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INTRODUCTION {#sec1}
============
*Chlamydia trachomatis* and HSV-2 are the leading sexually transmitted pathogens in the world causing 101 million and 23.6 million new cases per year, respectively (Looker, Garnett and Schmid [@bib17]; World Health Organization [@bib34]). *Chlamydia trachomatis* genital tract infectio... | {
"pile_set_name": "PubMed Central"
} |
Critical illness only happens in 5% [@bib0001] overall and in 22% [@bib0002] hospitalized COVID-19 patients, but represents the major medical resources consumer for this disease. It includes patients with respiratory failure that requires mechanical ventilation, or the ones with shock and other organ failure that requi... | {
"pile_set_name": "PubMed Central"
} |
Published: April 2, 2020
Introduction {#sec1}
============
Neurofibromatosis 1 (NF1; OMIM [162200](162200){#interref15}) is a neurogenetic condition characterized by remarkable phenotypic variability, where affected children develop a wide variety of central nervous system (CNS) pathologies, ranging from brain tumors... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Path planning is one of the important research issues in mobile robot. When executing a task, the robot is supposed to plan optimal or feasible paths to avoid obstacles in its way and to minimize cost such as time, energy, and distance. Accordingly, path planning can be regarded... | {
"pile_set_name": "PubMed Central"
} |
*Pasteuria penetrans* has potential for its development as a biological control agent of economically important root knot nematodes ([@b40-ppj-35-051]). These hyperparasites start their infection by adhering to the cuticle of infective juveniles (J2s), then penetrate the body wall to enter the host root, usually after ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Invasive fungal infections are a growing problem in our severely immunocompromised patients. Hematopoietic cell and solid organ transplantations continue to increase, and despite recent development of more active and less toxic antifungal agents, mortality rates from invasive fungal infection... | {
"pile_set_name": "PubMed Central"
} |
AT
: adenine and thymine
bp
: base pairs
CNE
: constructive neutral evolution
DAPI
: 4′,6‐diamidino‐2‐phenylindole
GC
: guanine and cytosine
gRNA
: guide RNA
kDNA
: kinetoplast DNA
mtDNA
: mitochondrial DNA
INTRODUCTION {#iub1894-sec-0001}
============
Mitochondrial genomes come in all ... | {
"pile_set_name": "PubMed Central"
} |
Porter et al. ([@B4]) recently published an interesting paper in which they explored the *in vivo* effect of the sympathetic nervous system (SNS) on cardiac electrophysiological stability. In their study, heart failure (HF) patients treated by cardiac resynchronization therapy (CRT) increased their sympathetic tone by ... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .72}
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"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-sensors-19-02335}
===============
Intrusion detection is a dynamic process of monitoring whether there exists any entity breaking into a given area, then making alarms if necessary. It gains more and more attention and has great potential in many applications, such as border protection \[[@B1-se... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Budd-Chiari syndrome (BCS) is the occlusion of major hepatic veins (HV) and retro-hepatic inferior vena cava (IVC) \[[@B1], [@B2]\]. In this rare clinical condition, IVC replacement and orthotopic liver transplantation (deceased donor or living donor) have been shown to successfully treat the... | {
"pile_set_name": "PubMed Central"
} |
1. Background {#sec1-1}
=============
Misdiagnosis is an incorrect diagnosis. The objectives of making a diagnosis are to determine the nature of a disease and to select targeted treatment so that the condition takes a favorable turn. Therefore, the incorrect, incomprehensive, or untimely diagnosis is considered to be... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
The p53 tumor suppressor protein is a latent transcription factor that increases genomic stability and protects against malignant transformations ([@b2-molce-42-773]). p53 is usually present at low levels in cells under normal conditions due to MDM2 (murine double minute 2, also used intercha... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Gas6 is a vitamin K-dependent protein, which was initially described as a protein expressed during growth arrest \[[@B1]\]. It is structurally related to the anticoagulant protein S, the two proteins having 44% amino acid identity \[[@B2]\]. Both Gas6 and protein S bind the TAM family of tyro... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Most of the estimated 50,000 youth with autism who turn 18 every year are capable of employment and have valuable contributions to make in the workforce and in their communities. Employment allows people to earn wages, increases independence, and improves quality of life (García-Villa... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Accurate and rapid testing of patients for influenza virus is important to optimize antiviral use, minimize antibiotic use, and appropriately isolate hospitalized patients to prevent hospital-acquired infections. During the 2009 H1N1 pandemic, viral culture and real-time reverse transcr... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Multiple ipsilateral renal tumors (MIRTs) are characterized as at least two tumor foci in the same kidney, separated by normal tissue \[[@CR1], [@CR2]\]. The exact incidence of MIRTs was currently unreported. According to the available related data, we conservatively estimated the inciden... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s001}
============
The cornea is a thin, transparent dome-shaped avascular tissue that is densely innervated by sensory nerve endings.^[@B1],[@B2]^ Damage to these nerve endings, resulting from surgery, trauma, neurological disease, or infection, may develop into corneal neuropathic pain (CNP).^[@B2]^ C... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
Hospital performance measurement seeks to identify and remediate low-quality care. However, because patients are not randomly allocated to hospitals, cross-hospital comparisons are limited by differences in patient case-mix and illness severity. The US Center for Medicare and Medicaid S... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s0005}
============
There is growing evidence that, in addition to brain activity that is evoked by an event, brain activity patterns that precede the onset of an event can contribute to memory performance. Several functional magnetic resonance imaging (fMRI) and magneto-/electroencephalography (M/EEG) ... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and its Supporting Information files.
