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135
a02aa430-9053-4f18-ae5e-f3e6d3880bbe
The most important investigation in the given case to diagnose if the condition is a neoplasm?
JAK-2
EPO level
PaO2
Bone marrow aspiration and biopsy
0a
single
Ans. (a) JAK-2The figure shows increased platelets in smear and increased megakaryocytes in bone marrow. To diagnose this as essential thrombocythemia (neoplasm); JAK-2 mutation analysis should be done.
Pathology
Misc. (W.B.C)
3601e6a4-5888-49f2-9cb6-67b4589a2efb
World diabetes day is celebrated on -
8th may
8th march
14th November
1st december
2c
single
Ans. is 'c' i.e., 14th November* 8th may - world red cross day* 8th march - international womens day* 14th november - world diabetes day* 1st december - world AIDS day
Social & Preventive Medicine
Non-Communicable Diseases
65408e88-2c5d-4a4e-9306-16c386ba94eb
An anesthetic agent with boiling temperature more than 75 C is
Ether
Halothane
Cyclopropane
Methoxyflurane
3d
single
Refer Anesthesiology by Longnecker 2008/777 Boiling point of methoxyflurane is 104,7 degree Celsius whereas other flurrinated anesthetics have boiling point between 50 C and 60 C
Pharmacology
Anesthesia
e12ca8ba-526e-4dd3-93f9-1687b9de87d8
Takayam test is used for?
To know the nature of stain
To know the species
For blood grouping
None of the above
0a
multi
Ans. is 'a' i.e. To know the nature of stain o It is a microchemical test to know the nature of stain.Microchemical tests: These tests are based on property of haem part of hemoglobin to form characteristic coloured crystals.1) Teichmann's haemin crystal test2) Takayama hemochromogen crystal test3) Luminal spray test: ...
Forensic Medicine
Identification - Medicolegal aspects
56346f51-cfe9-4a71-b456-a12e7bacc6bd
Treatment of choice in desmoid tumours is -
Irradiation
Wide excision
Local excision
Local excision following radiation
1b
single
null
Surgery
null
c759e77f-7628-4931-b481-aa497e17c78c
A small Ca2+ binding protein that modifies the activity of many enzymes and other proteins m response to changes in Ca2+ concentration, is known as
Cycline
Calmodulin
Collagen
Kinesin
1b
multi
Calmodulin is a calcium-binding regulatory protein, with a molecular weight of 17,000 daltonsIt can bind with 4 calcium ionsCalcium binding leads to activation of enzymes. It is a pa of various regulatory kinasesRef: DM Vasudevan, 7th edition, page no: 503, 504
Biochemistry
Endocrinology
6e5c4ea0-c0f3-42a6-990a-60e76a6d0d38
Dead space is reduced in tracheostomy by
5-10%
15-20%
20-30%
30 - 50%
3d
single
Airflow resistance of the normal upper airway is substantial, constituting up to 80% of total airway resistance during nose breathing and 50% during mouth breathing.Theoretically, tracheostomy tubes should decrease airflow resistance, but in fact, this does not occur because of the smaller radius (inner diameter 7-8 mm...
Microbiology
All India exam
675fed7f-41d4-48c1-afa6-3d05607ef9b6
S/E of diethyl stilbesterol when used in pregnant woman-
Deep vein thrombosis in pregnant woman
Feminization of external genitalia of male offspring
Infeility and development of vaginal carcinoma in female offspring
Virilization of the external genitalia of female offspring
2c
single
Ans. is 'c' i.e., Infeility and development vaginal carcinoma in female offspring Stilbestrol given to pregnant women Increased risk of vaginal and cervical carcinoma in the female offspring in childhood or early adulthood.
Pharmacology
null
7d317f2e-cfde-4d93-9b4a-8ce29283cc15
ASA -3 is
Comorbidities with minimal limitation
Comorbidities with moderate limitation
Comorbidities which are constant threat to life
No comorbidities
1b
single
ASA grade 3 is when comorbidities are present and make patient symptomatic often.
Anaesthesia
null
c3612ca4-cd68-4f9f-a691-4174b60ccfc9
Lesion not seen in Lepromatous leprosy is:-
Macule
Papule
Nodule
Vesicle
3d
single
Lepromatous leprosy The first clinical manifestations are usually dermal (because early nerve involvement is usually asymptomatic) Leonine facies occur due to diffuse involvement of the facial skin Early symptoms Nasal symptoms of stuffiness, discharge and epistaxis, and oedema of legs and ankles due to increased capil...
Dental
Mycobacterial Infections
8ad2709a-af97-4328-8c8c-e8b6cf6c6ba3
The conversion of optically pure isomer (enantiomer) into a mixture of equal amounts of both dextro and levo forms is called as
Polymerization
Stereoisomerization
Racemization
Fractionation
2c
multi
Depending on the rotation, molecules are called dextrorotatory (+) (d) or levorotatory (-) (l). Thus D-glucose is dextrorotatory but D-fructose is levorotatory. Equimolecular mixture of optical isomers has no net rotation (racemic mixture) or Racemization Ref: Textbook of Biochemistry for Medical Students, 7E (DM Vasud...
Biochemistry
Structure and function of protein
9bb82660-2395-45ab-ac2d-e4c8fb998b92
When a homicide case comes to a doctor, he has to inform police. This comes under which section?
39 Crpc
27 Crpc
174 Crpc
176 Crpc
0a
single
Every person, aware of the Commission of ceain offences shall give information to the nearest Magistrate or police officer.This comes under 39 Crpc section. Examples of such offences are: Offences relating to adulteration of food and drugs, etc Offences affecting life (302, 303, 304 IPC) Offence relating to kidnapping ...
Forensic Medicine
Legal sections
e755fd81-d3f1-467b-bc2c-f9bb3d0b818b
Post-dural puncture headache is typically ?
