a pale yellow-brown crys...
NFATC4 Nuclear factor of activated T-cells, cytoplasmic 4 is a protein that in humans is encoded by the NFATC4 gene. # Function The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic c...
Cefoxitin clinical pharmacology # CLINICAL PHARMACOLOGY ## Clinical Pharmacology Following an intravenous dose of 1 gram, serum concentrations were 110 mcg/mL at 5 minutes, declining to less than 1 mcg/mL at 4 hours. The half-life after an intravenous dose is 41 to 59 minutes. Approximately 85 percent of cefoxitin is...
Dietary fiber # Overview Dietary fibers are the indigestible portion of plant foods that move food through the digestive system, absorbing water and making defecation easier. Dietary fiber consists of non-starch polysaccharides such as cellulose and many other plant components such as dextrins, inulin, lignin, waxes, ...
Avatrombopag for treating primary chronic immune thrombocytopenia Evidence-based recommendations on avatrombopag (Doptelet) for treating primary chronic immune thrombocytopenia in adults. # Recommendations Avatrombopag is recommended, within its marketing authorisation, as an option for treating primary chronic immun...
Endoscopic thoracic sympathectomy for primary facial blushing # Recommendations Current evidence on the efficacy and safety of endoscopic thoracic sympathectomy (ETS) for primary facial blushing is adequate to support the use of this procedure with normal arrangements for clinical governance, consent and audit. Clinic...
Benign paroxysmal torticollis # Overview Benign paroxysmal torticollis (BPT) is a rare medical disorder affecting infants. # Symptoms and Characteristics The defining characteristic of BPT is a tilting of an infant’s head in recurrent episodes, for varying periods of time. Furthermore, the child’s trunk may bend in t...
Voice therapy (trans) Voice therapy or voice training refers to any non-surgical technique used to improve or modify the human voice. Because voice is a gender cue, transsexual women frequently undertake voice therapy as a part of gender transition in order to make their voices sound female, and therefore increase thei...
Vascular surgery Vascular surgery is a subspecialty of general surgery in which diseases of the vascular system, or arteries and veins, are managed, largely via surgical intervention, and was originally founded by Dr. Clyde Otis Hagood Jr. The vascular surgeon is trained in the diagnosis and management of diseases aff...
Buprenorphine Sublingual and Buprenorphine and Naloxone Sublingual (patient information) # Why this medication is prescribed Buprenorphine (Subutex) and buprenorphine and naloxone (Suboxone) are used to treat opioid dependence (addiction to opioid drugs, including heroin and narcotic painkillers). Buprenorphine is in ...
Longitudinal studies # Overview A longitudinal study is a correlational research study that involves repeated observations of the same items over long periods of time — often many decades. It is a type of observational study. Longitudinal studies are often used in psychology to study developmental trends across the l...
CRYBB2 Beta-crystallin B2 is a protein that in humans is encoded by the CRYBB2 gene. # Function Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. ...
Local anesthetic # Overview A local anesthetic is a drug that causes reversible local anesthesia and a loss of nociception. When it is used on specific nerve pathways (nerve block), effects such as analgesia (loss of pain sensation) and paralysis (loss of muscle power) can be achieved. Clinical local anesthetics belo...
Ipidacrine # Overview Ipidacrine (Neiromidin) is a novel substance synthesized by the National Research Center for Biologically Active Compounds in the Russian Federation. This compound contains the structure of 4-aminopyridine and is structurally very similar to tacrine. Ipidacrine is a reversible acetylcholinesteras...
Emergent stress testing in young people # Overview Stress testing has frequently been used to assess adult patients with suspected or known coronary artery disease (CAD) based on pre-test probability. Pre-test probability is the assessment of a patient and their likelihood of CAD based on clinical history and symptoms...
KvLQT1 Kv7.1 (KvLQT1) is a potassium channel protein whose primary subunit in humans is encoded by the KCNQ1 gene. Kv7.1 is a voltage-gated potassium channel present in the cell membranes of cardiac tissue and in inner ear neurons among other tissues. In the cardiac cells, Kv7.1 mediates the IKs (or slow delayed rect...
Argon # Overview Argon (Template:PronEng) is a chemical element designated by the symbol Ar. Argon has atomic number 18 and is the third element in group 18 of the periodic table (noble gases). Argon is present in the Earth's atmosphere at slightly less than 1%, making it the most common noble gas on Earth. Its full...
Polyhydramnios (patient information) For the WikiDoc page for this topic, click here # Overview Polyhydramnios is the presence of excessive amniotic fluid surrounding the unborn infant. # Considerations - Amniotic fluid is a clear, slightly yellowish liquid that surrounds the unborn baby (fetus) during pregnancy. It ...
