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135
055fc135-e603-4705-8665-dfdb50c133ce
A 5-year-old girl came with history of progressively increasing pallor since bih and hepatosplenomegaly. Which is the most relevant test for achieving diagnosis?
Hb electrophoresis
Peripheral smear examination
Osmo c fragility test
Bone marrow examination
0a
multi
Progressive increasing pallor along with hepatosplenomegaly in a five-year-old girl is consistent with a diagnosis of thalassemia. (Thalassemia intermedia) 'Hemoglobin electrophoresis' is the test of choice of diagnosing this condition and hence is the option of choice here.
Physiology
All India exam
591077e8-d0f6-4b9c-a74a-4e2ad01eadda
Creatine is made up of all, except -
Glycine
Alanine
Methionine
Arginine
1b
multi
Ans. is 'b' i.e., Alanine o Creatine and creatinine are not amino acids, but specialized products of amino acids. Creatine is synthesized from glycine, arginine and methionine. Synthesis start with formation of guanidoacetate from glycine and arginine in kidney. Further reactions takes place in liver and muscle.Thus, b...
Biochemistry
Miscellaneous (Structure & Function of Proteins)
415f223c-c54c-4ee0-87bd-4dbcefe19c8e
which of the following class antidepressent used in the management of smoking sessation
SSRI
MAOI
NDRI
RIMA
2c
single
NDRI * IMPOANCE Anti-depressant which does not deal with serotonin neurotransmission Also called as Zyban * MECHANISM Prevents reuptake of nor adrenaline and dopamine * DRUGS Bupropion * USE ADHD SMOKING CESSATION HYPOACTIVE SEXUAL DESIRE DISORDER * SIDE EFFECTS seizures Ref. kaplon and sadock, synopsis of psychiatry, ...
Psychiatry
Pharmacotherapy in psychiatry
b2d73430-2b7d-4807-844f-10beab7ab25c
False statement about bilirubin is
Bilirubin circulating in plasma by covalently binding with albumin
Bilirubin is taken up across the sinusoidal (basolateral) membrane of hepatocytes by a carrier-mediated mechanism
Conjugated bilirubin in plasma undergoes stool elimination
Conjugated bilirubin is then directed primarily toward the canalicular (apical) membrane
2c
multi
Bilirubin transpo: Bilirubin circulates in plasma noncovalently, bound to albumin. It is taken up across the sinusoidal membrane of hepatocytes by a carrier-mediated mechanism. Bilirubin uptake is mediated by a liver-specific sinusoidal organic anion transpo protein, (OATP1B1, SLC21A6) Then bilirubin is directed by cyt...
Medicine
null
d775a7a2-af6d-4bdc-8d1e-54f4badf00e8
The cause of death in cyanide poisoning is
Anoxic anoxia
Anaemic anoxia
Histotoxic anoxia
Stagnant anoxia
2c
single
Anoxic anoxia: caused by a complete lack of oxygen to the brain. It occurs when a person is in an environment without enough oxygen, such as at high altitudes.Anemic anoxia: Anoxia due to anemia is not severe at rest unless hemoglobin deficiency is marked. However anemic patients may have considerable difficulty during...
Physiology
Respiratory system
c8f9e3a0-cfaa-4b68-9fa7-3b7dfe1b7a94
Which of the following chromosomal abnormalities is most likely to cause mental retardation?
Klinefelter's syndrome
Fusion of chromosomes 21 and 15
Turner's syndrome
Trisomy 21
3d
single
Ans. D. Trisomy 21An extra chromosome 21 is the most common genetic abnormality found in Down syndrome, and the abnormality most likely to cause mental retardation. Abnormalities in autosomal chromosomes are, in general, associated with mental retardation. The chromosomal aberration represented by 46 chromosomes with f...
Psychiatry
Child Psychiatry
515cc7ea-4713-46a5-8062-4210b9aeef57
Which pa of subclan aery is affected by stenosis is:
First pa
Second pa
Third pa
All pas are equally affected
0a
multi
Most common etiology of subclan stenosis is atherosclerosis, and it mostly affects the ostium or proximal pa of subclan aery. Ref: Peripheral and Cerebrovascular Intervention By Deepak L. Bhatt, Page 102
Surgery
null
d7255879-305b-4051-ad48-1fbd79a666cd
Valley fever or desse rheumatism is caused by
Coccidioides
Cladosporium
Phialophora
Histoplasma
0a
multi
Coccidioides causes primary pulmonary disease which can be mild influenza-like fever ( valley fever) to severe pneumonia. Ref: Textbook of Microbiology, Ananthanarayan and Paniker; 9th edition
Microbiology
mycology
7265c51b-9dc7-4b93-b97b-4974ba8f4973
Ductus arteriosus obliterates to form:
Ligamentum venosum
Ligamentum teres
Ligamentum hepatis
Ligamentum arteriosum
3d
single
Ans. D. Ligamentum arteriosumChanges in Fetal Circulation Just after Birth After birth, the placenta is separated from newborn and lung startsoxygenating the blood, i.e., respiration is established. Now the oxygenated blood comes to heart from the lungs. As a result, the following changes take place in fetal circulatio...
Anatomy
Embryology
a5b9b119-bf29-4b03-9673-6ade4489dbf4
What is the likely source of infection for Pus from sphenoethmoidal recess?
Sphenoid sinus
Ethmoidal sinus
Maxillary sinus
Frontal sinus
0a
single
Ans: (a) Sphenoid sinusRef: Dhingra's ENT 6th ed. /138* Spheno ethmoidal recess is situmated above the superior turbine. Sphenoid sinus opens into is* Sphenoid sinus. It has an anterior part & posterior part.Anterior Part: roof related to the olfactory tract, optic chiasma, frontal lobe while the lateral wall is relate...
ENT
Paranasal Sinuses
5d1e77c5-3bd1-45a2-a784-3ad9d4db8a9a
The above nail changes are seen in:
Lichen planus
Alopecia areata
Psoriasis
Onycholysis
2c
multi
Salmon patch or translucent oil drop like discoloration beneath nail plate is calssically seen in Psoraisis.
