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135
23afbe22-dbed-4b1f-820e-be119089ab26
End–tidal CO2 is increased to maximum level in –
Pul. embolism
Malignant hyperthermia
Extubation
Blockage of secretion
1b
single
The unanticipated doubling or tripling of end tidal CO2 is the earliest & most sensitive indicator of malignant hyperthermia. The earliest signs seen during anesthesia are masseter muscle rigidity (MMR), tachycardia, & hypercarbia.
Anaesthesia
null
9503559c-b468-4e9a-9f8f-18e2661dc4ba
Number of air changes in a drawing room per hour should be at least
5-Apr
4-Mar
3-Feb
6-May
2c
single
null
Social & Preventive Medicine
null
9a2b3dfc-1b93-413e-8719-fc2641e4d5ce
About mallory weiss sydrome true is -
Gastrointestinal reflux
Obesity
Tumour at gastroesophageal junction
Seen in alcoholics
3d
multi
Answer is 'd' i.e. Seen in alcoholics
Surgery
null
5c031a04-9536-43f6-9436-242dd64b4b35
Which of the following is done for the quick diagnosis of Erythrasma ?
Biopsy
KOH examination
Culture and sensitivity
Wood's lamp examination
3d
single
Ans is'd i.e. Wood's lamp examination(Ref. IADVL text book of dermatology 3d/e p. 236).Erythrasma is caused by infection by Coryneform bacteria.Wood's lamp examination is a commonly used test to diagnose Erythrasma.Lesion shows coral red fluorescence dre to coproporphyrin III production by the bacteria.
Skin
null
35406ea8-cd0d-498a-ac66-86ea5caf7012
Breast cancer mainly spreads to the vertebrae via -
Arterial route
Direct Invasion
Batsons venous plexus
Via Axillary lymph nodes
2c
single
Ans. is 'c' i.e., Batsons venous plexus o Three principal groups of veins are involved in the venous drainage of the thoracic wall and the breast:1) Perforating branches of the internal thoracic vein,2) Tributaries of the axillary vein, and3) Perforating branches of posterior intercostal veins.o Metastatic emboli trave...
Surgery
Breast Cancer - Prognosis and Follow-Up
1df10b32-8693-4ea8-a1a2-b85dd6206ebe
Females with vaginal atresia are characterized by all except
Lack lower portion of vagina.
Normal external genitalia.
Normal pubertal maturation.
Becomes apparent in 1st decade.
3d
multi
Vaginal atresia doesnot become apparent until menarche.
Gynaecology & Obstetrics
null
9c9d0bbd-37cb-4ff5-a4b4-53b130cba896
RPR is done for diagnosis of:
Malaria
Syphilis
Leishmaniasis
None
1b
multi
Ans. is. 'b' i. e., Syphilis
Microbiology
null
edeb15ef-d929-446a-be93-bcf5bae8d98f
A 34-year-old male patient visits a physician with complaints of fatigue, weight loss, night sweats, and "swollen glands." The physician also observes that he has an oral yeast infection. Which of the following tests would most likely reveal the cause of his problems?
A test for CD8 lymphocytes
A human T-lymphotropic virus type I (HTLV-I) test
An HIV ELISA test
A test for infectious mononucleosis
2c
single
A male patient with the presentation as outlined (fatigue, weight loss, and lymphadenopathy) must be tested for antibodies to HIV. While other antibody tests may be relevant after the primary diagnosis, they must be considered after HIV is ruled out. Ceainly, infectious mononucleosis is a possibility, but its occurrenc...
Microbiology
Immunology
cc767573-2be8-4ca3-bb2e-40b371119c69
Pantothenic acid is associated with following moiety
coenzyme A
Carboxyl
Hydroxyl
H+
0a
single
Pantothenic acid is called vitamin B5 It is ised to synthesis co enzyme A in body Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:20,21,22
Physiology
General physiology
7437a77d-8bab-476e-8c98-a64805098182
The following drug shows antiepileptic activity
Felbamate
Gabapenitine
Molindone
All of the above
3d
multi
(D) All of the above# Felbamate is an anticonvulsant drug used in the treatment of epilepsy.> It is used to treat partial seizures (with and without generalization) in adults and partial and generalized seizures associated with Lennox-Gastaut syndrome in children.> However, an increased risk of potentially fatal aplast...
Psychiatry
Miscellaneous
73720a8a-75a8-448b-bae3-5087ac90e865
A most common cause of amoebic lung abscess is -
Direct extension from liver
Hematogenous spread
Lymphatic spread
By inhalation
0a
single
Amoebic lung abscess is a result of direct spread of infection from liver to lung. The infection spreads directly through the diaphragm. The most common area of the lung involved is right lower lobe. The amoebic liver abscess ruptures and then it can involve any of the following structures. Right lung (Most commonly...
Surgery
null
551e6d05-4c64-42a3-8483-4573819ad08c
The inguinal canal is NOT bounded posteriorly by -a) Transversalis fascia b) Internal oblique tendonc) Conjoint tendond) Lacunar ligament
bd
ab
acd
bcd
0a
single
Inguinal canal- Posterior wall formation -        Medial 2/3- Conjoint tendon and reflected part of inguinal ligament -        Whole- Fascia transversalis, extraperitoneal connective tissue, parietal peritoneum.
Anatomy
null
e7131807-11ed-474f-b332-083cc186113a
Single base pair substitution is related to which of the following?
RFLP
PCR
FISH
Southern blot
0a
single
The term RFLP (Restriction Fragment Length Polymorphisms) refers to single base pair substitutions in germ line DNA of different individuals that either destroys or creates new recognition site for a given restriction enzyme. PCR is used to amplify a specific region of a DNA strand (the DNA target). FISH is atechnique ...
Biochemistry
null
ae8b3fb4-6e64-435b-a36e-030e14ff00be
An investigator is studying a potential new antiarrhythmic. Eighty healthy test subjects are receiving various doses of the drug. Adverse effects and the drug’s pharmacokinetics are assessed Which of the following steps in the drug development process does this represent?
