text stringlengths 1 27.3k | meta dict |
|---|---|
{#sp1 .418}
| {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
*Candida* vulvovaginal infection is a frequent and common distressing disease affecting 70%--75% of women of childbearing age worldwide at least once during their lifetime. 5%--10% of women with a primary episode of VVC subsequently experience frustrating recurrent infection (RVVC) [@po... | {
"pile_set_name": "PubMed Central"
} |
Data underlying the study cannot be made publicly available due to legal and ethical considerations. European Union (GDPR) and French (Law n°78-17 of 6 January 1978) laws restrict the public sharing of personally identifiable data. Requests for data will be processed according to the French MR-003 Code of conduct by th... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and its Supporting Information files.
Introduction {#sec001}
============
Gastric cancer is the fourth most common cancer and the second leading cause of cancer related death in the world \[[@pone.0128751.ref001]\]. Its morbidity and mortality is particularly pronounced in Asian... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
Human embryonic stem cells (hESCs) can be maintained in culture in a self-renewing state and differentiate into all three embryonic germ layers. Although they hold great promise for regenerative medicine, hESC-based therapy faces several challenges. Concerns have been raised regardi... | {
"pile_set_name": "PubMed Central"
} |
Many endocrinologists thrive on the expansive nature of endocrine disease. However, sometimes it feels like clinical endocrinology is dominated by diabetes. Understandably, since diabetes is arguably the most common endocrine disease, certainly time-consuming and expensive, and apparently at no risk of abating. This is... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and in supporting information files. DNA sequences have been deposited at DDBJ/EMBL/GenBank under the accession LNFW00000000.
Introduction {#sec001}
============
*Cochliobolus miyabeanus* ((Ito & Kuribayashi) Drechsler ex Datur.) (anamorph = *Bipolaris oryzae* (Breda de Haan) Sh... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
Ethylene glycol monomethyl ether (2-methoxyethanol \[2-ME\]) regarded as a potent occupational toxin and its toxicological manifestations are well known in humans. The main sources of 2-ME toxicity are of industrial products, including paints, inks, hydraulic fluids, and jet fuels.\... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec0005}
============
Chronic inflammatory disorders, including psoriasis, are characterized by enhanced atherosclerosis and consequently higher cardiovascular morbidity and mortality rates compared with the general population.[@bib0005], [@bib0010], [@bib0015], [@bib0020]
Therefore, particular attenti... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1-1}
============
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease\[[@ref1]\]. RA can cause joint pain, deformation, and even disability, having a serious impact on the quality of life of patients. At present, it is still not clear what the etiology of RA is, but most scholars think... | {
"pile_set_name": "PubMed Central"
} |
1.. Introduction {#sec1}
================
*Streptococcus pneumoniae* is a major human pathogen that is responsible for respiratory-tract infections, septicaemia, otitis media and meningitis. Current broad-spectrum antibiotic treatments for *S. pneumoniae* are increasingly unsuccessful owing to the emergence of drug-re... | {
"pile_set_name": "PubMed Central"
} |
###### Key messages
What is already known about this subject?
=========================================
- Previous studies suggest that the early stages of rheumatoid arthritis (RA) may offer a therapeutic window of opportunity during which it may be possible to prevent joint damage.