Zinc sulfate # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc ...
Dust cell A dust cell (or alveolar macrophage) is a type of macrophage found in the pulmonary alveolus, near the pneumocytes, but separated from the wall. Activity of the dust cells is relatively high, because they are located at one of the major boundaries between the body and the outside world. Dust cells are another...
Moyamoya disease overview Please help WikiDoc by adding content here. It's easy! Click here to learn about editing. # Overview Moyamoya syndrome is a disease in which certain arteries in the brain are constricted. Blood flow is blocked by the constriction, and also by blood clots (thrombosis).The blood vessels dev...
Isotopes of nickel Naturally occurring nickel (Ni) is composed of 5 stable isotopes; 58Ni, 60Ni, 61Ni, 62Ni and 64Ni with 58Ni being the most abundant (68.077% natural abundance). 18 radioisotopes have been characterised with the most stable being 59Ni with a half-life of 76,000 years, 63Ni with a half-life of 100.1 ye...
Cromolyn (nasal) # Disclaimer WikiDoc MAKES NO GUARANTEE OF VALIDITY. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on Wiki...
Water softening A water softener reduces the dissolved calcium, magnesium, and to some degree manganese and ferrous iron ion concentration in hard water. (A common water softener is sodium carbonate; formula Template:SodiumTemplate:Carbonate.) These "hardness ions" cause three major kinds of undesired effects. Most v...
Battered person syndrome # Overview Battered person syndrome is a physical and psychological condition that is classified as ICD-9 code 995.81 "Battered person syndrome" NEC or otherwise included within DSM-IV as a sub-category of post-traumatic stress disorder. This condition has been used as a defense by women who h...
Constant visual observation # Overview Constant visual observation, often abbreviated to "constant visual", is a term used in various mental health services, prisons and special schools to describe the status of a prisoner or patient who poses a threat to himself or a third party, and must therefore be kept under cons...
Cat eye syndrome # Overview Cat Eye Syndrome is a very rare malformation involving Chromosome 22. The short arm (p) and a small section of the long arm (q) are present three (trisomic) or four times (tetrasomic) instead of the usual two times. The additional chromosome 22 usually arises spontaneously (de novo), though...
Direct pathway of movement The striatum modulates movement by two pathways: a direct pathway and an indirect pathway. In the direct pathway, striatal neurons directly inhibit neurons in the globus pallidus internus, which reduces the inhibition of the thalamic neurons responsible for excitation of the premotor cortex. ...
ZP4 Zona pellucida sperm-binding protein 4, ZP-4 or avilesine, named after its discoverer Manuel Avilés Sánchezis a protein that in humans is encoded by the ZP4 gene. # Function The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoprot...
Practice Guidelines for the Management of Community-Acquired Pneumonia in Adults Executive Summary signs, and normal mental status. In step 2, patients not assigned to risk class I are stratified in classes II-V on the basis of points assigned for 3 demographic variables (age, sex, and nursing home residency), 5 comor...
Cystic fibrosis overview # Overview Cystic fibrosis is an autosomal recessive disease that caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The genetic mutation result in defective transport of chloride, and secondarily sodium and eventually abnormal viscous mucoid secretions...
Navigational images # overview Although not a 'feature' of the MediaWiki software, an image can be made to link to a specified page if desired. Some people find trawling through this page understandably confusing, so here is the short version: - You can use the re-direct feature on an image page, but when used, the ta...
Elbow The elbow-joint is a ginglymus or hinge joint. Three bones form the elbow joint: the humerus of the upper arm, and the paired radius and ulna of the forearm. The bony prominence at the very tip of the elbow is the olecranon process of the ulna. # Movements Two main movements are possible at the elbow: - The hing...
Primary mediastinal large B-cell lymphoma overview # Overview Primary mediastinal large B-cell lymphoma (PMBCL) is a subtype of diffuse large B-cell lymphoma (DLBCL). It is also considered a distinct type of non-Hodgkin lymphoma (NHL) in the World Health Organization (WHO) classification system. It occurs in the thymu...
African American Study Of Kidney Disease And Hypertension # Complete Title of Study African American Study of Kidney Disease and Hypertension ABPM Pilot Study # Study Acronym (The trial's abbreviation if there is one) AASK # Principal Investigator, Co-investigators, and Collaborating Institutions Collaborator: Natio...
Angiopoietin 1 Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this ...
Chorionic villi # Overview Chorionic villi are villi that sprout from the chorion in order to give a maximum area of contact with the maternal blood. Embryonic blood is carried to the villi by the branches of the umbilical arteries, and after circulating through the capillaries of the villi, is returned to the embryo ...