New drug application (NDA)
Phase I
Phase II
Phase Ill
1b
multi
null
Social & Preventive Medicine
null
eacad337-89b4-4982-baab-52289987b348
A 45-year-old woman undergoes an uneventful laparoscopic cholecystectomy for which she receives 1 dose of cephalosporin. One week later, she returns to the emergency room with fever, nausea, and copious diarrhea and is suspected of having pseudomembranous colitis. She is afebrile and has no peritoneal signs on abdomina...
Administration of an antidiarrheal agent
Exploratory laparotomy with left hemi-colectomy and colostomy
Exploratory laparotomy with subtotal abdominal colectomy and ileostomy
Administration of oral metronidazole
3d
single
Treatment of C difficile colitis is metronidazole for firstline therapy and oral vancomycin as a second-tier agent. Recurrence appears in up to 20% of patients. Indications for surgical treatment are intractable disease, failure of medical therapy, toxic megacolon, and colonic perforation; surgical therapy consists of ...
Anaesthesia
Preoperative assessment and monitoring in anaesthesia
b898becc-c6e5-4275-837a-e2bd4b839932
Antidote of choice for Belladonna poisoning -
Disulfiram
Atropine
Physostigmine
Flumazanil
2c
single
Ans. is 'c' i.e., Physostigmineo Antidote of choice for belladonna (atropa belladonna or atropine) poisoning - Physostigmine.PoisonAntidotesAcetominaphen (paracetamol)N-Acetyl cysteineNitrites, cyanidesAmyl nitrite + sodium nitrite + sodium thiosulphateOrganophosphates (anticholinesterase)Atropine and oximesDigoxinDizi...
Forensic Medicine
Forensic Toxicology - Concepts, Statutes, Evidence, and Techniques
059d0b20-b800-42af-97b6-6b44a9b598ae
All of the following are true about amebic liver abscess except:
Trophozoites in stool are essential for clinical diagnosis
Mostly asymptomatic
More common in males than females
Rarely affects brain, eye and skin
0a
multi
Ans. a. Trophozoites in stool are essential for clinical diagnosis
Microbiology
null
196d9f9b-de52-4822-952e-b26445e892d7
In superficial second degree burns, re-epithelialisation occurs around:
<1 week
2 weeks
3 weeks
4 weeks
1b
single
Characterstics of Superficial Second Degree Burns Involve upper layer of dermis ( Papillary dermis) Erythematous BLISTERS are seen Blanch on touch Painful Heals without scarring in 7-14 days
Surgery
Burns
7c12692e-244e-48ce-a11a-0425063f84f2
A 20 years old nulliparous women is an oral contraceptives pills. She is currently diagnosed as having pulmonary tuberculosis. Which antituberculous drug decreases the effect of OCPs?
INH
Pyrazinamide
Ethambutol
Rifampicin
3d
single
Because rifampin potently induces CYPs 1A2, 2C9, 2C19, and 3A4, its administration results in a decreased t1/2 for a number of compounds, including: HIV protease and non-nucleoside reverse transcriptase inhibitors Digitoxin Digoxin Quinidine Disopyramide Mexiletine Tocainide Ketoconazole Propranolol Metoprolol Clofibra...
Gynaecology & Obstetrics
null
915f4dec-f6e4-412d-89aa-7efa5c092fe4
Initial drug of choice in a child with status epilepticus
Lorazepam
Phenobarbitone
Valproate
Phenytoin
0a
single
Prompt treatment with benzodiazepines is the first-line treatment of status epilepticus, but many patients will need additional treatment with additional medications including phenytoin, valproic acid, phenobarbital, or levetiracetam. The Neurocritical Care Society's guideline states that benzodiazepines remain the "em...
Pediatrics
Central Nervous system
73564a51-b790-4540-8d90-68e603dccc9f
Marquios disease not seen is
Corneal opacity
Mental retardation
Stunted growth
Absent clavicle
1b
single
Morquio syndrome is an inherited disease of metabolism in which the body is missing or doesn&;t have enough of a substance needed to break down long chains of sugar molecules called glycosaminoglycans (formerly called mucopolysaccharides).SymptomsAbnormal development of bones, including the spineBell-shaped chest with ...
Biochemistry
Metabolism of carbohydrate
7945820f-3d40-44d6-8968-1b422397529e
Corneal dystrophies are –a) Macularb) Granularc) Latticed) Moorense) Fuchs
bcde
abcd
acde
abce
3d
single
Macular, granular and lattice dystrophies are stromal corneal dystrophies. Fuch's dystrophy is posterior (endothelial) corneal dystrophy.
Ophthalmology
null
81010c36-8dcd-478b-bf13-d3a649aec32d
Leaving the capsule behind in cataract surgery is advantageous because it –a) Prevents cystoid macular edemab) Decreases endothelial damagec) Progressively improves visiond) Decreased chance of retinal detachmente) Decreased chance of endophthalmitis
abcd
bcde
acde
abde
3d
single
First keep in your mind that any of the described complication can occur with either ICCE or ECCE. However, ECCE (leaving capsule behind) decreases the chances of many complications. Complications decreased by ECCE are :- Vitreous prolapse & loss Endophthalmitis      Cystoid macular edema Aphakic glaucoma        Fibr...
Ophthalmology
null
30219f05-b601-4049-b263-3d542307a77f
Pointing index sign is seen in ---- nerve palsy -
Ulnar
Radial
Median
Axillary
2c
single
Pointing index (oschner's clasp test) is seen in high median nerve palsy.
Orthopaedics
null
763d8dcf-72d2-42d9-86f6-f5cfdf83ab08
Investigation of choice in upper GI bleeding is
Ba swallow
X-ray
Endoscopy
Ultrasound
2c
multi
"Upper endoscopy is the test of choice in patients with UGIB" "Whenever GI haemorrhage is thought to derive from a source proximal to the ligament of Treitz, or whenever the issue is in doubt, the first invasive diagnostic maneuvre should be upper GI flexible endoscopy. This technique has a diagnostic accuracy of appro...
Anatomy
G.I.T
a078459f-30bc-43e9-81db-3960d111c6a4
Jack stone calculi is seen in which anatomic part -
Prostate
Kidney
Ureter
Bladder
3d
single
null
Surgery
null
31abfa6a-9836-457e-9f3d-db319fc2e842
A rapid method of chromosome identification in intersex is -
FISH
PCR
SSCP
Karyotyping
0a
single
Ans is a. ie. FISH * The above-mentioned site writes about FISH- * "FISH can be used in interphase cells to determine the chromosome number of one or more chromosomes as well as to detect some specific chromosome rearrangements that are characteristic for certain cancers. The primary advantage of interphase FISH is tha...