- In methotrexate (MTX)-naiv... | {
"pile_set_name": "PubMed Central"
} |
**CDC Adoption of ACIP Recommendations**
Recommendations for the routine use of vaccines in children, adolescents, and adults are developed by the Advisory Committee on Immunization Practices (ACIP). ACIP is chartered as a federal advisory committee to provide expert external advice and guidance to the Director of CDC... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
A correct interpretation of the direction of evolution in basal parts of the mammalian tree has important implications for different aspects of biology and also for medicine (e.g., the selection of appropriate model organisms). However, some basal relationships may still need further ex... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Almost half of the patients suffering from a major depressive episode (MDE) fail to achieve a response, despite sequential combination or augmentation treatment strategies, irrespective of the operational definition adopted for treatment-resistant depression (TRD) ([@B1], [@B2]). The ra... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Graphene is a monolayer of sp^2^-bonded carbon atoms, and this sp^2^ bond makes the graphene structure look like honeycomb crystal, as shown in Figure [1](#F1){ref-type="fig"}\[[@B1]\]. Graphene is called the mother of graphite (many layers of graphene) because it can act as the basic building bl... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-ijms-18-02624}
===============
Nitrogen (N) is a fundamental constituent of many cell components such as amino acids, proteins, cell walls, membranes and nucleic acids. Nitrogen deficiency reduces plant growth and development, photosynthesis, leaf area, and ultimately limits plant productivity \... | {
"pile_set_name": "PubMed Central"
} |
Photosynthesis is a vital process for plant development and survival which is precisely regulated at several genetic, molecular and physiological levels during the plant growth cycle[@b1]. Photosynthetic pigments (chlorophylls and carotenoids) are a group of molecules that belong to a large class of compounds of differ... | {
"pile_set_name": "PubMed Central"
} |
Jean-Paul Iyombe-Engembe, Dominique L Ouellet, Xavier Barbeau, Joël Rousseau, Pierre Chapdelaine, Patrick Lagüe and Jacques P Tremblay
*Molecular Therapy---Nucleic Acids* (2016) **5**: e283; doi:[10.1038/mtna.2015.58](/doifinder/10.1038/mtna.2015.58)
Following publication, the authors noted that in several instances ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S0001}
============
Colorectal cancer (CRC) is the second most common cancer in women and the most common cancer in men worldwide.[@CIT0001] With changes in life styles and nutritional habits, the incidence and mortality rates of CRC in China have increased gradually in recent years.[@CIT0002] The effec... | {
"pile_set_name": "PubMed Central"
} |
Case Report
===========
Numerous cases of sudden deaths caused by intentional propane and/or butane inhalation have been described in the existing literature,[@b1-ndt-11-1157],[@b2-ndt-11-1157] but cases of survivors, with relative descriptions of the associated consequences, are very rare. We report a patient who sur... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Compared to ST elevation myocardial infarction (STEMI), unstable angina and non-ST elevation myocardial infarction (UA/NSTEMI) show lower early mortality, but the long-term prognosis of these conditions is known to be worse ([@B1]-[@B5]). As the patients with UA/NSTEMI tend to be older and ha... | {
"pile_set_name": "PubMed Central"
} |
{.330}
{.331}
| {
"pile_set_name": "PubMed Central"
} |
{#Fa}
Preventing Chronic Disease (PCD) recognizes that public health and clinical interventions are often collaborative, multifaceted, multicomponent, and multisite with diverse participants, stakeholders, and partnerships ([@R1]). As such, evaluation of these efforts canno... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-ijerph-17-05944}
===============
Adolescent mental health problems are common and linked to premature death and serious dysfunction in adulthood \[[@B1-ijerph-17-05944]\]. Approximately 10% to 20% of adolescents worldwide suffer from mental health problems, and such problems have become the lead... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec0005}
===============
Neurocysticercosis (NCC) caused by the larval stage of the pig tapeworm *Taenia solium* is a serious neurological disease ([@bib0130]). In humans, epilepsy, headache and impaired vision are common clinical presentations of NCC and leading causes of morbidity. Dementia, learni... | {
"pile_set_name": "PubMed Central"
} |
Citation {#SECID0EOGAC}
========
Costa DNR, Mathis WN, Marinoni L (2016) A revision of the shore-fly genus *Lamproclasiopa* Hendel (Diptera, Ephydridae). ZooKeys 631: 1--99. doi: [10.3897/zookeys.631.10718](10.3897/zookeys.631.10718)
Introduction {#SECID0E2GAC}
============
The need for revision of *Lamproclasiopa* ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
As an integrated component of computerized and flexible manufacturing systems, the Job-Shop Scheduling Problem (JSP) is encountered in many industrial contexts. The importance of this problem is two-fold. First, it has a wide-spread applicability in manufacturing, and second, despite ... | {
"pile_set_name": "PubMed Central"
} |
Data are available from Oregon State University <ScholarsArchive@OSU> (<https://ir.library.oregonstate.edu/concern/datasets/8623j475z>).