Introduction {#sec001}
============
Tannic acid (TA) is a polyphenolic compound consisting of a central glucose molecule, which hydroxyl groups are linked by ester bonds with gallic acid moieties. One molecule contains 8 to 10 moles of galli... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
============
The annual rangeland of California uniquely produces forage from late fall through spring. This winter forage is frequently grazed by yearling cattle. These cattle are typically spring-born calves that are weaned in the fall and sold to stocker operators who graze them through the winte... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Cholesterol is an important structural component of cell membranes, and a precursor to the synthesis of many bioactive molecules, including bile acids and salts, vitamin D, and steroid hormone \[[@CR1]\]. In human body, the main source of cholesterol is from Intestinal absorption, and les... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Programmed cell death (PCD) is a genetically controlled process for the removal of redundant, misplaced, or damaged cells, and is associated with common morphological and biochemical changes during the development of multicellular organisms ([@bib21]; [@bib19]; [@bib48]). PCD is also an integ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Type 2 diabetes (T2D) is a common metabolic disease of increased plasma glucose levels to which individuals are predisposed to by a combination of genes and environmental factors. The hyperglycemia typically results from decreased insulin sensitivity (insulin resistance) in insulin-de... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-polymers-08-00210}
===============
The viscosity study of polymers has been of continuing interest, mainly due to its fast measurement and importance in the characterization of the intermolecular interaction, as it describes the measure of the resistance to flow of a material, mixture, or soluti... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Sulfur (S) is an important additive for controlling the structures and properties of carbon nanotubes (CNTs). Many interesting carbon nanostructures, such as Y-junction CNTs \[[@B1]\], sea-urchin-like CNTs \[[@B2]\], long single-walled CNT (SWCNT) strands \[[@B3]\], double-walled CNT films \[... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
Introduction
============
Type 1 diabetes (T1D) is an autoimmune disorder engendered by the deleterious actions of several cell types from both the innate and the adaptive immune systems (Lehuen *et al*, [@b29]). We have recently revealed using the non-obese diabetic (NOD) mouse model that autoimmune diabetes is initi... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Pancreatic cancer is a rapidly fatal disease with a 5-year survival of around 4--6% [@R1],[@R2]. Current chemotherapy regimens have modest survival benefits. Although newer agents are being tested in pancreatic cancer patients, gemcitabine remains the first-line treatment [@R3],[@R4]. However... | {
"pile_set_name": "PubMed Central"
} |
As much of the world has gone into complete lockdown, woefully unprepared, many countries have turned to South Korea for answers, given its handling of COVID‐19. Rapid and widespread testing, expansive surveillance assemblage and selected quarantine practices are upheld by many countries and public health professionals... | {
"pile_set_name": "PubMed Central"
} |
Microbial Biotechnology (2018) 11(1),248--256
**Funding Information**
This work was partially supported by National Key Technology Research and Development Program of the Ministry of Science and Technology of China, grant number 2013BAD03B01 and the National Natural Science Foundation of China, grant number 31402078.... | {
"pile_set_name": "PubMed Central"
} |
Nano-structural color filters have been extensively researched as crucial elements for a variety of applications, such as for display/imaging devices, organic light emitting diodes, organic solar cells, etc[@b1][@b2][@b3][@b4][@b5]. These are regarded to be a promising alternative to conventional colorant pigment based... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
The metabolic syndrome (MetS) is defined as a set of interrelated risk factors of diabetes and cardiovascular diseases (CVD) \[[@B1]\]. There are some criteria for clinical diagnosis of metabolic syndrome that include elevated waist circumference (≥102 cm in men and ≥88 cm in wo... | {
"pile_set_name": "PubMed Central"