A result of leakage of blood into the epidural space
Worse when lying down than in sitting position
Bifrontal or occipital
Seen within 4 hours of dural puncture
2c
multi
Ans is 'c' i.e. Bifrontal or occipital Characteristics of post lumbar puncture Headache Cause - There is loss of C.S.F which decreases the brains suppoive cushion so that when a patient is upright there is dilatation and tension placed on brain's anchoring structures and the pain sensitive dural sinuses, resulting in p...
Surgery
null
9c20eba0-1614-4dd2-8654-a1545b4338ce
The glomus tumor invasion of jugular bulb is diagnosed by
Carotid angiography
Veebral venousvenography
X-ray
Jugular venography
3d
single
MRI - gives soft tissue extent of tumor; Magnetic Resonance Angiography (MRA) shows compression of the carotid aery whereas magnetic resonance venography shows invasion of jugular bulb by the tumor.
ENT
null
7793833f-c1dc-4b40-ad8b-972c11ea31e1
Chemically steroids are derivatives of
Cholesterol
Ergosterol
Fatty acids
Perhydrocyclopentanophenantherene
0a
multi
Cholesterol is first acted upon by desmolasw and a 6 carbon unit is cleaved off, forming pregnenoloneProgesterone is the first steroid hormone formed from pregnenoloneProgesterone is fuher conveed in to glucocoicoids, mineralocoicoids and sex steroids Ref: DM Vasudevan, 7th edition, page no: 664, 665
Biochemistry
Endocrinology
23939a47-1320-48f9-8f38-4d76e6fe4376
Toxin production by Corynebacterium diphtheria is due to ?
Chromosomal mutation
Presence of plasmid
Lysogenic conversion
Transformation
2c
single
Ans. is 'c' i.e., Lysogenic conversion o The toxigenicity of the diphtheria bacilli depends on the presence in it of corynephages (tox +). Nontoxigenic strains may be rendered toxigenic by infecting them with beta phage or some other larger phage. This is known as lysogenic conversion or phage conversion.
Microbiology
Corynebacterium
c8ccab30-878e-40c8-9565-970d74f7c503
Azoospermia is seen in which syndrome -
Kartagener syndrome
Young syndrome
Both
None
1b
multi
Young's syndrome, also known as azoospermia sinopulmonary infections, sinusitis-infertility syndrome and Barry-Perkins-Young syndrome, is a rare condition that encompasses a combination of syndromes such as bronchiectasis, rhinosinusitis and reduced fertility. In individuals with this syndrome, the functioning of the l...
Pathology
null
23ee37ae-7506-4536-8090-9e3a7022ba0b
Which is the rarest type of von Willebrand disease?
vWD type 1
vWD type 2A
vWD type 2N
vWD type 3
3d
single
Type III vWD is the rarest type of von Willebrand disease. It result from the inheritance of a mutant vWF gene from both parents. TYPES OF vBD: Condition Defect vWD type 1 Mild to moderate quantitative deficiency of vWF (i.e., about 20-50% of normal levels). vWD type 2A The most common qualitative abnormality of vWF se...
Medicine
Platelet & Coagulation disorders
a4929cc9-1460-4b7e-84f7-d98b1d7c1fd5
chelioscopy is the study of -
Foot prints
Palatal prints
Finger prints
Lip prints
3d
single
Lip prints
Unknown
null
1b045676-aba6-43eb-8670-9c3c4bd60a7a
Anatomical closure of ductus arteriosus occurs at –
Birth
3–4 day
10th day
30th day
2c
single
Circulatory adjustments at birth These are brought about because of a shift from placental dependance for gas exchange in the fetus to pulmonary gas exchange in the neonate. 1) Pulmonary circulation Immediately after birth lungs expand due to the first few breaths of the neonate. This causes a fall in pulmonary vas...
Pediatrics
null
9cac582d-668e-4040-ae2e-f0029f21aef8
Rheumatoid factor is directed against-
IgG
IgD
IgM
IgA
0a
single
harshmohan textbook of pathology *detection of circulating autoantibody called rheumatoid factor against Fc poion of autologous IgG in about 80% of cases
Pathology
General pathology
fe85c253-98e1-4223-96c6-f2898dda42b7
Most sensitive investigation for air embolism is
Decreased tidal volume of CO2
Decreased tidal volume of NO2
Doppler ultrasound
Central Venous Presure
2c
single
C i.e. Doppler Ultrasound
Radiology
null
e8e43a1c-0e44-40d2-b702-31b139d131e1
Under the National Programme for Control of Blindness, the goal is to reduce the prevalence of blindness to a level of -
0.10%
0.31%
0.50%
1%
1b
single
To reduce prevalence of blindness in population from 1.38% to 0.31% by 2000. Ref- Park&;s textbook of Preventive and social medicine 24th edition. .
Social & Preventive Medicine
Non communicable diseases
2d3ef985-9423-4bb2-a814-72f686b3f80d
Conjugate vaccine are available for the prevention of invasive disease caused by all of the following bacteria except:
H. influenzae
Strep pneumoniae
Neisseria meningitidis (Group-C)
Neisseria meningitidis (Group-B)
3d
multi
Ans. (d) Neisseria meningitidis (Group B) Note: Conjugate vaccines are available for: a. Hemophilus influenza B. b. Menigococcal serotypes A, C, Y and W-135. c. Streptococcalpneumoniae(pneumococcus).
Microbiology
null
1d029dc4-b64f-4e73-ada6-c1deccc87a11
Which of the following is not required for conversion of acetyl CoA to palmitate?
ATP
Niacin
NADPH
Biotin
1b
single
The pathway conves acetyl-CoA to palmitate and requires NADPH, ATP, Mn2+, biotin, pantothenic acid, and as cofactors. Ref: Harper 28th edition, chapter 23.
Biochemistry
null
c396af37-6e38-4458-909a-7e01e91f617b
Nutrient artery to Femur is a branch of
Inferior gluteal Artery
1st perforating Branch of profunda femoris artery
2nd perforating Branch of profunda femoris artery
Lateral circumflex femoral artery
2c
single
Femur gets its nutrient artery from 2nd perforating Branch arising from profunda femoris artery.