Unknown
null
701d25c4-c8ad-4273-8baa-ffa96d680b9a
Which one of the following statements about EEG is true?
Alpha rhythm is most marked at parieto-occipital area
Beta rhythm is most marked at region below mastoid
In REM sleep, patient is awake
EPSP and IPSP of the cortical cells acting as dipoles
0a
multi
(A) Alpha rhythm is most marked at parieto-occipital area # Alpha Rhythm > In adult humans who are awake but at rest with the mind wandering and the eyes closed, the most prominent component of the EEG is fairly regular pattern of waves at a frequency of 8-12 Hz and an amplitude of 50-100 uV when recorded from the scal...
Physiology
Nervous System
4040a79f-7c7e-4a58-9b65-464ab8076b30
The vasodilator involved in autoregulation of the coronary blood flow is:
NO
ACh
Adenosine
CO2
2c
single
NO and adenosine both fit as the probable candidates. However, single best response would be adenosine, and NO could be taken as the mediator of the adenosine action. As per the Berne's hypothesis: When myocardial O2 demand increases (as during increased hea rate) -> increased breakdown of ATP in the myocardial cells -...
Physiology
Circulation
c41356f4-8a47-4f6b-be6b-7fe60bed1c9e
Which one of the following enzymes provides a link between glycolysis and the citric acid cycle?
Lactate dehydrogenase
Pyruvate Kinase
Citrate synthase
Pyruvate dehydrogenase
3d
single
PDH complex consist of 3 Enzymes and 5 Coenzymes Three enzymes are: Pyruvate Dehydrogenase bound to Thiamin Diphosphate Dihydrolipoyl Transacetylase, the prosthetic group is oxidised Lipomide Dihydrolipoyl  Dehydrogenase, contains FAD. Coenzymes (very important) Thiamine Diphosphate (TDP) Lipomide Coenzyme A FAD NAD...
Biochemistry
null
06790194-a415-4f7d-b5f4-3ef0248f6afc
Most common cause of knock knee
Osteo-arthritis
Rheumatoid arthritis
Idiopathic
Trauma
2c
single
null
Orthopaedics
null
0f038565-7dc2-4457-9637-c3f6c18011af
A 30-year-old male HIV positive on antiretroviral therapy has pain in right hip region. Flexion, abduction and external rotation deformity of right hip for 2 months, what is the most likely diagnosis?
Avascular necrosis
TB hip
Transient synovitis
Septic arthritis
1b
single
(b) TB hip in HIVAVN hip in HIVIncidenceMore CommonLess CommonDeformityFABER-stage of synovitis may be prolonged on treatment, then subsequently with onset of arthritis - FADIRLimitation of abduction and internal rotation so initially position is adduction and external rotation (opposite to movements limited) and than ...
Orthopaedics
TB of the Hip, Knee, Other Joints
7ece8365-8305-49ae-9aff-d8dd268172ce
A 32 year old male is diagnosed of having acute myeloid leukemia. His total WBC count was less than normal initially. Which of the following factor has a bad prognosis in AML?
Monosomies of chromosomes
Young age
Patients with t(15;17)
Low WBC count
0a
multi
Prognostic factors of acute myeloid leukemia (AML): Advancing age is associated with a poorer prognosis, in pa because of its influence on the patient's ability to survive induction therapy. The leukemic cells in elderly patients more commonly express the multidrug resistance 1 (MDR1) efflux pump that conveys resistanc...
Pathology
null
9d2b5496-a9ca-43db-93a8-3a2cb8e419a7
All of these are true about GnRH analogues used in treatment of endometriosis , EXCEPT?
Continuous administration causes downregulation of pituitary gonadotropins
The risk of osteoporosis decreases with prolonged use as the estrogen mediated osteoblastic action continues
Add back therapy includes estrogens
Discontinuation causes recurrence
1b
multi
GnRH is given continuously to downregulate and suppress pituitary gonadotropins and cause atrophy of endometriotic tissue. The risk of osteoporosis increases after prolonged use as the estrogen mediated osteoblastic action stops while the estrogen independent osteoclast action continues Add back therapy is given to red...
Gynaecology & Obstetrics
Endometriosis, Adenomyosis
2b38cab7-bf9c-4de7-af88-3910153c80b2
Final common metabolism of atracurium, mivacurium and succinylcholine are by:
Conjugation
Reduction
Hydrolysis
Acetylation
2c
single
Ans: c (Hydrolysis) Ref: KDT, 6 ed, p.25, 345; Harper 27 ed, p.96The final common pathway in the metabolism of all the three involves hydrolysis by an esterase.The cleavage of a drug molecule by taking up a water molecule; occurs in liver, intestine, plasma and other tissues.E.g.: choline esters, lignocaine, procaine, ...
Pharmacology
Anaesthesia
3339d8b4-40ed-4043-aa68-ef0e4d266df7
A 24 year old male presents with altered sensorium and rapid shallow breathing. ABG shows:pH 7.2, sodium 140, bicarbonate 10 and chloride 98. Probable diagnosis is -
Renal tubular acidosis
DKA
Ethylene glycol poisoning
Amphetamine toxicity
1b
multi
usually happens because your body doesn't have enough insulin. Your cells can't use the sugar in your blood for energy, so they use fat for fuel instead. Burning fat makes acids called ketones and, if the process goes on for a while, they could build up in your blood. That excess can change the chemical balance of your...
Medicine
Toxicology
21c41da0-ff71-43c8-a381-250d293278ab
The Colposcopic features suggestive of malignancy are all except :
Condyloma
Vascular atypia
Punctation
White epithelium
3d
multi
White epithelium
Gynaecology & Obstetrics
null
bf6fabc7-a2e1-40e3-a651-560dd4db2b6a
A 25-year-old woman presents to the emergency department with symptoms of nausea and vomiting of 2 days duration. She is not on any medications and was previously well until now. The physical examination is normal except for a postural drop in her blood pressure from 110/80 mm Hg supine to 90/80 mm Hg standing. Her ser...
potassium
sodium
bicarbonate
urea
3d
multi
Urea is filtered at the glomerulus, and thereafter, any movement in or out of tubules is a passive process depending on gradients, not secretion. Reabsorption of urea in the distal tubule and collecting duct, when urine flow is reduced, results in the disproportionate elevation of urea nitrogen over creatinine in prere...