Dental
null
b1ed28c9-87c0-4759-942d-919cfd83f045
Resource person for Training ofASHA are
AWW and MPW
AWW and ANM
MPW and ANM
ANM and MO
1b
single
Ans. is 'b i.e., AWW and ANM o Angan-Wadi Workers (AWW) and Auxiliary Nurse Midwife (ANM) act as resource persons far training of ASHA (Accredited Social Health Activist).
Social & Preventive Medicine
null
e591ca22-90d3-4b8e-9730-207ccf0df242
Most common site of tuberculosis of spine is?
Thoracolumbar
Sacral
Cervical
Lumbosacral
0a
single
Ans. (a) ThoracolumbarRef: Apley 387-389, Schwartz's Principles of Surgery 9th ed ch-29 M Tuli 3rded p-192
Orthopaedics
Skeletal Infections
736eb304-cd67-4f89-acf4-91cde8a21911
Advantages of wrought gold alloy clasp wires over cast gold clasps of the same cross sectional area are
Coarser grain
Higher yield strength
Greater flexibility
More accurate adaptation to the tooth
2c
multi
null
Dental
null
b378fd4c-42e8-4169-8b23-d33b6f2b39a4
Angiography is the investigation of choice in:
Posterior vitreous detachment
Rhegmatogenous retinal detachment
Retinoschisis
Central serous retinopathy
3d
single
Ans. Central serous retinopathy
Ophthalmology
null
315f34cb-d069-474b-908d-6f039a07c0f4
Half life of insulin is -
5min
1hr
12hr
24hr
0a
single
Ans. is 'a' i.e., 5 min o The half-life of insulin in the circulation in humans is about 5 min. Insulin binds to insulin receptors, and some is internalized. It is destroyed by proteases in the endosomes formed by the endocytotic process.
Physiology
Endocrinology metabolism
e8afffb4-4c1e-4c26-bc72-767d71a88c4c
Cultivable (in vitro) hepatitis virus is -
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
0a
single
HAV can be grown in some human and simian cell cultures and is the only human hepatitis virus which can be cultivated in vitro. REF:ANANTHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO-541
Microbiology
Virology
3ca27d0a-c2ba-42fd-8119-c72cc8883e41
High inguinal orchiectomy specimen showed teratoma testis with involvement of epididymis; stage is
T 1
T 2
T 3
T 4 b
0a
single
null
Surgery
null
d954191f-e959-4efb-b0d2-62700b5d863f
Development of heart is from which of the following:
Pharyngeal arches
Forebrain
Upper limb
Heart
3d
single
ANS. DThere has been a rising trend of asking embryology images in AIIMS. May session had asked the development of nucleus pulposus (Answer was notochord). Development of cerebral cortexDevelopment of palate and anomalies of it* Midline cleft lip: Due to non-fusion of 2 median nasal process* Harelip (not midline): Due ...
Anatomy
Embryology
7a08e5ae-33f4-4888-86f9-737d2a301947
Which of the following mutations in a tumor suppressor agent causes breast carcinoma
P43
P53
P73
P83
1b
single
Ref Robbins 9/e p294 Mutation in p53 tumor suppressor gene is strongly associated with breast cancer,as well as many other sarcomas and carcinomas .this condition is called li Fraumeni syndrome Li-Fraumeni syndrome is a rare, autosomal dominant, hereditary disorder that pre-disposes carriers to cancer development This ...
Anatomy
General anatomy
7dadbaf6-dac9-4748-805a-c661a159d7b9
Increased permeability in acute inflammation is due to
Histamine
IL-2
TGF-p
FGF
0a
single
Formation of endothelial gaps in venules, i.e. immediate transient response is the most common mechanism causing increased vascular permeability in acute inflammation, Mediators involved in this mechanism are i. Immediate (more important): Histamine, bradykinin, leukotrienes, neuropeptide substance P. ii. Somewhat del...
Pathology
null
bbddee4f-f497-406e-ac27-7ea808c90543
Iodine gives red colour with
Starch
Dextrin
Inulin
Glycogen
3d
single
Amylose: Gives blue with iodine testAmylopectin: Gives reddish violet with iodine testGlycogen: With iodine-: deep red colour
Biochemistry
All India exam
8166eee0-26f2-4582-9e64-78759875e1c4
Essential fatty acid -
Linoleic acid
Palmitoleic acid
Oleic acid
Arachidonic acid
0a
single
Ans. is 'a' i.e., Linoleic acid o The three polyunsaturatedfatty acids (PUFAs), namely, linoleic acidQ linolenic acidQ, and arachidonic acidQ are called essential fatty acids.o They are called essential fatty acids because human beings require these fatty acids but cannot synthesize themQ,o Humans lack the enzymes to i...
Biochemistry
Biosynthesis of Fatty Acids and Eicosanoids
fcc56d00-74ea-4881-aa0f-7a8116bb1ce3
Centrally acting anti hypertensive drug is -
Phenoxybenzamine
Methyl dopa
Propanolol
Prazosin
1b
multi
Ans. is 'b' i.e., Methyl Dopa Centrally Aeting Svmpatholvticso These drugs reduce sympathetic outflow from vesopressor centers in brainstem. Examples are :1 .Clonidine3.Guanabenz5. Rilmenidine2. Methyldopa4. Guanfacine6. MoxonidineClonidineo It acts (partial agonist) on a, receptors, especially a2A in brainstem - Stimu...
Pharmacology
Anti-Hypertensive
72832056-1a34-4afc-b3c0-15ab645866f8
Local anaesthetics act by?
Na channel inhibition inside gate
Na channel inhibition outside gate
K channel inhibition inside gate
K channel inhibition outside gate
0a
single
Ans. is 'a' i.e., Na channel inhibition inside gate Local anesthetics act by inhibiting Na' channels from inside. Mechanism of action of LA Local anaesthetics block generation and conduction of nerve impulse at all pa of neuron where they come in contact, without causing structural damage. Thus not only sensory but mot...