Anatomy
null
c0410138-e961-4d19-a72d-7206d7b8378e
All are stages of anaesthesia except-
Analgesia
Allodynia
Delirium
Surgical anesthesia
1b
multi
Ans. is 'b' i.e., Allodynia o Stages of anaesthesia are Stage of analgesia ( stage 1), stage of delirium or excitment (stage 2), stage of surgical anesthesia (stage 3) and stage of medullary'- paralysis (stage 4).o Guedel described four stages of ether anesthesia known as Guedel stages.Stages of anaesthesiao GAs cause ...
Anaesthesia
Miscellaneous General Anesthesia
9dee6709-ee80-4c43-8a72-8c7ed477c63a
Kuppuswamy socioeconomic status scale comprises of -
Education, family size and housing
Education, occupation and housing
Income, family size and land holding
Education, occupation and income
3d
single
Kuppuswamy &;s socio-economic status scale education occupation family income per month (refer pgno:690 park 23 rd edition)
Social & Preventive Medicine
Health education & planning
a3da19ac-1e6f-4c7a-9e90-2ed8b303c71a
Early strict toilet training can result in
Nocturnal enuresis
Encopresis
Night terror
Temper tantrauma
1b
single
A condition in which a child resists having bowel movements, causing impacted stool to collect in the colon and rectum and lead to leakage. Common causes of this symptom Encopresis can have causes that aren&;t due to underlying disease. Examples include sneezing, constipation, incontinence due to lack of potty training...
Pediatrics
Growth and development
a78c7831-a623-4742-9165-b892a154a733
A 60 year female present with tender irreducible mass immediately bellow and lateral to the pubic tubercle. plain abdominal x- ray shows intestinal obstruction
Small bowel carcinoma
Adhesions
Strangulated inguinal hernia
Strangulated femoral hernia
3d
multi
null
Surgery
null
9070bbb4-2737-4e7e-9507-0b748683187f
Xray showing air column between soft tissue mass and posterior wall of nasopharynx is suggestive of -
Ethmoidal polyp
Antrochoanal polyp
Nasalmyiasis
None of the above
1b
multi
Ans. is 'b' i.e., Antrochoanal polyp o On xray.antrochoanal polyp appears as a soft tissue density and shows a column of air between the soft tissue mass and posterior wall of nasopharynx.
ENT
Pharynx
e6e1fdc1-6f01-434e-8b2d-3567d97741d7
Salk vaccine is a
Live vaccine
Live attenuated vaccine
Toxoid
Killed vaccine
3d
single
null
Social & Preventive Medicine
null
5b3975fe-ea31-46d6-b56d-037055f01b4b
The daily requirement of Vitamin C is –
40 mg
100 mg
200 mg
500 mg
0a
single
null
Social & Preventive Medicine
null
85688d21-c255-4a14-bc1d-a9cf6a20d632
To which of the following family of chemical mediator of inflammation,the lipoxins belong
Kinin system
Cytokines
Chemokines
Arachidonic acid metabolites
3d
single
ref Robbins 7/e p69 lipoxins are a recent addition to the family of bioactive products generated from arachidonic acid.they have anti inflammatory activity
Anatomy
General anatomy
a8575d7f-8608-49b1-8237-96a6ab3c3bd6
Not present in Sideroblastic anaemia is ?
Microcytic anaemia
Decreased transferrin saturation
Sideroblast cells in blood smear film
Ineffective erythropoesis
1b
single
Ans. is 'b' i.e., Decreased transferrin saturation Sideroblastic anemia Sideroblastic anemia is a type of anemia in which the body has adequate amount of iron but is unable to corporate it into hemoglobin. Pathogensis o The basis defect is a failure to completely form heme molecules, whose biosynthesis takes place paly...
Pathology
null
9f7047ce-7627-4620-844a-400a258f17c0
Which of the following tests can differentiate MRKH from testicular feminizing syndrome
3D USG
MRI
Karyotyping
Serum testosterone levels.
2c
single
Karyotyping is best to differentiate between MRKH and testicular feminization syndrome.
Gynaecology & Obstetrics
null
508eeccc-697a-4759-aa03-0572166f30b7
The posterior urethra is best visualized by ?
Static cystogram
Retrograde urethrogram
Voiding cystogram
CT cystogram
2c
single
Voiding cystourethrography is the best method to visualize posterior urethra. Remember, Urethra can be imaged radiographically in two ways. Anterograde techniques --> Best for visualization of posterior urethra. (This is done along with voiding cystourethrography or with voiding following excretory urography) Retrograd...
Surgery
All India exam
318f4f82-6a2e-419d-9f65-a63c36a4b346
Total body iodine is about –
20 mg
30 mg
40 mg
50 mg
3d
single
null
Social & Preventive Medicine
null
6d349161-54d4-4332-b74c-1ed5b72173a3
Which nerve is damaged in fracture surgical neck humerus -
Axillary
Radial
Ulnar
Median
0a
single
Ans. is 'a' i.e., Axillary Complications of fracture surgical neck humeruso Shoulder stiffness.o Axillary nerve is particularly vulnerable, both from the injury and from surgeryo Axillary artery injury o Malunion o Nonunion o Myositis ossificans
Orthopaedics
Fracture of the Humerus
a1a358e5-39f9-49b0-bf22-4770f726d40a
A herd immunity of over - % is considered necessary to prevent epidemic spread of diphtheria-
50%
55%
60%
70%
3d
single
Ans. is 'd' i.e., 70% o A herd immunity of over 70% is considered necessary to prevent epidemic spread, but some believe that the critical level may be as high as 90%.Diphtheriao Diphtheria is an acute infectious disease caused by toxigenic strains of corynebacterium diphtheriae.o Source of infection - cases or carrier...
Social & Preventive Medicine
Communicable Diseases
bf1f425b-d7e1-4ccf-98db-cc0fdd8237b2
Drug of choice for schizophrenic patient with poor oral absorption is?