Introduction {#sec001}
============
The genus *Alkanna* belongs to family Boraginaceae, subfamily Boraginoidae, tribe Lithospermeae \[[@pone.0233516.ref001]\]. The *Alkanna* species... | {
"pile_set_name": "PubMed Central"
} |
1.. Introduction
================
Traumatic brain injury (TBI) triggers a cascade of changes inducing the development of secondary brain damage with nitric oxide (NO) playing an important role. NO is a strong vasodilator and regulates cerebrovascular tone and perfusion \[[@b1-ijms-15-04088]\]. Therefore, it is not sur... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#s0005}
===============
The development of appropriate patient selection criteria for tumor specific treatment including chemo- and radiotherapy (RT) is the cornerstone of modern precision oncology. With regard to life-threatening conditions such as brain-disseminated cancer it is widely believed and ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Chronic obstructive pulmonary disease (COPD) and tuberculosis (TB) are both diseases that mainly affect the lungs and are major causes of morbidity and mortality worldwide.
One third of the world population is infected with *Mycobacterium tuberculosis* and eight million new cases of TB... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and its Supporting Information files.
Introduction {#sec001}
============
*Brassica oleracea* is an important vegetable crop and is genetically diverse, having various subspecies, such as cabbage, cauliflower, broccoli, kale and wild-type, and having many known useful traits, su... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Myofascial Pain Syndrome (MPS) is exceedingly common in Western society \[[@B1]-[@B3]\]. Vernon and Schneider note that MPS is thought to be the leading diagnosis among pain management specialists \[[@B4],[@B5]\] and the leading diagnosis in pain patients reporting to general practitioners \[... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Leptospirosis is a zoonotic infectious disease caused by bacteria of the genus *Leptospira* that affects domestic and wild animals. The disease is distributed worldwide and of great public health importance, especially in warm and humid climates. The bacterium is shed in the urine of infe... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Achalasia is a rare esophageal motility disorder involving the smooth muscle layer of the esophagus and the lower esophageal sphincter (LES). It is characterized by incomplete LES relaxation, increased LES tone, and nonperistaltic contractions of the esophageal body. The main sy... | {
"pile_set_name": "PubMed Central"
} |
1.. Introduction
================
Human segmentation in uncontrolled environments is a hard task because of the constant changes produced in natural scenes: illumination changes, moving objects, changes in the point of view, occlusions, just to mention a few. Because of the nature of the problem, a common way to proce... | {
"pile_set_name": "PubMed Central"
} |
Approximately 20% of women experience an episode of major depression, a rate that is twice that of men.^[@ref1]^ The period of greatest vulnerability for women appears to be the childbearing years, with the initial onset of depression most likely to occur between the ages of 25 and 44.^[@ref2]^ Several forms of depress... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Primary bone lymphoma (PBL) is defined as lymphoma localized to the bone without evidence of involvement of lymph nodes or other tissues at presentation. It one of the rarest primary bone malignancies, accounting for less than 5% of all primary bone tumors \[[@ref1]\]. PBL constitutes less th... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Colorectal cancer (CRC) was the third most common cancer and the third most common cause of cancer-associated mortality in 2019 in the USA ([@b1-ijmm-46-04-1525]). Patients with stage I and II CRC who undergo colectomy, proctectomy or proctocolectomy often receive neoadjuvant radiation or che... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Left ventricular non-compaction (LVNC) is an unclassified cardiomyopathy and there is no consensus in the diagnosis of LVNC. The aims of this study were to establish quantitative method to diagnose isolated LVNC (INC) using cardiac magnetic resonance (CMR) imaging and to suggest novel qualitative... | {
"pile_set_name": "PubMed Central"
} |
Cholelithiasis is a major public health problem in developed countries, affecting up to 20% of the population. [@JR1800087cr-1] Cholelithiasis is responsible for 90 to 95% of cases of acute cholecystitis, and 2% of patients with nonsevere cholecystitis experience recurrence within 8 to 10 weeks. [@JR1800087cr-2] Cholec... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