Medicine
Oncology
7c6d1e8e-7198-4fa8-8fb5-2e9b7b870193
Henoch Schnolein Purpura may rarely cause -
Intussuception
Volvulus
Atrial fibrillation
Hernia
0a
single
null
Surgery
null
d6c4a62b-f438-41ec-9a93-78516fad6926
All of the following are contrast radiographs except:
Arthrography
Tomography
Sialography
Arthrotomography
1b
multi
null
Radiology
null
5eea33c5-89e6-48b1-a14a-e6d523152b82
Definitive treatment of hypermagnesemia is?
Calcium gluconate
IV fluids
Hemodialysis
Exchange resins
2c
single
Hemodialysis REF: Harrison's 17th ed chapter 346 HYPERMAGNESEMIA: TREATMENT Successful treatment of hypermagnesemia generally involves identifying and interrupting the source of magnesium and employing measures to increase magnesium clearance from the BCF. Use of magnesium-free cathaics or enemas may be helpful in clea...
Surgery
null
9b6a828b-4539-4cc3-b14d-bb9c346cfe55
Which of the following is not true of polymethylmethacrylate?
Knoop hardness number 18 to 20
Tensile strength of 60 MPa
Density of 1.13 g/cm3
Modulus of elasticity of 3.4 GPa
3d
multi
PMMA is a transparent resin of water-like clarity that is transparent to light in the visible and ultraviolet range down to a wavelength of 250 nm. It is a hard resin with a Knoop hardness number of 18 to 20 KHN. It has a tensile strength approximately 60 MPa, a density of 1.19 g/cm3 and a modulus of elasticity of appr...
Dental
null
9e305080-8ea1-4494-abe0-2ed57d3ae128
Kaplan Meier method is used for -
Survival
Prevalence
Incidence
Frequency
0a
single
null
Social & Preventive Medicine
null
9a688eae-f889-421b-9cda-15557746caa0
Most common organism involving allograft transplant:
Bacteria
Fungi
Virus
Parasite
2c
multi
Ans. (c) VirusesRef: Bailey 26th edition, Page 1415* Most common infection in allograft transplant--Viral infection* Risk of infection is the greatest during first 6 months* Chemoprophylaxis is important for high-risk patients* Cytomegalovirus is a major problem* Most common malignancy after transplant: Post-transplant...
Surgery
Transplantation
4e953881-b544-4fbf-ba88-72940d60d9e1
A young boy presents with dark patches with itching. On rubbing there is appearance of wheal. Diagnosis is -
Addison's disease
Urticaria pigmentosa
Chronic idiopathic urticaria
Erythema multiforme
1b
single
Ans is 'b' i.e. Urticaria pigmentosa Urticaria pigmentosao Urticaria pigmentosa (also known as "Generalized eruption of cutaneous mastocytosis (childhood type)) is the most common form of cutaneous mastocytosiso Urticaria pigmentosa is most common in children. It can also occur in adultso Urticaria pigmentosa occurs wh...
Skin
Eosinophilic Dermatoses
2f9b182a-225c-4da0-ad8b-5a32eacb6fff
True about western blot:
Separation of proteins are based on mass
SDS-PAGE electrophesis is used for separation
Enzyme linked antibodies are used
All
3d
multi
A i.e. Separation of proteins are based on mass; B i.e. SDS-PAGE electrophesis is used for separation; C i.e. Enzyme linked antibodies are used
Medicine
null
ac93f9e6-92c4-4101-814c-5df35ddcf937
Adult polycystic kidney disease is-
Autosomal dominant
Autosomal recessive
X-linked
Mitochondria
0a
single
Ans. is 'a' i.e., Autosomal dominant Summary of Renal cvstic disease InheritancePathologic featuresClinical features of ComplicationsTypical outcomeAdult polycystic kidney diseaseAutosomaldominantLarge multicystie kidneys, liver cysts, berry aneurysmsHematuria, flank, pain, urinary tract infection, renal stones, hypert...
Pathology
Chronic and Cystic Diseases
0b5420bb-e890-44d3-86e1-4640003da84a
Imiquimod is used in treatment of anogenital was acts mainly as:-
Antifungal
Antiviral
Immunomodulator
Keratolytic
2c
single
Topical immunomodulation with imiquimod 5% cream is used for treatment of: genital was superficial basal cell carcinoma actinic keratoses Acts on Toll-like receptor 7 (TLR-7). This is a cell surface receptor found on cells of monocyte lineage. Interaction of TLR-7 with ligands activates a signalling pathway, leading to...
Dental
Viral infections
570ebcb6-fe07-4408-8fb9-9336de01a08e
The key enzyme in urea synthesis is -
Urease
Carbamoyl phosphate synthase-I
Arginase
Ornithine
1b
single
Ans-B
Unknown
null
30934853-dd57-4372-86ec-91a17451882c
Ovulation is presumed to have occurred if progesterone level is __________ on day 21
0.3 ng / mL
3 ng / mL
30 ng / mL
300ng / mL
1b
single
Ovulation can be safely assumed to have occurred if progesterone level exceeds 3 ng / mL on cycle day 21.
Gynaecology & Obstetrics
null
779280a9-db83-49b6-b7f8-c21229b633c4
A 37-year-old obese female presents with pain in her left wrist and abnormal sensations, numbness, burning and tingling in her left thumb, index, and middle fingers and some part of ring finger. The pain is severe and wakes her up at night. She works as a typist and pain increases with typing all day. Nerve conduction ...
Atrophied adductor pollicis.
Inability to oppose the thumb to other digits.
Flattened hypothenar eminence
Paresthesia of thenar eminence
1b
multi
Answer: b) Inability to oppose the thumb to other digits.Patient is suffering from "carpal tunnel syndrome".It is a medical condition in which the median nerve is compressed as it passes through the carpal tunnel deep to the flexor retinaculum at the wrist.The patient's occupation as typist may have predisposed the pat...