Haloperidol
Fluphenazine
Clozapine
Olanzapine
2c
single
Clozapine REF: Kaplan and sadock's synopsis in psychiatry 10th ed p. 489-490 Antipsychotics can be categorized into two main groups: the older conventional antipsychotics, which have also been called first-generation antipsychotics or dopamine receptor antagonists (DRA), and the newer drugs, which have been called seco...
Psychiatry
null
e2a08164-9683-4e7e-b860-771e1e6cda66
Most common infections after splenectomy are
Capsulated bacteria
Uncapsulated bacteria
Gram positive sepsis
Gram negative bacteria
0a
single
Oppounist post-splenectomy infection is caused by capsulated bacteria.Post-splenectomy septicaemia may result from Streptococcus pneumoniae, Neisseria meningitides, Haemophilus influenzae and Escherichia coli.Bailey and love 26th edition pg: 1096
Surgery
G.I.T
f47a9c8e-38a5-456b-a8a4-8ebc5a4c8de1
Type of inheritance in MELAS -
AD
AR
Mitochondrial
X-linked
2c
single
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes - abbreted to MELAS - is one of the family of mitochondrial cytopathies, which also include MERRF, and Leber's hereditary optic neuropathy. It was first characterized under this name in 1984. A feature of these diseases is that they are caused b...
Pathology
General pathology
afca78f1-5c3b-4500-9aa8-19b5a988db11
During bilateral adrenalectomy, intra-operative dose of hydrocoisone should be given after:
Opening the abdomen
Ligation of left adrenal vein
Ligation of right adrenal vein
Excision of both adrenal glands
3d
multi
Patients undergoing surgical treatment of endogenous hypercoisolism require glucocoicoid replacement. Steroids are not given pre-operatively because these patients are already hypercoisolemic. Instead hydrocoisone 100 mg IV is given after the removal of second hyperplastic adrenal gland.
Surgery
Parathyroid and adrenal glands
519babb3-7d4b-4387-9173-130244cf5f7f
Which of the following tumors is characterized histologically by pseudopalisading, necrosis, endoneural proliferation, hypercellularity, and atypical nuclei?
Schwannoma
Medulloblastoma
Oligodendroglioma
Glioblastoma multiforme
3d
multi
The features listed in the question are characteristic of a glioblastoma multiforme. Astrocytomas, the most common primary brain tumors in adults, range from low-grade to very high-grade (glioblastoma multiforme). These grades of astrocytomas include grade I (the least aggressive and histologically difficult to differe...
Pathology
Nervous system
b23cb368-34ab-4441-b125-186e0b213d25
Spiral ganglion innervates which cells in the following diagram
A
B
C
D
0a
single
Ans. (a) A(Ref: Ganong, 25th ed/p.202)Spiral ganglionContains cell bodies of the auditory nerve whose peripheral axons innervate hair cells on the organ of Corti90% to 95% of these sensory neurons innervate the inner hair cells (point A)Only 5-10% innervate the more numerous outer hair cells
Physiology
Nervous System
c5634663-0a07-470b-a5e1-4022ad8fd119
A 30 year old male presented with pain in lower extremities, aggravated by walking. He gives the history of cigarette smoking. In this patient prevalence of which histocompatibility antigen is increased?
HLA-B5
HLA-B8
HLA-DR2
HLA-DR3
0a
single
The history suggests that the patient is suffering from Buerger disease. There is increased prevalence of HLA-A9 and HLA-B5 in these patients. HLA DISEASE HLA-B8 Myasthenia gravis, Graves Disease HLA-DR2 Narcolepsy HLA-DR3 Myasthenia gravis, Celiac sprue HLA-DR4/DW4 Rheumatoid ahritis
Surgery
null
e7676b9b-385d-410a-b0d7-e19d90550d7d
Marker of glomus tumor -
CD-57
Cytokeratin
S-100
CD-34
3d
single
Additional studies using immunohistochemical techniques revealed that malignant glomus tumors are characterized by the presence of MIB-1, p53, Bcl-2, and CD34. Up to 4% of the tumors are functional and produce clinically significant levels of catecholamines, norepinephrine, or dopamine with symptoms mimicking a pheochr...
Pathology
miscellaneous
5fcc2d7e-dc12-40ea-98f1-cabf9dfcea7b
A patient has small, oval multiple ulcers in oral cavity with red erythematous margins. The diagnosis is:
Carcinoma
Tubercular ulcer
Aphthous ulcer
Syphilitic ulcer
2c
multi
Aphthous ulcer Small and oval multiple ulcers in oral cavity Has red erythematous margins Syphilitic ulcer Firm, painless, non-itchy skin ulceration Tubercular ulcer Firm, nontender erythematous nodules that soften, ulcerate, and form sinuses.
Surgery
Oral cavity
0a2fdc07-eba6-4ee3-bf1f-9abedf312506
Absolute contraindication for IUCD are all except
Pregnancy
Undiagnosed vaginal bleeding
Pelvic inflammatory disease
Uterine malformation
3d
multi
Absolute contraindications Suspected pregnancy Undiagnosed vaginal bleeding Cancer cervix Previous ectopic pregnancy Relative contraindications Distoions of the uterine cavity due to Congenital malformations Fibroids Anaemia Menorrhagia Reference : Park&;s textbook of preventive and social medicine, 23rd edition, Page ...
Social & Preventive Medicine
Demography and family planning
c0315b82-a9be-498e-8995-008c2c59d508
Rape is defined under: September 2010
IPC 375
IPC 376
IPC 377
IPC 378
0a
single
Ans. A: IPC-375 IPC-375 defines rape. A man is said to commit "rape" who, except in the case hereinafter excepted, has sexual intercourse with a woman under circumstances falling under any of the six following descriptions: ? First: - Against her will. Secondly: - Without her consent. Thirdly: - With her consent, when ...