Anaesthesia
null
ac1ed5cb-10a1-443f-9681-fec5b0b07000
APACHE II score involves all except?
GCS
Arterial PH
Mean BP
Serum amylase
3d
multi
Ans. (d) Serum amylaseRef-.Harrison 19th edition, Chapter 267* Acute Physiology and Chronic Health Evaluation II is the most commonly used Severity of illness scoring system in America* Age, type of ICU admission (after elective surgery vs. nonsurgical or after emergency surgery), a chronic health problem score, and 12...
Medicine
C.N.S.
3ab8556a-cfe0-4697-955b-ed8e6ac7025d
Extensive surgical debridement, decompression or amputation may be indicated in the following clinical setting except
Progressive synergistic gangrene
Acute thrombophlebitis
Acute haemolytic streptococcal cellulitis
Acute rhabdomyolysis
1b
multi
Superficial thrombophlebitis management This is a superficial venous thrombosis. An abnormal endothelium is a much more common precipitating factor than in most DVTs. Common causes include external trauma (especially to varicose veins), venepunctures and infusions of hyperosmolar solutions and drugs. The presence of an...
Surgery
Urology
2dfc018a-a08b-442b-b15d-97089cadfd28
Acetyl CoA is used for synthesis of following, except :
Carbohydrates
Ketone bodies
Cholesterol
Non-ketogenic amino acids only
3d
multi
Acetyl-CoA is the third branch point of primary metabolic control, and coordinates carbohydrate, ketone, and fat/lipid pathways.Acetyl-CoA is the product of carbohydrate, protein, and lipid catabolism.Acetyl-CoA is a substrate for the citric acid cycle and can be oxidized to generate energy. It is not used for the synt...
Biochemistry
null
045e8869-370f-448f-ab38-51026b71a102
All of the following are absolute indications for tonsillectomy, except
Recurrent attacks
Peritonsillar abscess
Suspected malignancy
Acute tonsillitis
3d
multi
Recurrent throat infections, peritonsillar abcess, tonsillitis causing febrile seizures, hyperophy of tonsils causing sleep apnoea or speech interference and any suspicion of malignancy are absolute indications for tonsillectomy.
ENT
null
7d79045b-b41e-43a2-a60a-fc716e0146bc
Which of the following is found in secondary granules of neutrophils?
Catalase
Gangliosidase
Proteolytic enzyme
Lactoferrin
3d
single
Neutrophils have two main types of granules The smaller specific (secondary) granules contain lysozyme, collagenase, gelatinase, lactoferrin, plasminogen activator, histaminase, and alkaline phosphatase. The larger azurophil (primary) granules contain myeloperoxidase, bactericidal factors (such as defensins), acid hydro...
Pathology
null
3139ed09-d99e-4d07-9dd4-4e6970ffb50c
Deep peroneal nerve doesn't supply -
Tibialis anterior
Extensor hallucis longus
Extensor digitorum longus
Peroneus brevis
3d
multi
Muscles of anterior compartment of leg are supplied by deep peroneal nerve. Muscles of lateral compartment of leg (Peroneus longus, peroneus brevis) are supplied by superficial peroneal nerve.
Anatomy
null
49f1fecd-7312-4130-b863-bc903b143a14
In carcinoma base of tongue pain is referred to ear through
Trochlea
Olfactory
Glossopharyngeal
Abducent
2c
single
Ans. is 'c' i.e., Glossopharyngeal Referred otalgiao As ear receives nerve supply from Vth (auriculotemporal branch), IXth (tympanic branch) and IXth (auricular branch) cranial nerves; and from C2 (lesser occipital) and C2 and C3 (greater auricular), pain may be referred from these remote areas.Via IXth cranial nerveDe...
Unknown
null
3e5973c2-aeb0-4eb2-af12-f3d0e279d71f
Clinical feature(s) seen in Kwashiorkar is/are _______
Loose wrinkled skin
Hunger pangs
Simian facies
Edema and apathy
3d
single
Kwashiorkar is a form of severe acute malnutrition (SAM) characterized by edema and apathy. Edema is most likely to appear first on the feet and then in the lower legs. It can develop into generalized edema affecting the hands, arms and face. Moon face Skin changes include depigmentation of skin, dermatoses, dark, crac...
Pediatrics
Nutrition
5fa14400-41b8-4ce0-a818-366aa60d0d05
A 25 year old male presented with pigmentation of nose and pinna. After voiding, his urine becomes dark. His spine is most likely to show-
Atlantoaxial subluxation
Spondyloptosis
Basilar invagination
Calcification of disc
3d
single
Ans. is 'd' i.e., Calcification of disc Clinical features of the patient suggests the diagnosis of AlkaptonuriaClinical problems arise from degenerative changes in articular cartilage with the development of ochronotic arthritis and from calcification of intervertebral discsOther clinical features areScleral pigmentati...
Medicine
Immunology and Rheumatology
58e3aad7-3bf0-4c97-91f7-8921f050ee8c
Following is a doctrine related to negligence -
Therapeutic misadventure
Privileged communication
Professional secrecy
All of the above
0a
multi
Ans. is 'a' i.e. Therapeutic misadventureo Diagnostic or Therapeutic misadventure is the occurrence of misadventure causing injury or death of the patient due to inherent risk of procedure or drug, e.g. adverse effects of a drug. It is unintentional.Doctrines related with negligence1) Resp Ipsa Loquitar (fact speaks fo...
Forensic Medicine
Medical Negligence
273c5c46-008c-4682-ba1a-caff1e7f8bd4
On one side kidney is normal, while other side kidney is contracted with scar, what is the most probable diagnosis?