Orthopaedics
Peripheral Nerve Injuries
cc9e0284-58f7-4a82-8003-edb12f136a32
Which of the following is a characteristic feature on culture of Streptococcus pneumoniae organism?
Alpha-hemolytic colonies inhibited by optochin on blood agar and lysed by bile
Beta-hemolytic colonies that are bacitracin-resistant on blood agar
Beta-hemolytic colonies that are inhibited by bacitracin on blood agar
Catalase-negative organisms that hydrolyze esculin in 40% bile and 6.5% NaCI
0a
single
These findings are used to identify Streptococcus pneumoniae. Optochin sensitivity is used to differentiate the viridans streptococci (resistant) from S. pneumoniae (sensitive). Another test used to identify S. pneumoniae is the Quellung reaction. The only medically impoant optochin-sensitive organism that gives a posi...
Microbiology
null
341786bd-a17e-4abc-a616-8bae05f8c64a
A person had an episode of dengue serotype 1, after 2 years with serotype 2. What will be effect of this episode?
Mild ds d/t neutralizing abs present
Increased chances of DHF
No chances of DHF
No effect on present illness
1b
single
Ans. b. Increased chances of DHFPATHOGENESIS OF DENGUE VIRUSPrimarily dengue infection occurs when a person is infected with dengue virus for the first time with any one serotype.Months to years later, a more severe form of dengue illness may appear (Called secondary dengue infection) due to infection with another seco...
Medicine
Infection
c55c1526-4fce-4d10-bed4-7462834321f2
Insane paresis is associated with -
Syphilis
Leishmaniasis
Yellow fever
Nesseria meningitis
0a
single
Ans. is 'a' i.e., Syphilis General paresis of insane Is a form of neurosyphilis, peaks in incidence 10 to 20 years after untreated Treponemapalliduminfection.It often stas with subtle cognitive and emotional changes, such as problems with concentration and irritability, and, if untreated, can lead to memory loss, confa...
Pathology
null
f5d4b052-c522-43ce-80bc-c0943ab336ff
A two-month-old infant is brought to the hospital emergency with marked respiratory distress. On examination, the infant has cyanosis and bilateral crepitations. Hea rate is 180/min, respiratory rate 56/min and the liver span 7.5 cm. The child has had repeated episodes of fever, cough and respiratory distress since the...
Congenital methemoglobinemia
Transposition of great aeries
Cystic fibrosis
Tetralogy of Fallot
1b
multi
Ans. is 'b' i.e., Transposition of great aeries
Pediatrics
null
0bf4c9ba-9892-45df-9bbe-44fcdfcf6825
Facilitated diffusion is characterized by all except
Vmax
Competitive inhibition
Requires energy
Specificity
2c
multi
This process is called passive transpo orfacilitated diffusion, and does not require energy. The solute can move "uphill," from regions of lower to higher concentration. This process is called active transpo, and requiressome form of chemical energy. Ref ganong's review of medical physiology 25e p102
Physiology
All India exam
612842c4-4aea-40a5-995c-64ee33be65c4
Which of the following is an enrichment media: September 2009
Alkaline peptone water
Monsour's taurocholate Tellurite peptone water
Selenite F broth
All of the above
3d
multi
Ans. D: All of the above Culture media may be classified into several categories depending on their composition or use. A chemically-defined (synthetic) medium is one in which the exact chemical composition is known. A complex (undefined) medium is one in which the exact chemical constitution of the medium is not known...
Microbiology
null
707dcf60-d95e-4736-b2ef-3f89a79f5acd
Which prostaglandin is used in NSAID induced ulcer?
Misoprostol
Carboprost
Miazapine
Miprinone
0a
multi
Ans. is 'a' i.e., Misoprostal o Misoprostol (PGE1 analogue) is used for prevention and treatment of NSAID induced ulcer, but DOC is PPI.
Pharmacology
null
5ec3f0d8-b40d-40e1-af26-0415d7e3a17b
Which one of the following is not true regarding fibrolamellar carcinoma?
Seen in young adults
Better prognosis than HCC
Associated with HBV infection
Elevated AFP is not seen
2c
multi
Unlike HCC, fibrolamellar Ca is not associated with HBV infection. Fibrolamellar carcinoma characteristically manifests as a large hepatic mass in adolescents or young adults. Most patients present in the 2nd or 3rd decade of life. Cirrhosis; elevated a-fetoprotein levels; and typical risk factors for hepatocellular ca...
Medicine
null
ce4ede3c-e2ef-4eb3-9d30-f4e14e239d29
35 year old female diagnosed to have hyper thyroid disorder. Her thyroid follicle lined by
Simple columnar
Simple squamous
Simple cuboidal
Ciliated columnar
0a
single
Normal thyroid follicle - simple cuboidal Hyper thyroid follicle - simple columnar Hypo thyroid follicle - simple cuboidal
Anatomy
Epithelial tissue
82b7f1df-6e0f-4d28-ba55-c38b362ea12f
Drugs used for treating schizophrenia are chiefly:March 2010
Antimaniac
Antidepressant
Antihistaminics
Antipsychotic
3d
single
Ans. D: AntipsychoticAntipsychotics have been a mainstay of therapy for schizophrenia since the introduction of chlorpromazine in the mid-1950s, which revolutionized treatment.Atypical/second generation antipsychotic drugs, such as riseperidone, olanzapine, quetiapine. Aripiprazole, and ziprasidone, are more commonly u...
Psychiatry
null
ff137b47-fab2-4256-93f1-b29156af3c4e
Most common glial tumor
Ependymomas
Astrocytoma
Meningioma
Neurofibroma
1b
single
Astrocytomas are the most common tumours among all other gliomas .....and in astrocytoma infiltrating type has an occurrence of 80 percent of all cases. REF : Robbins and cotrans , 9e , pg : 1306
Pathology
Endocrinology
fb0c3e9f-8d53-411e-a2f1-e2a1b0e4143e
The malunion of supracondylar fracture of the humerus most commonly leads to:
Flexion deformity
Cubitus varus
Cubitus valgus
Extension deformity
1b
single
Ans. is 'b' i.e. Cubitus varus Repeat Q no. 146 Dec 1997Malunion is the most common complication of a supracondylar fracture and results in a cubitus varus deformity also k/a Gun stock deformity.Although cubitus varus is cosmetically unsightly, it does not have any significant functional disability, so it is corrected ...