Forensic Medicine
null
317bdb8f-cb7a-4033-bd95-028a30b6bb0b
Which of the following is the most common presenting symptom of non-cirrhotic portal hypertension ?
Chronic liver failure
Ascites
Upper gastrointestinal bleeding
Encephalopathy
2c
single
null
Medicine
null
02f85815-c2d9-40a3-82a7-bd1d8e9ab556
Least common cause of ambiguous genitalia in female genotype:
21 hydroxylase deficiency
11 hydroxylase deficiency
Fetal steroid sulphatase deficiency
WT1 gene
2c
single
Ans. C. Fetal steroid sulphatase deficiencyRef: Sperojf, 9th/ed, pll9ExplanationPlacental sulfatase deficiency# There is an X-linked metabolic disease characterized by a placental sulfatase deficiency in the syncytiotrophoblast, and postnatally, ichthyosis, occurring in about 1 in 2000-3000 newborn males.# Patients wit...
Gynaecology & Obstetrics
Sex Intersexuality
9502bc3d-5d29-46ba-bbd2-4660be9eed1f
Most common malignancy found in Marjolins ulcer is -
BCC
SCC
Malignant fibrous histiocytoma
Malignant melanoma
1b
single
Ans. is 'b' i.e., SCC o Malignancy arising in burn scar is k-'a Marjolin s ulcer. It is most commonly squamous cell ca, although basal cell carcinoma may also be seen.
Surgery
Miscellaneous (Neoplasia)
2d4f3259-c591-4b5d-8c05-b8739d580587
Babloo a 10-year-old boy presents with # of the humerus. X-ray reveals a lytic lesion at the upper end. Likely condition is
Unicameral bone cyst
Osteosarcoma
Osteoclastoma
Aneurysmal bone cyst
0a
single
Here, two options are there which are included in the differential diagnosis of the lytic lesion in the proximal humerus, i.e., unicameral bone cyst and aneurysmal bone cyst. We cannot differentiate between two on the basis of information provided in the question. However, the best option here is a unicameral bone cyst...
Orthopaedics
null
85c03ae5-73d8-4f7e-a572-7d0d406e2225
Most common type cancer gallbladder in a patient with gallstones
Adenocarcinoma
squamous carcinoma
Adenosquamous carcinoma
Liposarcoma
0a
multi
The most common cancer in a patient with gallstones is adenocarcinoma(90%).Occasionally squamous cell carcinoma,adenosquamous or carcinoid tumour can occur. Reference: SRB&;s manual of surgery,5th edition, page no.659
Surgery
G.I.T
e809ad07-6ead-481f-94e0-108570f195ab
All are tocolytics except
Ritodrine
Salbutamol
Isoxsuprine
Misoprostol
3d
multi
Misoprostol is indicated in cervical ripening prior to Labour whereas tocolytics inhibit uterine contractions and keep the uterus quiescent. Reference: Textbook of Obstetrics : Sheila Balakrishnan pg. 573,196
Gynaecology & Obstetrics
Abnormal labor
478f8784-73dd-4f46-9337-f0f35cde5ef6
In body pethysmography, a person is asked to expire against a closed glottis. What will be the change in the pressure in the lung and the box
Increase in both
Decrease n both
Increase in lung decrease in box
Decrease in lung increase in box
2c
multi
null
Physiology
null
05ab7dd3-4570-478c-a33e-77d3078e05ff
Frey's Syndrome is due to injury of which of the following nerve branch
Facial Nerve
Trigeminal nerve
Glossopharyngeal nerve
Vagus nerve
1b
single
* Auriculo temporal nerve is the Post ganglionic parasympathetic nerve which on injury during parotidectomy, results in Gustatory sweating syndrome known as Frey's syndrome after 2-3 months. * Auriculotemporal nerve is the branch of Mandibular division of Trigeminal Nerve( 5th Cranial Nerve) Ref:- Surgery Sixer 3rd Edi...
Surgery
Head and neck
54fec56d-c7a7-44a1-babe-2da9f8cd84fd
Treatment of choice for carcinoma of lip of lessthan 1 cm is -
Radiation
Chemotherapy
Excision
Radiation and Chemotherapy
2c
single
null
Surgery
null
029017e9-a336-4b9a-bb6e-cb45a7153fd5
Which of the following is not a teiary amine
Atropine
Hyoscine
Glycopyrolate
Physostigmine
2c
single
Refer kDT 7/e p 108,113 The structure of teiary and quaternary amine is depicted in the picture As seen in the diagram, quaternary amine are ionized and thus water soluble. These drugs are not able to cross the blood brain barrier Atropine hyoscine and physostigmine are teiary amines (and thus lipid soluble) and can cr...
Pharmacology
Autonomic nervous system
f8f0f856-65d7-40e1-8363-90dcc8e391c5
Onset of LH surge precedes ovulation by:
12 hours
24 hours
36 hours
48 hours
2c
single
LH surge 36 hrs (24- 36 hrs) before ovulation. LH peak 12 hrs before ovulation.
Gynaecology & Obstetrics
Normal Menstruation, Abnormal Menstruation, Menopausal Physiology and forsight of conception
54bdae92-1c11-40a3-a4d0-b8881d3ad372
Rave drug is ?
Cannabis
Cocaine
Heroin
Ecstasy
3d
single
Rave drugs are ectasy (MDMA), gamma-hydroxybutyrate and rohypnol.
Forensic Medicine
null
67f82c76-9223-4a75-b1ea-7daccca87f5c
Which of the following is present in Paneth cells?
Zinc
Copper
Molybdenum
Selenium
0a
single
Paneth cells, located in the basal poion of the intestinal crypts below the stem cells, are exocrine cells with large, eosinophilic secretory granules in their apical cytoplasm. The granules contain the bactericidal enzyme lysozyme, an arginine-rich protein, and zinc. Paneth cell granules undergo exocytosis to release ...