Chronic pyelonephritis
Polycystic kidney
Renal artery stenosis
Tuberculosis of kidney
0a
single
null
Pathology
null
fd13bbce-af48-4b91-a89f-e543ee73ceda
If amphotericin B is administered, the patient should be premedicated with :
Diphenhydramine
Ibuprofen
Prednisone
Any of the above
3d
multi
null
Pharmacology
null
4974b9cf-fd74-44eb-91a2-7f8e757cde99
Cytokine causing fever -
IL-6
IFN-y
IL-18
EL-4
0a
single
Ans. is 'a' i.e., IL-6 Pyrogeneso Pyrogenes are substances that cause fever,o Pyrogens may be exogenous or endogenousExogenous - Bacterial toxinsEndogenous - IL-1, TNF-a, IL-6, Interferons, Ciliory's neurotropic factoro These pyrogenes increase the level of PGE2 in the hypothalamus that elevates the thermoregulatory se...
Pathology
Cellular Pathology
6c1cb10e-322b-4353-8013-8af60bb3496f
Best diagnosed with USG at first trimester
Anencephaly
NT defects
Meningocele
Option not recalled
0a
multi
Ans. A. Anencephaly Ref: DC Dutta's obstetric p408ExplanationIn the first half of pregnancy, the diagnosis of anencephaly is made by elevated alpha-fetoprotein in amniotic fluid and confirmed by sonography.Question not recalled properly: Imerslund-Grasbeck syndrome, its cause was asked.ExplanationCaused by low levels o...
Gynaecology & Obstetrics
Diagnosis in Obstetrics
455b0fb6-8f82-45ec-8b73-18dae822ad64
GFR is increased when -
Plasma oncotic pressure is increased
Glomerular hydrostatic pressure is decreased
Tubular hydrostatic pressure is increased
increased renal blood blow
3d
single
D i.e., Increased renal blood flow
Physiology
null
9ff6b905-2f3e-494e-acd9-29b9f652c918
What is the investigation going on in Ophthalmology examination
Pachymetry
Tonometry
Biometry
LASER interferometry
1b
single
Goldmann Applanation tonometry Gold standard. Based on Imbe Fick law. If cornea is thinner than reading is falsely low. If cornea is thicker, it is falsely high. Applanation tonometry Other Options Pachymetry: Corneal thickness Biometry: Calculation of Power of IOL to be implanted after cataract surgery LASER interfero...
Ophthalmology
Glaucoma
d3e6c147-9f15-47dd-947a-d18672c91161
The most common site of nasopharyngeal carcinoma is
Fossa of Rosenmuller
Palatine tonsils
Antrochoanal region
Valleculae
0a
multi
The commonest site of origin of nasopharyngeal carcinoma is fossa of Rosenmuller in the lateral wall of the nasopharynx. Tumor can spread to the following areas:- Cranium through foramen lacerum & ovale → cranial nerves involvement (III, IV, V, VI); facial pain, and ophthalmic symptoms. Parapharyngeal space → cranial ...
ENT
null
07316690-c74a-4cb6-a150-c7e5ffdffee4
All of them are true about ERG except
Measures the potential difference of the neurosensory layer of retina
The negative A wave is produced by the hyperpolarization of the photoreceptors
The positive B wave is due to the bipolar and Muller's cells
Flash ERG is a good for detection of macular diseases
3d
multi
Electroretinography (ERG) is the record of changes in the resting potential of the eye induced by a flash of light. Components of normal electroretinogram (ERG) a-wave. It is a negative wave possibly arising from the rods and cones (photoreceptors). b-wave. It is a large positive wave which is generated by Muller's cel...
Ophthalmology
Ophthalmology Q Bank
51152600-c7d3-4f9c-8fac-32cd0ba10f44
Contracted socket occurs because of all the following except:
Chronic low grade infection
Chronic mechanical irritation
Irradiation
Loss of fatty tissue during surgery of enucleation
3d
multi
Ans. Loss of fatty tissue during surgery of enucleation
Ophthalmology
null
e4ccb23b-38bb-4fa7-b97b-a64e391f75be
In a population of 100 prevalence of candida glabrata was found to be 80%. If the investigator has to repeat the prevalence with 95% confidence what will the prevalence be
78-82%
72-88%
76-84%
74-86%
1b
single
Confidence Intervals for Population proportions (For 95% Confidence) CI = P + 2 SEP = P + 2 √pq/n Here, P=0.80 (80%); p=0.80; q= 1-p = 1-0.80 = 0.20; n=100 CI = 0.80 + 2 √0.8*0.2/100 = 0.80 + 0.08 = 0.72, 0.88 (72%, 88%)
Social & Preventive Medicine
null
5d303c62-b64a-489d-884b-26244ac98d3d
Trendelenburg test is positive in which of the following condition:
L3 L4 PIVD
L5 S1 PIVD
Synovitis of the hip
Femoroacetabular Impingement Syndrome
1b
single
In L5 S1 PIVD Superior gluteal nerve is effected which supplies the abductors of hip i.e Gluteus medius and minimus causes trendelenburg gait. TRENDELENBURG SIGN Normally when the body weight is suppoed on one limb, the glutei (medius and minimus) of the suppoed side contract and raise the opposite and unsuppoed side o...
Orthopaedics
Pelvis and Hip Injury
0c42b8ac-dd4d-46bf-b973-82b0cba88d0f
Primitive streak develops from?
Mesoderm
Hypoblast
Epiblast
Neural plate
2c
single
Around day 14, the epiblast cells form primitive streak,. Notochord is formed by the mesoderm cells developed by epiblast cells.