} |
1.. Introduction
================
The emergence of more multidrug resistant pathogens at an alarming rate is now a major concern to the public health care and policy makers in the medical industry. The continuous misuse of broad-spectrum antibiotics has caused bacteria to develop resistance hence leading towards a con... | {
"pile_set_name": "PubMed Central"
} |
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![](envhper00348-0069.tif ... | {
"pile_set_name": "PubMed Central"
} |
J Diabetes Investig 2017; 8: 168--173
Introduction {#jdi12574-sec-0005}
============
Gestational diabetes mellitus (GDM) is impaired glucose tolerance during pregnancy in women with normal glucose metabolism before pregnancy. The proportion of pregnant women with GDM is increasing worldwide, reportedly ranging from 1... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Skin cancer is a disease caused by the abnormal and uncontrolled proliferation of melanocytes---cells that pigment the skin---that have undergone a genetic mutation. This disease is one of the most widespread around the world as it represents 40% of all cancers \[[@CR6]\]. There are s... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency state. Affected cases are susceptible to special infections including particular fungal and bacterial disease \[[@B1], [@B2]\], most of them are diagnosed in early childhood \[[@B3]\]. Pneumonia is the most c... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Back in 1827, using an optical microscope, the botanist Robert Brown first observed the jittery motion of small suspended particles and found that each moving step of the particle was independent of the previous one ([@R1]). This random motion of the particles, now known as passive Brownian m... | {
"pile_set_name": "PubMed Central"
} |
I[NTRODUCTION]{.smallcaps} {#sec1-1}
==========================
Uterine fibroids are reported to be the common benign tumor of the uterus, with an incidence exceeding 70-80% among women.\[[@ref1]\] Although the etiology of myomas is still debated, accumulating evidence suggests that epigenetic changes may play a key r... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Syphilis has been a major cause of mortality and morbidity for around 500 years ([@B1]). The World Health Organization (WHO) estimates that 12 million new cases of syphilis occur each year ([@B50], [@B51]). In Chinese history, syphilis had been eradicated over a period in 1960s, but by the la... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
The health of women and children remain to be the major challenges in the world, particularly in developing countries. Globally an estimated 287,000 maternal deaths occur annually, 99 % of this occurs in developing countries, particularly in Sub-Saharan Africa which accounted for 56 perce... | {
"pile_set_name": "PubMed Central"
} |
Work performed at the University of Missouri and the University of Pennsylvania.
The work at the University of Pennsylvania was supported in part by grant from the NIH (OD 010939).
CBC
: complete blood count
FIO~2~
: fraction of inspired oxygen
MB
: methylene blue
methb%
: methemoglobin percentage
SpO... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-ijms-19-04082}
===============
Dentin hypersensitivity following tooth preparation and cementation of fixed partial dentures (FPDs) has been a common phenomenon \[[@B1-ijms-19-04082]\]. Post-cementation complaints from patients are received for 20 to 30% of crowns inserted \[[@B2-ijms-19-04082]\... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Until now, learning by doing has been the predominant method of training in management competencies for most practicing physicians. In the 1970s some authors proposed that physicians should not only be trained as medical experts, but also as medical managers. Lawson et al (1976) wrote: "Times and... | {
"pile_set_name": "PubMed Central"
} |
The authors confirm that all data underlying the findings are fully available without restriction. All PhyloChip data are available for download from the GreenGenes database \[<http://greengenes.lbl.gov/Download/Microarray_Data/MIAME_data_files_Wastewater-reactors_Hillson.zip>\]. All PhyloChip data were deposited in NC... | {
"pile_set_name": "PubMed Central"
} |
Data are available upon request from Maria del Mar Garcia Saiz, president of the Research Ethics Committee, Hospital Universitario de Canarias. Interested researchers can contact the committee at <ceticohuc.scs@gobiernodecanarias.org>.