Orthopaedics
Supracondylar Fracture
5b6b3244-eac6-476d-aedf-78c76558209e
A good indicator of the availability, utilization and effectiveness of health care services in a country is?
Maternal moality rate
Hospital bed occupancy rate
Infant moality rate
DALY's
3d
single
Ans. is 'c' i.e., Infant moality rate o IMR is considered a sensitive index of health services as it reflects maternal care, perinatal care, child rearing practices, nutritional practices, and socioeconomic conditions in which people live as well as availability, effectiveness and utilization of health care services. "...
Social & Preventive Medicine
null
95658a39-3e66-484f-b531-3270a186e3eb
Following are complications of chicken pox except
Meningitis
Pneumonia
Enteritis
Reyes Syndrome
2c
multi
Chicken pox is caused by varicella zoster virus ,a DNA virus of Herpes virus family . It is present in respiratory secretions and skin lesions of an affected child . The poal of entry is the respiratory tract. Secondary bacterial infections of skin lesions is fairly common and occasionally result in necrotising fasciti...
Pediatrics
Infectious disease
1e668d12-42d8-46a0-ad34-866efa8fc690
One day after a casual sexual encounter with a bisexual man recently diagnosed as antibody-positive for HIV, a patient is concerned about whether she may have become infected. A negative antibody titer is obtained. To test for seroconversion, when is the earliest you should reschedule repeat antibody testing after this...
1 to 2 weeks
16 to 20 weeks
6 to 12 weeks
12 to 15 weeks
2c
single
Persons at high risk for infection by human immunodeficiency virus (HIV) include homosexuals, bisexual males, women having sex with a bisexual or homosexual paner, intravenous drug users, and hemophiliacs. Antibody titer usually becomes positive 6 to 12 weeks after exposure, Because of occasional delayed appearance of ...
Gynaecology & Obstetrics
Genital Tract Infections (Too hot to handle!)
064492f8-cfba-44e7-a4a5-a60c13c8dba8
when Va/Q is INFINITY , it means
The pO2 of alveolar air is 159mmHg and PCO2 is40mmHg
paial pressure of alveolar gas is same as deadspae
Paial pressure of O2 and CO2 are equal
ALL TH E ABOVE
1b
multi
V/Q IS INFINITY WHEN DEAD SPACE IS 0 REF : HARISSONS 21ST ED
Medicine
All India exam
e1ef9aef-429f-45a4-a9eb-19807aa66db4
Dose of levonorgestrel used for emergency contraception:-
0.75 mg within 72 hours
1.5 mg within 72 hours
1.5 ug within 72 hours
3 ug within 72 hours
1b
single
Levonorgestrel is Doc for emergency contraception 0.75 mg tablets ( 2 tablets) 12 hrs apa. 1.5 mg tablet ( 1 tablet ) within 72 hrs. This is the only method of emergency contraception approved for use by Drug Controller of India Note:- IUCD - used up to 5th day after intercourse.
Gynaecology & Obstetrics
Contraceptives
4e27c57c-40a7-4841-827b-f0560e36c9c3
pANCA positive vasculitis is
Wegener's granulomatosis
Churg - Strauss syndrome
Polyaeritis nodosa
All of the above
1b
multi
Answer- b. Churg - Strauss syndromePANCATypically found in:MicroscopicpolyangiitisChurg-StrausssyndromeIdiopathiccrescenticglomerulonephritisGoodpasteur'ssyndrome.pANCA's are also associated with ceain non-vasculitic entities such as ceain rheumatic and nonrheumatic autoimmune diseases, Inflammatory bowel diseases, cea...
Medicine
null
2c03b258-facc-42ef-a418-97f077c372f6
Earliest feature in Multiple sclerosis is -
Optic neuritis
Inter nuclear ophthalmologia
Ataxia
Weakness
0a
single
null
Medicine
null
101bc391-d7cc-4c5c-8c31-486118d845b1
Who proposed the nasal septum "theory of craniofacial growth"?
Mass
Sicher
Vander Linden
Latham
3d
single
null
Dental
null
7df2a179-3988-4abb-bfae-5291b328f2e0
Transmission of HIV infection from infected mother to child occurs most commonly during -
Antenatal stage
Before delivery
Duringlabour
During lactation
2c
single
Ans. is 'c' i.e.. During labour
Gynaecology & Obstetrics
Infectious Diseases
d36d0bd1-4055-4ee9-a1b4-9e463214e39b
The position adopted for tonsillectomy is also adopted for this procedure. -
Direct laryngoscopy
Bronchoscopy
Tracheostomy
Indirect laryngoscopy
2c
single
The position of a patient during tonsillectomy is Rose's position, i.e. patient lies supine with head extended by placing a pillow under the shoulder. Rose's position is used in the ENT for : Tonsillectomy, Adenoidectomy, Tracheostomy.
ENT
null
28c2976d-cba8-49ce-b6c8-c852cc16fc6a
Ectopia lends is a feature of:
Marfan's syndrome
Homocystinuria
Weil-marchisani syndrome
All of the above
3d
multi
Ans. d (All of the above)CAUSES OF LENS DISLOCATIONDiseases that can be associated with subluxation or dislocation of the lens# Sharp and in particular blunt injuries (globe contusion)# Metabolic disorders- Marfan syndrome- Homocystinuria- Weil-Marchesani syndrome- Hyperlysinemia- Sulfite oxidase deficiency- Ehlers-Dan...
Ophthalmology
Lens
2627c8d8-8ac6-4ff3-b662-c2b4cde86285
Onset of post spinal headache is usually at___ hours after spinal anesthesia
0-6
12-Jun
Dec-72
72-96
2c
multi
Post spinal headache or post dural puncture headache has onset usually on second or third day post procedure. It is an occipital type of headache, aggravated on sitting and relieved in recumbent position
Anaesthesia
Regional anaesthesia
0ad0e571-b849-41ff-b6ef-13305fc2e36a
Indira Gandhi Matritva Sahyog Yojana is for ?