Pathology
null
8e53c9e0-52bc-47f1-87fe-f7f91153f220
The following features are hallmarks of postprimary pulmonary tuberculosis except-
It results from endogenous reactivation of latent infection
The disease is usually localized to the anterior segment of the upper lobe
If cavity formation occurs, satellite lesions result from the discharge of liquefied contents into the airways
Up to one-third of untreated patients die due to severe pulmonary TB within a few weeks or months after onset
1b
multi
Tuberculosis is classified as one of the granulomatous inflammatory diseases. Macrophages, T lymphocytes, B lymphocytes, and fibroblasts aggregate to form granulomas, with lymphocytes surrounding the infected macrophages. When other macrophages attack the infected macrophage, they fuse together to form a giant multinuc...
Medicine
Infection
194db215-38f0-4aa7-8759-e3fcd51be4df
Greatest portion of teeth is formed by:
Enamel
Dentin
Pulp
Cementum
1b
single
null
Dental
null
12d727f8-8af7-419b-b7b0-87776e00b907
The virus causing which of the following disease produces both intranuclear and intracytoplasmic inclusion bodies ?
Chickenpox
Rabies
Small pox
Measles
3d
multi
Cytopathic effect consist of multinucleate syncytium formation with numerous acidophilic nuclear and cytoplasmic inclusions REF:ANANTHANARYANAN TEXTBOOK OF MICROBIOLOGY 9EDITION PGNO.512
Microbiology
Virology
5c322b99-bd4e-4a40-8423-884046a4eaf8
Nucleotides serve all of the following roles, EXCEPT:
Monomeric units of nucleic acids
Mediators in cellular signalling
Source of energy
Structural component of membrane
3d
multi
Nucleotide Nucleic acids are polynucleotides CAMP and cGMP are cyclic nucleotides involved in signaling pathways. ATP is the cellular currency of energy Membrane is made up of phospholipids and cholesterol and not nucleotides.
Biochemistry
Nucleotides
d92d8aeb-d542-4f1d-88c4-5b7708c23b29
Which is not a branch of cavernous pa of internal carotid aery?
Cavernous branch
Inferior hypophyseal
Meningeal aery
Ophthalmic aery
3d
single
Internal carotid aery is a terminal branch of common carotid aery. It first runs through the neck (cervical pa), then passes through the petrous bone(petrous pa), then courses through the sinuses(cavernous sinuses)and lastly lies in relation to the brain(cerebral pa). AREA OF DISTRIBUTION Cervical pa of the aery does n...
Anatomy
Head and neck
b01236b8-826e-4280-8bf6-d31a2bc4a62f
Stain for fat, all except:
Oil red O
Sudan black
Sudan III
Congo red
3d
multi
Ans. is 'd' i.e., Congo redo Congo red is not used in lipid staining. It is used in the staining of amyloid protein.Staining for lipidsExamplesStain usedNon nolar linidsUnconjugatedlipidsFatty acidsOil red O, Sudanblack, Sudan III & IVFilipinSchultzCalcium lipaseCholesterolCholesteryl estersMono, di and Tri-glyceridesE...
Pathology
Histo Pathology
afee4256-35a4-4ca1-97a1-328095e8fafd
MC site of injury to the ureter during a hysterectomy is: March 2004
At the pelvic brim
In the ovarian fossa
Site of crossing by the uterine aery
As it enters the bladder
2c
single
Ans. C i.e. Site of crossing by the uterine aery
Gynaecology & Obstetrics
null
a1da8466-2ee2-469a-be81-941b013da585
Keratomalacia is associated with:
Measles
Mumps
Rubella
All
0a
multi
A i.e. Measles Measles and diarrhoea can cause vit A deficiency and thus lead to keratomalacia Q
Ophthalmology
null
e261aba2-677c-4cfc-a4b3-a5df15378f09
Butterfly rash is associated with: September 2006, September 2012
DLE
SLE
Rheumatoid ahritis
Reiter's syndrome
1b
single
Ans. B: SLE Cutaneous LE may be pa of an uncommon disease called systemic lupus erythematosus (SLE). Only a few people with cutaneous LE also have SLE. The most common presentation is with a malar eruption or 'butterfly rash' (red patches across the cheeks). Other skin changes in SLE are photosensitivity (a rash on all...
Skin
null
400c266c-e068-425d-b4bc-6ab601878dd7
A 14 year old girl on exposure to cold has pallor of extremities followed by pain and cyanosis. In later stages of life she is most prone to develop:
SLE
Scleroderma
Rheumatoid Ahritis
Dermatomyositis
1b
multi
Answer is B i.e. (Scleroderma): Pallor of extremities, followed by pain and cyanosis suggests a diagnosis of Reynaud's Phenomenon. Reynaud's phenomenon as the presenting manifestation is most strongly associated with scleroderma or systemic sclerosis. Reynaud's Phenomenon and Scleroderma Reynaud's phenomenon (RP) is th...
Medicine
null
a22908b6-e9ae-4002-9d3a-4e55a10da7ab
Infected gangrene of skin and subcutaneous tissues is ?
Dry gangrene
Wet gangrene
Erysipelas
None of the above
1b
multi
Answer- B. Wet gangreneWet gangene When overlying skin of dry gangrenous tissue is devitalized, bacterial infection is superimposed.More commonly due to venous occlusion then aerial occlusion.
Pathology
null
6c2bcf77-b767-488a-b3ba-5489cd889915
A 6-year-old girl complains of otalgia, fever, and irritability. Physical examination reveals a stiff, bulging, red tympanic membrane. Previous history of ear infections is denied. Clinical response to amoxicillin is maximized on which of the following durations?
1 day
5 days
7 days
10 days
1b
single
Prospective nonrandomized evaluations of treatment duration of acute otitis media reveal no difference in outcome if given over 5-day, 7-day, or 10-day duration. However, 10-day treatment is indicated for children with history of acute otitis media within the preceding month.
Surgery
Miscellaneous
16e3368e-eed2-4b5e-9340-19c1f918c73c
Which of the following fluoroquinolone has broadest spectrum activity against bacteria ?