Introduction {#sec009}
============
Clinical guidelines recommend more intensive s... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Esophageal cancer (EC) was the sixth leading cause of cancer-associated mortality worldwide in 2014 ([@b1-ol-0-0-11969]). Adenocarcinoma and squamous cell carcinoma are the primary types of EC ([@b2-ol-0-0-11969]). Squamous cell carcinoma is more common in Asia and developing countries ([@b3-... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Analysts have debated the benefits and harms of screening mammography in the medical literature for over a decade \[[@B1]-[@B3]\]. The 1997 National Institutes of Health Consensus Conference concluded that younger women should decide for themselves whether and when to begin screening. Physicians ... | {
"pile_set_name": "PubMed Central"
} |
Data at ages 7, 9, and 10 are freely accessible at <http://www.teds.ac.uk/SRCDdataset.html>. Due to ethical restrictions imposed by the study\'s Ethics Review Board and patient consent, the data are available upon request. Request for access to further data should be made to Professor Robert Plomin (<robert.plomin@kcl.... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Antiphospholipid syndrome (APS) is defined by two major components: the occurrence of at least one clinical feature, venous or arterial thrombosis and/or pregnancy morbidity, and the presence of at least one type of autoantibody known as an antiphospholipid antibody ((aPL), detected b... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Immunoglobulin A vasculitis (IgA) is an immune complex small vessel leukocytoclastic vasculitis that commonly affects the skin, joints, gastrointestinal (GI) tract, and kidneys \[[@CR1]\]. IgAV is a typical childhood vasculitis, commonly with a benign, self-limiting course and complet... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Hepatic ischemia-reperfusion injury (HIRI) remains a major cause of damage that is associated with several liver diseases and hepatic surgery, which affects the outcomes of hepatic operations and other liver diseases related to HIRI ([@b1-ijmm-45-06-1875],[@b2-ijmm-45-06-1875]). Complex mecha... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
As the size of the older population increases, the rate of surgical procedures in the elderly has been rising. In the USA, about 41% of the people who underwent surgery were over the age of 65 years, and similar statistics are reported from England and some developing countries \[[@CR1], ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Organisms residing in the oral cavity (oral microbiota) contribute to health and disease, and influence diseases like oral candidiasis, the most common oral complication of HIV-infection [@ppat.1003996-Jenkinson1], [@ppat.1003996-Patton1]. Pathogenesis of oral candidiasis is linked to v... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Linking legacy clinical and administrative databases provides a novel resource for investigating cancer risk factors and predictors of clinical outcomes. However, using large linked databases (LLDB) for medical research purposes is limited by several factors. First, reliance upon coded outcomes s... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Sevelamer is known as poly(allylamine) cross-linked with epichlorohydrin. Sevelamer is available in the form of hydrochloride salt as well as carbonate salt (sevelamer hydrochloride and sevelamer carbonate) and both are insoluble in water \[[@b1-scipharm.2014.82.117]\]. Sevelamer hydrochlorid... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1-1}
============
Acylation-stimulating protein (ASP) is an adipokine produced by adipocytes and generated by activation of the alternative complement pathway ([@ref1]), as well as systemically following pro-inflammatory immune activation ([@ref2]). ASP stimulates free fatty acid incorporation into a... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Buruli ulcer (BU) is the third most important mycobacterial disease in humans today, with one of the highest prevalence rates reported in southern Benin (21.5/100,000 per year), although these numbers are probably underestimated due to the focal distribution of the disease [@pntd.000201... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#section5-2050312114532809}
============
The Ryan White Comprehensive AIDS Resources Emergency (CARE) Act of 1990 established the AIDS Drug Assistance Program (ADAP). This program is the "payer of last resort" for people living with HIV (PLWH) whose income falls below a certain threshold (which varies by... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
According to the U.S. National Health Interview Survey, 13.9 percent of U.S. women reported that they smoked cigarettes in 2016^[@CR1]^, and it has been well-documented that women who smoke have greater risks for adverse reproductive health outcomes, including premature birth, deliver... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Small cell lung cancer (SCLC) accounts for \<15% of all lung cancer \[[@C1]\]. SCLC is usually initially chemotherapy (CT)-sensitive and first-line treatment is associated with high objective response rates (RRs) (45--75%). As observed in meta-analyses \[[@C2], [@C3]\], platinum derivat... | {
"pile_set_name": "PubMed Central"
} |
1.. Introduction {#s1}
================