> 65 years old
> 50 years old
> 30 years old
> 19 years old
3d
single
Ans. is d i.e., > 19 years old o The Indira Gandhi Matritva Sahyog Yojana (IGMSY) is a flagship program of the government of India introduced in 2010 under the Ministry of Women and Child Development. o It is a conditional cash transfer scheme that targets pregnant and lactating women 19 years of age and older who have...
Social & Preventive Medicine
null
26995a41-bf7c-408c-a73c-3fa2b01ccba0
All of the following may be causes of precocious puberty in girls except –
Hypothalamic harnartoma
Mc Cuone Albright syndrome
Granulosa cell tumor of human ovary
Congential 21–α hydroxylase deficiency
3d
multi
Congenital 21 hydroxylase deficiency causes precocious puberty in male due to excess of androgens. In female, it results in virilization.
Pediatrics
null
2c53a5ef-6e32-4ffb-994f-35424d563e35
Phencyclidine is also known by all except
Cadillac
Peace pill
Rocket fuel
White lightning
3d
multi
Phencyclidine - other names - Cadillac, Peace pill, Rocket fuel, Hog, Goon, Angel dust, Super grass - It is used as psychedelic and hallucinogen. - LSD - White lightening - Phencyclidine also causes Dissociative Anaesthesia.
Forensic Medicine
Toxicology - 1
7f9cd7d7-7dc5-4a79-8ad6-778b3bbd2860
Death caused by exclusion of air from the lungs by means other than compression at neck and drowning.
Suffocation
Strangulation
Traumatic asphyxia
Sexual asphyxia
0a
single
Suffocation literally means to die as a result of not being able to breath or to have difficulty in breathing. Deprivation of oxygen can be by one of the following ways. By lack of oxygen in the atmosphere, so called environmental suffocation. From obstruction of air passages by means other than Compression of neck and...
Forensic Medicine
Asphyxia
3d45e4d8-2b08-4ee8-8e56-30bcce99cb0d
Which of the following is classified under Grade II acute cholecystitis according to the Tokyo Consensus Guidelines?
Presence of multiorgan dysfunction
WBC count > 11000/mm3
Mild local inflammation
Duration of complaints >72 hours
3d
single
Tokyo Consensus Guidelines for severity grading of acute cholecystitis: Grade I (mild) acute cholecystitis Acute cholecystitis in a healthy person with no organ dysfunction and mild inflammatory changes in the gallbladder Grade II (moderate) acute cholecystitis Associated with any one of the following:1. Elevated WBC c...
Surgery
Gallbladder
1c98ce11-3f3a-4f84-bf1c-b5518dfbe104
Not true about Fuch's corneal dystrophy -
Glaucoma is its common association
Endothelial dystrophy
Unilateral condition
Occurs in old age
2c
multi
Fuchs dystrophy is frequently seen as a slowly progressive bilateral condition affecting females more than males, usually between fifth and seventh decade of life. Primary open angle glaucoma is its common association.Reference:Comprehensive ophthalmology,AK Khurana,4th edition,page no.118
Ophthalmology
Cornea and sclera
06c1ca64-051c-40f7-b1b7-ac2f722873ca
A lesion of the optic radiation involving the Meyer's loop causes -
Homonymus hemianiopia
Superior quadrantanopia
Inferior quadrantanopia
Central scotoma.
1b
single
Meyer's loops are the inferior most fibres of optic radiation. Damage to inferior fibres cause superior quadrantanopia.
Ophthalmology
null
78829adf-46e6-4c37-b03c-d75e60228987
300 diseased people were made to undergo a test of which only 60 were positive. 40 people were found to be false positive for the test. The positive predictive value of the test is:
40/100
60/100
40/300
240/300
1b
multi
Ans: b (60/100)Ref: Park, 20th ed. Pg. 126 19 ed., Pg. 119Screening test resultsDiagnosisTotalDiseasedNot diseasedPositiveNegativea (True positive)c (False negative)b (False positive)d (True negative)a+bc+dTotala+cb+da+b+c+dSensitivity = a/ (a+c) x 1 (X)Specificity = d/ (b+d) x 1 (M)Predictive value of positive test= a...
Social & Preventive Medicine
Biostatistics
7cebf49d-d714-4b53-948c-6941d92615c1
Barrette's oesophagus is diagnosed by
Squamous metaplasia
Intestinal metaplasia
Squamous dysplasia
Intestinal dysplasia
1b
single
(B) Intestinal metaplasia # Barrett's esophagus is a serious complication of GERD.> In Barrett's esophagus, normal tissue lining the esophagus changes to tissue that resembles the lining of the intestine(columnar epithelium).> Barrett's esophagus is marked by the presence of columnar epithelia in the lower esophagus, r...
Pathology
Misc.
9d177b62-78e0-4e70-a310-e59f02e78bd1
A 50-year-old HIV seropositive male presented to the ER with multiple episodes of generalized tonic-clonic seizures. Patient is not on HAA. CD4 count was done and it was 45/ microL. O/E, Mildly arousable Disoriented No nuchal rigidity or focal neurological deficits Gadolinium enhanced MRI and MR spectroscopy were condu...
Caspofungin
Streptokinase
Pyrimethamine + Sulphadiazine
Voriconazole
2c
multi
This is a case of cerebral toxoplasmosis in the setting of HIV-AIDS. MRI shows a number of lesions in the brain parenchyma with surrounding edema - suggestive of toxoplasmosis. Increased lipid peak and decreased choline peak on spectroscopy differentiates it from primary CNS lymphoma. Patients of HIV with CD4 count < 1...
Unknown
Integrated QBank
83ad01f1-b286-42af-b1aa-8c7e904157d8
The recent treatment of short bridle passable stricture of urethra in the penile and bulbous urethra is-
Internal urethrotomy with Thompson-Walker's urethrotome
Optical internal urethrotomy
Syme's operation
Wheelhouse operation
1b
single
Campbell says “The data show that strictures at the bulbous urethra that are < 1.5 cm in length and not associated with dense, deep spongiofibrosis (i.e. straddle injuries) can be managed with internal urethrotomy, with a 74% moderately long-term success rate.” • Internal urethrotomy refers to any procedure that opens ...