Anatomy
JIPMER 2017
032f4678-6fba-431a-8e64-c1e1bed96c2e
Fluid flow in and out of the dentinal tubules is proportional to the tubule diameter by:
Third power of the diameter
Sixth power of the diameter
Square of diameter
Fourth power of diameter
3d
single
Fluid flow in dentin tubules follows Poiseuille’s law as all tubular structures:
Dental
null
ec8c9812-a433-4583-abd0-17ac263f9e1c
Primary closure of incised wounds must be done within:
2 hours
4 hours
6 hours
12 hours
2c
single
WOUNDS CAN BE CLOSED BY Primary suture:   - Clean wounds   - Selected contaminated wounds after thorough wound toileting and debridement Delayed primary suture:  - Heavily contaminated wounds  - Wounds in which wound toileting has been delayed for 6-8 hours Left open to heal by secondary closure
Surgery
null
cd92d5f0-697a-4575-9627-372c780d3e0d
Dose of MgSO4 in asthma is
8 g i.v. over 20 minutes
2g infused over 20 minutes
2g i.v. over 40 minute
6 g i.V. over 40 minutes
1b
single
Bronchodilators Bronchodilator therapy is central to the management of breathlessness. The inhaled route is preferred and a number of different agents delivered by a variety of devices are available. Choice should be informed by patient preference and inhaler assessment. Sho-acting bronchodilators may be used for patie...
Medicine
Respiratory system
1403e13d-49ef-46f5-a09d-5b4e94a1da85
A 10-year-old boy has a fracture of the femur. The biochemical evaluation revealed Hb 11.5 gm/dl and ESR 18 mm 1 hour, serum calcium 12.8 mg/dl, serum phosphorus 2.3 mg/dl, alkaline phosphatase 28 KA units and blood urea 32 mg/dl. Which of the following is the most probable diagnosis in his case?
Nutritional rickets
Renal rickets
Hyperparathyroidism
Skeletal dysplasia
2c
single
null
Medicine
null
b6e6c105-e7aa-4a62-9795-3cedeb34a6d4
Trendelenburg test is positive due to injury to which of the following nerve?
Obturator
Sciatic
Superior Gluteal
Inferior Gluteal
2c
single
Superior Gluteal A positive Trendelenburg is relatively non-specific and may indicate:Pain (e.g. due to osteoahritis of the hip joint)Weak hip abductors (gluteus medius, gluteus minimus)Sho femoral neck/ fracture of neckDislocation or subluxation of the hipNeuropathyGluteus medius and minimus are supplied by Superior G...
Anatomy
null
fbb18cdd-fd65-4e17-a4e5-383606d62b89
True about area specific Curette is
Used in specific areas
Curved in two planes
One cutting edge is used
All of the above
3d
multi
null
Dental
null
dbe45c6e-1d35-4144-bd42-c38a7b729e4a
Nerve supply of opponens pollicis ?
Superficial branch of ulnar nerve
Deep branch of ulnar nerve
Median nerve
Posterior interosseous nerve
2c
single
Hand muscles supplied by median nerve are :- i) Thenar muscles (except adductor pollicis) :- Flexor pollicis brevis, opponens pollicis and abductor pollicis brevis. Adductor pollicis is supplied by ulnar nerve. ii) First two lumbricals. Hand muscles supplied by ulnar nerve are :? 1) Superficial terminal branch : It sup...
Anatomy
null
4da94c06-23ef-48cc-89ff-4d90acd1a09c
A patient presented with splenomegaly, anemia & shows reticulocytosis with increased bone marrow cellularity. The diagnosis is:
Pernicious anemia
Hemolytic anemia
Myelofibrosis
Hairy cell leukemia
1b
single
Hemolytic anemia - reticulocytosis with splenomegaly is seen. Skull and skeletal deformities can occur in childhood due to a marked increase in hematopoiesis and resultant bone marrow expansion
Medicine
Thalassemia
fa303bdd-78b4-401c-bd0c-6eb5761b88fb
Laboratory test of ANUG is:
Complement fixation
Dark field examination
Tissue culture
Animal inoculation
1b
single
null
Dental
null
5253206a-3350-434a-9d8d-182361ab086e
Which is pleuripotent stem cell ?
Embryonic stem cell
Tissue stem cell
Adult stem cell
Hematopoietic stem cell
0a
single
Answer- A. Embryonic stem cellStem cellsEmbryonic stem cells : These are pleuripotent cellsAdutt stem cells
Pathology
null
145c914b-4e49-46a7-950d-5b12e8beb4c6
Which of the following statement is true regarding time of ovulation?
Occurs before LH surge
Occurs after biphasic rise in basal body temperature
Occurs after follicular ripening by FSH
Occurs after disappearance of cervical mucus thickening
2c
multi
Ans. c. Occurs after follicular ripening by FSH (Ref: Williams Obstetrics 23/e p355-356: Ganong 22/e p438: Shaw's 13/e p212)Follicular phase is under control of FSH and LH. Both FSH and LH is responsible for follicular ripening, but a surge in LH secretion triggers ovulation.OvulationLH surge is primarily caused by 'po...
Physiology
Sex Hormones
59afed95-2a68-4532-b556-679715e25a2c
Not true regarding Choledochal cyst
Epigastric mass
Jaundice
Pain in abdomen
Cystojejunostomy is the treatment of choice
3d
multi
Choledochal cyst Cystic dilation of the biliary ducts, more common in females Clinical features. Classical triad : Pain, jaundice (intermittent) & abdominal mass(10%). Most common symptom in infants : Jaundice (in 80%) Most common symptom in patients >2 years of age : Abdominal pain. In children, the major clinical sym...
Anatomy
G.I.T
735f7a0f-5bef-4714-b9ee-e0849a025d03
Maximum contribution to atomospheric air is-
N2
O2
CO2
Helium
0a
single
Ans. is 'a' i.e., N2 * The constituents of air:-# Major - Nitrogen (N2) - 78.1 %, Oxygen (O2) - 20.93%, Carbon dioxide (CO2) - 0.03%# Minor - Argon, neon, krypton, xenon, helium, water vapour, traces fo ammonia, suspended matter (dust, bacteria, spores, vegetable debris).
Social & Preventive Medicine
Environment and Health
5232a258-3e43-481c-b532-093247683875
Ring Enhancing lesion In AIDS patient is Most Likely due to?
