Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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[Morphological changes after permanent nerve block by freezing and ethanol injection of the sciatic nerve of the rabbit (author's transl)]. | Permanent nerve blocks by intraneurally injected alcohol are often complicated by alcohol-neuritis. Encouraging clinical experiences with permanent blocks by freezing raises the question whether morphological differences between the nerve lesions could explain the difference in their side effects. On 30 rabbits both sc... | ['Animals', 'Ethanol', 'Freezing', 'Nerve Block', 'Rabbits', 'Sciatic Nerve'] | 7,071,393 | [['B01.050'], ['D02.033.375'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['E03.155.086.711', 'E04.525.210.550'], ['B01.050.150.900.649.313.968.700'], ['A08.800.800.720.450.760']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Histological diagnosis of mediastinal lymph node metastases from renal cell carcinoma by endobronchial ultrasound-guided transbronchial needle aspiration. | Evaluation of mediastinal lymphadenopathy in patients with an intrathoracic nodule post malignancy is crucial for the determination of further treatment. Different radiological modalities are available for the detection of mediastinal lymph node metastases such as multidetector helical CT, PET-scan and PET-CT. However,... | ['Biopsy, Fine-Needle', 'Bronchoscopy', 'Carcinoma, Renal Cell', 'Diagnosis, Differential', 'Endosonography', 'Humans', 'Kidney Neoplasms', 'Lymph Nodes', 'Lymphatic Metastasis', 'Male', 'Mediastinum', 'Middle Aged'] | 17,298,469 | [['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['C04.557.470.200.0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Medical ethics and truth telling in the case of androgen insensitivity syndrome. | Should a physician always tell the truth to a patient? Is biomedical ethics too "politically correct" in certain situations? The second-place winner in the 1995 Logie Medical Ethics Essay Contest discusses whether telling the truth is the proper course for a physician dealing with certain patients. | ['Androgen-Insensitivity Syndrome', 'Ethics, Medical', 'Female', 'Humans', 'Male', 'Truth Disclosure'] | 8,630,847 | [['C12.706.316.096.500', 'C13.351.875.253.096.500', 'C16.131.939.316.096.500', 'C16.320.322.061', 'C19.391.119.096.500'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.046.800', 'I01.880.604.583.080.134.800']] | ['Diseases [C]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Genetic characterization of the secretory mutant MS-1 of Tetrahymena thermophila: vacuolarization and block in secretion of lysosomal hydrolases are caused by a single gene mutation. | The genetics and phenotypic features (light and electron microscopy) of a secretory mutant, MS-1 of Tetrahymena thermophila blocked in secretion of lysosomal acid hydrolases have been analyzed. Although blocked constitutively in secretion, MS-1 contains active lysosomal hydrolases in amounts equivalent to the wild type... | ['Alleles', 'Animals', 'Chromosome Mapping', 'Crosses, Genetic', 'Hydrolases', 'Lysosomes', 'Mutation', 'Phenotype', 'Tetrahymena thermophila', 'Vacuoles'] | 1,499,158 | [['G05.360.340.024.340.030'], ['B01.050'], ['E05.393.183'], ['E05.393.281'], ['D08.811.277'], ['A11.284.430.214.190.875.190.550'], ['G05.365.590'], ['G05.695'], ['B01.043.185.650.375.750.850.875'], ['A11.284.430.214.190.875.190.920']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aging and ESRD demographics: consequences for the practice of dialysis. | The disproportionate increase in the prevalence of chronic kidney disease (CKD) and end-stage renal disease (ESRD) in the elderly is now recognized as a national and global reality. Among the major contributing factors are the aging of the population, a growing prevalence of CKD, greater access to care, and increased c... | ['Age Factors', 'Aged', 'Humans', 'Kidney Failure, Chronic', 'Quality of Life', 'Renal Dialysis'] | 23,067,122 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E02.870.300', 'E02.912.800']] | ['Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Entomological indices of malaria transmission in Chikhwawa district, Southern Malawi. | BACKGROUND: Although malaria is highly prevalent throughout Malawi, little is known of its transmission dynamics. This paper describes the seasonal activity of the different vectors, human biting indices, sporozoite rates and the entomological inoculation rate in a low-lying rural area in southern Malawi.METHODS: Vecto... | ['Animals', 'Anopheles', 'Cattle', 'Female', 'Humans', 'Insect Vectors', 'Malaria', 'Malawi', 'Mosquito Control', 'Oocysts', 'Plasmodium', 'Rural Population', 'Seasons', 'Sporozoites'] | 23,171,123 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.120'], ['B01.050.150.900.649.313.500.380.271'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['C01.610.752.530', 'C01.920.875'], ['Z01.058.290.175.500'], ['N06.850.780.200.650.425.500'], ['A11... | ['Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Enhanced cytotoxic activity of macrophages and suppressed tumor metastases in mice irradiated with low doses of X- rays. | We showed in our previous report that a single exposure of mice to 0.1 or 0.2 Gy X-rays led to the significant inhibition of the development of artificial tumor metastases in the lungs and that the effect was related to the enhanced activity of natural killer cells. In the present study, a possible involvement of cytot... | ['Animals', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Dose-Response Relationship, Radiation', 'Lung Neoplasms', 'Macrophage Activation', 'Macrophages', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Radiation Dosage', 'X-Rays'] | 16,936,416 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['G12.287.500'], ['A11.329.372', 'A11.627.482', 'A11.7... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Investigating linear and interactive effects of shared mental models on safety and efficiency in a field setting. | Linkages between 2 types of shared mental models (SMMs)--that is, positional-goal interdependencies and cue-strategy associations--and effectiveness in an air traffic control environment were investigated. Two types of SMMs were expected to contribute uniquely, as well as interact, to predict tower safety and efficienc... | ['Adult', 'Aircraft', 'Cooperative Behavior', 'Cues', 'Efficiency', 'Female', 'Humans', 'Linear Models', 'Male', 'Models, Psychological', 'Organizational Objectives', 'Personal Construct Theory', 'Problem Solving', 'Safety'] | 15,910,147 | [['M01.060.116'], ['J01.937.285.100'], ['F01.145.813.115'], ['F02.463.425.234'], ['F02.784.692.351', 'N04.452.209'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.85... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
[Picotamide does not interfere with the anticoagulant activity of warfarin in patients wearing heart valve prostheses]. | Picotamide, a new antiplatelet drug which has only slight effects on bleeding time, could be useful, in combination with oral anticoagulants, for the prevention of thromboembolic complications in patients with heart valve prostheses. We have evaluated in a randomized, controlled, double-blind, cross-over study, the eff... | ['Aged', 'Aortic Valve', 'Double-Blind Method', 'Drug Interactions', 'Drug Therapy, Combination', 'Female', 'Heart Valve Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve', 'Phthalic Acids', 'Platelet Aggregation Inhibitors', 'Thromboembolism', 'Warfarin'] | 2,151,435 | [['M01.060.116.100'], ['A07.541.510.110'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['G07.690.773.968'], ['E02.319.310'], ['E07.695.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.541.510.507'], ['D02.241.223.805'], ['D27.505.954.502.780'],... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Caregiving, Transport-Related, and Demographic Correlates of Sedentary Behavior in Older Adults: The Senior Neighborhood Quality of Life Study. | OBJECTIVE: Excess sedentary time predicts negative health outcomes independent of physical activity. The present investigation examined informal caregiving duties and transportation-related factors as potential correlates of sedentary behavior in older adults.METHOD: Average daily sedentary time was measured via accele... | ['Age Factors', 'Aged', 'Animals', 'Automobile Driving', 'Caregivers', 'Dogs', 'Educational Status', 'Female', 'Geography', 'Humans', 'Male', 'Multivariate Analysis', 'Ownership', 'Quality of Life', 'Residence Characteristics', 'Sedentary Behavior', 'Transportation', 'Walking'] | 26,538,268 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['B01.050'], ['I03.125'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['B01.050.150.900.649.313.750.250.216.200'], ['N01.824.196'], ['H01.277.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.8... | ['Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 |
Conversion of AFLP bands into high-throughput DNA markers. | The conversion of AFLP bands into polymorphic sequence-tagged-site (STS) markers is necessary for high-throughput genotype scoring. Technical hurdles that must be overcome arise from genome complexity (particularly sequence duplication), from the low-molecular-weight nature of the AFLP bands and from the location of th... | ['Alleles', 'Base Sequence', 'Cloning, Molecular', 'DNA, Plant', 'Genetic Markers', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Sequence Tagged Sites', 'Soybeans'] | 11,361,330 | [['G05.360.340.024.340.030'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308.435'], ['D23.101.387', 'G05.695.450'], ['L01.453.245.667'], ['E05.393.620.500'], ['G05.365.795'], ['G05.360.340.024.810'], ['B01.650.940.800.575.912.250.401.750']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Rapid diagnosis of oral herpes simplex or zoster virus infections by immunofluorescence: comparison with Tzanck cell preparations and viral culture. | This study compared viral culture with routine cytology and immunofluorescent staining of oral epithelial cell smears for the diagnosis of orofacial infections due to herpes simplex virus (HSV) or herpes zoster (HZ). Twenty-one patients were studied. Viral culture gave the greatest number of positive results, with an a... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antibodies, Monoclonal', 'Child', 'Child, Preschool', 'Fluorescent Antibody Technique', 'Herpes Zoster', 'Histological Techniques', 'Humans', 'Middle Aged', 'Mouth Diseases', 'Sensitivity and Specificity', 'Stomatitis, Herpetic'] | 2,675,949 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