Nest building is widespread across birds and other taxonomic groups. Wallace \[[@RSPB20152685C1]\] notwithstanding, until recently nest building by birds was considered to be innate \[[@RSPB20152685C2]--[@RSPB20152685C5]\]. An accumulation of laboratory and field data, however, ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Among the radionuclides present in radioactive wastes, there are a certain number of fission products and minor actinides. Actinides and particularly long-lived isotopes of plutonium are mainly responsible for the environmental hazard. Extensive studies during the last decades have sh... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
The importance of real-time monitoring a radial artery pressure and its waveform is steadily increased in the medical science and healthcare field. This is because the radial pulsation is a surrogate maker to estimate a central aortic pressure and its waveform which is clinicall... | {
"pile_set_name": "PubMed Central"
} |
Transmissible spongiform encephalopathies (TSEs) or prion diseases of animals include scrapie in sheep and goat, chronic wasting disease (CWD) in cervids (including mule deer, white-tailed deer, moose, elk, and reindeer), and bovine spongiform encephalopathy (BSE) in cattle; these diseases are either classical/naturall... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Human immunodeficiency virus (HIV), tuberculosis (TB), and helminthic infections are among the commonest public health problems in the sub-Saharan African countries. Micronutrient deficiencies are an additional burden for these groups of population either playing a role in their... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
With an estimated prevalence of 0.2--0.3%, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a frequent and severe chronic multisystemic disease. Patients suffer from persistent exhaustion, cognitive dysfunctions, pain and flu-like symptoms, leading to a substantial reducti... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S5}
============
Injuries are a major problem in both developing and developed countries. Trauma is a neglected public health problem in developing countries with over 90% of the world's injury deaths occurring in low- and middle-income countries.^\[[@R1]\]^ Injuries represent 12% of the global disease ... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Partial anomalous pulmonary venous connection (PAPVC) of the left pulmonary veins is significantly less frequent than right ones, and most commonly drained to the innominate vein. However, there are many patterns of anomalous draining, causing shunt from left atrium (LA) to systemic veins \[[@B1]... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Metabolic syndrome (MS) which represents a common and growing health problem in horses was first described as hypothyroidism, peripheral Cushing's disease, or pre-Cushing's syndrome \[[@CR1]\]. More recently, equine metabolic syndrome (EMS) has been linked to three key abnormalities, ... | {
"pile_set_name": "PubMed Central"
} |
Se trata de un varón de 66 años con antecedentes de insuficiencia mitral severa diagnosticada hace 4 años (con intervención quirúrgica a los 2 años del diagnóstico), con manifestación de fibrilación auricular paroxística, hipertrofia benigna de próstata, síndrome de apnea obstructiva del sueño y amaurosis fugax. Sigue ... | {
"pile_set_name": "PubMed Central"
} |
Attention Deficit / Hyperactivity Disorder (ADHD) is one of the most common problems in children and adolescents. According to the diagnostic criteria, ADHD is characterized by such symptoms as hyperactivity, attention deficit and impulsivity ([@CIT0001], [@CIT0002]). There is a high prevalence of ADHD in the family me... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Lily (*Lilium* L.) is an important bulb flower worldwide. Most lily cultivars originating from intra-sectional hybridizations of the genus *Lilium* are classified into four groups: Asiatic (A), Longiflorum (L), Oriental (O) and Trumpet (T) ([@b24-64_97]). Hybridizations within each group are ... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Since their discovery by Lee and colleagues \[[@B1]\], microRNAs (miRNAs), a class of endogenous small non-coding RNAs, are becoming increasingly recognized as crucial regulators in gene expression networks \[[@B2],[@B3]\]. They can function as translational repressors by binding to the... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Despite good financial management being an important aspect of an individual\'s success (Jorgensen, [@B22]), it is an alarming observation that people are generally poor at managing their finances (see Shapiro and Burchell, [@B44]; Ceschi et al., [@B10]). Explanations for financial mism... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
============
The secretory pathway is required for the correct modification and targeting of secretory cargoes. This pathway is composed of a series of membrane-bound compartments with varying characteristics and functions, including the endoplasmic reticulum (ER), the ER-Golgi intermediate compartm... | {
"pile_set_name": "PubMed Central"
} |
*Abbreviations used in this paper:* BZ, benzamil; CT, chorda tympani; CZP, capsazepine; ENaC, epithelial Na^+^ channel; FIR, fluorescence intensity ratio; NHE-1, Na^+^-H^+^-exchanger-1; ROI, region of interest; SBFI-AM, 4,4′-\[1,4,10-trioxa-7,13-diazacyclo-pentadecane-7,13-diylbis (5-methoxy-6,12-benzo-furandiyl\]-bist... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