A unique feature of the space radiation environment is the presence of galactic cosmic rays (GCRs) and solar particle events (SPEs). GCR involves protons and fully ionized atomic nuclei such as ^56^Fe, while SPE includes predominantly low-to-medium energy protons with a small heavy ion compon... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
RNA interference (RNAi) is a highly conserved biological phenomenon in all eukaryotes, including renal cells. In the late 1990s, due to the development of molecular biology and genetics, the biological understanding of RNA evolved from simply an intermediate between DNA and protein to... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
The malignant nature of circulating tumor cells (CTCs) has been recently demonstrated using xenograft models \[[@CR1], [@CR2]\], and it is widely accepted that these cells are responsible for tumor metastasis. CTCs have been detected in several tumor types, including breast, prostate, col... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
The chemoselective reduction of organic compounds is one of the most fundamental reactions in organic chemistry. Among these reductive reactions, the deoxygenation of epoxides into alkenes ([Scheme 1](#molecules-16-08209-f006){ref-type="scheme"}) has attracted much attention in both org... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-molecules-25-01922}
===============
Metabolic syndrome is a clustering of known cardiovascular risk factors including obesity, hyperglycemia, insulin resistance, dyslipidemia, and hypertension \[[@B1-molecules-25-01922],[@B2-molecules-25-01922]\]. There is a strong relationship between insulin r... | {
"pile_set_name": "PubMed Central"
} |
Dear Editor
I wish to thank Dr. Enrico Pisoni and Dr. Rita Van Dingenen for their effort to write comments on my recent paper "*Assessing nitrogen dioxide* (*NO* ~*2*~) *levels as a contributing factor to coronavirus* (*COVID-19*) *fatality*" ([@bb0005]). I will answer all their comments as they appear in the letter t... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
Parkinson's disease (PD) is a common neurodegenerative disease in the aging population. PD is characterized by the selective death of dopaminergic neurons in the substantia nigra leading to low levels of dopamine in the striatum \[[@B1-ijms-15-13388]\]. The etiology of PD is still elusi... | {
"pile_set_name": "PubMed Central"
} |
Image in medicine {#sec1}
=================
A 40-year-old woman, without medical or surgical history, presented in our department for a gradually enlarged mass exteriorized from vagina (figure A). There was no history of vaginal discharge, lower abdominal pain or urinary complaints. On speculum examination, a peduncul... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
As occurs with other chronic inflammatory conditions, ankylosing spondylitis (AS) is associated with a process of accelerated atherosclerosis \[[@CR1], [@CR2]\] which leads to increased rates of subclinical atherosclerosis \[[@CR3]\] and cardiovascular (CV) events \[[@CR4]\]. A recent met... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Nowadays, many of pathogenesis of diseases have been determined \[[@B32]--[@B34]\]. Methylation in the 5′ cytosine in the CpG dinucleotides is crucial a mechanism that regulates gene expression without changing DNA sequence and can be inherited to the offspring \[[@B1]\]. The pr... | {
"pile_set_name": "PubMed Central"
} |
Rheumatoid arthritis (RA) is a systemic autoimmune disorder involving chronic inflammation. RA is characterized by an excessive inflammatory response and deforming polyarthritis, activation of T cells. Interleukin (IL)-17 produced by T helper (Th) 17 cells increases in the peripheral blood of patients with RA[@b1]. Add... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
The potential importance of translational research for autism spectrum disorder (ASD) is increasing given that its biological pathology and fully effective treatments have not yet been determined. Specifically, the acquisition of more knowledge about objective and quantitative neurobiol... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-sensors-18-00116}
===============
Surface plasmon polaritons (SPPs) are electromagnetic fields propagating along the interface of metal-insulator, and have been widely discussed for several decades due to the ability to modulate light in nanoscale, as well as break the diffraction limit \[[@B1-s... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-cells-09-01451}