7-Substituted 2-phenyl-benzofurans as ER beta selective ligands. | A series of 2-(4-hydroxy-phenyl)-benzofuran-5-ols with relatively lipophilic groups in the 7-position of the benzofuran was prepared and the affinity and selectivity for ER beta was measured. Many of the analogues were found to be potent and selective ER beta ligands. Additional modifications at the benzofuran 4-positi... | ['Benzofurans', 'Cell Line, Tumor', 'Estrogen Receptor beta', 'Humans', 'Insulin-Like Growth Factor Binding Protein 4', 'Ligands', 'RNA, Messenger', 'Structure-Activity Relationship'] | 15,341,953 | [['D03.633.100.127'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.776.826.750.350.262'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.420.280'], ['D27.720.470.480'], ['D13.444.735.544'], ['G02.111.830', 'G07.690.773.997']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recurrent childhood anaplastic large cell lymphoma: a retrospective analysis of registered cases in Japan. | This report presents a retrospective study of 26 Japanese children with recurrent anaplastic large cell lymphoma. The first relapses were documented at a median of 10.5 months after the initial diagnosis. Twenty-four patients achieved a second remission. After a median follow-up period of 47 months, 18 patients are sti... | ['Adolescent', 'Antineoplastic Combined Chemotherapy Protocols', 'Child', 'Child, Preschool', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Infant', 'Japan', 'Lymphoma, Large-Cell, Anaplastic', 'Male', 'Neoplasm Recurrence, Local', 'Remission Induction', 'Re... | 16,445,832 | [['M01.060.057'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['M01.060.406'], ['M01.060.406.448'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Subclavian steal syndrome from the ipsilateral vertebral artery. | We present two cases of subclavian steal syndrome from the ipsilateral vertebral artery (VA) to the subclavian artery (SCA), one with the left VA originating from the aortic arch and the other with the left VA originating very close to the origin of the SCA, proximal to the occluded segment. In both cases, angiographic... | ['Aged', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Subclavian Artery', 'Subclavian Steal Syndrome', 'Vertebral Artery'] | 15,205,155 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700'], ['A07.015.114.839'], ['C10.228.140.300.150.956.700', 'C14.907.253.092.956.700'], ['A07.015.114.955']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Forced detachment of the CD2-CD58 complex. | The force-induced detachment of the adhesion protein complex CD2-CD58 was studied by steered molecular dynamics simulations. The forced detachment of CD2 and CD58 shows that the system can respond to an external force by two mechanisms, which depend on the loading rate. At the rapid loading rates of 70 and 35 pN/ps (pu... | ['Binding Sites', 'CD2 Antigens', 'CD58 Antigens', 'Cell Adhesion', 'Computer Simulation', 'Crystallography', 'Macromolecular Substances', 'Models, Molecular', 'Motion', 'Protein Binding', 'Protein Conformation', 'Protein Denaturation', 'Protein Folding', 'Protein Structure, Tertiary', 'Static Electricity', 'Stress, Me... | 12,668,431 | [['G02.111.570.120'], ['D23.050.301.264.894.090', 'D23.101.100.894.090'], ['D12.776.395.550.034', 'D12.776.543.550.158'], ['G04.022'], ['L01.224.160'], ['E05.196.309', 'H01.181.529.240'], ['D05'], ['E05.599.595'], ['G01.482'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709'], ['G01.154.651.750.500', 'G02.111.688.750... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Detection of prefracture hip lesions in atypical subtrochanteric fracture with dual-energy x-ray absorptiometry images. | PURPOSE: To retrospectively assess how often and how early hip dual-energy x-ray absorptiometry (DXA) images show prefracture lesions in patients with atypical subtrochanteric fracture (ASF) and determine whether DXA images with assessment of prodromal symptoms could be used for early ASF prediction.MATERIALS AND METHO... | ['Absorptiometry, Photon', 'Aged', 'Aged, 80 and over', 'Early Diagnosis', 'Female', 'Hip Fractures', 'Humans', 'Middle Aged', 'Predictive Value of Tests', 'Retrospective Studies', 'Risk Factors'] | 24,126,368 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.390'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E05.31... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Risk factors for ciliochoroidal effusion after panretinal photocoagulation. | PURPOSE: To determine the incidence, duration, and risk factors for ciliochoroidal effusion after panretinal photocoagulation.METHODS: Thirty-nine consecutive patients with diabetic retinopathy underwent ultrasound biomicroscopy of both eyes to image the ciliochoroidal space immediately before and 1 day after unilatera... | ['Adult', 'Aged', 'Anterior Eye Segment', 'Choroid Diseases', 'Ciliary Body', 'Diabetic Retinopathy', 'Female', 'Humans', 'Incidence', 'Laser Coagulation', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prospective Studies', 'Retina', 'Risk Factors', 'Ultrasonography'] | 8,637,695 | [['M01.060.116'], ['M01.060.116.100'], ['A09.371.060'], ['C11.941.160'], ['A09.371.060.160', 'A09.371.894.280'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Internuclear ophthalmoplegia associated with anti-TNFá medication. | AIM: To describe the presentation of an internuclear ophthalmoplegia (INO) associated with the use of anti-tumor necrosis factor á (anti-TNFá) medication.METHODS: A case report of a woman, aged 27 years, who developed facial numbness, blurred vision, and diplopia on right gaze. She had a history of Crohn's disease, whi... | ['Adalimumab', 'Adult', 'Anti-Inflammatory Agents', 'Crohn Disease', 'Female', 'Glucocorticoids', 'Humans', 'Magnetic Resonance Imaging', 'Methylprednisolone', 'Ocular Motility Disorders', 'Tumor Necrosis Factor-alpha'] | 25,790,247 | [['D12.776.124.486.485.114.224.060.250', 'D12.776.124.790.651.114.224.060.250', 'D12.776.377.715.548.114.224.200.250'], ['M01.060.116'], ['D27.505.954.158'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[102 patients with suspected myocarditis : Clinical presentation, diagnostics, therapy and prognosis]. | INTRODUCTION: Myocarditis is a disease which is difficult to diagnose and which includes a risk of the development of dilated cardiomyopathy and sudden cardiac death.METHODS AND PATIENTS: In this study 102 patients were included from the time period 2003-2013 after diagnosis or suspected diagnosis of myocarditis in the... | ['Adult', 'Algorithms', 'Biomarkers', 'Biopsy', 'Cardiomyopathy, Dilated', 'Death, Sudden, Cardiac', 'Diagnosis, Differential', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Myocarditis', 'Myocardium', 'Prognosis', 'Recurrence', 'Retrospective Studies', 'Risk Factors', 'Young Adult'] | 28,101,623 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['D23.101'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['C14.280.383.220', 'C23.550.260.322.250'], ['E01.171'], ['... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Analysis of endocrine activity in drinking water, surface water and treated wastewater from six countries. | The aquatic environment can contain numerous micropollutants and there are concerns about endocrine activity in environmental waters and the potential impacts on human and ecosystem health. In this study a complementary chemical analysis and in vitro bioassay approach was applied to evaluate endocrine activity in treat... | ['Biological Assay', 'Drinking Water', 'Ecosystem', 'Endocrine Disruptors', 'Environmental Monitoring', 'Glucocorticoids', 'Pesticides', 'Pharmaceutical Preparations', 'Receptors, Steroid', 'Receptors, Thyroid Hormone', 'Retinoid X Receptors', 'Waste Water', 'Water Pollutants, Chemical'] | 29,621,713 | [['E05.091'], ['D01.045.250.875.300', 'D01.248.497.158.459.650.300', 'D01.650.550.925.199', 'G07.203.100.418', 'J02.200.418'], ['G16.500.275.157', 'N06.230.124'], ['D27.505.696.353', 'D27.888.141'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['D27.720.031.700', 'D27.888.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Optimism for the Future in Younger and Older Adults. | OBJECTIVES: Research has suggested that older adults are less optimistic about their future than younger adults; however, a limitation of prior studies is that younger and older adults were forecasting to different ages and stages of life. To address this, we investigated whether there are age differences in future opt... | ['Adolescent', 'Age Factors', 'Aged, 80 and over', 'Aging', 'Female', 'Forecasting', 'Human Development', 'Humans', 'Imagination', 'Male', 'Optimism', 'Psychology, Social'] | 29,325,140 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100.080'], ['G07.345.124'], ['I01.320'], ['F01.525', 'G07.345.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.188.634'], ['F01.100.787'], ['F01.829', 'F04.096.628.829']] | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Regulation of Anisotropic Tissue Growth by Two Orthogonal Signaling Centers. | The Drosophila wing has served as a paradigm to mechanistically characterize the role of morphogens in patterning and growth. Wingless (Wg) and Decapentaplegic (Dpp) are expressed in two orthogonal signaling centers, and their gradients organize patterning by regulating the expression of well-defined target genes. By c... | ['Animals', 'Drosophila Proteins', 'Drosophila melanogaster', 'Morphogenesis', 'Repressor Proteins', 'Signal Transduction', 'TCF Transcription Factors', 'Wings, Animal', 'Wnt1 Protein'] | 32,084,357 | [['B01.050'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G07.345.500'], ['D12.776.260.703', 'D12.776.930.780'], ['G02.111.820', 'G04.835'], ['D12.776.260.730', 'D12.776.660.235.400.800', 'D12.776.664.235.400.800', 'D12.776.930.875'], ['A13.395.823'], ['D12.776.467.984.100', 'D12.776... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
2,4-Dichlorophenoxyacetic acid influx is mediated by an active transport system in Chinese hamster ovary cells. | The influx of 2,4-dichlorophenoxyacetic acid (2,4-D) into Chinese hamster ovary (CHO) cells was studied. The cells mainly took up but did not metabolize the undissociated form of the herbicide. The uptake of 2,4-D was carried out against a concentration gradient and was inhibited by sodium azide and dinitrophenol. The ... | ['2,4-Dichlorophenoxyacetic Acid', '3-O-Methylglucose', 'Aminoisobutyric Acids', 'Animals', 'Azides', 'Biological Transport, Active', 'CHO Cells', 'Cricetinae', 'Culture Media, Conditioned', 'Dinitrophenols', 'Enzyme Inhibitors', 'Herbicides', 'Hydrogen-Ion Concentration', 'Kinetics', 'Methylglucosides', 'Ouabain', 'S ... | 8,553,371 | [['D02.241.081.018.386.682.224', 'D02.241.511.316.682.149'], ['D09.408.348.500.500', 'D09.408.514.622.500'], ['D02.241.081.114.968.249', 'D12.125.070.075', 'D12.125.190.055'], ['B01.050'], ['D01.625.100', 'D02.159'], ['G03.143.310'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250'], ['D27... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serration pattern analysis for differentiating epidermolysis bullosa acquisita from other pemphigoid diseases. | BACKGROUND: Direct immunofluorescence (DIF) microscopy of a skin biopsy specimen is the reference standard for the diagnosis of pemphigoid diseases (PDs). Serration pattern analysis enables the differentiation of epidermolysis bullosa acquisita (EBA) from other PDs using DIF microscopy alone. However, practice gaps nee... | ['Diagnosis, Differential', 'Epidermolysis Bullosa Acquisita', 'Humans', 'Microscopy, Fluorescence', 'Observer Variation', 'Pemphigoid, Bullous', 'Retrospective Studies'] | 29,154,993 | [['E01.171'], ['C16.131.831.493.080', 'C17.800.804.493.080', 'C17.800.827.275.080', 'C17.800.865.410.