Cryptococcosis
Hydatid Cyst
Neurocysticercosis
Toxoplasmosis
3d
single
*Toxoplasmosis and CNS lymphoma are the major differentials for a Ring Enhancing lesion in AIDS Patients Toxoplasmosis produces Eccentric target sign within a ring Enhancing lesion
Radiology
Neuroradiology
eb379b18-9f1c-476e-8bf8-d7379165ce9d
Which group of drugs is most effective for the healing of Non steroidal Anti Inflammatory Drug (NSAID) induced gastric ulcer-
Prostaglandin analogues
H2-receptor antagonists
Proton pump inhibitors
Antacids
2c
single
Ans. is 'c' i.e., Proton pump inhibitors o Drug of choice for NSAIDs induced peptic ulcer ---> PPIs o Most specific drug for NSAIDs induced peptic ulcer --> Prostaglandin analogue.
Pharmacology
null
20d27f25-9a0e-45a3-90cb-770510dd8905
Mature RBC contains all except -
Enzyme of HMP shunt pathway
Enzyme of TCA cycle
Glycoytic enzymes
Pyridine nubleotides
1b
multi
Ans:B .) Enzymes of TCA cycle Erythrocytes (RBC) lack mitochondria (so TCA cycle enzymes) and completely rely on glucose as their metabolic fuel. They metabolize it by anaerobic glycolysis.
Biochemistry
null
4ae73ffd-8a1a-4027-a0f2-53aedcc25fef
A patient developed fixed drug eruptions after taking ceain medications. Which of the following drug will give rise to these skin lesions in this patient?
Phenolphthalein
Aspirin
Dapsone
All of the above
3d
multi
A fixed drug eruption (FDE) is an adverse cutaneous reaction to an ingested drug, characterized by the formation of a solitary (but at times multiple) erythematous patch or plaque. Most commonly implicated agents in fixed drug eruptions: Tetracyclines (tetracycline, minocycline) Sulfonamides, other sulfa drugs Metronid...
Skin
null
62677977-9490-48c1-9bdf-53aeb9c29e52
A woman with amenorrhea is having negative progesterone challenge test but has bleeding on combined estrogen-Progesterone challenge. What can be the cause -
Anovulation
Asherman syndrome
Pregnancy
Pituitary tumor
3d
multi
Ans. is 'd' i.e., Pituitary tumor Negative progesterone challenge test - which rules out PCOD - (otherwise too, PCOD is a cause of secondary amenorrhea).When next step was done i.e., estrogen, progesterone combined test - It comes out to be positive i.e., compament I system (uterus, endometrium and outflow tract) is no...
Gynaecology & Obstetrics
null
e502d008-2b2d-4d51-bf8d-16e223930803
Multiple bih are commonest among .
Indians
Mongol
Caucasians
Negroes
3d
single
Negroes
Gynaecology & Obstetrics
null
33c5c465-cede-4f8e-8a99-9130a4dd3726
Given immediately in hemorrhagic shock:
Packed RBC
Colloids
Crystalloids
Isotonic fluids
2c
multi
Ans. (c) CrystalloidsRef: Bailey & Love 26th ed. /16-17* Crystalloid is the first fluid of choice for resuscitation. Immediately administer 2 L of isotonic sodium chloride solution or lactated Ringer's solution in response to shock from blood loss. Fluid administration should continue until the patient's hemodynamics b...
Surgery
Shock
56bae87c-e4fd-4917-836d-50c4efb72115
Structures passing through the sigmoid (mandibular) notch are:
Auriculotemporal nerve
Mandibular nerve
Masseteric nerve and vessels
Chorda tympani
2c
single
The upper border of the ramus of mandible is thin, and is surmounted by two processes, the coronoid process anteriorly and the condyloid process posteriorly, separated by a deep concavity, the mandibular notch, or sigmoid notch. It allows the passage of the masseteric nerve (a branch of the mandibular nerve (V3) divisi...
Anatomy
null
a024155b-39c1-4ed3-bfb9-17f61086557d
All are first rank symptoms of schizophrenia, except: TN 06; UPSC 08; Karnataka 11; NIMHANS 11; NEET 13; PGI 14
Audible thoughts
Thought broadcasting
Voice arguing or discussing or both
Perplexity
3d
multi
Ans. Perplexity
Forensic Medicine
null
31e4b89a-2134-4643-ad21-2e35db11a5ff
Intralobar sequestration of lung takes its blood supply from -
Internal mammary artery'
Descending abdominal aorta
Pulmonary artery
None of the above
1b
multi
Ans. is 'b' i.e., Descending abdominal aorta o A sequestration consists of normally developed bronchioles and alveoli supplied by systemic rather than pulmonary arteries.o This blood supply is from the Aorta either above or below the diaphragm.o Mostly fapprox 95%) this is from the descending thoracic aorta.o Other cha...
Surgery
Miscellaneous (Lung)
98c89f05-78e6-4707-9a87-5f58c9d5541d
a 25 year old female presented to the hospital on 3rdday of menstruation with complaints of high fever vomiting and rash on her trunk and extremities. on investigations she had leukocytosis and negative blood culture. she is diagnosed as :
staphylococcal food poisoning
scalded skin syndrome
toxic shock syndrome
varicella zoster infection
2c
single
TOXIC SHOCK SYNDROME Toxic shock syndrome (TSS) is an acute, febrile illness produced by a bacterial exotoxin, with a fulminating downhill course involving dysfunction of multiple organ systems. It is not unusual for the syndrome to develop from a site of bacterial colonization rather than from an infection. A woman wi...