===============
Cancer, a significant and serious medical issue, is driving mortality throughout the globe \[[@B1-cells-09-01451]\]. It is distinguished by uncontrolled and unscheduled cell multiplication. Tumors associated with viral or bacterial infection and genetic mutations ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
The regulation of immune responses by the nervous system represents a spectrum of inhibitory and excitatory neural pathways. Inflammatory reflexes are fundamental neural circuits mediated by the vagus nerve and are important for immune response resolution, as they prevent excessive cy... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .370}
| {
"pile_set_name": "PubMed Central"
} |
Introduction {#ss1}
============
Precipitation of second phase particles such as Ti, Nb, and V carbonitrides can have a very positive effect on mechanical properties of microalloyed steels. Low temperature precipitation (in ferrite or in α/γ interphase) leads to a distribution of fine particles, that have a strong str... | {
"pile_set_name": "PubMed Central"
} |
Identifying a small number of variants most likely to be causal in a specific genetic region (such as a gene) is a challenging problem, but of fundamental importance to the understanding of precise biological mechanisms that influence disease (MacArthur et al., [@B12]). Rare causal variants, by definition, are only see... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
According to World Health Organization (WHO) estimates, about 303,000 maternal deaths occurred in the world in 2015. Of these deaths, 66% occurred in sub-Saharan Africa followed by Southern Asia at 22%. About 99% of the maternal deaths occurred in low and middle income countries and most ... | {
"pile_set_name": "PubMed Central"
} |
1.. Introduction {#sec1}
==================
The history of search--match in the crystallographic context coincides with the history of Hanawalt's work and the International Center for Diffraction Data (ICDD), and a good account of those early days is given in the paper by Hanawalt (1986[@bb16]).
Following the 'Hana... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S1}
============
Rupture of vulnerable atherosclerotic plaques is the leading cause of stroke and myocardial infarction ([@B10]). These serious accidents often occur when plaques in the arteries suddenly rupture, causing thrombus and leading to the obstruction of the blood flow to the brain or the heart... | {
"pile_set_name": "PubMed Central"
} |
With improvement in resolution broad use of the multi-detector row CT (MDCT), has resulted in detection of an increased number of small pulmonary nodules ([@B1]). Although a majority of small pulmonary nodules are benign ([@B2]-[@B5]), a specific diagnosis for a nodule frequently remains undetermined. Diagnostic evalua... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
In experimental settings, scores that predict risk for clinical deterioration in hospitalised patients have evolved from vital sign based Early Warning Scores (EWS) to systems that utilise the large amount of patient centred data in Electronic Patient Records (EPRs) \[[@CR1]--[@CR4]\]. Th... | {
"pile_set_name": "PubMed Central"
} |
Almost all electronic (<http://www.itrs.net/>) and spintronic devices[@b1] have junctions between different types of semiconductors (for example, p--n junctions) and metals and non-metals (for example, metal/semiconductor and tunnel junctions) at the core of their functionality. The efficiency and even the actual funct... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Captive wildlife programs harbor animals in fenced areas, which can allow parasite infection and re-infection to easily occur. Pasture rotation is not feasible in these programs and therefore, re-infection is often high. Several programs utilize anthelmintics to control parasite... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
The usage of implantable central venous ports has increased year by year because of progress in chemotherapy, leading to increased numbers of patients who receive long-term treatment, and because repeated administration of continuous intravenous infusions make it difficult to ob... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
In recent years, ultrasound diffraction tomography (UDT) has drawn more and more attention in medical imaging field. Different from traditional B-mode ultrasound technique which displays the strength of the echoes with gray scale to show anatomic structure, UDT infers the distri... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1}
============