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.458', 'E05.595.458'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['C17.800.865.690', 'C20.111.730'], ['E05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Relationships between socioeconomic and lifestyle factors and indoor air quality in French dwellings. | BACKGROUND: To date, few studies have analyzed the relationships between socioeconomic status (SES) and indoor air quality (IAQ).OBJECTIVE: The aim of this study was to examine the relationships between socioeconomic and other factors and indoor air pollutant levels in French homes.METHODS: The indoor air concentration... | ['Air Pollution, Indoor', 'Aldehydes', 'France', 'Humans', 'Life Style', 'Socioeconomic Factors', 'Volatile Organic Compounds'] | 25,935,319 | [['N06.850.460.100.080'], ['D02.047'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458'], ['I01.880.853.996', 'N01.824'], ['D02.974']] | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Resistance to medical therapy of gastric ulcers in rheumatic disease patients taking aspirin. A double-blind study with cimetidine and follow-up. | Little is known about healing or recurrence of aspirin-induced gastric ulcers if aspirin intake is continued. A double-blind controlled study compared cimetidine plus antacids as needed (prn) with placebo plus prn antacids in healing aspirin-associated gastric ulcers during continued salicylate ingestion in 18 rheumati... | ['Antacids', 'Aspirin', 'Cimetidine', 'Double-Blind Method', 'Follow-Up Studies', 'Guanidines', 'Humans', 'Placebos', 'Prospective Studies', 'Rheumatic Heart Disease', 'Stomach Ulcer'] | 7,140,494 | [['D27.505.519.170', 'D27.505.954.483.080'], ['D02.455.426.559.389.657.410.595.176'], ['D02.078.370.200', 'D03.383.129.308.130'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D02.078.370... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pharmacokinetic and pharmacodynamic properties of batifiban coadministered with antithrombin agents in Chinese healthy volunteers. | The combined use of batifiban, a synthetic platelet GPII b/ IIIa receptor antagonist, and antithrombin agents is an attractive option for the treatment of patients with non-ST-segment elevation (NSTE) acute coronary syndrome (ACS) and those scheduled for percutaneous coronary intervention. To observe whether antithromb... | ['Administration, Oral', 'Adolescent', 'Adult', 'Area Under Curve', 'Aspirin', 'China', 'Clopidogrel', 'Drug Administration Schedule', 'Female', 'Fibrinolytic Agents', 'Heparin', 'Humans', 'Infusions, Intravenous', 'Injections, Intravenous', 'Male', 'Metabolic Clearance Rate', 'Peptides, Cyclic', 'Platelet Aggregation ... | 24,142,738 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D02.455.426.559.389.657.410.595.176'], ['Z01.252.474.164'], ['D02.886.778.823.500.500', 'D03.383.725.849.500.500', 'D03.383.903.830.500.500', 'D03.633.100.928.500.500'], ['E02.319.283'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Comprehensive 3D-QSAR and binding mode of BACE-1 inhibitors using R-group search and molecular docking. | The â-enzyme (BACE), which takes an active part in the processing of amyloid precursor protein, thereby leads to the production of amyloid-â (Aâ) in the brain, is a major therapeutic target against Alzheimer's disease. The present study is aimed at studying 3D-QSAR of BACE-1 inhibitors and their binding mode. We build ... | ['Amyloid Precursor Protein Secretases', 'Aspartic Acid Endopeptidases', 'Binding Sites', 'Drug Design', 'Humans', 'Hydrogen Bonding', 'Models, Molecular', 'Molecular Docking Simulation', 'Molecular Structure', 'Protease Inhibitors', 'Protein Binding', 'Quantitative Structure-Activity Relationship'] | 24,004,830 | [['D08.811.277.656.300.032'], ['D08.811.277.656.074.500', 'D08.811.277.656.300.048'], ['G02.111.570.120'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.282'], ['E05.599.595'], ['E05.599.595.249', 'L01.224.160.249'], ['G02.111.570', 'G02.466'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Asymmetric retraction of growth cone filopodia following focal inactivation of calcineurin. | The neuronal growth cone is thought to be the site of decision making in nerve growth and guidance. One likely mechanism of how the growth cone translates various extracellular cues into directed motility involves rises in intracellular calcium. A variety of physiological cues, such as adhesion molecules and neurotrans... | ['Animals', 'Calcineurin', 'Calmodulin-Binding Proteins', 'Cattle', 'Cell Division', 'Cell Movement', 'Cells, Cultured', 'Chick Embryo', 'Cyclosporine', 'Ganglia, Spinal', 'Lasers', 'Neurites', 'Phosphoprotein Phosphatases', 'Polyenes', 'Rosaniline Dyes', 'Signal Transduction', 'Sirolimus', 'Tacrolimus'] | 7,544,441 | [['B01.050'], ['D08.811.277.352.650.625.150', 'D12.644.360.087', 'D12.776.476.087'], ['D12.776.157.142'], ['B01.050.150.900.649.313.500.380.271'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['D04.345.566.235.300'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Neonatology nurses' knowledge about Peripherally Inserted Central Venous Catheter]. | The Peripherally Inserted Central Catheter (PICC) has been used as a safe venous access for infants at risk. The aim of this study was to describe the knowledge and practice of nurses from the five public Neonatal Intensive Care Units, of Recife-PE, Brazil, about the use of the PICC. The sample was comprised by 52 nurs... | ['Adult', 'Catheterization, Peripheral', 'Central Venous Catheters', 'Clinical Competence', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Infant, Newborn', 'Intensive Care Units, Neonatal', 'Male', 'Neonatal Nursing'] | 22,751,707 | [['M01.060.116'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['E07.132.750.500'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['N02.278.388.493.390.380'], ['H02.478.676.390... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Competition between two virulent Marek's disease virus strains in vivo. | Previous studies have demonstrated the presence of multiple strains of Marek's disease virus simultaneously circulating within poultry flocks, leading to the assumption that individual birds are repeatedly exposed to a variety of virus strains in their lifetime. Virus competition within individual birds may be an impor... | ['Animals', 'Antibodies, Monoclonal', 'Chickens', 'Coinfection', 'Herpesvirus 2, Gallid', 'Immunohistochemistry', 'Marek Disease', 'Microbial Interactions', 'Population Dynamics', 'Sequence Analysis, DNA', 'Species Specificity', 'Statistics, Nonparametric', 'Virulence'] | 22,702,454 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['C01.218'], ['B04.280.382.100.562.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Effect of soil pH on as hyperaccumulation capacity in fern species, Pityrogramma calomelanos. | Arsenic uptake by hyperaccumulator plant species depends on many different environmental factors. Soil pH is one of the most important factors due to its combined effect on both chemical and biological processes. In greenhouse experiment, the effect of pH (within the pH range 3.6 - 8.9) on As uptake as well as biomass ... | ['Arsenic', 'Biodegradation, Environmental', 'Ferns', 'Hydrogen-Ion Concentration', 'Mining', 'Soil'] | 24,620,585 | [['D01.268.513.249'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['B01.650.940.800.575.912.063'], ['G02.300'], ['J01.576.655.875.500'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
A complex pattern of disposition of phenytoin in severe intoxication. | A 5-year-old child developed phenytoin (diphenylhydantoin, DPH) toxicity after receiving 500 mg of the drug daily for 3 weeks. Plasma, urine, and duodenal fluid were collected for assay of DPH and its metabolites. The peak plasma concentration of DPH was 108 mug/ml, and the decline in plasma level did not fit first-ord... | ['Child, Preschool', 'Duodenum', 'Glucuronates', 'Humans', 'Hydrogen-Ion Concentration', 'Kinetics', 'Male', 'Medication Errors', 'Phenytoin', 'Protein Binding', 'Seizures', 'Serum Albumin', 'Solubility', 'Time Factors'] | 238,781 | [['M01.060.406.448'], ['A03.556.124.684.124', 'A03.556.875.249'], ['D02.241.081.844.915.162', 'D02.241.152.811.162', 'D02.241.511.902.915.162', 'D09.811.922.162'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['E02.319.529', 'N02.421.450.500'], ['D03.383.129.308.432.555.... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Differences in pain knowledge in cancer patients with and without pain. | PURPOSE: The authors determined: 1) whether there were differences in knowledge about pain between oncology outpatients with and without cancer-related pain and 2) whether there were relationships between selected patient characteristics (age, gender, education, Karnofsky performance status, pain intensity, and pain du... | ['Adult', 'Educational Measurement', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasms', 'Outpatients', 'Pain', 'Patient Education as Topic', 'Retrospective Studies', 'Surveys and Questionnaires'] | 9,128,495 | [['M01.060.116'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04'], ['M01.643.630'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['I02.233.332.500', 'N02.421.726.407.680'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Mammalian cAMP-responsive element can activate transcription in yeast and binds a yeast factor(s) that resembles the mammalian transcription factor ANF. | The human ATF and AP1 transcription factors bind to highly related DNA sequences. Their consensus binding sites differ by a single nucleotide, but this single change is crucial in determining factor binding specificity. We have previously identified an AP1 (yAP1) binding activity in yeast. In this report we identify a ... | ['Activating Transcription Factors', 'Adenoviruses, Human', 'Alkaline Phosphatase', 'Base Sequence', 'Blood Proteins', 'Cell Nucleus', 'Cyclic AMP', 'Gene Expression Regulation', 'Genes, Fungal', 'HeLa Cells', 'Humans', 'Molecular Sequence Data', 'Phosphorylation', 'Promoter Regions, Genetic', 'Protein Kinases', 'Sacch... | 2,538,834 | [['D12.776.260.108.061', 'D12.776.930.127.061'], ['B04.280.030.500.350'], ['D08.811.277.352.650.035'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.124'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.06... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Uptake of aqueous and dietary metals by mussel Perna viridis with different Cd exposure histories. | The influences of different Cd pre-exposure regimes (route, concentration, and duration of Cd exposure) on the bioavailability of Cd, Ag, Hg, and Zn to the green mussels Perna viridis were quantified in this study. Following pre-exposing the mussels to Cd, we measured the mussel's tissue Cd concentration and clearance ... | ['Animals', 'Biological Availability', 'Bivalvia', 'Body Burden', 'Cadmium', 'Metals', 'Tissue Distribution'] | 16,382,965 | [['B01.050'], ['G03.787.151', 'G07.690.725.129'], ['B01.050.500.644.080'], ['E05.799.638.231', 'N06.850.460.200'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D01.552'], ['G03.787.917', 'G07.690.725.949']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Low T3 syndrome and left ventricular diastolic function]. | BACKGROUND: Recent data suggest that low triiodothyronine (T3) syndrome may contribute to the pathophysiology of cardiac diseases. Because the development of diastolic dysfunction occurs early in a failing heart, we evaluated whether patients with low T3 syndrome show abnormalities in diastolic function, also in absenc... | ['Aged', 'Biomarkers', 'Case-Control Studies', 'Diastole', 'Echocardiography, Doppler', 'Euthyroid Sick Syndromes', 'Female', 'Heart Diseases', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Retrospective Studies', 'Thyrotropin', 'Thyroxine', 'Triiodothyronine', 'Ventricular Dysfunction, Left', 'Ventric... | 19,771,751 | [['M01.060.116.100'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G09.330.580.295', 'G11.427.494.554.250', 'G11.427.494.570.295'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['C19.874.255'], ['C14.280'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Highly sensitive two-site immunoradiometric assay of parathyrin, and its clinical utility in evaluating patients with hypercalcemia. | We have developed a highly sensitive, two-site immunoradiometric assay (IRMA) for human parathyrin (PTH) that is specific for the intact, secreted, biologically active 84-amino-acid peptide. This assay has several technical advantages: it does not detect even high concentrations of inactive carboxyl-terminal fragments,... | ['Humans', 'Hypercalcemia', 'Hyperparathyroidism', 'Indicators and Reagents', 'Neoplasms', 'Parathyroid Hormone', 'Radioimmunoassay', 'Reference Values'] | 3,608,153 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.174.451', 'C18.452.950.340'], ['C19.642.355'], ['D27.720.470.410'], ['C04'], ['D06.472.699.590', 'D12.644.548.587'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['E05.978.810']] | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of gamma-aminobutyric acid on lordosis behavior and dopamine activity in estrogen primed spayed female rats. | In the first experiment the role of gamma-aminobutyric acid (GABA) in the display of lordosis behavior was examined in septal-lesioned and sham-operated ovariectomized rats. Following estradiol benzoate (EB) priming, septal-lesioned rats were tested for lordosis behavior before and after bilateral infusion of picrotoxi... | ['Animals', 'Castration', 'Dopamine', 'Estradiol', 'Female', 'Muscimol', 'Picrotoxin', 'Propionates', 'Rats', 'Septal Nuclei', 'Sexual Behavior, Animal', 'Substantia Nigra', 'gamma-Aminobutyric Acid'] | 7,357,416 | [['B01.050'], ['E04.270.282', 'E04.950.165'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D03.383.129.462.470', 'D23.946.587.587'], ['D02.455.426.392.368.367.800', 'D02.540.552'], ['D02.241.081.751', 'D10.251.400.706'], ['B... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Genetic aspects of male infertility]. | We examined 118 men with infertility. Among them we identified phenotypic syndromes associated with infertility in 4 and chromosomal abnormalities in 16. Further molecular genetic study of 98 infertile men found that microdeletions in AZFc-locus had 3, pathological AR allele had 2, CFTR gene mutation had 4 of them. In ... | ['Chromosome Aberrations', 'Chromosomes, Human, Y', 'Cystic Fibrosis Transmembrane Conductance Regulator', 'DNA Fragmentation', 'Female', 'Humans', 'Infertility, Male', 'Kartagener Syndrome', 'Karyotyping', 'Male', 'Mutation', 'Oligospermia', 'Pedigree', 'Receptors, Androgen'] | 24,850,600 | [['C23.550.210', 'G05.365.590.175'], ['A11.284.187.520.300.505.757', 'A11.284.187.865.983.500', 'G05.360.162.520.300.505.757', 'G05.360.162.865.983.500'], ['D12.776.157.530.100.304.500', 'D12.776.157.530.400.175.125', 'D12.776.157.530.450.074.500.500.500.500', 'D12.776.543.550.450.175.125', 'D12.776.543.585.100.304.500... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Achievement of recommended glucose and blood pressure targets in patients with type 2 diabetes and hypertension in clinical practice - study rationale and protocol of DIALOGUE. | BACKGROUND: Patients with type 2 diabetes have 2-4 times greater risk for cardiovascular morbidity and mortality than those without, and this is even further aggravated if they also suffer from hypertension. Unfortunately, less than one third of hypertensive diabetic patients meet blood pressure targets, and more than ... | ['Antihypertensive Agents', 'Biomarkers', 'Blood Glucose', 'Blood Pressure', 'Cardiovascular Diseases', 'Cerebrovascular Disorders', 'Diabetes Mellitus, Type 2', 'Germany', 'Glycated Hemoglobin A', 'Guideline Adherence', 'Humans', 'Hypertension', 'Hypoglycemic Agents', 'Practice Guidelines as Topic', "Practice Patterns... | 23,216,660 | [['D27.505.954.411.162'], ['D23.101'], ['D09.947.875.359.448.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14'], ['C10.228.140.300', 'C14.907.253'], ['C18.452.394.750.149', 'C19.246.300'], ['Z01.542.315'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['N04.76... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Circulating tumor cells from patients with advanced prostate and breast cancer display both epithelial and mesenchymal markers. | During cancer progression, malignant cells undergo epithelial-mesenchymal transitions (EMT) and mesenchymal-epithelial transitions (MET) as part of a broad invasion and metastasis program. We previously observed MET events among lung metastases in a preclinical model of prostate adenocarcinoma that suggested a relation... | ['Biomarkers, Tumor', 'Breast Neoplasms', 'Epithelial-Mesenchymal Transition', 'Female', 'Humans', 'Male', 'Neoplasm Staging', 'Neoplastic Cells, Circulating', 'Prostatic Neoplasms'] | 21,665,936 | [['D23.101.140'], ['C04.588.180', 'C17.800.090.500'], ['G04.356.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789.625'], ['A11.642', 'C04.697.650.900', 'C23.550.727.650.900'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intravaginal energy-based devices and sexual health of female cancer survivors: a systematic review and meta-analysis. | A systematic review and meta-analysis was undertaken to assess the efficacy and safety of intravaginal energy-based therapies (laser and radiofrequency) on sexual health of cancer survivors (CS) (breast cancer (BCS) and/or gynecological cancer (GCS)). PubMed, Scopus, Web of Science, and Cochrane Library were searched u... | ['Cancer Survivors', 'Dyspareunia', 'Female', 'Humans', 'Laser Therapy', 'Sexual Health', 'Vagina'] | 31,396,795 | [['M01.860.350'], ['C12.294.644.242', 'C13.351.500.665.313', 'F03.835.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['N01.400.663'], ['A05.360.319.779']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Using uncertainty and sensitivity analyses in socioecological agent-based models to improve their analytical performance and policy relevance. | Agent-based models (ABMs) have been widely used to study socioecological systems. They are useful for studying such systems because of their ability to incorporate micro-level behaviors among interacting agents, and to understand emergent phenomena due to these interactions. However, ABMs are inherently stochastic and ... | ['Agriculture', 'Computer Simulation', 'Conservation of Natural Resources', 'Ecosystem', 'Environmental Policy', 'Geography', 'Michigan', 'Models, Biological', 'Probability', 'Soil', 'Uncertainty'] | 25,340,764 | [['J01.040'], ['L01.224.160'], ['J01.256', 'N06.230.080'], ['G16.500.275.157', 'N06.230.124'], ['I01.655.500.608.180', 'I01.880.604.825.608.180', 'N03.623.500.608.180', 'N06.230.204'], ['H01.277.500'], ['Z01.107.567.875.350.500', 'Z01.107.567.875.510.500'], ['E05.599.395'], ['E05.318.740.600', 'G17.680', 'N05.715.360.7... | ['Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chem... | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 |
Prevalence and relationship of olfactory dysfunction and tinnitus among middle- and old-aged population in Korea. | Olfactory dysfunction and tinnitus are age-related otorhinolaryngological disorders with a high prevalence in the elderly population and share several common clinical features. However, there is no study investigating the relationship between these two diseases. We studied the prevalence of olfactory dysfunction and ti... | ['Alcohol Drinking', 'Female', 'Humans', 'Male', 'Mental Health', 'Metabolic Syndrome', 'Middle Aged', 'Nutrition Surveys', 'Odds Ratio', 'Olfaction Disorders', 'Prevalence', 'Republic of Korea', 'Severity of Illness Index', 'Smoking', 'Surveys and Questionnaires', 'Tinnitus'] | 30,352,085 | [['F01.145.317.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.418', 'N01.400.500'], ['C18.452.394.968.500.570', 'C18.452.625'], ['M01.060.116.630'], ['E05.318.308.980.485', 'N05.715.360.300.800.469', 'N06.850.505.616', 'N06.850.520.308.980.469'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.62... | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The endometrial receptivity array for diagnosis and personalized embryo transfer as a treatment for patients with repeated implantation failure. | OBJECTIVE: To demonstrate the clinical value of the endometrial receptivity array (ERA) in patients with repeated implantation failure (RIF), for guiding their personalized embryo transfer (pET) as a novel therapeutic strategy.DESIGN: Prospective interventional multicenter clinical trial.SETTING: University-affiliated ... | ['Abortion, Habitual', 'Adult', 'Biopsy', 'Embryo Implantation', 'Embryo Transfer', 'Endometrium', 'Female', 'Humans', 'Infertility, Female', 'Microarray Analysis', 'Middle Aged', 'Pregnancy', 'Prognosis', 'Treatment Outcome', 'Young Adult'] | 23,756,099 | [['C13.703.039.089'], ['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['G08.686.784.170.104.500'], ['E02.875.800.500', 'E05.820.800.500'], ['A05.360.319.679.490'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of the protective efficacy of a commercial vaccine against different antigenic groups of H9N2 influenza viruses in chickens. | Despite the long-term vaccination programs implemented in China, H9N2 avian influenza viruses (AIVs) continue to persist in chicken populations, even in vaccinated flocks. We previously demonstrated that H9N2 AIV isolated from chickens in China also underwent antigenic drift and evolved into distinct antigenic groups (... | ['Animals', 'Antigens, Viral', 'Chickens', 'China', 'Influenza A Virus, H9N2 Subtype', 'Influenza Vaccines', 'Influenza in Birds'] | 22,019,289 | [['B01.050'], ['D23.050.327'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['Z01.252.474.164'], ['B04.820.480.968.405.400.900'], ['D20.215.894.899.302'], ['C01.925.782.620.300', 'C22.131.450']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Detection of leachables and cytotoxicity after exposure to methacrylate- and epoxy-based root canal sealers in vitro. | Root canal sealing materials may have toxic potential in vitro depending on the cell line, cytotoxicity assay, material chemistry, and degree of polymer curing. The aims of the present study were to detect leaching components from epoxy- or methacrylate-based root canal sealers and to investigate the degree of cytotoxi... | ['Acinar Cells', 'Animals', 'Cell Culture Techniques', 'Cell Death', 'Chromatography, Liquid', 'Cytotoxins', 'Epoxy Resins', 'Gas Chromatography-Mass Spectrometry', 'Polymethacrylic Acids', 'Rats', 'Root Canal Filling Materials', 'Salivary Glands'] | 24,028,598 | [['A11.031'], ['B01.050'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.146'], ['E05.196.181.400'], ['D27.888.569.213'], ['D05.750.716.822.461', 'D25.720.716.822.461', 'J01.637.051.720.716.822.461'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D02.241.081.069.800', 'D05.750.716.... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Autologous adipose-derived stem cell transplantation enhances healing of wound with exposed bone in a rat model. | OBJECTIVES: Soft tissue wounds with exposed bone often require extended healing times and can be associated with severe complications. We describe the ability of artificial dermis with autogenic adipose-derived stem cells (ADSCs) to promote the healing of wounds with exposed bone in a rat model.METHODS: Adipose tissues... | ['Adipose Tissue', 'Animals', 'Biomarkers', 'Cell Differentiation', 'Cell Proliferation', 'Disease Models, Animal', 'Female', 'Immunohistochemistry', 'Rats', 'Real-Time Polymerase Chain Reaction', 'Soft Tissue Injuries', 'Stem Cell Transplantation', 'Stem Cells', 'Transplantation, Autologous', 'Wound Healing'] | 31,083,652 | [['A10.165.114'], ['B01.050'], ['D23.101'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.2... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Absence of ribosomal DNA amplification in the meroistic (telotrophic) ovary of the large milkweed bug Oncopeltus fasciatus (Dallas) (Hemiptera: Lygaeidae). | In the typical meroistic insect ovary, the oocyte nucleus synthesizes little if any RNA. Nurse cells or trophocytes actively synthesize ribosomes which are transported to and accumulated by the oocyte. In the telotrophic ovary a morphological separation exists, the nurse cells being localized at the apical end of eac... | ['Animals', 'Cell Nucleus', 'Cytosine', 'DNA', 'DNA Replication', 'DNA, Satellite', 'Female', 'Genes', 'Guanine', 'Hemiptera', 'Male', 'Oocytes', 'Ovary', 'RNA, Ribosomal', 'Testis'] | 1,158,969 | [['B01.050'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D03.383.742.698.421'], ['D13.444.308'], ['G02.111.225', 'G05.226'], ['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.360.340.024.220.150', 'G05.360.340.024.850.150'], ['G05.360.340.024.340'], ['D03.633.100.759.758.399.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A case of pediatric cardiomyopathy with severely restrictive physiology. | A rare case of a 6-year-old male with idiopathic familial cardiomyopathy manifesting severely restrictive physiology is reported. The patient showed congestive heart failure with dilatation of both atria with a normal ventricular cavity. A square-root configuration was revealed in the ventricular pressure tracings. His... | ['Bundle-Branch Block', 'Cardiomyopathy, Hypertrophic', 'Cardiomyopathy, Restrictive', 'Child', 'Diagnosis, Differential', 'Electrocardiography', 'Hemodynamics', 'Humans', 'Male', 'Myocardial Contraction', 'Myocardium'] | 1,487,458 | [['C14.280.067.558.323', 'C14.280.123.500.323', 'C23.550.073.425.100'], ['C14.280.238.100', 'C14.280.484.048.750.070.160'], ['C14.280.238.160'], ['M01.060.406'], ['E01.171'], ['E01.370.370.380.240', 'E01.370.405.240'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.330.580', 'G11.427.494.570'],... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle. | Casein kinase I delta (CKIdelta) and casein kinase I epsilon (CKIepsilon) have been implicated in the response to DNA damage, but the understanding of how these kinases are regulated remains incomplete. In vitro, these kinases rapidly autophosphorylate, predominantly on their carboxyl-terminal extensions, and this auto... | ['3T3 Cells', 'Adenosine Triphosphate', 'Animals', 'Casein Kinases', 'Cells, Cultured', 'Enzyme Inhibitors', 'Escherichia coli', 'HeLa Cells', 'Homeostasis', 'Humans', 'Isoenzymes', 'Marine Toxins', 'Mice', 'Okadaic Acid', 'Oxazoles', 'Phosphoprotein Phosphatases', 'Phosphorylation', 'Protein Kinases', 'Rats'] | 9,632,646 | [['A11.251.210.100', 'A11.329.228.100'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D08.811.913.696.620.682.700.140', 'D12.776.476.150'], ['A11.251'], ['D27.505.519.389'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['A11.251.210.190.400', 'A11.251.860.180.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunogenetic studies of the platelet-specific antigen P1A1 (Zw(a)). | The phenotype frequency of the platelet-specific antigens P1A1/A2 ( = Zw(a,b)) in the German population (N = 711) is 97.75% and 2.25% respectively. The corresponding gene frequencies are P1A1 0.85; P1A2 0.15. The P1A1 determinant is codominantly inherited (19 families; 151 family members). There is a strong gene dosage... | ['Antilymphocyte Serum', 'Blood Platelets', 'Chromosome Mapping', 'Female', 'Genetic Linkage', 'Genotype', 'Histocompatibility Testing', 'Humans', 'Isoantigens', 'Male', 'Pedigree', 'Phenotype'] | 7,068,170 | [['A12.207.152.846.500.203', 'D12.776.124.486.485.114.573.203', 'D12.776.124.790.651.114.573.203', 'D12.776.377.715.548.114.573.203', 'D20.215.401.203'], ['A11.118.188', 'A15.145.229.188'], ['E05.393.183'], ['G05.348'], ['G05.380'], ['E01.370.225.812.385', 'E05.200.812.385', 'E05.478.594.385'], ['B01.050.150.900.649.31... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Failure of infused beta-hydroxybutyrate to decrease proteolysis in man. | Ketone bodies have been suggested to have a protein-sparing effect, since infusion of Na-beta-hydroxybutyrate in man decreases plasma alanine concentrations and urinary nitrogen (N) excretion. To test this hypothesis, six normal postabsorptive volunteers were infused with Na-beta-hydroxybutyrate for 3 h. Rates of gluco... | ['3-Hydroxybutyric Acid', 'Adolescent', 'Adult', 'Alanine', 'Animals', 'Bicarbonates', 'Blood Glucose', 'Blood Proteins', 'Dogs', 'Female', 'Glucagon', 'Humans', 'Hydrogen-Ion Concentration', 'Hydroxybutyrates', 'Insulin', 'Ketone Bodies', 'Kinetics', 'Leucine', 'Male', 'Sodium Bicarbonate'] | 6,298,041 | [['D02.241.081.114.937.349', 'D02.241.511.429.349', 'D02.522.585.087', 'D10.251.400.143.781.500'], ['M01.060.057'], ['M01.060.116'], ['D12.125.042'], ['B01.050'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['D09.947.875.359.448.500'], ['D12.776.124'], ['B01.050.150.900.649.313.750.250.216.200'], ['D06.472.699.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rapid and simple purification of human immunodeficiency virus 1 epitope gp41. | In order to develop a reliable and inexpensive serodiagnostic method, part of the transmembrane glycoprotein gene of HIV-1, gp41', (HIV-env 548-646) was cloned into an expression vector, pCT10 with a sequence encoding a hydroxylamine cleavage site and with a part of Lac Z gene (Lac 2": 834 base pairs) as a fusion partn... | ['Base Sequence', 'Cloning, Molecular', 'DNA, Viral', 'Enzyme-Linked Immunosorbent Assay', 'Epitopes', 'Escherichia coli', 'Genes, env', 'Genetic Vectors', 'HIV Envelope Protein gp41', 'HIV Infections', 'HIV-1', 'Humans', 'Molecular Sequence Data', 'Plasmids', 'Virology'] | 7,679,396 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308.568'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D23.050.550'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.364.875.17... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Bi-Force: large-scale bicluster editing and its application to gene expression data biclustering. | The explosion of the biological data has dramatically reformed today's biological research. The need to integrate and analyze high-dimensional biological data on a large scale is driving the development of novel bioinformatics approaches. Biclustering, also known as 'simultaneous clustering' or 'co-clustering', has bee... | ['Algorithms', 'Animals', 'Cluster Analysis', 'Computer Simulation', 'Databases, Genetic', 'Gene Expression Profiling', 'Gene Ontology', 'Humans', 'Models, Genetic', 'Oligonucleotide Array Sequence Analysis', 'Principal Component Analysis', 'Software'] | 24,682,815 | [['G17.035', 'L01.224.050'], ['B01.050'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['L01.224.160'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['E05.393.332'], ['H01.158.273.343.249.099', 'H01.770.644.145.350.124', 'L01.224.050.375.480.500.500', 'L01.313.500.750.300.550.500.50... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Ultrastructure of Giardia duodenalis trophozoites group from hamster: some relevant aspects. | Trophozoites of Giardia duodenalis group obtained from fragments or scratched of hamster's mucosa were examined by transmission electron microscopy. The fine structure of the trophozoites are presented and compared with those described for other animals. Some of the trophozoites present the cytoplasm full of glycogen, ... | ['Animals', 'Cricetinae', 'Giardia', 'Mesocricetus', 'Microscopy, Electron'] | 1,842,435 | [['B01.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.237.385'], ['B01.050.150.900.649.313.992.635.075.250.500'], ['E01.370.350.515.402', 'E05.595.402']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Using iron deficiency tests for colorectal cancer screening: a feasibility study in one UK general practice. | Iron deficiency is common at presentation in colorectal cancer. Testing for it may complement other screening tests such as faecal occult blood testing and sigmoidoscopy. We therefore examined the feasibility of offering iron deficiency testing to patients in a primary care setting in the UK, offering testing to all 12... | ['Aged', 'Anemia, Iron-Deficiency', 'Clinical Protocols', 'Colorectal Neoplasms', 'Family Practice', 'Feasibility Studies', 'Humans', 'Middle Aged', 'Wales'] | 15,304,148 | [['M01.060.116.100'], ['C15.378.071.196.300', 'C18.452.565.100'], ['E02.183', 'N05.715.360.330.125'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['H02.403.340.500'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
An equilibrium study of metal ion binding to human plasma coagulation factor XIII. | 1. The binding of Ca2+ to plasma coagulation Factor XIII from man and from cow caused a small decrease in the intrinsic fluorescence of the protein with a dissociation constant of 0.1 mM. A similar decrease was observed with the thrombin-activated Factors (Factors XIIa). The decrease in protein fluorescence was also ca... | ['Animals', 'Binding Sites', 'Calcium', 'Cations, Divalent', 'Cattle', 'Dialysis', 'Factor XIII', 'Humans', 'Kinetics', 'Spectrometry, Fluorescence', 'Thrombin'] | 629,762 | [['B01.050'], ['G02.111.570.120'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.248.497.300.333'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.353', 'G02.186'], ['D08.622.505', 'D12.776.124.125.475', 'D12.776.811.243.505', 'D23.119.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibitory effect of live-attenuated Listeria monocytogenes-based vaccines expressing MIA gene on malignant melanoma. | Listeria monocytogenes (LM), a Gram-positive facultative intracellular bacterium, can be used as an effective exogenous antigen expression vector in tumor-target therapy. But for successful clinical application, it is necessary to construct attenuated LM stain that is safe yet retains the potency of LM based on the ful... | ['Animals', 'Cancer Vaccines', 'Extracellular Matrix Proteins', 'Listeria monocytogenes', 'Male', 'Melanoma', 'Mice', 'Mice, Inbred C57BL', 'Vaccines, Attenuated'] | 22,886,976 | [['B01.050'], ['D20.215.894.200'], ['D12.776.860.300'], ['B03.353.500.500.500', 'B03.510.100.500.500', 'B03.510.460.400.410.485.500'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Universal diagnostic oligonucleotide microarray for subtyping of human and animal influenza A viruses]. | The diagnostic oligonucleotide microarray for subtyping of human and animal influenza A viruses (IAVs) was developed. We proposed a simple method of the fluorescent labeling of genomic segments of all known IAVs subtypes, the composition of the hybridization buffer, as well as the software of the data processing. 