Surgery
null
1bff6b22-ba6d-44f2-89a6-65638ba21b7b
Passavant ridge is formed by:
Tensor veli palati and superior constrictor
Palatopharyngeus and superior constrictor
Palatopharyngeus and inferior constrictor
Palatoglossus and superior constrictor
1b
single
Some fibres of the palatopharyngeus muscle (arising from palatine aponeurosis) sweep horizontally backwards and join the upper fibres of the superior constrictor muscle to form a U-shaped muscle-loop in the posterior pharyngeal wall underneath the mucosa, which is pulled forward during swallowing to form the Passavant ...
Anatomy
null
be570a13-ec95-4cbf-a0da-9931f2567a4e
Which of the following structures develops from all the three germ layers?
Soft Palate
Mitral valve
Tympanic membrane
Tooth
2c
multi
null
Anatomy
null
0a5ca683-cbae-451a-b6cc-4f6c6a3aedb5
An 8-yr old boy presents witha gadually progessing swelling and pain since 6 months over the upper tibia. On X-ray there is alytic lesion with scleotic margins in the upper tibial metaphysis. The diagnosis is
Osteogenic carcinoma
Osteoclastoma
Brodie's abscess
Ewing's sarcoma
2c
multi
Lytic lesions with sclerotic margins in the upper end of tibia in an 8 yr old boy suggests the diagnosis of Brodie&;s abscess. lytic lesions with sclerotic margins are seen in: simple bone cyst brodie&;s abscess osteoblastoma chondroblastoma. ref : maheswari 9th ed
Anatomy
Skeletal infections
300cb9b0-312f-4b8a-90c9-f3041dacaae1
Treatment of paracetamol toxicity is
Alkaline diuresis
Hemoperfiision
Dialysis
N - acetyl cysteine
3d
single
Ans. is 'd' i.e., N - acetyl cysteine Paracetamol poisoning* It is a potent hepatic toxin. A small part is converted by a liver enzyme into N - acetyl-p-benzoquinoneimine.* Glutathione and other sulphydryl compounds detoxify this substance, but in overdose NABP accumulates and causes severe centrilobular liver necrosis...
Forensic Medicine
Toxicology
b8ec0b81-230f-40e1-b585-55a30bdd78ca
Laryngospasm under anaesthesia can be relieved by:
Aminophylline
Salbutamol
Terbutaline
Succinylcholine
3d
single
Suxamethonium is depolarizing relaxant, used to revert the spasm under anaesthesia.
Unknown
null
641510f7-93f1-40a0-bd0c-9d6044f47f0a
Bisecting angle technique is based upon?
Mara principle
SLOB rule
Rule of isometry
Convergence
2c
single
The bisecting-angle technique is based on a simple geometric theorem, Cieszynski’s rule of isometry, which states that two triangles are equal when they share one complete side and have two equal angles. Dental radiography applies the theorem as follows. The receptor is positioned as close as possible to the lingual su...
Radiology
null
2f1cce80-9fe2-4c5f-a5b4-d4a2f46f33cb
Postpaum tubectomy in a hea disease patient is done at
48 hours
1 week
2 weeks
Immediately
1b
single
Sterilization should be considered with the completion of the family at the end of first week in the puerperium under local anaesthesia throught abdominal route by minilap technique. If the hea is not well compensated the husband advised for vasectomy.
Gynaecology & Obstetrics
Medical, surgical and gynaecological illness complicating pregnancy
6819e3f3-6aed-4979-b434-04f594904d40
Liver synthesises all except
C3 complement component
Haptoglobin
Fibrinogen
Immunoglobulin
3d
multi
Immunoglobulins are synthesized by the B-lymphocytes.
Physiology
Gastrointestinal System
f414fef7-dc13-4a20-b880-51185526dd37
Hereditory spherocytosis is due to deficiency of-
Ankyrin
Actin
Selectin
Integrin
0a
single
HS is caused by diverse mutations that lead to an insufficiency of membrane skeletal components. The pathogenic mutations most commonly affects ankyrin, band 3, spectrin, or band 4.2. Ref :Robbins pathologic basis of disease ; south east asia edition ;pg:633
Pathology
Haematology
9ee8fa23-f62d-4493-993e-6526d68fa6da
How many incisions are used in the divided system approach of pars planavitrectomy?
1
2
3
4
2c
single
It has the advantage of smaller instruments,easy handling,improved visualisation REF:khurana,pg no 261
Ophthalmology
Miscellaneous
cc8de638-acd6-4011-9a54-2969fcc35f87
Commonest dislocation of elbow -
Anterior
Posterior
Both same
Medial
1b
multi
Ans. is 'b' i.e.. Posterior o The elbow dislocation is nearly always poserior or posterolateral.o In posterior elbow dislocation, elbow is flexed with exaggerated prominence of the olecranon.Dislocation of elbowo Dislocation of the elbow is usually caused by a heavy fall onto the outstretched hand.o The dislocation is ...
Orthopaedics
Dislocation of Elbow Joint
166c68fd-6d20-47a8-85c1-dafacc2dcae1
Branching posterior spoke like cataracts (Propeller) are seen in:
Down's syndrome
Fabry's disease
Neuro fibromatosis
Atopic keratoconjunctivitis
1b
single
Ans. Fabry's disease
Ophthalmology
null
1faab49d-83a7-48fd-bef4-e4dc6a19f831
All of the following drugs are non-selective Beta blockers EXCEPT:
Propanolol
Timolol
Sotalol
Carvedilol
3d
multi
Non-selective beta blocker are propranolol, sotalol, timolol. Non-selective beta blockers with additional alpha blocking propey are labetalol and carvedilol. From essential of medical pharmacology K D Tripati 7th edition page no 144
Pharmacology
Autonomic nervous system
e38db850-66e2-4705-9368-04d84aa8247a
which of the following SNRI used in the management of stress urinary incontinence
brofromine
citalopram
nefazodone
duloxetine
3d
single
SNRI * IMPOANCE Dual antidepressant like TCA but better than TCA has it has no dryness of mouth, hypotension, sedation * MECHANISM Inhibits the reuptake of both serotonin and dopamine * DRUGS VENLEFEXINE DESVENLEFEXINE DULOXETINE * USE Duloxetine===PAIN ASSOSIATED WITH DIABTIC NEUROPATHY and STRESS URINARY INCONTINENCE...
Psychiatry
Pharmacotherapy in psychiatry