Brain stem The brain stem is the lower part of the brain, adjoining and structurally continuous with the spinal cord. Most sources consider the pons, medulla oblongata, and midbrain all to be part of the brainstem. Differentiation of the brain stem from the cerebrum is complex, with regard to both anatomy and taxonomy....
Zoon's balanitis Synonyms and keywords: ZB, Plasma cell balanitis # Overview Zoon's balanitis is a rare non-veneral idiopathic chronic benign inflammatory mucositis of genitalia. In 1952, for the first time in medical literature, Zoon recognized a distinct entity in patients with chronic balanitis,and named it has bal...
Social work knowledge building The history of social work is a history plagued by a fundamental question – is social work a profession? This debate can be traced back to the early 20th century debate between Mary Richmond's Charity Organization Society (COS) and Jane Addams's Settlement House Movement. The essence of t...
Isthmus An isthmus (Template:IPAEng, Template:Lang-el, plural isthmuses or isthmi) is a narrow strip of land that is bordered on two sides by water and connects two larger land masses. It is the inverse of a strait (which lies between two land masses and connects two larger bodies of water). Isthmi are naturally good...
Mepolizumab for treating severe eosinophilic asthma Evidence-based recommendations on mepolizumab (Nucala) for treating severe eosinophilic asthma in adults. # Recommendations Mepolizumab, as an add-on therapy, is recommended as an option for treating severe refractory eosinophilic asthma, only if: it is used for adu...
Coptis aspleniifolia Coptis aspleniifolia, commonly known as Fern-Leaved Goldthread, is found in the northern two-thirds of British Columbia, in Alaska, and along the Cascades into Washington and is a native plant of the Coast (temperate) Forest Region. It is often found in the understory of the herb layer of carnifer...
Wiskott-Aldrich syndrome Synonyms and keywords: Aldrich syndrome # Overview Wiskott-Aldrich syndrome (WAS) is a rare X-linked recessive disease characterized by eczema, thrombocytopenia (low platelet counts), immune deficiency, and bloody diarrhea (due to the low platelet counts). It is also sometimes called the ecze...
User contributions # Overview User contributions pages list the edits that a particular user has made. These pages are project specific, so a user contributions page for meta will not show the edits that user has made to Wikipedia or any other project. Checking your contributions is useful to refresh your memory about...
Molecule In chemistry, a molecule is defined as a sufficiently stable electrically neutral group of at least two atoms in a definite arrangement held together by strong chemical bonds. In organic chemistry and biochemistry, the term molecule is used less strictly and also is applied to charged organic molecules and bio...
Human height # Overview Human height varies according to both "nature" and "nurture". The particular human genome that an individual inherits is a large part of the first variable (nature), and a combination of health and environmental factors present before adulthood (when growth stops) are a major part of the second...
Public domain Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us to indicate your interest in serving either as an Editor-In-Chief of the entir...
Abdominal aortic aneurysm: diagnosis and management This guideline covers diagnosing and managing abdominal aortic aneurysms. It aims to improve care by helping people who are at risk to get tested, specifying how often to monitor asymptomatic aneurysms, and identifying when aneurysm repair is needed and which procedu...
Quinine Sulfate contraindications # Contraindications QUALAQUIN is contraindicated in patients with the following: - Prolonged QT interval. One case of a fatal ventricular arrhythmia was reported in an elderly patient with a prolonged QT interval at baseline, who received quinine sulfate intravenously for P. falciparu...
Paraphilia Synonyms and keywords: Fetishism, Voyeurism, Zoophilia, Pedophilia, Sexual perversion, Zoophilism, Abnormal sexual activity # Overview Paraphilias are characterized by severe deviant sexual desire or urge resulting in actions that may cause significant impairment in functioning as well as distress (for ones...
Emergency medical technician-basic Emergency Medical Technician-Basic (EMT-B) is the entry level of prehospital emergency medical provider in the United States. EMT-Bs are employed in a variety of industries. EMT-Bs are not trained to provide definitive medical care, but instead focus on rapid in-field treatment and tr...
Arachnodactyly Arachnodactyly, also known as spider fingers refers to abnormally long and slender fingers. Toes and feet are also usually affected. # Differential Diagnosis of Diseases Associated with Arachnodactyly In alphabetical order: - Achard Syndrome - Homocystinuria - Lutembacher's Syndrome - Marfan's Syndrom...
ST6GAL1 Beta-galactoside alpha-2,6-sialyltransferase 1 is an enzyme that in humans is encoded by the ST6GAL1 gene. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein, which is normally fou...