48 IA... | ['Animals', 'Genome, Viral', 'Humans', 'Influenza A virus', 'Influenza, Human', 'Lab-On-A-Chip Devices', 'Molecular Typing', 'Oligonucleotide Array Sequence Analysis', 'Orthomyxoviridae Infections', 'RNA, Viral', 'Software'] | 24,640,169 | [['B01.050'], ['G05.360.340.358.840'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['E07.305.343.500'], ['E01.370.225.875.150.125.457', 'E05.200.875.150.125.457', 'E05.393.542'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The diagnostic properties of laboratory tests for rabies. | We have prospectively followed 915 victims bitten by 664 dogs between January 1984 and December 1985 to assess death and severe neurological disability. These dogs were brought either by the owner or bite victims to Ta Pra Diagnostic Centre for detection of rabies. Each patient was followed every three months by mail f... | ['Animals', 'Clinical Laboratory Techniques', 'Dogs', 'Fluorescent Antibody Technique', 'Follow-Up Studies', 'Humans', 'Predictive Value of Tests', 'Rabies', 'Rabies Vaccines', 'Vaccination'] | 3,326,844 | [['B01.050'], ['E01.370.225', 'E05.200'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The beta(2)-adrenergic receptor delivers an antiapoptotic signal to cardiac myocytes through G(i)-dependent coupling to phosphatidylinositol 3'-kinase. | Recent studies have shown that chronic beta-adrenergic receptor (beta-AR) stimulation alters cardiac myocyte survival in a receptor subtype-specific manner. We examined the effect of selective beta(1)- and beta(2)-AR subtype stimulation on apoptosis induced by hypoxia or H(2)O(2) in rat neonatal cardiac myocytes. Altho... | ['Apoptosis', 'Cells, Cultured', 'Chromones', 'Enzyme Inhibitors', 'Flavonoids', 'GTP-Binding Protein alpha Subunits, Gi-Go', 'Humans', 'Hydrogen Peroxide', 'Mitogen-Activated Protein Kinases', 'Morpholines', 'Myocardium', 'Pertussis Toxin', 'Phosphatidylinositol 3-Kinases', 'Receptors, Adrenergic, beta-1', 'Receptors,... | 11,110,775 | [['G04.146.954.035'], ['A11.251'], ['D03.383.663.283.266', 'D03.633.100.150.266'], ['D27.505.519.389'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['D08.811.277.040.330.300.200.100.200', 'D12.644.360.360.100.200', 'D12.776.157.325.332.100.200', 'D12.776.476.375.100.200', 'D12.776.543.325.100.200'], ['B01.0... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Injuries and use of protective equipment among college in-line skaters. | In-line skating injuries and protective gear use were explored in a sample of college students (n = 217). A minority of respondents wore protective gear. One third of skaters had experienced at least one minor injury, and a smaller percentage had experienced fractures or head injuries. Most minor injuries occurred duri... | ['Adolescent', 'Adult', 'Athletic Injuries', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Protective Devices', 'Skating', 'Students'] | 9,006,646 | [['M01.060.057'], ['M01.060.116'], ['C26.115'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.700', 'J01.637.708'], ['I03.450.642.845.700'], ['M01.848']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Cloning and expression of cDNA for arginine-specific ADP-ribosyltransferase from chicken bone marrow cells. | Two arginine-specific ADP-ribosyltransferase cDNAs (designated AT1 and AT2) were cloned from chicken bone marrow cells. Each cDNA encodes a different peptide of 312 amino acid residues. Homology of deduced amino acid sequences between AT1 and AT2 was 78.3%. We found all six combined peptide sequences of 222 amino acid ... | ['ADP Ribose Transferases', 'Animals', 'Antigens, Differentiation, T-Lymphocyte', 'Arginine', 'Base Sequence', 'Bone Marrow', 'Chickens', 'Cloning, Molecular', 'DNA Primers', 'DNA, Complementary', 'GPI-Linked Proteins', 'Gene Expression', 'Histocompatibility Antigens', 'Membrane Glycoproteins', 'Molecular Sequence Data... | 7,961,658 | [['D08.811.913.400.725.115'], ['B01.050'], ['D23.050.301.264.894', 'D23.101.100.894'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A15.382.216'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.393.220'], ['D13.695.578.424... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Hemodynamic effects of a new right ventricular assist device. | A right ventricular assist device (VAD) based on the principle of counterpulsation has been developed at our institution. The device is a valveless, pneumatically actuated, 40 cc, sac-type pump, with a single inlet-outlet port. For right ventricular support, the "Uniport" pump is anastamosed end-to-side to the pulmonar... | ['Animals', 'Cardiac Output', 'Cattle', 'Equipment Design', 'Heart Failure', 'Heart-Assist Devices', 'Hemodynamics', 'Male', 'Ventricular Function, Right'] | 2,252,737 | [['B01.050'], ['E01.370.370.380.150', 'G09.330.380.124'], ['B01.050.150.900.649.313.500.380.271'], ['E05.320'], ['C14.280.434'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['G09.330.380'], ['G09.330.955.900']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Retinoic acid regulates insulin-like growth factor II expression in a neuroblastoma cell line. | Insulin-like growth factors (IGF-I and IGF-II) are mitogenic polypeptides that play an important role in normal growth and development. IGF-II has been shown to stimulate the growth of neuroblastoma tumors in an autocrine and paracrine fashion. Critical in determining the role of IGF-II in tumorigenesis is the necessit... | ['Cell Division', 'Cell Line', 'Cell Nucleus', 'DNA Replication', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Insulin-Like Growth Factor II', 'Kinetics', 'Neuroblastoma', 'Poly A', 'RNA', 'RNA, Messenger', 'Thymidine', 'Transcription, Genetic', 'Tretinoin'] | 1,375,906 | [['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G02.111.225', 'G05.226'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.937.420', 'D12.776.124.862.425', 'D12.776.467.937.420', 'D23.529.937... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acetate-bridged platinum(III) complexes derived from cisplatin. | Oxidation of the acetate-bridged half-lantern platinum(II) complex cis-[Pt(II)(NH(3))(2)(ì-OAc)(2)Pt(II)(NH(3))(2)](NO(3))(2), [1](NO(3))(2), with iodobenzene dichloride or bromine generates the halide-capped platinum(III) species cis-[XPt(III)(NH(3))(2)(ì-OAc)(2)Pt(III)(NH(3))(2)X](NO(3))(2), where X is Cl in [2](NO(3... | ['Acetates', 'Cisplatin', 'Crystallography, X-Ray', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Molecular Conformation', 'Organoplatinum Compounds', 'Oxidation-Reduction'] | 22,946,515 | [['D02.241.081.018', 'D10.251.400.045'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E05.196.309.742.225'], ['E05.196.867.519'], ['E05.599.595'], ['G02.111.570.820'], ['D02.691.788'], ['G02.700', 'G03.295.531']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Accurate relief of the die surface of the wax pattern prior to casting. | A quick, simple technique has been described to mark, identify, and remove interferences from the inner surface of a wax pattern. Problems in the seating of simple and complex castings are virtually eliminated. | ['Dental Casting Technique', 'Dental Models', 'Gold Alloys', 'Technology, Dental', 'Waxes'] | 325,202 | [['E06.780.250', 'E06.912.115'], ['E06.261', 'J01.897.280.500.545.129.200', 'L01.178.820.090.545.129.200'], ['D01.379.375', 'D01.552.033.533', 'D25.058.451', 'D25.339.208.534', 'J01.637.051.058.451', 'J01.637.051.339.208.534'], ['E06.912', 'H02.010.800', 'J01.897.724'], ['D10.945']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Thermal sensitivity and protein anti-adsorption of hydroxypropyl cellulose-g- poly(2-(methacryloyloxy) ethyl phosphorylcholine). | Zwitterionic graft copolymers, hydroxypropyl cellulose graft poly(2-(methacryloyloxy) ethyl phosphorylcholine) (HPC-g-PMPC) with well-defined architecture were synthesized by atom transfer radical polymerization (ATRP). The self-assembly behaviors and thermal sensitivity of HPC-g-PMPC copolymers and their correlations ... | ['Adsorption', 'Cellulose', 'Methacrylates', 'Phosphorylcholine', 'Polymers', 'Temperature'] | 27,987,988 | [['G01.030', 'G02.020'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['D02.241.081.069.600'], ['D02.092.877.883.333.700', 'D02.675.276.232.700'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', ... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Cancer Internet search activity on a major search engine, United States 2001-2003. | BACKGROUND: To locate online health information, Internet users typically use a search engine, such as Yahoo! or Google. We studied Yahoo! search activity related to the 23 most common cancers in the United States.OBJECTIVE: The objective was to test three potential correlates of Yahoo! cancer search activity--estimate... | ['Cost of Illness', 'Health Education', 'Humans', 'Incidence', 'Internet', 'Neoplasms', 'Research', 'Survival Analysis', 'United States'] | 15,998,627 | [['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['I02.233.332', 'N02.421.726.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['L01.224.230.110.500'], ['C0... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
The efficacy and persistent anthelmintic effect of ivermectin in sheep. | The direct efficacy and the long-term persistent anthelmintic effect of an oral suspension and an injectable formulation of ivermectin at a dose rate of 0.2 mg kg-1 was studied in sheep. Lambs were infected experimentally with Haemonchus contortus, Trichostrongylus vitrinus and Cooperia curticei. After 3 weeks they wer... | ['Administration, Oral', 'Animals', 'Feces', 'Haemonchiasis', 'Injections, Subcutaneous', 'Intestinal Diseases, Parasitic', 'Ivermectin', 'Parasite Egg Count', 'Sheep', 'Sheep Diseases', 'Trichostrongyloidiasis', 'Trichostrongylosis'] | 8,291,186 | [['E02.319.267.100'], ['B01.050'], ['A12.459'], ['C01.610.335.508.700.775.825.400'], ['E02.319.267.530.620'], ['C01.610.432', 'C06.405.469.452'], ['D02.540.576.500.997'], ['E01.370.225.932.600', 'E05.200.932.600'], ['B01.050.150.900.649.313.500.380.791'], ['C22.836'], ['C01.610.335.508.700.775.825'], ['C01.610.335.508.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Outcomes of childhood conduct problem trajectories in early adulthood: findings from the ALSPAC study. | Although conduct problems in childhood are stably associated with problem outcomes, not every child who presents with conduct problems is at risk. This study extends previous studies by testing whether childhood conduct problem trajectories are predictive of a wide range of other health and behavior problems in early a... | ['Adolescent', 'Age Factors', 'Child', 'Child Development', 'Child, Preschool', 'Conduct Disorder', 'Early Intervention, Educational', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Risk Factors', 'Social Adjustment'] | 24,197,169 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['F03.625.094.300'], ['N02.421.143.130.320', 'N02.421.726.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.45... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficacy and safety of loxapine for inhalation in the treatment of agitation in patients with schizophrenia: a randomized, double-blind, placebo-controlled trial. | OBJECTIVE: The objective of this study was to assess the efficacy and safety of inhaled loxapine in the treatment of agitation in patients with psychotic disorders.METHOD: In this randomized, double-blind, placebo-controlled study, 129 agitated patients with schizophrenia or schizoaffective disorder (DSM-IV criteria) w... | ['Administration, Inhalation', 'Adult', 'Aerosols', 'Antipsychotic Agents', 'Double-Blind Method', 'Drug Administration Schedule', 'Female', 'Humans', 'Loxapine', 'Male', 'Middle Aged', 'Psychomotor Agitation', 'Psychotic Disorders', 'Treatment Outcome', 'Young Adult'] | 21,294,997 | [['E02.319.267.050'], ['M01.060.116'], ['D20.280.055', 'D26.255.165.055'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Attachment of bacterial cells to carbon electrodes. | Anodic stripping method was applied to analyze the process of bacterial attachment to the surface of carbon-paste electrodes (CPE). The electrode was immersed for various times in a bacterial cell suspension to allow the cells to attach to its surface. The number of bacterial cells attached to the electrode surface inc... | ['Bacterial Adhesion', 'Carbon', 'Coloring Agents', 'Electrodes', 'Oxidation-Reduction'] | 10,790,776 | [['G06.099.050'], ['D01.268.150'], ['D27.720.233'], ['E07.305.250'], ['G02.700', 'G03.295.531']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and biological activity of unusual nucleosides having 3,4-bis(hydroxymethyl) thietane ring as a sugar moiety. | The enantiomerically pure synthesis of 9-[(2'S, 3'S)-bis(hydroxymethyl)thietan-1'-yl]adenine 2,3'-thio analog of oxetanocin A, was achieved via coupling of silylated 6-chloropurine and sulfoxide 16 under Pummerer reaction conditions. | ['Adenine', 'Antiviral Agents', 'Indicators and Reagents', 'Molecular Structure'] | 10,780,351 | [['D03.633.100.759.138'], ['D27.505.954.122.388'], ['D27.720.470.410'], ['G02.111.570', 'G02.466']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Agenesis of the corpus callosum: magnetic resonance imaging. | Three patients who had complete agenesis and two patients who had partial agenesis of the corpus callosum (ACC) underwent magnetic resonance (MR) imaging. In addition to excellent visualization of the indirect signs of ACC, direct vivid display (short T1) of the corpus callosum on sagittal images allowed better evaluat... | ['Agenesis of Corpus Callosum', 'Humans', 'Magnetic Resonance Spectroscopy'] | 3,983,387 | [['C10.500.034', 'C16.131.666.034', 'C23.300.008'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.867.519']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of the transition to ICD-10 on Medicare inpatient hospital payments. | OBJECTIVE: On October 1, 2013, the reporting of diagnoses and procedures in the U.S. will transition from the clinical modification of the ninth revision of the International Classification of Diseases (ICD-9-CM) to the tenth revision (ICD-10). We estimate the impact of conversion to ICD-10 on Medicare MS-DRG payment... | ['Diagnosis-Related Groups', 'Economics, Hospital', 'Humans', 'Inpatients', 'International Classification of Diseases', 'Medicare', 'Reimbursement Mechanisms', 'United States'] | 22,340,773 | [['N03.219.521.710.305.200.080'], ['N03.219.262'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['L01.453.245.945.400'], ['N03.219.521.346.506.564.663', 'N03.219.521.576.343.840', 'N03.706.615.696'], ['N03.219.521.710.305'], ['Z01.107.567.875']] | ['Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Anatomopathological findings in hangings: a retrospective autopsy study. | BACKGROUND: In this retrospective autopsy study, we aimed to review the anatomopathological findings observed in cases of hanging death for a five year period and to evaluate the role of contributing factors such as age, sex, type of hanging and localization of the ligature knot.METHODS: Autopsy reports of 102 hanging ... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Asphyxia', 'Ecchymosis', 'Female', 'Forensic Pathology', 'Humans', 'Male', 'Middle Aged', 'Neck Injuries', 'Purpura', 'Retrospective Studies', 'Sex Distribution', 'Suicide', 'Turkey', 'Young Adult'] | 23,275,431 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.260.095', 'C26.103'], ['C15.378.100.452', 'C23.550.414.625', 'C23.888.885.312'], ['H02.403.330.300', 'H02.403.650.249', 'I01.198.780.937.460'], ['B01.050.150.900.649.313.988.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Prophylaxis of neutropenic fever with ciprofloxacin in patients with acute myeloid leukemia treated with intensive chemotherapy. | AIMS: Neutropenic fever is one of the most serious complications after induction chemotherapy in acute myeloid leukemia (AML). Prophylaxis with antibiotics for prevention of neutropenic fever in AML is controversial and there are few studies on this issue from developing countries.METHODS: In this retrospective study, ... | ['Adolescent', 'Aged', 'Antibiotic Prophylaxis', 'Ciprofloxacin', 'Female', 'Fever', 'Humans', 'Incidence', 'Induction Chemotherapy', 'Leukemia, Myeloid, Acute', 'Male', 'Middle Aged', 'Neutropenia', 'Retrospective Studies'] | 24,330,539 | [['M01.060.057'], ['M01.060.116.100'], ['E02.319.162.150', 'E02.319.703.150'], ['D03.633.100.810.835.322.186'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E02.319.499', 'E02.860... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular cloning, overproduction, purification and biochemical characterization of the p39 nsp2 protease domains encoded by three alphaviruses. | Alphaviruses cause serious diseases that pose a potential health threat to both humans and livestock. The nonstructural protein 2 (nsp2) encoded by alphaviruses is a multifunctional enzyme that is essential for viral replication and maturation. Its 39-kDa C-terminal domain (nsp2pro) is a cysteine protease that is respo... | ['Alphavirus', 'Cloning, Molecular', 'Cysteine Endopeptidases', 'Dithiothreitol', 'Edetic Acid', 'Glycerol', 'Humans', 'Hydrogen-Ion Concentration', 'Mercaptoethanol', 'Molecular Weight', 'Phosphines', 'Protein Structure, Tertiary', 'Recombinant Fusion Proteins', 'Sodium Chloride', 'Substrate Specificity', 'Temperature... | 19,013,248 | [['B04.820.578.875.054'], ['E05.393.220'], ['D08.811.277.656.262.500', 'D08.811.277.656.300.200'], ['D02.033.800.196', 'D02.886.740.224', 'D09.853.196'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], ['D02.033.800.875.500', 'D09.853.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D02.03... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Hip fracture rates in Hong Kong and the United States, 1988 through 1989. | OBJECTIVES: Prior studies have suggested that hip fracture rates are substantially lower in Asian countries than in the United States. However, comparisons have been limited by unavailability of recent data, differences in case definition, lack of data from similar time periods, and small sample sizes. This study sough... | ['Aged', 'Aged, 80 and over', 'Female', 'Hip Fractures', 'Hong Kong', 'Hospital Records', 'Humans', 'Male', 'Middle Aged', 'Sex Ratio', 'United States'] | 8,484,451 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['Z01.252.474.164.450'], ['E05.318.308.940.425', 'L01.399.250.900.425', 'N04.452.859.380', 'N05.715.360.300.715.380', 'N06.850.520.308.940.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Non-ionic surfactants as novel intranasal absorption enhancers: in vitro and in vivo characterization. | OBJECTIVE: To explore the potential of non-ionic surfactants as novel intranasal absorption enhancers.METHODS: Taking sumatriptan succinate (SMS) as a model drug, influence of different non-ionic surfactants, including laurate sucrose ester (SE), cremophor EL and poloxamer 188, on the intranasal absorption of SMS was i... | ['Administration, Intranasal', 'Animals', 'Biological Availability', 'Chemistry, Pharmaceutical', 'Glycerol', 'Laurates', 'Male', 'Nasal Absorption', 'Nasal Mucosa', 'Poloxamer', 'Rats', 'Rats, Sprague-Dawley', 'Sumatriptan', 'Surface-Active Agents'] | 25,347,689 | [['E02.319.267.120.655.500'], ['B01.050'], ['G03.787.151', 'G07.690.725.129'], ['H01.158.703.007', 'H01.181.466'], ['D02.033.800.875.500', 'D09.853.875.500'], ['D10.251.500.410'], ['G03.015.500.703.500', 'G03.787.024.500.703.500', 'G07.690.725.015.500.703.500', 'G09.772.813.500'], ['A04.531.520', 'A04.760.600', 'A10.61... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
NOV (CCN3) regulation in the growth plate and CCN family member expression in cartilage neoplasia. | Growth plate chondrocytes undergo a coordinated differentiation process resulting in terminal differentiation and new bone formation. Enchondromas are pre-malignant, benign cartilaginous lesions that arise from growth plate chondrocytes that fail to undergo terminal differentiation. NOV (nephroblastoma overexpressed) i... | ['Animals', 'Bone Neoplasms', 'CCN Intercellular Signaling Proteins', 'Cartilage Diseases', 'Chondrocytes', 'Chondroma', 'Chondrosarcoma', 'Connective Tissue Growth Factor', 'Culture Media', 'Cysteine-Rich Protein 61', 'Femur', 'Gene Expression Regulation, Neoplastic', 'Growth Plate', 'Humans', 'Hypertrophy', 'Immediat... | 14,648,665 | [['B01.050'], ['C04.588.149', 'C05.116.231'], ['D12.644.276.200', 'D12.776.467.200', 'D12.776.860.300.200', 'D23.529.237'], ['C05.182', 'C17.300.182'], ['A11.329.171'], ['C04.557.450.565.265'], ['C04.557.450.565.280', 'C04.557.450.795.300'], ['D12.644.276.200.100', 'D12.776.467.200.100', 'D12.776.860.300.200.100', 'D23... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Structural characteristics and bioactive properties of a novel polysaccharide from Flammulina velutipes. | A new water-soluble polysaccharide (FVP1) was extracted from Flammulina velutipes by traditional method "water extraction and alcohol precipitation" and purified by column chromatography. Physicochemical characterization showed that FVP1 was a homogeneous polysaccharide with a relative molecular weight of 54.78 kDa. It... | ['Animals', 'Cell Survival', 'Cells, Cultured', 'DNA, Viral', 'Dose-Response Relationship, Drug', 'Flammulina', 'Hep G2 Cells', 'Hepatitis B Surface Antigens', 'Hepatitis B e Antigens', 'Hepatitis B virus', 'Humans', 'Mice', 'Microbial Sensitivity Tests', 'Molecular Weight', 'Polysaccharides', 'RAW 264.7 Cells', 'Struc... | 30,007,599 | [['B01.050'], ['G04.346'], ['A11.251'], ['D13.444.308.568'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.300.179.100.320'], ['A11.251.860.180.432', 'A11.436.348.500'], ['D23.050.327.495.500.475'], ['D23.050.327.495.500.469'], ['B04.280.375.650.425', 'B04.450.390.650.425'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pituitary and adrenal control of pancreatic endocrine function in the duck. | Recent clinical and immunological data suggest that the classical concept of "idiopathic autoimmune diseases" is to be revised. In a normal population, autoimmunity reactions against thyroid gland, gastric mucosa and adrenals develop slowly with increasing age and are found more frequently in women than in men (at leas... | ['Animals', 'Blood Glucose', 'Corticosterone', 'Ducks', 'Fasting', 'Glucagon', 'Glucose', 'Growth Hormone', 'Hypophysectomy', 'Islets of Langerhans', 'Male', 'Pituitary Gland', 'Pituitary Gland, Anterior', 'Pituitary-Adrenal System'] | 789,141 | [['B01.050'], ['D09.947.875.359.448.500'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['B01.050.150.900.248.050.200', 'B01.050.150.900.248.690.345'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['D09.947.875.359.448'], ['D06... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ultrasound assessment of endometrial cavity in perimenopausal women on oral progesterone for abnormal uterine bleeding: comparison of diagnostic accuracy of imaging with hysteroscopy-guided biopsy. | AIM: To investigate the effect of oral progesterone on the accuracy of imaging studies performed to detect endometrial pathology in comparison to hysteroscopy-guided biopsy in perimenopausal women on progesterone treatment for abnormal uterine bleeding.METHODS: The study population comprised of women aged 40-55 years w... | ['Adult', 'Biopsy', 'Endometrium', 'Female', 'Humans', 'Hysteroscopy', 'Middle Aged', 'Perimenopause', 'Progesterone', 'Progestins', 'Sensitivity and Specificity', 'Ultrasonography', 'Uterine Hemorrhage'] | 21,733,032 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A05.360.319.679.