Microbiology
All India exam
0ce08041-75d4-4142-8ffd-479727108fb7
In centrilobular (centriacinar) emphysema, there is an abnormal, permanent enlargement of the -
Respiratory bronchioles
Alveolar ducts
Small bronchi
Bronchioles
0a
multi
. Respiratory bronchioles
Pathology
null
1349d9a4-85de-4a0b-9c22-fed2a40be6ee
Absent ankle jerk and extensor plantar response is found in -
Friedreich's ataxia
Tabes dorsalis
SACD
Vit B deficiency
0a
single
null
Medicine
null
aaff3b32-064a-4b4b-a486-2c9f453524b5
Adrenaline is added to lignocaine to prolong its effect and decrease its absorption into blood stream in a ratio of :
1:50,000
1:100,000
1:200,000
1:500,000
2c
single
null
Pharmacology
null
1396001d-1606-4185-9338-20aea9759565
The treatment for a child with cherubism is
surgical excision
cosmetic surgery after puberty
radiation
Enbloc dissection
1b
single
null
Pathology
null
aa1c6808-490b-4f14-bea3-166204b191a3
Final common pathway of metabolism of carbohydrate, lipids and protein metabolism is?
Glucogenesis
Gycolysis
TCA
HMP pathway
2c
single
ANSWER: (C) TCAREF: Lippincott's biochemistry 4th ed page 109, Harper's 28th ed page 306See Biochemistry 2013 Session 2 for details of TCA/kerb cycle cyde is an aerobic pathway, because O2. is required as the final electron acceptor. Most of the body's catabolic pathways converge on the TCA cyde. Reactions such as the ...
Biochemistry
Kerbs Cycle
250b27e1-ef5c-4d9c-a2f5-941f667658d6
Stapes footplate covers :
Round window.
Oval window.
Inferior sinus tympani.
Pyramid
1b
single
Ans. is 'b' i.e. Oval window Oval window is present in the medial wall of the middle ear. It is covered by foot plate of stapes.The other window round window is also present on the medial wall. It is covered by secondary tympanic membrane.Role of these 2 windows in hearingOval window -It receives sound vibration and tr...
ENT
Anatomy of Middle Ear (Otitis Media)
6f42d1c8-efc6-4530-8639-a82d86abeee4
Newborn 7 days old with vomiting and dehydration clinical examination was normal except for hyperpigmentation of nipple. Electrolytes Na: 120 meq. K: 9 meq. most likely diagnosis -
Cong, adrenal hyperplasia
Primary hypothyroidism
Panhypopituitarism
Pyloric stenosis
0a
multi
Congenital adrenal hyperplasia due to a defect in CYP21A2 is suggested by episodes of acute adrenal insufficiency with hyponatremia, hyperkalemia, dehydration & vomiting
Medicine
null
49287ccd-a21d-4b27-9998-0f6b82efd783
Volume of air taken in and given out during normal respiration is referred to as:
IRV
TV
ERV
VC
1b
single
B i.e. T V
Physiology
null
f9aabc30-53a9-42e5-867c-765c2ae6d687
Which of following anti-gout drugs act by inhibiting the enzyme xanthine oxidase?
Probenecid
Rasburicase
Allopurinol
Sulfinpyrazone
2c
multi
DRUGS USED IN CHRONIC GOUT Group Mechanism Drugs Uric acid synthesis inhibitors Xanthine oxidase inhibitors Allopurinol, Febuxostat Uricosuric agents URAT-1 transpoer inhibitors Probenecid, Sulfinpyrazone, Benzbromarone, Lesinurad Recombinant uricase Cause oxidation of urate to allantoin Rasburicase, Pegloticase
Pharmacology
NSAIDs, Gout and Rheumatoid Ahritis
1538ad81-c5d6-44f8-8eae-8e7f79db9e1a
Salvizol is a root canal irrigants with composition:
N1- decamethylene-bis-4aminoquinaldinium-dia-cerate.
bis-dequalinium acetate.
4-chlorophenyl rings.
None.
0a
multi
SALVIZOL Salvizol is a detergent suggested for irrigating root canals during instrumentation. It is a root canal chelating irrigant, N1-decamethylene-bis-4-aminoquinaldinium-diacetate. Kaufman et al, has showe that salvizol, with a neutral pH level has a broad spectrum of bactericidal.
Dental
null
ff19a991-e8b2-49be-aa7a-53a50259d184
All the following statements about leukotriene modifers in the management of bronchial asthma are true except
May be used for acute asthma
May be used for exercise induced asthma
Zileuton is leukotriene modifer
May uncover chrug Strauss syndrome
0a
multi
Leukotriene modifers ( monteleukast,zafirulukast) may be considrrco as alternatives to low dose inhaled coicosteroids in patients with mild persistent asthma . Has no role in treating acute severe asthma Ref Harrison 19th edition pg 1673
Anatomy
Respiratory system
b72479e8-cef8-4efb-8110-f8e674fd0fe8
Which of the following passes through the foramen magnum?
Veebral aery
XII cranial nerve
Cranial pa XIth nerve
Internal carotid aery
0a
single
Foramen magnum transmits Lower end of medulla Anterior spinal aery Posterior spinal aery 4th pa of veebral aery Spinal pa of XIth nerve Other structures: Apical ligament and tip of dens, membrana tectoria, veical band of Cruciate Ligament.
Anatomy
Cranial cavity
6adc7aa4-93f0-4bf8-840e-c436dd9f6e38
The most common cause of trismus is due to infection in muscle:
Masseter
Medial pterygoid
Temporalis
All of the above
1b
multi
The most common cause of trismus is due to infection adjacent to muscles of jaw closure i.e., masseter, medial pterygoid, temporalis mostly due to involvement of pericoronal, submasseteric, and pterygo mandibular spaces.
Surgery
null
c9e64b59-0bbc-4586-9f2b-af26f288072a
A soldier from Siachen came in emergency. How will you rule out hypothermia?
Oral temperature
Rectal temperature
Nasal temperature
Infrared tympanic probe
1b
single
Ans. (B) Rectal temperature style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif">(Ref: ?)Preferred is two sites temperature check--rectal and esophageal.In the given clinical scenario rectal temperature would be preferred site to measure the core body temperature.During the low or high temp...