Alkaptonuria (patient information) For the WikiDoc page for this topic, click here # Overview Alkaptonuria is a rare condition in which a person's urine turns a dark brownish-black color when exposed to air. # What are the symptoms of Alkaptonuria? Urine in an infant's diaper may darken and can turn almost black afte...
depar depar depar depar department of health and human ser tment of health and human ser tment of health and human ser tment of health and human ser tment of health and human services vices vices vices vices# Background This report presents CDC's recommendations for case definitions for Acute Idiopathic Pulmonary Hemor...
Hydroxymethylglutaryl-CoA synthase In molecular biology, Hydroxymethylglutaryl-CoA synthase or HMG-CoA synthase EC 2.3.3.10 is an enzyme which catalyzes the reaction in which Acetyl-CoA condenses with acetoacetyl-CoA to form 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA). It is the second reaction in the mevalonate-dependent...
Green sulfur bacteria The green sulfur bacteria are a family of obligately anaerobic photoautotrophic bacteria. Most closely related to the nonetheless distant Bacteroidetes, they are accordingly assigned their own phylum. Green sulfur bacteria are non-motile (except Chloroherpeton thalassium, which may glide) and come...
TMEM249 TMEM 249 is a protein that in humans is encoded by the C8orfk29 gene. # Gene # Locus TMEM 249 is located near the end of the long arm of chromosome 8 in humans. # Common aliases TMEM 249 is also known as C8orfk29. # Primary sequence & variants/isoforms The primary sequence found at NCBI and Aceview on NCBI ...
PEDF Pigment epithelium-derived factor (PEDF) also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functions. Found in vertebrates, this 50 kDa protein is being researched as a therapeutic candidate for treatment of such conditions as cho...
Aarskog-Scott syndrome Synonyms and Keywords: Aarskog disease, Aarskog-Scott syndrome, AAS, Faciodigitogenital syndrome, Faciogenital dysplasia, FGDY, Scott Aarskog syndrome # Overview Aarskog-Scott syndrome is a rare inherited disease distinguish by short stature, facial abnormalities, skeletal and genital anomalies....
Wilson disease protein Wilson disease protein (WND), also known as ATP7B protein, is a copper-transporting P-type ATPase which is encoded by the ATP7B gene. The ATP7B protein is located in the trans-Golgi network of the liver and brain and balances the copper level in the body by excreting excess copper into bile and p...
EHR Resolution July 4, 2015 We, the undersigned practicing physicians of America, do warrant the following: Whereas the "Meaningful Use of Electronic Health Records" program, as designed by a commission, composed of 23 persons, 9 of whom were physicians, two of whom were practicing, enacted by the Hitech Act of 2009, w...
Immune system An immune system is a collection of mechanisms within an organism that protects against disease by identifying and killing pathogens and tumor cells. It detects a wide variety of agents, from viruses to parasitic worms, and needs to distinguish them from the organism's own healthy cells and tissues in ord...
Crizotinib for treating ROS1-positive advanced non-small-cell lung cancer Evidence-based recommendations on crizotinib (Xalkori) for treating ROS1-positive advanced non-small-cell lung cancer in adults. # Recommendations Crizotinib is recommended for use within the Cancer Drugs Fund as an option for treating ROS1‑pos...
Taho Tahô is a Philippine snack food made of fresh soft/silken tofu, arnibal (brown sugar syrup), and sago "pearls" (similar to tapioca pearls). This staple comfort food is a signature sweet and can be found all over the country. # History The history of taho is debatable, but early records suggest it may trace its or...
Cochlea The cochlea is the auditory portion of the inner ear. Its core component is the Organ of Corti, the sensory organ of hearing, which is distributed along the partition separating fluid chambers in the coiled tapered tube of the cochlea. The name is from the Latin for snail, which is from the Greek kokhlias "sna...
Acute Lymphoblastic Leukemia (ALL) is a highly aggressive hematological -malignancy resulting from the proliferation and expansion of lymphoid blasts in the blood, bone marrow and other organs. 1 ALL occurs with a bimodal distribution with an early peak in children 4 -5 years old followed by a second peak at ~ 50 years...
Peptidoglycan Peptidoglycan, also known as murein, is a polymer consisting of sugars and amino acids that forms a mesh-like layer outside the plasma membrane of eubacteria. The sugar component consists of alternating residues of β-(1,4) linked N-acetylglucosamine and N-acetylmuramic acid residues. Attached to the N-...
ROS1 Proto-oncogene tyrosine-protein kinase ROS is an enzyme that in humans is encoded by the ROS1 gene. # Function This proto-oncogene, highly expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral...