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.378.330', 'E01.370.388.250.360', 'E04.502.250.360', 'E04.520.360', 'E04.950... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The first cohort of Iranian patients with hyper immunoglobulin E syndrome: A long-term follow-up and genetic analysis. | BACKGROUND: Hyper-IgE syndromes (HIES) are distinct diseases characterized by recurrent cutaneous and lung infections, eczema, and elevated serum IgE level.METHODS: In this study, clinical manifestations, immunologic findings, and genetic studies of all patients with HIES in the Iranian national registry database were ... | ['Adolescent', 'Adult', 'Child', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Guanine Nucleotide Exchange Factors', 'Humans', 'Immunoglobulin E', 'Infections', 'Iran', 'Job Syndrome', 'Lung', 'Male', 'Mutation', 'STAT3 Transcription Factor', 'Skin', 'Young Adult'] | 30,801,830 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D12.644.360.325.300', 'D12.776.476.325.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Reproduction and hatchling performance in freshwater turtles associated with a remediated coal fly-ash spill. | In 2008 an impoundment retaining wall failed at the Tennessee Valley Authority's coal burning plant in Kingston, Tennessee, releasing large quantities of coal-fly ash into the Emory River. Following extensive remediation of the spill, we captured (in 2011 and 2012) gravid turtles of multiple species in three rivers (tw... | ['Animals', 'Coal Ash', 'Environmental Exposure', 'Environmental Monitoring', 'Female', 'Male', 'Mass Spectrometry', 'Reproduction', 'Rivers', 'Species Specificity', 'Tennessee', 'Turtles', 'Water Pollutants, Chemical'] | 25,682,257 | [['B01.050'], ['D20.633.110'], ['N06.850.460.350'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E05.196.566'], ['G08.686.784'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['G16.824'], ['Z01.107.567.875.075.775'], ['B01.050.150.900.833.848'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Theflavins and theasinensin A derived from fermented tea have antihyperglycemic and hypotriacylglycerolemic effects in KK-A(y) mice and Sprague-Dawley rats. | Although tea polyphenols are reported to improve serum glucose and lipid levels by inhibiting amylase activity and reducing lipid absorption, in vivo data are lacking. We evaluated in vivo the antihyperglycemic and hypotriacylglycerolemic effects of theaflavins (TFs) and theasinensin A (TSA) refined from fermented tea ... | ['Animals', 'Benzopyrans', 'Biflavonoids', 'Camellia sinensis', 'Catechin', 'Diabetes Mellitus, Type 2', 'Dietary Supplements', 'Eriobotrya', 'Fermentation', 'Gallic Acid', 'Hypertriglyceridemia', 'Hypoglycemic Agents', 'Hypolipidemic Agents', 'Japan', 'Male', 'Mice', 'Mice, Inbred Strains', 'Phenols', 'Plant Leaves', ... | 24,011,231 | [['B01.050'], ['D03.383.663.283', 'D03.633.100.150'], ['D03.383.663.283.266.450.190', 'D03.633.100.150.266.450.190'], ['B01.650.940.800.575.912.250.341.998.500.500'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['C18.452.394.750.149', 'C19.246.30... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Lipid specificity of the membrane binding domain of coagulation factor X. | Essentials Membrane-binding GLA domains of coagulation factors are essential for proper clot formation. Factor X (FX) is specific to phosphatidylserine (PS) lipids through unknown atomic-level interactions. Molecular dynamics simulations were used to develop the first membrane-bound model of FX-GLA. PS binding modes of... | ['1-Carboxyglutamic Acid', 'Animals', 'Binding Sites', 'Cattle', 'Cell Membrane', 'Factor X', 'Kinetics', 'Molecular Docking Simulation', 'Phosphatidylserines', 'Protein Binding', 'Protein Interaction Domains and Motifs', 'Structure-Activity Relationship'] | 28,782,177 | [['D02.241.081.901.400', 'D12.125.067.625.174', 'D12.125.119.409.174'], ['B01.050'], ['G02.111.570.120'], ['B01.050.150.900.649.313.500.380.271'], ['A11.284.149'], ['D08.622.471', 'D12.776.124.125.400', 'D12.776.811.243.471', 'D23.119.400'], ['G01.374.661', 'G02.111.490'], ['E05.599.595.249', 'L01.224.160.249'], ['D10.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Ventilator-associated pneumonia in patients assisted by veno-arterial extracorporeal membrane oxygenation support: Epidemiology and risk factors of treatment failure. | INTRODUCTION: Ventilator-associated pneumonia (VAP) is frequent in Intensive Care Unit (ICU) patients. In the specific case of patients treated with Veno-Arterial Extracorporeal Membrane Oxygenation Support (VA-ECMO), VAP treatment failures (VAP-TF) have been incompletely investigated.METHODS: To investigate the risk f... | ['Adult', 'Aged', 'Comorbidity', 'Extracorporeal Membrane Oxygenation', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pneumonia, Ventilator-Associated', 'Risk Factors', 'Treatment Failure', 'Treatment Outcome'] | 29,652,913 | [['M01.060.116'], ['M01.060.116.100'], ['N05.715.350.225', 'N06.850.490.687'], ['E02.880.301', 'E04.292.451'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C01.248.250.500', 'C01.748.610.300.500', 'C08.381.677.300.500', 'C08.730.610.300.500', 'C23.550.291.875.500.500.500'], ['E05.318.740.600.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
On possible existence of pseudobinary mixed valence fluorides of Ag(I)/Ag(II): a DFT study. | The DFT calculations performed within local density approximation disclose conceivable existence of two novel mixed-valence Ag(I)/Ag(II) fluorides, Ag(2)F(3), i.e., Ag(I)Ag(II)F(3) and Ag(3)F(4), i.e., Ag(I)(2)Ag(II)F(4). Ag(2)F(3) is predicted to crystallize in three equally stable NaCuF(3)-, KAgF(3)-, or CuTeO(3)-typ... | ['Algorithms', 'Computer Simulation', 'Crystallography', 'Electrochemistry', 'Fluorides', 'Models, Chemical', 'Molecular Structure', 'Silver Compounds', 'Thermodynamics'] | 21,258,832 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['E05.196.309', 'H01.181.529.240'], ['H01.181.529.307'], ['D01.248.497.158.380', 'D01.303.350.300'], ['E05.599.495'], ['G02.111.570', 'G02.466'], ['D01.847'], ['G01.906']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Role of cranial sutures in normal and abnormal skull development. | In a series of experimental studies, the effects of induced premature closure of a normal cranial suture on the normal growth pattern of the rabbit skull are reported. In general, the results indicate that the craniofacial skeleton is an integrated growing unit in which alteration in growth of one component has profoun... | ['Animals', 'Cranial Sutures', 'Rabbits', 'Skull'] | 1,821,301 | [['B01.050'], ['A02.835.232.781.200'], ['B01.050.150.900.649.313.968.700'], ['A02.835.232.781']] | ['Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of equine herpesvirus 1 glycoprotein D by using a recombinant baculovirus. | Glycoprotein D (gD) of equine herpesvirus 1 (EHV-1) was expressed at the surface of insect cells infected by a recombinant baculovirus. EHV-1 gD was detected as multiple forms (56, 52, and 48 kDa) from 18 to 96 h postinfection. Laboratory animals inoculated with the recombinant EHV-1 gD developed neutralizing antibody ... | ['Animals', 'Cloning, Molecular', 'Fluorescent Antibody Technique', 'Herpesvirus 1, Equid', 'Moths', 'Neutralization Tests', 'Nucleopolyhedroviruses', 'Viral Envelope Proteins'] | 8,411,384 | [['B01.050'], ['E05.393.220'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B04.280.382.100.900.430'], ['B01.050.500.131.617.720.500.500.937.650'], ['E01.370.225.812.735.550', 'E05.200.812.735.550', 'E05.478.594.760.550'], ['B... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modeling variation in interaction strength between barnacles and fucoids. | The strength by which species interact can vary throughout their ontogeny, as environments vary in space and time, and with the density of their populations. Characterizing strengths of interaction in situ for even a small number of species is logistically difficult and may apply only to those conditions under which th... | ['Animals', 'Ascophyllum', 'Models, Biological', 'Mortality', 'New England', 'Population Density', 'Population Dynamics', 'Reproduction', 'Thoracica', 'Time Factors'] | 18,975,013 | [['B01.050'], ['B01.750.600.040'], ['E05.599.395'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550', 'N06.850.520.308.985.550'], ['Z01.107.567.875.550'], ['N01.224.600', 'N06.850.505.400.600'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['G08.686.784'], ['B01.050.500.131.365.880'], ['G0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Capillary electrophoresis to quantitate gossypol enantiomers in cotton flower petals and seed. | Gossypol is a toxic compound that occurs as a mixture of enantiomers in cotton plant tissues including seed and flower petals. The (-)-enantiomer is more toxic to non-ruminant animals. Efforts to breed cottonseed with a low percentage of (-)-gossypol requires determination of the (+)- to (-)-gossypol ratio in seed and ... | ['Electrophoresis, Capillary', 'Flowers', 'Gossypium', 'Gossypol', 'Hydrogen-Ion Concentration', 'Limit of Detection', 'Reproducibility of Results', 'Seeds', 'Spectrophotometry, Ultraviolet', 'Stereoisomerism', 'Temperature'] | 23,122,406 | [['E05.196.401.190', 'E05.301.300.190'], ['A18.024.249.500'], ['B01.650.940.800.575.912.250.859.821.500.244'], ['D02.455.849.765.444'], ['G02.300'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['A18.024.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Double termination of the alimentary tract in females: a report of 12 cases and a literature review. | Twelve female infants with double termination of the alimentary tract were reported. One patient had a high rectovaginal fistula, but in the other 11 cases the tract opened into the bowel uniformly at the level of the levator ani (anorectal-vestibular fistula). In these patients, diagnosis of the anatomical level of th... | ['Anal Canal', 'Female', 'Humans', 'Infant, Newborn', 'Methods', 'Pregnancy', 'Radiography', 'Rectal Fistula', 'Rectovaginal Fistula', 'Rectum', 'Vagina'] | 6,747,793 | [['A03.556.124.526.070', 'A03.556.249.249.070'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E05.581'], ['G08.686.784.769'], ['E01.370.350.700'], ['C06.267.550.600', 'C06.405.469.471.600', 'C06.405.469.860.752', 'C23.300.575.185.550.600'], ['C06.267.550.600.650', 'C06.405.469.471.600.650', '... | ['Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Association between sphericity, ventricular function and size of the infarction in rats]. | BACKGROUND: The left ventricular (LV) sphericity is a factor associated with ventricular dysfunction, but it is not well-characterized in the experimental infarction model in rats.OBJECTIVE: To analyze the association between the sphericity index (SI), the ventricular function and the infarcted area in an experimental ... | ['Animals', 'Disease Models, Animal', 'Heart Ventricles', 'Linear Models', 'Male', 'Myocardial Infarction', 'Rats', 'Stress, Mechanical', 'Ventricular Function, Left', 'Ventricular Remodeling'] | 20,379,618 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A07.541.560'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
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