Gene therapy treats disease by using genetic material to change or correct gene expression to cure disease. The concept of gene therapy emerged in the early 1970s as a consequence of both increased understanding of the role of genes in human disease and the development of genetic engi... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .120}
{#sp2 .121}
{#f1 .120}
{#f2 .121}
| {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1}
============
Antisocial behavior is mostly regarded as consisting of attitudes that go against the grain in society and/or disregard the rights of others ([@ref20]). Antisocial behavior can be harmful to others or their homes and possessions. Adolescents, their family and society can be burdened w... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Sterile alpha motif and HD domain-containing protein 1 (SAMHD1) is an important regulator of cellular 2′-deoxynucleoside-5′-triphosphate (dNTP) in mammalian cells^[@CR1]^. SAMHD1 is widely expressed in most tissue types^[@CR2],[@CR3]^ and catalyses the hydrolysis of dNTPs into their c... | {
"pile_set_name": "PubMed Central"
} |
The electronic version of this article is the complete one and can be found at: <http://f1000.com/prime/reports/m/6/101.1>
Commentary on: Recent advances in understanding/management of hypospadias \[F1000Prime Reports, 2014\] {#s01}
======================================================================================... | {
"pile_set_name": "PubMed Central"
} |
TERMS AND DEFINITIONS {#S0001}
=====================
*Chaos theory* is a set of concepts which studies the behaviour of dynamical systems that are highly sensitive to initial conditions.
*Deduction*. A form of reasoning which works from the more general to the more specific. Deduction is a tool for rigorously testing... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#s0005}
===============
Parkinson\'s disease (PD) is a neurodegenerative condition that clinically manifests with abnormalities in movement, olfactory senses, gastrointestinal function and an overall decline in cognitive abilities as the disease progresses. These symptoms are associated with the progr... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Intussusception is a common surgical emergency in infants and children. The incidence of intussusception is approximately one to four per 2,000 infants and children.[@b1-tcrm-11-1837] The diagnosis of intussusception was confirmed by clinical and radiological findings. Common signs and sympto... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
Malignancy of the thyroid gland is the most common in the endocrine system and has been identified into different subtypes depending on the cells or growth pattern.\[[@ref1][@ref2]\] Papillary thyroid carcinoma (PTC), a well-differentiated tumor, is the most common histological subt... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Cell cycle arrest is a key mechanism that is activated by cellular stress, and is strictly controlled by many regulatory mechanisms that either permit or restrain its progression ([@b1-or-38-01-0031]). The regulatory factors controlling cell cycle progression are cyclins, cyclin-dependent kin... | {
"pile_set_name": "PubMed Central"
} |
To the editor {#S1}
=============
The proceedings of a recent meeting on alopecia areata (AA) ([@R4]) summarized work using the surgically induced C3H/HeJ mouse model for AA ([@R13]), in which investigators found enlarged hearts in affected mice, suggesting an association between AA and cardiac findings. However, the ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Traditional genetic approaches have played a pivotal role in establishing the requirement of individual gene activities and cell behaviors in complex morphogenetic processes^[@CR1]--[@CR9]^. More recent advances in synthetic biology are opening the possibility to engineer gene circuit... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-antioxidants-08-00004}
===============
Peroxiredoxins (Prdxs) are a widely distributed family of antioxidant enzymes that use a cysteine thiol group as a catalytic center to catalyze the reduction of hydroperoxides \[[@B1-antioxidants-08-00004]\]. These enzymes function in anti-oxidant defense a... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Epithelial ovarian cancer (EOC) is the leading cause of gynecological cancer death in the U.S. Approximately 22,000 women are diagnosed annually and 15,000 die from the disease \[[@B1]\]. Most women are diagnosed only after peritoneal dissemination has occurred. The standard treatment for patient... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .723}
{#sp2 .724}