Monomelic amyotrophy Monomelic amyotrophy (also known as MMA, Hirayama's disease, Sobue disease or Juvenile nonprogressive amyotrophy) is an untreatable, focal, lower motor neuron disease that primarily affects young (15 - 25 year-old) males in India and Japan. MMA is marked by insidious onset of muscular atrophy, whi...
Cystic duct # Overview The cystic duct is the short duct that joins the gall bladder to the common bile duct. It usually lies next to the cystic artery. It is of variable length. It contains a 'spiral valve', which does not provide much resistance to the flow of bile. # Function Bile can flow in both directions bet...
Kiaa1107 KIAA1107 is a protein that in humans is encoded by the KIAA1107 gene. KIAA1107 is a Serine-rich protein, whose expression was found to increase in white matter of Multiple Sclerosis brain lesions. # Gene ## General Information KIAA1107 is a protein encoding gene, located on chromosome 1 in Homo sapiens. It...
FLNB Filamin B, beta (FLNB), also known as Filamin B, beta (actin binding protein 278), is a cytoplasmic protein which in humans is encoded by the FLNB gene. FLNB regulates intracellular communication and signalling by cross-linking the protein actin to allow direct communication between the cell membrane and cytoskele...
Nasal Congestion overview Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing. # Overview Nasal congestion is the blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels. It is also known as nasal blockage, nasa...
miR-134 miR-134 is a family of microRNA precursors found in mammals, including humans. MicroRNAs are typically transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. The excised region or, mature product, of the miR-134 precursor is the microRNA mir-134...
Rosenhan experiment # Background The Rosenhan experiment was a famous experiment into the validity of psychiatric diagnosis conducted by David Rosenhan in 1972. It was published in the journal Science under the title "On being sane in insane places". Rosenhan's study consisted of two parts. The first involved the use ...
Bile salt-dependent lipase Bile salt-dependent lipase (or BSDL), also known as carboxyl ester lipase (or CEL) is an enzyme produced by the adult pancreas and aids in the digestion of fats. Bile salt-stimulated lipase (or BSSL) is an equivalent enzyme found within breast milk. BSDL has been found in the pancreatic secre...
Hydrocele overview Steven C. Campbell, M.D., Ph.D. # Overview A hydrocele denotes a pathological accumulation of serous fluid in a bodily cavity. A hydrocele testis is the accumulation of fluids around a testicle, and is fairly common. It may be treated surgically. It can occur in infants undergoing peritoneal dialy...
On May 14, 1796, Edward Jenner, an English physician, inoculated James Phipps, age 8, with material from a cowpox lesion on the hand of a milkmaid. Jenner subsequently demonstrated that the child was protected against smallpox. This procedure became known as vaccination, which resulted in the global eradication of smal...
Premature birth overview # Overview Premature birth (also known as preterm birth) is the birth of a baby before the standard period of pregnancy is completed. In most systems of human pregnancy, prematurity is considered to occur when the baby is born sooner than 37 weeks after the beginning of the last menstrual peri...
Cardiac amyloidosis overview # Overview Cardiac amyloidosis is a well-known progressive condition, which has been reported with varying incidence rates. It refers to extracellular deposition of light chains of some serum proteins, that assume a beta pleated structure. Myocardial involvement results in congestive heart...
Superficial parotid lymph nodes The superficial parotid lymph nodes are a group of lymph nodes anterior to the ear. Their afferent vessels drain the root of the nose, the eyelids, the frontotemporal region, the external acoustic meatus and the tympanic cavity, possibly also the posterior parts of the palate and the flo...
Cryptomonad # Overview The cryptomonads are a small group of flagellates, most of which have chloroplasts. They are common in freshwater, and also occur in marine and brackish habitats. Each cell is around 10-50 μm in size and flattened in shape, with an anterior groove or pocket. At the edge of the pocket there ar...
HLA-A31 HLA-A31 (A31) is an HLA-A serotype. The serotype identifies the more common HLA-A*31 gene products. A31 is a split antigen of the A19 broad antigen serotype group. It is similar to the antigens A29, 30, A32,A33, and A74. A31 is more common in Japan, Siberia and Indigenous Americans. It is also more frequent i...
Erythema nodosum # Overview Erythema nodosum (EN) (red nodules) is an inflammation of the fat cells under the skin (panniculitis). It causes tender, red nodules that are usually seen on both shins. EN is an immunologic response to a variety of different causes. # Historical Perspective - Disease name] was first disco...
Interferon alfa-2a dosage and administration # Dosage And Administration Roferon-A recommended dosing regimens are different for each of the following indications as described below. Note: Parenteral drug products should be inspected visually for particulate matter and discoloration before administration, whenever sol...