The use of multiple medications (polypharmacy) by elderly patients is a significant problem in Canada. Fifty-three percent of seniors in health care institutions and 13 % living in the community surveyed take five or more medications, and this use increases with age \[[@CR1]\]. Health adm... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Mitochondria are the cellular energy-generation organelles that convert ingested food into adenosine triphosphate (ATP) using the electron transport chain. In this process, reactive oxygen species (ROS) are produced as necessary by-products and can easily lead to mitochondrial DNA damag... | {
"pile_set_name": "PubMed Central"
} |
Sir,
The report on "latex urinary catheters for the short-time drainage" is very interesting.\[[@ref1]\] Hosseinpour *et al*. concluded "urinary tract catheterization with latex catheters is a safe, feasible, and in-expensive procedure for short-term postoperative course in hypospadias surgery in patients without late... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Hemoptysis can be caused by lesions that are localized in the airway, lungs or by widespread lesions in the lungs. Diffuse alveolar hemorrhage (DAH) is characterized by widespread bleeding into the alveoli due to microvascular injury \[[@B1]\]. DAH may also be accompanied by pul... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
============
Recovery of the gait ability of stroke survivors is an important goal of rehabilitation[@r1]^)^ and is known to be influenced by environmental factors (e.g., walking on the ground, climbing stairs, and avoiding obstacles), physical factors (e.g., muscle strength, endurance, and balance)... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Pancreatic ductal adenocarcinoma (PDA) appears to develop through a series of ductal precursor lesions, including the most common type, pancreatic intraepithelial neoplasia (PanIN). Both PanINs and PDA exhibit Kras mutations, which may be an initiating event. Mouse models support this n... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S0001}
============
Liver cirrhosis is a widespread disease and a leading cause of mortality worldwide.[@CIT0001] Bacterial infection is one of the most important and serious complications in patients with cirrhosis,[@CIT0002] which is associated with a higher morbidity and mortality.[@CIT0003],[@CIT000... | {
"pile_set_name": "PubMed Central"
} |
The coronavirus disease (COVID-19) is a novel acute pneumonia caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), and the outbreak has been declared to be a pandemic by World Health Organization (WHO). SARS-CoV-2 is a single-stranded, non-segmented RNA virus with an envelope structure. After infecti... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
TAL (transcriptional activator-like) effectors (TALEs) are secreted by plant pathogenic bacteria that cause diseases in plants [@pone.0076045-Gu1]--[@pone.0076045-Boch1]. When TALEs are injected into plant cells, they enter the nucleus, bind to effector-specific sequences and manipulate... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
Fluoride has become a recurring theme in discussing water issues and particularly water quality issues in India.\[[@ref1]\] In Karnataka, where much of groundwater sources are concentrated with fluorides and nitrates, the impact is devastating. Dental and spine-related ailments are ... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-sensors-18-00107}
===============
Recently, advanced microfabrication, including complementary metal-oxide-semiconductor (CMOS) and micro-electromechanical systems (MEMS) technologies, have been enabling the fast development of various modern biomedical sensors of higher accuracy, good reliabili... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-micromachines-11-00087}
===============
There is an increasing aging population \[[@B1-micromachines-11-00087],[@B2-micromachines-11-00087],[@B3-micromachines-11-00087]\] and an increasing use of implants such as total joint replacement \[[@B2-micromachines-11-00087],[@B3-micromachines-11-00087]... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .319}
| {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Encoding unnatural amino acids (UAAs) bearing different functional groups, *via* genetic code expansion, offered the unprecedented capability for site-specific protein manipulation in living systems.^[@cit1],[@cit2]^ The introduction of chemical functionalities on a protein of interest (POI) ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
When we open a newspaper, we often encounter headlines such as "Hometown driver now a local hero" or "A lot of heroes around here." We may also come across a headline that reads "While at war, female soldiers fight to belong" (New York Times, 25 May 2015). What images of men and women do such... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Fragile X syndrome (FXS) is an inherited neurodevelopmental disorder with a wide variety of symptoms, including intellectual disability, seizures, hyperactivity, social anxiety, and others characteristic of autism spectrum disorders. It is caused by loss-of-function mutations in the RNA... | {
"pile_set_name": "PubMed Central"
} |
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