| {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Hepatocellular carcinoma (HCC) is the sixth most common diagnosed cancer and the third leading cause of cancer death in the world \[[@CR1], [@CR2]\]. Although advances in treatment have been made in HCC in the past decades, surgical resection and liver transplantation are the primary ... | {
"pile_set_name": "PubMed Central"
} |
The content published in Cureus is the result of clinical experience and/or research by independent individuals or organizations. Cureus is not responsible for the scientific accuracy or reliability of data or conclusions published herein. All content published within Cureus is intended only for educational, research a... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Programs teaching mindful awareness to promote well-being have become a recent topic of inquiry among researchers \[[@B1]\]. Rooted in Buddhist traditions and formally developed by Jon Kabat-Zinn in the 1980s, mindfulness has developed secularly to describe a process of becoming aware of present ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Argyrophilic grain disease (AGD) is a neurodegenerative condition associated with old age and characterized by the presence of abundant small spindle 4 to 8 μm argyrophilic inclusions (argyrophilic grains) in neurons of the amygdala, entorhinal cortex, hippocampus, and other limbic brain regi... | {
"pile_set_name": "PubMed Central"
} |
As of April 12, 2020, the Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome (SARS)--CoV-2 virus has affected more than 550,000 Americans, and claimed more than 21,000 lives.[@bib1] ^,^ [@bib2] In just 2 months, the number of deaths is projected to reach over 60,000 --- despite current... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-ijerph-17-02376}
===============
Since the reform and opening up in 1978, China's economy has developed rapidly, people consume a variety of food items, and they are using more meat and dairy products. At the same time, especially after China's accession to the World Trade Organization (WTO) in ... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
============
Primary central nervous system (CNS) lymphoma is a rare type of malignancy confined to the brain, spinal cord, meninges, and orbits. Most of primary CNS lymphoma is histologically classified as diffuse large B-cell lymphoma, which has a fast growing and aggressive feature. Likewise, pri... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Increasing number of women with HIV are choosing to become pregnant as there is reduction in vertical transmission. However, management of HIV in pregnancy still poses a variety of challenges and adverse pregnancy outcomes are still common. We aimed to explore the factors associated with adverse ... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .100}
{#f1 .100}
| {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Microbial communities are known to establish sophisticated metabolic interactions in order to achieve complex and energy-expensive tasks \[[@CR1]--[@CR5]\]. These syntrophic relationships are frequently studied in bacterial pathogens and symbiotic bacteria, where the interaction with the ... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .139}
{#sp2 .140}
{#sp3 .141}
{#sp4 .142}
{#sp5 .143}
| {
"pile_set_name": "PubMed Central"
} |
{#sp1 .353}
{#sp2 .354}
{#sp3 .355}
{#sp4 .356}
{#sp5 .357}
{#sp6 .358}
{#sp7 .359}
{#sp8 .360}
![](medchirrev76... | {
"pile_set_name": "PubMed Central"
} |
Although tremendous strides have been made in total joint arthroplasty for the knee and hip, this modality is still evolving in the ankle.[@B1]-[@B3] Some of the problems that increase the difficulty in total ankle replacement (TAR) include a high prevalence of post-traumatic arthritis rather than chronic arthritis tha... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
============
The p53 tumour suppressor protein is a transcription factor that activates genes responsible for acute radiation-induced death, cell cycle checkpoint function, induction of apoptosis and senescence and tumour suppression. Its inactivation is considered a key event in human carcinogenesi... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .385}
{#sp2 .386}
| {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Parkinson's disease (PD) is the second most common age-related neurodegenerative disorder following Alzheimer's disease. The main pathological feature of PD is the progressive loss of dopaminergic neurons in the Substantia Nigra pars compacta (SNpc), with the subsequent loss of dopami... | {
"pile_set_name": "PubMed Central"
} |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.