Ciprofloxacin
Norfloxacin
Trovafloxacin
Nalidixic acid
2c
single
Ans. is'c'i.e., TrovafloxacinFouh generation quinolones/fluoroquinolones have broadest spectrum.These are trovafloxacin, fleroxacin, gemifloxacin, prulifloxacin, sitafloxacin and clinafloxacin.
Pharmacology
null
902e2597-232c-4fc3-8f09-c43a0328f57f
A 28 years old female at term presents with gush of fluid and regular contractions. Prenatal investigations reveals Rh negative, antibody negative, husband- Rh positive homozygous. After 10 hours her labor progresses and delivered 3600g baby via normal vaginal delivery. Placenta did not separate spontaneously and manua...
RhoGAM
Indirect Coomb's test
Direct Coomb's test
Detection of fetal cells in maternal circulation
2c
multi
Answer: c) Direct Coomb's testRh NEGATIVE PREGNANCYINVESTIGATION OF Rh NEGATIVE MOTHERSI-Husband's blood grouping & Rh typing.II-Obstetric History: If the woman is primi, it is unlikely for the baby to be affectedIII-Antibody detection: In all cases of Rh negativity, albumin antibody is detected by indirect Coomb's tes...
Gynaecology & Obstetrics
Miscellaneous (Gynae)
3545e511-9b9d-46de-b547-b54e2fdeb4d6
RPGN(rapidly progressive glomerulonephritis) caused by-
FSGS
Wegener's granulomatosis
Good pasteur's syndrome
PAN
1b
single
Granulomatosis With Polyangiitis Previously called Wegener granulomatosis, granulomatosis with polyangiitis (GPA) is a necrotizing vasculitis characterized by a triad of the following: * Necrotizing granulomas of the upper-respiratory tract (ear, nose, sinuses, throat) or the lower-respiratory-tract (lung) or both * Ne...
Pathology
Urinary tract
5c89a7cb-941c-49a8-83c4-869d439990b9
True about nutritional rickets -a) Craniotabesb) Multiple #c) Widening of wristd) ↓ Phosphate in serume) Growth retardation
acde
bde
abcd
abde
0a
multi
Craniotabes, widening of wrist and growth retardation occur in rickets. Serum phosphate is low.
Orthopaedics
null
e11ddd16-6652-467a-81fb-9fd8cb524d28
Vitamin K dependent clotting factors include all EXCEPT
Factor VII
Factor VIII
Prothrombin
Facor IX
1b
multi
VITAMIN K DEPENDENT CLOTTING FACTORS ARE: Factor II (Prothrombin) Factor VII (Proconvertin/Stable factor) Factor IX (Christmas factor/ Antihemophilic Factor B) Factor X (Stuart Prower factor) Protein C Protein S NOTE' Clotting factors inhibited by Antithrombin III are: Factor IX, X, XI & XII
Physiology
null
efe2f87f-7a75-47eb-bc5e-971e7d713bb7
All are true about nitrous oxide except ?
Laughing gas
Causes megaloblastic anemia
Causes diffusion hypoxia
Good muscle relaxant
3d
multi
Ans. is 'd' i.e., Good muscle relaxant Nitrous oxide N,O It is also called laughing gas. It has good analgesic but poor muscle relaxant activity. Second gas effect and diffusion hypoxia occur with N20 only. N20 is the only anaesthetic repoed to produce hematologic toxicity and neurotoxicity with long term administratio...
Pharmacology
null
eedbe06d-a860-4076-9c48-784698083220
A young adult shows non-fluctuant, tender and red swellingin the marginal gingival lesion. This is most likely:
Periodontal abscess
Periapical abscess
Gingival abscess
Periapical sinus
2c
single
null
Dental
null
9e461fcb-281d-49fe-8dfe-2704b999fdc1
Right eye superotemporal quadrantopia, left eye centrocaecal scotoma with headache. Site of lesion is:
Left optic nerve + chiasma
Left optic tract + chiasma
Right optic nerve + chiasma
Right optic tract + chiasma
0a
single
Ans. (a) Left optic nerve + chiasmaRef: Kanski 7/e, p. 826-827This type of field defect is seen in meningiomas where the lesion is at the junction of optic nerve and the chiasma. This is called "junctional scotoma of Traquair". (VFD No. 3-Text)
Ophthalmology
Neuro-Ophthalmology
a41910e6-e32d-4780-b42d-bdbf671d39ba
Viroids are ?
ssRNA
DNA from matric proteins
Naked pathogenic human viruses
Fragments of viruses
0a
single
Genome much smaller than those of known virus. Agent is a protien free low molecular wt RNA REF:ANANTHANARYANAN TEXT BOOK OF MICROBIOLOGY 9EDITION PDNO.442
Microbiology
Virology
fd7d154c-dc3a-437b-a859-d475590559a0
Treatment for fibrous dysplasia in a young 25 yrs old patient involving maxilla is best treated by
Enbloc resection
Cosmetic contouring
Maxillary resection
Radiation therapy
1b
single
null
Surgery
null
b94466f6-ede9-4172-bc8c-1b2cb5ce13c9
Anticholinesterases are effective against all, except :
Cobra bite.
Postoperative ileus.
Carbamate poisoning.
Belladona poisoning.
2c
multi
null
Pharmacology
null
92c4e03e-f5c3-4384-9f63-d2e62b7234e3
A 25 years female was found in the room with 100% burns on her body. The tongue was protruding out; the body was in pugilistic attitude with heat ruptures, peeling of skin, and heat haematoma and heat fractures of the skull. Carboxyhemoglobin was 25% and soot particles were present in the trachea. Which of the combinat...
Heat haematoma & heat ruptures
Heat fracture of skull and peeling of skin
Heat haematoma and pugilistic attitude
Carboxy hemoglobin (25%) and soot particles in trachea
3d
single
Presence of carbon particles (soot) in respiratory passages and elevated level of carboxy-hemoglobin confirms that victim was alive when the burn occurred. i.e. Ante-mortem burn.