Medicine
Infection
1ac8c6a9-6ddd-4894-b751-7cd884f1007c
Intestinal angina is a symptom complex of the following-
Postprandial abdominal pain, weight loss, acute mesenteric vessel occlusion
Postprandial abdominal pain, weight loss, chronic mesenteric vessel occlusion
Preprandial abdominal pain, weight loss, chronic mesenteric vessel occlusion
Preprandial abdominal pain, weight gain acute mesenteric vessel occlusion
1b
single
null
Medicine
null
46b5220e-c194-4d2d-85ac-edf334c286a1
Which of these doesn't present with granulomatous Vasculitis?
Polyarteritis nodosa
Wegeners
Churg strauss syndrome
Microscopic polyangitis
3d
single
Ans. (d) Microscopic polyangitisRef: Harrison 19th ed. / 2186* MPA is characterized by pauci-immune, necrotizing, small vessel vasculitis without clinical or pathological evidence of granulomatous inflammation* The family of vasculitic granulomatoses comprise# Wegener s granulomatosis# Necrotising sarcoidal granulomato...
Medicine
Immunology and Rheumatology
e3aa9a46-6044-4638-9cf9-b1c3692f895c
The drug possessing antagonistic action at histamine, serotonin and muscarinic receptors is :
Promethazine
Terfenadine
Cyproheptadine
Hydroxyzine
2c
single
null
Pharmacology
null
6cdded3b-3a13-458c-bcbc-bb158541a1f2
Following can be used in the treatment of myoclonic seizures except –
Valporate
Carbamazepine
Topiramate
Zonisamide
1b
multi
Drugs used in myoclonic epilepsy Valproate (DOC)                           Lamotrigine         Topiramate      Clonazepam   Felbamate   Zonisamide
Pediatrics
null
01b12082-4c81-4de7-bc29-8e270ffd8339
Which histopathological type of odontogenic keratocyst is commoner, more invasive & has a greater tendency for recurrence?
Orthokeratinised
Parakeratinised
Non-keratinised
Diskeratinised
1b
single
null
Pathology
null
f2e310b1-00ed-42bc-a457-d35731e94aad
Mushroom cap sign in MRI is seen in:-
IIeocaecal TB
Pulmonary endometriosis
Ovarian endometriosis
Rectal endometriosis
3d
single
Rectosigmoid endometriosis: - The endometrial deposit on rectum causes proliferation of muscularis propria and the surrounding tissues which is seen as "mushroom cap sign" in T2 weighted MRI.
Radiology
Women Imaging
7c152931-ecc4-4619-b471-478c922dae45
Left axis deviation is seen in which of the following cyanotic congenital heart disease
TAPVC
TGA
TA
TOF
2c
single
Left axis deviation  seen in tricuspid atresia (TA), since it is the  only cyanotic congenital heart disease with Left ventricle dominance
Medicine
null
d15156dd-6810-4cbc-a473-b4825f37f41a
A patient presents with fever. Peripheral smears shows band across the erythrocytes. Diagnosis is ?
P Falciparum
P vivax
P ovate
P malariae
3d
single
Ans. is 'd' i.e., P malariae Band across erythrocytes (band-form trophozoites) is characteristic of P malariae.
Microbiology
null
e338a46c-10d4-4a71-85de-bb3e9ad66237
Which of the following statements about 'Late Expanding Phase of Demographic Cycle' is TRUE?
Bih Rate is lower than Death Rate
High Death Rate and High Bih Rate
Death Rate declines more than Bih Rate
Death Rate begins to decline while Bih Rate remains unchanged
2c
multi
In late expanding phase of demographic cycle death rates declines faster than the bih rate and there is a steady decrease in the demographic gap. In this state population grow at a steadily decreasing rate. Most of the developing countries are now at early expanding and late expanding stages of demographic cycle. Ref: ...
Social & Preventive Medicine
null
04824ae9-dc1d-4b93-9e79-93394865ada5
Which among the following is NOT a feature of Consolidation?
Increased Vocal fremitus
Dull note on percussion
Bronchial breath sounds
Trachea shifted to side of consolidation
3d
single
ANSWER: (D) Trachea shifted to side of consolidationREF: Oxford Handbook of Clinical Examination and Practical Skills by James Thomas, TanyaMonaghan Page 212"Trachea is in midline in consolidation because consolidation does not change the mediastinalposition"SIGNS OF CONSOLIDATION:Increased vocal fremitusDullness on pe...
Medicine
Pneumonia, Bronchiectasis, and Lung Abscess
6a4bf30a-5c3b-407e-a813-fa07e533e85a
A drug that is NOT contraindicated in G–6 PD deficiency is :
Primaquine
Nitrofurantoin
Dapsone
INH
3d
single
null
Pharmacology
null
c5196421-d1f9-4cfc-95b0-1055be5dbeab
Commonest salivary gland tumour in children -
Lymphoma
Adenoid cystic Ca
Pleomorphic adenoma
Mucoepidermoid Ca.
3d
single
Most common tumor of salivary gland in children - Hemangioma. Most common malignant tumor of salivary gland in children - Mucoepidermoid Carcinoma. After hemangioma, pleomorphic adenoma is the most Common salivary gland neoplasm.
Pathology
null
c1fb2fc0-8c36-43b8-ae66-fb37eeba2623
Best way to prevent hypotension during spinal anesthesia
Preloading with crystalloids
Mephentermine
Dopamine
Tredelenbug's position
0a
multi
A i.e. Preloading with crystalloids
Anaesthesia
null
1060b908-721a-4f0a-ae58-8b37e61b3092
All ofthe following are associated with normal pressure spontaneous CSF leaks, Except -
Pseudo tumor Cerebri
Empty Sella Syndrome
Encephalocele
Meningiocele
0a
multi
null
Medicine
null
5044b7a0-0fae-41cf-b43b-db46e5d18274
Following pattern in DNA electrophoresis is seen in
Apoptosis
Necrosis
Dyplasia
Metaplasia
0a
single
.
Anatomy
All India exam