Forensic Medicine
null
d107bbd6-532b-4aee-9ba5-f139542feb2a
Altered perception of real objects is
Illusion
Delusion
Hallucination
Delirium
0a
multi
Illusion: A misinterpretation of stimuli arising from an external object(s). Hallucination: A perception that occurs in the absence of a stimulus. Delusion: A false, unshakable belief which is not amenable to reasoning, and is not in keeping with the patient's socio-cultural and educational background. Delirium: it is ...
Psychiatry
Symptoms and signs in psychiatry and classification
02c3fd63-d433-49f5-b688-ad11479d4474
Q. Initial Antihypeensive agent of choice in a patient with stable ischemic hea disease is
Beta-Blockers
Alpha-Blockers
Calcium Channel Blockers
Ace Inhibitors
0a
single
Answer is A (Beta-Blockers) Beta Blockers are recommended as First Line Agents of choice for treatment of hypeension in hypeensive patients with Stable Ischemic Hea Disease.
Medicine
null
e5259d5c-840a-4fc6-a55d-638184739cf8
A 20-year-old man fell from the parallel bar during the Olympic trial. A neurologic examination reveals that he has a lesion of the lateral cord of the brachial plexus. Which of the following muscles is most likely weakened by this injury?,
Subscapularis
Teres major
Latissimus dorsi
Pectoralis major
3d
multi
The pectoralis major is innervated by the lateral and medial pectoral nerves originating from the lateral and medial cords of the brachial plexus, respectively. The subscapularis, teres major, latissimus dorsi, and teres minor muscles are innervated by nerves originating from the posterior cord of the brachial plexus.
Anatomy
Nerve supply, Nerve Lesions
865f66bc-5c5f-4568-9d69-2c8d205d83c0
False about ropivacaine
Less cardiotoxic than bupivacaine
More cardiotoxic than lignocaine
Contains only R enantiomer
Onset of action is faster than bupivacaine
3d
multi
Ropivacaine contains only S enantiomer so cardiotoxicity is less than bupivacaine (but still higher than lignocaine). Anaesthetic propeies (onset, intensity; duration of I action) of ropivacaine are almost similar to bupivacaine.
Anaesthesia
All India exam
a86f69ef-f5c5-4209-8c84-d9f7dee9b07c
After which of the following gestational age is a dead baby said to be a still born ?
20 days
28 days
20 weeks
28 weeks
3d
single
The term stillborn refers to the death of a fetus after 28 weeks of gestation or death of a fetus weighing 1000gms.
Gynaecology & Obstetrics
null
baf8ee99-fa5b-4e72-aa73-1e2030575de4
Normal daily faecal fat excretion:
0-5 gm
5-10 gm
10-15gm
15-20gm
0a
single
Fats excretion less than 7 gm per day in feces is considered normal. More than this amount in feces indicates malabsorption; more than 8 gm/day in feces is called steatorrhea
Physiology
Gastrointestinal System
4c3c6360-6a69-4f9c-9faa-9d6c0ea9481f
Forceps are preferred over vacuum for the delivery because of the following, reasons except?
Vacuum requires more clinical skills than forceps
Vacuum is preferred more than forceps in HIV patient
Forceps are more commonly associated with fetal facial injury
Vacuum has more chance of formation of cephalhematoma
0a
multi
Ans. a. Vacuum requires more clinical skills than forceps (Ref: Dutta 7/e p579, 581)Forceps requires more clinical skills than forceps vacuum.Advantages of Ventouse:It is comfortable and has lower rates of maternal trauma and genital tract lacerationsReduced maternal pelvic floor injuries and is advocated as the instru...
Unknown
null
6773ca12-2ba7-4409-bd60-6e64b43908b3
Normal pressure in superficial venous system of leg while walking is
80 mmHg
60 mmHg
50 mmHg
30 mmHg
3d
single
Pressure in superficial venous system decreases to 30 mmHg while walking as blood flows from superficial to deep veins.
Surgery
null
e12b1526-7f58-4081-9203-c64569dc2a18
Warfarin therapy is prolonged by all except:
Rifampicin
Amoxicillin
Erythromycin
Tetracycline
0a
multi
Barbiturates (but not benzodiazepines), carbamazepine, rifampicin and griseofulvin induce the metabolism of warfarin.The dose of anticoagulant determined during therapy with these drugs would be higher: if the same is continued after withdrawing the inducer- marked hypoprothrombinemia can occur causing fatal bleeding. ...
Pharmacology
null
baf7a6c5-1cc1-44f5-9ba0-60f510fac8d2
Commando operation describes
Maxillectomy, Neck Dissection, Omohyoid muscle removal
Mandibulectomy, Neck Dissection, Omohyoid muscle removal
Mandibulectomy, Neck dissection, Oropharyngeal resection
Ombined maxillectomy and mandibulectomy
2c
single
null
ENT
null
c78bbe53-ef9e-4a96-85af-8738fa43e181
Gamma efferent system is involved in
Tendon reflex
Clonus
Muscle tone
All of the above
3d
multi
(D) All of the above # Motor neurons of y efferent system are regulated to a large degree by descending tracts from a number of areas in the brain.> Golgi tendon organs, are stimulated by both passive stretch and active contraction of the muscle.> The muscles are generally hypotonic when the rate of y efferent discharg...
Physiology
Nervous System
e332a855-7f8b-4aa9-82b9-66a6c4a2dc6f
In takayasu aeritis there is
Loss of pulses
Renal hypeension
Coronary aneurysm or its dilation
All of the above
3d
multi
Takayasu aeritis affects the aoa, its major branches and occasionally the pulmonary aeries. The typical age at onset is 25-30 years, with an 8 : 1 female-to-male ratio. It has a worldwide distribution but is most common in Asia. Takayasu aeritis is characterised by granulomatous inflammation of the vessel wall, leading...
Medicine
Immune system